PedAM
Pediatric Disease Annotations & Medicines
| mononeuritis multiplex | ||||
| Disease ID | 1188 |
|---|---|
| Disease | mononeuritis multiplex |
| Definition | WHAT: Mononeuritis multiplex.sMononeuritis Multiplex: the simultaneous inflammation or degeneration of two or more peripheral nerves which are remote from one another.sWHY:sMononeuritis multiplex can occur in polyarteritis if the nutrient arteries of peripheral nerve trunks are involved by the disease.sHOW:sThe patient with mononeuritis multiplex may present with motor or sensory changes which occur in an irregular and asymmetrical distribution on his body. These changes may be areas of paresthesia or anesthesia, loss of deep tendon reflexes, weakness or paralysis of muscle group. For example, a typical patient might present with paresthesia of the radial aspect of his left hand representing involvement of the left median nerve and weakness of his right foot and ankle representing right tibial nerve involvement.sREFS:s1) Lovshin, LL and Kernohan, JW: Peripheral neuritis in periarteritis nodosa: a clinicopathologic study. Proc Staff Meeting Mayo Clinic 24:48, 1949. DN19294-5. 2) Frohnert, PP and Sheps, SG: Long-term follow-up study of periarteritis nodosa. Am J Med 43:8, 1967. DN19295-3. |
| Synonym | mononeuritis multiplex (disorder) |
| DOID | |
| ICD10 | |
| UMLS | C0151295 |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:8) C0042384 | vasculitis | 3 C0008728 | churg-strauss syndrome | 2 C0442874 | neuropathy | 1 C0023448 | lymphocytic leukaemia | 1 C0152025 | polyneuropathies | 1 C0026848 | myopathy | 1 C0033838 | kimura disease | 1 C0021053 | immune disease | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:31) 973 | CD79A | DISEASES 4353 | MPO | DISEASES 55907 | CMAS | DISEASES 5657 | PRTN3 | DISEASES 4298 | MLLT1 | DISEASES 6737 | TRIM21 | DISEASES 1401 | CRP | DISEASES 6741 | SSB | DISEASES 3417 | IDH1 | DISEASES 9172 | MYOM2 | DISEASES 2028 | ENPEP | DISEASES 939 | CD27 | DISEASES 710 | SERPING1 | DISEASES 2206 | MS4A2 | DISEASES 760 | CA2 | DISEASES 9607 | CARTPT | DISEASES 1632 | ECI1 | DISEASES 3418 | IDH2 | DISEASES 4771 | NF2 | DISEASES 462 | SERPINC1 | DISEASES 959 | CD40LG | DISEASES 2833 | CXCR3 | DISEASES 10673 | TNFSF13B | DISEASES 50943 | FOXP3 | DISEASES 1041 | CDSN | DISEASES 4099 | MAG | DISEASES 6164 | RPL34 | DISEASES 7124 | TNF | DISEASES 3106 | HLA-B | DISEASES 727897 | MUC5B | DISEASES 567 | B2M | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1188 |
|---|---|
| Disease | mononeuritis multiplex |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:10) HP:0002633 | Vasculitis | 3 HP:0003198 | Myopathic changes | 1 HP:0001399 | Liver failure | 1 HP:0100758 | Gangrene | 1 HP:0001291 | Cranial nerve disease | 1 HP:0003474 | Sensory impairment | 1 HP:0012089 | Arteritis | 1 HP:0002955 | Granulomatosis | 1 HP:0004448 | Fulminant hepatic failure | 1 HP:0002960 | Autoimmune condition | 1 |
| Disease ID | 1188 |
|---|---|
| Disease | mononeuritis multiplex |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:5) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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All Snps(Total Genotypes:0) | |
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GWASdb Annotation(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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Mapped by lexical matching(Total Items:0) |
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Mapped by homologous gene(Total Items:0) |
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Chemical(Total Drugs:0) | |
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FDA approved drug and dosage information(Total Drugs:0) | |
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FDA labeling changes(Total Drugs:0) | |
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