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PedAM

Pediatric Disease Annotations & Medicines



   mental depression
  

Disease ID 1036
Disease mental depression
Definition
Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders.
Synonym
[x] depression nos
[x]depression nos
depressed state
depression
depression (disease)
depression (emotion)
depression (finding)
depression mental
depression nos
depression nos (disorder)
depression psychic
depression, mental
depression, nos
depressions
depressive state nos
monopolar depression
DOID
UMLS
C0011570
MeSH
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:512)
C0011847  |  diabetes  |  286
C0003467  |  anxiety  |  218
C0497327  |  dementia  |  115
C0011860  |  type 2 diabetes  |  110
C0018799  |  heart disease  |  86
C0030567  |  parkinson's disease  |  82
C0010068  |  coronary heart disease  |  62
C0042373  |  vascular disease  |  62
C0028754  |  obesity  |  62
C0014544  |  epilepsy  |  61
C0005586  |  bipolar disorder  |  60
C0026769  |  multiple sclerosis  |  58
C0018801  |  heart failure  |  55
C0011849  |  diabetes mellitus  |  51
C0006142  |  breast cancer  |  50
C0007222  |  cardiovascular disease  |  46
C0004096  |  asthma  |  45
C0002395  |  alzheimer's disease  |  39
C0683323  |  physical illness  |  38
C0036341  |  schizophrenia  |  38
C0019158  |  hepatitis  |  35
C0033975  |  psychosis  |  35
C0003469  |  anxiety disorder  |  34
C0149931  |  migraine  |  31
C0679466  |  cognitive deficits  |  31
C0020538  |  hypertension  |  30
C0010068  |  coronary artery disease  |  29
C0019196  |  hepatitis c  |  29
C0041696  |  major depressive disorder  |  29
C0003864  |  arthritis  |  28
C0024117  |  chronic obstructive pulmonary disease  |  27
C0003873  |  rheumatoid arthritis  |  25
C0016053  |  fibromyalgia  |  25
C0027051  |  myocardial infarct  |  25
C0027051  |  myocardial infarction  |  24
C0011860  |  type 2 diabetes mellitus  |  24
C0037317  |  sleep disturbance  |  24
C0024115  |  pulmonary disease  |  23
C0600260  |  obstructive pulmonary disease  |  23
C0033860  |  psoriasis  |  23
C0030567  |  parkinson disease  |  21
C0948265  |  metabolic syndrome  |  19
C0002766  |  analgesia  |  19
C0242379  |  lung cancer  |  18
C0003469  |  anxiety disorders  |  18
C0024117  |  chronic obstructive pulmonary disease (copd)  |  15
C0033953  |  sexual dysfunction  |  14
C0013473  |  eating disorder  |  14
C0022661  |  chronic kidney disease  |  13
C0022658  |  kidney disease  |  13
C0011854  |  type 1 diabetes  |  12
C0002020  |  alexithymia  |  12
C0037317  |  sleep disturbances  |  12
C0014556  |  temporal lobe epilepsy  |  11
C0264716  |  chronic heart failure  |  11
C0021359  |  infertility  |  11
C0030319  |  panic disorder  |  10
C0376358  |  prostate cancer  |  10
C0018799  |  cardiac disease  |  10
C0027765  |  neurological disorder  |  10
C0031572  |  social phobia  |  10
C0006012  |  borderline personality disorder  |  10
C0024141  |  systemic lupus erythematosus  |  10
C0021831  |  bowel disease  |  9
C0022116  |  ischemia  |  9
C0042075  |  urological disorders  |  9
C0027765  |  neurological disorders  |  9
C0270549  |  generalized anxiety disorder  |  9
C0021390  |  inflammatory bowel disease  |  9
C0041696  |  major depression  |  9
C0221074  |  postnatal depression  |  9
C0853193  |  bipolar i disorder  |  9
C0004936  |  mental disorders  |  9
C0032460  |  polycystic ovary  |  8
C0020456  |  hyperglycemia  |  8
C0037315  |  sleep apnea  |  8
C0520679  |  obstructive sleep apnea  |  8
C0162429  |  malnutrition  |  8
C0020676  |  hypothyroidism  |  8
C0235974  |  pancreatic cancer  |  8
C0013473  |  eating disorders  |  8
C0002395  |  alzheimer disease  |  8
C0023895  |  liver disease  |  8
C0032460  |  polycystic ovary syndrome  |  8
C0007113  |  rectal cancer  |  7
C0017601  |  glaucoma  |  7
C0022661  |  end-stage renal disease  |  7
C0016053  |  fibromyalgia syndrome  |  7
C0028754  |  adiposity  |  7
C0409974  |  lupus erythematosus  |  7
C0001622  |  hypercortisolism  |  7
C0013395  |  dyspepsia  |  7
C0004352  |  autism  |  7
C0009402  |  colorectal cancer  |  7
C0002871  |  anemia  |  6
C0013415  |  dysthymia  |  6
C0851578  |  sleep disorders  |  6
C0042373  |  vascular diseases  |  6
C0039730  |  thalassemia  |  6
C0022104  |  irritable bowel syndrome  |  6
C0021359  |  infertile  |  6
C0022104  |  irritable bowel  |  6
C0028768  |  obsessive-compulsive disorder  |  6
C0029456  |  osteoporosis  |  6
C0027051  |  myocardial infarction (mi)  |  5
C0154437  |  atypical depression  |  5
C0524851  |  neurodegenerative disease  |  5
C0002736  |  amyotrophic lateral sclerosis  |  5
C0038436  |  posttraumatic stress disorder  |  5
C0155626  |  acute myocardial infarction  |  5
C0011854  |  type 1 diabetes mellitus  |  5
C0002871  |  anaemia  |  5
C0040188  |  tic disorders  |  5
C0024437  |  age-related macular degeneration  |  4
C0019196  |  hepatitis c infection  |  4
C0042870  |  vitamin d defic  |  4
C0221074  |  postpartum depression  |  4
C0007222  |  cardiovascular diseases  |  4
C0442874  |  neuropathy  |  4
C0035078  |  renal failure  |  4
C0598639  |  hypercortisolemia  |  4
C0006267  |  bronchiectasis  |  4
C0015674  |  chronic fatigue syndrome  |  4
C0011991  |  diarrhea  |  4
C0242350  |  erectile dysfunction  |  4
C0023646  |  lichen planus  |  4
C0022661  |  chronic renal failure  |  4
C0038013  |  ankylosing spondylitis  |  4
C0011860  |  type ii diabetes  |  4
C0000786  |  miscarriage  |  4
C0039494  |  temporomandibular disorder  |  4
C0010068  |  coronary disease  |  4
C0042870  |  vitamin d deficiency  |  4
C0022658  |  renal disease  |  4
C0042900  |  vitiligo  |  4
C0041296  |  tuberculosis  |  4
C0524851  |  neurodegenerative diseases  |  4
C0010674  |  cystic fibrosis  |  4
C0036202  |  sarcoidosis  |  4
C0032285  |  pneumonia  |  4
C0007570  |  celiac disease  |  4
C0029408  |  osteoarthritis  |  4
C0011269  |  vascular dementia  |  3
C0001144  |  acne vulgaris  |  3
C0149925  |  small cell lung cancer  |  3
C0001973  |  alcoholism  |  3
C0017178  |  gastrointestinal disorders  |  3
C0235974  |  pancreatic carcinoma  |  3
C0009319  |  colitis  |  3
C0035204  |  respiratory disease  |  3
C0018799  |  cardiac diseases  |  3
C0017168  |  esophageal reflux disease  |  3
C0014553  |  absence epilepsy  |  3
C0013421  |  dystonia  |  3
C0456909  |  vision loss  |  3
C0878544  |  cardiomyopathy  |  3
C0036337  |  schizoaffective disorder  |  3
C0033975  |  psychotic disorder  |  3
C0019163  |  hepatitis b  |  3
C0017168  |  gastroesophageal reflux disease  |  3
C0017168  |  oesophageal reflux  |  3
C0039494  |  temporomandibular disorders  |  3
C0033975  |  psychotic disorders  |  3
C0017168  |  gastroesophageal reflux  |  3
C0017178  |  gastrointestinal disorder  |  3
C0020598  |  hypoglycemia  |  3
C0149931  |  migraines  |  3
C0017168  |  esophageal reflux  |  3
C0036421  |  systemic sclerosis  |  3
C0004153  |  atherosclerosis  |  3
C0235250  |  hyperemesis  |  3
C0024437  |  macular degeneration  |  3
C0149654  |  conduct disorder  |  3
C0003872  |  psoriatic arthritis  |  3
C0006625  |  cachexia  |  3
C0009324  |  ulcerative colitis  |  3
C0020450  |  hyperemesis gravidarum  |  3
C0016470  |  food hypersensitivity  |  3
C0038436  |  post-traumatic stress disorder  |  3
C0030567  |  idiopathic parkinson's disease  |  3
C0007131  |  non-small cell lung cancer  |  3
C0042373  |  vascular disorder  |  3
C0024115  |  lung disease  |  2
C0020550  |  hyperthyroidism  |  2
C0023895  |  liver diseases  |  2
C0039494  |  temporomandibular joint disorder  |  2
C0042769  |  viral infection  |  2
C0002986  |  fabry disease  |  2
C0022658  |  nephropathy  |  2
C0314719  |  dry eye  |  2
C0002395  |  alzheimer's dementia  |  2
C0162836  |  hidradenitis suppurativa  |  2
C0024899  |  mastocytosis  |  2
C0027765  |  neurologic disorder  |  2
C0007131  |  nsclc  |  2
C0006384  |  bundle branch block  |  2
C0086543  |  cataract  |  2
C0085207  |  gestational diabetes  |  2
C1140680  |  ovarian ca  |  2
C0011860  |  diabetes mellitus type 2  |  2
C0026850  |  muscular dystrophy  |  2
C0011991  |  diarrhoea  |  2
C0010346  |  crohn disease  |  2
C0020456  |  hyperglycaemia  |  2
C0004352  |  autistic disorder  |  2
C0042165  |  anterior uveitis  |  2
C0040128  |  thyroid disorders  |  2
C0038012  |  spondylitis  |  2
C0152020  |  gastroparesis  |  2
C1140680  |  ovarian cancer  |  2
C0004134  |  ataxia  |  2
C0023890  |  liver cirrhosis  |  2
C0598608  |  hyperhomocysteinemia  |  2
C0020542  |  pulmonary hypertension  |  2
C0041341  |  tuberous sclerosis  |  2
C0042109  |  urticaria  |  2
C0041341  |  tuberous sclerosis complex  |  2
C1619734  |  pulmonary arterial hypertension  |  2
C0001430  |  adenoma  |  2
C0020619  |  hypogonadism  |  2
C0152021  |  congenital heart disease  |  2
C1261473  |  sarcoma  |  2
C0020179  |  huntington disease  |  2
C0035435  |  rheumatic diseases  |  2
C0282488  |  interstitial cystitis  |  2
C0154723  |  migraine with aura  |  2
C0010692  |  cystitis  |  2
C0013395  |  indigestion  |  2
C0037650  |  somatoform disorder  |  2
C0036323  |  schistosomiasis  |  2
C0031099  |  periodontitis  |  2
C0042373  |  vascular disorders  |  2
C0037116  |  silicosis  |  2
C0021053  |  immune disease  |  2
C0014547  |  focal epilepsy  |  2
C0007785  |  cerebral ischemia  |  2
C0041696  |  unipolar depression  |  2
C0162429  |  poor nutrition  |  2
C0035334  |  retinitis pigmentosa  |  2
C0021400  |  influenza  |  2
C0042769  |  virus infection  |  2
C0040147  |  thyroiditis  |  2
C0206062  |  interstitial lung disease  |  2
C0027765  |  neurologic disorders  |  2
C0024623  |  gastric cancer  |  2
C0003537  |  aphasia  |  2
C0014130  |  endocrine disturbance  |  2
C0018802  |  congestive heart failure  |  2
C0002874  |  aplastic anemia  |  2
C0011603  |  dermatitis  |  2
C0027932  |  neurosis  |  2
C0006870  |  cannabis dependence  |  2
C0752347  |  lewy body dementia  |  2
C0030305  |  pancreatitis  |  2
C0042164  |  uveitis  |  2
C0003125  |  anorexia nervosa  |  2
C0035333  |  retinitis  |  2
C0002895  |  sickle cell disease  |  2
C0006277  |  bronchitis  |  2
C0154723  |  migraine aura  |  2
C0011860  |  type ii diabetes mellitus  |  2
C0003850  |  arteriosclerosis  |  2
C0027873  |  neuromyelitis optica  |  2
C0032914  |  preeclampsia  |  2
C0013990  |  emphysema  |  2
C0001818  |  agoraphobia  |  2
C0028768  |  obsessive compulsive disorder  |  2
C0033581  |  prostatitis  |  2
C1510472  |  drug addiction  |  2
C0149521  |  chronic pancreatitis  |  2
C0023418  |  leukemia  |  2
C0037650  |  somatoform disorders  |  2
C0035435  |  rheumatic disease  |  2
C0002170  |  alopecia  |  2
C0025193  |  melancholia  |  2
C0085160  |  hidradenitis  |  2
C0042594  |  vestibular disease  |  1
C0025048  |  meconium aspiration  |  1
C0005741  |  blepharitis  |  1
C0034063  |  pulmonary edema  |  1
C0039494  |  temporomandibular joint disorders  |  1
C0012236  |  chromosome 22q11.2 deletion syndrome  |  1
C0011615  |  atopic dermatitis  |  1
C0037274  |  dermatological disorder  |  1
C0042769  |  viral infections  |  1
C0031090  |  periodontal diseases  |  1
C0037274  |  skin conditions  |  1
C0022661  |  chronic renal disease  |  1
C0023343  |  leprosy  |  1
C0025268  |  multiple endocrine neoplasia type ii  |  1
C0031090  |  periodontal disease  |  1
C0002395  |  alzheimer dementia  |  1
C0004943  |  behcet's disease  |  1
C0025303  |  meningococcal disease  |  1
C0042345  |  varicose vein  |  1
C0019360  |  herpes zoster  |  1
C0006145  |  breast disease  |  1
C0008495  |  chorioamnionitis  |  1
C0011884  |  diabetic retinopathy  |  1
C0033038  |  premature ejaculation  |  1
C0013884  |  lymphatic filariasis  |  1
C0004623  |  bacterial infections  |  1
C0022408  |  arthropathy  |  1
C0751967  |  relapsing-remitting multiple sclerosis  |  1
C0011303  |  demyelinating disorders  |  1
C0031069  |  familial mediterranean fever  |  1
C0018213  |  graves' disease  |  1
C0019337  |  heroin dependence  |  1
C0085413  |  autosomal dominant polycystic kidney disease  |  1
C0013720  |  ehlers-danlos syndrome  |  1
C0035258  |  restless legs syndrome (rls)  |  1
C0025267  |  multiple endocrine neoplasia type i  |  1
C0027765  |  nervous system disease  |  1
C0038363  |  aphthous stomatitis  |  1
C0010054  |  coronary atherosclerosis  |  1
C0016719  |  friedreich's ataxia  |  1
C0031485  |  phenylketonuria  |  1
C0022408  |  articular disease  |  1
C0021122  |  impulse control disorders  |  1
C0019829  |  hodgkin's lymphoma  |  1
C0040553  |  toxocara infection  |  1
C0014553  |  childhood absence epilepsy  |  1
C0030783  |  pellagra  |  1
C0743332  |  focal dystonia  |  1
C0009806  |  constipated  |  1
C0035579  |  hypovitaminosis d  |  1
C0684249  |  carcinoma of the lung  |  1
C0037315  |  sleep disordered breathing  |  1
C0037315  |  sleep apnea syndrome  |  1
C1142166  |  brugada syndrome  |  1
C0035258  |  restless legs  |  1
C0085615  |  right bundle branch block  |  1
C0085413  |  autosomal dominant polycystic kidney  |  1
C0701807  |  acute anterior uveitis  |  1
C0020179  |  huntington's disease  |  1
C0007282  |  carotid artery stenosis  |  1
C0013595  |  eczema  |  1
C0023530  |  leucopenia  |  1
C0040553  |  toxocariasis  |  1
C0032000  |  pituitary adenoma  |  1
C0020676  |  hypothyroid  |  1
C0006325  |  bruxism  |  1
C0042721  |  viral hepatitis  |  1
C0949690  |  spondyloarthritis  |  1
C0085436  |  cryptococcal meningitis  |  1
C0029121  |  oppositional defiant disorder  |  1
C0553662  |  juvenile ra  |  1
C0026636  |  oral disease  |  1
C0338480  |  migraine without aura  |  1
C0016412  |  folate deficiency  |  1
C0015230  |  rash  |  1
C0002888  |  megaloblastic anemia  |  1
C0524851  |  neurodegenerative disorders  |  1
C0032371  |  polio  |  1
C0085404  |  poems syndrome  |  1
C0339204  |  staphyloma  |  1
C0015310  |  exotropia  |  1
C0003864  |  inflammatory arthritis  |  1
C0041327  |  pulmonary tuberculosis  |  1
C0683416  |  depersonalization disorder  |  1
C0392525  |  nephrolithiasis  |  1
C0085220  |  cerebral amyloid angiopathy  |  1
C0270736  |  essential tremor  |  1
C0010346  |  crohn's disease  |  1
C0311223  |  frozen shoulder  |  1
C0271650  |  prediabetes  |  1
C0006430  |  burning mouth syndrome  |  1
C0006370  |  bulimia  |  1
C0566602  |  primary sclerosing cholangitis  |  1
C0699790  |  colon carcinoma  |  1
C0152025  |  polyneuropathy  |  1
C0011334  |  dental caries  |  1
C0678222  |  breast cancer diagnosis  |  1
C0271623  |  secondary hypogonadism  |  1
C0004623  |  bacterial infection  |  1
C0038220  |  status epilepticus  |  1
C0008350  |  cholelithiasis  |  1
C0920350  |  autoimmune thyroiditis  |  1
C0032357  |  poland's syndrome  |  1
C0019204  |  hepatocellular carcinoma  |  1
C0085113  |  neurofibromatosis  |  1
C0024299  |  lymphoma  |  1
C0004245  |  atrioventricular block  |  1
C0035204  |  respiratory diseases  |  1
C0014544  |  epilepsies  |  1
C0019348  |  herpes simplex  |  1
C0040425  |  tonsillitis  |  1
C0029124  |  optic atrophy  |  1
C0011334  |  cavities  |  1
C0008311  |  cholangitis  |  1
C0227791  |  vaginal discharge  |  1
C0003851  |  arteriosclerosis obliterans  |  1
C0025281  |  meniere's disease  |  1
C0031117  |  peripheral neuropathy  |  1
C0085669  |  acute leukemia  |  1
C0013384  |  dyskinesia  |  1
C0037274  |  dermatoses  |  1
C0031106  |  aggressive periodontitis  |  1
C0038868  |  progressive supranuclear palsy  |  1
C0001206  |  acromegaly  |  1
C0038379  |  strabismus  |  1
C0497327  |  dementias  |  1
C0014038  |  brain inflammation  |  1
C0007766  |  cranial aneurysm  |  1
C0042075  |  urological diseases  |  1
C0020538  |  increased blood pressure  |  1
C0025269  |  multiple endocrine neoplasia type iib  |  1
C0025306  |  meningococcal sepsis  |  1
C0007194  |  hypertrophic cardiomyopathy  |  1
C0022336  |  creutzfeldt-jakob disease  |  1
C1333990  |  lynch syndrome  |  1
C0751265  |  learning disabilities  |  1
C0085655  |  polymyositis  |  1
C0029095  |  opioid abuse  |  1
C0009806  |  constipation  |  1
C0030662  |  compulsive gambling  |  1
C0028756  |  morbid obesity  |  1
C0026846  |  muscle atrophy  |  1
C0162820  |  allergic contact dermatitis  |  1
C0035309  |  retinopathy  |  1
C0025048  |  meconium aspiration syndrome  |  1
C0042847  |  vitamin b12 defic  |  1
C0339143  |  graves' ophthalmopathy  |  1
C0162531  |  hereditary coproporphyria  |  1
C0032002  |  pituitary disorders  |  1
C1510472  |  drug dependence  |  1
C0032000  |  pituitary adenomas  |  1
C1800706  |  idiopathic pulmonary fibrosis  |  1
C0011334  |  caries  |  1
C0752347  |  lewy body disease  |  1
C0037315  |  sleep-disordered breathing  |  1
C0001529  |  dercum's disease  |  1
C0011881  |  diabetic nephropathy  |  1
C0027404  |  narcolepsy  |  1
C0025362  |  mental retardation  |  1
C0751955  |  brain infarct  |  1
C0752347  |  dementia with lewy bodies  |  1
C0032460  |  polycystic ovarian syndrome  |  1
C0349604  |  intracranial meningioma  |  1
C0024312  |  lymphopenia  |  1
C0003431  |  antisocial personality disorder  |  1
C0376685  |  subacromial impingement syndrome  |  1
C0013264  |  duchenne muscular dystrophy  |  1
C0220650  |  brain metastases  |  1
C0006111  |  brain disease  |  1
C0019243  |  hereditary angioedema  |  1
C0024115  |  lung diseases  |  1
C0021670  |  insulinoma  |  1
C0023890  |  cirrhosis  |  1
C0007222  |  cardiovascular disorders  |  1
C0039590  |  testicular cancer  |  1
C0020604  |  hypochondriasis  |  1
C0039263  |  takayasu's arteritis  |  1
C0035372  |  rett syndrome  |  1
C0151744  |  myocardial ischemia  |  1
C0017152  |  gastritis  |  1
C0036439  |  scoliosis  |  1
C0023234  |  perthes disease  |  1
C1720771  |  hydrocele  |  1
C0038358  |  gastric ulcer  |  1
C0025289  |  meningitis  |  1
C0020502  |  hyperparathyroidism  |  1
C0042345  |  varicose veins  |  1
C0034069  |  pulmonary fibrosis  |  1
C0271650  |  glucose intolerance  |  1
C0028817  |  ochronosis  |  1
C0007682  |  diseases of the central nervous system  |  1
C0349604  |  intracranial meningiomas  |  1
C0006023  |  borna disease  |  1
C0024115  |  lung disorders  |  1
C0221002  |  primary hyperparathyroidism  |  1
C0012236  |  22q11.2 deletion syndrome  |  1
C0015397  |  eye disease  |  1
C0005283  |  beta thalassemia  |  1
C0241910  |  autoimmune hepatitis  |  1
C0038362  |  stomatitis  |  1
C1261473  |  soft tissue sarcoma  |  1
C0162316  |  iron deficiency anemia  |  1
C0023903  |  liver cancer  |  1
C0031212  |  personality disorders  |  1
C0221765  |  chronic schizophrenia  |  1
C0035854  |  rosacea  |  1
C0040128  |  thyroid disease  |  1
C1257763  |  overnutrition  |  1
C0035258  |  restless legs syndrome  |  1
C1510471  |  hypovitaminosis  |  1
C1561644  |  chronic kidney disease (ckd)  |  1
C0018799  |  heart diseases  |  1
C0027662  |  multiple endocrine neoplasia  |  1
C0011616  |  contact dermatitis  |  1
C0030312  |  pancytopenia  |  1
C0012569  |  diplopia  |  1
C0520679  |  obstructive sleep apnea syndrome  |  1
C0085207  |  gestational diabetes mellitus  |  1
C0013238  |  dry eye syndrome  |  1
C0008313  |  sclerosing cholangitis  |  1
C0004943  |  behcet's syndrome  |  1
C0034065  |  pulmonary embolism  |  1
C0234507  |  anosognosia  |  1
C0004096  |  bronchial asthma  |  1
C0016085  |  filariasis  |  1
C1135191  |  systolic heart failure  |  1
C0007193  |  dilated cardiomyopathy  |  1
C0236792  |  asperger syndrome  |  1
C0042847  |  vitamin b12 deficiency  |  1
C0013264  |  duchenne muscular dystrophy (dmd)  |  1
C0007766  |  intracranial aneurysm  |  1
C0018799  |  cardiac disorders  |  1
C0027765  |  neurological disease  |  1
C0019829  |  hodgkin lymphoma  |  1
C0031190  |  persistent pulmonary hypertension of the newborn  |  1
C0040034  |  thrombocytopenia  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:1)
RORA  |  6095  |  GWASCAT
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:160)
15  |  AANAT  |  infer
5243  |  ABCB1  |  infer
28  |  ABO  |  infer
1636  |  ACE  |  infer
150  |  ADRA2A  |  infer
154  |  ADRB2  |  infer
183  |  AGT  |  infer
185  |  AGTR1  |  infer
186  |  AGTR2  |  infer
241  |  ALOX5AP  |  infer
338  |  APOB  |  infer
348  |  APOE  |  infer
367  |  AR  |  infer
55082  |  ARGLU1  |  infer
406  |  ARNTL  |  infer
56938  |  ARNTL2  |  infer
438  |  ASMT  |  infer
535  |  ATP6V0A1  |  infer
4287  |  ATXN3  |  infer
8313  |  AXIN2  |  infer
627  |  BDNF  |  infer
8553  |  BHLHE40  |  infer
79365  |  BHLHE41  |  infer
80114  |  BICC1  |  infer
775  |  CACNA1C  |  infer
916  |  CD3E  |  infer
1012  |  CDH13  |  infer
1015  |  CDH17  |  infer
1103  |  CHAT  |  infer
1129  |  CHRM2  |  infer
23122  |  CLASP2  |  infer
9575  |  CLOCK  |  infer
1268  |  CNR1  |  infer
1270  |  CNTF  |  infer
1312  |  COMT  |  infer
1385  |  CREB1  |  infer
1387  |  CREBBP  |  infer
1392  |  CRH  |  infer
1394  |  CRHR1  |  infer
1395  |  CRHR2  |  infer
1401  |  CRP  |  infer
1407  |  CRY1  |  infer
1408  |  CRY2  |  infer
1454  |  CSNK1E  |  infer
1493  |  CTLA4  |  infer
1544  |  CYP1A2  |  infer
1557  |  CYP2C19  |  infer
1559  |  CYP2C9  |  infer
1565  |  CYP2D6  |  infer
267012  |  DAOA  |  infer
1628  |  DBP  |  infer
79009  |  DDX50  |  infer
27185  |  DISC1  |  infer
1813  |  DRD2  |  infer
1814  |  DRD3  |  infer
1815  |  DRD4  |  infer
84062  |  DTNBP1  |  infer
1856  |  DVL2  |  infer
8665  |  EIF3F  |  infer
2018  |  EMX2  |  infer
2047  |  EPHB1  |  infer
2289  |  FKBP5  |  infer
7976  |  FZD3  |  infer
2571  |  GAD1  |  infer
2572  |  GAD2  |  infer
2778  |  GNAS  |  infer
2784  |  GNB3  |  infer
2892  |  GRIA3  |  infer
2917  |  GRM7  |  infer
2918  |  GRM8  |  infer
2932  |  GSK3B  |  infer
2944  |  GSTM1  |  infer
2952  |  GSTT1  |  infer
646273  |  HSPD1P15  |  infer
3350  |  HTR1A  |  infer
3351  |  HTR1B  |  infer
3356  |  HTR2A  |  infer
3358  |  HTR2C  |  infer
3359  |  HTR3A  |  infer
3362  |  HTR6  |  infer
3454  |  IFNAR1  |  infer
3553  |  IL1B  |  infer
3557  |  IL1RN  |  infer
3569  |  IL6  |  infer
3688  |  ITGB1  |  infer
3776  |  KCNK2  |  infer
51176  |  LEF1  |  infer
3952  |  LEP  |  infer
4049  |  LTA  |  infer
4048  |  LTA4H  |  infer
4128  |  MAOA  |  infer
4137  |  MAPT  |  infer
55784  |  MCTP2  |  infer
407034  |  MIR30E  |  infer
4522  |  MTHFD1  |  infer
4524  |  MTHFR  |  infer
4548  |  MTR  |  infer
53904  |  MYO3A  |  infer
23040  |  MYT1L  |  infer
4773  |  NFATC2  |  infer
4783  |  NFIL3  |  infer
22871  |  NLGN1  |  infer
4862  |  NPAS2  |  infer
4852  |  NPY  |  infer
9572  |  NR1D1  |  infer
2908  |  NR3C1  |  infer
3084  |  NRG1  |  infer
4915  |  NTRK2  |  infer
4916  |  NTRK3  |  infer
5021  |  OXTR  |  infer
5027  |  P2RX7  |  infer
50940  |  PDE11A  |  infer
5136  |  PDE1A  |  infer
5152  |  PDE9A  |  infer
10611  |  PDLIM5  |  infer
5187  |  PER1  |  infer
8864  |  PER2  |  infer
8863  |  PER3  |  infer
267007  |  PGBD3P3  |  infer
5321  |  PLA2G4A  |  infer
5444  |  PON1  |  infer
5468  |  PPARG  |  infer
5583  |  PRKCH  |  infer
5663  |  PSEN1  |  infer
5692  |  PSMB4  |  infer
5715  |  PSMD9  |  infer
5743  |  PTGS2  |  infer
10411  |  RAPGEF3  |  infer
56963  |  RGMA  |  infer
51458  |  RHCG  |  infer
6095  |  RORA  |  infer
6285  |  S100B  |  infer
5054  |  SERPINE1  |  infer
6529  |  SLC6A1  |  infer
6530  |  SLC6A2  |  infer
6531  |  SLC6A3  |  infer
6532  |  SLC6A4  |  infer
53919  |  SLCO1C1  |  infer
100506736  |  SLFN12L  |  infer
6648  |  SOD2  |  infer
6697  |  SPR  |  infer
6774  |  STAT3  |  infer
9899  |  SV2B  |  infer
30009  |  TBX21  |  infer
6925  |  TCF4  |  infer
7021  |  TFAP2B  |  infer
7040  |  TGFB1  |  infer
8914  |  TIMELESS  |  infer
7124  |  TNF  |  infer
7157  |  TP53  |  infer
7166  |  TPH1  |  infer
121278  |  TPH2  |  infer
7249  |  TSC2  |  infer
7257  |  TSNAX  |  infer
114131  |  UCN3  |  infer
26276  |  VPS33B  |  infer
7476  |  WNT7A  |  infer
7494  |  XBP1  |  infer
9839  |  ZEB2  |  infer
51738  |  GHRL  |  infer
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:598)
27184  |  DISC2  |  DISEASES
100126791  |  EGOT  |  DISEASES
1407  |  CRY1  |  DISEASES
5536  |  PPP5C  |  DISEASES
57554  |  LRRC7  |  DISEASES
2767  |  GNA11  |  DISEASES
4804  |  NGFR  |  DISEASES
1815  |  DRD4  |  DISEASES
9108  |  MTMR7  |  DISEASES
27248  |  ERLEC1  |  DISEASES
7384  |  UQCRC1  |  DISEASES
51291  |  GMIP  |  DISEASES
7023  |  TFAP4  |  DISEASES
25984  |  KRT23  |  DISEASES
4713  |  NDUFB7  |  DISEASES
4282  |  MIF  |  DISEASES
5816  |  PVALB  |  DISEASES
328  |  APEX1  |  DISEASES
10278  |  EFS  |  DISEASES
6729  |  SRP54  |  DISEASES
128674  |  PROKR2  |  DISEASES
5173  |  PDYN  |  DISEASES
5020  |  OXT  |  DISEASES
9248  |  GPR50  |  DISEASES
51090  |  PLLP  |  DISEASES
6530  |  SLC6A2  |  DISEASES
7038  |  TG  |  DISEASES
57030  |  SLC17A7  |  DISEASES
56729  |  RETN  |  DISEASES
6449  |  SGTA  |  DISEASES
6822  |  SULT2A1  |  DISEASES
5864  |  RAB3A  |  DISEASES
6347  |  CCL2  |  DISEASES
10014  |  HDAC5  |  DISEASES
3558  |  IL2  |  DISEASES
3458  |  IFNG  |  DISEASES
2784  |  GNB3  |  DISEASES
2026  |  ENO2  |  DISEASES
55907  |  CMAS  |  DISEASES
50856  |  CLEC4A  |  DISEASES
8683  |  SRSF9  |  DISEASES
9450  |  LY86  |  DISEASES
3003  |  GZMK  |  DISEASES
1007  |  CDH9  |  DISEASES
7265  |  TTC1  |  DISEASES
3565  |  IL4  |  DISEASES
3567  |  IL5  |  DISEASES
2908  |  NR3C1  |  DISEASES
11334  |  TUSC2  |  DISEASES
27136  |  MORC1  |  DISEASES
7781  |  SLC30A3  |  DISEASES
374291  |  NDUFS7  |  DISEASES
2691  |  GHRH  |  DISEASES
55640  |  FLVCR2  |  DISEASES
1843  |  DUSP1  |  DISEASES
1958  |  EGR1  |  DISEASES
7976  |  FZD3  |  DISEASES
5533  |  PPP3CC  |  DISEASES
8997  |  KALRN  |  DISEASES
4852  |  NPY  |  DISEASES
5153  |  PDE1B  |  DISEASES
206358  |  SLC36A1  |  DISEASES
29993  |  PACSIN1  |  DISEASES
4201  |  MEA1  |  DISEASES
2354  |  FOSB  |  DISEASES
83541  |  FAM110A  |  DISEASES
7389  |  UROD  |  DISEASES
9572  |  NR1D1  |  DISEASES
51657  |  STYXL1  |  DISEASES
2847  |  MCHR1  |  DISEASES
8484  |  GALR3  |  DISEASES
7425  |  VGF  |  DISEASES
7166  |  TPH1  |  DISEASES
6351  |  CCL4  |  DISEASES
3630  |  INS  |  DISEASES
348  |  APOE  |  DISEASES
10452  |  TOMM40  |  DISEASES
2670  |  GFAP  |  DISEASES
113  |  ADCY7  |  DISEASES
8864  |  PER2  |  DISEASES
51540  |  SCLY  |  DISEASES
6616  |  SNAP25  |  DISEASES
1401  |  CRP  |  DISEASES
1131  |  CHRM3  |  DISEASES
51124  |  IER3IP1  |  DISEASES
9695  |  EDEM1  |  DISEASES
3357  |  HTR2B  |  DISEASES
1329  |  COX5B  |  DISEASES
3569  |  IL6  |  DISEASES
2572  |  GAD2  |  DISEASES
1208  |  CLPS  |  DISEASES
109  |  ADCY3  |  DISEASES
1559  |  CYP2C9  |  DISEASES
9360  |  PPIG  |  DISEASES
55729  |  ATF7IP  |  DISEASES
6095  |  RORA  |  DISEASES
6532  |  SLC6A4  |  DISEASES
23531  |  MMD  |  DISEASES
6505  |  SLC1A1  |  DISEASES
4969  |  OGN  |  DISEASES
25939  |  SAMHD1  |  DISEASES
2769  |  GNA15  |  DISEASES
10998  |  SLC27A5  |  DISEASES
2033  |  EP300  |  DISEASES
3553  |  IL1B  |  DISEASES
57731  |  SPTBN4  |  DISEASES
5033  |  P4HA1  |  DISEASES
6403  |  SELP  |  DISEASES
54431  |  DNAJC10  |  DISEASES
56925  |  LXN  |  DISEASES
2557  |  GABRA4  |  DISEASES
7531  |  YWHAE  |  DISEASES
2892  |  GRIA3  |  DISEASES
2891  |  GRIA2  |  DISEASES
1008  |  CDH10  |  DISEASES
2247  |  FGF2  |  DISEASES
5443  |  POMC  |  DISEASES
55300  |  PI4K2B  |  DISEASES
64083  |  GOLPH3  |  DISEASES
6507  |  SLC1A3  |  DISEASES
64374  |  SIL1  |  DISEASES
2568  |  GABRP  |  DISEASES
10058  |  ABCB6  |  DISEASES
1390  |  CREM  |  DISEASES
793  |  CALB1  |  DISEASES
54806  |  AHI1  |  DISEASES
51083  |  GAL  |  DISEASES
5243  |  ABCB1  |  DISEASES
55749  |  CCAR1  |  DISEASES
53904  |  MYO3A  |  DISEASES
55830  |  GLT8D1  |  DISEASES
23598  |  PATZ1  |  DISEASES
7008  |  TEF  |  DISEASES
775  |  CACNA1C  |  DISEASES
55117  |  SLC6A15  |  DISEASES
1583  |  CYP11A1  |  DISEASES
4240  |  MFGE8  |  DISEASES
374655  |  ZNF710  |  DISEASES
4355  |  MPP2  |  DISEASES
207  |  AKT1  |  DISEASES
6531  |  SLC6A3  |  DISEASES
5141  |  PDE4A  |  DISEASES
149111  |  CNIH3  |  DISEASES
3697  |  ITIH1  |  DISEASES
89876  |  MAATS1  |  DISEASES
6988  |  TCTA  |  DISEASES
170690  |  ADAMTS16  |  DISEASES
1404  |  HAPLN1  |  DISEASES
1393  |  CRHBP  |  DISEASES
2559  |  GABRA6  |  DISEASES
3358  |  HTR2C  |  DISEASES
139818  |  DOCK11  |  DISEASES
526  |  ATP6V1B2  |  DISEASES
11160  |  ERLIN2  |  DISEASES
1392  |  CRH  |  DISEASES
3439  |  IFNA1  |  DISEASES
10280  |  SIGMAR1  |  DISEASES
4915  |  NTRK2  |  DISEASES
5047  |  PAEP  |  DISEASES
6506  |  SLC1A2  |  DISEASES
9415  |  FADS2  |  DISEASES
2904  |  GRIN2B  |  DISEASES
150  |  ADRA2A  |  DISEASES
3606  |  IL18  |  DISEASES
288  |  ANK3  |  DISEASES
4931  |  NVL  |  DISEASES
2893  |  GRIA4  |  DISEASES
2911  |  GRM1  |  DISEASES
5801  |  PTPRR  |  DISEASES
4900  |  NRGN  |  DISEASES
25890  |  ABI3BP  |  DISEASES
2890  |  GRIA1  |  DISEASES
50940  |  PDE11A  |  DISEASES
2776  |  GNAQ  |  DISEASES
7381  |  UQCRB  |  DISEASES
6156  |  RPL30  |  DISEASES
6750  |  SST  |  DISEASES
3361  |  HTR5A  |  DISEASES
3362  |  HTR6  |  DISEASES
5692  |  PSMB4  |  DISEASES
1636  |  ACE  |  DISEASES
808  |  CALM3  |  DISEASES
5152  |  PDE9A  |  DISEASES
6285  |  S100B  |  DISEASES
6271  |  S100A1  |  DISEASES
3060  |  HCRT  |  DISEASES
1742  |  DLG4  |  DISEASES
115  |  ADCY9  |  DISEASES
60675  |  PROK2  |  DISEASES
152185  |  SPICE1  |  DISEASES
213  |  ALB  |  DISEASES
4724  |  NDUFS4  |  DISEASES
134265  |  AFAP1L1  |  DISEASES
9607  |  CARTPT  |  DISEASES
107  |  ADCY1  |  DISEASES
145581  |  LRFN5  |  DISEASES
6571  |  SLC18A2  |  DISEASES
282974  |  STK32C  |  DISEASES
29986  |  SLC39A2  |  DISEASES
144568  |  A2ML1  |  DISEASES
2587  |  GALR1  |  DISEASES
6632  |  SNRPD1  |  DISEASES
51704  |  GPRC5B  |  DISEASES
762  |  CA4  |  DISEASES
121274  |  ZNF641  |  DISEASES
4054  |  LTBP3  |  DISEASES
5368  |  PNOC  |  DISEASES
5617  |  PRL  |  DISEASES
6356  |  CCL11  |  DISEASES
3479  |  IGF1  |  DISEASES
4543  |  MTNR1A  |  DISEASES
140738  |  TMEM37  |  DISEASES
91752  |  ZNF804A  |  DISEASES
7200  |  TRH  |  DISEASES
6869  |  TACR1  |  DISEASES
6249  |  CLIP1  |  DISEASES
3596  |  IL13  |  DISEASES
340024  |  SLC6A19  |  DISEASES
2915  |  GRM5  |  DISEASES
2353  |  FOS  |  DISEASES
1128  |  CHRM1  |  DISEASES
255239  |  ANKK1  |  DISEASES
8462  |  KLF11  |  DISEASES
123099  |  DEGS2  |  DISEASES
112464  |  PRKCDBP  |  DISEASES
54541  |  DDIT4  |  DISEASES
794  |  CALB2  |  DISEASES
10098  |  TSPAN5  |  DISEASES
152189  |  CMTM8  |  DISEASES
2752  |  GLUL  |  DISEASES
1938  |  EEF2  |  DISEASES
9575  |  CLOCK  |  DISEASES
9986  |  RCE1  |  DISEASES
7534  |  YWHAZ  |  DISEASES
8609  |  KLF7  |  DISEASES
7634  |  ZNF80  |  DISEASES
92126  |  DSEL  |  DISEASES
119765  |  OR4B1  |  DISEASES
7368  |  UGT8  |  DISEASES
148014  |  TTC9B  |  DISEASES
54221  |  SNTG2  |  DISEASES
54674  |  LRRN3  |  DISEASES
8557  |  TCAP  |  DISEASES
50809  |  HP1BP3  |  DISEASES
3952  |  LEP  |  DISEASES
54862  |  CC2D1A  |  DISEASES
23  |  ABCF1  |  DISEASES
3352  |  HTR1D  |  DISEASES
113026  |  PLCD3  |  DISEASES
116138  |  KLHDC3  |  DISEASES
6844  |  VAMP2  |  DISEASES
55588  |  MED29  |  DISEASES
2907  |  GRINA  |  DISEASES
1831  |  TSC22D3  |  DISEASES
1191  |  CLU  |  DISEASES
4728  |  NDUFS8  |  DISEASES
3350  |  HTR1A  |  DISEASES
9229  |  DLGAP1  |  DISEASES
8560  |  DEGS1  |  DISEASES
10170  |  DHRS9  |  DISEASES
3291  |  HSD11B2  |  DISEASES
115207  |  KCTD12  |  DISEASES
28959  |  TMEM176B  |  DISEASES
56952  |  PRTFDC1  |  DISEASES
8630  |  HSD17B6  |  DISEASES
377677  |  CA13  |  DISEASES
818  |  CAMK2G  |  DISEASES
1005  |  CDH7  |  DISEASES
83787  |  ARMC10  |  DISEASES
80256  |  FAM214B  |  DISEASES
1129  |  CHRM2  |  DISEASES
783  |  CACNB2  |  DISEASES
9520  |  NPEPPS  |  DISEASES
28232  |  SLCO3A1  |  DISEASES
9370  |  ADIPOQ  |  DISEASES
6863  |  TAC1  |  DISEASES
23539  |  SLC16A8  |  DISEASES
10611  |  PDLIM5  |  DISEASES
6817  |  SULT1A1  |  DISEASES
84938  |  ATG4C  |  DISEASES
3992  |  FADS1  |  DISEASES
170572  |  HTR3C  |  DISEASES
1879  |  EBF1  |  DISEASES
3355  |  HTR1F  |  DISEASES
284273  |  ZADH2  |  DISEASES
3309  |  HSPA5  |  DISEASES
5021  |  OXTR  |  DISEASES
112885  |  PHF21B  |  DISEASES
1555  |  CYP2B6  |  DISEASES
2932  |  GSK3B  |  DISEASES
57010  |  CABP4  |  DISEASES
30845  |  EHD3  |  DISEASES
1812  |  DRD1  |  DISEASES
5074  |  PAWR  |  DISEASES
63891  |  RNF123  |  DISEASES
8905  |  AP1S2  |  DISEASES
706  |  TSPO  |  DISEASES
9501  |  RPH3AL  |  DISEASES
121278  |  TPH2  |  DISEASES
596  |  BCL2  |  DISEASES
527  |  ATP6V0C  |  DISEASES
2894  |  GRID1  |  DISEASES
8224  |  SYN3  |  DISEASES
8330  |  HIST1H2AK  |  DISEASES
277  |  AMY1B  |  DISEASES
7850  |  IL1R2  |  DISEASES
10215  |  OLIG2  |  DISEASES
5136  |  PDE1A  |  DISEASES
64782  |  AEN  |  DISEASES
5142  |  PDE4B  |  DISEASES
222546  |  RFX6  |  DISEASES
2903  |  GRIN2A  |  DISEASES
4887  |  NPY2R  |  DISEASES
9899  |  SV2B  |  DISEASES
166752  |  FREM3  |  DISEASES
348235  |  SKA2  |  DISEASES
55137  |  FIGN  |  DISEASES
496  |  ATP4B  |  DISEASES
27445  |  PCLO  |  DISEASES
245908  |  DEFB105A  |  DISEASES
9456  |  HOMER1  |  DISEASES
54997  |  TESC  |  DISEASES
5138  |  PDE2A  |  DISEASES
51738  |  GHRL  |  DISEASES
504180  |  DEFB105B  |  DISEASES
285242  |  HTR3E  |  DISEASES
885  |  CCK  |  DISEASES
5025  |  P2RX4  |  DISEASES
3988  |  LIPA  |  DISEASES
114548  |  NLRP3  |  DISEASES
64359  |  NXN  |  DISEASES
4842  |  NOS1  |  DISEASES
160851  |  DGKH  |  DISEASES
1641  |  DCX  |  DISEASES
57142  |  RTN4  |  DISEASES
1576  |  CYP3A4  |  DISEASES
3363  |  HTR7  |  DISEASES
2289  |  FKBP5  |  DISEASES
23236  |  PLCB1  |  DISEASES
4862  |  NPAS2  |  DISEASES
23583  |  SMUG1  |  DISEASES
90627  |  STARD13  |  DISEASES
9402  |  GRAP2  |  DISEASES
22978  |  NT5C2  |  DISEASES
6251  |  RSU1  |  DISEASES
158062  |  LCN6  |  DISEASES
817  |  CAMK2D  |  DISEASES
4076  |  CAPRIN1  |  DISEASES
6609  |  SMPD1  |  DISEASES
4128  |  MAOA  |  DISEASES
284695  |  ZNF326  |  DISEASES
4137  |  MAPT  |  DISEASES
1395  |  CRHR2  |  DISEASES
4306  |  NR3C2  |  DISEASES
80778  |  ZNF34  |  DISEASES
84062  |  DTNBP1  |  DISEASES
132660  |  LIN54  |  DISEASES
1544  |  CYP1A2  |  DISEASES
866  |  SERPINA6  |  DISEASES
100134938  |  UPK3BL  |  DISEASES
108  |  ADCY2  |  DISEASES
124454  |  EARS2  |  DISEASES
9771  |  RAPGEF5  |  DISEASES
2100  |  ESR2  |  DISEASES
2918  |  GRM8  |  DISEASES
3605  |  IL17A  |  DISEASES
4929  |  NR4A2  |  DISEASES
84969  |  TOX2  |  DISEASES
10617  |  STAMBP  |  DISEASES
89932  |  PAPLN  |  DISEASES
2879  |  GPX4  |  DISEASES
10307  |  APBB3  |  DISEASES
6050  |  RNH1  |  DISEASES
50618  |  ITSN2  |  DISEASES
3359  |  HTR3A  |  DISEASES
8871  |  SYNJ2  |  DISEASES
9260  |  PDLIM7  |  DISEASES
3240  |  HP  |  DISEASES
23154  |  NCDN  |  DISEASES
64067  |  NPAS3  |  DISEASES
137902  |  PXDNL  |  DISEASES
3084  |  NRG1  |  DISEASES
53916  |  RAB4B  |  DISEASES
8332  |  HIST1H2AL  |  DISEASES
65989  |  DLK2  |  DISEASES
2917  |  GRM7  |  DISEASES
55784  |  MCTP2  |  DISEASES
29950  |  SERTAD1  |  DISEASES
2571  |  GAD1  |  DISEASES
26136  |  TES  |  DISEASES
8329  |  HIST1H2AI  |  DISEASES
8969  |  HIST1H2AG  |  DISEASES
8936  |  WASF1  |  DISEASES
5116  |  PCNT  |  DISEASES
8336  |  HIST1H2AM  |  DISEASES
1454  |  CSNK1E  |  DISEASES
79947  |  DHDDS  |  DISEASES
386617  |  KCTD8  |  DISEASES
83666  |  PARP9  |  DISEASES
1565  |  CYP2D6  |  DISEASES
104  |  ADARB1  |  DISEASES
4916  |  NTRK3  |  DISEASES
8532  |  CPZ  |  DISEASES
1745  |  DLX1  |  DISEASES
1312  |  COMT  |  DISEASES
4860  |  PNP  |  DISEASES
2475  |  MTOR  |  DISEASES
1813  |  DRD2  |  DISEASES
148753  |  FAM163A  |  DISEASES
51603  |  METTL13  |  DISEASES
388677  |  NOTCH2NL  |  DISEASES
8863  |  PER3  |  DISEASES
56259  |  CTNNBL1  |  DISEASES
56853  |  CELF4  |  DISEASES
116443  |  GRIN3A  |  DISEASES
2913  |  GRM3  |  DISEASES
8564  |  KMO  |  DISEASES
27185  |  DISC1  |  DISEASES
7257  |  TSNAX  |  DISEASES
343035  |  RD3  |  DISEASES
9641  |  IKBKE  |  DISEASES
553  |  AVPR1B  |  DISEASES
64710  |  NUCKS1  |  DISEASES
23345  |  SYNE1  |  DISEASES
127833  |  SYT2  |  DISEASES
51278  |  IER5  |  DISEASES
2328  |  FMO3  |  DISEASES
6446  |  SGK1  |  DISEASES
8417  |  STX7  |  DISEASES
5824  |  PEX19  |  DISEASES
4082  |  MARCKS  |  DISEASES
6281  |  S100A10  |  DISEASES
64077  |  LHPP  |  DISEASES
4803  |  NGF  |  DISEASES
1081  |  CGA  |  DISEASES
8517  |  IKBKG  |  DISEASES
2316  |  FLNA  |  DISEASES
54805  |  CNNM2  |  DISEASES
3351  |  HTR1B  |  DISEASES
278  |  AMY1C  |  DISEASES
276  |  AMY1A  |  DISEASES
23443  |  SLC35A3  |  DISEASES
1137  |  CHRNA4  |  DISEASES
55879  |  GABRQ  |  DISEASES
2556  |  GABRA3  |  DISEASES
115004  |  MB21D1  |  DISEASES
6319  |  SCD  |  DISEASES
2332  |  FMR1  |  DISEASES
4923  |  NTSR1  |  DISEASES
2258  |  FGF13  |  DISEASES
51557  |  LGSN  |  DISEASES
1557  |  CYP2C19  |  DISEASES
286257  |  C9orf142  |  DISEASES
94233  |  OPN4  |  DISEASES
2899  |  GRIK3  |  DISEASES
6812  |  STXBP1  |  DISEASES
4674  |  NAP1L2  |  DISEASES
3061  |  HCRTR1  |  DISEASES
2170  |  FABP3  |  DISEASES
6429  |  SRSF4  |  DISEASES
80114  |  BICC1  |  DISEASES
26190  |  FBXW2  |  DISEASES
2914  |  GRM4  |  DISEASES
2048  |  EPHB2  |  DISEASES
8518  |  IKBKAP  |  DISEASES
3055  |  HCK  |  DISEASES
267012  |  DAOA  |  DISEASES
1740  |  DLG2  |  DISEASES
56243  |  KIAA1217  |  DISEASES
4524  |  MTHFR  |  DISEASES
55312  |  RFK  |  DISEASES
6992  |  PPP1R11  |  DISEASES
6096  |  RORB  |  DISEASES
4340  |  MOG  |  DISEASES
128821  |  CST9L  |  DISEASES
1325  |  CORT  |  DISEASES
27253  |  PCDH17  |  DISEASES
4129  |  MAOB  |  DISEASES
2563  |  GABRD  |  DISEASES
3356  |  HTR2A  |  DISEASES
1855  |  DVL1  |  DISEASES
2625  |  GATA3  |  DISEASES
55676  |  SLC30A6  |  DISEASES
133482  |  SLCO6A1  |  DISEASES
551  |  AVP  |  DISEASES
8544  |  PIR  |  DISEASES
114131  |  UCN3  |  DISEASES
219402  |  MTIF3  |  DISEASES
7054  |  TH  |  DISEASES
438  |  ASMT  |  DISEASES
3709  |  ITPR2  |  DISEASES
7053  |  TGM3  |  DISEASES
10771  |  ZMYND11  |  DISEASES
51378  |  ANGPT4  |  DISEASES
5991  |  RFX3  |  DISEASES
137868  |  SGCZ  |  DISEASES
1010  |  CDH12  |  DISEASES
116448  |  OLIG1  |  DISEASES
2254  |  FGF9  |  DISEASES
10522  |  DEAF1  |  DISEASES
200909  |  HTR3D  |  DISEASES
361  |  AQP4  |  DISEASES
1814  |  DRD3  |  DISEASES
4336  |  MOBP  |  DISEASES
406  |  ARNTL  |  DISEASES
6710  |  SPTB  |  DISEASES
2524  |  FUT2  |  DISEASES
9244  |  CRLF1  |  DISEASES
10402  |  ST3GAL6  |  DISEASES
3426  |  CFI  |  DISEASES
2912  |  GRM2  |  DISEASES
83478  |  ARHGAP24  |  DISEASES
5137  |  PDE1C  |  DISEASES
64924  |  SLC30A5  |  DISEASES
594857  |  NPS  |  DISEASES
1394  |  CRHR1  |  DISEASES
344022  |  NOTO  |  DISEASES
54890  |  ALKBH5  |  DISEASES
29965  |  CDIP1  |  DISEASES
55536  |  CDCA7L  |  DISEASES
55112  |  WDR60  |  DISEASES
729920  |  ISPD  |  DISEASES
387804  |  VSTM5  |  DISEASES
501  |  ALDH7A1  |  DISEASES
9048  |  ARTN  |  DISEASES
1385  |  CREB1  |  DISEASES
348180  |  CTU2  |  DISEASES
79156  |  PLEKHF1  |  DISEASES
7726  |  TRIM26  |  DISEASES
57282  |  SLC4A10  |  DISEASES
146713  |  RBFOX3  |  DISEASES
2260  |  FGFR1  |  DISEASES
3113  |  HLA-DPA1  |  DISEASES
3776  |  KCNK2  |  DISEASES
4988  |  OPRM1  |  DISEASES
202333  |  CMYA5  |  DISEASES
146395  |  GSG1L  |  DISEASES
23040  |  MYT1L  |  DISEASES
10163  |  WASF2  |  DISEASES
5719  |  PSMD13  |  DISEASES
5999  |  RGS4  |  DISEASES
374868  |  ATP9B  |  DISEASES
7124  |  TNF  |  DISEASES
159371  |  SLC35G1  |  DISEASES
64084  |  CLSTN2  |  DISEASES
266727  |  MDGA1  |  DISEASES
2900  |  GRIK4  |  DISEASES
388372  |  CCL4L1  |  DISEASES
1408  |  CRY2  |  DISEASES
64943  |  NT5DC2  |  DISEASES
64854  |  USP46  |  DISEASES
80232  |  WDR26  |  DISEASES
121256  |  TMEM132D  |  DISEASES
2668  |  GDNF  |  DISEASES
9709  |  HERPUD1  |  DISEASES
154664  |  ABCA13  |  DISEASES
3586  |  IL10  |  DISEASES
627  |  BDNF  |  DISEASES
10046  |  MAMLD1  |  DISEASES
3699  |  ITIH3  |  DISEASES
135656  |  DPCR1  |  DISEASES
79813  |  EHMT1  |  DISEASES
79068  |  FTO  |  DISEASES
4045  |  LSAMP  |  DISEASES
111  |  ADCY5  |  DISEASES
51555  |  PEX5L  |  DISEASES
6949  |  TCOF1  |  DISEASES
56034  |  PDGFC  |  DISEASES
6196  |  RPS6KA2  |  DISEASES
84727  |  SPSB2  |  DISEASES
51312  |  SLC25A37  |  DISEASES
270  |  AMPD1  |  DISEASES
3620  |  IDO1  |  DISEASES
54970  |  TTC12  |  DISEASES
6195  |  RPS6KA1  |  DISEASES
60481  |  ELOVL5  |  DISEASES
10846  |  PDE10A  |  DISEASES
5134  |  PDCD2  |  DISEASES
5715  |  PSMD9  |  DISEASES
64478  |  CSMD1  |  DISEASES
51550  |  CINP  |  DISEASES
5027  |  P2RX7  |  DISEASES
169355  |  IDO2  |  DISEASES
6999  |  TDO2  |  DISEASES
8972  |  MGAM  |  DISEASES
79611  |  ACSS3  |  DISEASES
8914  |  TIMELESS  |  DISEASES
53349  |  ZFYVE1  |  DISEASES
91750  |  LIN52  |  DISEASES
132430  |  PABPC4L  |  DISEASES
104355217  |  ERICD  |  DISEASES
101927347  |  GRM7-AS3  |  DISEASES
283120  |  H19  |  DISEASES
100505566  |  LINC00578  |  DISEASES
102216342  |  LINC01108  |  DISEASES
400765  |  MIR137HG  |  DISEASES
100130889  |  PSORS1C3  |  DISEASES
100129060  |  SEMA3F-AS1  |  DISEASES
Locus(Waiting for update.)
