PedAM
Pediatric Disease Annotations & Medicines
| mucinous adenocarcinoma | ||||
| Disease ID | 1281 |
|---|---|
| Disease | mucinous adenocarcinoma |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:9) HP:0002664 | Neoplasia | 6 HP:0010447 | Fistula in ano | 3 HP:0100570 | Carcinoid tumor | 3 HP:0000718 | Aggressive behaviour | 2 HP:0002608 | Celiac disease | 1 HP:0100590 | Rectal fistula | 1 HP:0030731 | Carcinoma | 1 HP:0001696 | Situs inversus totalis | 1 HP:0009792 | Teratoma | 1 |
| Disease ID | 1281 |
|---|---|
| Disease | mucinous adenocarcinoma |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:2) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs113488022 | 22522845 | 673 | BRAF | umls:C0007130 | BeFree | BRAF V600E mutation and CpG island methylation phenotype-positive status are similar in signet ring cell carcinoma and mucinous adenocarcinoma but more frequent when compared with conventional adenocarcinoma. | 0.002171535 | 2012 | BRAF | 7 | 140753336 | A | T,G,C |
| rs121434568 | 23143308 | 1956 | EGFR | umls:C0007130 | BeFree | Here, we show that haploinsufficiency of Nkx2-1 in combination with oncogenic Kras(G12D), but not with oncogenic EGFR(L858R), caused pulmonary tumors in transgenic mice that were phenotypically similar to human mucinous adenocarcinomas. | 0.005081451 | 2012 | EGFR | 7 | 55191822 | T | G |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0007130 | diethylstilbestrol | D004054 | 56-53-1 | adenocarcinoma, mucinous | MESH:D002288 | marker/mechanism | 7672708 | ||
| C0007130 | fluorouracil | D005472 | 51-21-8 | adenocarcinoma, mucinous | MESH:D002288 | marker/mechanism | 15228453 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |