PedAM

Pediatric Disease Annotations & Medicines


	mononeuropathy

Disease ID	1854
Disease	mononeuropathy
Definition	Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ISCHEMIA; traumatic injury; compression; CONNECTIVE TISSUE DISEASES; CUMULATIVE TRAUMA DISORDERS; and other conditions.
Synonym	mononeuropathies mononeuropathies [disease/finding] mononeuropathy (disorder) single damaged nerve
DOID	DOID:1188
UMLS	C0494491
MeSH	D020422
SNOMED-CT	SNOMEDCT_US_2016_09_01:128189008
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:12) C0004096 \| asthma \| 2 C0043117 \| idiopathic thrombocytopenic purpura (itp) \| 1 C0019158 \| hepatitis \| 1 C0042384 \| vasculitis \| 1 C0019163 \| hepatitis b \| 1 C0015464 \| facial palsy \| 1 C0235025 \| motor neuropathy \| 1 C0026975 \| myelitis \| 1 C0085273 \| parvovirus b19 infection \| 1 C0034150 \| purpura \| 1 C0152025 \| polyneuropathy \| 1 C0043117 \| idiopathic thrombocytopenic purpura \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:102) 8935 \| SKAP2 \| DISEASES 973 \| CD79A \| DISEASES 4353 \| MPO \| DISEASES 8050 \| PDHX \| DISEASES 8078 \| USP5 \| DISEASES 55907 \| CMAS \| DISEASES 5657 \| PRTN3 \| DISEASES 7276 \| TTR \| DISEASES 4852 \| NPY \| DISEASES 2354 \| FOSB \| DISEASES 3976 \| LIF \| DISEASES 9098 \| USP6 \| DISEASES 64151 \| NCAPG \| DISEASES 4298 \| MLLT1 \| DISEASES 314 \| AOC2 \| DISEASES 6737 \| TRIM21 \| DISEASES 1401 \| CRP \| DISEASES 80896 \| NPL \| DISEASES 3569 \| IL6 \| DISEASES 4836 \| NMT1 \| DISEASES 6741 \| SSB \| DISEASES 3417 \| IDH1 \| DISEASES 1419 \| CRYGB \| DISEASES 9172 \| MYOM2 \| DISEASES 7434 \| VIPR2 \| DISEASES 10552 \| ARPC1A \| DISEASES 3553 \| IL1B \| DISEASES 5276 \| SERPINI2 \| DISEASES 6507 \| SLC1A3 \| DISEASES 3371 \| TNC \| DISEASES 2028 \| ENPEP \| DISEASES 1181 \| CLCN2 \| DISEASES 51083 \| GAL \| DISEASES 5286 \| PIK3C2A \| DISEASES 150094 \| SIK1 \| DISEASES 4851 \| NOTCH1 \| DISEASES 1737 \| DLAT \| DISEASES 22934 \| RPIA \| DISEASES 6051 \| RNPEP \| DISEASES 7349 \| UCN \| DISEASES 23588 \| KLHDC2 \| DISEASES 1632 \| ECI1 \| DISEASES 6037 \| RNASE3 \| DISEASES 6869 \| TACR1 \| DISEASES 25928 \| SOSTDC1 \| DISEASES 2915 \| GRM5 \| DISEASES 6504 \| SLAMF1 \| DISEASES 2353 \| FOS \| DISEASES 344561 \| GPR148 \| DISEASES 5376 \| PMP22 \| DISEASES 57381 \| RHOJ \| DISEASES 6863 \| TAC1 \| DISEASES 7433 \| VIPR1 \| DISEASES 9735 \| KNTC1 \| DISEASES 8811 \| GALR2 \| DISEASES 3418 \| IDH2 \| DISEASES 9939 \| RBM8A \| DISEASES 885 \| CCK \| DISEASES 7317 \| UBA1 \| DISEASES 9516 \| LITAF \| DISEASES 9639 \| ARHGEF10 \| DISEASES 80320 \| SP6 \| DISEASES 4771 \| NF2 \| DISEASES 23764 \| MAFF \| DISEASES 8650 \| NUMB \| DISEASES 7068 \| THRB \| DISEASES 23644 \| EDC4 \| DISEASES 617 \| BCS1L \| DISEASES 26047 \| CNTNAP2 \| DISEASES 4000 \| LMNA \| DISEASES 4803 \| NGF \| DISEASES 1369 \| CPN1 \| DISEASES 959 \| CD40LG \| DISEASES 26036 \| ZNF451 \| DISEASES 4068 \| SH2D1A \| DISEASES 8879 \| SGPL1 \| DISEASES 9452 \| ITM2A \| DISEASES 4153 \| MBL2 \| DISEASES 6572 \| SLC18A3 \| DISEASES 1896 \| EDA \| DISEASES 3339 \| HSPG2 \| DISEASES 54829 \| ASPN \| DISEASES 7133 \| TNFRSF1B \| DISEASES 1041 \| CDSN \| DISEASES 7436 \| VLDLR \| DISEASES 254251 \| LCORL \| DISEASES 4099 \| MAG \| DISEASES 2591 \| GALNT3 \| DISEASES 654364 \| NME1-NME2 \| DISEASES 5091 \| PC \| DISEASES 6164 \| RPL34 \| DISEASES 6916 \| TBXAS1 \| DISEASES 6336 \| SCN10A \| DISEASES 7124 \| TNF \| DISEASES 7086 \| TKT \| DISEASES 54900 \| LAX1 \| DISEASES 3920 \| LAMP2 \| DISEASES 116 \| ADCYAP1 \| DISEASES 54551 \| MAGEL2 \| DISEASES 567 \| B2M \| DISEASES 101 \| ADAM8 \| DISEASES 820 \| CAMP \| DISEASES
Locus	(Waiting for update.)

Disease ID	1854
Disease	mononeuropathy
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:10) HP:0002099 \| Asthma \| 2 HP:0012115 \| Liver inflammation \| 1 HP:0001880 \| Eosinophilia \| 1 HP:0010628 \| Facial palsy, unilateral or bilateral \| 1 HP:0000979 \| Purpura \| 1 HP:0200120 \| Chronic active hepatitis \| 1 HP:0012486 \| Inflammation of spinal cord \| 1 HP:0003201 \| Rhabdomyolysis \| 1 HP:0001271 \| Polyneuropathy \| 1 HP:0002633 \| Vasculitis \| 1

Disease ID	1854
Disease	mononeuropathy
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:5)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0494491	cyclophosphamide	D003520	50-18-0	mononeuropathies	MESH:D020422	therapeutic	9146079
C0494491	fluorouracil	D005472	51-21-8	mononeuropathies	MESH:D020422	marker/mechanism	732337
C0494491	pravastatin	D017035	81093-37-0	mononeuropathies	MESH:D020422	marker/mechanism	17133326
C0494491	tretinoin	D014212	302-79-4	mononeuropathies	MESH:D020422	marker/mechanism	10203107
C0494491	vincristine	D014750	-	mononeuropathies	MESH:D020422	marker/mechanism	169494

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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