Disease ID 1036
Disease mental depression
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:402)
HP:0000739  |  Anxiety  |  242
HP:0012531  |  Pain  |  239
HP:0000726  |  Dementia  |  126
HP:0100543  |  Cognitive deficits  |  114
HP:0012378  |  Fatigue  |  98
HP:0001297  |  Cerebral vascular events  |  71
HP:0001513  |  Obesity  |  68
HP:0007302  |  Bipolar disorder  |  62
HP:0001635  |  Congestive heart failure  |  57
HP:0003002  |  Breast carcinoma  |  54
HP:0012532  |  Chronic pain  |  53
HP:0000819  |  Diabetes mellitus  |  52
HP:0100785  |  Insomnia  |  52
HP:0002099  |  Asthma  |  47
HP:0000708  |  Behavioral problems  |  47
HP:0100753  |  Schizophrenia  |  42
HP:0000709  |  Psychosis  |  38
HP:0012115  |  Liver inflammation  |  35
HP:0002076  |  Migraine headaches  |  34
HP:0003418  |  Back pain  |  34
HP:0000822  |  Hypertension  |  34
HP:0001677  |  Coronary artery disease  |  34
HP:0001369  |  Arthritis  |  31
HP:0002315  |  Headaches  |  29
HP:0012154  |  Anhedonia  |  27
HP:0006510  |  Chronic obstructive pulmonary disease  |  27
HP:0001370  |  Rheumatoid arthritis  |  27
HP:0002360  |  Sleep disturbance  |  27
HP:0001658  |  Myocardial infarction  |  26
HP:0000741  |  Apathy  |  26
HP:0003765  |  Psoriasis  |  25
HP:0100754  |  Mania  |  23
HP:0003419  |  Low back pain  |  23
HP:0000752  |  Hyperactive behavior  |  18
HP:0000718  |  Aggressive behaviour  |  18
HP:0000360  |  Ringing in the ears  |  17
HP:0200123  |  Chronic liver inflammation  |  17
HP:0000737  |  Irritability  |  16
HP:0002664  |  Neoplasia  |  16
HP:0000789  |  Infertility  |  14
HP:0002615  |  Low blood pressure  |  14
HP:0012622  |  Chronic kidney disease  |  13
HP:0001824  |  Weight loss  |  12
HP:0000855  |  Insulin resistance  |  12
HP:0003774  |  End-stage renal failure  |  12
HP:0005110  |  Atrial fibrillation  |  12
HP:0001903  |  Anemia  |  12
HP:0012075  |  Personality disorder  |  11
HP:0012125  |  Prostate cancer  |  11
HP:0001268  |  Mental deterioration  |  10
HP:0000713  |  Agitation  |  10
HP:0001250  |  Seizures  |  10
HP:0002725  |  Systemic lupus erythematosus  |  10
HP:0012076  |  Borderline personality disorder  |  10
HP:0002527  |  Falls  |  9
HP:0001263  |  Developmental retardation  |  9
HP:0001662  |  Bradycardia  |  9
HP:0001631  |  Atria septal defect  |  9
HP:0100806  |  Sepsis  |  9
HP:0003074  |  High blood glucose  |  9
HP:0001061  |  Acne  |  9
HP:0002354  |  Memory loss  |  9
HP:0000821  |  Underactive thyroid  |  9
HP:0007868  |  ARMD  |  8
HP:0100033  |  Tic disorder  |  8
HP:0004395  |  Malnutrition  |  8
HP:0100749  |  Thoracic pain  |  8
HP:0002511  |  Late-onset form of familial Alzheimer disease  |  8
HP:0002894  |  Neoplasia of the pancreas  |  8
HP:0000147  |  Sclerocystic ovaries  |  8
HP:0000722  |  Obsessive compulsive disorder  |  8
HP:0001649  |  Tachycardia  |  8
HP:0002870  |  Obstructive sleep apnea  |  8
HP:0010535  |  Sleep apnea  |  8
HP:0002104  |  Absence of spontaneous respiration  |  8
HP:0000717  |  Autism  |  7
HP:0002018  |  Nausea  |  7
HP:0000501  |  Glaucoma  |  7
HP:0000989  |  pruritis  |  7
HP:0001578  |  Hypercortisolism  |  7
HP:0001945  |  Fever  |  7
HP:0000505  |  Poor vision  |  7
HP:0002020  |  Heartburn  |  6
HP:0000939  |  Osteoporosis  |  6
HP:0002094  |  Dyspnea  |  6
HP:0001262  |  Somnolence  |  6
HP:0011703  |  Sinus tach  |  6
HP:0012432  |  Chronic fatigue  |  6
HP:0000969  |  Dropsy  |  6
HP:0002027  |  Abdominal pain  |  6
HP:0001289  |  Confusion  |  6
HP:0001518  |  Small for gestational age  |  5
HP:0012416  |  Hypercarbia  |  5
HP:0001270  |  Motor retardation  |  5
HP:0001941  |  acidemia  |  5
HP:0001249  |  Mental retardation  |  5
HP:0030692  |  Brain tumor  |  5
HP:0012743  |  Central obesity  |  5
HP:0007354  |  Amyotrophic lateral sclerosis  |  5
HP:0002014  |  Diarrhea  |  5
HP:0000802  |  Erectile dysfunction  |  5
HP:0002180  |  Neurodegeneration  |  4
HP:0002039  |  Anorexia  |  4
HP:0003077  |  Hyperlipidemia  |  4
HP:0100512  |  Vitamin D deficiency  |  4
HP:0002090  |  Pneumonia  |  4
HP:0030731  |  Carcinoma  |  4
HP:0002500  |  Leukoaraiosis  |  4
HP:0002608  |  Celiac disease  |  4
HP:0002960  |  Autoimmune condition  |  4
HP:0001045  |  Blotchy loss of skin color  |  4
HP:0001259  |  Coma  |  4
HP:0000083  |  Renal insufficiency  |  4
HP:0030828  |  Wheezing  |  4
HP:0012228  |  Tension-type headache  |  4
HP:0000135  |  Hypogonadism  |  4
HP:0002110  |  Bronchiectasis  |  4
HP:0002013  |  Emesis  |  4
HP:0200034  |  Papule  |  4
HP:0002835  |  Aspiration  |  4
HP:0001943  |  Hypoglycemia  |  4
HP:0002758  |  Osteoarthritis  |  4
HP:0002583  |  Colitis  |  4
HP:0012188  |  Hyperemesis gravidarum  |  3
HP:0009800  |  gestational diabetes  |  3
HP:0001575  |  Mood alterations  |  3
HP:0000608  |  Macular degeneration  |  3
HP:0004326  |  Cachexia  |  3
HP:0011675  |  Arrhythmias  |  3
HP:0000572  |  Visual loss  |  3
HP:0002621  |  Atherosclerosis  |  3
HP:0001712  |  Left ventricular hypertrophy  |  3
HP:0002321  |  Vertigo  |  3
HP:0001714  |  Ventricular hypertrophy  |  3
HP:0009733  |  Glioma  |  3
HP:0000746  |  Delusions  |  3
HP:0001638  |  Cardiomyopathy  |  3
HP:0002326  |  TIA  |  3
HP:0002381  |  Aphasia  |  3
HP:0002958  |  Immune dysregulation  |  3
HP:0030357  |  Small cell lung carcinoma  |  3
HP:0003287  |  Abnormality of mitochondrial metabolism  |  3
HP:0012735  |  Coughing  |  3
HP:0002045  |  Abnormally low body temperature  |  3
HP:0001254  |  Lethargy  |  3
HP:0100710  |  Impulsivity  |  3
HP:0030358  |  Non-small cell lung carcinoma  |  3
HP:0001332  |  Dystonia  |  3
HP:0100646  |  Thyroiditis  |  3
HP:0002329  |  Drowsiness  |  3
HP:0002015  |  Swallowing difficulty  |  3
HP:0000734  |  Disinhibition  |  3
HP:0002120  |  Cerebral cortical atrophy  |  3
HP:0100279  |  Ulcerative colitis  |  3
HP:0002459  |  Dysautonomia  |  3
HP:0100786  |  Excessive sleepiness  |  3
HP:0000554  |  Uveitis  |  2
HP:0000720  |  Mood swings  |  2
HP:0002578  |  Gastroparesis  |  2
HP:0000510  |  Retinitis pigmentosa  |  2
HP:0001988  |  hypoglycemia, recurrent  |  2
HP:0000365  |  Hearing impairment  |  2
HP:0001394  |  Hepatic cirrhosis  |  2
HP:0000858  |  Menstrual irregularity  |  2
HP:0001751  |  Vestibular dysfunction  |  2
HP:0000836  |  Overactive thyroid  |  2
HP:0012126  |  Gastric cancer  |  2
HP:0012418  |  Low blood oxygen level  |  2
HP:0002910  |  Elevated transaminases  |  2
HP:0007018  |  Attention deficits  |  2
HP:0100242  |  Sarcoma  |  2
HP:0002017  |  Nausea and vomiting  |  2
HP:0000712  |  Emotional instability  |  2
HP:0012387  |  Bronchitis  |  2
HP:0002791  |  Under breathing  |  2
HP:0030329  |  Retinal thinning  |  2
HP:0000518  |  Cataract  |  2
HP:0002140  |  Ischemic stroke  |  2
HP:0001279  |  Syncope  |  2
HP:0001733  |  Pancreatic inflammation  |  2
HP:0040154  |  Hidradenitis suppurativa  |  2
HP:0001915  |  Aplastic anemia  |  2
HP:0002617  |  Aneurysmal dilatation  |  2
HP:0000024  |  Inflammation of the prostate  |  2
HP:0012533  |  Allodynia  |  2
HP:0012722  |  Heart block  |  2
HP:0100570  |  Carcinoid tumor  |  2
HP:0004409  |  Decreased smell sensation  |  2
HP:0005978  |  Noninsulin dependent diabetes mellitus  |  2
HP:0012393  |  Allergy  |  2
HP:0000738  |  Sensory hallucination  |  2
HP:0003560  |  Muscular dystrophy  |  2
HP:0002172  |  Postural instability  |  2
HP:0001278  |  Orthostatic hypotension  |  2
HP:0100495  |  Mastocytosis  |  2
HP:0000488  |  Noninflammatory retina disease  |  2
HP:0000704  |  Pyorrhea  |  2
HP:0002097  |  Pulmonary emphysema  |  2
HP:0011710  |  Bundle-branch block  |  2
HP:0006530  |  Interstitial lung disease  |  2
HP:0001025  |  Hives  |  2
HP:0000020  |  Bladder incontinence  |  2
HP:0001251  |  Ataxia  |  2
HP:0001300  |  Parkinsonism  |  2
HP:0002637  |  Brain ischemia  |  2
HP:0000217  |  Dry mouth syndrome  |  2
HP:0001596  |  Hair loss  |  2
HP:0002721  |  Immunodeficiency  |  2
HP:0003326  |  Muscle pain  |  2
HP:0006349  |  Agenesis of permanent dentition  |  2
HP:0000756  |  Fear of open spaces  |  2
HP:0001873  |  Low platelet count  |  2
HP:0000112  |  Nephropathy  |  2
HP:0030833  |  Neck pain  |  2
HP:0002077  |  Migraine with aura  |  2
HP:0001342  |  Intracerebral hemorrhage  |  2
HP:0001909  |  Leukemia  |  2
HP:0006280  |  Chronic pancreas inflammation  |  2
HP:0002092  |  Pulmonary artery hypertension  |  2
HP:0002634  |  Arteriosclerosis  |  2
HP:0012122  |  Anterior uveitis  |  2
HP:0000017  |  Nocturia  |  2
HP:0000938  |  Decreased bone mineral density  |  1
HP:0003249  |  Genital ulcers  |  1
HP:0004944  |  Cerebral artery aneurysm  |  1
HP:0030858  |  Addictive behavior  |  1
HP:0012189  |  Hodgkin disease  |  1
HP:0200136  |  Oral-pharyngeal dysphagia  |  1
HP:0002206  |  Pulmonary fibrosis  |  1
HP:0012715  |  Profound hearing impairment  |  1
HP:0003764  |  Naevus  |  1
HP:0004324  |  Increased body weight  |  1
HP:0001681  |  Angina pectoris  |  1
HP:0004756  |  Ventricular tachycardia  |  1
HP:0040113  |  Old-aged sensorineural hearing impairment  |  1
HP:0001678  |  Atrioventricular block  |  1
HP:0100598  |  Pulmonary oedema  |  1
HP:0003040  |  Arthropathy  |  1
HP:0030839  |  Knee pain  |  1
HP:0003202  |  Neurogenic muscle atrophy, especially in the lower limbs  |  1
HP:0000751  |  Personality changes  |  1
HP:0002155  |  Increased triglycerides  |  1
HP:0002619  |  Varicose veins  |  1
HP:0001337  |  Tremor  |  1
HP:0000577  |  Exotropia  |  1
HP:0001350  |  Slurred speech  |  1
HP:0001252  |  Hypotonia  |  1
HP:0100660  |  Dyskinesis  |  1
HP:0012384  |  Nasal inflammation  |  1
HP:0002271  |  Autonomic dysregulation  |  1
HP:0012398  |  Peripheral edema  |  1
HP:0003270  |  Distended abdomen  |  1
HP:0002133  |  Status epilepticus  |  1
HP:0000670  |  Dental caries  |  1
HP:0006528  |  Chronic lung disease  |  1
HP:0100502  |  Vitamin B12 deficiency  |  1
HP:0004308  |  Ventricular arrhythmia  |  1
HP:0030764  |  Ochronosis  |  1
HP:0001876  |  Low blood cell count  |  1
HP:0011800  |  Midface, flat  |  1
HP:0002893  |  Pituitary adenoma  |  1
HP:0100507  |  Folate deficiency  |  1
HP:0001888  |  Lymphocytopenia  |  1
HP:0100724  |  Hypercoagulability  |  1
HP:0009830  |  Peripheral neuritis  |  1
HP:0012534  |  Dysesthesia  |  1
HP:0001688  |  Sinus bradycardia  |  1
HP:0001047  |  Atopic dermatitis  |  1
HP:0012049  |  Spasmodic dysphonia  |  1
HP:0001891  |  Iron-deficiency anemia  |  1
HP:0100280  |  Morbus Crohn  |  1
HP:0008220  |  Glucocorticoid insufficiency  |  1
HP:0100607  |  Painful menstruation  |  1
HP:0005943  |  Respiratory arrest  |  1
HP:0000926  |  Flattened vertebral bodies  |  1
HP:0012594  |  High urine albumin levels  |  1
HP:0030854  |  Scleral staphyloma  |  1
HP:0000964  |  Eczema  |  1
HP:0010780  |  Hyperacusis  |  1
HP:0004386  |  Gastrointestinal inflammation  |  1
HP:0002153  |  Elevated serum potassium levels  |  1
HP:0002383  |  Encephalitis  |  1
HP:0002488  |  Acute leukemias  |  1
HP:0002183  |  Fear of loud sounds  |  1
HP:0011856  |  Pica  |  1
HP:0012197  |  Insulinoma  |  1
HP:0002357  |  Dysphasia  |  1
HP:0001288  |  Gait disturbance  |  1
HP:0000575  |  Scotoma  |  1
HP:0011665  |  Takotsubo cardiomyopathy  |  1
HP:0000486  |  Squint eyes  |  1
HP:0002592  |  Stomach ulcer  |  1
HP:0000787  |  Renal calculi  |  1
HP:0030448  |  Soft tissue sarcoma  |  1
HP:0002650  |  Scoliosis  |  1
HP:0005184  |  Prolonged QTc interval  |  1
HP:0000651  |  Diplopia  |  1
HP:0003763  |  Bruxism  |  1
HP:0001410  |  Decreased liver function  |  1
HP:0040213  |  Hypopnea  |  1
HP:0000745  |  Lack of motivation  |  1
HP:0001923  |  Reticulocytosis  |  1
HP:0030151  |  Cholangitis  |  1
HP:0002093  |  progressive respiratory failure  |  1
HP:0002917  |  Low blood magnesium levels  |  1
HP:0007366  |  Brainstem atrophy  |  1
HP:0002883  |  Rapid breathing  |  1
HP:0030892  |  DWMH  |  1
HP:0003401  |  Paresthesia  |  1
HP:0001344  |  Absent speech development  |  1
HP:0030498  |  Macular thickening  |  1
HP:0000833  |  Glucose intolerance  |  1
HP:0010865  |  Oppositional defiant disorder  |  1
HP:0003416  |  Spinal canal stenosis  |  1
HP:0001639  |  Hypertrophic cardiomyopathy  |  1
HP:0012876  |  Premature ejaculation  |  1
HP:0000820  |  Thyroid abnormality  |  1
HP:0005086  |  Knee osteoarthritis  |  1
HP:0001257  |  Spasticity  |  1
HP:0012538  |  Gluten sensitivity  |  1
HP:0011970  |  Cerebral amyloid angiopathy  |  1
HP:0000975  |  Increased sweating  |  1
HP:0100022  |  Movement disorder  |  1
HP:0001644  |  Congestive cardiomyopathy  |  1
HP:0002189  |  Excessive daytime sleepiness  |  1
HP:0001695  |  Cardiac arrest  |  1
HP:0002896  |  Liver cancer  |  1
HP:0002083  |  Migraine without aura  |  1
HP:0000988  |  Exanthem  |  1
HP:0002072  |  Chorea  |  1
HP:0000490  |  Sunken eyes  |  1
HP:0010280  |  Stomatitis  |  1
HP:0001645  |  Sudden cardiac death  |  1
HP:0002591  |  Voracious appetite  |  1
HP:0030805  |  Absent lunula  |  1
HP:0001371  |  Flexion contractures of joints  |  1
HP:0002307  |  Sialorrhea  |  1
HP:0012089  |  Arteritis  |  1
HP:0200025  |  Mandibular pain  |  1
HP:0000648  |  Optic-nerve degeneration  |  1
HP:0100699  |  Scarring  |  1
HP:0011999  |  Paranoia  |  1
HP:0001397  |  Hepatic steatosis  |  1
HP:0001067  |  Neurofibromas  |  1
HP:0006480  |  Premature loss of teeth  |  1
HP:0000458  |  Anosmia  |  1
HP:0008760  |  Violent behavior  |  1
HP:0008200  |  Primary hyperparathyroidism  |  1
HP:0000845  |  Acromegalic growth  |  1
HP:0100009  |  Intracranial meningioma  |  1
HP:0002098  |  Respiratory distress  |  1
HP:0002900  |  Hypokalemia  |  1
HP:0001548  |  Overgrowth  |  1
HP:0100315  |  Lewy bodies  |  1
HP:0011712  |  Right bundle-branch block  |  1
HP:0001889  |  Megaloblastic anemia  |  1
HP:0007281  |  Developmental stagnation  |  1
HP:0001271  |  Polyneuropathy  |  1
HP:0011120  |  Saddle nose  |  1
HP:0030149  |  Cardiovascular shock  |  1
HP:0004929  |  Coronary artherosclerosis  |  1
HP:0001107  |  Albinism, Ocular  |  1
HP:0010447  |  Fistula in ano  |  1
HP:0003546  |  Exercise intolerance  |  1
HP:0004469  |  Chronic bronchitis  |  1
HP:0001510  |  Growth deficiency  |  1
HP:0011107  |  Recurrent aphthous stomatitis  |  1
HP:0004373  |  Focal dystonia  |  1
HP:0001511  |  Prenatal onset growth retardation  |  1
HP:0030838  |  Hip pain  |  1
HP:0001402  |  Hepatocellular carcinoma  |  1
HP:0004749  |  Atrial flutter  |  1
HP:0002665  |  Lymphoma  |  1
HP:0002586  |  Peritonitis  |  1
HP:0004757  |  Paroxysmal atrial fibrillation  |  1
HP:0000603  |  Central scotomata  |  1
HP:0030186  |  Essential tremor  |  1
HP:0001081  |  Gallstones  |  1
HP:0004322  |  Stature below 3rd percentile  |  1
HP:0000843  |  Hyperparathyroidism  |  1
HP:0010783  |  Erythema  |  1
HP:0030050  |  Narcolepsy  |  1
HP:0000498  |  Inflammation of eyelids  |  1
HP:0002901  |  Hypocalcemia  |  1
HP:0012452  |  Restless legs  |  1
HP:0009940  |  Lower jaw shifted to one side  |  1
HP:0100546  |  Narrowing of carotid artery  |  1
HP:0005972  |  Respiratory acidosis  |  1
HP:0012664  |  Reduced ejection fraction  |  1
HP:0001287  |  Meningitis  |  1
HP:0003470  |  Inability to move  |  1
HP:0002524  |  Cataplexy  |  1
HP:0002080  |  Intention tremor  |  1
HP:0100739  |  Binge and purge  |  1
HP:0011110  |  Inflammation of tonsils  |  1
HP:0002204  |  Pulmonary embolism  |  1
HP:0005263  |  Gastritis  |  1
HP:0002019  |  Dyschezia  |  1
HP:0030834  |  Shoulder pain  |  1
HP:0006562  |  Viral hepatitis  |  1
HP:0002781  |  Upper airway obstruction  |  1
HP:0002063  |  Muscle rigidity  |  1
Disease ID 1036
Disease mental depression
Manually Symptom(Waiting for update.)
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:87)
C0003467  |  anxiety  |  242
C0030193  |  pain  |  239
C0086132  |  depressive symptoms  |  167
C0497327  |  dementia  |  126
C0011860  |  type 2 diabetes  |  113
C0015672  |  fatigue  |  98
C0018799  |  heart disease  |  89
C0426768  |  o sign  |  84
C0231303  |  distress  |  74
C0028754  |  obesity  |  68
C0010068  |  coronary heart disease  |  64
C0005586  |  bipolar disorder  |  62
C0277787  |  stigma  |  59
C0150055  |  chronic pain  |  53
C0917801  |  insomnia  |  52
C0007222  |  cardiovascular disease  |  50
C0683323  |  physical illness  |  38
C0033975  |  psychosis  |  38
C0679466  |  cognitive deficits  |  34
C0020538  |  hypertension  |  34
C0178417  |  anhedonia  |  27
C0085632  |  apathy  |  26
C0871189  |  psychotic symptoms  |  24
C0027051  |  myocardial infarction  |  24
C0796095  |  c syndrome  |  21
C0422833  |  ent symptoms  |  20
C0948265  |  metabolic syndrome  |  19
C0037317  |  sleep disturbance  |  18
C0233401  |  psychiatric symptoms  |  15
C0033953  |  sexual dysfunction  |  15
C0150041  |  hopelessness  |  13
C0085631  |  agitation  |  10
C0004936  |  mental disorders  |  10
C1839611  |  n syndrome  |  9
C0020676  |  hypothyroidism  |  9
C0426980  |  motor symptoms  |  9
C0037317  |  sleep disturbances  |  9
C0013473  |  eating disorders  |  8
C0007398  |  catatonia  |  8
C0008031  |  chest pain  |  8
C0001622  |  hypercortisolism  |  7
C0033774  |  pruritus  |  7
C0525041  |  cognitive symptoms  |  7
C1718184  |  pain symptoms  |  7
C0235169  |  excitability  |  7
C0086439  |  hypoactivity  |  5
C0011206  |  delirium  |  5
C0242350  |  erectile dysfunction  |  5
C0040188  |  tic disorders  |  5
C0851578  |  sleep disorder  |  5
C0598639  |  hypercortisolemia  |  5
C0815110  |  perfectionism  |  5
C0042963  |  vomiting  |  4
C0037317  |  disturbed sleep  |  4
C0001726  |  affective symptoms  |  4
C1393529  |  vascular complications  |  4
C0917799  |  hypersomnia  |  3
C0002622  |  memory loss  |  3
C0029118  |  opportunistic infection  |  3
C0023380  |  lethargy  |  3
C0027051  |  myocardial infarction (mi)  |  3
C0001973  |  alcoholism  |  3
C0679309  |  somatic manifestation  |  3
C0018524  |  hallucinations  |  2
C0028768  |  obsessive compulsive disorder  |  2
C0002111  |  allergy  |  2
C0851578  |  sleep disorders  |  2
C0014130  |  endocrine disturbance  |  2
C0031212  |  personality disorders  |  1
C0242422  |  parkinsonism  |  1
C0021053  |  immune disorders  |  1
C0240735  |  personality changes  |  1
C0262405  |  brain dysfunction  |  1
C0034880  |  hyperacusis  |  1
C2220255  |  motor disturbances  |  1
C0029166  |  oral manifestation  |  1
C0175696  |  g syndrome  |  1
C0920350  |  autoimmune thyroiditis  |  1
C0004941  |  behavioral symptom  |  1
C0040822  |  tremor  |  1
C0392156  |  akathisia  |  1
C0009951  |  convulsions  |  1
C0348024  |  thyroid dysfunction  |  1
C0016412  |  folate deficiency  |  1
C1841971  |  glucocorticoid resistance  |  1
C0398623  |  hypercoagulability  |  1
C0751265  |  learning disabilities  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:306)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs1006737193880022984GUCY2Cumls:C0011570BeFreeCaucasian non-Hispanic participants in the STAR*D study of treatment for depression for whom DNA was available (N = 1213) were genotyped at two single-nucleotide polymorphisms (SNPs) (rs10848635 and rs1006737) in the CACNA1C gene.0.0029858612010CACNA1C122236129GA
rs1006737202265365027P2RX7umls:C0011570BeFreeP2RX7:2230912 and CACNA1C:rs1006737 did not have a large or moderate-size effect on depression risk.0.0090011892010CACNA1C122236129GA
rs100673719388002775CACNA1Cumls:C0011570BeFreeCaucasian non-Hispanic participants in the STAR*D study of treatment for depression for whom DNA was available (N = 1213) were genotyped at two single-nucleotide polymorphisms (SNPs) (rs10848635 and rs1006737) in the CACNA1C gene.0.0060912732010CACNA1C122236129GA
rs100673720226536775CACNA1Cumls:C0011570BeFreeP2RX7:2230912 and CACNA1C:rs1006737 did not have a large or moderate-size effect on depression risk.0.0060912732010CACNA1C122236129GA
rs104105442371274922933SIRT2umls:C0011570BeFreeAssociation between Sirtuin 2 gene rs10410544 polymorphism and depression in Alzheimer's disease in two independent European samples.0.0002714422013SIRT21938894892TC
rs1043307246481625715PSMD9umls:C0011570BeFreePSMD9 SNP rs74421874 [intervening sequence (IVS) 3 + nt460 G>A], rs3825172 (IVS3 + nt437 C>T) and rs1043307/rs2514259 (E197G A>G) are all linked to type 2 diabetes (T2D), maturity-onset-diabetes-of the young 3 (MODY3), obesity and waist circumference, hypertension, hypercholesterolemia, T2D-macrovascular and T2D-microvascular disease, T2D-neuropathy, T2D-carpal tunnel syndrome, T2D-nephropathy, T2D-retinopathy, non-diabetic retinopathy and depression.0.0029099162014NANANANANA
rs1045642245770695243ABCB1umls:C0011570BeFreeImplication of P-glycoprotein in formation of depression-prone personality: association study between the C3435T MDR1 gene polymorphism and interpersonal sensitivity.0.0090011892013ABCB1787509329AT,G
rs10487506230261322984GUCY2Cumls:C0011570BeFreeIn an additional meta-analysis combining results from the MARS study with data from the Genome-based Therapeutic Drugs for Depression (GENDEP) and the Sequenced Treatment Alternatives to Relieve Depression (STAR(⁎)D) studies, nominal associations of several polymorphisms in the upstream vicinity of rs10487506 with treatment outcome were detected (p=0.001).0.0029858612012LOC1053754947128238102GA
rs10493532239320456144PCDHA4umls:C0011570BeFreeConsistent with preclinical findings, a synonymous CNR1 polymorphism, rs1049353, is linked to the effects of stress attributable to childhood physical abuse on anhedonia and anhedonic depression.0.0008143262012CNR1688143916CT
rs1050108721188787627BDNFumls:C0011570BeFreeTwo hundred and six patients with Diagnostic and Statistical Manual of Mental Disorders-IV MDD were recruited for this study and genotyped for eight BDNF tagging SNPs (rs11030096, rs925946, rs10501087,rs6265, rs12273363, rs908867, rs1491850, and rs1491851)to investigate the functional impact of genotypes/haplotypes in the susceptibility of depression and on treatment response.0.1197186072011BDNF-AS1127648561TC
rs10514585208002211012CDH13umls:C0011570GAD[These findings suggest shared genetic basis underlying the continuum from personality traits to psychopathology.]0.0023670322010CDH131683250733GA
rs1076607524673294406ARNTLumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0034527992015ARNTL1113297040CT
rs10766075246732949575CLOCKumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0042671252015ARNTL1113297040CT
rs108221420174623948CD36umls:C0011570BeFreeWe found significant association between TIMELESS variants and depression with fatigue (D+FAT+) (rs7486220: pointwise P = 0.000099, OR = 1.66; corrected empirical P for the model of D+FAT+ = 0.0056; haplotype 'C-A-A-C' of rs2291739-rs2291738-rs7486220-rs1082214: P = 0.0000075, OR = 1.72) in females, and association to depression with early morning awakening (D+EMA+) (rs1082214: pointwise P = 0.0009, OR = 2.70; corrected empirical P = 0.0374 for the model D+EMA+; haplotype 'G-T' of rs7486220 and rs1082214: P = 0.0001, OR = 3.01) in males.0.0002714422010MIP1256452706CT
rs1082214201746234582MUC1umls:C0011570BeFreeWe found significant association between TIMELESS variants and depression with fatigue (D+FAT+) (rs7486220: pointwise P = 0.000099, OR = 1.66; corrected empirical P for the model of D+FAT+ = 0.0056; haplotype 'C-A-A-C' of rs2291739-rs2291738-rs7486220-rs1082214: P = 0.0000075, OR = 1.72) in females, and association to depression with early morning awakening (D+EMA+) (rs1082214: pointwise P = 0.0009, OR = 2.70; corrected empirical P = 0.0374 for the model D+EMA+; haplotype 'G-T' of rs7486220 and rs1082214: P = 0.0001, OR = 3.01) in males.0.0002714422010MIP1256452706CT
rs10848635193880022984GUCY2Cumls:C0011570BeFreeCaucasian non-Hispanic participants in the STAR*D study of treatment for depression for whom DNA was available (N = 1213) were genotyped at two single-nucleotide polymorphisms (SNPs) (rs10848635 and rs1006737) in the CACNA1C gene.0.0029858612010CACNA1C122207029TA
rs1084863519388002775CACNA1Cumls:C0011570BeFreeCaucasian non-Hispanic participants in the STAR*D study of treatment for depression for whom DNA was available (N = 1213) were genotyped at two single-nucleotide polymorphisms (SNPs) (rs10848635 and rs1006737) in the CACNA1C gene.0.0060912732010CACNA1C122207029TA
rs11009175208002213688ITGB1umls:C0011570GAD[These findings suggest shared genetic basis underlying the continuum from personality traits to psychopathology.]0.0023670322010LOC1019294751033005847GA
rs11022778246732949575CLOCKumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0042671252015ARNTL;LOC1053765591113369313TG
rs1102277824673294406ARNTLumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0034527992015ARNTL;LOC1053765591113369313TG
rs1103009621188787627BDNFumls:C0011570BeFreeTwo hundred and six patients with Diagnostic and Statistical Manual of Mental Disorders-IV MDD were recruited for this study and genotyped for eight BDNF tagging SNPs (rs11030096, rs925946, rs10501087,rs6265, rs12273363, rs908867, rs1491850, and rs1491851)to investigate the functional impact of genotypes/haplotypes in the susceptibility of depression and on treatment response.0.1197186072011BDNF-AS1127643996TC
rs1103010123532066627BDNFumls:C0011570BeFreeThe aim of the present study was to test for a possible association between two brain-derived neurotrophic factor (BDNF) polymorphisms (rs11030101 and rs61888800) and the efficacy of electroconvulsive therapy (ECT) [change in Montgomery-Åsberg Depression Rating Scale (MADRS)].0.1197186072013BDNF;BDNF-AS1127659197AT
rs11111243246162668GDNFumls:C0011570BeFreeHere we present an association study between eight (rs1981844, rs3812047, rs3096140, rs2973041, rs2910702, rs1549250, rs2973050 and rs11111) GDNF single nucleotide polymorphisms (SNPs) and anxiety and depression scores measured by the Hospital Anxiety and Depression Scale (HADS) on 708 Caucasian young adults with no psychiatric history.0.0010857672013GDNF537814000TC
rs11636753222418301143CHRNB4umls:C0011570BeFreeAlso, rs11636753 in CHRNB4 showed suggestive association with regular drinking (p = .0029) and the comorbidity of depression and ND (p = .0034).0.0002714422012CHRNB41578636604GT
rs1182409224673294406ARNTLumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0034527992015ARNTL1113324747TC
rs11824092246732949575CLOCKumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0042671252015ARNTL1113324747TC
rs1190481419548263121278TPH2umls:C0011570BeFreeThe major findings were associations of TPH2 (rs12229394) with depression accompanied by fatigue in women and CREB1 (rs11904814) with depression alone in men.0.0275464512010CREB12207562074TG
rs11904814195482631385CREB1umls:C0011570BeFreeThe major findings were associations of TPH2 (rs12229394) with depression accompanied by fatigue in women and CREB1 (rs11904814) with depression alone in men.0.0119111052010CREB12207562074TG
rs11911834194971636285S100Bumls:C0011570BeFreeSignificant differences in the subgroup depression (first-episode and recurrent depression) were also shown in 3 genotypes of S100B rs9722 and rs11911834 in patients and control subjects (P < 0.05).0.0010857672009S100B2146602608GT
rs1193259524673294406ARNTLumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0034527992015CLOCK455457430AG
rs11932595246732949575CLOCKumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0042671252015CLOCK455457430AG
rs12007417523467366121278TPH2umls:C0011570BeFreeHere we use chronic multicircuit neurophysiological recordings to characterize functional interactions across cortical and limbic circuits in mice engineered to express a human loss-of-function depression allele Tph2-(R441H) [Tph2 knockin (Tph2KI)].0.0275464512013TPH21272031544GA
rs120525603415140913PPIAP10umls:C0011570BeFreeCRP gene variants were associated with serum levels in a gender-specific manner, but only rs1205 was found to be nominally associated with both an increased risk of DEP and lower circulating CRP levels in women.0.0008143262014CRP1159712443CT
rs1212171240479667133TNFRSF1Bumls:C0011570BeFreeTherefore, we examined whether a single-nucleotide polymorphism in the BDNF gene (rs56164415) and related receptors TrkB (rs1212171) and p75 (rs2072446) were associated with depression in HIV-infected individuals.0.0005428842013NTRK2984667612CT
rs121217124047966627BDNFumls:C0011570BeFreeTherefore, we examined whether a single-nucleotide polymorphism in the BDNF gene (rs56164415) and related receptors TrkB (rs1212171) and p75 (rs2072446) were associated with depression in HIV-infected individuals.0.1197186072013NTRK2984667612CT
rs121374172148343027185DISC1umls:C0011570BeFreeCognitive measures of working memory (rs2793094, P=3.38 × 10(-4)), as well as lifetime history of depression (rs4658966, P=4.33 × 10(-4); rs12137417, P=4.93 × 10(-4)) and panic (rs12137417, P=7.41 × 10(-4)) were associated with DISC1 sequence variation.0.0077199252011DISC1;TSNAX-DISC11231950407GA
rs12229394195482631385CREB1umls:C0011570BeFreeThe major findings were associations of TPH2 (rs12229394) with depression accompanied by fatigue in women and CREB1 (rs11904814) with depression alone in men.0.0119111052010TPH21271999134GA
rs1222939419548263121278TPH2umls:C0011570BeFreeThe major findings were associations of TPH2 (rs12229394) with depression accompanied by fatigue in women and CREB1 (rs11904814) with depression alone in men.0.0275464512010TPH21271999134GA
rs1227336321188787627BDNFumls:C0011570BeFreeTwo hundred and six patients with Diagnostic and Statistical Manual of Mental Disorders-IV MDD were recruited for this study and genotyped for eight BDNF tagging SNPs (rs11030096, rs925946, rs10501087,rs6265, rs12273363, rs908867, rs1491850, and rs1491851)to investigate the functional impact of genotypes/haplotypes in the susceptibility of depression and on treatment response.0.1197186072011BDNF1127723312TC
rs12420464208002218665EIF3Fumls:C0011570GAD[These findings suggest shared genetic basis underlying the continuum from personality traits to psychopathology.]0.0023670322010EIF3F117993230GT
rs12912233208002216095RORAumls:C0011570BeFreeMeta-analytic results for genotyped or imputed single nucleotide polymorphisms indicate that the strongest association signals for trait depression were found in RORA (rs12912233; p = 6 × 10⁻⁷), a gene involved in circadian rhythm.0.1252769482010RORA1560974897CT
rs12912233208002216095RORAumls:C0011570GWASCATMeta-analytic results for genotyped or imputed single nucleotide polymorphisms indicate that the strongest association signals for trait depression were found in RORA (rs12912233; p = 6 × 10⁻⁷), a gene involved in circadian rhythm.0.1252769482010RORA1560974897CT
rs1360780255224202289FKBP5umls:C0011570BeFreeThe FKBP5 rs1360780 polymorphism is associated with plasma cortisol and FKBP5 mRNA expression after psychosocial stress in healthy controls but not in remitted depression.0.0180783232015FKBP5;LOC105375032635639794TC
rs1360780231573397166TPH1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0261132972013FKBP5;LOC105375032635639794TC
rs1360780231573391636ACEumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0132683142013FKBP5;LOC105375032635639794TC
rs1360780216547332289FKBP5umls:C0011570BeFreeThis study revealed interactions between physical abuse and rs1360780 of the FKBP5 gene, confirming its role in the individual susceptibility to depression.0.0180783232011FKBP5;LOC105375032635639794TC
rs1360780231573392289FKBP5umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0180783232013FKBP5;LOC105375032635639794TC
rs1360780255224202908NR3C1umls:C0011570BeFreePolymorphisms in the FK506 binding protein 5 (FKBP5) gene have been shown to influence glucocorticoid receptor sensitivity, stress response regulation, and depression risk in traumatized subjects, with most consistent findings reported for the functional variant rs1360780.0.0199784162015FKBP5;LOC105375032635639794TC
rs1360780231573391394CRHR1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0204453552013FKBP5;LOC105375032635639794TC
rs1360780231573394128MAOAumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0328233992013FKBP5;LOC105375032635639794TC
rs1360780231573391312COMTumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0376334072013FKBP5;LOC105375032635639794TC
rs1360780231573395027P2RX7umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0090011892013FKBP5;LOC105375032635639794TC
rs1360780231573393356HTR2Aumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0431058522013FKBP5;LOC105375032635639794TC
rs14259246481625715PSMD9umls:C0011570BeFreePSMD9 SNP rs74421874 [intervening sequence (IVS) 3 + nt460 G>A], rs3825172 (IVS3 + nt437 C>T) and rs1043307/rs2514259 (E197G A>G) are all linked to type 2 diabetes (T2D), maturity-onset-diabetes-of the young 3 (MODY3), obesity and waist circumference, hypertension, hypercholesterolemia, T2D-macrovascular and T2D-microvascular disease, T2D-neuropathy, T2D-carpal tunnel syndrome, T2D-nephropathy, T2D-retinopathy, non-diabetic retinopathy and depression.0.0029099162014PSMD912121915890AC,G
rs144998420800221338APOBumls:C0011570GAD[These findings suggest shared genetic basis underlying the continuum from personality traits to psychopathology.]0.0023670322010LOC101929251223191780AG
rs149185021188787627BDNFumls:C0011570BeFreeTwo hundred and six patients with Diagnostic and Statistical Manual of Mental Disorders-IV MDD were recruited for this study and genotyped for eight BDNF tagging SNPs (rs11030096, rs925946, rs10501087,rs6265, rs12273363, rs908867, rs1491850, and rs1491851)to investigate the functional impact of genotypes/haplotypes in the susceptibility of depression and on treatment response.0.1197186072011NA1127728178TC
rs149185121188787627BDNFumls:C0011570BeFreeTwo hundred and six patients with Diagnostic and Statistical Manual of Mental Disorders-IV MDD were recruited for this study and genotyped for eight BDNF tagging SNPs (rs11030096, rs925946, rs10501087,rs6265, rs12273363, rs908867, rs1491850, and rs1491851)to investigate the functional impact of genotypes/haplotypes in the susceptibility of depression and on treatment response.0.1197186072011NA1127731216TC
rs1501299255977959370ADIPOQumls:C0011570BeFreeA longitudinal study of the association of adiponectin gene rs1501299 with depression in Chinese Han adolescents after Wenchuan earthquake.0.0002714422014ADIPOQ;ADIPOQ-AS13186853334GT
rs15458432247562255117SLC6A15umls:C0011570BeFreeRecently, a variant (rs1545843) affecting transcription of the human SLC6A15 gene has been associated with depression in a genome-wide association study.0.0002714422013NA1284170289GA
rs1549250243246162668GDNFumls:C0011570BeFreeHere we present an association study between eight (rs1981844, rs3812047, rs3096140, rs2973041, rs2910702, rs1549250, rs2973050 and rs11111) GDNF single nucleotide polymorphisms (SNPs) and anxiety and depression scores measured by the Hospital Anxiety and Depression Scale (HADS) on 708 Caucasian young adults with no psychiatric history.0.0010857672013GDNF537821119CA
rs156243246732949575CLOCKumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0042671252015NA6104416939GA
rs15624324673294406ARNTLumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0034527992015NA6104416939GA
rs16139234689084852NPYumls:C0011570BeFreeStatistical analysis showed a significant correlation between the SNP sites rs16139 in NPY and the morbidity of depression.0.0103583982013NPY724285260TC,A
rs174697227277091312COMTumls:C0011570BeFreeIn self-identified white patients with major depressive disorder (N=126) treated with open-label duloxetine (60-120 mg/d), a significant association of (P=0.020) of a composite risk score (based on SLC6A2 rs5569 [G1287A] AA, HTR1A rs6295 [C(-1019)G] GG, and COMT rs174697 AA/AG) with 17-item Hamilton Depression Rating Scale total score change from baseline to 12 weeks was observed.0.0376334072012ARVCF;COMT2219966309AG
rs17864092208002212918GRM8umls:C0011570GAD[These findings suggest shared genetic basis underlying the continuum from personality traits to psychopathology.]0.0023670322010GRM87126999550TC
rs1800041149983067166TPH1umls:C0011570BeFreeSpecifically, we investigated two serotonin-related genes including three substitutions connected to human emotional states such as despondency and depression: the tryptophan hydroxylase (TPH) gene (A779C and A218C in the intron) and the serotonin1A (5-HT1A) receptor gene (Pro 16Leu in the cording region).0.0261132972004HTR1A563961673GA
rs1800041149983063350HTR1Aumls:C0011570BeFreeSpecifically, we investigated two serotonin-related genes including three substitutions connected to human emotional states such as despondency and depression: the tryptophan hydroxylase (TPH) gene (A779C and A218C in the intron) and the serotonin1A (5-HT1A) receptor gene (Pro 16Leu in the cording region).0.0516401022004HTR1A563961673GA
rs1800044191052006530SLC6A2umls:C0011570BeFreeIn conclusion, our results favor the hypothesis that monoaminergic neurotransmission in general and the F528C NET and R219L 5-HT(1A) receptor variants in particular are involved in the pathogenesis of depression.0.0192836432009HTR1A563961061CA
rs1800044191052003350HTR1Aumls:C0011570BeFreeIn conclusion, our results favor the hypothesis that monoaminergic neurotransmission in general and the F528C NET and R219L 5-HT(1A) receptor variants in particular are involved in the pathogenesis of depression.0.0516401022009HTR1A563961061CA
rs180049723683269255239ANKK1umls:C0011570BeFreeThe A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D(2/3) receptor binding in healthy individuals (Con) as well as depression and addiction.0.0002714422014ANKK111113400106GA
rs180049723683269284098PIGWumls:C0011570BeFreeThe A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D(2/3) receptor binding in healthy individuals (Con) as well as depression and addiction.0.0002714422014ANKK111113400106GA
rs1800497236832691813DRD2umls:C0011570BeFreeThe A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D(2/3) receptor binding in healthy individuals (Con) as well as depression and addiction.0.0095440732014ANKK111113400106GA
rs1800587241033723552IL1Aumls:C0011570BeFreeInterleukin-1 alpha (rs1800587) genetic polymorphism is associated with specific cognitive functions but not depression or loneliness in elderly males without dementia.0.0010857672013IL1A2112785383GC,A
rs1801394232805734552MTRRumls:C0011570BeFreeThe major finding from this study is that the MTRR A66G genotype predicts response to selective serotonin reuptake inhibitor antidepressants in late life depression.0.0002714422012MTRR;FASTKD357870860AG
rs1805054114428973362HTR6umls:C0011570BeFreeAssociation analysis of the 5-HT6 receptor polymorphism C267T with depression in patients with Alzheimer's disease.0.0050055062001HTR6119666020CT
rs19277452080022155082ARGLU1umls:C0011570GAD[These findings suggest shared genetic basis underlying the continuum from personality traits to psychopathology.]0.0023670322010LOC105370350;LOC10537035113107127968GA
rs1981844243246162668GDNFumls:C0011570BeFreeHere we present an association study between eight (rs1981844, rs3812047, rs3096140, rs2973041, rs2910702, rs1549250, rs2973050 and rs11111) GDNF single nucleotide polymorphisms (SNPs) and anxiety and depression scores measured by the Hospital Anxiety and Depression Scale (HADS) on 708 Caucasian young adults with no psychiatric history.0.0010857672013GDNF-AS1537845041GC,A
rs20173052080022179009DDX50umls:C0011570GAD[These findings suggest shared genetic basis underlying the continuum from personality traits to psychopathology.]0.0023670322010NA1068952306AG
rs2020936195412926532SLC6A4umls:C0011570BeFreeWe found evidence for association (p = .0062, after accounting for multiple testing) for SLC6A4 SNPs rs6354 and rs2020936 (positioned in a different linkage disequilibrium [LD] block about 15.5 kb from 5HTTLPR) with anxiety and/or depression and neuroticism, with the strongest association for recurrent depression with onset in young adulthood (odds ratio = 1.55, 95% confidence interval = 1.16-2.06).0.1546465152009SLC6A41730223796GA
rs207244624047966627BDNFumls:C0011570BeFreeTherefore, we examined whether a single-nucleotide polymorphism in the BDNF gene (rs56164415) and related receptors TrkB (rs1212171) and p75 (rs2072446) were associated with depression in HIV-infected individuals.0.1197186072013NGFR;LOC100288866;MIR61651749510457CT
rs2072446240479667133TNFRSF1Bumls:C0011570BeFreeTherefore, we examined whether a single-nucleotide polymorphism in the BDNF gene (rs56164415) and related receptors TrkB (rs1212171) and p75 (rs2072446) were associated with depression in HIV-infected individuals.0.0005428842013NGFR;LOC100288866;MIR61651749510457CT
rs20756502454910210452TOMM40umls:C0011570BeFreeOur results suggest that TOMM40 rs2075650 may be a risk factor for the development of depression characterized by reduced extraversion, impaired executive function, and decreased positive emotional recall, and reduced top-down cortical control during sad emotion processing.0.0002714422014TOMM401944892362AG
rs2230912188014075027P2RX7umls:C0011570BeFreeP2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients.0.0090011892008P2RX7;LOC10537003212121184393AG
rs2230912231573391312COMTumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0376334072013P2RX7;LOC10537003212121184393AG
rs2230912185432745027P2RX7umls:C0011570BeFreeAssociation between depression and the Gln460Arg polymorphism of P2RX7 gene: a dimensional approach.0.0090011892009P2RX7;LOC10537003212121184393AG
rs2230912231573395027P2RX7umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0090011892013P2RX7;LOC10537003212121184393AG
rs2230912231573391394CRHR1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0204453552013P2RX7;LOC10537003212121184393AG
rs2230912231573397166TPH1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0261132972013P2RX7;LOC10537003212121184393AG
rs2230912231573393356HTR2Aumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0431058522013P2RX7;LOC10537003212121184393AG
rs2230912231573394128MAOAumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0328233992013P2RX7;LOC10537003212121184393AG
rs2230912231573392289FKBP5umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0180783232013P2RX7;LOC10537003212121184393AG
rs2230912231573391636ACEumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0132683142013P2RX7;LOC10537003212121184393AG
rs2234693218041482099ESR1umls:C0011570BeFreeIn women, the ER-α rs2234693 and rs9340799 polymorphisms were significantly associated with the risk of late-life depression.0.0010857672011ESR16151842200TC
rs2253206212153891385CREB1umls:C0011570BeFreeFinally, using functional magnetic resonance imaging, we found that viewing sad faces evoked greater activity in depression-related areas in healthy control subjects possessing the minor alleles of BDNF-rs6265 and CREB1-rs2253206.0.0119111052011NA2207527254AG
rs225320621215389627BDNFumls:C0011570BeFreeFinally, using functional magnetic resonance imaging, we found that viewing sad faces evoked greater activity in depression-related areas in healthy control subjects possessing the minor alleles of BDNF-rs6265 and CREB1-rs2253206.0.1197186072011NA2207527254AG
rs2253206206434831385CREB1umls:C0011570BeFreeOne hundred-ninety MD patients collected in the context of a resistant depression study and treated with antidepressants for at least 4weeks were genotyped for 5 CREB1 SNPs (rs2709376, rs2253206, rs7569963, rs7594560, and rs4675690).0.0119111052011NA2207527254AG
rs2254298225103595021OXTRumls:C0011570BeFreeIt is suggested that polymorphic variation at the oxytocin receptor gene (rs2254298) is associated with sociability, amygdala volume and differential risk for psychiatric conditions including autism, depression and anxiety disorder, depending on the quality of early environmental experiences.0.0039956832012OXTR38760542GA
rs2283265247801471813DRD2umls:C0011570BeFreeFindings for DAT1 intron8 were also significant for two EMD subscales, generalized anxiety (ηp(2)=.065) and depression (ηp(2)=.059), and for DRD2 rs2283265, depression (ηp(2)=.053).0.0095440732014DRD211113414814CA
rs2283265247801476531SLC6A3umls:C0011570BeFreeFindings for DAT1 intron8 were also significant for two EMD subscales, generalized anxiety (ηp(2)=.065) and depression (ηp(2)=.059), and for DRD2 rs2283265, depression (ηp(2)=.053).0.0237462652014DRD211113414814CA
rs22896561984420655729ATF7IPumls:C0011570BeFreeAfter controlling for age, gender and baseline 21-item Hamilton Depression Rating Scale (HAM-D21) score, as well as correcting for multiple testing, the relative reduction of HAM-D21 score remained significantly associated with two NTRK2-coding SNPs (rs2289657 and rs56142442) and the haplotype CAG at rs2289658 (splice site), rs2289657 and rs2289656.0.0027144192009NTRK2984948647GA
rs22896571984420655729ATF7IPumls:C0011570BeFreeAfter controlling for age, gender and baseline 21-item Hamilton Depression Rating Scale (HAM-D21) score, as well as correcting for multiple testing, the relative reduction of HAM-D21 score remained significantly associated with two NTRK2-coding SNPs (rs2289657 and rs56142442) and the haplotype CAG at rs2289658 (splice site), rs2289657 and rs2289656.0.0027144192009NTRK2984948545CA
rs22896581984420655729ATF7IPumls:C0011570BeFreeAfter controlling for age, gender and baseline 21-item Hamilton Depression Rating Scale (HAM-D21) score, as well as correcting for multiple testing, the relative reduction of HAM-D21 score remained significantly associated with two NTRK2-coding SNPs (rs2289657 and rs56142442) and the haplotype CAG at rs2289658 (splice site), rs2289657 and rs2289656.0.0027144192009NTRK2984948455TC
rs229173820174623948CD36umls:C0011570BeFreeWe found significant association between TIMELESS variants and depression with fatigue (D+FAT+) (rs7486220: pointwise P = 0.000099, OR = 1.66; corrected empirical P for the model of D+FAT+ = 0.0056; haplotype 'C-A-A-C' of rs2291739-rs2291738-rs7486220-rs1082214: P = 0.0000075, OR = 1.72) in females, and association to depression with early morning awakening (D+EMA+) (rs1082214: pointwise P = 0.0009, OR = 2.70; corrected empirical P = 0.0374 for the model D+EMA+; haplotype 'G-T' of rs7486220 and rs1082214: P = 0.0001, OR = 3.01) in males.0.0002714422010TIMELESS1256421497TC
rs2291738201746234582MUC1umls:C0011570BeFreeWe found significant association between TIMELESS variants and depression with fatigue (D+FAT+) (rs7486220: pointwise P = 0.000099, OR = 1.66; corrected empirical P for the model of D+FAT+ = 0.0056; haplotype 'C-A-A-C' of rs2291739-rs2291738-rs7486220-rs1082214: P = 0.0000075, OR = 1.72) in females, and association to depression with early morning awakening (D+EMA+) (rs1082214: pointwise P = 0.0009, OR = 2.70; corrected empirical P = 0.0374 for the model D+EMA+; haplotype 'G-T' of rs7486220 and rs1082214: P = 0.0001, OR = 3.01) in males.0.0002714422010TIMELESS1256421497TC
rs229173920174623948CD36umls:C0011570BeFreeWe found significant association between TIMELESS variants and depression with fatigue (D+FAT+) (rs7486220: pointwise P = 0.000099, OR = 1.66; corrected empirical P for the model of D+FAT+ = 0.0056; haplotype 'C-A-A-C' of rs2291739-rs2291738-rs7486220-rs1082214: P = 0.0000075, OR = 1.72) in females, and association to depression with early morning awakening (D+EMA+) (rs1082214: pointwise P = 0.0009, OR = 2.70; corrected empirical P = 0.0374 for the model D+EMA+; haplotype 'G-T' of rs7486220 and rs1082214: P = 0.0001, OR = 3.01) in males.0.0002714422010TIMELESS1256420869GC,A
rs2291739201746234582MUC1umls:C0011570BeFreeWe found significant association between TIMELESS variants and depression with fatigue (D+FAT+) (rs7486220: pointwise P = 0.000099, OR = 1.66; corrected empirical P for the model of D+FAT+ = 0.0056; haplotype 'C-A-A-C' of rs2291739-rs2291738-rs7486220-rs1082214: P = 0.0000075, OR = 1.72) in females, and association to depression with early morning awakening (D+EMA+) (rs1082214: pointwise P = 0.0009, OR = 2.70; corrected empirical P = 0.0374 for the model D+EMA+; haplotype 'G-T' of rs7486220 and rs1082214: P = 0.0001, OR = 3.01) in males.0.0002714422010TIMELESS1256420869GC,A
rs242941231573391394CRHR1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0204453552013CRHR1;MGC57346-CRHR11745815154AC
rs242941231573395027P2RX7umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0090011892013CRHR1;MGC57346-CRHR11745815154AC
rs242941231573391312COMTumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0376334072013CRHR1;MGC57346-CRHR11745815154AC
rs242941231573393356HTR2Aumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0431058522013CRHR1;MGC57346-CRHR11745815154AC
rs242941231573391636ACEumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0132683142013CRHR1;MGC57346-CRHR11745815154AC
rs242941231573392289FKBP5umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0180783232013CRHR1;MGC57346-CRHR11745815154AC
rs242941231573394128MAOAumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0328233992013CRHR1;MGC57346-CRHR11745815154AC
rs242941231573397166TPH1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0261132972013CRHR1;MGC57346-CRHR11745815154AC
rs2514259246481625715PSMD9umls:C0011570BeFreePSMD9 SNP rs74421874 [intervening sequence (IVS) 3 + nt460 G>A], rs3825172 (IVS3 + nt437 C>T) and rs1043307/rs2514259 (E197G A>G) are all linked to type 2 diabetes (T2D), maturity-onset-diabetes-of the young 3 (MODY3), obesity and waist circumference, hypertension, hypercholesterolemia, T2D-macrovascular and T2D-microvascular disease, T2D-neuropathy, T2D-carpal tunnel syndrome, T2D-nephropathy, T2D-retinopathy, non-diabetic retinopathy and depression.0.0029099162014NA1167479201CT
rs25228331994262227445PCLOumls:C0011570BeFreeWe aimed to validate the association of single-nucleotide polymorphism (SNP) rs2522833 in the PCLO gene with depression in the Rotterdam Study, a prospective population-based cohort of elderly persons.0.0016286512010PCLO782824392AC
rs25531205153623350HTR1Aumls:C0011570BeFreeSix functional SNPs in genes related to the serotonergic system were examined: serotonin transporter (5HTTLPR including rs25531), 5HT1A C-(1019)G and 5HT2A T-(102)C, methylene tetrahydrofolate reductase (MTHFR) C-(677)T, brain-derived neurotrophic factor (BDNF) val66met and tryptophan hydroxylase-2 (TPH2) G-(703)T. Regression analyses were performed using the six SNPs as independent variables: Model 1 with response (percentage Hamilton Depression (HAMD) change from baseline to endpoint) as the dependent variable and Model 2 with adverse event index as the dependent variable (Bonferroni corrected p-value < 0.025).0.0516401022010SLC6A4;LOC1053717201730237328TC
rs25531248625606532SLC6A4umls:C0011570BeFreeThe serotonin transporter (5-HTT) and the 5-HTTLPR/rs25531 polymorphisms in its gene (SLC6A4) have been associated with depression, increased stress-response, and brain structural alterations such as reduced hippocampal volumes.0.1546465152014SLC6A4;LOC1053717201730237328TC
rs2553120515362627BDNFumls:C0011570BeFreeSix functional SNPs in genes related to the serotonergic system were examined: serotonin transporter (5HTTLPR including rs25531), 5HT1A C-(1019)G and 5HT2A T-(102)C, methylene tetrahydrofolate reductase (MTHFR) C-(677)T, brain-derived neurotrophic factor (BDNF) val66met and tryptophan hydroxylase-2 (TPH2) G-(703)T. Regression analyses were performed using the six SNPs as independent variables: Model 1 with response (percentage Hamilton Depression (HAMD) change from baseline to endpoint) as the dependent variable and Model 2 with adverse event index as the dependent variable (Bonferroni corrected p-value < 0.025).0.1197186072010SLC6A4;LOC1053717201730237328TC
rs25531180502626532SLC6A4umls:C0011570BeFreeTo further delineate the impact of 5-HTT gene variation on psychopathology in depression, in this analysis the influence of the 5-HTTLPR and the functionally closely related 5-HTT rs25531 was investigated in 340 Caucasian patients with a major depressive episode (DSM-IV) with particular attention to the subtype of depression (melancholic depression versus atypical depression) applying logistic regression models adjusted for age and gender.0.1546465152008SLC6A4;LOC1053717201730237328TC
rs25531194291116532SLC6A4umls:C0011570BeFreeThe present study is to investigate the association between the polymorphisms in the promoter of the 5-HTT gene (including 5-HTTLPR and rs25531), which determine either a higher or lower 5-HT uptake, and risk for depression of PD.0.1546465152009SLC6A4;LOC1053717201730237328TC
rs25531220944326532SLC6A4umls:C0011570BeFreeAlthough preliminary, these findings identify anhedonia as a promising mechanism linking 5-HTTLPR/rs25531 genotype and stress to depression.0.1546465152012SLC6A4;LOC1053717201730237328TC
rs2553120515362121278TPH2umls:C0011570BeFreeSix functional SNPs in genes related to the serotonergic system were examined: serotonin transporter (5HTTLPR including rs25531), 5HT1A C-(1019)G and 5HT2A T-(102)C, methylene tetrahydrofolate reductase (MTHFR) C-(677)T, brain-derived neurotrophic factor (BDNF) val66met and tryptophan hydroxylase-2 (TPH2) G-(703)T. Regression analyses were performed using the six SNPs as independent variables: Model 1 with response (percentage Hamilton Depression (HAMD) change from baseline to endpoint) as the dependent variable and Model 2 with adverse event index as the dependent variable (Bonferroni corrected p-value < 0.025).0.0275464512010SLC6A4;LOC1053717201730237328TC
rs25531244465361312COMTumls:C0011570BeFreeThe aim of our work is to study the possible role of clinical variables, neuropsychological performance, and the 5HTTLPR, rs25531, and val108/58Met COMT polymorphisms on the prediction of depression remission after 12 weeks' treatment with fluoxetine.0.0376334072014SLC6A4;LOC1053717201730237328TC
rs25531205880716530SLC6A2umls:C0011570BeFreeSeven polymorphisms in the promoter, intronic and exonic region of the NET gene, as well as serotonin-transporter-linked promoter region (5-HTTLPR) and 5-HTT rs25531 polymorphisms were analyzed with respect to antidepressant treatment response with particular attention to gender effects and subtypes of melancholic or anxious depression.0.0192836432010SLC6A4;LOC1053717201730237328TC
rs26195222082237284062DTNBP1umls:C0011570BeFreeTwo intronic SNPs of DTNBP1; rs760761 (P1320) and rs2619522 (P1763) were analyzed in 206 patients with DSM-IV MDD to investigate the functional impact of genotypes on susceptibility for depression and some clinical phenotypes.0.0079154222010DTNBP1615653418AC
rs2709376206434831385CREB1umls:C0011570BeFreeOne hundred-ninety MD patients collected in the context of a resistant depression study and treated with antidepressants for at least 4weeks were genotyped for 5 CREB1 SNPs (rs2709376, rs2253206, rs7569963, rs7594560, and rs4675690).0.0119111052011NA2207525664TC
rs27930942148343027185DISC1umls:C0011570BeFreeCognitive measures of working memory (rs2793094, P=3.38 × 10(-4)), as well as lifetime history of depression (rs4658966, P=4.33 × 10(-4); rs12137417, P=4.93 × 10(-4)) and panic (rs12137417, P=7.41 × 10(-4)) were associated with DISC1 sequence variation.0.0077199252011DISC1;TSNAX-DISC11231741236GA
rs2910702243246162668GDNFumls:C0011570BeFreeHere we present an association study between eight (rs1981844, rs3812047, rs3096140, rs2973041, rs2910702, rs1549250, rs2973050 and rs11111) GDNF single nucleotide polymorphisms (SNPs) and anxiety and depression scores measured by the Hospital Anxiety and Depression Scale (HADS) on 708 Caucasian young adults with no psychiatric history.0.0010857672013GDNF537828202CT
rs2973041243246162668GDNFumls:C0011570BeFreeHere we present an association study between eight (rs1981844, rs3812047, rs3096140, rs2973041, rs2910702, rs1549250, rs2973050 and rs11111) GDNF single nucleotide polymorphisms (SNPs) and anxiety and depression scores measured by the Hospital Anxiety and Depression Scale (HADS) on 708 Caucasian young adults with no psychiatric history.0.0010857672013GDNF537830224TC
rs2973050243246162668GDNFumls:C0011570BeFreeHere we present an association study between eight (rs1981844, rs3812047, rs3096140, rs2973041, rs2910702, rs1549250, rs2973050 and rs11111) GDNF single nucleotide polymorphisms (SNPs) and anxiety and depression scores measured by the Hospital Anxiety and Depression Scale (HADS) on 708 Caucasian young adults with no psychiatric history.0.0010857672013GDNF537817242AG
rs3096140243246162668GDNFumls:C0011570BeFreeHere we present an association study between eight (rs1981844, rs3812047, rs3096140, rs2973041, rs2910702, rs1549250, rs2973050 and rs11111) GDNF single nucleotide polymorphisms (SNPs) and anxiety and depression scores measured by the Hospital Anxiety and Depression Scale (HADS) on 708 Caucasian young adults with no psychiatric history.0.0010857672013GDNF537832731GA
rs334558221190866532SLC6A4umls:C0011570BeFreeWe observed a triple interaction of 5-HTTLPR, rs334558 and treatment on severity of depression.0.1546465152012GSK3B3120094435AG
rs3463758424830390120892LRRK2umls:C0011570BeFree(G2019S) LRRK2 causes early-phase dysfunction of SNpc dopaminergic neurons and impairment of corticostriatal long-term depression in the PD transgenic mouse.0.0002714422014LRRK21240340400GA
rs371356064231573391312COMTumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0376334072013P2RX712121133072CT
rs371356064231573392289FKBP5umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0180783232013P2RX712121133072CT
rs371356064231573391394CRHR1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0204453552013P2RX712121133072CT
rs371356064231573394128MAOAumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0328233992013P2RX712121133072CT
rs371356064231573395027P2RX7umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0090011892013P2RX712121133072CT
rs371356064231573393356HTR2Aumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0431058522013P2RX712121133072CT
rs371356064231573391636ACEumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0132683142013P2RX712121133072CT
rs371356064231573397166TPH1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0261132972013P2RX712121133072CT
rs378932724673294406ARNTLumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0034527992015ARNTL;LOC1053765591113363769AG
rs3789327246732949575CLOCKumls:C0011570BeFreeIn epistatic interaction analyses, we observed two locus interactions between sleep disturbances (p = 0.007; rs11824092 of ARNTL and rs11932595 of CLOCK) as well as interactions of subdimension in main depression and ARNTL variants (p = 0.0011; rs3789327, rs10766075) and appetite disturbances in depression and ARNTL polymorphism (p = 7 × 10(-4); rs11022778, rs156243).0.0042671252015ARNTL;LOC1053765591113363769AG
rs3794808209810386532SLC6A4umls:C0011570BeFreeThe major allele of another SNP of SLC6A4, namely rs3794808, correlated with the HADS depression score (P = 0.016).0.1546465152011SLC6A41730204775CT
rs3812047243246162668GDNFumls:C0011570BeFreeHere we present an association study between eight (rs1981844, rs3812047, rs3096140, rs2973041, rs2910702, rs1549250, rs2973050 and rs11111) GDNF single nucleotide polymorphisms (SNPs) and anxiety and depression scores measured by the Hospital Anxiety and Depression Scale (HADS) on 708 Caucasian young adults with no psychiatric history.0.0010857672013GDNF537835296CT
rs3825172246481625715PSMD9umls:C0011570BeFreePSMD9 SNP rs74421874 [intervening sequence (IVS) 3 + nt460 G>A], rs3825172 (IVS3 + nt437 C>T) and rs1043307/rs2514259 (E197G A>G) are all linked to type 2 diabetes (T2D), maturity-onset-diabetes-of the young 3 (MODY3), obesity and waist circumference, hypertension, hypercholesterolemia, T2D-macrovascular and T2D-microvascular disease, T2D-neuropathy, T2D-carpal tunnel syndrome, T2D-nephropathy, T2D-retinopathy, non-diabetic retinopathy and depression.0.0029099162014PSMD912121902569CT
rs386599040227277091312COMTumls:C0011570BeFreeIn self-identified white patients with major depressive disorder (N=126) treated with open-label duloxetine (60-120 mg/d), a significant association of (P=0.020) of a composite risk score (based on SLC6A2 rs5569 [G1287A] AA, HTR1A rs6295 [C(-1019)G] GG, and COMT rs174697 AA/AG) with 17-item Hamilton Depression Rating Scale total score change from baseline to 12 weeks was observed.0.0376334072012NANANANANA
rs38660211822610920627BDNFumls:C0011570BeFreeThe brain-derived neurotrophic-factor (BDNF) val66met polymorphism is associated with geriatric depression: a meta-analysis.0.1197186072012NANANANANA
rs386602118193390526532SLC6A4umls:C0011570BeFreeThe low activity variants of the 5-HTT-linked polymorphic region in the serotonin transporter gene and the Met-allele of a single nucleotide polymorphism (Val66Met) in the gene encoding brain derived neurotrophic factor were independently associated with the presence of stressful life events prior to onset of depression, also when corrected for the effect of age, gender, marital status, personality disorder, neuroticism, and severity of depressive symptoms at the time of interview.0.1546465152009NANANANANA
rs38660211825745134627BDNFumls:C0011570BeFreeModulatory effects of the BDNF Val66Met polymorphism on distinct subregions in the prefrontal cortex in MDD support the neurotrophin model of depression.0.1197186072014NANANANANA
rs38660211820921572627BDNFumls:C0011570BeFreeWe therefore examined whether the single-nucleotide polymorphism producing a valine-to-methionine substitution at codon 66 (val66met) of the BDNF gene was associated with childhood NE, in the context of parental depression and relationship discord.0.1197186072010NANANANANA
rs38660211820728877627BDNFumls:C0011570BeFreeEarly life stress combined with serotonin 3A receptor and brain-derived neurotrophic factor valine 66 to methionine genotypes impacts emotional brain and arousal correlates of risk for depression.0.1197186072010NANANANANA
rs38660211822883353627BDNFumls:C0011570BeFreeDiscussion The dynamics of serum BDNF levels, but not plasma levels of HVA and MHPG, reflect the response to mirtazapine treatment; the BDNF Val66Met polymorphism in patients with depression is, however, associated with neither a particular response to mirtazapine treatment nor baseline serum BDNF levels.0.1197186072012NANANANANA
rs38660211822033217627BDNFumls:C0011570BeFreeThe results suggest that in males, BDNF Val66Met interacts with childhood life events, increasing the cognitive susceptibility markers of depression.0.1197186072012NANANANANA
rs386602118184503786532SLC6A4umls:C0011570BeFree5-HTTLPR and BDNF Val66Met polymorphisms and response to rTMS treatment in drug resistant depression.0.1546465152008NANANANANA
rs38660211817941097627BDNFumls:C0011570BeFreeTwo common functional polymorphisms in catechol-O-methyltransferase (COMT Val158Met) and brain-derived neurotrophic factor (BDNF Val66Met) genes have been implicated in the neurobiology of anxiety and depression.0.1197186072008NANANANANA
rs38660211820667416627BDNFumls:C0011570BeFreeA functional BDNF polymorphism (BDNF Val66Met) was reported to influence the effects of stressful life events or childhood adversity on depression and suicidal behaviour in various psychopathologies.0.1197186072011NANANANANA
rs38660211818263664627BDNFumls:C0011570BeFreeThe brain-derived neurotrophic factor VAL66MET polymorphism and cerebral white matter hyperintensities in late-life depression.0.1197186072008NANANANANA
rs38660211821577214627BDNFumls:C0011570BeFreeGiven that BDNF secretion is affected by a common polymorphism (rs6265, Val66Met), which also is associated with depression, we investigated whether this polymorphism modifies the effect of childhood adversity (CA) on local gray matter (GM) volume in depression-relevant brain regions, using data from two large cohorts of healthy subjects.0.1197186072012NANANANANA
rs38660211817959306627BDNFumls:C0011570BeFreeRumination may be an endophenotype in the pathway from the BDNF Val66Met polymorphism to depression.0.1197186072007NANANANANA
rs386602118231573392289FKBP5umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0180783232013NANANANANA
rs38660211816343697627BDNFumls:C0011570BeFreeThe Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression.0.1197186072006NANANANANA
rs38660211821692988627BDNFumls:C0011570BeFreeImaging genetics studies have investigated the influence of the serotonin transporter-linked polymorphic region (5HTTLPR) and brain-derived neurotrophic factor (BDNF) Val66Met polymorphism on the hippocampus in healthy individuals and patients with depression (MDD).0.1197186072011NANANANANA
rs386602118231573391312COMTumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0376334072013NANANANANA
rs38660211821143020627BDNFumls:C0011570BeFreeDecreased serum brain-derived neurotrophic factor (BDNF) is associated with post-stroke depression but not with BDNF gene Val66Met polymorphism.0.1197186072011NANANANANA
rs386602118231573394128MAOAumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0328233992013NANANANANA
rs386602118210372136532SLC6A4umls:C0011570BeFreePolymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent depression in at-risk adolescents.0.1546465152010NANANANANA
rs38660211823880378627BDNFumls:C0011570BeFreeThe serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: associations with cognitive vulnerability to depression in childhood.0.1197186072014NANANANANA
rs386602118207288773359HTR3Aumls:C0011570BeFreeWe examined how genetic (brain-derived neurotrophic factor [BDNF] valine 66 to methionine [Val66Met] and serotonin receptor gene 3A [HTR3A]) and early life stress susceptibility factors interact in predicting electroencephalogram (EEG) asymmetry, emotion-elicited heart rate, and self-reported negativity bias, each correlates of risk for depression.0.0058198312010NANANANANA
rs386602118231573393356HTR2Aumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0431058522013NANANANANA
rs38660211820515664627BDNFumls:C0011570BeFreeRecently, a single nucleotide polymorphism (SNP) in the BDNF gene (Val66Met) has been found to be associated with depression and anxiety disorders.0.1197186072010NANANANANA
rs38660211825618300627BDNFumls:C0011570BeFreeWe investigated the effect of brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism on the severity of depressive and anxiety symptoms in never-smokers, former smokers, non-dependent, and nicotine-dependent smokers with a current diagnosis of depression and/or anxiety.0.1197186072014NANANANANA
rs386602118231573395027P2RX7umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0090011892013NANANANANA
rs38660211817632285627BDNFumls:C0011570BeFreeThe brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans.0.1197186072007NANANANANA
rs38660211818548532627BDNFumls:C0011570BeFreeHere, we determined the effects of the BDNF Val66met polymorphism on the five-factor personality dimensions (assessed using the NEO-FFI), trait depression (assessed with the DASS-21) in a cross-sectional cohort of 467 healthy volunteers.0.1197186072009NANANANANA
rs38660211815913870627BDNFumls:C0011570BeFreeAssuming that BDNF may be implicated in the putative common pathophysiology of depression and anxiety, we analyzed the association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (formerly named C270T) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with panic disorder.0.1197186072005NANANANANA
rs38660211820016225627BDNFumls:C0011570BeFreeAssociation of brain-derived neurotrophic factor genetic Val66Met polymorphism with severity of depression, efficacy of fluoxetine and its side effects in Chinese major depressive patients.0.1197186072010NANANANANA
rs38660211823165919627BDNFumls:C0011570BeFreeA brain-derived neurotrophic factor (BDNF) prodomain single-nucleotide polymorphism resulting in a valine to methionine substitution (Val66Met) has been associated with depression-related phenotypes and brain alterations involving regions consistently associated with major depressive disorder (MDD).0.1197186072013NANANANANA
rs38660211820515362627BDNFumls:C0011570BeFreeSix functional SNPs in genes related to the serotonergic system were examined: serotonin transporter (5HTTLPR including rs25531), 5HT1A C-(1019)G and 5HT2A T-(102)C, methylene tetrahydrofolate reductase (MTHFR) C-(677)T, brain-derived neurotrophic factor (BDNF) val66met and tryptophan hydroxylase-2 (TPH2) G-(703)T. Regression analyses were performed using the six SNPs as independent variables: Model 1 with response (percentage Hamilton Depression (HAMD) change from baseline to endpoint) as the dependent variable and Model 2 with adverse event index as the dependent variable (Bonferroni corrected p-value < 0.025).0.1197186072010NANANANANA
rs38660211824745471627BDNFumls:C0011570BeFreeThe brain-derived neurotrophic factor (BDNF) Val66Met single nucleotide polymorphism may be associated with clinical and subsyndromal depression, but physical activity improves mood and increases BDNF expression.0.1197186072014NANANANANA
rs38660211817911362627BDNFumls:C0011570BeFreeAllelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression.0.1197186072007NANANANANA
rs386602118231573391636ACEumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0132683142013NANANANANA
rs38660211818852698627BDNFumls:C0011570BeFreeIn the total sample, the BDNF Val66Met polymorphism was not significantly associated with depression.0.1197186072010NANANANANA
rs386602118231573397166TPH1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0261132972013NANANANANA
rs38660211823968401627BDNFumls:C0011570BeFreeFunctional Val66Met polymorphism of Brain-derived neurotrophic factor in type 2 diabetes with depression in Han Chinese subjects.0.1197186072013NANANANANA
rs386602118231573391394CRHR1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0204453552013NANANANANA
rs38660211820097294627BDNFumls:C0011570BeFreeFurthermore, the sex-specific genotype effects may contribute to sex-specific effects of BDNF Val66Met on depression vulnerability.0.1197186072010NANANANANA
rs38660211823733090627BDNFumls:C0011570BeFreeEEG alpha power as an intermediate measure between brain-derived neurotrophic factor Val66Met and depression severity in patients with major depressive disorder.0.1197186072014NANANANANA
rs386602118179410971312COMTumls:C0011570BeFreeTwo common functional polymorphisms in catechol-O-methyltransferase (COMT Val158Met) and brain-derived neurotrophic factor (BDNF Val66Met) genes have been implicated in the neurobiology of anxiety and depression.0.0376334072008NANANANANA
rs386602118205153623350HTR1Aumls:C0011570BeFreeSix functional SNPs in genes related to the serotonergic system were examined: serotonin transporter (5HTTLPR including rs25531), 5HT1A C-(1019)G and 5HT2A T-(102)C, methylene tetrahydrofolate reductase (MTHFR) C-(677)T, brain-derived neurotrophic factor (BDNF) val66met and tryptophan hydroxylase-2 (TPH2) G-(703)T. Regression analyses were performed using the six SNPs as independent variables: Model 1 with response (percentage Hamilton Depression (HAMD) change from baseline to endpoint) as the dependent variable and Model 2 with adverse event index as the dependent variable (Bonferroni corrected p-value < 0.025).0.0516401022010NANANANANA
rs38660211820515362121278TPH2umls:C0011570BeFreeSix functional SNPs in genes related to the serotonergic system were examined: serotonin transporter (5HTTLPR including rs25531), 5HT1A C-(1019)G and 5HT2A T-(102)C, methylene tetrahydrofolate reductase (MTHFR) C-(677)T, brain-derived neurotrophic factor (BDNF) val66met and tryptophan hydroxylase-2 (TPH2) G-(703)T. Regression analyses were performed using the six SNPs as independent variables: Model 1 with response (percentage Hamilton Depression (HAMD) change from baseline to endpoint) as the dependent variable and Model 2 with adverse event index as the dependent variable (Bonferroni corrected p-value < 0.025).0.0275464512010NANANANANA
rs38660211820220593627BDNFumls:C0011570BeFreeThe brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression.0.1197186072010NANANANANA
rs38660211814673216627BDNFumls:C0011570BeFreeThe genotype and allele frequencies for the BDNF gene Val66Met polymorphism did not differ comparing depression groups (total, bipolar disorder or major depression) and control subjects.0.1197186072003NANANANANA
rs38660227617183148348APOEumls:C0011570BeFreeThe aim of this study was to investigate the role of serotonin in depression, searching for association of two serotoninergic polymorphisms (T102C of serotonin receptor 5-HT2A and serotonin transporter linked polymorphic region -5-HTTLPR- of SLC6A4 gene) with depressive symptoms and considering their possible interactions with Apolipoprotein E (ApoE) and between themselves, in a sample of 208 sporadic AD patients and 116 normal controls from Italy.0.0486106342006NANANANANA
rs386602276231573394128MAOAumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0328233992013NANANANANA
rs386602276239732496532SLC6A4umls:C0011570BeFreeAssociations between suicidal ideation and 5-HTTLPR, STin2 VNTR, 5-HTR2a 1438A/G, and 5-HTR2a 102T/C genotypes were estimated using logistic regression models, and gene-gene interactions were investigated using the generalized multifactor dimensionality reduction method after adjustment for potential covariates, including depression.0.1546465152013NANANANANA
rs386602276117278943356HTR2Aumls:C0011570BeFreeOur results suggest that the 102T/C polymorphism in 5-HT2A receptor gene is primarily associated with suicidal ideation in patients with major depression and not with depression itself.0.0431058522001NANANANANA
rs386602276152323583356HTR2Aumls:C0011570BeFreeThe aim of this study is to investigate whether there were any association between the 102 T/C and -1438 G/A polymorphisms of the 5-HT2A receptor gene and IBS, and abdominal pain, anxiety and depression.0.0431058522004NANANANANA
rs386602276231573395027P2RX7umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0090011892013NANANANANA
rs386602276231573397166TPH1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0261132972013NANANANANA
rs386602276231573391312COMTumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0376334072013NANANANANA
rs386602276231573391394CRHR1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0204453552013NANANANANA
rs386602276231573392289FKBP5umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0180783232013NANANANANA
rs386602276239732493356HTR2Aumls:C0011570BeFreeAssociations between suicidal ideation and 5-HTTLPR, STin2 VNTR, 5-HTR2a 1438A/G, and 5-HTR2a 102T/C genotypes were estimated using logistic regression models, and gene-gene interactions were investigated using the generalized multifactor dimensionality reduction method after adjustment for potential covariates, including depression.0.0431058522013NANANANANA
rs386602276231573393356HTR2Aumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0431058522013NANANANANA
rs386602276171831483356HTR2Aumls:C0011570BeFreeThe aim of this study was to investigate the role of serotonin in depression, searching for association of two serotoninergic polymorphisms (T102C of serotonin receptor 5-HT2A and serotonin transporter linked polymorphic region -5-HTTLPR- of SLC6A4 gene) with depressive symptoms and considering their possible interactions with Apolipoprotein E (ApoE) and between themselves, in a sample of 208 sporadic AD patients and 116 normal controls from Italy.0.0431058522006NANANANANA
rs386602276231573391636ACEumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0132683142013NANANANANA
rs40184181817936531SLC6A3umls:C0011570GAD[Association between polymorphisms in the dopamine transporter gene and depression: evidence for a gene-environment interaction in a sample of juvenile detainees.]0.0237462652008SLC6A351394962CT
rs41305272244362535607MAP2K5umls:C0011570BeFreeA predicted miR-330-3p target site SNP (rs41305272) in mitogen-activated protein kinase kinase 5 (MAP2K5) mRNA was in LD (d' = 1.0, r(2) = 0.02) with a reported GWAS-identified variant for restless legs syndrome (RLS), a disorder frequently comorbid with anxiety and depression, possibly because of a shared pathophysiology.0.0002714422013MAP2K51567807105CT
rs4130527224436253442902MIR330umls:C0011570BeFreeA predicted miR-330-3p target site SNP (rs41305272) in mitogen-activated protein kinase kinase 5 (MAP2K5) mRNA was in LD (d' = 1.0, r(2) = 0.02) with a reported GWAS-identified variant for restless legs syndrome (RLS), a disorder frequently comorbid with anxiety and depression, possibly because of a shared pathophysiology.0.0002714422013MAP2K51567807105CT
rs430574520493543319100TAAR6umls:C0011570BeFreeIn this study we investigated for the first time the possible association between a set of TAAR6 genetic variations (rs7452939; rs4305745; rs6903874; rs6937506; and rs8192625) with clinical features of depression including antidepressant treatment response in a sample of 187 depressive patients all of Korean origins.0.0002714422010NA6132572573GA
rs46589662148343027185DISC1umls:C0011570BeFreeCognitive measures of working memory (rs2793094, P=3.38 × 10(-4)), as well as lifetime history of depression (rs4658966, P=4.33 × 10(-4); rs12137417, P=4.93 × 10(-4)) and panic (rs12137417, P=7.41 × 10(-4)) were associated with DISC1 sequence variation.0.0077199252011DISC1;TSNAX-DISC1;DISC1-IT11231942868TC
rs4675690206434831385CREB1umls:C0011570BeFreeOne hundred-ninety MD patients collected in the context of a resistant depression study and treated with antidepressants for at least 4weeks were genotyped for 5 CREB1 SNPs (rs2709376, rs2253206, rs7569963, rs7594560, and rs4675690).0.0119111052011NA2207643083CT
rs4680231573391312COMTumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0376334072013COMT;MIR47612219963748GA
rs4680179410971312COMTumls:C0011570BeFreeTwo common functional polymorphisms in catechol-O-methyltransferase (COMT Val158Met) and brain-derived neurotrophic factor (BDNF Val66Met) genes have been implicated in the neurobiology of anxiety and depression.0.0376334072008COMT;MIR47612219963748GA
rs4680231573391394CRHR1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0204453552013COMT;MIR47612219963748GA
rs4680246793921312COMTumls:C0011570BeFreeThe present study investigated the effects of familial risk for depression and the 5-HTTLPR and COMT Val158Met polymorphisms, which have been associated with risk for depression, on biases in endorsement of and memory for positive and negative adjectives.0.0376334072014COMT;MIR47612219963748GA
rs4680206196114858NOVA2umls:C0011570BeFreeChanges in severity of depression were assessed with weekly Hamilton Depression ratings and analyzed with repeated measures ANOVA in the context of General Linear Model, with rs4680 and fluvoxamine plasma levels as factors.0.0008143262010COMT;MIR47612219963748GA
rs4680246793926532SLC6A4umls:C0011570BeFreeThe present study investigated the effects of familial risk for depression and the 5-HTTLPR and COMT Val158Met polymorphisms, which have been associated with risk for depression, on biases in endorsement of and memory for positive and negative adjectives.0.1546465152014COMT;MIR47612219963748GA
rs4680188280351312COMTumls:C0011570BeFreeThe Met allele of the Catechol-O-Methyltransferase (COMT) gene functional polymorphism (COMT-V158M) is associated with lower enzymatic activity than the Val allele and is reported to be associated with aggression, depression, and suicidal behavior.0.0376334072008COMT;MIR47612219963748GA
rs4680231573392289FKBP5umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0180783232013COMT;MIR47612219963748GA
rs4680175226261312COMTumls:C0011570BeFreeIn the present study, 256 patients with major depression (DSM-IV) of Caucasian descent were genotyped for the functional COMT val158met polymorphism and characterized for clinical response to antidepressive pharmacological treatment as measured by intra-individual changes of Hamilton Depression (HAM-D-21) scores over 6 weeks.0.0376334072008COMT;MIR47612219963748GA
rs4680231573395027P2RX7umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0090011892013COMT;MIR47612219963748GA
rs4680231573391636ACEumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0132683142013COMT;MIR47612219963748GA
rs4680231573393356HTR2Aumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0431058522013COMT;MIR47612219963748GA
rs4680208288311312COMTumls:C0011570BeFreeThe functional Val158Met polymorphism in catechol-O-methyltransferase (COMT) is associated with depression and motivation in men from a Swedish population-based study.0.0376334072011COMT;MIR47612219963748GA
rs4680231573397166TPH1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0261132972013COMT;MIR47612219963748GA
rs468017941097627BDNFumls:C0011570BeFreeTwo common functional polymorphisms in catechol-O-methyltransferase (COMT Val158Met) and brain-derived neurotrophic factor (BDNF Val66Met) genes have been implicated in the neurobiology of anxiety and depression.0.1197186072008COMT;MIR47612219963748GA
rs4680220442411312COMTumls:C0011570BeFreeOur objectives were (1) to examine how baseline stress and change in stress is associated with course of geriatric depression and (2) to test whether polymorphisms of serotonin transporter (5-HTTLPR) and catechol-O-methyltransferase (COMT Val158Met) genes moderate this relation.0.0376334072012COMT;MIR47612219963748GA
rs4680231573394128MAOAumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0328233992013COMT;MIR47612219963748GA
rs4680223871741312COMTumls:C0011570BeFreeThe present results provide further support for a-potentially female-specific-role of the COMT val158met polymorphism in the genetic and neural underpinnings of anxiety- and depression-related intermediate phenotypes and may aid in further clarifying the differential role of COMT genotype driven dopaminergic tonus in the processing of emotionally salient stimuli.0.0376334072012COMT;MIR47612219963748GA
rs4906902220826592562GABRB3umls:C0011570BeFreeThe rs4906902 G allele of the GABRB3 gene was overrepresented in mTLE patients with depression; individuals homozygous for the G allele showed reduced GABRB3 mRNA expression.0.0008143262011GABRB31526774621AG
rs4986938218041482100ESR2umls:C0011570BeFreeIn men, only the ER-β rs4986938 polymorphism showed a weak association with depression risk.0.0008143262011ESR21464233098CT
rs53576247031665021OXTRumls:C0011570BeFreeOxytocin receptor gene polymorphism (rs53576) moderates the intergenerational transmission of depression.0.0039956832014OXTR38762685AG
rs5443168975962784GNB3umls:C0011570BeFreeThe GNB3 C825T polymorphism and depression among subjects with alcohol dependence.0.0102824542007GNB3;CDCA3126845711CT
rs5443217096002784GNB3umls:C0011570BeFreeThe GNB3 C825T polymorphism as a pharmacogenetic marker in the treatment of hypertension, obesity, and depression.0.0102824542011GNB3;CDCA3126845711CT
rs5522211642674306NR3C2umls:C0011570BeFreeIn an elderly cohort, one of the functional MR gene variants, MR-I180V, associated with higher feelings of depression.0.0021715352011NR3C24148436323CT
rs5558191052003350HTR1Aumls:C0011570BeFreeIn conclusion, our results favor the hypothesis that monoaminergic neurotransmission in general and the F528C NET and R219L 5-HT(1A) receptor variants in particular are involved in the pathogenesis of depression.0.0516401022009SLC6A21655699647TG
rs5558191052006530SLC6A2umls:C0011570BeFreeIn conclusion, our results favor the hypothesis that monoaminergic neurotransmission in general and the F528C NET and R219L 5-HT(1A) receptor variants in particular are involved in the pathogenesis of depression.0.0192836432009SLC6A21655699647TG
rs5569227277091312COMTumls:C0011570BeFreeIn self-identified white patients with major depressive disorder (N=126) treated with open-label duloxetine (60-120 mg/d), a significant association of (P=0.020) of a composite risk score (based on SLC6A2 rs5569 [G1287A] AA, HTR1A rs6295 [C(-1019)G] GG, and COMT rs174697 AA/AG) with 17-item Hamilton Depression Rating Scale total score change from baseline to 12 weeks was observed.0.0376334072012SLC6A21655697923GC,A
rs561424421984420655729ATF7IPumls:C0011570BeFreeAfter controlling for age, gender and baseline 21-item Hamilton Depression Rating Scale (HAM-D21) score, as well as correcting for multiple testing, the relative reduction of HAM-D21 score remained significantly associated with two NTRK2-coding SNPs (rs2289657 and rs56142442) and the haplotype CAG at rs2289658 (splice site), rs2289657 and rs2289656.0.0027144192009NTRK2985021350CT
rs5616441524047966627BDNFumls:C0011570BeFreeTherefore, we examined whether a single-nucleotide polymorphism in the BDNF gene (rs56164415) and related receptors TrkB (rs1212171) and p75 (rs2072446) were associated with depression in HIV-infected individuals.0.1197186072013BDNF1127700188GA
rs56164415240479667133TNFRSF1Bumls:C0011570BeFreeTherefore, we examined whether a single-nucleotide polymorphism in the BDNF gene (rs56164415) and related receptors TrkB (rs1212171) and p75 (rs2072446) were associated with depression in HIV-infected individuals.0.0005428842013BDNF1127700188GA
rs6188880023532066627BDNFumls:C0011570BeFreeThe aim of the present study was to test for a possible association between two brain-derived neurotrophic factor (BDNF) polymorphisms (rs11030101 and rs61888800) and the efficacy of electroconvulsive therapy (ECT) [change in Montgomery-Åsberg Depression Rating Scale (MADRS)].0.1197186072013BDNF1127700731GT
rs626519236730627BDNFumls:C0011570BeFreeHowever, BDNF rs7103411 and rs6265 similarly predicted worse treatment response over 6 wk in clinical subtypes of depression such as melancholic depression only (rs7103411: TT < CC, p = 0.003; rs6265: GG < AA, p = 0.001).0.1197186072010BDNF;BDNF-AS1127658369CT
rs626517632285627BDNFumls:C0011570BeFreeThe brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans.0.1197186072007BDNF;BDNF-AS1127658369CT
rs626521188787627BDNFumls:C0011570BeFreeTwo hundred and six patients with Diagnostic and Statistical Manual of Mental Disorders-IV MDD were recruited for this study and genotyped for eight BDNF tagging SNPs (rs11030096, rs925946, rs10501087,rs6265, rs12273363, rs908867, rs1491850, and rs1491851)to investigate the functional impact of genotypes/haplotypes in the susceptibility of depression and on treatment response.0.1197186072011BDNF;BDNF-AS1127658369CT
rs626521577214627BDNFumls:C0011570BeFreeGiven that BDNF secretion is affected by a common polymorphism (rs6265, Val66Met), which also is associated with depression, we investigated whether this polymorphism modifies the effect of childhood adversity (CA) on local gray matter (GM) volume in depression-relevant brain regions, using data from two large cohorts of healthy subjects.0.1197186072012BDNF;BDNF-AS1127658369CT
rs626525998702627BDNFumls:C0011570BeFreeA genetic variant (rs6265) of the brain-derived neurotrophic factor (BDNF) impacting on emotion processing is known to increase the risk for depression.0.1197186072015BDNF;BDNF-AS1127658369CT
rs626521215389627BDNFumls:C0011570BeFreeFinally, using functional magnetic resonance imaging, we found that viewing sad faces evoked greater activity in depression-related areas in healthy control subjects possessing the minor alleles of BDNF-rs6265 and CREB1-rs2253206.0.1197186072011BDNF;BDNF-AS1127658369CT
rs6265212153891385CREB1umls:C0011570BeFreeFinally, using functional magnetic resonance imaging, we found that viewing sad faces evoked greater activity in depression-related areas in healthy control subjects possessing the minor alleles of BDNF-rs6265 and CREB1-rs2253206.0.0119111052011BDNF;BDNF-AS1127658369CT
rs6295213979533350HTR1Aumls:C0011570BeFreeIn humans, the G variant of the C(-1019)G 5-HT1A receptor promoter gene polymorphism (rs6295) has been associated with higher expression of 5-HT1A receptors, increased depression, and lower stress preceding completed suicide.0.0516401022011HTR1A563962738CG
rs6295260016683439IFNA1umls:C0011570BeFreeHistory of mood disorders and HTR1A G allele variation, the C-1019G polymorphism of the transcriptional control region of the 5-HT1A receptor, independently predicted the incidence of IFN-induced depression in HCV patients, whether separately or jointly considered and although not reciprocally associated.0.0008143262015HTR1A563962738CG
rs6295215770073350HTR1Aumls:C0011570BeFreeThe current study aimed to investigate the interaction between the serotonin 1A receptor gene (HTR1A) C-1019G polymorphism and recent negative life stressors on depression in a Korean community sample.0.0516401022011HTR1A563962738CG
rs6295242743733350HTR1Aumls:C0011570BeFreeThe 5-HT2A A-1438G, 5-HT2A T102C, BDNF Val66Met, and 5-HT1A C-1019G gene polymorphisms might predict the incidence of depression with ABB.0.0516401022013HTR1A563962738CG
rs6295227277091312COMTumls:C0011570BeFreeIn self-identified white patients with major depressive disorder (N=126) treated with open-label duloxetine (60-120 mg/d), a significant association of (P=0.020) of a composite risk score (based on SLC6A2 rs5569 [G1287A] AA, HTR1A rs6295 [C(-1019)G] GG, and COMT rs174697 AA/AG) with 17-item Hamilton Depression Rating Scale total score change from baseline to 12 weeks was observed.0.0376334072012HTR1A563962738CG
rs6295260016683447IFNA13umls:C0011570BeFreeHistory of mood disorders and HTR1A G allele variation, the C-1019G polymorphism of the transcriptional control region of the 5-HT1A receptor, independently predicted the incidence of IFN-induced depression in HCV patients, whether separately or jointly considered and although not reciprocally associated.0.0008143262015HTR1A563962738CG
rs6295232692153350HTR1Aumls:C0011570BeFreeResults also confirm the mediating role of impulsivity between the SNP rs6295 of HTR1A and depression.0.0516401022012HTR1A563962738CG
rs6295260016683350HTR1Aumls:C0011570BeFreeHistory of mood disorders and HTR1A G allele variation, the C-1019G polymorphism of the transcriptional control region of the 5-HT1A receptor, independently predicted the incidence of IFN-induced depression in HCV patients, whether separately or jointly considered and although not reciprocally associated.0.0516401022015HTR1A563962738CG
rs6313188014063356HTR2Aumls:C0011570BeFree5-HT2A receptor gene polymorphism rs6313 was associated with 5-HT2A receptor binding potential, with the ability of individuals to use environmental support in order to prevent depression, and with sleep improvement after antidepressant treatment with mirtazapine.0.0431058522008HTR2A1346895805GA
rs6313231573391394CRHR1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0204453552013HTR2A1346895805GA
rs6313231573392289FKBP5umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0180783232013HTR2A1346895805GA
rs6313231573391312COMTumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0376334072013HTR2A1346895805GA
rs6313239732493356HTR2Aumls:C0011570BeFreeAssociations between suicidal ideation and 5-HTTLPR, STin2 VNTR, 5-HTR2a 1438A/G, and 5-HTR2a 102T/C genotypes were estimated using logistic regression models, and gene-gene interactions were investigated using the generalized multifactor dimensionality reduction method after adjustment for potential covariates, including depression.0.0431058522013HTR2A1346895805GA
rs6313231573394128MAOAumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0328233992013HTR2A1346895805GA
rs6313231573393356HTR2Aumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0431058522013HTR2A1346895805GA
rs6313171831483356HTR2Aumls:C0011570BeFreeThe aim of this study was to investigate the role of serotonin in depression, searching for association of two serotoninergic polymorphisms (T102C of serotonin receptor 5-HT2A and serotonin transporter linked polymorphic region -5-HTTLPR- of SLC6A4 gene) with depressive symptoms and considering their possible interactions with Apolipoprotein E (ApoE) and between themselves, in a sample of 208 sporadic AD patients and 116 normal controls from Italy.0.0431058522006HTR2A1346895805GA
rs6313117278943356HTR2Aumls:C0011570BeFreeOur results suggest that the 102T/C polymorphism in 5-HT2A receptor gene is primarily associated with suicidal ideation in patients with major depression and not with depression itself.0.0431058522001HTR2A1346895805GA
rs631317183148348APOEumls:C0011570BeFreeThe aim of this study was to investigate the role of serotonin in depression, searching for association of two serotoninergic polymorphisms (T102C of serotonin receptor 5-HT2A and serotonin transporter linked polymorphic region -5-HTTLPR- of SLC6A4 gene) with depressive symptoms and considering their possible interactions with Apolipoprotein E (ApoE) and between themselves, in a sample of 208 sporadic AD patients and 116 normal controls from Italy.0.0486106342006HTR2A1346895805GA
rs6313152323583356HTR2Aumls:C0011570BeFreeThe aim of this study is to investigate whether there were any association between the 102 T/C and -1438 G/A polymorphisms of the 5-HT2A receptor gene and IBS, and abdominal pain, anxiety and depression.0.0431058522004HTR2A1346895805GA
rs6313231573395027P2RX7umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0090011892013HTR2A1346895805GA
rs6313231573391636ACEumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0132683142013HTR2A1346895805GA
rs6313231573397166TPH1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0261132972013HTR2A1346895805GA
rs6313239732496532SLC6A4umls:C0011570BeFreeAssociations between suicidal ideation and 5-HTTLPR, STin2 VNTR, 5-HTR2a 1438A/G, and 5-HTR2a 102T/C genotypes were estimated using logistic regression models, and gene-gene interactions were investigated using the generalized multifactor dimensionality reduction method after adjustment for potential covariates, including depression.0.1546465152013HTR2A1346895805GA
rs6354195412926532SLC6A4umls:C0011570BeFreeWe found evidence for association (p = .0062, after accounting for multiple testing) for SLC6A4 SNPs rs6354 and rs2020936 (positioned in a different linkage disequilibrium [LD] block about 15.5 kb from 5HTTLPR) with anxiety and/or depression and neuroticism, with the strongest association for recurrent depression with onset in young adulthood (odds ratio = 1.55, 95% confidence interval = 1.16-2.06).0.1546465152009SLC6A41730222880GT
rs6491292016757828ABOumls:C0011570GAD[Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels.]0.0023670322010NA9133278860TG,C
rs662171830215444PON1umls:C0011570BeFreeThe association of the paraoxonase (PON1) Q192R polymorphism with depression in older women: findings from the British Women's Heart and Health Study.0.0031813582007PON1795308134TC
rs669110587892A2Mumls:C0011570BeFreeIn the present study we tested two polymorphisms in the alpha-2 macroglobulin gene, a 5 bp deletion at the 5' splice site of exon 18 and a G/A point mutation (V1000I) in exon 24, in a sample of 118 healthy, non demented controls and 238 consecutively recruited gerontopsychiatric patients, diagnosed as: Alzheimer's disease (N=88), mild cognitive impairment (N=32), subjective cognitive complaints (N=54) and depression/other psychiatric disorders (N=64).0.0005428842000A2M129079672TC
rs690387420493543319100TAAR6umls:C0011570BeFreeIn this study we investigated for the first time the possible association between a set of TAAR6 genetic variations (rs7452939; rs4305745; rs6903874; rs6937506; and rs8192625) with clinical features of depression including antidepressant treatment response in a sample of 187 depressive patients all of Korean origins.0.0002714422010NA6132575771TC
rs693750620493543319100TAAR6umls:C0011570BeFreeIn this study we investigated for the first time the possible association between a set of TAAR6 genetic variations (rs7452939; rs4305745; rs6903874; rs6937506; and rs8192625) with clinical features of depression including antidepressant treatment response in a sample of 187 depressive patients all of Korean origins.0.0002714422010NA6132578260GA
rs710341119236730627BDNFumls:C0011570BeFreeHowever, BDNF rs7103411 and rs6265 similarly predicted worse treatment response over 6 wk in clinical subtypes of depression such as melancholic depression only (rs7103411: TT < CC, p = 0.003; rs6265: GG < AA, p = 0.001).0.1197186072010BDNF;BDNF-AS1127678578CT
rs730511520738857121278TPH2umls:C0011570GAD[The study suggested that hopelessness, negative life events and family history of suicide were risk factors of attempted suicide in MDD while the TPH2 rs7305115A remained a significant protective predictor of suicide attempts.]0.0275464512010TPH21271979082AG
rs74421874246481625715PSMD9umls:C0011570BeFreePSMD9 SNP rs74421874 [intervening sequence (IVS) 3 + nt460 G>A], rs3825172 (IVS3 + nt437 C>T) and rs1043307/rs2514259 (E197G A>G) are all linked to type 2 diabetes (T2D), maturity-onset-diabetes-of the young 3 (MODY3), obesity and waist circumference, hypertension, hypercholesterolemia, T2D-macrovascular and T2D-microvascular disease, T2D-neuropathy, T2D-carpal tunnel syndrome, T2D-nephropathy, T2D-retinopathy, non-diabetic retinopathy and depression.0.0029099162014PSMD912121902546GA
rs745293920493543319100TAAR6umls:C0011570BeFreeIn this study we investigated for the first time the possible association between a set of TAAR6 genetic variations (rs7452939; rs4305745; rs6903874; rs6937506; and rs8192625) with clinical features of depression including antidepressant treatment response in a sample of 187 depressive patients all of Korean origins.0.0002714422010NANANANANA
rs7486220201746234582MUC1umls:C0011570BeFreeWe found significant association between TIMELESS variants and depression with fatigue (D+FAT+) (rs7486220: pointwise P = 0.000099, OR = 1.66; corrected empirical P for the model of D+FAT+ = 0.0056; haplotype 'C-A-A-C' of rs2291739-rs2291738-rs7486220-rs1082214: P = 0.0000075, OR = 1.72) in females, and association to depression with early morning awakening (D+EMA+) (rs1082214: pointwise P = 0.0009, OR = 2.70; corrected empirical P = 0.0374 for the model D+EMA+; haplotype 'G-T' of rs7486220 and rs1082214: P = 0.0001, OR = 3.01) in males.0.0002714422010NANANANANA
rs748622020174623948CD36umls:C0011570BeFreeWe found significant association between TIMELESS variants and depression with fatigue (D+FAT+) (rs7486220: pointwise P = 0.000099, OR = 1.66; corrected empirical P for the model of D+FAT+ = 0.0056; haplotype 'C-A-A-C' of rs2291739-rs2291738-rs7486220-rs1082214: P = 0.0000075, OR = 1.72) in females, and association to depression with early morning awakening (D+EMA+) (rs1082214: pointwise P = 0.0009, OR = 2.70; corrected empirical P = 0.0374 for the model D+EMA+; haplotype 'G-T' of rs7486220 and rs1082214: P = 0.0001, OR = 3.01) in males.0.0002714422010NANANANANA
rs75634836231573392289FKBP5umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0180783232013HTR2A1346835532CA,T
rs75634836231573395027P2RX7umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0090011892013HTR2A1346835532CA,T
rs75634836231573394128MAOAumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0328233992013HTR2A1346835532CA,T
rs75634836231573393356HTR2Aumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0431058522013HTR2A1346835532CA,T
rs75634836231573391394CRHR1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0204453552013HTR2A1346835532CA,T
rs75634836231573391312COMTumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0376334072013HTR2A1346835532CA,T
rs75634836231573391636ACEumls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0132683142013HTR2A1346835532CA,T
rs75634836231573397166TPH1umls:C0011570BeFreeTo investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.0.0261132972013HTR2A1346835532CA,T
rs7569963206434831385CREB1umls:C0011570BeFreeOne hundred-ninety MD patients collected in the context of a resistant depression study and treated with antidepressants for at least 4weeks were genotyped for 5 CREB1 SNPs (rs2709376, rs2253206, rs7569963, rs7594560, and rs4675690).0.0119111052011METTL21A2207608460GA
rs7594560206434831385CREB1umls:C0011570BeFreeOne hundred-ninety MD patients collected in the context of a resistant depression study and treated with antidepressants for at least 4weeks were genotyped for 5 CREB1 SNPs (rs2709376, rs2253206, rs7569963, rs7594560, and rs4675690).0.0119111052011NA2207641155TC
rs7607612082237284062DTNBP1umls:C0011570BeFreeTwo intronic SNPs of DTNBP1; rs760761 (P1320) and rs2619522 (P1763) were analyzed in 206 patients with DSM-IV MDD to investigate the functional impact of genotypes on susceptibility for depression and some clinical phenotypes.0.0079154222010DTNBP1615650901GA
rs7997012235377813356HTR2Aumls:C0011570BeFreeThe HTR2A-rs7997012 is worthy of further investigation in studies examining factors that are related to depression course and outcome.0.0431058522013HTR2A1346837850AG
rs819262520493543319100TAAR6umls:C0011570BeFreeIn this study we investigated for the first time the possible association between a set of TAAR6 genetic variations (rs7452939; rs4305745; rs6903874; rs6937506; and rs8192625) with clinical features of depression including antidepressant treatment response in a sample of 187 depressive patients all of Korean origins.0.0002714422010TAAR66132571193GA
rs90886721188787627BDNFumls:C0011570BeFreeTwo hundred and six patients with Diagnostic and Statistical Manual of Mental Disorders-IV MDD were recruited for this study and genotyped for eight BDNF tagging SNPs (rs11030096, rs925946, rs10501087,rs6265, rs12273363, rs908867, rs1491850, and rs1491851)to investigate the functional impact of genotypes/haplotypes in the susceptibility of depression and on treatment response.0.1197186072011NA1127724217CT
rs92594621188787627BDNFumls:C0011570BeFreeTwo hundred and six patients with Diagnostic and Statistical Manual of Mental Disorders-IV MDD were recruited for this study and genotyped for eight BDNF tagging SNPs (rs11030096, rs925946, rs10501087,rs6265, rs12273363, rs908867, rs1491850, and rs1491851)to investigate the functional impact of genotypes/haplotypes in the susceptibility of depression and on treatment response.0.1197186072011BDNF-AS1127645655TG
rs9340799218041482099ESR1umls:C0011570BeFreeIn women, the ER-α rs2234693 and rs9340799 polymorphisms were significantly associated with the risk of late-life depression.0.0010857672011ESR16151842246AG
rs94726717029202267012DAOAumls:C0011570GAD[Association between depression and G72 gene polymorphism.]0.0073725382006DAOA;DAOA-AS113105487313TG
rs9722194971636285S100Bumls:C0011570BeFreeSignificant differences in the subgroup depression (first-episode and recurrent depression) were also shown in 3 genotypes of S100B rs9722 and rs11911834 in patients and control subjects (P < 0.05).0.0010857672009S100B2146599326GA
rs99396092316481779068FTOumls:C0011570BeFreeThe protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression.0.0010857672012FTO1653786615TA
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:6171)
CHR POS SNPID REF ALT ORI_SNPID PMID P_VALUE P_VALUE_TEXT OR/BETA CI95_TEXT GWAS_INITIAL_SAMPLE_SIZE SUB_POPULATION SUPER_POPULATION GWAS_TRAIT HPO_ID HPO_TERM DO_ID DO_TERM MESH_ID MESH_TERM EFO_ID EFO_TERM DOLITE_TERM RISK_ALLELE PUBLICATION_TYPE AA GENE_SYMBOL TYPE REFGENE
12883858rs2485944CTrs2485944224728767.27E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
15354844rs912988CTrs912988233776406.00E-06% improvement - SSRI treated - 2 weeks0.18[0.1-0.26] unit increaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs912988-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
17478076rs11120917CTrs11120917240474461.45E-05(Quantitative)0.44[NA] unit decrease1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs11120917-T
17727854rs1891215TCrs1891215220471847.64E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
17728391rs1891216TGrs1891216220471849.66E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
17735950rs6661392CTrs6661392220471841.37E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC,T
17736097rs6673977AGrs6673977220471841.37E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
18302619rs7513908GArs7513908210423171.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
19151325rs12080794CTrs12080794237266689.00E-06NA1.75[1.33-2.27]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
19432911rs17393334GArs17393334191071151.45E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
112018290rs2273289TCrs2273289229153520.000000129NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<15HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTPLOD1
112018290rs2273289TCrs2273289229153520.000000448NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<20HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTPLOD1
112018290rs2273289TCrs2273289229153520.00000134NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<35HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTPLOD1
112018290rs2273289TCrs2273289229153520.00000392NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<25HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTPLOD1
112018290rs2273289TCrs2273289229153520.00000436NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<30HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTPLOD1
112018290rs2273289TCrs2273289240474463.19E-05NA1.41NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs2273289-C
112319994rs235243GTrs235243216212699.55E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATVPS13D
113949087rs17390405GArs17390405208002216.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
114370368rs6662320AGrs6662320210423177.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
114385135rs10737918AGrs10737918210423178.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
114390137rs10733143AGrs10733143210423177.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
114680899rs4113453GArs4113453216212699.33E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
117573439rs2977225TCrs2977225229077300.000213NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
118487906rs17435018CTrs17435018198460672.01E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCIGSF21
118490061rs4920300CTrs4920300229077300.0001343NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
120413887rs10916705CGrs10916705208002218.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
120416794rs11573288CTrs11573288208002219.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
121664475rs3026815CTrs3026815208002211.77E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
121678600rs213006TGrs213006208002212.00E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
122345093rs3117048AGrs3117048224728768.28E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
122345647rs2501299CTrs2501299224728765.47E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
124281021rs7521571GArs7521571229077300.0001089NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
124379601rs4649163TCrs4649163229077300.000047NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
124379601rs4649163TCrs4649163229077300.0002016NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
124395575rs4649171AGrs4649171229077300.0001247NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
124412447rs4276861TCrs4276861229077300.000141NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
125434242rs803313TCrs803313216212698.23E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
126721287rs12722898GArs12722898229077300.0000728NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
126721287rs12722898GArs12722898229077300.0001126NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
130410502rs4949232ACrs4949232224728761.98E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
130414182rs16833076TGrs16833076224728763.02E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
130415026rs1498243GArs1498243224728763.89E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
130422596rs4949238AGrs4949238224728763.20E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
130426014rs12407717CTrs12407717210423174.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
130426014rs12407717CTrs12407717224728761.20E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
130439760rs12401298AGrs12401298224728763.95E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
130459797rs4949241GArs4949241224728769.93E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
131647583rs11577241GCrs11577241208002212.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
131650749rs2066163AGrs2066163208002212.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
131653988rs4949356AGrs4949356208002212.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
131658678rs6425715AGrs6425715208002212.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
131659496rs6693735CGrs6693735208002215.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
131673263rs2377717CTrs2377717208002217.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
131676938rs4949197AGrs4949197208002219.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
131682312rs10798827TGrs10798827208002218.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
131683500rs10753244AGrs10753244208002216.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
131683890rs10798828CTrs10798828208002217.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
131686085rs12033154AGrs12033154208002216.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
137250088rs11801494CTrs11801494230914230.0002NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
141026749rs1999822GArs1999822197363533.00E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
141107699rs1534955CGrs1534955208002218.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
141115608rs2780944CTrs2780944208002214.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
141115671rs12728027TCrs12728027208002214.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
141115671rs200548994TGTrs12728027208002214.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
141117899rs10458576GArs10458576208002214.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
141130424rs4332353GArs4332353208002214.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
141154407rs965949GArs965949224728769.17E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
142270666rs16828722CTrs16828722224728765.63E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
143955148rs6429604AGrs6429604208002211.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143957515rs6687571GArs6687571208002211.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143959942rs7417538GArs7417538208002211.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143960479rs2039529AGrs2039529208002217.57E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143960530rs2039528AGrs2039528208002217.25E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143970956rs6675341CTrs6675341208002211.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143974489rs10749849GArs10749849208002211.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143975238rs1413937GArs1413937208002211.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143976266rs10890251ACrs10890251208002213.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143978837rs11210858TCrs11210858208002213.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143979782rs11210859GArs11210859208002213.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143981265rs1413938CTrs1413938208002213.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143981961rs2367617AGrs2367617208002213.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143984142rs11210862CTrs11210862208002213.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143984627rs1413939GCrs1413939208002211.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143985678rs11210863CTrs11210863208002213.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143991832rs11210864GArs11210864208002214.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143992893rs11577317AGrs11577317208002214.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
143999120rs11590627TCrs11590627208002212.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
144974796rs12138940AGrs12138940240474462.50E-05(Dichotomous)1.51NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs12138940-G
147918821rs527430GArs527430220414584.00E-07Citalopram+Buspirone, General SENANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers527430-G
148019222rs17420782AGrs17420782240474469.00E-06(Quantitative)0.55[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs17420782-G
148046320rs2507007GTrs2507007210423172.40E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
149396989rs1343432GCrs1343432224728761.82E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
150937848rs3827730TCrs3827730220641624.00E-06NA1.72[1.36-2.16] 467 European ancestry cases; 407 European ancestry controlsEuropean(874)ALL(874)EUR(874)ALL(874)Depression and alcohol dependenceHPOID:0000716DepressionDOID:303DOID:1596substance-related disordermental depressionD003863DepressionNANADepressionDrug abuseNA
154777562rs11206329AGrs11206329200389476.31E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG,A
154779243rs7524749GArs7524749200389476.34E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
154883163rs4244644CTrs4244644198460679.65E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tTNA
154888245rs4927107ACrs4927107198460673.85E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
155811215rs207138CTrs207138229077300.0001842NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
156802112rs11206793ATrs11206793208002218.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
156804358rs12079898GArs12079898208002217.34E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
156829396rs17113792AGrs17113792208002217.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
156840459rs17113795TArs17113795208002217.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
156844652rs17113799TCrs17113799208002215.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
156845274rs7539724AGrs7539724208002215.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
156851200rs11206802GArs11206802208002214.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
156852348rs4373790CTrs4373790208002214.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
157317559rs10489623AGrs10489623200389477.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
157319629rs1329449GArs1329449200389478.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
157336775rs2269119GCrs2269119200389479.78E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
157340381rs1885002AGrs1885002200389471.71E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
157349407rs6694643ATrs6694643200389476.23E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
157349464rs6697228TCrs6697228200389479.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
157356476rs6683663AGrs6683663200389475.69E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
157362007rs11206932TArs11206932200389476.27E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
157362787rs3768215CTrs3768215200389476.89E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
158514090rs17131774AGrs17131774216212696.98E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGDAB1
159055724rs17117889AGrs17117889208002212.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159107652rs232899GArs232899208002212.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159108799rs232895CTrs232895208002212.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159109001rs232894TCrs232894208002212.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159110018rs232892CTrs232892208002212.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159110502rs232891CTrs232891208002214.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159112057rs232885CArs232885208002212.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159113033rs232882GArs232882208002212.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159114347rs17117956TC,Grs17117956208002212.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159115781rs232876CTrs232876208002212.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159118656rs232874TGrs232874208002212.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159119072rs232871AGrs232871208002212.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159120563rs232860AGrs232860208002212.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159125683rs232777CTrs232777208002212.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159127207rs232780TCrs232780208002212.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159127936rs6587835GArs6587835208002212.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159128237rs232782GArs232782208002212.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159130229rs232786ACrs232786208002212.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159130407rs232787CTrs232787208002212.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159133024rs232794TGrs232794208002212.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159133268rs232795AGrs232795208002212.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159174026rs4912202GArs4912202208002212.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159186777rs11583201GArs11583201208002216.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159190140rs12747063CArs12747063208002217.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159191545rs12405774GArs12405774208002218.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159197556rs7524931GCrs7524931208002218.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
159572316rs1114505TCrs1114505208002216.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
160962168rs4915695AGrs4915695213168601.70E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
160986573rs12138423GArs12138423224728767.53E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
160998195rs10889182TGrs10889182224728766.94E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
161006050rs10889184GArs10889184224728767.33E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
161007182rs11207633AGrs11207633224728764.65E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
161010758rs10889187GArs10889187224728764.44E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
161042598rs1381171TCrs1381171224728761.79E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
161056625rs1572358TCrs1572358224728761.86E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
161895257rs6587924CArs6587924200389478.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
161897967rs2207790GArs2207790200389479.49E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
162130167rs6694023AGrs6694023216212697.90E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
168561012rs269340TCrs269340224728762.28E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
168567418rs9436797GArs9436797229077300.0000481NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
170715093rs3767206GArs3767206220599354.52E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
172874258rs12406365GArs12406365200389474.36E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
173652122rs4650199TCrs4650199230914230.000000598NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173655821rs11210177AGrs11210177230914230.000000759NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173658085rs12069039GCrs12069039230914230.00000119NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173658507rs7514832ATrs7514832230914230.00000111NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173662169rs10890018AGrs10890018230914230.00000114NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173664563rs7522520CTrs7522520230914230.00000124NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173665844rs4650201AGrs4650201230914230.00000103NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173706449rs6684841AGrs6684841230914230.000000251NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173706449rs6684841AGrs6684841230914230.00000154NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173715233rs11210187TCrs11210187230914230.000000597NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173720577rs4650206TCrs4650206230914230.00000062NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173736562rs4571923GArs4571923230914230.00000113NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173743873rs11210193AGrs11210193230914230.000000897NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173743873rs11210193AGrs11210193230914230.00000184NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173755529rs7549372AGrs7549372230914230.000000459NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173755529rs7549372AGrs7549372230914230.000000833NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173814159rs10789368AGrs10789368230914230.00000282NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173849655rs11210220TGrs11210220224728766.55E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173849687rs11210222TCrs11210222224728768.57E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173866020rs1885251GTrs1885251230914230.000000233NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173878194rs11210235TCrs11210235230914230.000000257NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173880654rs10465868AGrs10465868230914230.000000243NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173890390rs7521446TCrs7521446230914230.000000188NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173897809rs11210242CTrs11210242230914230.000000393NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173910055rs4113050TCrs4113050230914230.000000611NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173912799rs11210251CGrs11210251230914230.00000041NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173930405rs505725CArs505725230914230.00000328NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173930493rs622421AGrs622421230914230.00000498NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173931737rs11210255GArs11210255230914230.0000022NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173938246rs17570390TCrs17570390216212695.29E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
173939898rs12754690CTrs12754690230914230.00000188NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173944277rs1578022CGrs1578022231494480.0000593NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
173964312rs11210266GTrs11210266230914230.00000404NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
175240211rs17095902AGrs17095902224728769.70E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
176464725rs12731410CArs12731410208002219.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
177015113rs172714TCrs172714208002215.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
177016065rs6675095GArs6675095208002213.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
177121319rs12134580TCrs12134580232901967.52E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
179238015rs4650608TCrs4650608224728768.49E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
179836598rs12027718CTrs12027718200389472.40E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
179839129rs11811462AGrs11811462200389472.36E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
179847236rs3015033GArs3015033200389472.27E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
179851769rs3015042CTrs3015042200389472.20E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
179853343rs3015046GArs3015046200389472.13E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
179853708rs3015049GArs3015049200389472.10E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
179856108rs3015063AGrs3015063200389471.98E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
179856314rs3015065AGrs3015065200389471.96E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
179858023rs3000157TArs3000157200389474.91E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
179861842rs12030324GArs12030324200389472.10E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
179864610rs3000162CTrs3000162200389472.26E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
179870833rs3000165GArs3000165200389472.81E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
179873161rs3000166CTrs3000166200389472.92E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
179886246rs12046087CArs12046087200389473.34E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
179892025rs12039488GArs12039488200389473.45E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
179896125rs12041009TCrs12041009200389473.49E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
182436281rs1327022GArs1327022224728768.58E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
184296540rs970457CTrs970457208002215.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
184820409rs315535CTrs315535200389476.62E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
184856633rs12752696CTrs12752696220471848.23E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
184859152rs10082174CGrs10082174220471846.92E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
185704435rs7515154CTrs7515154240474461.99E-05NA1.3NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
186505755rs12143304AGrs12143304205161564.78E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
187184393rs3766008CTrs3766008208002216.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
187188921rs263462GArs263462208002216.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
187201299rs263482TCrs263482208002216.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
187203757rs263480CGrs263480208002214.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
187212934rs376906GArs376906208002214.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
187223804rs263491TGrs263491208002214.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
187227431rs263489ATrs263489208002214.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
187234742rs263485AGrs263485208002215.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
187577135rs12120670TArs12120670208002213.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
188055578rs9433138GArs9433138208002216.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
190866978rs10218464ATrs10218464203603159.47E-07NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
190869227rs6701608ACrs6701608203603154.66E-07NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
190875888rs2136093TCrs2136093203603154.00E-07whole sample8.3NA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
190879608rs1472887TCrs1472887203603155.85E-07NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
190894538rs7522605GCrs7522605203603157.72E-07NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
190915627rs1027854AGrs1027854203603157.55E-07NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
190916072rs1337576AGrs1337576203603152.35E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
190920022rs506368GArs506368203603157.49E-07NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
190925982rs2136094CArs2136094203603155.86E-07NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
195240361rs2391423CTrs2391423200389474.62E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
197463150rs182358CTrs182358210423178.90E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
197832736rs12403997GArs12403997229077300.0002237NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
197854245rs4950031TGrs4950031229077300.0001162NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
197855144rs7538155TCrs7538155229077300.0001162NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
197856731rs7530072CTrs7530072229077300.0001162NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
198569656rs1507061GArs1507061216212691.61E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
198627901rs12734505AGrs12734505216212692.34E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1100798137rs7534479GArs7534479208002216.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1101187219rs3176860AGrs3176860208002216.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1101360215rs3737580CTrs3737580208002211.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1101462232rs12023712GArs12023712208002211.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1101463138rs12119832GArs12119832208002211.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1101476712rs11166536GCrs11166536208002211.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1101984932rs263918CTrs263918224728768.97E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1103457229rs12756627AGrs12756627208002217.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1103458395rs12724152CArs12724152208002217.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1103463624rs12723167GArs12723167208002217.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1103465596rs12733933GArs12733933208002217.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1104798853rs12407649CArs12407649213168605.10E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1104887259rs10785866GArs10785866213168607.53E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
1105081773rs11184197GArs11184197213168603.22E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
1105086051rs6695172TCrs6695172213168602.61E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1105089396rs2121956AGrs2121956213168602.03E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1105113849rs7552405CTrs7552405213168601.21E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATNA
1105140299rs12568560GArs12568560213168606.81E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
1108286971rs6583045AGrs6583045217507022.57E-05Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGVAV3
1108888654rs12404827AGrs12404827210423174.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1110031188rs12049330TGrs12049330201250886.00E-06NA1.44NA1,020 European cases; 1,636 European controlsEuropean(2656)ALL(2656)EUR(2656)ALL(2656)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs12049330-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1110119732rs6537837CTrs6537837201250881.00E-06NA1.43NA1,020 European cases; 1,636 European controlsEuropean(2656)ALL(2656)EUR(2656)ALL(2656)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs6537837-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1112450636rs2995807TCrs2995807232901966.15E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1114716196rs2629817CTrs2629817240474463.77E-05NA1.52NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
1115873047rs10776799GTrs10776799224728762.52E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1115877624rs17033706GArs17033706224728768.27E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1116239266rs17034230CTrs17034230208002215.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1116240212rs3811006CTrs3811006208002215.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1147364001rs903786GA,C,Trs903786210423171.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1147364076rs903785ACrs903785210423171.30E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1147364099rs903784CA,G,Trs903784210423171.40E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1147365020rs2352834GA,C,Trs2352834210423174.70E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1150402419rs12738490TCrs12738490224728761.99E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1152880672rs1854779TCrs1854779213168605.56E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
1158743995rs11265070AGrs11265070208002216.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1159920719rs16831153GArs16831153197363533.40E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1162000398rs7551221TCrs7551221210423175.80E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1162091284rs12140791CTrs12140791231494480.0000638NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1162862846rs12124253ACrs12124253208002217.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1162864403rs4657236ATrs4657236208002211.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1162864476rs10917632CTrs10917632208002212.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1162865197rs10917633TCrs10917633208002213.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1163906277rs1961041TCrs1961041220471841.27E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1163912523rs4657319GC,Trs4657319220471841.96E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1163917950rs12033122CArs12033122220471849.44E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1163919788rs12027802GArs12027802220471843.38E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1165377552rs2134095GArs2134095224728765.10E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1165378064rs3767339ACrs3767339224728766.42E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1165380623rs10489744GArs10489744224728766.86E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1166235714rs2599513TCrs2599513229077300.0002028NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1166264243rs2568106CTrs2568106229077300.0001063NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1166264243rs2568106CTrs2568106229077300.0001122NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1166607463rs491814CTrs491814229077300.0001761NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1166610608rs3125821GArs3125821229077300.0001761NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1166628260rs565064CTrs565064229077300.0001761NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1166631859rs579089TCrs579089229077300.0001761NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1166856059rs4656517GArs4656517216212695.12E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1168689940rs545833CTrs545833229077300.0002193NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1172264401rs2757490CTrs2757490208002217.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1175157838rs3766682AGrs3766682197363536.10E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1178484065rs12754916AGrs12754916220471841.83E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1181154177rs946645AGrs946645220471848.46E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1182280599rs12024291CTrs12024291210423171.20E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1182283571rs16858833GCrs16858833210423178.00E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1182291435rs6703548TGrs6703548210423177.40E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1182291545rs10797766GArs10797766210423174.20E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1183834061rs9425322GArs9425322203603152.76E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1183834276rs9425323CTrs9425323203603151.53E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1183837032rs4651156AGrs4651156203603153.00E-06nortriptyline12.6NA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1183839005rs9425326TCrs9425326203603154.22E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1183841103rs9425616GCrs9425616203603152.21E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1183841784rs9425617TArs9425617203603152.14E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1183841796rs10797917TGrs10797917203603154.34E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1184764824rs35704242CTrs35704242216212696.32E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACFAM129A
1188117353rs12129062CTrs12129062191071151.04E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1188178381rs11810998TGrs11810998191071152.81E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1189788319rs10800667AGrs10800667208002215.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1191546574rs12751302CTrs12751302217507021.61E-06Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCNA
1193889533rs10921464CTrs10921464205161566.68E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
1193921548rs606149CTrs606149205161563.00E-06NA1.25NA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyG
1193921548rs606149CTrs606149229153520.00000219NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset>25HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNA
1195832253rs16838980TGrs16838980240474461.67E-05(Quantitative)0.72[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs16838980-G
1199357586rs693911GCrs693911200389476.26E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1199359440rs595113CArs595113200389476.02E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1199360977rs493474CTrs493474200389474.13E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1199362153rs638079CTrs638079200389475.86E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1199362216rs571609CTrs571609200389475.84E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1199364111rs4562659GTrs4562659200389475.83E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1199374488rs661480CArs661480200389477.43E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1199377000rs585476ACrs585476200389477.64E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1199378212rs628061CTrs628061200389475.94E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1199386880rs528227TCrs528227200389477.65E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1199395968rs516182GArs516182200389478.07E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1199396278rs826937AGrs826937200389478.08E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1199407512rs580169TCrs580169200389478.06E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1199422097rs729439CGrs729439200389477.83E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1199429509rs1337730GArs1337730200389472.63E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1199431121rs7535498TCrs7535498200389479.32E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1199431778rs4915175GCrs4915175200389479.39E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1200024300rs2821379GArs2821379220471845.33E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1200025886rs2737645TCrs2737645220471842.52E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1200033769rs2821388AGrs2821388220471847.63E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1200034969rs2816916AGrs2816916220471847.97E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA,G
1200293042rs2808473CTrs2808473208002212.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1200437506rs12058730AGrs12058730240474462.69E-05(Quantitative)0.71[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs12058730-G
1200721265rs17750695AGrs17750695240474461.50E-05(Quantitative)0.82[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs17750695-G
1201041480rs2886329AGrs2886329197363531.50E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1205546615rs12759507CTrs12759507208002219.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1210829477rs4951508TCrs4951508229077300.0002249NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1210858222rs2357921CTrs2357921220471848.04E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1210858403rs4628571CTrs4628571220471845.87E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1210860558rs12141923CTrs12141923220471846.24E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1212379741rs11119881ACrs11119881191071151.98E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1213586276rs320462GCrs320462198460675.99E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
1214026324rs2236580CTrs2236580216212698.69E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGPROX1-AS1
1215120353rs1377185CTrs1377185216212694.56E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1215120353rs1377185CTrs1377185pha0028503.16E-05phs0000201.33NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNANANA
1215120596rs556648GArs556648216212699.05E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1215120596rs556648GArs556648pha0028503.84E-05phs0000201.28NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
1215850892rs11120597GArs11120597208002218.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1216074957rs1325523CArs1325523198460678.81E-06NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGUSH2A
1216649667rs4338426CTrs4338426197363532.20E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1217082385rs1436879CTrs1436879208002219.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1217200883rs2377360GArs2377360233776409.00E-06remission - SSRI treated - 12 weeks1.6[1.39-1.81] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs2377360-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1217270667rs830307ACrs830307220471843.52E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1217281640rs11117772TCrs11117772208002214.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1217282499rs987445GTrs987445208002214.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1220119384rs11118465ACrs11118465197363532.20E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1220275378rs2789788GArs2789788220471847.80E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1221277508rs12125058CTrs12125058200389474.65E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1221287861rs1442459CArs1442459200389475.56E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1222504752rs1155471AGrs1155471240474464.03E-05(Quantitative)0.38[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs1155471-G
1224246746rs6663154TGrs6663154224728769.60E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1224538940rs11579964CTrs11579964210423174.00E-06NA1.19NA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs11579964-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1224538940rs11579964CTrs11579964224728761.01E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1224538940rs11579964CTrs11579964232901964.40E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1224820292rs6695864GTrs6695864200389477.54E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1227047256rs1150896TCrs1150896220471849.88E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1227667790rs12410462GArs12410462233776404.00E-07% improvement - 12 weeks1.26[1.16-1.36] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs12410462-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1229360505rs2988738TCrs2988738230914230.00000448NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Norepinephrine reuptake inhibitors (NRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1234461183rs12133361CTrs12133361208002215.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1234601586rs270504GArs270504210423175.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1235272357rs7411516CTrs7411516229077300.0001228NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1236444658rs11587363TCrs11587363224728762.53E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1236545893rs6673040TGrs6673040224728767.89E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1236546142rs4659657GArs4659657224728766.09E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1236547422rs1025977TGrs1025977224728768.00E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1236552530rs4659660AGrs4659660224728766.42E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1236555310rs4659664ATrs4659664224728762.39E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1236557412rs10802533TGrs10802533224728761.02E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1236557771rs966365GArs966365224728767.80E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1236557928rs966364GArs966364224728769.55E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1237561361rs10925405CTrs10925405197363531.20E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1237796092rs476078TCrs476078200389475.59E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1237797757rs10925480AGrs10925480200389479.18E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1237797973rs7526807CTrs7526807200389478.42E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1237797997rs7538471AGrs7538471200389473.21E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1238300214rs10925573TGrs10925573198460672.09E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tTNA
1238442713rs12094201AGrs12094201224728766.22E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1238923765rs2841409GCrs2841409224728769.49E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1240885642rs6678643GArs6678643208002217.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1241452500rs12090898CTrs12090898191071157.31E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACRGS7
1242235655rs1589263AGrs1589263216212691.60E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
1243114662rs10803102GArs10803102229077300.0001579NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1247547334rs7555997CArs7555997232901963.46E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
21099654rs13389243CTrs13389243208002217.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
21497803rs1126797CA,G,Trs1126797205161562.48E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
21525558rs4927594CTrs4927594205161563.32E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyT
22533488rs11676482CGrs11676482198460671.44E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
25559013rs1524483TGrs1524483224728769.59E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
25818277rs6740618TGrs6740618220471846.42E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
25818713rs6740458ATrs6740458220471846.58E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
25818895rs6735027CArs6735027220471843.52E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
25819288rs12621309GArs12621309220471847.04E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
25819517rs10929756CTrs10929756220471846.38E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
25821748rs4547512GTrs4547512220471846.61E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
25824158rs6734206CGrs6734206220471847.51E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
25825923rs10206204GTrs10206204220471846.56E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
26729633rs12998104CTrs12998104208002215.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26733673rs13401852GArs13401852208002214.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26734181rs13393305AGrs13393305208002214.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26735155rs13383761CTrs13383761208002215.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26739006rs6732257CArs6732257208002213.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26743067rs1461312ATrs1461312208002213.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26747503rs6717016GArs6717016208002213.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26754148rs13387837GArs13387837208002214.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26758874rs10204937AGrs10204937208002215.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26761631rs7575004CTrs7575004208002215.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26769318rs7584788CTrs7584788208002214.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26772729rs12692323TArs12692323208002214.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26774326rs376286195CCTTArs6714052208002211.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26774326rs6714052CA,Trs6714052208002211.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26774326rs76628858CCTTArs6714052208002211.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26777264rs13421943CTrs13421943208002213.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26781149rs7561212GArs7561212208002211.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
26922783rs11683777CTrs11683777232901965.77E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
27490156rs2352714AGrs2352714pha0028508.20E-05phs0000201.32NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAG,ANANANA
29832407rs6741886GArs6741886216212697.77E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
29890804rs4668644AGrs4668644191071156.77E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
29893454rs13412895TCrs13412895191071156.24E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
29922283rs4669458TCrs4669458240474464.11E-05NA1.35NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
210422939rs7566637CTrs7566637200389473.20E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
212296582rs731395GArs731395229077300.0000158NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
212304753rs3954862TCrs3954862229077300.000013NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
212304753rs3954862TCrs3954862229077300.0001575NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
212305222rs3906767CTrs3906767229077300.000013NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
212305222rs3906767CTrs3906767229077300.0001575NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
212323369rs10803744GArs10803744229077300.0000992NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
212399050rs2380426CTrs2380426229077300.0002247NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC,T
214334195rs7571070CTrs7571070213168603.36E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATNA
214398052rs16861531GCrs16861531220414587.00E-07Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers16861531-G
219705084rs4666491GArs4666491208002219.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
220256192rs12471796GArs12471796190651441.40E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
220256192rs12471796GArs12471796216212692.77E-06NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
220256192rs12471796GArs12471796pha0028501.51E-05phs0000201.26NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNANANA
220256838rs12472043GArs12472043231494480.00000519NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
220261685rs7565124GArs7565124190651441.10E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
220261685rs7565124GArs7565124216212692.00E-06NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
220261685rs7565124GArs7565124pha0028501.38E-05phs0000201.26NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNANANA
220270027rs2126551AGrs2126551231494480.0000217NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
220678496rs2084919TCrs2084919232901966.23E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
221297447rs565202AGrs565202197363531.70E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
223360855rs1562751TArs1562751208002215.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223361001rs1562752CArs1562752208002215.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223364711rs1449965GArs1449965208002218.24E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223369473rs10194644CTrs10194644208002215.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223370317rs10197888CTrs10197888208002215.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223402150rs6716929CTrs6716929208002218.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223403834rs6721782CGrs6721782208002217.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223410734rs1375864GCrs1375864208002219.27E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223414651rs1449984AGrs1449984208002217.00E-06NA0.15[NA] unit decrease3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs1449984-AMeta-AnalysisResearch Support, N.I.H., Intramural
223414651rs1449984AGrs1449984232901966.60E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
223442158rs1449968TGrs1449968208002212.91E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223476896rs9789344AGrs9789344208002218.00E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223494356rs2577734CArs2577734208002219.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223520587rs10187596GArs10187596208002213.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223522173rs1469974GArs1469974208002215.06E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223522489rs17675487AGrs17675487208002215.19E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223524378rs9789743CGrs9789743208002215.48E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223524674rs9789522GCrs9789522208002215.52E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
223724991rs1653763TGrs1653763191071151.27E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACKLHL29
223729232rs1653765AGrs1653765191071156.93E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAKLHL29
225077991rs6760328TCrs6760328210423173.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
225082414rs1541984GArs1541984210423173.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
225089166rs7597157CTrs7597157210423176.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
225101092rs2033655GArs2033655210423171.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
225106265rs12986610CTrs12986610210423175.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
225130092rs7565468CTrs7565468210423177.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
225135620rs2384061GArs2384061210423176.30E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
228520083rs10189899AGrs10189899pha0028505.82E-05phs0000201.22NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGBREintronNM_199193
229280761rs882632CTrs882632201250882.00E-06NA1.34NA1,020 European cases; 1,636 European controlsEuropean(2656)ALL(2656)EUR(2656)ALL(2656)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs882632-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
229383374rs2305450GArs2305450217507023.69E-05Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tACLIP4
229392680rs12620500CTrs12620500208002219.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
229685596rs3923028CTrs3923028190651442.00E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
229685596rs3923028CTrs3923028216212693.11E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAALK
229685596rs3923028CTrs3923028pha0028503.80E-05phs0000201.34NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAALKintronNM_004304
229795988rs13014477TGrs13014477229077300.0000264NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
229795988rs13014477TGrs13014477229077300.000075NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
231249105rs4952029CGrs4952029220471844.49E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
231556986rs6543626CTrs6543626200389476.62E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
231891571rs13027103GArs13027103200389473.98E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
233365244rs6737948GArs6737948229077300.00014NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
233604048rs6719824ACrs6719824213168603.69E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACLTBP1
234381971rs17470247AGrs17470247229077300.0001914NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
237629222rs10173794AGrs10173794216212697.50E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
237646632rs13002028ACrs13002028210423174.40E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
238018661rs1579491GArs1579491224728761.48E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
242122150rs2374380GC,Trs2374380200389478.27E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
242129211rs4952533GCrs4952533200389478.93E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
243012336rs2374443CTrs2374443240474464.62E-05NA1.44NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
244014301rs3765000AGrs3765000213168608.58E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATDYNC2LI1
244029821rs4952679CTrs4952679213168609.82E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATDYNC2LI1
245864710rs2344662ACrs2344662240474462.27E-05(Quantitative)0.41[NA] unit decrease1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs2344662-C
245992857rs4953249GArs4953249217507027.30E-06Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tAPRKCE
247095205rs12990097GCrs12990097224728761.20E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
247182032rs17035931ACrs17035931205161562.21E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
247184447rs6726941CTrs6726941210423177.70E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
247227768rs17036033GArs17036033210423173.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
250840322rs12476492AGrs12476492229153520.000005NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<15HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNRXN1
251266982rs2352545CTrs2352545232901969.33E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
251270610rs2111380ATrs2111380232901968.65E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
251279135rs4971723TCrs4971723232901967.79E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
251282609rs6545190GTrs6545190232901969.25E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
251292332rs10180695TCrs10180695232901967.78E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
256454266rs17268688CTrs17268688210423177.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
256502903rs214042ACrs214042224728761.26E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
261540612rs11680679TCrs11680679224728765.54E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
264124722rs11558741CArs11558741220471842.40E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
264180957rs6736556CTrs6736556220471842.40E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
264194247rs6757168CTrs6757168220471843.40E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
264196920rs7560265CTrs7560265220471847.06E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
264207445rs6546043CArs6546043220471845.17E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
264517384rs2433383CTrs2433383208002216.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
265230739rs3770705TCrs3770705230914230.00000437NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
265747442rs702938AGrs702938224728766.02E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
265758355rs3845816AGrs3845816224728762.94E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
265758450rs702891CGrs702891224728763.55E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
265758525rs3845817TCrs3845817224728761.98E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
265759671rs3911862AGrs3911862224728763.09E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
265767247rs702909GTrs702909224728761.89E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
265772291rs702919CTrs702919224728762.57E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
265772956rs13003991CGrs13003991224728762.09E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
265774687rs11678288TArs11678288224728762.03E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
267204642rs12471464TCrs12471464205161561.74E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyT
267279175rs990255ACrs990255208002214.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
267290698rs17032961AGrs17032961208002214.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
267305081rs17033002GTrs17033002208002214.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
267307202rs3821130TCrs3821130208002214.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
267311169rs752939GTrs752939208002214.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
267311224rs752938CGrs752938208002214.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
267313661rs6741648GArs6741648208002214.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
267332744rs17033084GCrs17033084208002213.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
267539226rs7572809GArs7572809208002219.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
267916875rs11675008AGrs11675008200389473.56E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
267916928rs11692071TGrs11692071200389472.66E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
267918196rs4671836AGrs4671836200389472.58E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
267920930rs4671839TCrs4671839200389478.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
267921037rs10169649TArs10169649200389475.69E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
267921216rs4671840AGrs4671840200389475.17E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
267921216rs4671840AGrs4671840231494480.000033NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
267921411rs4671841ACrs4671841200389471.35E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
267932298rs1367467AGrs1367467200389471.30E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
267932740rs989720TCrs989720200389471.48E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
267933079rs1430770GArs1430770200389471.25E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
267933177rs1430771CGrs1430771200389474.64E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
267939457rs13403823CTrs13403823200389475.58E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
267942480rs724568CArs724568200389475.00E-06NA1.17NA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionrs724568-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
267945371rs4671842TCrs4671842200389477.87E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
267946891rs10865363CTrs10865363200389476.96E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
267950632rs737358GArs737358200389476.61E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
267952811rs4671197TCrs4671197200389477.97E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
267973887rs13432159TGrs13432159220414589.00E-08Sertraline, General SENANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers13432159-G
267976788rs6724422CTrs6724422220414584.00E-07Sertraline, General SENANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers6724422-T
269437291rs4464317CTrs4464317213168606.17E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACANTXR1
269489816rs6546493AGrs6546493208002215.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
274649934rs3732293ACrs3732293210423171.50E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
278500655rs1405274CTrs1405274210423174.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
278501560rs1818965AGrs1818965210423176.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
278521092rs17015127AGrs17015127210423177.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
278523914rs6743486CTrs6743486210423178.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
279069569rs4853414CTrs4853414224728761.61E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
280885470rs13382374TCrs13382374208002217.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
280898579rs7574764TCrs7574764208002217.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
280900868rs13404209CGrs13404209208002217.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
282957950rs12328118AGrs12328118229077300.0000493NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
282965627rs6547441GArs6547441229077300.0001456NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
282978565rs1393509GArs1393509229077300.0001456NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
282981654rs11692714TCrs11692714229077300.000062NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
282989156rs17022382TCrs17022382229077300.0001456NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
282991635rs17022383GArs17022383229077300.000062NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
283011373rs7571839TCrs7571839229077300.0001456NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
284800898rs13002679TCrs13002679229077300.0002415NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
286485315rs17510512TCrs17510512210423174.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
286632902rs6713586TA,Crs6713586229077300.0001088NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
297405440rs2271893GArs2271893224728762.08E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
297410949rs6746896AGrs6746896224728762.26E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
299573471rs6542847AGrs6542847224728761.38E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
299873658rs17022433TArs17022433224728769.15E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
299886301rs1955393GArs1955393224728761.20E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
299888457rs901596CTrs901596224728761.80E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
299938942rs12464785AGrs12464785224728766.18E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
299999097rs2290255CArs2290255224728764.17E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100021184rs2290261AGrs2290261224728764.63E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100022270rs1053544GArs1053544224728763.95E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100022772rs717454TCrs717454224728764.10E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100051522rs3792146CTrs3792146224728766.11E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100055506rs3087386AGrs3087386224728766.02E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100061748rs3792137CArs3792137224728764.53E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100064072rs11899745AGrs11899745224728764.41E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100067554rs7594838CTrs7594838224728765.51E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100067578rs7567674GArs7567674224728765.69E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100068069rs4851206TCrs4851206224728764.84E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100069385rs10172752TGrs10172752224728765.93E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100077327rs7585019GCrs7585019224728764.78E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100077966rs769105GArs769105224728764.21E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100094799rs1011633CTrs1011633224728763.71E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100105312rs6714244AGrs6714244224728766.11E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2100109001rs6715321CTrs6715321224728764.66E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2102178726rs11687533CTrs11687533240474462.54E-05NA1.39NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs11687533-T
2102671681rs4851536TGrs4851536224728769.13E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2103572929rs2310351TGrs2310351210423174.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2104827991rs12712185ATrs12712185200389474.82E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2105754747rs10191425ACrs10191425208002212.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2105771650rs4605389TCrs4605389208002213.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2105778288rs7583476ATrs7583476208002213.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2105778430rs7569958CTrs7569958208002213.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2105779411rs13411784ACrs13411784208002213.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2105791914rs13388299TCrs13388299208002215.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2106605186rs1109164GArs1109164208002219.11E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2109782233rs7561185TCrs7561185210423173.80E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2109788623rs4676070CTrs4676070210423173.40E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2109798726rs4676258CTrs4676258210423171.70E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2109807143rs11893469CTrs11893469210423174.70E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2109807885rs1430306GArs1430306210423173.80E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2112649472rs13016143CTrs13016143208002218.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2113083283rs4352239ACrs4352239200389474.85E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2113098812rs4299347TCrs4299347200389475.96E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2119894965rs7557802CTrs7557802208002213.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2120008556rs734846TGrs734846208002216.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2120008735rs734845ACrs734845208002216.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2121001117rs4848580CTrs4848580197363534.00E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
2121553197rs10169929ATrs10169929220471844.95E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
2122511856rs7562021TCrs7562021220471842.87E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
2122537773rs12618503CTrs12618503220471845.09E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
2122578042rs7577075AGrs7577075220471846.92E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
2122594780rs6761482GArs6761482220471847.74E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
2122599806rs10460462GTrs10460462220471847.86E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
2122599911rs6724570GArs6724570220471842.31E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
2122600116rs6753114AGrs6753114220471842.32E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
2122601302rs10460453TCrs10460453220471842.32E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
2122610306rs7595430CGrs7595430220471846.67E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
2122943468rs4848174CTrs4848174229077300.0001934NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2122951824rs2163656CTrs2163656220471847.71E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
2123397312rs7582802GArs7582802208002218.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2123401043rs7594595CArs7594595208002218.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2123401189rs7608903TCrs7608903208002218.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2123403621rs1595757TCrs1595757208002219.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2123407250rs10166255TCrs10166255208002219.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2123431555rs10201125CTrs10201125208002218.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2123432820rs6541846AGrs6541846208002218.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2123438579rs2418650CArs2418650208002219.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2123440796rs10166571CTrs10166571208002219.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2124944244rs7558429CTrs7558429224728762.45E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2124946945rs7569367CTrs7569367224728762.19E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2125383348rs1454133GTrs1454133208002219.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2125385662rs4848252AGrs4848252208002217.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2125391317rs1587788TCrs1587788208002219.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2125391574rs2219107TGrs2219107208002218.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2125391858rs7599787AGrs7599787208002219.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2125392103rs12995183TCrs12995183208002218.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2125394477rs11675141TGrs11675141208002217.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2125394477rs70996085TTTCTCTTTTTCTCCTCTCCTCTGrs11675141208002217.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2127413135rs3811541AGrs3811541229077300.0000314NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2127413135rs3811541AGrs3811541229077300.0001811NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2127621402rs4413107TCrs4413107208002217.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2127924191rs7587554CTrs7587554232901966.85E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2130643612rs4662667GArs4662667229077300.0001493NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2134695073rs13389356TArs13389356208002215.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2135781035rs16831256CTrs16831256208002218.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2135839805rs6728452CTrs6728452208002217.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2136264631rs16831751AGrs16831751208002218.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2136613461rs4988218TCrs4988218208002218.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2137522044rs2001872AGrs2001872229077300.000191NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2139914818rs10196730CArs10196730224728761.91E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2139938408rs1437296GArs1437296224728762.64E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2139959808rs10181724CTrs10181724224728761.59E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2139961825rs1437305GArs1437305224728761.97E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2139976061rs934707GTrs934707224728763.17E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2141813216rs16845233CArs16845233208002218.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141826995rs16845274TArs16845274208002219.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2142989440rs4473327GArs4473327208002214.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2142994927rs4297822TGrs4297822208002214.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2150987418rs16827839GArs16827839224728769.91E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2152844074rs17270394ACrs17270394208002212.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2154330785rs3910522CArs3910522224728762.97E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2154372766rs1221754TCrs1221754200389476.83E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2154375056rs1370674ACrs1370674200389471.51E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2154816802rs13030825TCrs13030825229077300.0001815NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2154837081rs6761233AGrs6761233229077300.0001484NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2159411420rs3771603GArs3771603208002213.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2161203395rs7425274TCrs7425274208002218.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2161863052rs10208511AGrs10208511208002212.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2161901948rs4664397GArs4664397213168603.32E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
2164675913rs16848941TCrs16848941216212698.04E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
2164720199rs12994524CTrs12994524216212694.78E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
2164725276rs10930111ACrs10930111216212698.24E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
2164768717rs10184708TCrs10184708216212698.66E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
2164885707rs2176241TGrs2176241208002217.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2164894561rs12692709TCrs12692709216212695.75E-06NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
2164926908rs393093GArs393093224728763.30E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2165356343rs570657AGrs570657200389473.52E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2165358672rs4667463AGrs4667463200389473.52E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2165366592rs582447ACrs582447200389472.74E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2165424837rs17437781AGrs17437781200389475.04E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2165427825rs1521527GCrs1521527200389473.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2165429235rs11677541GA,C,Trs11677541200389476.15E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2165437544rs1521522CGrs1521522200389477.36E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2166534206rs1820325AGrs1820325229077300.0001568NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2168574523rs2044682CArs2044682224728762.34E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2169338808rs16855373GCrs16855373224728761.89E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2169509692rs6707065CA,Grs6707065208002213.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2172057864rs218311TCrs218311213168605.72E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATTLK1
2174238868rs6747034AGrs6747034208002215.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2175463793rs13427312TGrs13427312220471842.62E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
2175466160rs10221651AGrs10221651220471841.29E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
2175466441rs6756690GArs6756690220471841.48E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
2175471607rs4595937GTrs4595937220471841.08E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
2175475851rs6745914AGrs6745914220471841.68E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
2177028551rs7606110TCrs7606110208002215.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2177032267rs2301301TCrs2301301208002214.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2177035395rs13017511AGrs13017511208002216.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2177037970rs9141TCrs9141208002217.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2177043971rs1374325GArs1374325208002219.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2177929191rs12105278CGrs12105278208002215.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2180399670rs16866767GArs16866767208002217.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2180400813rs6709838CTrs6709838208002216.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2180403128rs11884072TCrs11884072208002215.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2181698136rs6758984AGrs6758984224728763.81E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2181755429rs4666644GCrs4666644224728761.23E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2181757693rs13031974AGrs13031974224728761.73E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2181779679rs4263076CTrs4263076224728762.76E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2184371403rs9288091GArs9288091229077300.0000798NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2184458832rs2368423GTrs2368423200389476.73E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2184479350rs13384559AGrs13384559200389476.24E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2184483143rs6737900CTrs6737900200389476.16E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2184484253rs6742026CTrs6742026200389476.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2185533580rs7597593TCrs7597593224728762.04E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2185778428rs1344706ACrs1344706224728762.76E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2185783141rs1583048TCrs1583048224728763.12E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2187126560rs13421948TCrs13421948210423177.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2187149967rs4522568ACrs4522568210423177.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2187150058rs4530331GArs4530331210423174.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2187156914rs6744814GArs6744814210423175.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2187264986rs12467212AGrs12467212210423176.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2188957640rs1439912TCrs1439912229077300.0002087NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2189799682rs4667253TCrs4667253208002219.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2190376388rs11692009GArs11692009208002214.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2190376873rs10206036GArs10206036208002215.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2192704044rs4853645ATrs4853645231494480.0000417NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2192712723rs7583029GArs7583029210423178.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2193742173rs10174573CTrs10174573233776402.00E-06partial response - 2 weeks1.56[1.39-1.74] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs10174573-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2194652248rs13018978CArs13018978208002215.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194660331rs4473398TGrs4473398208002215.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194663490rs1358626TCrs1358626208002215.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194679200rs10497745CArs10497745208002214.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194706556rs16835330AGrs16835330208002214.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194707606rs12991562CTrs12991562208002214.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194715328rs10209427TCrs10209427208002214.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194716457rs1358625TCrs1358625208002214.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194722073rs10931625CTrs10931625208002214.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194727038rs6740862CTrs6740862208002214.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194730749rs6434632CTrs6434632208002214.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194733623rs1534690CTrs1534690208002214.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194735679rs4850493ATrs4850493208002214.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194736257rs10184447CTrs10184447208002214.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194739062rs4850495AGrs4850495208002212.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194739622rs4850496AGrs4850496208002211.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194739945rs1529108AGrs1529108208002212.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194744710rs13029940TCrs13029940208002213.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194746880rs4402780AGrs4402780208002213.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194747064rs10179597AGrs10179597208002212.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194749514rs7561862CTrs7561862208002217.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194785328rs4468836CArs4468836208002219.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194805093rs6750903GArs6750903208002218.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2194810279rs11892785TCrs11892785208002216.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2196715003rs10497770GArs10497770229077300.0001883NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2196849453rs17363011CTrs17363011229077300.0000945NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2196894770rs6414150AGrs6414150229077300.0000498NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2196912067rs4850381AGrs4850381229077300.0000842NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2199775467rs6434989CTrs6434989216212695.52E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
2200137608rs2881208TCrs2881208216212697.77E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATSATB2
2201648639rs13430864TGrs13430864227605535.00E-07EA + AA - DizzinessNANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs13430864-G
2201652453rs13423450TCrs13423450227605533.33E-05NANANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression casesNOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNA
2201968940rs12621441GArs12621441190651442.40E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2201968940rs12621441GArs12621441216212693.22E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
2201968940rs12621441GArs12621441pha0028503.43E-05phs0000201.31NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNANANA
2202855194rs4675242AGrs4675242197363531.10E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
2205974111rs6715145TCrs6715145229077300.000088NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2205974111rs6715145TCrs6715145229077300.0002364NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2206131317rs2336413AGrs2336413229077300.0000665NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2206184135rs7567356CGrs7567356208002215.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2206260544rs6711300AGrs6711300208002218.47E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2208026913rs10932180TCrs10932180216212695.55E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATKLF7
2208046998rs2111593CTrs2111593216212695.18E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
2208178532rs9288382CTrs9288382208002217.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2209028191rs796280CTrs796280210423175.50E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2209029192rs2123291ACrs2123291210423176.20E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2217199624rs955816AGrs955816240474462.34E-05(Quantitative)0.4[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs955816-G
2217980433rs12466929GArs12466929229077300.0001454NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2218869388rs934036AGrs934036200389476.23E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2221000018rs12614221GTrs12614221224728763.42E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2221596539rs16861701GArs16861701208002216.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2223353778rs1436786TCrs1436786191071158.10E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGSGPP2
2223852436rs13033186CTrs13033186208002216.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2223854254rs11687274GTrs11687274208002216.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2223857554rs935028AGrs935028208002214.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2224300897rs16864788GArs16864788208002215.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2224602647rs625588TCrs625588210423177.90E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2225478729rs10498164CTrs10498164208002218.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2227226621rs2894592TGrs2894592220471842.07E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
2229087980rs7569857CTrs7569857208002218.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229088071rs7596305AGrs7596305208002217.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229088182rs7570056CArs7570056208002217.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229088564rs6734910TCrs6734910208002217.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229088999rs4973623ACrs4973623208002217.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229089087rs4973077TCrs4973077208002217.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229089667rs7577217GArs7577217208002217.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229090591rs6756442AGrs6756442208002217.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229090681rs11687136CTrs11687136208002217.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229091495rs6738921ATrs6738921208002217.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229091508rs6710405CTrs6710405208002217.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229092221rs7565432GArs7565432208002217.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229093362rs12467514AGrs12467514208002217.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229099320rs7591756GArs7591756208002217.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229100109rs13394977CArs13394977208002217.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229100197rs13395080CTrs13395080208002217.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229100407rs9989832TCrs9989832208002217.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229103185rs6752284TCrs6752284208002217.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229104720rs7593752GArs7593752208002219.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229104755rs7607608TGrs7607608208002219.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229106949rs10804339TCrs10804339208002219.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229107336rs6753687GTrs6753687208002218.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229107495rs6711657TCrs6711657208002218.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229115093rs1316628TCrs1316628208002218.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2230141849rs10498237AGrs10498237240474463.39E-05(Quantitative)0.48[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs10498237-G
2232564881rs13398149ACrs13398149224728766.50E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2232572381rs6737601AGrs6737601224728761.35E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2232579795rs6755895TCrs6755895224728763.17E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2232584807rs11695646AGrs11695646224728762.02E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2232726300rs1866599CTrs1866599224728766.07E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2234718524rs11674078TCrs11674078pha0028505.49E-05phs0000201.27NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATHEATR7B1intronXM_291007
2235505424rs13013073GCrs13013073232901966.73E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2235626160rs4663163AGrs4663163205161562.76E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyG
2235693788rs13016879GArs13016879208002213.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2235699767rs894188CTrs894188208002211.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2235720850rs13022629AGrs13022629208002217.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2239890696rs4852066GArs4852066208002219.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2239891296rs4851977GArs4851977208002219.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2239891644rs6543542TCrs6543542208002219.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2239899327rs4852079AGrs4852079208002218.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2241684692rs7576602CTrs7576602208002217.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3172477rs6795349AGrs6795349220414582.00E-06Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers6795349-G
3336454rs17021268GCrs17021268220471847.99E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
31551708rs12487870GArs12487870pha0028503.85E-05phs0000201.35NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNANANA
31587860rs400048TCrs400048216212698.10E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
31597057rs11712183TCrs11712183pha0028506.06E-05phs0000201.26NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNANANA
33593290rs7650676CGrs7650676208002218.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
33600161rs1072848AGrs1072848208002217.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
33641794rs11711298GCrs11711298208002212.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
33650239rs9837561ACrs9837561208002212.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
33671849rs901859AGrs901859208002219.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
33672111rs11129700GTrs11129700208002214.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
34567628rs11708874TGrs11708874198460679.65E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tTITPR1
34682229rs4073665GArs4073665232901963.05E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
35427290rs6799552CTrs6799552229077300.0002223NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
36231998rs9839456CTrs9839456229077300.0001724NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
37529555rs9870680CTrs9870680200389471.00E-06NA1.19NA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionrs9870680-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
37529555rs9870680CTrs9870680231494480.0000837NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
37529849rs9815274ATrs9815274200389472.01E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
37529849rs9815274ATrs9815274224728766.43E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
37542268rs1375923CTrs1375923200389474.29E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
37555709rs1531940TArs1531940200389471.37E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
37558907rs6778646CTrs6778646200389471.18E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
37562685rs1106485CGrs1106485200389472.25E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
37578273rs7651961TCrs7651961200389472.25E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
37578563rs7652246TGrs7652246200389471.99E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
37578602rs6443114ATrs6443114200389471.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
37583314rs17664833CGrs17664833200389471.31E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
37583314rs17664833CGrs17664833216212698.12E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACGRM7
37583602rs779741CArs779741200389471.35E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
38030809rs9859247AGrs9859247213168608.45E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
38808515rs237899GArs237899220641622.00E-06NA1.69[1.36-2.10] 467 European ancestry cases; 407 European ancestry controlsEuropean(874)ALL(874)EUR(874)ALL(874)Depression and alcohol dependenceHPOID:0000716DepressionDOID:303DOID:1596substance-related disordermental depressionD003863DepressionNANADepressionDrug abuseNA
38905524rs11706378CTrs11706378208002213.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
38906866rs11715042GArs11715042208002211.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
38911347rs17734025TGrs17734025208002211.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
39288545rs2137216TCrs2137216210423179.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
311038807rs1710885TCrs1710885191071153.19E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATSLC6A1
312478817rs9833097GArs9833097216212695.57E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
312478817rs9833097GArs9833097pha0028506.72E-05phs0000201.36NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
314510761rs3773175TCrs3773175208002214.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314510861rs3773174TCrs3773174208002211.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314510886rs3773173TCrs3773173208002214.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314511699rs3773172GArs3773172208002214.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314512093rs3773171CTrs3773171208002214.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314512731rs9826660ACrs9826660208002214.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314513180rs9868733CTrs9868733208002214.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314513695rs2289128GArs2289128208002215.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314517115rs9834678TCrs9834678208002212.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314517282rs3773167GArs3773167208002211.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314517999rs9820113GTrs9820113208002216.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
314519102rs9845444TCrs9845444208002217.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
316285941rs842261GArs842261208002216.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
316432477rs690403CTrs690403191071152.22E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAARFTN1
316520435rs11128791TCrs11128791229077300.0002136NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
316885602rs6796955CTrs6796955224728764.14E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
316885685rs6797038CArs6797038224728768.33E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
318623123rs11707806CGrs11707806220471848.51E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
321380677rs2731943CTrs2731943205161562.63E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyT
322905895rs299070GArs299070231494480.0000108NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
325141279rs17516267GArs17516267208002213.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
325141612rs17575546TCrs17575546208002211.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
329949712rs7610139AGrs7610139208002215.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331314100rs7628394CTrs7628394208002213.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331316585rs6798661ACrs6798661208002213.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331321856rs6804612TCrs6804612208002213.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331322654rs9844475CTrs9844475208002213.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331323210rs9865155TCrs9865155208002213.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331324186rs9822344CGrs9822344208002213.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331324352rs9826665GArs9826665208002213.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331327951rs9310965CTrs9310965208002213.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331329185rs9811300AGrs9811300208002213.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331330024rs9873949TCrs9873949208002213.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331330858rs9859166CTrs9859166208002213.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331331119rs9879457TGrs9879457208002213.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331331273rs9825803ATrs9825803208002213.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331332995rs9870170GTrs9870170208002213.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331333290rs9865912TCrs9865912208002213.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331334622rs6764036TGrs6764036208002213.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
331857836rs13087711CTrs13087711210423173.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
333838124rs9843488TGrs9843488229077300.0001714NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
333865612rs7626555GArs7626555229077300.0001851NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
333877626rs3792594GArs3792594229077300.0002346NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
333900980rs10865850GArs10865850229077300.0002171NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
336856030rs9834970TCrs9834970224728765.41E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
336869439rs4789TCrs4789224728764.53E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
338736230rs12639182CTrs12639182200389476.65E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
340911348rs17051601GArs17051601208002219.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
345220085rs6767173TCrs6767173198460678.47E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
345731451rs2742417CTrs2742417220414585.00E-07Bupropion, sexNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers2742417-T
345934279rs12638201GArs12638201208002211.14E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
345937782rs3774642CGrs3774642208002213.37E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
345951678rs12493471TCrs12493471208002211.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
345954352rs9810934AGrs9810934208002214.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
345962752rs7652331TCrs7652331208002214.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
346005478rs1545985GArs1545985208002215.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
346025013rs4683159AGrs4683159208002219.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
346025518rs11130082TCrs11130082208002219.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
346026699rs13086858CArs13086858208002219.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
346029458rs1873000GCrs1873000208002219.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
346030003rs7628447CTrs7628447208002219.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
346143930rs1392296AGrs1392296208002215.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
346323859rs9839623AGrs9839623197363537.50E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
346692379rs9861101CTrs9861101208002215.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
346696797rs17079097TCrs17079097208002214.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
348570686rs11710798ACrs11710798208002217.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
351598254rs4687721GArs4687721208002219.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
351623216rs6809155AGrs6809155208002218.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
351650510rs6787312GArs6787312208002216.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
351656370rs9864693GCrs9864693208002216.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
351668409rs11917683GArs11917683208002216.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
351683248rs4494918GCrs4494918208002216.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
351695865rs4234644GCrs4234644208002216.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
352450043rs13094687AGrs13094687224728761.47E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352456973rs2272088AGrs2272088224728761.47E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352536514rs731831GArs731831224728761.89E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352584715rs2878628AGrs2878628224728766.90E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352584787rs2251219TCrs2251219224728761.91E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352585990rs1961958AGrs1961958224728766.98E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352593119rs17052256AGrs17052256224728765.80E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352593230rs3796353CTrs3796353224728766.56E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352596398rs6778844TCrs6778844224728766.98E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352597664rs2289249GArs2289249224728769.02E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352599789rs6786919AGrs6786919224728767.32E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352602274rs13063160TCrs13063160224728767.65E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352604861rs6786043AGrs6786043224728766.61E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352606292rs11714565CTrs11714565224728766.51E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352610415rs7652191TCrs7652191224728765.65E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352618018rs11720243TCrs11720243224728765.65E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352618319rs12487445ACrs12487445224728767.93E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352621839rs3852066CTrs3852066224728767.88E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352622086rs2590838GArs2590838224728769.06E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352626646rs2336146AGrs2336146224728767.38E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352628056rs2577831CArs2577831224728765.11E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352628816rs11714419AGrs11714419224728768.79E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352641255rs3774366TCrs3774366224728766.48E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352642936rs12487591ATrs12487591224728763.09E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352643307rs3733045AGrs3733045224728766.20E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352643685rs3755806TCrs3755806224728763.09E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352649748rs13083798AGrs13083798224728765.83E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352650348rs10510760GArs10510760224728761.14E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352651966rs4687638ACrs4687638224728767.75E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352657002rs13064064TCrs13064064224728763.09E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352659963rs1561337GArs1561337224728762.83E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352663882rs7622694GArs7622694224728766.05E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352668119rs2083180GTrs2083180224728765.04E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352672167rs13068293CArs13068293224728762.90E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352674667rs11130310CTrs11130310224728765.43E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352680823rs2028216CTrs2028216224728768.14E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352682946rs2289250CArs2289250224728762.89E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352683864rs33967311CArs33967311224728762.79E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352692124rs2336149GArs2336149224728764.85E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352692721rs7611731TCrs7611731224728765.00E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352694198rs6804145CTrs6804145224728765.04E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352697163rs11130315AGrs11130315224728763.02E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352698417rs12488461TCrs12488461224728769.12E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352709259rs12496634ACrs12496634224728763.44E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352718280rs10865974GTrs10865974224728768.48E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352719088rs3733039CTrs3733039224728766.05E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352719398rs1866268CArs1866268224728766.51E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352720080rs1108842ACrs1108842224728761.13E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352720080rs11554256AAA,ACrs1108842224728761.13E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352721305rs11177GArs11177224728761.11E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352726695rs6762813CTrs6762813224728761.01E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352727257rs2289247GArs2289247224728766.46E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352728804rs6976CTrs6976224728761.45E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352731269rs2164885TCrs2164885224728767.18E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352731483rs11130317CTrs11130317224728764.83E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352731598rs3733041TCrs3733041224728767.72E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352738165rs12635140TCrs12635140224728761.19E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352739520rs8906TCrs8906224728761.24E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352741160rs3755798GArs3755798224728769.87E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352742413rs34017441TCrs34017441224728766.28E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352748857rs11716747CTrs11716747224728768.61E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352749334rs35526119CTrs35526119224728768.63E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352751534rs7624716TCrs7624716224728767.51E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352764624rs10780035CTrs10780035224728761.39E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352765646rs2079929CTrs2079929224728768.17E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352767427rs767418CTrs767418224728768.03E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352771468rs6445535TCrs6445535224728767.51E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352774530rs2159644CTrs2159644224728767.05E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352778347rs2268026TCrs2268026224728763.41E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352780509rs2072390ATrs2072390224728768.00E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352787603rs2336545TCrs2336545224728765.95E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352793602rs12497998CTrs12497998224728769.23E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352800284rs2230535TCrs2230535224728766.89E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352802402rs2230534ACrs2230534224728766.89E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352804487rs13071584TCrs13071584224728761.05E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352808341rs1014969GArs1014969224728765.55E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352809193rs3755799GArs3755799224728761.08E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352809525rs2019065TCrs2019065224728765.46E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352815905rs2710323TCrs2710323224728761.02E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352817675rs3774354GArs3774354224728765.19E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352818579rs2239551GArs2239551224728763.49E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352821011rs1042779AGrs1042779224728761.02E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352821177rs2286798ACrs2286798224728767.01E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352822921rs2300149CTrs2300149224728766.27E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352823126rs2239549GArs2239549224728764.33E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352823448rs4687551TCrs4687551224728764.04E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352825462rs1076425AGrs1076425224728763.24E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352825528rs1075653TCrs1075653224728763.38E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352825585rs9324TCrs9324224728764.17E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352826276rs2071506TCrs2071506224728763.24E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352826846rs2071508GArs2071508224728764.56E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352828628rs9881468CTrs9881468224728763.68E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352833219rs2535629GArs2535629224728765.88E-09NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352833805rs3617CArs3617224728761.12E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352847601rs2071044CTrs2071044224728761.32E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352852538rs4687657GTrs4687657224728761.79E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352855229rs2239547TCrs2239547224728761.96E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352860936rs2276817CTrs2276817224728763.12E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352864135rs4687554TCrs4687554224728762.74E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352868445rs13083728GArs13083728224728763.40E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352870132rs1573815GArs1573815224728763.25E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352871929rs3733047GArs3733047224728763.30E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352874288rs6445538TCrs6445538224728763.08E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352874296rs6445539GArs6445539224728763.17E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
352889771rs6803519CTrs6803519224728763.25E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
353060637rs2255107CTrs2255107224728764.29E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
353778875rs2253795GTrs2253795224728765.18E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
353788732rs17053472ACrs17053472224728763.01E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
353789172rs719260TCrs719260224728763.27E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
353822893rs3774601GArs3774601224728762.98E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
353824136rs3774604CTrs3774604224728763.61E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
353832712rs3774608GArs3774608224728762.21E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
353832903rs3774609TGrs3774609224728762.16E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
353846741rs877483TCrs877483224728767.46E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
353847062rs893363GArs893363224728761.33E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
359921020rs4502542TCrs4502542227605532.00E-06EA + AA - GSENANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs4502542-T
359924843rs17061517AGrs17061517224728769.42E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
360562327rs17063532GArs17063532229077300.0001157NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
361071811rs9845837GArs9845837224728765.12E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361080782rs1347852GA,C,Trs1347852224728765.59E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361082153rs9825823TCrs9825823224728764.08E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361106321rs7626688TGrs7626688224728768.47E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361111195rs6445194GTrs6445194224728766.04E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361111195rs6445194GTrs6445194232901964.61E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361122318rs9830950CTrs9830950224728761.24E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361132698rs4309721CTrs4309721224728768.14E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361149967rs6807748TCrs6807748224728761.27E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361150158rs11707984CTrs11707984224728761.26E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361153578rs1966136ACrs1966136224728761.37E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361153578rs4020068AAA,ACrs1966136224728761.37E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361155891rs9851485CGrs9851485224728761.46E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361155929rs9871451TCrs9871451224728761.84E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361156905rs1969420TGrs1969420224728761.11E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361159488rs1550343ACrs1550343224728761.87E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361162404rs7631246GTrs7631246224728765.42E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361186550rs9846073TGrs9846073224728765.13E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361187197rs1916800CTrs1916800224728765.46E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361207077rs9843007ATrs9843007224728769.68E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361240793rs9817853TCrs9817853224728766.16E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361241048rs6445200TCrs6445200224728767.36E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361243611rs6785875TCrs6785875224728768.22E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361246997rs7629340GArs7629340224728764.94E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361262149rs815710AGrs815710224728766.26E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
361413814rs10514718CGrs10514718201250884.00E-06NA2.12NA1,020 European cases; 1,636 European controlsEuropean(2656)ALL(2656)EUR(2656)ALL(2656)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs10514718-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
362846109rs581190GArs581190210423174.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
362846109rs581190GArs581190231494480.0000514NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
365013180rs17072107TA,C,Grs17072107208002218.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
365072366rs17342237GArs17342237208002211.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
365083725rs9818174GCrs9818174208002216.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
365100060rs2128405ACrs2128405208002217.27E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
365104040rs17403629AGrs17403629208002216.87E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
366003745rs6762527TCrs6762527208002217.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
366385769rs6793050CArs6793050229077300.0000358NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
366760417rs1379186ATrs1379186208002213.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
369434867rs17005789TGrs17005789210423173.70E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
369554953rs9822785TCrs9822785208002214.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
369555087rs2133343TGrs2133343208002214.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
369555159rs3947355CArs3947355208002215.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
369560235rs1498854CGrs1498854208002216.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
369564625rs9843182AGrs9843182208002216.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
369566966rs1391774CTrs1391774208002216.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
369573402rs1391769TCrs1391769208002216.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
369640802rs7623679GTrs7623679197363533.30E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
370394223rs1090502AGrs1090502216212693.29E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
370394223rs1090502AGrs1090502pha0028508.12E-05phs0000201.34NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
370958673rs17007999AGrs17007999208002218.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
371145830rs2686268ACrs2686268208002219.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
371155250rs3846028TCrs3846028208002212.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
371158354rs831444TCrs831444208002213.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
371283516rs17008389ATrs17008389224728764.26E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
371330949rs1288825CTrs1288825220471846.40E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
371439472rs9815974GArs9815974240474469.66E-06NA1.32NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs9815974-G
371523110rs9819066CTrs9819066229077300.0000682NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
371529915rs6549391ACrs6549391229077300.0001017NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
371530346rs9828629CTrs9828629229077300.0000636NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
371538696rs6549392GTrs6549392229077300.0000735NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
371745012rs17008934AGrs17008934208002218.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
371753949rs13098806TCrs13098806208002211.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
371758197rs13091306TCrs13091306208002219.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
371795224rs11927001AGrs11927001232901963.62E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
371962547rs9832640CTrs9832640208002219.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
372576888rs4677181AGrs4677181229077300.0001999NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
372655715rs13076653CTrs13076653231494480.00000416NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
372657113rs12714788ACrs12714788210423172.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
372657113rs12714788ACrs12714788224728761.97E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
372657311rs17678033TCrs17678033224728762.31E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
372674925rs7637028AGrs7637028224728765.32E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
372675032rs7639455TCrs7639455224728766.34E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
373374442rs4677261TCrs4677261198460675.03E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
373375302rs966163GArs966163198460676.54E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
373376013rs4677262CTrs4677262198460674.69E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
377069266rs4557199TCrs4557199224728761.55E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
382614903rs13079811CArs13079811205161562.69E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
382614903rs13079811CArs13079811229153520.0000034NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<30HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tANA
382614903rs13079811CArs13079811240474463.49E-05NA1.3NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
388414986rs12494959AGrs12494959210423171.00E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
388750857rs6551361TCrs6551361232901966.87E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
388757831rs11927424AGrs11927424232901963.02E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
388758307rs7641985AC,Trs7641985232901963.14E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
388763195rs1587150TArs1587150232901963.27E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
388775481rs1353416GArs1353416232901962.97E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
388786963rs6551366GCrs6551366232901963.66E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
388790882rs17026230GArs17026230232901965.86E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
388793424rs11914750TCrs11914750232901965.58E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
388793982rs2046327CTrs2046327191071151.29E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
389730653rs7628116GCrs7628116232901968.23E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
389731393rs2049103AGrs2049103232901967.68E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
389732392rs7631883GArs7631883232901969.27E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
389733298rs2139686ACrs2139686232901969.53E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
389737061rs7620638AGrs7620638232901968.70E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
389739704rs11923274AGrs11923274232901967.73E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
389759790rs2881577AGrs2881577232901967.94E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
389761271rs7651475CTrs7651475232901967.93E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
389768052rs11917572TCrs11917572232901966.42E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
396085680rs1877807AGrs1877807216212699.81E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
397752197rs6769842AGrs6769842224728764.77E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
397754170rs832067AGrs832067224728765.03E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
397759649rs1694834ATrs1694834224728769.00E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
397766185rs832052AGrs832052224728769.22E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
397771603rs7643404AGrs7643404224728765.63E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
397771736rs861271TGrs861271224728762.13E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
397772007rs832095AGrs832095224728765.41E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3100712249rs3732895TCrs3732895191071156.56E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGABI3BP
3105113237rs4894924TA,Crs4894924213168609.81E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATALCAM
3105246772rs2252459GArs2252459213168608.75E-06Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATALCAM
3109174537rs13314017TCrs13314017208002218.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3109182586rs769529AGrs769529208002218.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3109183295rs769528CGrs769528208002218.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3109193224rs1081119AGrs1081119208002217.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3109194595rs769570AGrs769570208002217.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3109195259rs769566AGrs769566208002217.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111079230rs4611815AGrs4611815208002219.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111080687rs973208TCrs973208208002212.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111081318rs4145123CTrs4145123208002217.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111081455rs4145122TCrs4145122208002217.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111081538rs2958074GCrs2958074208002216.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111086040rs1529058CTrs1529058208002212.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111086732rs6785820GArs6785820208002216.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111087191rs7645369TCrs7645369208002216.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111087564rs7633973CTrs7633973208002216.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111087800rs9843462CTrs9843462208002217.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111089831rs7618272AGrs7618272208002216.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111110391rs1601964TCrs1601964208002212.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111119350rs6778463CTrs6778463208002212.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111124619rs7623819CTrs7623819208002216.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111124985rs1406562TCrs1406562208002212.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111125434rs4682264CTrs4682264208002213.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111127330rs13095499CTrs13095499208002213.00E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111131512rs1391353CArs1391353208002217.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111134809rs1529057ATrs1529057208002213.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111137009rs1391354GTrs1391354208002213.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111141002rs6799452GArs6799452208002212.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111144002rs3902555CArs3902555208002212.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111146775rs2698363GTrs2698363208002218.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111153501rs1909095TCrs1909095208002218.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111157674rs1498004CGrs1498004208002214.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111157773rs1529054AGrs1529054208002213.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111171372rs35655617CACrs7643569208002217.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111171372rs7643569CArs7643569208002217.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111173131rs2698357GArs2698357208002218.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111175311rs2646977GA,C,Trs2646977208002218.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111184140rs1391366CArs1391366208002219.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111197213rs1113850AGrs1113850208002217.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111208529rs2133031CTrs2133031208002219.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3111215119rs13075227TArs13075227208002219.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3115594175rs10511351GArs10511351220599353.06E-04Sudden death suicides with a mood disorder vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
3115594175rs10511351GArs10511351220599356.53E-05Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
3121614489rs1881997TCrs1881997208002218.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3122329160rs2173763AGrs2173763224728766.00E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3124551967rs4141663CTrs4141663229153520.00000456NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tCITGB5
3124610238rs7373878GTrs7373878229153526.49E-08NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tGNA
3125169672rs16836828CTrs16836828200389476.28E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3125309954rs16836892TCrs16836892200389478.52E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3125312100rs16836899CTrs16836899200389479.07E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3125313832rs1055419GArs1055419200389479.76E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
3126298935rs777217CTrs777217200389476.38E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
3126304038rs777230CTrs777230200389479.99E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3126321546rs708908CTrs708908200389473.71E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3126323221rs777228GTrs777228200389477.23E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
3126330242rs777240AGrs777240200389477.48E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
3126330765rs796574AGrs796574200389477.59E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
3126334872rs1716617AGrs1716617200389477.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
3127003972rs9826609CTrs9826609231494480.0000116NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3127616342rs6783960GArs6783960210423178.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3127956272rs2999081AGrs2999081208002218.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129096909rs6791509TCrs6791509208002212.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129099871rs6764325AGrs6764325208002212.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129118583rs16859134TCrs16859134208002212.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129118922rs7622524AGrs7622524208002212.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129122292rs7615711AGrs7615711208002219.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129142951rs4128190CGrs4128190208002212.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129151170rs3138360CTrs3138360208002212.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129195663rs2301570CTrs2301570208002213.91E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129210867rs2285353CArs2285353208002213.27E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129210977rs2285354GCrs2285354208002219.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129212271rs3774769GArs3774769208002213.84E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129250326rs6803484GArs6803484208002219.21E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129262580rs1078507GTrs1078507208002219.65E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3129265192rs6794108AGrs6794108208002213.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3132760219rs2331GArs2331224728769.88E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132760427rs1568478CTrs1568478224728764.88E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132763170rs4854680CArs4854680224728764.97E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132776901rs2049149CTrs2049149224728763.67E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132777314rs9879280TCrs9879280224728764.10E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132784951rs9817813TCrs9817813224728761.74E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132790686rs4496483TGrs4496483224728763.30E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132790857rs4487238CGrs4487238224728761.97E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132792209rs9835480CArs9835480224728761.86E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132794953rs9860508AGrs9860508224728761.99E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132815704rs6807522TGrs6807522224728767.23E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132837238rs16839984TCrs16839984224728761.48E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132841417rs7636123TCrs7636123224728761.96E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132843338rs9864890GArs9864890224728761.99E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3132902053rs12493846GArs12493846220471847.62E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
3132905078rs10460836GTrs10460836220471847.86E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
3133130924rs11708694CArs11708694210423179.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3135028442rs977026CTrs977026208002214.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3135033871rs1445217TCrs1445217208002214.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3136768010rs17374749GArs17374749240474467.00E-06(Dichotomous)1.54NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
3139427206rs12632145CArs12632145216212699.74E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
3141376570rs2640002TCrs2640002208002213.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3143029792rs17574671GArs17574671208002213.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3143032500rs17574746CTrs17574746208002212.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3143037998rs17636943CTrs17636943208002216.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3143044440rs12488603GTrs12488603208002219.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3143086243rs4839627AGrs4839627190651449.10E-07Major depressive disorder (males)NANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
3143100626rs13099124CArs13099124216212692.90E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACSLC9A9
3143126720rs11711068GArs11711068216212695.66E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGSLC9A9
3146391374rs2868452TCrs2868452216212697.41E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
3146391374rs2868452TCrs2868452pha0028503.18E-05phs0000201.33NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNANANA
3150636224rs936189CTrs936189200389473.50E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
3150641304rs1456139GArs1456139200389471.23E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
3152324110rs2141601TGrs2141601224728765.02E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3152328725rs7613502TGrs7613502224728767.24E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3152331312rs11919979AGrs11919979224728764.43E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3152360283rs1540774TCrs1540774224728767.25E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3152364694rs4679989TGrs4679989224728766.77E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3152385748rs9842903CGrs9842903224728767.55E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3152392008rs9878891CA,G,Trs9878891224728766.77E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3153764585rs17817202GTrs17817202208002218.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3155983937rs13081735CArs13081735208002215.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3155994762rs2167144GArs2167144208002215.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3159644297rs6799788AGrs6799788233776401.00E-06partial response - SSRI treated - 2 weeks1.63[1.43-1.82] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs6799788-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3161939907rs10513580TCrs10513580205161564.38E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
3164156963rs9849665GArs9849665213168604.39E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
3166444013rs1517057CTrs1517057200389478.10E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3167076982rs4955621GArs4955621208002216.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3169642073rs1014702GArs1014702208002215.61E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3169643955rs1290670CTrs1290670208002213.61E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3170628770rs6444952TCrs6444952229077300.0002168NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3172091717rs4894544GArs4894544208002217.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3174029045rs13074924AGrs13074924205161569.00E-06NA1.18NA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
3176027779rs1483628TCrs1483628197363533.40E-06Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
3176055539rs2128850CG,Trs2128850216212696.10E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
3176070509rs2626479GArs2626479216212695.64E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
3176647385rs6784900CTrs6784900191071158.51E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
3177211328rs6794095TGrs6794095208002213.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3177223067rs7615202TCrs7615202208002218.67E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3177223930rs13095990CTrs13095990208002212.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3177226809rs6793094ATrs6793094208002212.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3177230565rs6776893TCrs6776893208002213.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3177291697rs644695AGrs644695200389475.00E-06NA1.35NA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionrs644695-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
3177591074rs10936959AGrs10936959213168604.85E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
3179706448rs1522116CTrs1522116232901963.69E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3183858939rs865808ACrs865808224728766.91E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3183864863rs863615GArs863615224728768.61E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3183876512rs1969253ACrs1969253224728765.00E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3184838045rs7619914CTrs7619914224728764.23E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3184853342rs9841506AGrs9841506224728769.70E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3184875154rs4419361AGrs4419361224728762.25E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3184876783rs7647854GArs7647854210423175.00E-06NA1.19NA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs7647854-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3184876783rs7647854GArs7647854224728766.51E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3184876783rs7647854GArs7647854232901964.60E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3185563274rs2098771GArs2098771216212699.29E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
3185801628rs7433760AGrs7433760205161568.12E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyG
3186939573rs3914010AGrs3914010208002211.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187413991rs6764050GArs6764050227605539.00E-07EA + AA - GSENANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs6764050-G
3187632238rs9810106GCrs9810106208002213.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187963313rs12629148CGrs12629148208002215.40E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187971048rs9844029TCrs9844029208002212.30E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187979323rs9838939GTrs9838939208002212.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187985004rs715790CTrs715790208002212.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187986617rs6807582CTrs6807582208002214.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187987726rs13066827AGrs13066827208002211.00E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187988025rs16848776CTrs16848776208002214.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187989520rs6444273TArs6444273208002214.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187989686rs6444274AGrs6444274208002213.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187991205rs6762523AGrs6762523208002213.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3187995779rs6779331AGrs6779331208002214.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3188000625rs9839229TCrs9839229208002211.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3188001875rs11713973TCrs11713973208002211.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3189231017rs6444381CGrs6444381208002215.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3189239766rs1895664GArs1895664208002217.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3191818642rs4585146GArs4585146233776403.00E-07% improvement - SSRI treated - 2 weeks0.22[0.14-0.31] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs4585146-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3191818642rs4585146GArs4585146233776406.00E-06% improvement - 2 weeks1.16[1.11-1.22] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs4585146-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3193533201rs1392705AGrs1392705224728763.22E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3193583710rs604222GArs604222233776407.00E-06% improvement - SSRI treated - 2 weeks0.22[0.12-0.31] unit increaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs604222-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
3193651300rs4687470TCrs4687470208002219.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3193653537rs2636914TCrs2636914208002219.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
3193955440rs4349452GArs4349452216212692.32E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAALOC100505920
3195174420rs10933645AGrs10933645213168602.43E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
4803637rs28504502CTrs28504502224728765.58E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
43252852rs3129322TCrs3129322224728762.35E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
47592068rs4594727TGrs4594727229077300.0000793NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
47592068rs4594727TGrs4594727229077300.0001292NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
47607757rs757240AGrs757240229077300.0000533NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
47610540rs16840617AGrs16840617229077300.0000405NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
411159968rs11724374GArs11724374224728766.96E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
411303176rs4697869AGrs4697869210423177.20E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
412025870rs9998636GCrs9998636208002213.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
412108239rs4834882TCrs4834882224728762.04E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
412119860rs6856121CGrs6856121224728761.15E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
412124104rs1479255TCrs1479255224728761.30E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
412125014rs7662249GArs7662249224728761.52E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
412138827rs1382751CTrs1382751224728764.66E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
412182361rs2127270TGrs2127270197363533.40E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
413095942rs16902AGrs16902208002215.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413096420rs555931TArs555931208002211.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413096599rs559930TCrs559930208002211.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413097600rs479731TCrs479731208002211.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413097877rs481820CTrs481820208002214.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413098110rs503461CTrs503461208002214.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413098267rs504503TCrs504503208002214.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413098882rs512244CTrs512244208002214.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413099268rs536973ATrs536973208002214.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413099886rs543108GArs543108208002214.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413100779rs495276TCrs495276208002214.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413113491rs11723376CTrs11723376208002218.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413116762rs491376GCrs491376220414582.00E-06Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers491376-C
413122535rs573332CTrs573332220414581.00E-06Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers573332-G
413897193rs1606083AGrs1606083208002215.10E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
413899000rs807773TArs807773208002213.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
414179198rs3111816AGrs3111816232901963.04E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
414179729rs1426134CGrs1426134232901963.78E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
415938392rs16892645CTrs16892645208002219.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
415995125rs17387100AGrs17387100217507029.53E-06Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tAPROM1
416104538rs1040206TGrs1040206216212691.60E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
416123232rs317887GArs317887208002216.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
418862247rs6856020CTrs6856020216212691.47E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
418908518rs6449435CTrs6449435216212697.88E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
424215917rs16875349TCrs16875349216212699.53E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
424232087rs10938982GArs10938982216212691.53E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
424740958rs12500612GTrs12500612233776407.00E-06partial response - 2 weeks1.77[1.51-2.02] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs12500612-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
427964405rs11934750ATrs11934750245282841.00E-07(S-DCT/S-CT ratio, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralT
433624702rs10517287GTrs10517287220414582.00E-07Citalopram+Bupropion, Vision/hearingNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers10517287-T
437532743rs7687449TCrs7687449208002218.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
438927230rs9999294AGrs9999294210423171.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
441176071rs12331383GArs12331383200389475.62E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
441181161rs7659645CTrs7659645200389475.45E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
441193113rs11932112ACrs11932112200389473.87E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
444633416rs4694776GArs4694776198460674.74E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tAYIPF7
444871784rs10517121AGrs10517121229077300.0002606NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
453758005rs4864692TCrs4864692208002213.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
454569983rs2668537AGrs2668537208002219.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
454571229rs2616390TCrs2616390208002213.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
454572883rs2668539AGrs2668539208002217.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
454574146rs2668540CArs2668540208002213.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
454574365rs2590786GArs2590786208002214.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
454576884rs1871028CArs1871028208002214.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
454581890rs2616398AGrs2616398208002214.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
454582974rs1993838CTrs1993838208002214.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
458933336rs166583AGrs166583191071159.80E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
458983189rs1824388TCrs1824388198460674.52E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNA
469795359rs3749514AGrs3749514220471845.13E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469820283rs7679122CArs7679122220471848.69E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469824923rs11249517GArs11249517220471848.24E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469825314rs2199040CTrs2199040220471848.79E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469828352rs17147042GA,Crs17147042220471847.53E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469828352rs372606092GGCrs17147042220471847.53E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469830054rs2331564CGrs2331564220471846.99E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469830542rs3966085GArs3966085220471847.59E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469832315rs1598903AGrs1598903220471847.67E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469832836rs3886643TCrs3886643220471843.53E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469833007rs3886642CTrs3886642220471841.52E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469833909rs1458230ATrs1458230220471842.46E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469837898rs7695476TCrs7695476220471842.82E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT,C
469839734rs1458229AGrs1458229220471842.37E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469847013rs1841039CTrs1841039220471842.20E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469852666rs10447083CTrs10447083220471848.73E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469853849rs4590113GArs4590113220471849.49E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469853973rs4467643GTrs4467643220471848.97E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469859025rs1841055ACrs1841055220471849.06E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469866445rs1841051GTrs1841051220471848.93E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469878038rs17146872GArs17146872220471847.33E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469883217rs4604120TArs4604120220471847.78E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469887437rs4235106GArs4235106220471847.10E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469891169rs7441736CTrs7441736220471843.34E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469893854rs4235108GArs4235108220471843.36E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469894731rs4305590ACrs4305590220471844.31E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469897813rs4326076AGrs4326076220471841.46E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469899513rs6827511TCrs6827511220471843.44E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469901663rs13147648TCrs13147648220471843.47E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469902422rs4353969AGrs4353969220471843.48E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469903001rs13102620ATrs13102620220471843.48E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469903744rs4495114TCrs4495114220471843.48E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469903924rs4299665AGrs4299665220471843.48E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469905257rs4235111GArs4235111220471843.48E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469908707rs13140844ATrs13140844220471843.44E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469911197rs4518318CTrs4518318220471848.95E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469916384rs7438808GTrs7438808220471845.91E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469917073rs4377650CTrs4377650220471848.69E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469922387rs4583828CTrs4583828220471849.82E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
469926623rs3922514CTrs3922514220471846.44E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
469927974rs7662632TCrs7662632220471844.55E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT,C
469936933rs4400060TCrs4400060220471844.49E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469936999rs4400061TCrs4400061220471844.48E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469937046rs4446390GArs4446390220471844.48E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
469941154rs12648830CArs12648830220471842.81E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469941191rs7677996CTrs7677996220471845.37E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469944942rs4694610CGrs4694610220471842.91E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469945009rs7657426CTrs7657426220471842.59E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
469988999rs12645107GArs12645107220471845.98E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
470352266rs1826690AGrs1826690210423171.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
470474310rs6832167GArs6832167191071151.32E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAA,GUGT2A1
472136575rs1377287AGrs1377287217507024.87E-06Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTSLC4A4
476812031rs17001163TCrs17001163208002211.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
476812673rs13116688CGrs13116688208002215.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
476817221rs10007472TCrs10007472208002211.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
476818367rs13147538AGrs13147538208002212.01E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
476819485rs1847731TCrs1847731208002219.06E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477528821rs11723275ACrs11723275208002215.30E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477536598rs3733247GArs3733247208002217.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477538555rs4859697CArs4859697208002212.06E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477542398rs7669852GArs7669852208002215.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477545018rs4330370GTrs4330370208002212.55E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477549559rs6838801GTrs6838801208002219.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477551310rs7695340CTrs7695340208002212.68E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477552782rs4582178AGrs4582178208002219.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477553691rs6818060GArs6818060208002219.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477560635rs17322488GArs17322488208002211.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477560811rs17322529AGrs17322529208002211.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477582838rs7680223ACrs7680223208002212.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477591448rs13134149AGrs13134149208002212.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477595358rs7695034ATrs7695034208002213.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477610963rs4475167GCrs4475167208002216.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477616748rs4124581GArs4124581208002213.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477619296rs344117TCrs344117208002212.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
477678728rs344126GArs344126208002214.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
479324480rs12643648TC,Grs12643648205161562.23E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyG
482462597rs1822818TCrs1822818233776406.00E-06partial response - SSRI treated - 2 weeks1.77[1.53-2.02] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs1822818-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
483596745rs10030631TCrs10030631210423175.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
484562362rs1458642TGrs1458642213168604.61E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
485165195rs17008878GArs17008878220471844.29E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485165381rs348701GArs348701220471842.21E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
485174676rs17008416GArs17008416220471846.80E-07Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485174971rs17008418GCrs17008418220471846.97E-07Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485176082rs13131541TCrs13131541220471849.95E-07Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
485179393rs13107419TCrs13107419220471849.45E-07Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
485180049rs13108923TCrs13108923220471849.43E-07Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
485180857rs1495142GArs1495142220471849.41E-07Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485182881rs13124982ATrs13124982220471841.27E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
485184515rs1596144GArs1596144220471841.28E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
485188394rs1390086TCrs1390086220471841.29E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
485189712rs1495140GArs1495140220471841.47E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
485190648rs1495138CGrs1495138220471841.48E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485192989rs13131476GArs13131476220471841.55E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485195715rs17008469GArs17008469220471841.55E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
485197642rs1992467GArs1992467220471841.92E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485198099rs2165618ACrs2165618220471841.91E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
485203880rs13122718CTrs13122718220471842.24E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
485204621rs6858150CTrs6858150220471846.91E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
485206085rs13141237AGrs13141237220471842.23E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
485214642rs17008523GTrs17008523220471841.72E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485229612rs1472292AGrs1472292220471845.39E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
485239755rs7694261TGrs7694261220471842.99E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485240664rs7654197TCrs7654197220471848.95E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
485241536rs7660492TCrs7660492220471849.16E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
485243537rs7673792TCrs7673792220471843.70E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
485244005rs6535533AGrs6535533220471849.63E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485244426rs6832343AGrs6832343220471843.84E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
485248800rs17008585TCrs17008585220471843.54E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
485249352rs17008592ATrs17008592220471843.57E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
485249751rs17008601CTrs17008601220471843.57E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
485261370rs1822222TCrs1822222220471843.95E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT,C
485262808rs6857631GArs6857631220471849.64E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
485263676rs11945202CTrs11945202220471849.35E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
485265750rs6841642GArs6841642220471849.74E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
485268820rs1899391CTrs1899391220471849.35E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
485268860rs1899392GArs1899392220471849.68E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
485271434rs17008637GTrs17008637220471849.33E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
485898741rs4590017GArs4590017191071158.28E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGWDFY3-AS2
485915570rs4533765CTrs4533765191071153.45E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACWDFY3-AS2
486604729rs7698203TGrs7698203229077300.0001728NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
486703976rs10516756TCrs10516756213168603.50E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATARHGAP24
486966103rs6810413GArs6810413224728761.47E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
486967830rs10028075CTrs10028075224728762.05E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
486983232rs3775187TCrs3775187224728761.71E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
486990027rs1469869CA,G,Trs1469869224728761.67E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
486998264rs13112959TGrs13112959224728761.97E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
487001823rs9995879CTrs9995879224728762.16E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
487011304rs4482754GArs4482754224728761.34E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
487014806rs12502934CGrs12502934224728761.91E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
487019238rs9884770AGrs9884770224728762.14E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
487021938rs12644947GArs12644947224728765.04E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
490135739rs538005CTrs538005200389475.45E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
490155732rs1431555TCrs1431555200389474.47E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
490157051rs12500719GArs12500719200389474.44E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
490164136rs6532144TCrs6532144200389474.65E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
490169925rs7653897AGrs7653897200389474.99E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
490172722rs4270553ATrs4270553200389477.80E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
490173451rs13126986TCrs13126986200389477.35E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
490174346rs13106955GCrs13106955200389477.52E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
490174968rs17825868TCrs17825868200389477.47E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
490175113rs1125861AGrs1125861200389477.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
490178067rs13142984CGrs13142984200389475.84E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
490178131rs13118995TCrs13118995200389477.78E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
490178671rs13149373CTrs13149373200389478.28E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
490180437rs6532149ACrs6532149200389478.49E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
490180489rs7690986GArs7690986200389478.91E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
492734290rs1485991CTrs1485991224728763.42E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
492734718rs17018779TCrs17018779224728763.28E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
493480717rs7663643CTrs7663643200389477.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
493481256rs7689379TGrs7689379200389475.27E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
493484718rs921354TArs921354200389475.19E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493487336rs6532376GArs6532376200389473.74E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493487465rs6532377CArs6532377200389475.00E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493490985rs7695324GArs7695324200389474.61E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493492008rs12501529CTrs12501529200389474.52E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
493498569rs11935893GTrs11935893200389474.29E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
493499118rs16996340AGrs16996340200389476.33E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493499842rs6829672ACrs6829672200389474.15E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
493499992rs6830091CTrs6830091200389474.01E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
493500669rs17019608CArs17019608200389473.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493502067rs7686627GTrs7686627200389474.09E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
493502127rs7686323AGrs7686323200389473.56E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
493503156rs6851143CArs6851143200389473.51E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493504230rs9685970TCrs9685970200389474.11E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
493505257rs17019639CTrs17019639200389474.89E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
493506449rs10856895TCrs10856895200389476.87E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
493506614rs12500504AGrs12500504200389471.92E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493508342rs10516910AGrs10516910200389472.86E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493508367rs17019672TArs17019672200389472.31E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
493509159rs7663835GArs7663835200389472.66E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493527235rs12643761GArs12643761200389477.71E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493528040rs7672511GArs7672511200389475.34E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493539640rs201034095TTTCrs7693534200389479.75E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
493539640rs7693534TCrs7693534200389479.75E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
493557939rs6532378GArs6532378200389479.88E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493564740rs12641482TCrs12641482200389479.83E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
493578229rs1479325GTrs1479325200389479.83E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
493584189rs10012693CGrs10012693200389479.79E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
495562877rs17021918CTrs17021918229077300.0000928NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
495589477rs3762876AGrs3762876229077300.0000508NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
495608023rs6532503GTrs6532503224728762.71E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4103377576rs1313925TCrs1313925191071157.93E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
4106005247rs10008015CTrs10008015229077300.0001989NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4106390734rs2298733ACrs2298733191071153.53E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATPPA2
4108105844rs12511906GArs12511906231494480.00000195NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4108374237rs11733491TCrs11733491220471846.24E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
4112201846rs17576345CTrs17576345200389479.66E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4113302869rs7673053TGrs7673053229153520.000005NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tGALPK1
4114703773rs10461151AGrs10461151229077300.0001578NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4119800081rs6534110TCrs6534110216212696.22E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
4122663430rs6815973TArs6815973208002217.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4122695888rs6534323GArs6534323208002213.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4124081430rs1025286GTrs1025286224728761.75E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4125265313rs2125000CTrs2125000233776403.00E-06remission - 12 weeks1.43[1.27-1.58] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs2125000-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4125415534rs6534441CTrs6534441233776407.00E-06% improvement - SSRI treated - 12 weeks0.18[0.1-0.26] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs6534441-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4125462793rs975107TCrs975107229077300.0002277NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4127563253rs12509148ATrs12509148208002216.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4127580129rs372903CTrs372903208002212.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4127588709rs313076TArs313076208002215.18E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4127656069rs1167190AGrs1167190229077300.0001688NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4128434334rs2203374GCrs2203374200389475.71E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4129303760rs291079CTrs291079208002213.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4129307717rs7654743AGrs7654743208002218.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4129310867rs7674959CGrs7674959208002216.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4129311823rs3870129TCrs3870129208002214.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4130139735rs6854308CTrs6854308208002217.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4130194362rs13119203GArs13119203200389473.11E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4130233602rs11735407TGrs11735407208002218.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4131091376rs7656732CTrs7656732229077300.0000846NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4131162995rs10028531CTrs10028531229077300.0001301NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4131169265rs7437554AGrs7437554229077300.000108NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4131174088rs12506063TCrs12506063229077300.0001154NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4131174088rs12506063TCrs12506063229077300.0002121NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4131174498rs11099042GArs11099042229077300.0001301NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4131175071rs6833836AGrs6833836229077300.0001301NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4131495706rs2085679AGrs2085679213168604.74E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
4131499397rs1968821AGrs1968821213168601.83E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
4131499397rs1968821AGrs1968821213168609.31E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
4131502194rs2311375GArs2311375213168606.51E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATNA
4137021516rs12511521GArs12511521224728762.17E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4137312423rs2192204TGrs2192204198460671.29E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNA
4138416511rs9761827GArs9761827229077300.0000227NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4138464842rs7439567CTrs7439567229077300.00000311NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4138464842rs7439567CTrs7439567229077300.0001303NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4138464842rs7439567CTrs7439567229077300.0001303NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4139385626rs11736129CGrs11736129208002216.93E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4145517578rs2353397CTrs2353397216212695.15E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
4145517578rs2353397CTrs2353397pha0028507.05E-05phs0000201.22NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNANANA
4148322929rs17023187TCrs17023187217507022.53E-05Suicidal ideation and behaviour in major depressive disorder (SCAN Suicidality (SSU) score)NANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTNA
4149090326rs4835490GArs4835490229077300.0000495NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4149090326rs4835490GArs4835490229077300.0001452NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4154104459rs4543093AGrs4543093200389479.31E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4154113457rs12511084CArs12511084200389479.50E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4157185914rs17034315TGrs17034315200389473.00E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4159332036rs11931209ATrs11931209237266682.00E-04NA1.67[1.32-2.13]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4159365684rs2346793GTrs2346793237266682.00E-04NA1.67[1.30-2.13]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4159377474rs10032252GArs10032252237266683.00E-04NA1.64[1.28-2.08]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4162312156rs2314133GArs2314133224728761.09E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4164617856rs1039959GCrs1039959220599352.94E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG,C
4166575899rs764240GArs764240224728761.49E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4166578236rs2611209GTrs2611209224728762.91E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4172914208rs956998AGrs956998216212699.35E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATGALNTL6
4174758521rs6820522CArs6820522210423173.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4174761895rs11133017GArs11133017210423173.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4174766775rs12505092CGrs12505092210423172.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4174777578rs13138013CTrs13138013210423172.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4174786039rs13107098CTrs13107098210423174.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4175935746rs12640583GTrs12640583208002217.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4175936475rs13111482GArs13111482208002217.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4175936490rs6553853CArs6553853208002217.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4175936529rs6824013AGrs6824013208002216.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4175939626rs12513233GArs12513233208002217.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4175940265rs13129897AGrs13129897208002216.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4175940831rs13141617TGrs13141617208002217.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4175948807rs12509972CArs12509972208002217.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4175950930rs1479385CArs1479385208002219.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4175952615rs12640173CTrs12640173208002215.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4175960753rs13106889TArs13106889208002219.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4176949041rs7659781TCrs7659781220471841.30E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
4177895429rs13104005CTrs13104005208002212.83E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4177901883rs1865744CArs1865744208002219.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4177905575rs13143572ACrs13143572208002212.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4177925312rs1125172CArs1125172208002213.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4179604212rs346101GArs346101200389476.69E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4179606545rs12506809GArs12506809200389477.84E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
4179607090rs406797TCrs406797200389476.71E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT,C
4179608992rs13136757CTrs13136757200389479.54E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4179612707rs6827191TGrs6827191200389479.43E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
4180669418rs10520433TCrs10520433240474461.21E-05NA1.64NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
4181886803rs1969401CTrs1969401208002217.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4183030136rs6815885GArs6815885220471843.99E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
4183033029rs1458893CTrs1458893220471843.56E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
4183904055rs4862135AGrs4862135208002219.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
4184053187rs11132168CTrs11132168190651442.90E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
4184053187rs11132168CTrs11132168pha0028506.29E-05phs0000201.33NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACWWC2intronNM_024949
4184277307rs17074631AGrs17074631190651444.00E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
4184277307rs17074631AGrs17074631216212694.09E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
4185127217rs2310001TCrs2310001213168604.43E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACENPP6
4185728839rs902177TCrs902177210423176.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4186501965rs2310320TCrs2310320197363533.40E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
4187338335rs11935103CTrs11935103227605531.00E-06EA + AA - GSENANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs11935103-T
4187338335rs11935103CTrs11935103227605532.00E-06EA - GSENANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression casesNOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs11935103-T
4187411620rs6854525AGrs6854525224728763.57E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4188190117rs6553051CTrs6553051210423172.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4188190117rs6553051CTrs6553051224728762.06E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4188190219rs6553052GTrs6553052210423173.50E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4188190219rs6553052GTrs6553052224728761.75E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4188191306rs4478239CArs4478239210423172.70E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4188191306rs4478239CArs4478239224728765.00E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4188191516rs4478240CTrs4478240210423171.50E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4188191516rs4478240CTrs4478240224728762.01E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4188201350rs4862792TGrs4862792224728762.09E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4188225183rs6832990GArs6832990224728766.85E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4189036322rs13116982GArs13116982205161563.13E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
4189188713rs111874200GArs111874200245282843.56E-07(S-DCT/S-CT ratio, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
4189188765rs10024857GA,Trs10024857245282843.92E-07(S-DCT/S-CT ratio, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG,A
4189189463rs11725970AGrs11725970245282844.94E-08(S-DCT/S-CT ratio, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
4189191111rs71607999GArs71607999245282847.00E-09(S-DCT/S-CT ratio, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
4189191166rs11736476GArs11736476245282843.28E-08(S-DCT/S-CT ratio, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
4189194478rs13115076CTrs13115076245282842.22E-07(S-DCT/S-CT ratio, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
4189195068rs13121835GArs13121835245282846.02E-07(S-DCT/S-CT ratio, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
4189196141rs13129087CTrs13129087245282842.81E-07(S-DCT/S-CT ratio, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
4189203711rs9790703TCrs9790703245282848.90E-08(S-DCT/S-CT ratio, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralT
4189792991rs6828833CTrs6828833224728769.31E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
4190319160rs1456348CGrs1456348220471842.93E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
4190333556rs2085363ACrs2085363220471843.25E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
590199rs341260TCrs341260229077300.0002312NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
51496622rs36991CTrs36991224728768.63E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
51691202rs1875196CGrs1875196224728764.71E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
53171701rs13171158AGrs13171158200389472.15E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
53211391rs421093TCrs421093216212695.27E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
53714522rs2398624CArs2398624208002217.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
53765311rs13436004TCrs13436004208002217.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
53848856rs2963790TCrs2963790213168603.61E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
55575229rs16875765AGrs16875765210423177.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
58213918rs13170406GCrs13170406208002218.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58214073rs10037687GArs10037687208002218.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58214218rs10035204AGrs10035204208002218.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58214296rs10038291GArs10038291208002218.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58214344rs10038296GArs10038296208002218.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58214841rs11134297AGrs11134297208002218.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58214996rs11134298CArs11134298208002218.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58215104rs12521845CTrs12521845208002218.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58215439rs4702534CArs4702534208002218.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58218692rs4701804TCrs4701804208002217.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58218718rs4701805CTrs4701805208002217.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58219678rs4702536GArs4702536208002219.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58226339rs6892570GTrs6892570208002217.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58228502rs6874030GArs6874030208002217.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58232117rs6555529TGrs6555529208002218.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
58233974rs2087291ATrs2087291208002219.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
59413495rs448038ACrs448038237266685.51E-05NA2.82[1.75-4.57]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionrs448038-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
510148156rs7443032TGrs7443032220471845.88E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
513846802rs17208191TGrs17208191210423175.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
516184180rs342559GArs342559229077300.000107NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
516812638rs17651119CTrs17651119233776402.00E-08% improvement - 12 weeks3.18[2.77-3.59] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs17651119-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
518007227rs505682AGrs505682240474461.07E-05NA1.31NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs505682-A
518568081rs12697189TCrs12697189208002214.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
518570590rs12656579GArs12656579208002214.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
518578054rs12654064CTrs12654064208002219.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
518579606rs12658762GTrs12658762208002219.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
519433362rs346775CGrs346775208002212.54E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
519440168rs349475TCrs349475208002212.00E-06NA0.18[NA] unit increase3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs349475-TMeta-AnalysisResearch Support, N.I.H., Intramural
519440168rs349475TCrs349475232901962.40E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
519441735rs10520861TCrs10520861208002216.93E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
519446308rs623213CArs623213208002215.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
519446761rs621084GArs621084208002213.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
519448955rs1707015TCrs1707015208002212.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
519454083rs12055355GCrs12055355208002211.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
519454190rs349455TCrs349455208002212.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
521027996rs17239680AGrs17239680208002216.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
522522625rs1948748TCrs1948748229077300.0001156NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
522533473rs1477441CTrs1477441229077300.0002167NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
522756398rs17358685GArs17358685216212696.47E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGCDH12
522756398rs17358685GArs17358685pha0028507.51E-05phs0000201.23NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGCDH12intronNM_004061
525091472rs10942087CTrs10942087232901966.33E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525092432rs2047268ACrs2047268232901966.36E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525092779rs12654558CTrs12654558232901966.45E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525092994rs12657561TCrs12657561232901966.55E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525093717rs995431TArs995431232901967.00E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525095178rs12521551AGrs12521551232901967.90E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525095635rs12519063CTrs12519063232901968.64E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525097916rs11746102AGrs11746102232901969.74E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525097969rs7728789CTrs7728789232901969.97E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525303740rs6875442CArs6875442232901966.01E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525315404rs13163964GArs13163964232901966.80E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525315980rs4627955GArs4627955232901966.43E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525326757rs13157155GCrs13157155232901966.38E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
525543266rs1428241TCrs1428241229077300.000031NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
527611431rs12054895GTrs12054895233776403.00E-08% improvement - SSRI treated - 2 weeks0.24[0.16-0.33] unit increaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs12054895-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
528017816rs1546138CArs1546138208002213.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
528086068rs17531726TCrs17531726208002214.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
528340173rs11949289GArs11949289220414582.00E-07Venlafaxine, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers11949289-T
529513178rs329882AGrs329882208002217.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
529515854rs624343CTrs624343208002213.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
529518942rs636643GArs636643208002214.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
529520477rs788542CGrs788542208002212.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
529604899rs4331915AGrs4331915197363534.20E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
531766433rs2059865TArs2059865245282843.00E-07(S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
531766703rs10461903TCrs10461903245282845.99E-07(S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralT
531781647rs34884728GArs34884728245282844.33E-07(S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
531789679rs7707966CTrs7707966245282845.10E-07(S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
531812179rs13182171ACrs13182171245282848.02E-07(S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
531813639rs34301697AGrs34301697245282848.42E-07(S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
532766822rs3811966TCrs3811966220599354.38E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
536196428rs7716788GArs7716788220471849.44E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
537409579rs13178300CTrs13178300229077300.0002196NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538046009rs7722472CTrs7722472200389474.50E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538051241rs16903843TCrs16903843200389477.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538051593rs270545GArs270545200389473.39E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538051593rs270545GArs270545201250881.00E-06NA1.37NA1,020 European cases; 1,636 European controlsEuropean(2656)ALL(2656)EUR(2656)ALL(2656)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs270545-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538051703rs6897687TCrs6897687200389475.08E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538052046rs270543GArs270543200389473.41E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538052113rs10073812CTrs10073812200389475.76E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538053333rs270538AGrs270538200389473.77E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
538053488rs270537AGrs270537200389473.64E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
538054327rs6883823TCrs6883823200389475.27E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538055273rs270599CArs270599200389474.50E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538056271rs169187AGrs169187200389474.97E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
538056753rs10512674ACrs10512674200389476.74E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538057728rs270596CTrs270596200389475.32E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538058518rs1729011GArs1729011200389475.28E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538058559rs1703301CTrs1703301200389475.40E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538058965rs6867522TCrs6867522200389477.11E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538059375rs6891116CArs6891116200389475.89E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538060688rs270594TCrs270594200389475.94E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538063061rs368758GArs368758200389477.55E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538066586rs270592GArs270592200389471.88E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538074854rs270584CArs270584200389472.06E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538078180rs270578AGrs270578200389471.51E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538085159rs1874170TGrs1874170200389478.89E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
538087078rs2471046CArs2471046200389479.10E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538087361rs2453332AGrs2453332200389479.20E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
538087397rs2471047TCrs2471047200389479.33E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538087767rs1817900AGrs1817900200389479.36E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538087810rs1817901AGrs1817901200389479.43E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
538088411rs2453333TCrs2453333200389479.59E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538088444rs2471049AGrs2471049200389479.72E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538088520rs2471050TCrs2471050200389477.74E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538089107rs12653109TCrs12653109200389479.76E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538089284rs2463769AGrs2463769200389479.55E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538089427rs2453335ATrs2453335200389479.53E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538090175rs2471052TCrs2471052200389479.54E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538090806rs4413560GCrs4413560200389479.71E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538091354rs2471070TCrs2471070200389479.72E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538091684rs2471074CTrs2471074200389479.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538094717rs2463765AGrs2463765200389473.99E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
538094871rs2453338ATrs2453338200389471.69E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
538095315rs2471065GTrs2471065200389471.93E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
538452894rs7715172CGrs7715172227605533.00E-06EA + AA - GSENANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs7715172-G
540227586rs351651GArs351651198460671.35E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNA
540775297rs3792822CTrs3792822210423179.80E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
540790551rs10074991GArs10074991210423177.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
540791884rs13361707CTrs13361707210423176.80E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
540997614rs1878291GArs1878291208002215.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
540999419rs896117GArs896117208002214.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541001023rs2167229GArs2167229208002218.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541004807rs2305314CTrs2305314208002213.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541005791rs10941529TCrs10941529208002212.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541006488rs13155319GArs13155319208002212.05E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541006951rs10805656GArs10805656208002212.06E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541009282rs10061334GArs10061334208002211.98E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541009899rs1878290AGrs1878290208002212.01E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541010731rs962274ATrs962274208002212.04E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541011187rs1160833TCrs1160833208002212.05E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541013467rs12054764ATrs12054764208002212.08E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541014117rs2876851GTrs2876851208002211.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
541018452rs10054110ATrs10054110208002212.04E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
551746682rs10045166TCrs10045166191071158.96E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
551819014rs4296761GArs4296761191071159.53E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
551861437rs10512971AGrs10512971205161563.34E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
551861437rs10512971AGrs10512971224728769.29E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
554317900rs6891823CTrs6891823224728767.48E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
554322476rs1848502CGrs1848502231494480.0000463NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
554327955rs2112938GTrs2112938216212694.17E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACGZMK
554428310rs10043664CArs10043664205161564.59E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
559139938rs17371592TCrs17371592208002219.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
559154182rs13175506GArs13175506208002219.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
559232230rs10069878TCrs10069878231494480.0000634NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
562538957rs17481124CGrs17481124208002215.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
562549356rs10939962TCrs10939962208002218.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
562614342rs11950497AGrs11950497208002211.64E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
564680267rs9291836TCrs9291836230914230.000002NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564688741rs7708972GArs7708972230914230.0000019NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564688741rs7708972GArs7708972230914230.00000249NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564697866rs10042191TCrs10042191230914230.00000103NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564707040rs10069691CArs10069691230914230.00000143NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564708119rs9291837GCrs9291837230914230.00000212NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564725524rs10072030AGrs10072030230914230.00000233NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564726440rs1493451CTrs1493451230914230.00000235NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564730851rs6449784TCrs6449784230914230.00000205NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564733927rs2047064AGrs2047064230914230.00000204NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564734702rs7728131GArs7728131230914230.00000216NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564735540rs6876189GArs6876189230914230.0000018NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564740765rs7705423CArs7705423230914230.00000174NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564745925rs2131587CTrs2131587230914230.00000153NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
564749723rs7725105CArs7725105230914230.00000171NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
566277028rs2888109TGrs2888109230914230.00000467NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Norepinephrine reuptake inhibitors (NRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
567240236rs9291908TCrs9291908197363536.20E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
568455166rs389686CTrs389686208002217.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573802976rs1001114AGrs1001114208002218.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573803417rs737541AGrs737541208002215.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573807043rs1651352AGrs1651352208002214.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573810372rs298366CGrs298366208002214.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573810478rs212925TCrs212925208002214.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573816110rs186139TCrs186139208002214.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573817655rs186140TCrs186140208002213.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573821242rs298393CTrs298393208002213.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573828332rs298403CTrs298403208002214.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573829775rs298407CTrs298407208002214.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573831661rs298410AGrs298410208002214.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573831867rs167232CArs167232208002213.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573833731rs1651350GCrs1651350208002214.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
573835470rs1651348GTrs1651348208002213.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
574954633rs253411ATrs253411220471841.33E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
574955841rs253412GArs253412220471841.06E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
574956517rs253414CTrs253414220471841.02E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
574965122rs34358GArs34358220471843.62E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
574965554rs42302AGrs42302220471842.03E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
574967386rs40060CTrs40060220471841.98E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT,C
574967693rs34359GCrs34359220471841.97E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
574967708rs34360CArs34360220471841.97E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
574982207rs16872768TCrs16872768220471841.50E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
574997756rs10057967TCrs10057967220471841.30E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
574999576rs6874626GArs6874626220471841.32E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
575003056rs3797580AGrs3797580220471841.16E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
575015242rs2112347TGrs2112347220471841.53E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
575023210rs6453143GCrs6453143220471843.00E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
575030034rs7730516GArs7730516220471843.63E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
575034387rs7715806CTrs7715806220471845.75E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
575038718rs258494CGrs258494220471841.80E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
576311858rs13178527TCrs13178527200389476.08E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
576805269rs2359879CArs2359879205161562.12E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
577769002rs10065805CGrs10065805197363531.10E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
577783089rs1050674GCrs1050674197363532.00E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
578100800rs16875947ATrs16875947230914230.00000098NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Norepinephrine reuptake inhibitors (NRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
578102483rs7711802GArs7711802230914230.00000105NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Norepinephrine reuptake inhibitors (NRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
578103605rs16876279CTrs16876279230914230.00000098NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Norepinephrine reuptake inhibitors (NRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
578728923rs7719054TCrs7719054197363532.90E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
578829249rs7713917AGrs7713917206738761.00E-06NA1.33[1.19-1.49] 597 German cases; 1,295 controlsNOPOP(1295)German(597)ALL(1892)NOPOP(1295)EUR(597)ALL(1892)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs7713917-GResearch Support, Non-U.S. Gov't
579088995rs2287673AGrs2287673216212693.31E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATCMYA5
579106163rs17471700ACrs17471700200389477.11E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
579106163rs17471700ACrs17471700216212691.73E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
582889910rs310501GArs310501205161567.00E-06NA1.16NA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyG
585635829rs7700535CGrs7700535224728768.24E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
587034352rs1673101GArs1673101233776404.00E-06% improvement - SSRI treated - 2 weeks0.19[0.11-0.27] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs1673101-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
587081822rs16902806GArs16902806208002215.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
587082276rs710375CTrs710375208002214.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
587082947rs710374TCrs710374208002216.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
587083187rs710373CTrs710373208002215.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
587086974rs11740855TCrs11740855208002215.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
587087913rs16902816GArs16902816216212695.63E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
587089786rs16902819GArs16902819208002214.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
587138466rs1345818CTrs1345818216212695.19E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
587397560rs6877822AGrs6877822216212696.61E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
589111529rs1363179TGrs1363179232901968.05E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
589113060rs1421908CTrs1421908232901968.25E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
591324764rs9293596TCrs9293596208002216.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
591938390rs2221271AGrs2221271210423175.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
591938705rs1393221TCrs1393221210423174.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
592588151rs4632782GTrs4632782208002217.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
594405027rs890294TCrs890294229077300.000191NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
594428936rs11960770GArs11960770229077300.0001179NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
596658577rs7733541ACrs7733541240474464.05E-05(Dichotomous)1.44NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs7733541-C
5103723455rs1530303CTrs1530303232901968.68E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103736802rs13162928TCrs13162928232901968.04E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103737890rs13181679GArs13181679232901967.15E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103745044rs13177473AGrs13177473232901964.75E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103750804rs1583953CTrs1583953232901964.37E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103757005rs768792AGrs768792232901964.45E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103766154rs2028526TCrs2028526232901965.31E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103771206rs1442111GTrs1442111232901963.26E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103771766rs2919955GArs2919955232901963.12E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103771888rs920623GArs920623232901963.71E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103810310rs6881764GArs6881764232901967.48E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103889998rs1592757GCrs1592757232901961.05E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103902161rs1421669GCrs1421669232901961.47E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103927579rs2447838CTrs2447838232901961.63E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103933473rs2447832CTrs2447832232901962.05E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103936343rs254035TArs254035232901962.01E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103943938rs254025CGrs254025232901962.87E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103945178rs2161097CTrs2161097232901963.43E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103946482rs2112163CTrs2112163232901963.62E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103947205rs2447828CTrs2447828232901963.51E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103950251rs254020CTrs254020232901962.94E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103955361rs254023TCrs254023232901963.11E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103965223rs185260ACrs185260232901962.71E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103978326rs33817GArs33817232901962.38E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103981726rs40465TGrs40465232901964.78E-08NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5103995368rs325485AGrs325485232901965.42E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5104000752rs325481GArs325481232901964.27E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5104007433rs325501GCrs325501232901964.19E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5104012303rs325506CGrs325506232901966.81E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5104042643rs113164363AACrs1976423232901965.82E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5104042643rs1976423ACrs1976423232901965.82E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5104069917rs161645AGrs161645232901968.00E-08NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs161645-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5104075130rs6421926TCrs6421926232901969.96E-08NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5104078233rs60271ACrs60271232901962.54E-07NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5104106441rs13155692TCrs13155692232901963.18E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5105022790rs1480583CTrs1480583216212695.97E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
5105065177rs1383370TArs1383370216212698.79E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
5109946411rs4277958GArs4277958208002213.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5110075414rs665063CArs665063208002214.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5110076352rs12187004AGrs12187004208002214.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5110080363rs244923TCrs244923208002215.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5110085742rs6892259ACrs6892259208002212.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5110089350rs12522587CArs12522587208002213.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5110093673rs4957918CA,G,Trs4957918208002211.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5111083884rs3797734TArs3797734208002212.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5111084118rs17133711ACrs17133711208002218.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5111084245rs17133713TCrs17133713208002213.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5111089355rs17133719AGrs17133719208002218.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5111893547rs7378714GTrs7378714229077300.0000464NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
5114952645rs2052834GArs2052834210423172.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5115007424rs424347CTrs424347210423178.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5115030677rs166082ACrs166082210423178.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5115050362rs251891GTrs251891210423176.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5115150525rs26531TGrs26531224728766.59E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5116218278rs253890CTrs253890205161568.57E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyT
5117254988rs4365869ATrs4365869216212696.83E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
5118617170rs4895363TCrs4895363224728762.44E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5123131879rs11746266GArs11746266229077300.0001934NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
5123832652rs12513663CTrs12513663233776402.00E-06% improvement - 2 weeks1.18[1.11-1.26] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs12513663-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5128730528rs10053585GTrs10053585208002216.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5128838809rs10058781CTrs10058781208002219.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5128846774rs1363145AGrs1363145208002219.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5133303819rs13169435CTrs13169435208002216.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5134443606rs254560GArs254560240474464.96E-05(Dichotomous)1.41NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs254560-A
5134550729rs10076673CGrs10076673208002212.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5134633657rs10515470TGrs10515470220599353.81E-04Sudden death suicides with a mood disorder vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5134633657rs10515470TGrs10515470220599354.62E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5140723174rs3806837TCrs3806837216212696.77E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGPCDHGA2
5141210753rs166040AGrs166040233776405.00E-06partial response - 2 weeks1.61[1.41-1.80] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs166040-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5143117818rs167801GArs167801208002219.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5143125856rs325239GArs325239208002216.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5143126090rs325238CTrs325238208002216.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5143127750rs325235CTrs325235208002214.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5143128591rs325232CTrs325232208002214.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5143130044rs325229GCrs325229208002212.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5143130488rs6580301GArs6580301208002212.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5143130523rs6580302GArs6580302208002212.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5143131673rs2636103CTrs2636103208002213.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5143173023rs833748CTrs833748208002219.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144461281rs1422839CGrs1422839208002215.84E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144511211rs12652320AGrs12652320208002217.72E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144763704rs7444042ATrs7444042208002218.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144765247rs282461CGrs282461208002217.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144766803rs32196AGrs32196208002218.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144768423rs32193GArs32193208002211.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144768513rs32192CTrs32192208002211.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144768756rs32191CTrs32191208002211.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144769376rs32190TCrs32190208002215.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144773424rs282457TCrs282457208002218.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144777730rs32200TCrs32200208002212.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144779164rs7736243ATrs7736243208002211.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144782381rs711171CArs711171208002211.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144782407rs813188ACrs813188208002211.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144786806rs1086849CGrs1086849208002213.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144793716rs796940CArs796940208002215.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144806973rs6875732TArs6875732208002211.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144807446rs6886139AGrs6886139208002211.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144807495rs17475118TCrs17475118208002211.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144809625rs1946246GArs1946246208002215.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144810692rs7721549GArs7721549208002211.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144812693rs10515550CTrs10515550208002211.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144812772rs11949093AGrs11949093208002211.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144813876rs365874CTrs365874208002215.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144817144rs415600TArs415600208002214.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144819407rs433924CTrs433924208002213.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144843397rs2431606AGrs2431606208002213.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144845050rs2974572GArs2974572208002213.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144846633rs2974571GArs2974571208002213.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144849242rs2910271TGrs2910271208002213.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144851525rs2910272AGrs2910272208002213.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5144855438rs118978CA,G,Trs118978208002212.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5149036976rs17710780TCrs17710780233776404.00E-06remission - 12 weeks1.66[1.45-1.88] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs17710780-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5149275457rs17110665TArs17110665224728763.25E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5150751378rs10515648GArs10515648208002218.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150760877rs11741064CTrs11741064208002218.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150764714rs7702931CTrs7702931208002216.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150766681rs17802576TArs17802576208002215.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150767778rs11742559CGrs11742559208002215.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150768279rs17740447CTrs17740447208002215.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150777798rs11167544GArs11167544208002213.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150789173rs7713313GArs7713313208002213.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150794323rs17740556AGrs17740556208002213.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150794720rs17740573TGrs17740573208002213.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150795336rs11167546CArs11167546208002215.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150795813rs12658833TCrs12658833208002215.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150795975rs17740585CGrs17740585208002215.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150797895rs2161224AGrs2161224208002216.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150799295rs11747813TCrs11747813208002216.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150799529rs17802762CTrs17802762208002218.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150800243rs17740620CTrs17740620208002219.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5150831642rs4958272GTrs4958272224728767.89E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5152993589rs2910268GTrs2910268208002213.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5153009489rs1422884TCrs1422884208002217.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5153017520rs1422892ACrs1422892208002218.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5154448739rs351294CTrs351294229077300.000074NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
5154489437rs1008795CTrs1008795208002215.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5154493253rs7703759AGrs7703759208002216.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5154493531rs13155597CArs13155597208002216.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5154496941rs1005789AGrs1005789208002217.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5154498866rs7703459CTrs7703459208002215.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5154499570rs7728292TCrs7728292208002214.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5154500533rs6873028AGrs6873028208002214.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5154505490rs1564885CTrs1564885208002216.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5155049324rs11951343CTrs11951343197363534.40E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
5156920756rs1990950GTrs1990950210423174.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5159007778rs10065906CArs10065906233776402.00E-06partial response - SSRI treated - 2 weeks1.53[1.36-1.70] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs10065906-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5159007778rs10065906CArs10065906233776405.00E-08partial response - 2 weeks1.47[1.33-1.61] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs10065906-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5159732687rs17057624TArs17057624220471845.51E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
5159733561rs13155668GCrs13155668220471847.62E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
5163267157rs7713437AGrs7713437232901969.68E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5163273413rs6895949GArs6895949232901968.50E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5164481996rs4077278CGrs4077278232901968.56E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5164759496rs10515893GArs10515893230914230.00000093NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5164759496rs10515893GArs10515893230914230.00000137NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5167534846rs6866450AGrs6866450208002219.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5167535028rs6867056GTrs6867056208002219.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5167784624rs2059090GArs2059090191071152.30E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACWWC1
5169359960rs194787CTrs194787197363539.20E-06Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
5169872420rs6872566AGrs6872566208002218.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5170149554rs2277951TCrs2277951208002214.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5170157819rs11134647TArs11134647208002217.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5170159072rs4867628TCrs4867628208002215.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5170163908rs1363714AGrs1363714208002217.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5170167013rs4867629CArs4867629208002213.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5170167974rs1363715GArs1363715208002217.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5170973103rs9790986CGrs9790986208002215.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5173183362rs2122003CTrs2122003224728762.21E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
5173806074rs2936953TGrs2936953213168602.60E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
5173839160rs718927GArs718927213168605.71E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
5174832789rs6873756CTrs6873756208002214.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
5177753208rs11948332GCrs11948332216212699.61E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGCOL23A1
6398775rs2671422GArs2671422229077300.0002503NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
61783630rs3800065GArs3800065208002211.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
64962641rs1246938GArs1246938208002217.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
64973677rs17285799CTrs17285799208002214.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
66612467rs2326810GCrs2326810200389477.00E-06NA1.41NA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionrs2326810-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
66614742rs9392815GTrs9392815200389472.46E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
67248459rs2094012CTrs2094012224728767.87E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68390967rs1199388AGrs1199388200389474.81E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
68607128rs9405400AGrs9405400210423173.50E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68620503rs6597343TCrs6597343210423173.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68632793rs7765238CGrs7765238210423173.80E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68635572rs7762631AGrs7762631210423173.70E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68637501rs7753781CTrs7753781210423173.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68638036rs1328870GArs1328870210423172.50E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68639771rs9406183GTrs9406183210423173.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68653247rs7763881ACrs7763881210423173.50E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68659071rs9328500GCrs9328500210423174.00E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68659904rs7739573CTrs7739573210423173.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68662608rs11243268GA,Trs11243268210423173.30E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
68948459rs10458233CTrs10458233208002219.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
68949924rs12208641TGrs12208641208002219.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
68950441rs13211231AGrs13211231208002219.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
610033326rs12209628TCrs12209628232901968.67E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
610033433rs12205387CTrs12205387232901968.72E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
610176036rs12210761GArs12210761233776406.00E-06partial response - SSRI treated - 2 weeks2.45[2.06-2.83] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs12210761-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
610324531rs10456010GArs10456010229077300.0001055NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
610474951rs470382TArs470382198460675.59E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
611173821rs9468537TCrs9468537231494480.0000469NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
611808064rs7743245CTrs7743245229077300.0001942NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
611811314rs3950186CTrs3950186240474468.00E-06NA1.32NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs3950186-T
611818316rs1883326CTrs1883326229077300.0001963NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
611825414rs1569731AGrs1569731229077300.0002197NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
613564003rs12663015CTrs12663015200389478.84E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
614278169rs6917540AGrs6917540200389472.88E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
614282023rs12526133CTrs12526133200389475.87E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
614289082rs2094923TGrs2094923190651444.20E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
614289082rs2094923TGrs2094923200389473.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
614289082rs2094923TGrs2094923pha0028502.89E-05phs0000201.23NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
614291089rs2274822TCrs2274822190651447.00E-06Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
614291089rs2274822TCrs2274822216212691.57E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
614291089rs2274822TCrs2274822pha0028501.56E-05phs0000201.27NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
616256043rs10484358GTrs10484358233776401.00E-06% improvement - SSRI treated - 2 weeks0.43[0.25-0.6] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs10484358-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
616511362rs3806136TCrs3806136220471849.95E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
616772225rs628059TCrs628059210423177.20E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
616772252rs628021CTrs628021210423177.40E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
616773382rs602206CTrs602206210423174.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
616774161rs598948CTrs598948210423176.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
616777131rs528785AGrs528785210423172.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
617913077rs1014146GTrs1014146216212698.78E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACKIF13A
619628340rs2328483AGrs2328483229077300.0001162NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
619628633rs6930954TGrs6930954229077300.0001413NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
619629346rs4452635TCrs4452635229077300.0001008NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
621233903rs10755611AGrs10755611220471846.57E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
623841132rs9466930CGrs9466930233776404.00E-06remission - 12 weeks1.5[1.32-1.68] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs9466930-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
624022898rs16888503TCrs16888503229077300.0002566NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
626341062rs9358929GArs9358929210423178.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
626388672rs1796518CTrs1796518208002211.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
626947474rs12212302TGrs12212302200389471.57E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
626948174rs10946885AGrs10946885200389478.80E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
626948195rs4713062CTrs4713062200389477.35E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
626951678rs10946888TCrs10946888200389476.62E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
626965139rs2754603TCrs2754603200389474.62E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
626965897rs12201034TCrs12201034200389475.89E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
626973215rs10946891TCrs10946891200389475.85E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
626975690rs12201393CArs12201393200389475.84E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
626990358rs10456352ATrs10456352200389475.75E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
626998567rs4358615AGrs4358615200389474.46E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
627000236rs6937880CTrs6937880200389476.05E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
627006475rs12527111CTrs12527111200389475.99E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
627007113rs11756275GTrs11756275200389476.39E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
627009512rs7775041TArs7775041200389475.51E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
627017827rs6918835TGrs6918835200389475.43E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
627036456rs4424065CTrs4424065200389471.00E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
627047256rs6904071GArs6904071224728764.06E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
627047713rs994691ATrs994691200389475.88E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
627053142rs6930508TCrs6930508200389474.73E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
627057518rs7451149TCrs7451149200389474.92E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
627059443rs926300ATrs926300232901969.12E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
627066163rs9379958ACrs9379958200389472.56E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
627070543rs6456767CTrs6456767200389475.80E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
627080460rs2393915ACrs2393915200389477.07E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
627093821rs6456768GCrs6456768200389477.38E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
627143883rs13194053TCrs13194053224728763.64E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
627217719rs9393795GCrs9393795200389479.19E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
627287800rs12174489CTrs12174489200389472.65E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
627866823rs6900413GArs6900413232901961.18E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
627869321rs1873213TGrs1873213232901966.05E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
627870772rs9468252AGrs9468252232901968.42E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
628216027rs2235358AGrs2235358210423178.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
628358195rs2859379CTrs2859379224728761.79E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
630166935rs2072107GArs2072107224728765.97E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
630185244rs9261567TCrs9261567224728768.33E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
630323623rs3094626TCrs3094626208002214.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
630797991rs7749924CTrs7749924224728765.94E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
630982544rs9394026GArs9394026210423174.90E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
630993590rs12179536AGrs12179536210423176.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
631327064rs2523590TCrs2523590224728769.10E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
631604355rs35502919CArs35502919210423171.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
631682029rs805284GArs805284210423178.20E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
632429643rs9268853TCrs9268853210423178.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
632429758rs9268858TCrs9268858210423178.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
632429758rs9268858TCrs9268858231494480.0000859NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
632433167rs2395185GTrs2395185210423176.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
632438542rs9368726TCrs9368726210423177.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
632438648rs9405108CTrs9405108210423177.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
632599999rs9272105GArs9272105210423179.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
632602269rs9272219GTrs9272219210423178.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
632611641rs9273012AGrs9273012210423178.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
632823393rs241420CA,G,Trs241420200389475.40E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
633570075rs510153GArs510153217507021.42E-05Suicidal ideation and behaviour in major depressive disorder (SCAN Suicidality (SSU) score)NANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNA
635592744rs7748266TCrs7748266213168609.23E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACFKBP5
635621781rs9394309GArs9394309213168601.58E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAAFKBP5
635646435rs9470080TCrs9470080213168601.00E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATFKBP5
637533294rs11751671GArs11751671224728762.96E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
638723161rs2206860TGrs2206860213168607.09E-06Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACDNAH8
639230307rs1182864GArs1182864229077300.0000404NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
639230571rs4711589ACrs4711589229077300.0000382NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
639289875rs1109798GArs1109798229077300.0001932NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
640494855rs7356878TGrs7356878229077300.0001796NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
640503796rs1433742GTrs1433742229077300.0001812NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
641361012rs640399GArs640399224728765.56E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
642915920rs6941212TCrs6941212197363531.30E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
644065311rs7742824GArs7742824233776409.00E-06% improvement - 2 weeks1.19[1.11-1.26] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs7742824-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
646128794rs2235882CTrs2235882229077300.0001967NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
646580382rs3799872GArs3799872191071151.46E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATCYP39A1
646582156rs7758684GTrs7758684191071155.71E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATCYP39A1
647086952rs937055TCrs937055232901961.99E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
647089544rs1687119AGrs1687119232901964.51E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
647094118rs1687128GTrs1687128232901964.05E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
647094552rs1738819CTrs1738819232901969.57E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
647213859rs4482973GTrs4482973208002214.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
651370293rs6902578ACrs6902578220471842.26E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
652800648rs6917307ATrs6917307210423175.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
652801687rs364932CTrs364932210423175.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
653281511rs1401160TCrs1401160200389479.51E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
653291466rs6458934GArs6458934200389474.73E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
653291576rs7744451TArs7744451200389473.12E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
653292013rs4715392ATrs4715392200389475.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
653292425rs1401159TCrs1401159200389476.31E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
653293410rs4440459TGrs4440459200389475.21E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
653294553rs1401158ATrs1401158200389473.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
653295907rs9395864GArs9395864200389475.18E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
653296156rs9370209AGrs9370209200389475.55E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
653883843rs17625497GArs17625497220471842.75E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
653903152rs9637973GArs9637973210423172.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
653904347rs1325831TCrs1325831210423172.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
653921127rs9474720ACrs9474720210423177.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
653924697rs9296736TCrs9296736210423173.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
655590730rs9357875ACrs9357875210423172.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
655596618rs9382550CTrs9382550210423173.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
655598297rs9349791ACrs9349791210423173.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
655607390rs2145898TCrs2145898210423173.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
664014812rs9352774ACrs9352774216212699.53E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAALGSN
664094892rs1525361TCrs1525361224728764.62E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
664101818rs1723527AGrs1723527200389473.67E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
664589465rs1482463CTrs1482463231494480.0000813NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
667171922rs1513498GArs1513498224728767.74E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
667635684rs4257844TCrs4257844198460677.38E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tTNA
674521787rs1501192TCrs1501192232901968.72E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
674982166rs9359077TCrs9359077200389473.58E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
675031230rs4708146GCrs4708146200389476.18E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
677436710rs9352377CArs9352377200389476.19E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
678111780rs1738519CArs1738519231494480.0000607NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
678184375rs1936158GTrs1936158229077300.0000689NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
678184375rs1936158GTrs1936158229077300.0001893NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
678294880rs1902970GArs1902970229077300.0001209NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
678350842rs1379887CTrs1379887229077300.00000788NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
678350842rs1379887CTrs1379887229077300.00000905NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
678350842rs1379887CTrs1379887229077300.00000905NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
678351916rs898040GArs898040229077300.0000167NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
678351916rs898040GArs898040229077300.0000169NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
678351916rs898040GArs898040229077300.0000181NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
678381834rs9343638GArs9343638229077300.0000499NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
678381834rs9343638GArs9343638229077300.0000717NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
678494764rs17777705CTrs17777705229077300.0000762NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
678494764rs17777705CTrs17777705229077300.000124NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
678547147rs9361296ACrs9361296229077300.0000912NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
678547147rs9361296ACrs9361296229077300.0001435NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
678562076rs1877531TCrs1877531229077300.0000624NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
678562076rs1877531TCrs1877531229077300.0000865NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
678614862rs7738598CArs7738598229077300.0000162NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
678614862rs7738598CArs7738598229077300.0000166NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
678614862rs7738598CArs7738598229077300.0000167NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
678614862rs7738598CArs7738598229077300.0000167NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
678620417rs12189558GArs12189558229077300.0002311NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
678639575rs2207343TA,Grs2207343198460672.99E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tTNA
678655699rs9294091CTrs9294091229077300.0000573NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
678655699rs9294091CTrs9294091229077300.0001741NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
678655840rs9294092GCrs9294092198460671.85E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
678678184rs6941223TCrs6941223198460671.27E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
678697736rs9352550GArs9352550229077300.000101NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
678699746rs12206418GTrs12206418198460672.84E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNA
678699763rs12192878AGrs12192878198460675.35E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
678708695rs6932080CTrs6932080198460672.23E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
678719322rs9350746GArs9350746229077300.0000752NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
678719322rs9350746GArs9350746229077300.0001499NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
680527555rs10806179ACrs10806179205161562.75E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
680606507rs10943676GTrs10943676197363534.20E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
680843956rs2322631ACrs2322631229077300.0001139NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
680854470rs10080237TCrs10080237229077300.0001139NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
680959912rs978814CArs978814229077300.0000382NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
680959912rs978814CArs978814229077300.0002081NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
680968727rs3812121AGrs3812121229077300.0000494NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
681025879rs9352817TGrs9352817229077300.000067NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
681478607rs10485285GArs10485285229077300.0000675NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
681648445rs534800AGrs534800229077300.0002016NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
689293745rs12527253AGrs12527253208002214.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
690651086rs3734662CTrs3734662217507021.15E-04Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tABACH2
691504562rs11759332CTrs11759332208002216.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
691975997rs7740461TCrs7740461208002217.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
691976164rs7758710AGrs7758710208002218.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
692022715rs9342272CTrs9342272208002213.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
692024031rs9353821CArs9353821208002213.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
692031699rs6906049GArs6906049208002213.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
692041904rs2144363ACrs2144363208002212.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
692042794rs9294486CTrs9294486208002212.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
692045007rs9353823GCrs9353823208002212.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
692076041rs9345131GCrs9345131208002214.12E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
692076091rs9362869TCrs9362869208002214.06E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
692086552rs9342276GArs9342276208002213.79E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
694389460rs13208357CTrs13208357208002216.17E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
694404170rs10944690TArs10944690208002215.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
694408714rs6933279GArs6933279208002214.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
697500047rs12195230GCrs12195230208002218.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
697501957rs1737659TCrs1737659208002219.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
697502496rs1737660TArs1737660208002219.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
697503734rs12206420CTrs12206420208002217.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
697504652rs1737661CTrs1737661208002217.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
697504706rs9320403GArs9320403208002216.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
697508981rs1206118TCrs1206118208002215.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
697509164rs946117GArs946117208002215.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
699551970rs10457592GArs10457592224728765.27E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6102218731rs1325060AGrs1325060208002219.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6103801640rs1155126CArs1155126197363534.00E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
6104128743rs7743180TGrs7743180224728764.84E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6104352616rs10214527GTrs10214527213168602.00E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANANANA
6104784819rs270678CTrs270678217507021.94E-04Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTNA
6104817775rs17459015TCrs17459015217507021.63E-04Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTNA
6107639608rs2500584TCrs2500584198460679.93E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGPDSS2
6110245755rs4947035GArs4947035229077300.0000369NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
6110424341rs3828927TCrs3828927229077300.0002483NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6110502831rs7761436AGrs7761436229077300.0002495NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
6114408925rs9488322TCrs9488322200389471.00E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
6114429171rs1855625GTrs1855625200389479.34E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6114800377rs6568842AGrs6568842210423172.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6117769728rs9489193TCrs9489193191071154.75E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
6117787897rs7749229CTrs7749229191071157.38E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
6117793798rs2104064TCrs2104064191071159.23E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
6117799572rs7746536ACrs7746536191071151.06E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
6117814437rs13195478GArs13195478191071154.90E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGDCBLD1
6117885959rs12194183CTrs12194183191071151.47E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACGOPC
6117994158rs13211542GArs13211542191071151.63E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
6119451332rs706981AGrs706981208002214.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6119455554rs10457349ACrs10457349208002213.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6119460747rs9385067GArs9385067208002213.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6119462950rs9387636CArs9387636208002213.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6119463018rs706983TCrs706983208002213.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6119463757rs9401129GArs9401129208002213.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6119465611rs6934752CGrs6934752208002217.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6119466590rs7775389GArs7775389208002217.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6119466737rs9387637GArs9387637208002218.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6119467331rs9398502CTrs9398502208002219.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6119468457rs6928078TGrs6928078208002215.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6120892849rs9482055GArs9482055191071157.36E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
6120911731rs962312AGrs962312191071158.72E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
6124396177rs17086573TGrs17086573210423175.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6124396731rs9320975TGrs9320975210423175.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6128593134rs6923988ACrs6923988197363531.90E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
6129141297rs6569558AGrs6569558229077300.0002262NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
6129718493rs41524649TArs41524649198460679.76E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tALAMA2
6129887299rs17810534TCrs17810534230914230.0000028NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6129912799rs10499161AGrs10499161230914230.00000401NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6130216510rs9375674AGrs9375674229077300.000151NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
6131030583rs9483167GArs9483167208002216.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6131046403rs4897449AGrs4897449208002212.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6131046661rs4897450ACrs4897450208002212.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6131046822rs4897451CTrs4897451208002212.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6131047288rs4897455AGrs4897455208002212.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6131052404rs4112310CArs4112310208002211.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6131052657rs1497885CArs1497885208002211.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6131052657rs1497885CArs1497885216212695.68E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
6131054125rs10457556AGrs10457556208002211.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6131055104rs9388836GArs9388836208002218.74E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6131095477rs728263CTrs728263208002211.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6132687293rs17061204TGrs17061204213168607.01E-06Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATMOXD1
6134721958rs6932621GArs6932621224728768.84E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136259596rs1418340CGrs1418340224728761.27E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136262043rs883799CTrs883799224728761.92E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136265021rs9376168GArs9376168224728762.29E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136265165rs7774640GArs7774640224728761.95E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136266316rs2327665CGrs2327665224728769.42E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136271527rs2018448AGrs2018448224728769.55E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136276087rs10872455AGrs10872455224728766.50E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136281844rs4896187GCrs4896187224728767.15E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136284331rs12190806TCrs12190806224728767.50E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136284476rs11154835GArs11154835224728769.00E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136288944rs4896189AGrs4896189224728761.29E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136311863rs4254999ACrs4254999224728769.87E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136317656rs4896192GArs4896192224728762.10E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136332358rs9376172TCrs9376172224728766.79E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136333229rs9402782GArs9402782224728767.61E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6136336210rs9399177CTrs9399177224728768.76E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6138606252rs203136TGrs203136217507021.74E-07Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCKIAA1244
6139413936rs2473509AGrs2473509220471847.69E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
6140016409rs9376452CTrs9376452208002212.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140023968rs12055436TCrs12055436208002213.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140024345rs17069225TCrs17069225208002213.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140025377rs12055472TGrs12055472208002213.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140033527rs2185923CArs2185923208002219.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140040671rs12663299TCrs12663299208002213.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140042495rs7752001GArs7752001208002219.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140046410rs9376457GArs9376457208002219.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140046629rs9389715AGrs9389715208002219.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140049600rs10452652CArs10452652208002219.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140238780rs12524396CTrs12524396208002217.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140260472rs9484329AGrs9484329208002215.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140263141rs1028471CTrs1028471208002214.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140264234rs1572674CArs1572674208002214.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6140312592rs10499215CTrs10499215208002218.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6143057591rs7762241GCrs7762241208002219.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6143083063rs638880GTrs638880208002216.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6145201896rs11968590AGrs11968590197363531.50E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
6145626208rs9386110TCrs9386110197363534.10E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
6148126416rs949073GArs949073208002219.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6148127584rs6941498AGrs6941498208002219.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6148778680rs9322150AGrs9322150220471845.54E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
6148827807rs1147865TGrs1147865208002219.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6149172368rs4361637TCrs4361637220471846.79E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
6149311607rs2486404ACrs2486404203603151.73E-08NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6149312334rs2500525TCrs2500525203603151.74E-08NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6149313157rs2486403AGrs2486403203603151.88E-08NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6149314291rs2486402AGrs2486402203603153.70E-08NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6149318799rs2486398TCrs2486398203603157.91E-08NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6149320283rs2500530ATrs2500530203603157.95E-08NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6149320682rs2486397CGrs2486397203603157.97E-08NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6149321746rs2486396CTrs2486396203603157.99E-08NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6149324196rs2486390TCrs2486390203603158.05E-08NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6149329267rs2500535AGrs2500535203603154.00E-08nortriptyline27NA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abusers2500535-AResearch Support, Non-U.S. Gov't
6149329267rs2500535AGrs2500535203603159.00E-06genotype x drug29.7NA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abusers2500535-AResearch Support, Non-U.S. Gov't
6149329267rs2500535AGrs2500535230914230.0006NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Norepinephrine reuptake inhibitors (NRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6149336009rs2486416CTrs2486416203603155.59E-08NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6149336177rs2486415GArs2486415203603156.25E-07NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
6150868815rs9372072CGrs9372072208002218.14E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6152700965rs13220008AGrs13220008224728763.97E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152712752rs214944CTrs214944224728763.26E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152714446rs20585CArs20585224728762.81E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152714606rs1203233GTrs1203233224728762.16E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152719218rs522437CGrs522437224728763.36E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152722228rs177330AGrs177330224728764.73E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152722715rs214952ACrs214952224728761.02E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152727331rs127196CArs127196224728762.29E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152728814rs544863CArs544863224728761.57E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152731398rs214978ACrs214978224728767.74E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152733593rs214987GArs214987224728761.19E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152751558rs553642CTrs553642224728769.67E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152752324rs525210TCrs525210224728766.64E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152760906rs215001GArs215001224728764.72E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152762589rs214997AGrs214997224728769.63E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152766186rs214993GArs214993224728767.25E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152768194rs527021CTrs527021224728766.21E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152768796rs502268TGrs502268224728766.17E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152772264rs214976AGrs214976224728762.52E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152774033rs70018GArs70018224728763.04E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152775232rs169974TCrs169974224728762.59E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152776331rs214969GCrs214969224728762.08E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152782933rs579464GArs579464224728762.08E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152789197rs7756410AGrs7756410224728761.88E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152790573rs9371601GTrs9371601224728762.95E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152792213rs4318888TCrs4318888224728761.99E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152797065rs9397510GArs9397510224728769.26E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152797353rs7751588CTrs7751588224728767.85E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152802209rs7740022CTrs7740022224728762.34E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152802297rs7763880TCrs7763880224728766.36E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152805889rs9397512CTrs9397512224728767.16E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152810721rs9397518CTrs9397518224728768.15E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152826222rs9371604TArs9371604224728763.60E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152838121rs2449116ATrs2449116224728762.78E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152842018rs2623981CTrs2623981224728762.61E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6152848898rs2623932AGrs2623932224728769.73E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6153096503rs1410489GTrs1410489200389478.82E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
6153164323rs13208658GArs13208658200389471.61E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
6153168437rs13219094TCrs13219094200389472.17E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6153175131rs13199515GCrs13199515200389474.61E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
6153187682rs13194909TGrs13194909200389475.45E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6153198982rs13203493ATrs13203493200389475.38E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
6153213122rs13196491TCrs13196491200389478.33E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6153315921rs3799133GArs3799133200389471.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6153333328rs650018AGrs650018224728761.03E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6153333550rs503366TCrs503366224728761.15E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6154554607rs17292684ACrs17292684224728767.90E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6155560480rs3935935CTrs3935935220471845.27E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
6155579400rs3822964AGrs3822964220471848.88E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
6155581024rs1408756GTrs1408756220471849.04E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
6155582350rs2281838GArs2281838224728763.18E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6155642564rs324368AGrs324368224728762.66E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6157108163rs6927409TCrs6927409208002215.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6157255918rs284418AGrs284418208002219.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6157290122rs6420142TCrs6420142208002219.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6158041283rs2163287GArs2163287220414583.00E-06Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers2163287-A
6160384403rs6934383AGrs6934383191071157.89E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
6161675491rs3798943TCrs3798943240474468.00E-06(Dichotomous)1.45NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
6161706942rs1972203AGrs1972203198460674.86E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNA
6161722057rs7760006AGrs7760006198460675.25E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNA
6162093021rs9355357TCrs9355357229077300.000208NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tNA
6163634122rs7776125TCrs7776125208002216.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6163718869rs12055671TCrs12055671200389477.31E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6163719115rs6927758CTrs6927758200389479.48E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6164008112rs12208278GArs12208278210423172.70E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6164900598rs4709845GArs4709845205161569.00E-06NA1.21NA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyG
6165467714rs9295300AGrs9295300240474461.97E-05(Quantitative)0.44[NA] unit decrease1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs9295300-G
6166064152rs9365900GArs9365900232901966.05E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6166686875rs10946146CGrs10946146224728765.16E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6166761245rs9457165TCrs9457165229077300.0000916NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
6168685533rs9346682AGrs9346682224728764.14E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
6168698932rs12204529CGrs12204529208002213.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6168700040rs3800537AGrs3800537208002211.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6168700846rs12202943GArs12202943208002213.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6168704707rs11757729GCrs11757729208002215.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6168774529rs1886399TCrs1886399208002215.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6168784850rs4708462TGrs4708462208002216.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6168786135rs4285297TCrs4285297208002215.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6169009635rs16887198TCrs16887198208002217.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6169009688rs13206739CGrs13206739208002215.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6169009874rs6455538AGrs6455538208002217.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6169052936rs11751354CTrs11751354216212697.16E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATSMOC2
6170365244rs11753156CTrs11753156208002211.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6170374026rs9460193CTrs9460193208002212.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
6170385304rs9348346ATrs9348346208002212.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
73049009rs10236776AGrs10236776210423174.30E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
73713194rs13223746TGrs13223746198460676.17E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tTSDK1
74030435rs750291CTrs750291210423176.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
74033680rs1025914GArs1025914210423177.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
74038917rs6950410CTrs6950410210423171.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
74042436rs6462522CTrs6462522210423171.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
78786057rs886505AGrs886505197363537.40E-06Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
79017053rs17157938GCrs17157938208002214.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
710186070rs12534108GCrs12534108216212692.48E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
711284015rs13230115AGrs13230115208002214.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
711383755rs10232201AGrs10232201220471849.89E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
711385184rs6953611GCrs6953611220471844.62E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
712596616rs11764174TCrs11764174200389476.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
712602211rs10276226AGrs10276226208002214.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
712604609rs6954578CGrs6954578208002215.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
712606847rs1859989CGrs1859989208002215.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
712606852rs1859990AGrs1859990208002215.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
715000298rs36909ATrs36909208002219.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
715000305rs36910GArs36910208002215.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
715001308rs36914GArs36914208002218.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
715008959rs217607AGrs217607208002213.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718714254rs17139571TGrs17139571220471846.15E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
718718573rs4484585CArs4484585220471846.74E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
718730268rs17139658TCrs17139658220471848.60E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
718891259rs13245206GArs13245206208002217.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718898305rs6461387GArs6461387208002217.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718903015rs756854CTrs756854208002218.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718907030rs6461389CTrs6461389208002213.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718908850rs6973029CTrs6973029208002212.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718910232rs6461390AGrs6461390208002212.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718911789rs6951144CGrs6951144208002215.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718911957rs6951745GArs6951745208002213.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718912802rs6461392GArs6461392208002214.01E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718912815rs6461393TGrs6461393208002213.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718912890rs6461394CGrs6461394208002214.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718913380rs7794241CArs7794241208002212.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718914251rs2286213CGrs2286213208002213.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718915426rs10237149GArs10237149208002212.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718915559rs10237366GCrs10237366208002212.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718915666rs10237280CTrs10237280208002212.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718915701rs13233322CArs13233322208002211.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
718915874rs10486314AGrs10486314208002211.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
719036909rs7776735TCrs7776735208002215.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
719038332rs432AGrs432208002214.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
719042101rs10241753CTrs10241753208002212.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
719047369rs112954726TTCrs2717369208002217.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
719047369rs2717369TCrs2717369208002217.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
719059315rs9986679TArs9986679208002214.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
719190897rs12669145ACrs12669145208002214.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
719193626rs10257541ACrs10257541208002218.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
719197077rs1544371CTrs1544371208002218.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
721474580rs7795411GArs7795411200389472.01E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
721474664rs2282887CArs2282887200389478.32E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
721490045rs10233357CArs10233357200389476.35E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
721492171rs10950853TArs10950853200389478.19E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
721493866rs7793276ACrs7793276200389478.04E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
721496830rs12672607ATrs12672607200389471.50E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
721497574rs3807644CTrs3807644200389473.39E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
721504427rs17144465AGrs17144465200389478.00E-07NA1.56NA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionrs17144465-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
721504427rs17144465AGrs17144465201250886.00E-06NA1.82NA1,020 European cases; 1,636 European controlsEuropean(2656)ALL(2656)EUR(2656)ALL(2656)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs17144465-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
721506256rs10235984GTrs10235984200389473.60E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
721512722rs2282896GArs2282896200389474.76E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
721530104rs3807641AGrs3807641200389479.56E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
721539783rs12674215AGrs12674215200389472.13E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
721549853rs3823777GArs3823777200389476.75E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
722146840rs7793103AGrs7793103229077300.0001197NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
722324993rs1798806TCrs1798806208002219.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
724857983rs2106943ACrs2106943229077300.0001974NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
725480930rs2893208GCrs2893208231494480.0000354NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
726977192rs774257GArs774257198460678.25E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
726990816rs774246AGrs774246198460678.14E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
727388903rs17429065AGrs17429065216212693.11E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
727709673rs13237776CTrs13237776230914230.00000132NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
727709673rs13237776CTrs13237776230914230.00000177NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Norepinephrine reuptake inhibitors (NRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
727710555rs12534474GArs12534474230914230.00000132NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
727710555rs12534474GArs12534474230914230.00000177NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Norepinephrine reuptake inhibitors (NRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
728812493rs10238623AGrs10238623240474465.00E-06(Dichotomous)1.55NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs10238623-A
728842067rs2237364AGrs2237364213168607.74E-06Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGCREB5
731155347rs1558477TCrs1558477190651441.00E-06Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
731155347rs1558477TCrs1558477216212693.00E-07NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
731155347rs1558477TCrs1558477pha0028502.58E-06phs0000201.26NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNANANA
731157479rs7791986CGrs7791986190651442.60E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
731157479rs7791986CGrs7791986216212691.04E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
731157479rs7791986CGrs7791986pha0028508.41E-05phs0000201.21NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNANANA
732447226rs430356GArs430356208002218.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
732866723rs2392147TGrs2392147220599354.78E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
732921831rs6462430GArs6462430220599353.17E-04Sudden death suicides without a mood disorder vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
732921831rs6462430GArs6462430220599354.30E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
733847892rs4723335CTrs4723335220471842.75E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
733850385rs10244781TCrs10244781220471841.24E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
733852599rs11974796GTrs11974796220471847.20E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
735142669rs17205892TCrs17205892208002219.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
735145941rs66493729TGTCA,TTGrs6974100208002219.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
735145941rs6974100TCrs6974100208002219.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
735152038rs6978136TCrs6978136208002218.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
735669693rs2242031GArs2242031220471843.11E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
735684511rs4142249TCrs4142249220471842.75E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
735687137rs17766832GArs17766832220471842.79E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
735699350rs6945707ATrs6945707220471841.90E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
735704901rs9718654GArs9718654220471843.39E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
735707528rs17766868GArs17766868220471843.52E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
735729576rs17699327GArs17699327220471845.53E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
735729818rs17699339TCrs17699339220471846.83E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
736073873rs1882054TCrs1882054208002215.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736075385rs2700928CTrs2700928208002213.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736081175rs2718020ACrs2718020208002211.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736081436rs2718019ATrs2718019208002211.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736083679rs2710803CTrs2710803208002211.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736084923rs2718016GArs2718016208002211.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736090317rs2700942CArs2700942208002213.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736094146rs2710807CTrs2710807208002214.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736095950rs1882055AGrs1882055208002214.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736105035rs4292595CTrs4292595208002215.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736109747rs17263412CTrs17263412208002215.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736112365rs3735405GArs3735405208002215.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
736114716rs6962918GArs6962918208002215.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
738962722rs4723810CGrs4723810208002218.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
745982460rs2462686TCrs2462686233776409.00E-06partial response - SSRI treated - 2 weeks1.49[1.31-1.66] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs2462686-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
747441292rs12673398GTrs12673398206198268.50E-06Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: self-rated)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
747579031rs334504CGrs334504216212694.13E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGTNS3
749639378rs13244520GArs13244520210423172.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
749655966rs10239768CTrs10239768210423174.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
749662736rs4917070GArs4917070210423174.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
753496499rs17177762AGrs17177762200389478.00E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
753537843rs17692753GArs17692753200389474.97E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
753552890rs17620884GArs17620884200389477.33E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
753613811rs12718797GTrs12718797200389477.29E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
754551310rs472724TCrs472724224728763.94E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
768204103rs12534964GArs12534964224728767.57E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
768431641rs10499806GArs10499806208002214.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
768435475rs974468TArs974468208002212.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
768438751rs2008127TGrs2008127208002212.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
768442130rs2098183TArs2098183208002218.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
768446151rs4718837AGrs4718837208002214.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
768446862rs1485695CArs1485695208002212.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
768449516rs2904243AGrs2904243208002215.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
768454743rs12537001CTrs12537001208002215.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
768455493rs1485694CArs1485694208002215.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
769954583rs11760622TCrs11760622197363533.00E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
770161221rs11768039TGrs11768039210423172.70E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
770186936rs10279132TGrs10279132232901962.19E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
770473005rs1525293CTrs1525293233776402.00E-06remission - SSRI treated - 12 weeks1.7[1.48-1.92] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs1525293-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
770867166rs2960883AGrs2960883208002214.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
770916208rs11971260AGrs11971260208002212.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
770916290rs11974441GArs11974441208002217.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
770960437rs11977703GArs11977703208002215.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
770965242rs6970463CTrs6970463208002215.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
775380105rs11767756TGrs11767756220471843.85E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
777733273rs3807736ACrs3807736229077300.0000446NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
777733273rs3807736ACrs3807736229077300.0001146NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
777740606rs3807735GArs3807735229077300.0001318NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
777740625rs3807734GArs3807734229077300.0001318NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
777841529rs6976643TCrs6976643224728764.67E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
778043291rs17150687AGrs17150687220414583.00E-06Bupropion, SexNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers17150687-C
778256342rs38116CTrs38116191071154.90E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACMAGI2
778285960rs4730427CTrs4730427224728769.23E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
778322498rs12530747TCrs12530747224728762.67E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
778326526rs12536959CTrs12536959224728762.51E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
778353677rs10229438TCrs10229438224728765.62E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
778353733rs10229458TCrs10229458224728765.57E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
778354472rs10230190ATrs10230190224728765.62E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
778356377rs6953739TCrs6953739224728765.38E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
781499273rs12155338TArs12155338224728763.68E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
782396925rs17282875AGrs17282875190651444.30E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782396925rs17282875AGrs17282875190651447.50E-06Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782396925rs17282875AGrs17282875216212697.20E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGPCLO
782402373rs10954689CTrs10954689190651444.90E-05Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782402373rs10954689CTrs10954689190651449.10E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782417332rs6948464CTrs6948464190651445.50E-04Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782422405rs17156675CTrs17156675190651441.00E-04Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782422405rs17156675CTrs17156675190651441.10E-04Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782422405rs17156675CTrs17156675200389476.80E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782422937rs6979066GArs6979066190651442.70E-04Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782422937rs6979066GArs6979066190651448.10E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782422937rs6979066GArs6979066216212697.98E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGPCLO
782435878rs6954078GTrs6954078190651446.50E-07Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782435878rs6954078GTrs6954078190651448.80E-06Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782448100rs2522831TCrs2522831200389473.44E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782448405rs2715147CTrs2715147200389478.97E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782450035rs2715148ACrs2715148190651444.40E-07Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782450035rs2715148ACrs2715148190651448.40E-08Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782450035rs2715148ACrs2715148200389479.37E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782450035rs2715148ACrs2715148216212691.00E-06NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACPCLO
782450035rs2715148ACrs2715148pha0028501.46E-05phs0000201.23NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACPCLOUTR-3NM_014510
782450364rs2522832AGrs2522832200389473.15E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782451558rs1044639TGrs1044639200389476.37E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782453708rs2522833ACrs2522833190651446.40E-08Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782453708rs2522833ACrs2522833190651447.40E-07Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782453708rs2522833ACrs2522833200389476.44E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782453708rs2522833ACrs2522833216212692.46E-06NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAPCLO
782453708rs2522833ACrs2522833232901961.20E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
782453708rs2522833ACrs2522833pha0028501.54E-05phs0000201.23NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAPCLOmissenseNM_014510
782454404rs2247523CGrs2247523200389473.00E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782454672rs2371214TCrs2371214200389472.70E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782455895rs2715150AGrs2715150200389477.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782457666rs2715152GArs2715152200389478.78E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA,G
782462054rs2715155AGrs2715155200389477.59E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782462834rs2715156GArs2715156200389477.64E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782468184rs2257207ATrs2257207200389477.82E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782468374rs2715157AC,G,Trs2715157200389478.81E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782469606rs2715158GCrs2715158200389477.88E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782475557rs2522838TArs2522838200389477.91E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782477648rs2522839AGrs2522839200389477.85E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782478415rs2522840TGrs2522840190651441.60E-06Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782478415rs2522840TGrs2522840190651449.90E-07Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782478415rs2522840TGrs2522840200389479.60E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782478415rs2522840TGrs2522840216212694.38E-06NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGPCLO
782478415rs2522840TGrs2522840pha0028502.85E-05phs0000201.23NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGPCLOintronNM_014510
782479194rs2522841GTrs2522841200389477.85E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782480092rs2522844CTrs2522844200389477.72E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782501290rs2888018TGrs2888018190651441.50E-04Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782501290rs2888018TGrs2888018190651444.50E-05Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782555669rs2107828ATrs2107828190651442.80E-06Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782555669rs2107828ATrs2107828190651444.20E-06Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782555669rs2107828ATrs2107828216212691.48E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATPCLO
782555669rs2107828ATrs2107828pha0028505.11E-05phs0000201.22NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATPCLOintronNM_014510
782563516rs7799260CGrs7799260190651441.70E-05Recurrent early onset major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782563516rs7799260CGrs7799260190651442.80E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782563516rs7799260CGrs7799260216212699.70E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGPCLO
782573098rs12669254TCrs12669254208002212.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
782720226rs2057899CTrs2057899200389472.77E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782721742rs11562069AGrs11562069200389472.86E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782721814rs6955217TCrs6955217200389473.11E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782724539rs12531615TCrs12531615200389475.92E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782725319rs975727GArs975727200389474.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782725618rs6947662GCrs6947662200389474.24E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782727063rs2023984CTrs2023984200389474.46E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782728378rs6467929AGrs6467929200389474.46E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782729409rs17157155CTrs17157155200389472.87E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782730446rs12666717AGrs12666717200389473.04E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782730622rs10954706AGrs10954706200389474.48E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782730637rs10954707CTrs10954707200389474.50E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782730731rs7781169CTrs7781169200389474.50E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
782732583rs17819684GTrs17819684200389473.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782734006rs2190044AGrs2190044200389474.52E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782734845rs7791742TCrs7791742200389474.55E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782735376rs17157173GArs17157173200389474.75E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782735618rs17157177CTrs17157177200389472.67E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782735658rs16887406AGrs16887406200389473.57E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
782736474rs6950924CTrs6950924200389477.24E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
782736869rs6467931GArs6467931200389478.70E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
782779790rs4644166AGrs4644166224728765.87E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
783999393rs1228861CA,Grs1228861208002218.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784017279rs1228877CGrs1228877208002214.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784022766rs622514ACrs622514208002214.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784031430rs2158168TCrs2158168208002214.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784041080rs1634611TArs1634611208002214.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784046286rs1228957GArs1228957208002214.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784056502rs1228893ACrs1228893208002214.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784065937rs1228946GArs1228946208002219.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784071654rs2706910GCrs2706910208002215.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784076213rs2527530TCrs2527530208002219.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784082878rs1228964ATrs1228964208002214.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784086868rs1228967GArs1228967208002214.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784101085rs1228907GArs1228907208002214.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784102251rs1228908CGrs1228908208002214.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784103544rs1228969TGrs1228969208002214.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784105914rs1228974GArs1228974208002214.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784110281rs1228911TArs1228911208002214.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784115236rs1228932TCrs1228932208002213.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784126147rs1235296GArs1235296208002214.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784127398rs1029538TCrs1029538208002213.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784130829rs1228914GTrs1228914208002215.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784133847rs1228921ATrs1228921208002215.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784136126rs1228924CTrs1228924208002215.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784136556rs1228925AGrs1228925208002214.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784136907rs1228926CTrs1228926208002214.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784140810rs1228928CArs1228928208002213.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784142487rs1228968AGrs1228968208002213.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784145460rs1228897GArs1228897208002213.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784317206rs4278108GArs4278108208002213.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784318483rs4732577GArs4732577208002213.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784325487rs4481536CTrs4481536208002213.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784328077rs4329228ACrs4329228208002213.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784331306rs3924501CGrs3924501208002213.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
784692941rs2240394TCrs2240394217507021.52E-04Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTSEMA3D
784699387rs6966472TCrs6966472217507024.75E-05Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTSEMA3D
784956506rs2696171TGrs2696171208002219.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
787036105rs10487804GArs10487804224728765.21E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
787038074rs17149539AGrs17149539224728765.46E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
787041856rs11761050CArs11761050224728766.79E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
787043230rs17149547AGrs17149547224728766.79E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
787046470rs4148829AGrs4148829224728766.17E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
787047813rs7788404TCrs7788404224728767.42E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
787068464rs31674TCrs31674224728763.92E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
787069880rs31676TCrs31676224728764.36E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
790247308rs2106730TCrs2106730224728765.74E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
790800787rs2518782GTrs2518782208002215.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
794209932rs17400379TGrs17400379210423176.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
795173570rs12704800TCrs12704800210423176.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
795180018rs6953838GArs6953838210423178.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
795186726rs7810538TGrs7810538210423178.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
795210386rs6465471GArs6465471210423173.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
795210421rs6465472ATrs6465472210423174.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
795211643rs7811683TArs7811683210423177.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
795211716rs7793172GArs7793172210423173.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
795213702rs11531570GArs11531570210423173.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
798879348rs11972017TCrs11972017216212694.13E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACMYH16
798880642rs6960805CTrs6960805229077300.0001606NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
799435896rs496000GArs496000220471849.79E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC,T
7100266081rs221786TCrs221786220471847.42E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
7100285974rs221797ACrs221797220471845.92E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
7100313420rs506597AGrs506597220471846.00E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
7100321138rs564449TGrs564449220471841.23E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
7101115994rs17135437CTrs17135437227605533.00E-06AA - VisionhearingNANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression casesNOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs17135437-A
7101115994rs17135437CTrs17135437227605533.00E-08EA + AA - VisionhearingNANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs17135437-A
7101269515rs7799319AGrs7799319245282841.22E-06(S-CT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
7101269939rs4727504AGrs4727504245282841.28E-06(S-CT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
7101270780rs4727506AGrs4727506245282841.22E-06(S-CT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
7101272926rs848645TCrs848645245282841.24E-06(S-CT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
7101274653rs848648AGrs848648245282841.15E-06(S-CT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
7101284857rs1619382CTrs1619382245282841.07E-07(S-CT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralT
7101286177rs1722229GTrs1722229245282841.00E-06(S-CT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralT
7101809851rs365836AGrs365836225844592.00E-06NA4.79[2.38-9.64] 92 Japanese ancestry casesJapanese(92)ALL(92)ASN(92)ALL(92)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abusers365836-AResearch Support, Non-U.S. Gov't
7103125585rs7808106TCrs7808106224728769.66E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7103130403rs736707AGrs736707224728763.46E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7103141147rs13232021AGrs13232021224728768.07E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7103141437rs13235135AGrs13235135224728769.15E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7103141703rs17152161TCrs17152161224728767.71E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7104291453rs1468864TArs1468864198460676.77E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tALHFPL3
7105670992rs105347TCrs105347197363538.80E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
7106489003rs10487287GTrs10487287200389476.19E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
7109217355rs1524271CTrs1524271224728762.43E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7110920180rs37747CGrs37747237266685.00E-04NA2.04[1.45-2.86]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7112005565rs2708600CArs2708600208002218.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112016581rs10435366TCrs10435366220471844.30E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
7112036947rs2708593CTrs2708593208002219.73E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112038730rs991632GArs991632220471846.06E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
7112040361rs2523036GCrs2523036208002218.28E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112044527rs2520480CTrs2520480208002218.31E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112047345rs2520479TCrs2520479208002217.57E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112050437rs1557698AGrs1557698208002217.60E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112062186rs2520484TCrs2520484208002214.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112062274rs2520483GCrs2520483208002215.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112063748rs2708599AGrs2708599208002214.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112064238rs2520481TCrs2520481208002215.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112064376rs9640740GArs9640740220471843.34E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
7112068101rs728273GCrs728273208002219.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7112908788rs6466440TCrs6466440229077300.0001247NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7112908788rs6466440TCrs6466440229077300.0001898NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7112922865rs6962650TCrs6962650229077300.0000988NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7112922865rs6962650TCrs6962650229077300.0001873NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7113438644rs2023692GArs2023692229153520.0000038NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tTNA
7114663162rs17585678GCrs17585678208002219.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7114672720rs7791565AGrs7791565208002219.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7114682603rs1978097GTrs1978097208002212.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7114736232rs2460485TCrs2460485208002217.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7114750436rs12706009CTrs12706009208002219.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116043100rs10252986GArs10252986208002214.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116044566rs1918923AGrs1918923208002214.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116044688rs1918924GTrs1918924208002214.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116047011rs10247635GC,Trs10247635208002213.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116047190rs10247800GArs10247800208002215.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116057028rs10237417AGrs10237417208002214.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116063402rs6952334AGrs6952334208002214.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116067175rs10228039GArs10228039208002214.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116067291rs10227962CA,Grs10227962208002214.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116072835rs6963408AGrs6963408208002214.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116073292rs10282315AGrs10282315208002214.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116079236rs6466577GArs6466577208002214.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7116095006rs9656238AGrs9656238208002214.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7117536046rs12667152GTrs12667152232901962.88E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7117536700rs11977246TCrs11977246232901963.10E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7117544391rs17488749GArs17488749232901968.16E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7117544428rs17488784TArs17488784232901968.28E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7117579363rs16870152TCrs16870152232901962.46E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7123759980rs6466890AGrs6466890220471849.25E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
7123761909rs12538016CGrs12538016220471849.99E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
7125414227rs4731264AGrs4731264208002218.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7125414439rs739739AGrs739739208002218.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7126484050rs1419492CTrs1419492220471844.64E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
7126484315rs1361988GArs1361988220471846.34E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
7126490357rs13242233CTrs13242233220471848.17E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
7126496513rs2283079AGrs2283079220471847.15E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
7126631568rs17867725TCrs17867725208002214.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7126639604rs17864092TCrs17864092208002216.00E-06NA0.17[NA] unit decrease3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs17864092-TMeta-AnalysisResearch Support, N.I.H., Intramural
7126639604rs17864092TCrs17864092232901965.50E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7129218091rs6961403GArs6961403210423173.80E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7129244793rs6942490CTrs6942490210423175.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7129252853rs753947GArs753947210423174.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7129310092rs7797729TCrs7797729210423172.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7129380243rs7796553TCrs7796553210423172.30E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7129380421rs7777812CTrs7777812210423172.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7129799845rs10241132GArs10241132213168604.84E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
7129842229rs17164729TCrs17164729213168601.82E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATTMEM209
7130386523rs6964185AGrs6964185232901965.53E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7130884163rs6978508ACrs6978508200389479.83E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7130888500rs17165484AGrs17165484200389479.82E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
7130897144rs1565051GCrs1565051200389473.19E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
7130900121rs10265216TArs10265216200389473.00E-06NA1.19NA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionrs10265216-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
7130901642rs7811386CGrs7811386200389478.80E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7130903178rs1979567TCrs1979567200389471.62E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
7131363452rs11764710GArs11764710216212693.81E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
7131385220rs10231383GArs10231383191071157.01E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
7131505116rs1122732TGrs1122732229077300.0002104NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
7131750195rs10954355CTrs10954355200389471.56E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC,T
7131750471rs10248132CTrs10248132200389472.18E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7131761018rs4731841GTrs4731841200389473.25E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
7131762179rs4731843AGrs4731843200389479.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
7131763974rs4731844CTrs4731844200389473.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
7131766198rs4731845CTrs4731845200389472.81E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7131767043rs9649571TCrs9649571200389472.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
7131768074rs12707024GArs12707024200389472.91E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
7131768282rs1514051CTrs1514051200389472.91E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
7132386086rs523343TGrs523343210423179.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7132386513rs527159ATrs527159210423171.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7132389459rs541186GCrs541186210423178.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7132409194rs580068CArs580068210423172.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7134972126rs10954491CTrs10954491200389472.81E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7134972126rs10954491CTrs10954491216212697.57E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
7136984716rs16874937CTrs16874937208002216.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
7137858766rs10255295AGrs10255295224728763.02E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7139672617rs10260531GTrs10260531224728763.21E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7139976963rs6948262CTrs6948262229077300.000091NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7142554278rs7779406GArs7779406210423172.20E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7142554845rs8177113CA,Grs8177113210423172.00E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7143682946rs10226688GTrs10226688229077300.0001838NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
7144112357rs929289GArs929289191071159.38E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
7144134651rs9648813CTrs9648813191071152.84E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
7144783523rs9640436CTrs9640436231494480.0000392NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7146600338rs10081247GCrs10081247224728762.00E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7146652162rs12703863TCrs12703863224728761.25E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7146663568rs940455GTrs940455224728761.76E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7146668551rs12703869GTrs12703869224728762.34E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7146942272rs1496545GArs1496545200389477.44E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA,G
7147594096rs7778252CTrs7778252231494480.0000226NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
7148914122rs1202390GArs1202390216212699.84E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGZNF282
7149450663rs12674335AGrs12674335191071158.13E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
7151094048rs11761588TCrs11761588229077300.0001089NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
7153607630rs10487688TCrs10487688198460676.71E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
7156880398rs6966038AGrs6966038198460674.00E-07remission1.68[1.37-2.04] Up to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
7156880398rs6966038AGrs6966038198460675.00E-07response1.64[1.35-1.99] Up to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
81680901rs11990748ACrs11990748208002216.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
83522251rs12542057TCrs12542057208002212.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
83526097rs7822379GArs7822379208002212.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
83529525rs7815362GArs7815362208002212.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
83848750rs940155AGrs940155216212694.22E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATCSMD1
83936904rs2554635CGrs2554635224728764.38E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
83937595rs1971078AGrs1971078224728764.54E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
84467334rs2725045GTrs2725045210423172.00E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
84467853rs2725046AGrs2725046210423179.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
84469330rs1564179GArs1564179200389477.56E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
84469330rs1564179GArs1564179210423177.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
85461936rs4875599CTrs4875599208002217.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85494638rs12680594AGrs12680594216212696.68E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
85533942rs17362595AGrs17362595208002211.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85541910rs17362797TCrs17362797208002211.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85543809rs11774578TCrs11774578208002217.42E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85544223rs7015554AGrs7015554208002217.90E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85544991rs7817815TCrs7817815208002217.84E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85545069rs7814262AGrs7814262208002217.84E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85545090rs7831044CArs7831044208002217.84E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85546824rs17362923CGrs17362923208002218.59E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85548229rs10503333ATrs10503333208002216.86E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85549619rs17453815AGrs17453815208002212.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85551013rs4875612AGrs4875612208002212.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85551530rs7006473TCrs7006473208002216.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85551845rs6982207GArs6982207208002211.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85552197rs17363043TArs17363043208002213.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85552794rs17453899GArs17453899208002212.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85552825rs17453906GCrs17453906208002211.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85552851rs17363064GArs17363064208002211.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85553067rs7819155GCrs7819155208002213.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85553276rs10448113GCrs10448113208002212.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85553797rs10866995TArs10866995208002212.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85554098rs11774958CArs11774958208002215.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85554323rs11778521AGrs11778521208002217.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85576744rs263332TCrs263332208002217.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
85676058rs10092548AGrs10092548240474463.24E-05(Quantitative)0.45[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs10092548-A
89046312rs1968853ACrs1968853208002211.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
89065964rs17149522CGrs17149522208002211.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
89073921rs2929287ATrs2929287208002215.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
89085355rs7841403GArs7841403208002212.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
89086451rs10108415CArs10108415208002214.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
89088280rs330053GTrs330053208002215.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
89091739rs6601296GArs6601296208002213.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
89372305rs10090821CGrs10090821208002217.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
89373545rs7839849CTrs7839849208002217.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
810210451rs6997710AGrs6997710208002214.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
812593429rs11781870CTrs11781870216212697.32E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACLONRF1
812824893rs2203834ACrs2203834229077300.0001157NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
812824893rs2203834ACrs2203834229077300.0001214NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
813470249rs7838784TCrs7838784197363539.70E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
814668859rs7002469AGrs7002469229153520.00000167NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset>25HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tASGCZ
815666113rs6989226GCrs6989226205161561.81E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
815666113rs6989226GCrs6989226224728765.84E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
815666800rs2049833AGrs2049833205161563.42E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyT
816929635rs10090288ACrs10090288220641628.00E-06NA2.55[1.69-3.84] 467 European ancestry cases; 407 European ancestry controlsEuropean(874)ALL(874)EUR(874)ALL(874)Depression and alcohol dependenceHPOID:0000716DepressionDOID:303DOID:1596substance-related disordermental depressionD003863DepressionNANADepressionDrug abuseNA
818044101rs7818834TCrs7818834216212695.87E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNAT1
818121307rs6586730AGrs6586730208002216.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
818169778rs11782404ATrs11782404208002219.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
818469396rs1487760ACrs1487760208002219.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
819377781rs2975468TCrs2975468224728762.96E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
819379676rs4922053GArs4922053224728761.63E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
819380311rs6992386CTrs6992386224728763.00E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
819382331rs2975494AGrs2975494224728761.53E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
819389899rs10503652GArs10503652224728761.86E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
819539638rs7816924CTrs7816924237266682.00E-07NA2.14[1.53-2.99]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionrs7816924-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
820058757rs6586899TGrs6586899200389472.47E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
820063137rs2410638GTrs2410638200389472.03E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
820064771rs4335136TCrs4335136200389473.20E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
820066049rs1106634GArs1106634200389477.00E-07NA1.3NA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionrs1106634-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
820066618rs11778205AGrs11778205200389473.35E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
820069789rs10156354GCrs10156354200389479.38E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
820071770rs13253777CGrs13253777200389475.74E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
820081890rs1390943TGrs1390943200389473.69E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
820088118rs10095373TGrs10095373200389472.22E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
820088733rs974994TCrs974994200389472.10E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
823201103rs7013955GArs7013955220471846.98E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
824677490rs1016446AGrs1016446200389479.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
824769852rs1457266AGrs1457266190651442.90E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
824769852rs1457266AGrs1457266pha0028504.27E-05phs0000201.23NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNEFMnearGene-5NM_005382
826575680rs6994883AGrs6994883216212695.70E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
826576125rs11779314CTrs11779314216212693.25E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
827171486rs7833348TCrs7833348pha0028507.55E-05phs0000201.63NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACPTK2BintronNM_173174
827263433rs7000615GTrs7000615216212693.80E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATPTK2B
827362142rs7846038TCrs7846038197363531.20E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
830867266rs2725376GCrs2725376216212698.95E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACPURG
834126948rs6990255CTrs6990255224728768.12E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
834236992rs2609653CTrs2609653224728768.92E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
839993166rs7825010AGrs7825010232901966.74E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840003790rs10091355TCrs10091355232901961.16E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840004060rs10101533GArs10101533232901961.77E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840004160rs10101647GArs10101647232901968.51E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840007469rs7833452AGrs7833452232901962.27E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840010253rs1383605TArs1383605232901961.88E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840010710rs7004479CTrs7004479232901961.87E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840010820rs2242277TCrs2242277232901962.28E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840013811rs10958604GTrs10958604232901966.88E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840014026rs12679544CTrs12679544232901962.80E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840016464rs11784532CTrs11784532232901968.58E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840019174rs12541821GArs12541821232901967.51E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840020831rs7822661CTrs7822661232901968.66E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
840807189rs4736893AGrs4736893232901969.91E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
853935694rs1426562AGrs1426562216212693.01E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
853935694rs1426562AGrs1426562pha0028503.34E-05phs0000201.28NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
853939511rs6473783CTrs6473783216212694.14E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
853939511rs6473783CTrs6473783pha0028505.28E-05phs0000201.27NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNANANA
856116482rs11783005CTrs11783005232901967.79E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
856119840rs13250310ATrs13250310232901964.99E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
856120404rs13248919GArs13248919232901968.92E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
857982790rs4541915CTrs4541915220471848.95E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
858628032rs7836900GArs7836900206198267.10E-06Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: Depressed Affect Factor Score)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
859599500rs4738700TCrs4738700232901967.98E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
861804729rs13251621CTrs13251621229077300.0002521NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
861998100rs11987923AGrs11987923220471845.89E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
863790083rs4439119GTrs4439119229077300.0001981NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
863808400rs1869733CTrs1869733229077300.0000219NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
863812686rs1455583GTrs1455583229077300.0000406NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
863822440rs1455576AGrs1455576229077300.0001862NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
869042668rs1434756TGrs1434756197363532.10E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
870871068rs389540AGrs389540229153520.0000095NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tANA
873053079rs10504532GArs10504532216212697.16E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
874499435rs13277065TCrs13277065224728765.61E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
881500656rs7005189CTrs7005189190651442.80E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
881500656rs7005189CTrs7005189216212691.81E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
881500656rs7005189CTrs7005189pha0028504.15E-05phs0000201.32NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNANANA
881839692rs1445570GArs1445570224728769.50E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
883903814rs7015622AGrs7015622220414581.00E-06Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers7015622-C
886547351rs987390GArs987390205161561.58E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyG
886547351rs987390GArs987390229153520.000000147NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<35HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNA
886547351rs987390GArs987390229153520.00000312NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<30HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNA
886547351rs987390GArs987390229153520.0000038NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<25HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNA
886849171rs2930553GTrs2930553205161562.48E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
890795768rs10097279GArs10097279216212697.47E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAG,ARIPK2
893597541rs1449249CTrs1449249200389478.91E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
893600470rs1463186TCrs1463186200389478.23E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
896784526rs12676394CArs12676394229077300.000209NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
896835380rs568815ACrs568815210423171.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
898367001rs7833199TCrs7833199200389474.46E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
898367884rs4735451CTrs4735451200389477.22E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
898368210rs4735454CTrs4735454200389477.76E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
898370806rs11780372CTrs11780372200389479.50E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
898371242rs7834781ATrs7834781200389479.63E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
898373598rs4735457ACrs4735457200389475.37E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
898374249rs6468552GTrs6468552200389476.16E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
898374866rs4734360CGrs4734360200389477.69E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
898375057rs4735458ATrs4735458200389477.78E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
898377549rs6468553ACrs6468553200389478.67E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
898385871rs10808355GTrs10808355200389478.96E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
898626459rs2448148TCrs2448148208002216.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898627865rs2512429TArs2512429208002217.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898631311rs2512431AGrs2512431208002216.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898632764rs2512433AGrs2512433208002216.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898634070rs2512434TGrs2512434208002216.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898634789rs2512435TCrs2512435208002216.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898635877rs2512436CTrs2512436208002216.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898635943rs2512437AGrs2512437208002216.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898636391rs2512438ATrs2512438208002216.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898637212rs2438228GArs2438228208002216.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898637731rs2448145CArs2448145208002216.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898640579rs1013412CTrs1013412208002216.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898641733rs2438226TCrs2438226208002214.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
898953076rs2085144GArs2085144229077300.0000609NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
898953076rs2085144GArs2085144229077300.0002123NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
8101085056rs2446930CTrs2446930224728767.40E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8101484612rs881491GCrs881491200389475.02E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8101484638rs881492CGrs881492200389474.54E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8101485007rs881485ACrs881485200389477.57E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
8101488120rs2844044GCrs2844044200389479.57E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8101488821rs2844043ACrs2844043200389471.96E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
8101492039rs2154636CTrs2154636200389477.47E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8101692130rs1786330CTrs1786330200389472.96E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8101702119rs11785473TArs11785473200389472.08E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
8101709538rs1693543CTrs1693543200389472.53E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8101712153rs1786322ACrs1786322200389472.53E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8102654182rs2226399TCrs2226399229077300.000179NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8103044961rs6987078GArs6987078210423177.30E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8103356112rs10481053ACrs10481053224728763.87E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8106606008rs7015353AGrs7015353200389472.97E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8106618662rs12679854GArs12679854200389471.39E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8106618733rs7015025GArs7015025200389471.39E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8106619255rs6981187AGrs6981187200389471.39E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8106621481rs1450168CGrs1450168200389477.72E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8106621925rs9785073GArs9785073200389471.33E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8106627197rs1037304AGrs1037304200389471.27E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8106635651rs1901064GArs1901064200389473.11E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8107163978rs1366963CArs1366963197363539.60E-07Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
8110090458rs3110052CTrs3110052220471844.50E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
8110101775rs3134106GTrs3134106220471849.84E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
8110103867rs3134107GArs3134107220471844.49E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
8110106120rs3110045CTrs3110045220471845.37E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
8116020787rs4433181AGrs4433181231494480.000012NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8116633699rs2721937CTrs2721937224728768.00E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8118734726rs3105764TArs3105764pha0028505.46E-05phs0000201.22NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
8118820371rs17429936TGrs17429936208002211.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118820442rs28357253ATrs28357253208002212.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118898839rs17475190ACrs17475190208002219.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118901452rs13252084CTrs13252084208002219.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118901524rs4621831TCrs4621831208002219.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118901585rs4480148AGrs4480148208002218.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118910911rs7822297GArs7822297208002219.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118911796rs10106675CTrs10106675208002218.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118916104rs28357275GArs28357275208002219.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118916467rs28357277TGrs28357277208002219.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118916779rs17453043CTrs17453043208002219.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118917627rs4391466TCrs4391466208002218.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118917677rs5005135AGrs5005135208002218.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118918885rs17430610CGrs17430610208002216.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118922172rs7824395AGrs7824395208002218.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118922226rs7842917TCrs7842917208002217.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8118922698rs7843515TCrs7843515208002218.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8121332791rs6469916GArs6469916220599352.96E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8122586618rs16895672TGrs16895672208002217.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8122587966rs7009299CTrs7009299208002218.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8122589015rs16895680CTrs16895680208002218.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8123536380rs4636213GArs4636213232901962.59E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8123539936rs10505424CArs10505424232901963.24E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8123545374rs16893023CArs16893023232901963.80E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8124548436rs4436105GArs4436105229077300.0001131NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8124548436rs4436105GArs4436105229077300.0001801NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8124566356rs6996389TCrs6996389229077300.000225NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
8124580116rs7816339GTrs7816339229077300.0001764NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
8124586305rs2385296ACrs2385296229077300.0000342NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
8124689847rs4870864ACrs4870864224728766.38E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8125238368rs4242365AGrs4242365229077300.000059NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8125243975rs7015300GArs7015300208002212.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8125246795rs6989030CTrs6989030208002211.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8125246937rs6993070CTrs6993070208002212.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8125284359rs4457311GArs4457311229077300.0001438NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
8126287888rs7845165GArs7845165208002218.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8126474306rs2980885GArs2980885191071157.29E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
8126481694rs2980876CTrs2980876191071155.12E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
8126481952rs2954020AGrs2954020191071155.12E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
8126485531rs7846466TCrs7846466191071151.46E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
8127836007rs6983330AGrs6983330208002219.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8127836137rs7003931TCrs7003931208002219.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8127838101rs6994585GArs6994585208002219.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8127838809rs13270320GArs13270320208002219.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8127839267rs16901732TCrs16901732208002219.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8127839603rs16901733GCrs16901733208002219.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8127839806rs13279644CTrs13279644208002219.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8128295710rs412835CArs412835220471846.03E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
8128302639rs17378569CTrs17378569220471845.25E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
8128303372rs12216777CTrs12216777220471846.24E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC,T
8128504497rs17766217TCrs17766217220414583.00E-07Citalopram+Buspirone, General SENANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers17766217-A
8130788548rs4733741CTrs4733741210423179.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8131031801rs750677CGrs750677208002218.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8131033928rs4733566GTrs4733566208002216.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8131034911rs7463674ATrs7463674208002216.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8131038848rs6470790AGrs6470790208002215.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8131039109rs6470791TCrs6470791208002216.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8133471941rs2597348CTrs2597348220471841.63E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
8133472362rs2403775AGrs2403775220471841.86E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
8134030488rs869769TCrs869769208002214.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8137313038rs1492970TArs1492970220471842.06E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
8137319350rs923791TGrs923791220471848.19E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
8137330446rs7820587CTrs7820587220471848.47E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
8137337480rs923792TCrs923792220471848.66E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
8137995401rs1499449TCrs1499449210423176.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8137997343rs11166680CGrs11166680210423178.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8138008250rs7014243TArs7014243210423176.40E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8138024322rs6995856TCrs6995856210423176.50E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8138076583rs11989063CGrs11989063210423172.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8138097930rs4256627TCrs4256627210423175.40E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8138506934rs1849692TCrs1849692229077300.0002012NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
8138522685rs16907427CTrs16907427229077300.0001743NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
8138522685rs16907427CTrs16907427229077300.0002012NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
8138602460rs12541822TArs12541822224728764.26E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8139298819rs10505698AGrs10505698208002212.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139634852rs4576426TGrs4576426197363532.80E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
8139647262rs10091563AGrs10091563208002215.57E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139658747rs4909439CTrs4909439208002211.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139659232rs6577938TGrs6577938208002212.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139659737rs4909440TCrs4909440208002212.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139660353rs6982714GTrs6982714208002211.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139660425rs6984002CGrs6984002208002212.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139660473rs6982882GCrs6982882208002212.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139661487rs6988358GCrs6988358208002211.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139662751rs6577939CG,Trs6577939208002217.64E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139663617rs3923549AGrs3923549208002213.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139664484rs3924863GArs3924863208002217.25E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139664516rs3924862GArs3924862208002217.29E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139665734rs6985495GCrs6985495208002219.30E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139665846rs4073447ATrs4073447208002218.46E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139665874rs4073446AGrs4073446208002218.48E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139668786rs6421014GArs6421014208002218.81E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139669063rs7002247GTrs7002247208002213.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139669119rs6989017TCrs6989017208002211.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139669569rs7460303AGrs7460303208002216.06E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139672167rs4072881CTrs4072881208002216.40E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139672602rs4072506TCrs4072506208002216.43E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
8139888196rs12549200GArs12549200210423174.20E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8140602616rs2542436TCrs2542436197363533.30E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
8141210214rs13259162GArs13259162213168606.65E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGTRAPPC9
9590454rs2642006TCrs2642006197363534.50E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
9955794rs364477CTrs364477233776404.00E-06remission - SSRI treated - 12 weeks1.69[1.47-1.92] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs364477-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
92194227rs4741652CTrs4741652224728761.06E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
93866849rs6476722GArs6476722224728762.88E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
94991840rs2890618TCrs2890618208002215.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
94993082rs1327493CGrs1327493208002215.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
94993267rs6476934TGrs6476934208002214.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
97387977rs10511468ACrs10511468210423174.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
97388656rs4742341AGrs4742341210423177.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
97389700rs6477194GCrs6477194210423176.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
97397527rs10815607CTrs10815607210423173.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
97480472rs2986278TGrs2986278210423171.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
97482618rs3955044AGrs3955044210423173.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
97485343rs10815615AGrs10815615210423176.30E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
97685999rs328844AGrs328844208002217.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
97692837rs328843GCrs328843208002212.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
97694484rs842301TCrs842301208002218.79E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
99149546rs10977530GArs10977530216212698.15E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGPTPRD
99229743rs12380021CGrs12380021216212696.16E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGPTPRD
99504580rs11790706TGrs11790706224728766.21E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
910192290rs294856ACrs294856240474462.00E-06NA1.34NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
911911621rs13297301ATrs13297301208002218.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
912265588rs10960554TCrs10960554208002217.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
914065522rs564854CArs564854197363531.80E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
914087769rs7858CTrs7858197363531.00E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
914547633rs12002454TCrs12002454213168609.36E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATNA
914610866rs1343705GArs1343705229077300.0001925NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
914633299rs4620377TCrs4620377229077300.0000489NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
914633299rs4620377TCrs4620377229077300.0001717NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
916282340rs1332479CTrs1332479208002218.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
916286344rs10962365GArs10962365208002216.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
916286587rs10962366TCrs10962366208002216.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
916286870rs10810544CTrs10810544208002215.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
916288875rs1114539GArs1114539208002216.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
916289910rs7850784GArs7850784208002214.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
916290697rs7861593AGrs7861593208002214.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
916299425rs10810549GArs10810549208002214.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
917630500rs4504735CTrs4504735208002211.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
918300883rs10963561AGrs10963561210423171.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
918574806rs10756976ACrs10756976197363532.20E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
918776840rs1549986ACrs1549986210423172.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
919781086rs10964284CTrs10964284224728761.03E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
921150650rs7855438CArs7855438208002219.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
922098574rs4977574AGrs4977574233776401.36E-08NANANAUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922124477rs10757278AGrs10757278233776408.73E-10NANANAUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922125503rs1333049GCrs1333049233776404.43E-09NANANAUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
923072095rs2383253AGrs2383253216212692.05E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
923728372rs10811962AGrs10811962231494480.0000295NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
923887854rs1376141AGrs1376141229153520.000013NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tANA
926226441rs2016672ACrs2016672200389473.35E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
926226927rs1434866CTrs1434866200389476.25E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
926359420rs2618000GTrs2618000208002219.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
926762105rs17693610CTrs17693610208002213.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
926771916rs16910779ACrs16910779208002219.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
928463701rs7044907GArs7044907229077300.0001855NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
929336303rs16914695AGrs16914695213168601.50E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
929504458rs10969210CTrs10969210213168601.96E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
930119722rs10969562TArs10969562208002217.35E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930119796rs1510911ACrs1510911208002212.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930119908rs4878423CTrs4878423208002211.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930122753rs1510910CArs1510910208002212.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930122786rs1510909CTrs1510909208002218.05E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930125557rs7875798TCrs7875798208002211.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930128393rs7030976TCrs7030976208002219.82E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930130067rs9919065ATrs9919065208002212.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930130213rs9918985GTrs9918985208002211.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930137451rs1606053TCrs1606053208002218.21E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930143230rs1018254CTrs1018254208002211.87E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
930982002rs7038348CTrs7038348224728764.73E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
930982620rs7024630TCrs7024630224728764.14E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
931027597rs10757999GArs10757999224728765.90E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
931165966rs12553567ATrs12553567231494480.0000555NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
933092835rs10813942ACrs10813942229077300.0002074NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
936723143rs10973041CTrs10973041210423175.00E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
937331605rs12378217TGrs12378217216212692.76E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATZCCHC7
937331605rs12378217TGrs12378217pha0028505.00E-05phs0000201.3NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATZCCHC7intronNM_032226
937693006rs3827513TCrs3827513191071159.11E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATFRMPD1
937693006rs576020823TACACTrs3827513191071159.11E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATFRMPD1
937719011rs2013458TCrs2013458191071157.50E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATFRMPD1
938639318rs12340088TGrs12340088230914230.00000497NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
973285588rs17460690TCrs17460690224728768.28E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
973915535rs1394309GArs1394309232901965.05E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
974836085rs11143176GTrs11143176224728761.25E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
974836247rs10869149TCrs10869149224728761.23E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
974845989rs10869150CArs10869150224728765.55E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
974846104rs17057536AGrs17057536224728764.85E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
974850932rs10869151ACrs10869151224728765.82E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
974851035rs11143186AGrs11143186224728761.06E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
976316341rs11143665AGrs11143665206198263.80E-08Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: Depressed Affect Factor Score)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
976316341rs11143665AGrs11143665206198265.60E-07Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: self-rated)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
976337403rs11143678TGrs11143678206198261.90E-07Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: Depressed Affect Factor Score)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
976337403rs11143678TGrs11143678206198262.70E-06Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: self-rated)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
976337514rs11143679CTrs11143679206198261.10E-07Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: Depressed Affect Factor Score)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
976337514rs11143679CTrs11143679206198261.60E-06Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: self-rated)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
976342406rs11143683TCrs11143683206198261.60E-07Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: Depressed Affect Factor Score)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
976342406rs11143683TCrs11143683206198262.60E-06Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: self-rated)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
978518999rs10869665CTrs10869665229077300.0002098NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
978518999rs10869665CTrs10869665229077300.0002215NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
979004213rs11144870CTrs11144870229077300.00000104NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
979004213rs11144870CTrs11144870229077300.00000104NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
979004213rs11144870CTrs11144870229077300.000037NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
979034262rs10116800TCrs10116800229077300.0001049NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
979065299rs11144905ACrs11144905229077300.00000143NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
979065299rs11144905ACrs11144905229077300.00000143NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
979065299rs11144905ACrs11144905229077300.000074NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
979101006rs785916AGrs785916229077300.0000075NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
979101006rs785916AGrs785916229077300.0000075NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
979101006rs785916AGrs785916229077300.00021NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
979126953rs680448AGrs680448229077300.0000564NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
979126953rs680448AGrs680448229077300.000163NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
980075134rs1547190CTrs1547190229077300.0001055NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
980226683rs3905108CTrs3905108224728761.77E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
980824321rs2026390GArs2026390220471844.13E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
980910643rs3808906TArs3808906220471845.50E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
982422832rs10512091AGrs10512091198460671.45E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNA
982422832rs10512091AGrs10512091206198267.80E-06Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: Depressed Affect Factor Score)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
982422832rs10512091AGrs10512091206198268.00E-06Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: self-rated)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
984419758rs669223TGrs669223208002214.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
985521271rs7026976AGrs7026976210423171.40E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
986177073rs4412434ATrs4412434224728764.41E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
987816616rs1931113AGrs1931113208002218.15E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987820596rs7850866AGrs7850866208002219.95E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987822415rs1931114ACrs1931114208002213.13E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987823068rs1571331AGrs1571331208002213.12E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987823812rs10156437AGrs10156437208002212.95E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987825118rs1889250CTrs1889250208002213.10E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987825889rs7045204GArs7045204208002212.85E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987827039rs10868266GArs10868266208002212.82E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987830448rs7859866ATrs7859866208002212.70E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987832469rs1931093AGrs1931093208002212.69E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987833517rs10868267CTrs10868267208002213.72E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987834342rs11140892CTrs11140892208002214.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987834508rs11140893TGrs11140893208002213.95E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987835091rs7030902GArs7030902208002219.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987837741rs10868268AGrs10868268208002212.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987843840rs4147134CTrs4147134208002213.83E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987844016rs11140900CTrs11140900208002213.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987844249rs11140901GArs11140901208002219.67E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987845035rs11140902CTrs11140902208002212.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987845670rs11140903GArs11140903208002219.01E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987847282rs2378682GArs2378682208002213.34E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987851625rs12379112CGrs12379112208002215.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987852583rs992303CTrs992303208002215.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987856534rs7039476TCrs7039476208002211.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987856663rs6559851GCrs6559851208002215.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
987857686rs1931097GCrs1931097208002215.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
993613106rs10993714ATrs10993714224728769.54E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
994246772rs4743837GArs4743837224728766.70E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
994321069rs2131301GTrs2131301224728767.58E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
994333599rs902923CTrs902923224728765.48E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
994373806rs9409623GArs9409623200389477.86E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
994376908rs9409443TArs9409443200389475.85E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
994378253rs7027715GArs7027715200389478.82E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
994870152rs1970121CArs1970121220599354.63E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
997403720rs4111369CTrs4111369200389475.37E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
998827814rs7867155CTrs7867155240474469.00E-07(Dichotomous)1.84NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
9100574120rs7870795TCrs7870795230914230.00000315NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9100575888rs7859751GArs7859751230914230.00000284NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9103068905rs4743392TA,Crs4743392210423172.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9103191461rs11790432AGrs11790432240474462.41E-05NA1.89NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs11790432-G
9104266953rs1929496ACrs1929496231494480.0000587NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9106854605rs10991104GArs10991104200389478.49E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
9111075125rs10979316ATrs10979316208002214.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111077062rs7033347TCrs7033347208002214.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111077461rs7033858TCrs7033858208002215.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111078622rs4978679TArs4978679208002214.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111079759rs1830704TCrs1830704208002214.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111080846rs13283083TGrs13283083208002216.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111081801rs10979317TCrs10979317208002216.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111082271rs4978345TGrs4978345208002215.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111083964rs1323387AGrs1323387208002215.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111084515rs1407854TCrs1407854208002216.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111085427rs1323388TCrs1323388208002215.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111085981rs7860612CTrs7860612208002215.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111086120rs7860923GTrs7860923208002216.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111086396rs942136AGrs942136208002215.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111092662rs4631545ATrs4631545208002217.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111092798rs10816659CTrs10816659208002217.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111094462rs6477632TCrs6477632208002217.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111094710rs6477634AGrs6477634208002217.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111094805rs6477635CGrs6477635208002215.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111095529rs7035490TArs7035490208002217.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111095847rs2417854GCrs2417854208002217.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111097895rs6477639GCrs6477639208002216.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111098115rs7031855GArs7031855208002216.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111098510rs1323389TCrs1323389208002216.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111099150rs7863237AGrs7863237208002216.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111100388rs1323391CTrs1323391208002216.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111102607rs1323393CTrs1323393208002216.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111103718rs1923966TGrs1923966208002217.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111103947rs1923967CGrs1923967208002218.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111105109rs1114278TCrs1114278208002216.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111106217rs12550936GTrs12550936208002216.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111106263rs7043512CGrs7043512208002217.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111107191rs1323396ACrs1323396208002214.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111107390rs7048064CTrs7048064208002214.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111108110rs4978685GArs4978685208002215.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111109673rs7045550TCrs7045550208002214.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111110747rs4978686TCrs4978686208002214.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111113479rs2417855GCrs2417855208002215.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111114348rs2146785CTrs2146785208002216.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111118529rs12551690CTrs12551690208002216.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111119332rs1535622TCrs1535622208002216.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111120353rs10979326ACrs10979326208002213.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111123697rs12379749TCrs12379749208002215.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111128578rs10979332TCrs10979332208002211.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111132382rs7018489CTrs7018489208002211.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9111135098rs7852356TArs7852356208002216.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9113486002rs4259484TCrs4259484208002219.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9113488684rs4332201TCrs4332201208002218.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9113834396rs1978302CGrs1978302208002217.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9115452656rs1711746AGrs1711746220471846.66E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
9115459708rs786977AGrs786977220471841.56E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
9115462594rs2185769AGrs2185769220471841.52E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
9115465282rs1418410AGrs1418410220471848.59E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
9115610148rs4979166TCrs4979166220471845.68E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
9115610429rs10759589GArs10759589220471846.66E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
9115611114rs912661TArs912661220471845.73E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
9115612797rs9299211GArs9299211220471845.77E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
9115612829rs9299212TGrs9299212220471845.77E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
9115613915rs10759592AGrs10759592220471845.76E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
9115614403rs10759593CTrs10759593220471845.75E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
9115614693rs4366151TCrs4366151220471845.74E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
9115614925rs10817397GArs10817397220471845.72E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
9115615025rs10759596CGrs10759596220471847.84E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
9115615241rs10733596TGrs10733596220471845.69E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
9115615580rs10759598TCrs10759598220471845.79E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
9115615754rs1970528AGrs1970528220471846.68E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
9115615955rs1539342AGrs1539342220471847.39E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
9115615985rs1970527GCrs1970527220471845.80E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
9115616152rs1539340CTrs1539340220471845.82E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
9115616388rs10817398TA,C,Grs10817398220471845.86E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
9115616408rs10759599CTrs10759599220471845.85E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
9115616434rs10817399CTrs10817399220471845.85E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT,C
9115616447rs10759600TCrs10759600220471845.85E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
9115635252rs7032763ATrs7032763220471843.98E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
9116782921rs10982035TCrs10982035208002218.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9116794037rs4574916GCrs4574916208002211.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9116794078rs752035CGrs752035208002214.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9116798141rs4979333AGrs4979333208002215.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9116800606rs10121424TCrs10121424208002215.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9116800860rs10124293AGrs10124293208002215.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119579003rs13287008TCrs13287008208002216.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119579244rs13285982AGrs13285982208002215.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119604993rs12335373CGrs12335373208002216.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119633124rs10817947GArs10817947208002218.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119638009rs4333683GArs4333683208002219.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119639424rs10817951CTrs10817951208002214.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119641530rs7868701CTrs7868701208002213.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119642094rs7042673GArs7042673208002212.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119645481rs12336175GArs12336175208002214.03E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119652497rs7035794CTrs7035794208002212.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119653328rs16934021GArs16934021208002214.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9119685232rs4838020GArs4838020208002213.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9120623523rs1828887CTrs1828887200389479.03E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
9120734599rs2225602AGrs2225602224728765.88E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9121604646rs2148473AGrs2148473232901966.39E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9121607349rs10984257TCrs10984257232901965.72E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9121636934rs10984272ATrs10984272232901966.57E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9121650692rs7467375GTrs7467375232901967.20E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9121651958rs10984285CTrs10984285232901966.61E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9123421879rs2274144AGrs2274144208002219.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9125245724rs10818702CTrs10818702230914230.00000219NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9127001421rs7861578CTrs7861578216212698.89E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
9127195873rs10986339GArs10986339200389474.53E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
9127195873rs10986339GArs10986339224728763.26E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9132370360rs10988449CTrs10988449220414583.00E-06Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers10988449-T
9134308491rs4740238GArs4740238208002211.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
9135632493rs12552369GArs12552369233776408.00E-06% improvement - 2 weeks1.16[1.10-1.21] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs12552369-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
9140266929rs9775457ACrs9775457229077300.00000315NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
9140266929rs9775457ACrs9775457229077300.0001026NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
101477202rs10794750CGrs10794750208002216.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
101478154rs4880851TCrs4880851208002213.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
101478171rs12267070CArs12267070208002213.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
101621911rs7894920CTrs7894920208002219.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
102270812rs3750590ATrs3750590208002212.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
102281519rs2014892TCrs2014892208002212.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
102291522rs11817443TCrs11817443208002212.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
103290142rs10508250CTrs10508250191071157.62E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
103867784rs11594834GTrs11594834224728765.32E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
104846626rs2397989GArs2397989200389478.37E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
105886149rs7098372TCrs7098372229077300.0002125NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
105886734rs2380205CTrs2380205229077300.0001326NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
105893268rs7894083ACrs7894083229077300.000089NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA,C
105898802rs7072174TCrs7072174229077300.000089NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
105900332rs907685AGrs907685229077300.000089NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
105900693rs907686GArs907686229077300.000089NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
105900822rs907688AGrs907688229077300.000089NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
105900973rs907689TCrs907689229077300.0001316NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
105904918rs2203197CTrs2203197229077300.000148NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
106292607rs2185691TCrs2185691pha0028509.67E-05phs0000201.48NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
108337245rs1892063AGrs1892063208002216.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
108350343rs11255628TCrs11255628208002215.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
109698647rs17517988ACrs17517988220471845.59E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1012517891rs4620627AGrs4620627208002214.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1013973579rs7904694CTrs7904694217507021.34E-05Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCFRMD4A
1014029313rs4748066TArs4748066200389478.79E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1014029639rs7917296GArs7917296200389477.10E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1014029701rs11258774GArs11258774200389479.31E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1014029742rs11258775TCrs11258775200389479.32E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1014030067rs7917812GArs7917812200389479.30E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1014030319rs4750446TGrs4750446200389479.32E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1014030692rs4748068TArs4748068200389476.21E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1014030921rs7922870CTrs7922870200389476.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1014038517rs4748075TCrs4748075200389479.40E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1015835277rs12262809GArs12262809208002218.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1015850183rs4387254CGrs4387254208002215.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1015858620rs11253656ATrs11253656208002218.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1015861275rs10795321CGrs10795321208002211.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1015861576rs10795322AGrs10795322208002214.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1015868012rs10904631CArs10904631208002215.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1015869590rs12264533AGrs12264533208002212.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1015889372rs7923528CTrs7923528208002211.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1015934272rs35785910CCAGrs7903674208002212.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1015934272rs7903674CGrs7903674208002212.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1018623463rs7093791AGrs7093791224728765.96E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1018631445rs7083127AGrs7083127224728765.32E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1018990315rs1542727AGrs1542727232901964.81E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1020806400rs16920587CGrs16920587203603151.98E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020806529rs16920589TArs16920589203603151.85E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020808390rs7910350TArs7910350203603151.68E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020810525rs16920624TGrs16920624203603157.00E-07whole sample16NA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020813062rs1339653GArs1339653203603151.65E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020813456rs1339654ATrs1339654203603152.26E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020842031rs7081156TCrs7081156203603151.01E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020857219rs11595329CGrs11595329203603152.33E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020864492rs12247444AGrs12247444203603152.33E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020865157rs11819199AGrs11819199203603152.33E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020880496rs11594336CTrs11594336203603152.76E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020895806rs16920700ACrs16920700203603152.14E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020897254rs11598280CTrs11598280203603151.85E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020897541rs11598341CTrs11598341203603152.51E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020897903rs11598854CTrs11598854203603157.67E-07NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020904153rs11593835CTrs11593835203603151.85E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1020907665rs2359537CTrs2359537203603152.27E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1021140255rs703088ACrs703088217507029.01E-06Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tANEBL
1021353120rs11599453CArs11599453229077300.0001671NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1021353120rs11599453CArs11599453229077300.0001866NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1021444603rs1751915GArs1751915229077300.000029NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1021449777rs11599589AGrs11599589229077300.0001624NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1024789614rs1556406TCrs1556406224728761.00E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1024791381rs2183696AGrs2183696224728769.94E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1024806631rs7090837GArs7090837224728761.61E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1024814503rs10828664GArs10828664224728765.55E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1025668778rs12762462GA,C,Trs12762462220471846.09E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1025823753rs7100942CArs7100942210423174.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1026019605rs2505449GArs2505449229077300.0001155NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1026463130rs1999240CArs1999240220599355.69E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1026463130rs1999240CArs1999240220599357.96E-04Sudden death suicides with a mood disorder vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1029010588rs10826503CTrs10826503229077300.0001378NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1029011821rs1360761CTrs1360761229077300.0002206NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1029204927rs1495673CArs1495673210423171.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1029252309rs10508741TA,C,Grs10508741210423177.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1029260154rs12765463CTrs12765463208002217.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1029264304rs12768785AGrs12768785208002217.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1029286539rs11007347ATrs11007347200389473.17E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1029290203rs6481557AGrs6481557200389477.63E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1029290352rs2250970CTrs2250970200389477.30E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1029291556rs1773860CTrs1773860200389471.42E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1029291556rs1773860CTrs1773860224728768.73E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1029291898rs1612122ATrs1612122200389477.00E-06NA1.17NA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionrs1612122-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1029316770rs2368950AGrs2368950208002213.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1030326776rs10826753CTrs10826753208002217.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1032358438rs16932874TCrs16932874208002211.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1032360053rs11008755TCrs11008755208002211.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1032363137rs11008756AGrs11008756208002211.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1032396902rs211413CArs211413208002216.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1032397358rs211415CTrs211415208002216.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1032397591rs211416TArs211416208002216.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1032566313rs1410232CTrs1410232208002214.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1032569039rs1041231CGrs1041231208002214.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033256863rs10827166GTrs10827166208002211.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033263267rs11009161TCrs11009161208002213.44E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033264180rs11009162AGrs11009162208002212.70E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033290343rs10827170GA,Crs10827170208002214.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033294775rs11009175GArs11009175208002215.00E-06NA0.16[NA] unit increase3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs11009175-AMeta-AnalysisResearch Support, N.I.H., Intramural
1033294775rs11009175GArs11009175232901965.40E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1033299356rs6481818CArs6481818208002216.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033299459rs6481819TCrs6481819208002216.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033306309rs11009183ACrs11009183208002212.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033311032rs12146170TCrs12146170208002211.61E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033328779rs10827173TArs10827173208002217.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033334273rs11009195TCrs11009195208002217.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033340331rs10430560TCrs10430560208002212.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033340399rs10430572CTrs10430572208002211.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033342307rs11009198CArs11009198208002211.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033342328rs11009199TCrs11009199208002211.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033342384rs11009200GCrs11009200208002211.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033343357rs7094668GArs7094668208002211.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033345201rs7078479CGrs7078479208002211.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033348045rs17230579GArs17230579208002219.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033348133rs11009203CGrs11009203208002217.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033349390rs10827177ATrs10827177208002212.27E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033351101rs10827178CTrs10827178208002213.60E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033356713rs11009208TArs11009208208002213.45E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033357713rs12355459TCrs12355459208002214.89E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033358070rs12359953CTrs12359953208002214.88E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033362132rs10827179CArs10827179208002212.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033365939rs11009213CTrs11009213208002216.97E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033366959rs11009216ATrs11009216208002219.15E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033369393rs10827183GArs10827183208002215.18E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033371103rs12571443GArs12571443208002214.94E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033373750rs10827186TCrs10827186208002218.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033374204rs16933929GCrs16933929208002218.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033374735rs11009222AGrs11009222208002218.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1033375914rs17296373GArs17296373208002214.73E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1034161048rs7082110AGrs7082110208002216.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1034257612rs1780436GArs1780436190651448.00E-06Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1034257612rs1780436GArs1780436216212693.00E-06NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1034257612rs1780436GArs1780436pha0028502.41E-06phs0000201.27NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNANANA
1043173569rs12413418TCrs12413418229077300.0000389NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1049756362rs747532CTrs747532229077300.0000938NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1049985110rs10857636CTrs10857636220414582.00E-07Bupropion, General SENANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers10857636-T
1053350411rs7923153CArs7923153216212698.68E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAPRKG1
1053393098rs3829170CTrs3829170216212695.80E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATPRKG1
1054240004rs4935325TCrs4935325220471843.76E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1054536839rs7899547TGrs7899547232901965.27E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1054669056rs7907283GArs7907283232901968.30E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1057358716rs41517949CTrs41517949198460673.33E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
1059282980rs10763492GArs10763492205161562.86E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
1059768050rs1930472GArs1930472229077300.0002457NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1059770449rs11006011GArs11006011229077300.0001885NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1059785181rs1930489CTrs1930489229077300.0002348NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1059788494rs871682CTrs871682229077300.0002348NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1060535920rs999845TCrs999845205161563.80E-08NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
1060535920rs999845TCrs999845229153520.000000312NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tABICC1
1060542694rs9416742GArs9416742205161561.82E-08NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyG
1060542694rs9416742GArs9416742229153520.00000097NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<30HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGBICC1
1060542694rs9416742GArs9416742229153520.00000152NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<35HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGBICC1
1060739778rs3894101CTrs3894101208002213.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1061669228rs7894427GTrs7894427224728764.19E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1061673772rs2440915GArs2440915224728764.38E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1061688953rs1684918AGrs1684918224728765.91E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1061709983rs7095688CTrs7095688224728763.07E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1062097331rs1380459CTrs1380459224728767.59E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1062136206rs10821745TGrs10821745224728764.29E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1062146576rs4948412TCrs4948412224728768.77E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1062161618rs4948417AGrs4948417224728766.69E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1062163327rs10994329CArs10994329224728766.57E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1062185494rs4948418CTrs4948418224728768.88E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1062222107rs10994359TCrs10994359224728763.09E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1062279124rs10994397CTrs10994397224728767.50E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1065817792rs10491072CTrs10491072191071151.39E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1067677739rs766031CTrs766031213168602.60E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATNA
1070475978rs10998399AGrs10998399208002218.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070482800rs10998401CGrs10998401208002216.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070618380rs10998462CGrs10998462208002218.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070618859rs1417941GArs1417941208002218.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070620026rs12766549TGrs12766549208002218.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070620366rs10823260TCrs10823260208002218.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070620429rs10998464TCrs10998464208002218.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070621501rs7078797CArs7078797208002218.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070622904rs7087811GArs7087811208002218.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070623185rs7088251GArs7088251208002218.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070626293rs12412524CGrs12412524208002218.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070626330rs10823263AGrs10823263208002218.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070626596rs7086993TCrs7086993208002216.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070628582rs7903209CTrs7903209208002216.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070629705rs7915930GArs7915930208002216.00E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070631783rs10082399GTrs10082399208002215.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070645376rs10509305ACrs10509305208002214.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070674178rs3740596AGrs3740596208002219.48E-06NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070712062rs2017305AGrs2017305208002219.00E-06NA0.22[NA] unit decrease3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs2017305-AMeta-AnalysisResearch Support, N.I.H., Intramural
1070712062rs2017305AGrs2017305232901969.00E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1070739630rs1539163CTrs1539163208002211.44E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070751024rs17471932GArs17471932208002212.53E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070779436rs12250707CTrs12250707208002211.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070782126rs2487710CArs2487710208002213.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070783522rs12266901TCrs12266901208002212.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070783580rs12244293AGrs12244293208002211.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070788552rs7476854AGrs7476854208002211.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1070791235rs12249735AGrs12249735208002217.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1071650837rs2763366GTrs2763366229077300.000103NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1071742701rs10999064AC,G,Trs10999064224728766.85E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1071895746rs4746965CTrs4746965208002216.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1071897998rs1053105CTrs1053105229077300.0001919NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1071907200rs7087051TGrs7087051213168607.61E-06Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
1071941253rs10740329ATrs10740329208002217.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1071944577rs7919014TCrs7919014208002218.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1071952322rs10762348CArs10762348208002219.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1073336877rs10999892TCrs10999892220471843.85E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1073337158rs10999893ATrs10999893220471844.50E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1073337454rs12266801CTrs12266801220471844.49E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1079043364rs717207GTrs717207213168606.15E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGKCNMA1
1079176594rs10740467CArs10740467240474463.86E-05NA1.29NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs10740467-A
1080635863rs522549GArs522549216212695.80E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
1080695125rs7918719GCrs7918719198460677.90E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
1080695173rs7903856TCrs7903856198460675.00E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
1082454295rs4934419AGrs4934419213168605.23E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
1082510802rs1647219CTrs1647219220471841.97E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1082545771rs11598010AGrs11598010220471845.55E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1082561348rs11592834TCrs11592834220471842.82E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1083194773rs1329198TCrs1329198208002218.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1085317970rs602012TCrs602012208002211.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1085343296rs11199316CTrs11199316208002215.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1085346520rs10788088TCrs10788088208002215.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1085349062rs10788092GCrs10788092208002215.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1085359998rs1324250GArs1324250208002219.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1085418969rs602840GCrs602840208002215.77E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1087545173rs3011695CTrs3011695200389479.40E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1088067925rs11201974TCrs11201974191071159.98E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATGRID1
1091022025rs11203054CArs11203054208002218.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1092548763rs10881832CTrs10881832224728766.12E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1092587500rs6583735CArs6583735224728762.83E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1094598259rs3740380CTrs3740380210423174.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1094618925rs11516919CTrs11516919210423172.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1094656941rs7094393TCrs7094393210423174.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1094663308rs7914571GArs7914571210423174.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1094736967rs2031616GArs2031616210423179.10E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1094740527rs7082214AGrs7082214210423179.50E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1094744904rs835247TGrs835247210423171.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1094755208rs835238TCrs835238210423171.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1095640551rs10786147TCrs10786147208002219.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095641393rs4917958GArs4917958208002219.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095641985rs7906044GCrs7906044208002219.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095650961rs12098741AGrs12098741208002219.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095652130rs7088236TArs7088236208002219.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095652487rs7898970AGrs7898970208002218.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095655566rs10786148TArs10786148208002218.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095656960rs7917744GTrs7917744208002218.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095658258rs11187724CGrs11187724208002218.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095659370rs11187725CTrs11187725208002218.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095663285rs3088126GArs3088126208002218.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1095664966rs10882364ATrs10882364208002216.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1096523073rs17882066GArs17882066245282841.15E-08(S-CT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1096523073rs17882066GArs17882066245282842.00E-16(S-DCT/S-CT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1096523083rs12773342TCrs12773342245282841.18E-08(S-CT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralT
1096523083rs12773342TCrs12773342245282842.00E-16(S-DCT/S-CT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralT
1096541982rs12571421AGrs12571421245282841.24E-08(S-CT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
1096541982rs12571421AGrs12571421245282842.00E-16(S-DCT/S-CT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
1096614725rs35709381GTrs35709381245282842.00E-16(S-DCT/S-CT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1096614725rs35709381GTrs35709381245282849.04E-09(S-CT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1096621103rs12569735AGrs12569735245282842.00E-16(S-DCT/S-CT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
1096621103rs12569735AGrs12569735245282848.65E-09(S-CT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
1096626202rs12573074TCrs12573074245282842.00E-16(S-DCT/S-CT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralT
1096626202rs12573074TCrs12573074245282848.66E-09(S-CT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralT
1096628105rs4589212ATrs4589212245282842.00E-16(S-DCT/S-CT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
1096628105rs4589212ATrs4589212245282848.83E-09(S-CT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
1096629341rs12763230GArs12763230245282842.00E-16(S-DCT/S-CT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1096629341rs12763230GArs12763230245282849.54E-09(S-CT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1096681000rs2181097GArs2181097245282842.00E-16(S-DCT/S-CT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
1096681000rs2181097GArs2181097245282844.51E-09(S-CT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
1096681846rs1074145GArs1074145245282842.00E-16(S-DCT/S-CT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1096681846rs1074145GArs1074145245282844.00E-09(S-CT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1097328227rs12255572AGrs12255572213168602.80E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
1097348845rs10882635GArs10882635213168608.63E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
1097383926rs501819ACrs501819191071155.39E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAALDH18A1
1097388162rs2275272GArs2275272229077300.0002276NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1097438823rs10882651CTrs10882651191071154.91E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACTCTN3
1098132016rs17479671CTrs17479671224728762.86E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1098794615rs12268044CTrs12268044208002213.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1098816373rs2255174CArs2255174208002213.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10102016044rs2270962CTrs2270962pha0028504.61E-05phs0000201.49NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAACWF19L1missenseNM_018294
10102092422rs10883460AGrs10883460208002218.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10102097695rs2060792TCrs2060792208002217.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10102121579rs3978768AGrs3978768208002213.61E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10105349816rs2236211GArs2236211224728763.63E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
10105350447rs7918186CTrs7918186224728763.82E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
10105352990rs729952GTrs729952224728763.42E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
10105362104rs11191741GArs11191741224728763.53E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
10105688341rs4917406AGrs4917406200389477.10E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
10106421057rs11192152GTrs11192152240474464.51E-05(Quantitative)0.53[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs11192152-T
10108789005rs6584786GArs6584786210423178.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
10113273136rs1914102AGrs1914102216212698.86E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
10114028538rs2419613AGrs2419613224728763.51E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
10114110893rs11195917GArs11195917198460675.56E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGGUCY2GP
10114971602rs7100692ACrs7100692210423179.20E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
10115317262rs11575624CTrs11575624208002218.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10115317711rs11575625GArs11575625208002218.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10115319661rs11575631CTrs11575631208002217.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10115321824rs11575634CTrs11575634208002218.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116188485rs11196739CTrs11196739208002214.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116189070rs4752727GArs4752727208002211.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116189170rs4752728GArs4752728208002211.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116189930rs11812741GArs11812741208002214.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116190274rs11196740GArs11196740208002214.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116190598rs7920422TCrs7920422208002212.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116190741rs4751905TCrs4751905208002212.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116190816rs12218918TCrs12218918208002213.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116192626rs3750820TCrs3750820208002213.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116193167rs17091846TGrs17091846208002218.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10116383343rs17719089GTrs17719089224728764.62E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
10117923225rs4751955AGrs4751955217507027.75E-07Suicidal ideation and behaviour in major depressive disorder (SCAN Suicidality (SSU) score)NANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGGFRA1
10120008097rs11198323GArs11198323208002218.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10120020264rs11594800TCrs11594800208002218.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10120218189rs17097692AGrs17097692216212695.65E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
10121171882rs12254134CArs12254134229077300.0000424NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
10121171882rs12254134CArs12254134229077300.0000424NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
10121175674rs17098857CTrs17098857229077300.0000833NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
10121175674rs17098857CTrs17098857229077300.0000833NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
10121190113rs915120TCrs915120229077300.0000115NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
10121190113rs915120TCrs915120229077300.0000115NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
10121190113rs915120TCrs915120229077300.0003308NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
10121865185rs1929675GTrs1929675197363532.40E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
10121919707rs7076024AGrs7076024208002212.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10121927156rs7909474GArs7909474208002216.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10121942694rs17099753GCrs17099753208002211.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10125488140rs1863735GArs1863735191071156.24E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
10126278648rs10430737TCrs10430737191071158.00E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACLHPP
10126785827rs1996667GArs1996667208002214.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10127081682rs17725710AGrs17725710216212698.29E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
10127081682rs17725710AGrs17725710pha0028504.00E-05phs0000201.3NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
10127097031rs6597703ACrs6597703216212696.18E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
10127097031rs6597703ACrs6597703pha0028501.78E-05phs0000201.28NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNANANA
10133441851rs11156442ACrs11156442216212699.52E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
10133461663rs10782374TGrs10782374216212694.24E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
10133533887rs7067998GCrs7067998208002217.00E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
10135380499rs2987799TGrs2987799197363531.20E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
111397897rs10832840CTrs10832840230914230.00000468NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
111398316rs4881745CTrs4881745230914230.0000037NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
115481973rs7942825CTrs7942825198460678.01E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT,COR51B5
115586168rs10742718CGrs10742718232901969.00E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
115586252rs10742719ACrs10742719232901966.13E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
115586545rs10742725CTrs10742725232901969.07E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
115602790rs2163946AGrs2163946232901969.57E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
115603975rs7930681CTrs7930681232901969.45E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
115604713rs11038193ATrs11038193232901966.91E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
115605154rs10769092TGrs10769092232901968.42E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
116179462rs325687TCrs325687208002214.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
116743890rs7942744CTrs7942744200389477.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
117022717rs1156526TCrs1156526210423178.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
117023541rs10769750AGrs10769750210423176.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
117023688rs7932579AGrs7932579210423175.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
117879176rs7112002ACrs7112002240474462.71E-05(Quantitative)0.44[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs7112002-A
117963498rs1355384TCrs1355384208002215.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
117964667rs11041683GArs11041683208002217.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118014777rs12420464GTrs12420464208002213.00E-06NA0.38[NA] unit decrease3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs12420464-TMeta-AnalysisResearch Support, N.I.H., Intramural
118014777rs12420464GTrs12420464232901963.30E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
118366148rs7938031CTrs7938031208002212.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118366256rs6578959GArs6578959208002214.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118368246rs7123904GArs7123904208002215.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118368490rs7113611TGrs7113611208002214.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118369292rs897109CArs897109208002211.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118369415rs897111GArs897111208002211.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118374548rs10840028CArs10840028208002213.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118599718rs12361165ACrs12361165208002211.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118694999rs7121168CArs7121168208002219.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118745081rs4370937TCrs4370937208002211.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118750553rs11042052CTrs11042052208002216.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118753717rs6484007CTrs6484007208002217.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118774923rs10743086GArs10743086208002216.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118799749rs11042064GArs11042064208002216.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118800504rs3913547AGrs3913547208002216.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118801618rs10840120ATrs10840120208002216.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118826779rs10840128AGrs10840128208002213.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118838660rs4929918GArs4929918208002218.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118838828rs2316863GTrs2316863208002218.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118842273rs6484606GArs6484606208002217.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
118848463rs7131166TGrs7131166208002218.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1110508938rs3802917TCrs3802917224728767.29E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1110702379rs4910167CArs4910167200389472.65E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1110792326rs10500731AGrs10500731200389477.57E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1111507780rs9888252GArs9888252231494480.0000455NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1113129163rs117020818GArs117020818245282847.00E-07(S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1113134780rs79847705GArs79847705245282847.07E-07(S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1115763070rs1385165GArs1385165229077300.0001922NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1116837874rs10832684AGrs10832684216212699.66E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAPLEKHA7
1116846313rs10832689CA,G,Trs10832689200389475.75E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1116873799rs417406CTrs417406200389473.93E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1116894090rs414992CTrs414992200389477.42E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1116896218rs428840AGrs428840200389473.99E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1116900362rs414219CGrs414219200389479.26E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1116902268rs381815CTrs381815200389472.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1116903178rs435206CArs435206200389473.20E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1116912986rs388968AGrs388968200389473.26E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1116917219rs11024074TCrs11024074200389471.42E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1116917430rs12418111CTrs12418111200389473.45E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1116917869rs7926335CTrs7926335200389472.07E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1116919677rs16933675ACrs16933675200389473.72E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1116925046rs177544CTrs177544200389479.89E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1118792880rs4074853TCrs4074853229077300.0001026NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1119244377rs924693CTrs924693237266689.97E-06NA1.62[1.27-2.05]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionrs924693-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1119451020rs11025135CTrs11025135224728762.36E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1119451505rs10500847TArs10500847224728763.91E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1119466720rs2632010GArs2632010224728766.20E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1119467431rs2046575TCrs2046575224728769.82E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1121171018rs12788723AGrs12788723208002216.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1121227564rs16907672GTrs16907672208002219.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1122863526rs4567455GCrs4567455200389478.19E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1122863658rs4550218CGrs4550218200389477.10E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1126772618rs10835065CA,G,Trs10835065200389471.87E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1126814230rs1868656GTrs1868656197363532.50E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1132286145rs11031676CTrs11031676190651443.50E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1132286145rs11031676CTrs11031676pha0028505.68E-05phs0000201.26NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNANANA
1132287944rs7944342TCrs7944342pha0028506.98E-05phs0000201.26NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNANANA
1132371215rs932503TCrs932503208002214.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1135229673rs1467558TCrs1467558220599354.31E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1135841576rs10501143TCrs10501143229077300.0000754NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1138349608rs1435154CArs1435154240474463.71E-05(Quantitative)0.93[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs1435154-C
1142913353rs1532096AGrs1532096217507021.61E-05Suicidal ideation and behaviour in major depressive disorder (SCAN Suicidality (SSU) score)NANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTNA
1144653664rs714679GArs714679229077300.0000571NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1145514565rs10838479TCrs10838479191071154.45E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1148234357rs11039588CA,G,Trs11039588216212691.16E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1158678335rs10896875AGrs10896875191071152.98E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1158746238rs1938791TCrs1938791191071153.03E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAALOC283194
1161699055rs2521567GArs2521567208002219.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1161705207rs2158027GArs2158027208002211.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1162786435rs10792369CTrs10792369229077300.0001722NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1162789763rs10897316GArs10897316229077300.0001491NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1163639881rs928948AGrs928948200389473.86E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1163659778rs10897459CTrs10897459200389472.78E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1163661512rs4980530ACrs4980530200389472.66E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1163664306rs7105288AGrs7105288200389479.75E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1163707203rs4980499GArs4980499200389472.03E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1163713317rs3740637GArs3740637200389472.01E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1163714319rs4980500TCrs4980500200389472.02E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1163738642rs11231662TGrs11231662200389478.44E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1163742553rs11231664TGrs11231664200389471.62E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1163743420rs11605797AGrs11605797200389471.50E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1163746120rs12800703AGrs12800703200389473.39E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1163759890rs11231670GTrs11231670200389471.29E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1163761169rs11231671CTrs11231671200389471.28E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1163771452rs492357CTrs492357200389472.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1163774597rs509701TCrs509701200389472.55E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1163775566rs504060TArs504060200389472.20E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1166493825rs10791889CTrs10791889224728761.16E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1166493825rs376610016CCTrs10791889224728761.16E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1166551143rs6591222CTrs6591222224728761.68E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1166560023rs4930390AGrs4930390224728761.72E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1166582210rs10750790AGrs10750790224728761.56E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1166583759rs7930203AGrs7930203224728761.50E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1166634397rs7948839CTrs7948839224728767.11E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1166660949rs4008953AGrs4008953224728769.45E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1168427244rs2156464AGrs2156464210423172.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1168445902rs2510387GArs2510387210423177.00E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1168446144rs2513297TCrs2513297210423174.50E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1168446424rs2187331CTrs2187331210423176.20E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1168522053rs3018712GArs3018712210423171.30E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1172234970rs11235520CArs11235520229077300.0001957NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1174768733rs4335576CTrs4335576208002219.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1176372052rs3740779AGrs3740779229077300.0001159NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1178795359rs7105794TCrs7105794213168603.27E-06Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATODZ4
1179052860rs7932591CGrs7932591220471845.78E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1179059444rs11237796AGrs11237796224728761.77E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179060796rs954129TArs954129224728761.50E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179062930rs17138171TCrs17138171224728765.23E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179067472rs11237799ACrs11237799224728765.88E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179068394rs7932890AGrs7932890224728766.03E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179075852rs17138230ATrs17138230224728761.07E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179077193rs12576775AGrs12576775224728761.14E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179083249rs1944449CTrs1944449224728769.85E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179083620rs12290811TArs12290811224728761.39E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179085846rs10501439AGrs10501439224728767.79E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179092736rs12276041GArs12276041224728769.04E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1179143454rs17138330TGrs17138330200389472.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1179306924rs12222648ACrs12222648229077300.0001118NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1179316999rs10899655CTrs10899655229077300.0000162NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1179316999rs10899655CTrs10899655229077300.0001376NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1179329267rs4945361TCrs4945361229077300.0001233NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1179381820rs6592863AGrs6592863208002219.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1179385675rs7939599GArs7939599208002219.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1179387954rs11237962CTrs11237962208002211.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1179388156rs11237964AGrs11237964208002212.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1179389769rs7124492TCrs7124492208002212.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1179389855rs7927582GArs7927582208002214.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1179389922rs7104818GCrs7104818208002212.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1179392225rs12578029TArs12578029208002212.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1179394407rs10899665AGrs10899665208002212.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1179401282rs2154746GArs2154746208002214.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1180072819rs1074543TCrs1074543208002215.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1180980888rs7941624AGrs7941624217507021.62E-04Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tANA
1180984220rs10897779GTrs10897779217507022.57E-04Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNA
1181799369rs575495AGrs575495210423179.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1183530138rs7924552AGrs7924552220471848.76E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1184238899rs17807611GCrs17807611224728761.58E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1184254393rs4145049GTrs4145049224728761.18E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1186103702rs10501615AGrs10501615224728762.76E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1188069313rs11019394AGrs11019394208002214.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1188086115rs10830733AGrs10830733208002215.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1188087528rs7107123AGrs7107123208002215.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1188089302rs10765483GCrs10765483208002216.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1188097159rs1470762CGrs1470762208002217.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1188101661rs7943537AGrs7943537208002219.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1188102482rs11019585GArs11019585208002217.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1188103181rs12807746TCrs12807746208002219.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1188243909rs308885GCrs526410231494480.0000171NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1188775773rs16924543ACrs16924543229077300.0001078NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1188791259rs1892879ACrs1892879229077300.0002095NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1189405190rs10047486AGrs10047486240474462.70E-05NA1.3NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
1189440231rs10830352GArs10830352240474461.21E-05(Quantitative)0.42[NA] unit decrease1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs10830352-A
1189466732rs17221829CArs17221829240474465.00E-06(Quantitative)0.44[NA] unit decrease1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs17221829-A
1191830717rs12793618GArs12793618232901967.86E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1193655091rs7117597AGrs7117597224728769.47E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1193662459rs10765647TCrs10765647224728767.20E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1193666263rs10501809GCrs10501809224728767.16E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1195785245rs7941059TGrs7941059210423178.70E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1195972510rs527077CTrs527077208002216.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1195975117rs573191CGrs573191208002216.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1196088967rs16923548ACrs16923548208002211.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1197176319rs1426651TCrs1426651230914230.00000229NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1197176319rs1426651TCrs1426651230914230.00000313NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1198457484rs11216033TCrs11216033210423175.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11100207500rs1216192CTrs1216192191071157.50E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAACNTN5
11100210203rs492107CArs492107191071151.01E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATCNTN5
11100223636rs501892AGrs501892191071157.05E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGCNTN5
11104923951rs508760GTrs508760232901965.87E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11105008884rs7107383ATrs7107383232901961.91E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11105041958rs1503389CTrs1503389232901961.06E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11105058220rs4754128GArs4754128232901961.86E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11105058837rs2409064GArs2409064232901961.30E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11106666059rs10890590GArs10890590217507021.46E-04Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGGUCY1A2
11107711836rs542931CA,G,Trs542931213168601.16E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGSLC35F2
11109416276rs7936391GArs7936391220471848.98E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
11110684462rs11819842GCrs11819842224728766.48E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11113864109rs897685CTrs897685197363531.60E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
11116662579rs651821CTrs651821210423174.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11118809882rs11217099CArs11217099208002212.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11118811641rs11606199GArs11606199208002211.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11120500339rs12577725CTrs12577725200389476.89E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
11120556341rs4445646TCrs4445646230914230.0008NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11121223996rs4936618ACrs4936618191071156.17E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
11126066224rs9326282GArs9326282208002213.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11126609067rs1106420ATrs1106420232901964.39E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11127109105rs2441692TGrs2441692208002212.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11127113172rs10893655GArs10893655208002212.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11127114387rs2322662CTrs2322662208002217.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11128466849rs2213018AGrs2213018240474462.76E-05(Dichotomous)1.41NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs2213018-G
11130339312rs731446TCrs731446210423172.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
11132081873rs3824870GArs3824870208002214.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11132233390rs1968652ACrs1968652208002211.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11132237417rs6590634TGrs6590634208002215.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11132239365rs10894539ACrs10894539208002217.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11132239708rs10894540CTrs10894540208002217.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11132637429rs11822374TCrs11822374220471848.12E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
11132645373rs2001903CArs2001903208002213.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
11132710240rs10160341GArs10160341208002212.01E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
122089230rs11062038TCrs11062038229077300.0002079NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
122363716rs2239037AGrs2239037208002214.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
122420377rs4765914TCrs4765914224728763.05E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
122420526rs10774037GArs10774037224728769.88E-08NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
124118317rs4238010GArs4238010191071156.00E-06NA1.72NA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs4238010-GNAANA
124416304rs4625554AGrs4625554233776409.00E-06% improvement - SSRI treated - 12 weeks0.19[0.11-0.28] unit increaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs4625554-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
125589409rs11063703AGrs11063703224728765.97E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
127162801rs3919533CTrs3919533200389476.99E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
127165114rs7311672AGrs7311672200389476.58E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
127174770rs2192137AGrs2192137200389475.24E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
128510463rs12830720TCrs12830720216212697.92E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANANALOC389634
128510463rs12830720TCrs12830720pha0028506.93E-05phs0000201.27NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANANALOC389634intronNR_024420
129027429rs7316141AGrs7316141197363532.30E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1211829309rs2541119AGrs2541119208002219.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1211830518rs2724625GCrs2724625208002219.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1213519996rs11055387GCrs11055387233776408.00E-06remission - SSRI treated - 12 weeks2.19[1.84-2.53] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs11055387-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1213641706rs1457614CArs1457614233776408.00E-06remission - 12 weeks1.47[1.29-1.64] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs1457614-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1214477187rs11055930TCrs11055930213168601.54E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATNA
1215159686rs10846109ACrs10846109210423173.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1215161833rs7969715GArs7969715210423173.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1215175698rs10846115TCrs10846115210423173.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1215313601rs4763421TCrs4763421216212696.31E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACRERG
1215733669rs3748299GArs3748299224728767.13E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1217325026rs11043347TGrs11043347210423175.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1217662235rs1706631ATrs1706631233776406.00E-06partial response - 2 weeks1.35[1.22-1.49] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs1706631-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1220276513rs2417849CTrs2417849208002213.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1220278266rs7964046TCrs7964046208002219.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1220278430rs2303658GArs2303658208002212.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1220279290rs11609944GArs11609944208002214.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1220279517rs17373317AGrs17373317208002215.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1224479494rs472100CTrs472100240474462.09E-05NA1.41NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
1226390319rs12424263TCrs12424263208002219.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1226579817rs6487552ACrs6487552208002211.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1226580124rs12426143CTrs12426143208002217.28E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1226585829rs7955200CTrs7955200208002218.38E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1232635183rs7961107AGrs7961107208002214.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1233408219rs7296488CTrs7296488231494480.0000458NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1239932451rs11172502ATrs11172502208002219.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1239947325rs11172566TCrs11172566208002219.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1239980523rs11172696TCrs11172696208002219.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1242232875rs7316176TCrs7316176200389479.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1242892740rs11181527CTrs11181527208002217.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1242893132rs11181528AGrs11181528208002215.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1242895401rs10785342AGrs10785342208002216.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1242916073rs2708079TCrs2708079208002218.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1242917248rs1376930TGrs1376930208002211.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1242925175rs10880312AGrs10880312208002216.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1242927331rs1669943GArs1669943208002214.49E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1242929397rs2034614GArs2034614229077300.0001726NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1242934707rs1452106AGrs1452106208002211.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1242991138rs10785350CTrs10785350208002216.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245367674rs17095280CArs17095280208002219.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245374324rs1395395GArs1395395208002219.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245374799rs12310696CTrs12310696208002219.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245383372rs6582526CTrs6582526208002219.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245388817rs4768582AGrs4768582208002215.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245389301rs4768584TGrs4768584208002215.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245394369rs13328953AGrs13328953208002215.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245394863rs7315173AGrs7315173208002215.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245395168rs7299805CGrs7299805208002215.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245396231rs10880724AGrs10880724208002215.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245396892rs7315747CGrs7315747208002215.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245397762rs12819320TGrs12819320208002215.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245398438rs12579631ACrs12579631208002215.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245399428rs10880726CTrs10880726208002216.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1245733422rs12579771CTrs12579771190651442.20E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1245733422rs12579771CTrs12579771216212691.20E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACANO6
1245733422rs12579771CTrs12579771pha0028502.29E-05phs0000201.3NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACANO6intronNM_001025356
1246493582rs11183341ATrs11183341208002219.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1249146947rs10783282GArs10783282230914230.000000617NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249146947rs10783282GArs10783282230914230.00000116NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249383207rs7311091CTrs7311091224728764.01E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249390677rs10783299TCrs10783299224728761.09E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249398862rs2293445GArs2293445224728761.01E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249416944rs10875912TCrs10875912224728767.14E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249419677rs11168827GCrs11168827224728768.75E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249422094rs10875914AGrs10875914224728761.40E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249424616rs11614738GArs11614738224728765.05E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249436724rs12580349AGrs12580349224728764.44E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249442813rs2304275TCrs2304275224728761.78E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249444545rs2241726GArs2241726224728763.71E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249464449rs7969091AGrs7969091224728761.26E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249474605rs12821008CTrs12821008224728761.95E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249478658rs6580698TCrs6580698224728769.13E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249478812rs6580699TGrs6580699224728761.09E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249479968rs7296288ACrs7296288224728761.33E-07NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249480948rs2117028GArs2117028224728763.64E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249498130rs10783302GTrs10783302224728762.14E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1249501398rs1274726CTrs1274726224728761.13E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1252651010rs2852453CTrs2852453229077300.0001276NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1252657665rs1902763TCrs1902763229077300.0000346NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1252657665rs1902763TCrs1902763229077300.0000562NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1252666920rs1945300AGrs1945300229077300.0000328NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1252666920rs1945300AGrs1945300229077300.000068NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1252675917rs2608017GArs2608017229077300.0000681NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1252675917rs2608017GArs2608017229077300.0001261NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1252681925rs6580873AC,Trs6580873229077300.0000461NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC,A
1252681925rs6580873AC,Trs6580873229077300.0001514NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC,A
1255498520rs7966464CArs7966464208002219.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255518567rs11171301AGrs11171301208002217.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255553675rs11171338GArs11171338208002217.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255598126rs11504009CTrs11504009208002219.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255618069rs1478732GTrs1478732208002219.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255620711rs1382489GArs1382489208002219.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255621746rs999131GArs999131208002219.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255633142rs12311227GArs12311227208002217.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255636519rs7968976GTrs7968976208002219.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255637349rs7301102TGrs7301102208002217.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255637505rs7315945GArs7315945208002216.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255638275rs11612625GArs11612625208002216.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255638384rs11608600AGrs11608600208002216.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255638709rs7137816AGrs7137816208002216.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255638811rs7309099TArs7309099208002216.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255639107rs7138444CTrs7138444208002216.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255639304rs7138584AGrs7138584208002216.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255641075rs7301705AGrs7301705208002215.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255641255rs4522268CTrs4522268208002215.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255641295rs4388990AGrs4388990208002214.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255641328rs6581025GArs6581025208002214.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255665948rs10876736GArs10876736208002213.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255669474rs12303191CTrs12303191208002213.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255673008rs12310560CTrs12310560208002214.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255677023rs12308170GArs12308170208002214.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255746910rs10783724GArs10783724208002219.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1255818508rs7487750AGrs7487750208002219.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1259910672rs276086TCrs276086208002214.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1259935109rs276014GArs276014208002217.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1262395774rs7963802AGrs7963802229077300.0002031NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1263344993rs1081780CTrs1081780208002212.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1263530245rs1587097CTrs1587097191071156.18E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1264711766rs7133188CTrs7133188229153520.000016NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tCC12orf56
1264717742rs1865801TCrs1865801229153520.000000135NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<25HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCC12orf56
1264717742rs1865801TCrs1865801229153520.00000149NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<20HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCC12orf56
1264717742rs1865801TCrs1865801229153520.0000929NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tCC12orf56
1264863983rs11837890GTrs11837890200389473.75E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1264870510rs11829120CArs11829120200389473.97E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1264874102rs7303577ACrs7303577200389476.37E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1264877053rs4075094TArs4075094200389474.24E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1267289743rs983665TCrs983665213168601.21E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATNA
1267294461rs924822GTrs924822213168601.82E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1269031913rs11177321GArs11177321240474464.94E-05(Quantitative)0.6[NA] unit decrease1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs11177321-A
1269040055rs2920022GArs2920022197363531.90E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1269370756rs9943849CTrs9943849206738763.00E-06NA1.37[1.20-1.56] 597 German cases; 1,295 controlsNOPOP(1295)German(597)ALL(1892)NOPOP(1295)EUR(597)ALL(1892)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs9943849-TResearch Support, Non-U.S. Gov't
1269663047rs10878951CTrs10878951208002216.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1271143758rs4760933AGrs4760933191071151.39E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAPTPRR
1272232292rs328761AGrs328761200389479.76E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1272672823rs4584622CTrs4584622237266682.00E-04NA1.64[1.28-2.10]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionrs4584622-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1273776884rs7295470TCrs7295470232901963.75E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273782526rs10785027ATrs10785027232901962.30E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273783120rs1520550GArs1520550232901962.23E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273784155rs2139680ATrs2139680232901961.59E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273784488rs7485858TCrs7485858232901961.37E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273785077rs7978337ATrs7978337232901961.50E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273796472rs7308693CTrs7308693232901963.33E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273797508rs10785028GTrs10785028232901963.38E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273801249rs7137885TCrs7137885232901963.42E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273805442rs10748226GTrs10748226232901964.60E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273807517rs7975033ATrs7975033232901965.94E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273811639rs1915293CTrs1915293232901966.24E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273813659rs6582151TCrs6582151232901964.91E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273814053rs6582152CGrs6582152232901968.11E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273816760rs7964705CTrs7964705232901966.17E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273818611rs4760780CTrs4760780232901964.60E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273820610rs2203976CTrs2203976232901964.87E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273821580rs7953276ACrs7953276232901964.43E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273827434rs2363065CTrs2363065232901965.37E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273830392rs1356893CTrs1356893232901962.85E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273831656rs2139675GTrs2139675232901964.93E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273838741rs988542GArs988542232901964.39E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273870560rs10879604ATrs10879604232901963.26E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273870866rs10879605TCrs10879605232901964.13E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273879749rs6421241CTrs6421241232901967.65E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273899480rs7976937TCrs7976937232901965.38E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273901385rs12368237GArs12368237232901967.61E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273901869rs1545292AGrs1545292232901967.83E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273902551rs7974278GCrs7974278232901967.87E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273907497rs11179680GArs11179680232901965.64E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273907547rs11611073GArs11611073232901965.86E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273907688rs11179681AGrs11179681232901967.14E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273907923rs12824659GArs12824659232901965.79E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273908486rs1443742TCrs1443742232901967.66E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273914088rs1443738TGrs1443738232901967.18E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273914791rs1443737TArs1443737232901966.70E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273917539rs12367407ATrs12367407232901966.27E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273918395rs11179688GTrs11179688232901969.70E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273919717rs11179690GArs11179690232901969.75E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273925841rs11179697GArs11179697232901966.74E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1273930019rs7316126TArs7316126232901969.88E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1276326273rs12809711TCrs12809711216212695.48E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
1276357686rs17115989ACrs17115989198460671.54E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
1279456455rs11112562TArs11112562208002216.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1279737843rs1002491CTrs1002491240474464.48E-05NA3.93NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
1281542215rs1435964TCrs1435964237266686.77E-06NA1.61NA869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1281544536rs10492002CTrs10492002237266684.00E-06NA1.64[1.33-2.00]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1281549675rs7132119CArs7132119237266681.05E-05NA1.61NA869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1281901318rs10746190CArs10746190200389474.35E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1281904122rs1879800CTrs1879800200389474.40E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1281932981rs2400954CTrs2400954200389479.39E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1281933208rs2400955TCrs2400955200389475.65E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1282076089rs10862339ACrs10862339210423171.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1282081470rs1344016TCrs1344016210423172.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1282105383rs10778827TCrs10778827210423176.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1283609398rs1400878ACrs1400878208002219.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1283610880rs11833219TGrs11833219208002219.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1284564068rs1545843GArs1545843215216121.00E-09NA1.4[1.25-1.56] 353 European ancestry cases; 366 European ancestry controlsEuropean(719)ALL(719)EUR(719)ALL(719)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs1545843-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1289471235rs7960664GArs7960664216212695.21E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1289471235rs7960664GArs7960664pha0028509.96E-05phs0000201.33NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
1289669785rs2638463GArs2638463210423172.90E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1289675376rs2638470GArs2638470210423173.60E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1292016754rs3943102TCrs3943102208002213.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1292029403rs11106222GArs11106222208002219.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1292031586rs11106224TGrs11106224208002213.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1292041027rs7980683CTrs7980683208002213.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1292045625rs10777319GArs10777319208002213.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1292046691rs6538287TCrs6538287208002213.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1292050477rs10859174ATrs10859174208002213.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1292050768rs1352642GArs1352642208002213.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1292531608rs790575TGrs790575229077300.0000203NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1292534370rs35666GTrs35666229077300.0001161NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1292615618rs17020113CTrs17020113229077300.0002277NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1292664512rs7980688TCrs7980688229077300.0000717NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1292806197rs4760440AGrs4760440224728762.88E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1292813646rs1515569AGrs1515569224728763.72E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1292818786rs1515565AGrs1515565224728762.54E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1292819139rs1515563ACrs1515563224728762.59E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1292824593rs6538329TGrs6538329224728762.05E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1292860563rs552398AGrs552398224728765.00E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1293167435rs17194416GCrs17194416216212697.32E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACEEA1
1295959788rs7136572AGrs7136572220414583.00E-07Bupropion, SexNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers7136572-G
1295995906rs10859907TCrs10859907229077300.00021NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1299177369rs11109604TCrs11109604229077300.0001359NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1299430469rs4762546GCrs4762546210423174.00E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
12100025158rs1587504TCrs1587504231494480.0000634NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
12101276216rs10860652CTrs10860652208002219.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101522078rs1849710CGrs1849710208002217.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101525373rs3914433CTrs3914433208002219.54E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101525562rs7300078GTrs7300078208002212.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101526064rs11110670TCrs11110670208002213.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101528318rs905610CGrs905610208002212.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101528576rs905611TCrs905611208002212.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101529494rs4764639GTrs4764639208002212.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101530391rs6538976CArs6538976208002214.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101530566rs7298531CTrs7298531208002212.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101531938rs9804950TCrs9804950208002212.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101533066rs12313926TCrs12313926208002214.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101533421rs11110674ACrs11110674208002212.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101533459rs12370713TCrs12370713208002211.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101534166rs2137889ACrs2137889208002213.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101534218rs2137890AGrs2137890208002212.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101535175rs10860685TCrs10860685208002214.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101535644rs10860686CTrs10860686208002212.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101536053rs11110675GArs11110675208002213.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101536192rs11110676TArs11110676208002212.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101536561rs11110677AGrs11110677208002212.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101537699rs11110678CTrs11110678208002212.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101550176rs2279834TCrs2279834208002212.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12101565885rs7138043CTrs7138043208002211.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12104754500rs77724872CTrs77724872245282847.00E-07(S-DCT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
12104995459rs3812796TCrs3812796191071156.21E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAACHST11
12105035423rs1164856ACrs1164856191071151.77E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACCHST11
12105038670rs2694418GTrs2694418191071159.61E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACCHST11
12105926455rs1358221TCrs1358221208002219.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12106593949rs2173595CTrs2173595229077300.0002226NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
12107732227rs7953431TGrs7953431216212696.46E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGBTBD11
12107743775rs1863538ACrs1863538216212693.32E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGBTBD11
12107767730rs11113292GArs11113292216212695.39E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGBTBD11
12108061806rs4964604CTrs4964604229077300.0000959NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
12108228298rs6539369AGrs6539369200389472.92E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
12108240832rs1895943CArs1895943200389478.70E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
12108242007rs6539377CTrs6539377200389472.37E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
12108247815rs11113550AGrs11113550200389472.71E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA,G
12110188155rs7971523GCrs7971523208002215.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12110195100rs10774883GArs10774883208002214.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12110201605rs10850708TCrs10850708208002213.43E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12112645401rs2074356GArs2074356233776406.73E-11NANANAUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
12112817783rs11066280TArs11066280233776401.44E-08NANANAUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
12113878391rs16934262TGrs16934262220471848.81E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
12114885632rs7303913GArs7303913208002213.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12114887730rs16944310TCrs16944310208002215.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12114900429rs12229163TCrs12229163208002219.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12114910700rs5025219TArs5025219208002219.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12114913891rs3914952TCrs3914952208002216.43E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12114915022rs3858618TArs3858618208002215.59E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12114942504rs11067148CTrs11067148208002212.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12116176053rs17774603ACrs17774603220471843.97E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
12116176575rs16946143CTrs16946143220471842.02E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
12116179237rs868451CArs868451220471844.59E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
12116180354rs11610288ACrs11610288220471844.56E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
12116183484rs1084062ACrs1084062220471849.63E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
12116220550rs3906005CTrs3906005216212697.28E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
12117050611rs7304254CArs7304254224728763.35E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
12117051036rs17615758CTrs17615758224728761.34E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
12119454647rs7138083CGrs7138083237266682.00E-04NA1.96[1.39-2.78]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
12124646827rs4765078TCrs4765078190651443.50E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
12124646827rs4765078TCrs4765078216212693.34E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATZNF664-FAM101A
12124646827rs4765078TCrs4765078pha0028501.67E-05phs0000201.23NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATZNF664-FAM101AintronNM_001204299
12124676823rs11057500CTrs11057500200389475.56E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
12124683205rs10846630CTrs10846630200389476.54E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
12125431990rs3803143CTrs3803143208002215.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12125776130rs7306356CTrs7306356205161561.07E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
12125789999rs12425883GCrs12425883220471841.90E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
12125791463rs2088707GArs2088707220471844.78E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
12127813229rs2656825ATrs2656825208002217.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127813442rs2695952CTrs2695952208002214.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127813741rs10744304GArs10744304208002219.00E-06NA0.15[NA] unit decrease3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs10744304-AMeta-AnalysisResearch Support, N.I.H., Intramural
12127813741rs10744304GArs10744304232901968.70E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
12127815086rs2656824CTrs2656824208002212.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127815178rs2593270GArs2593270208002214.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127815260rs2656823AGrs2656823208002212.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127815488rs2656822CTrs2656822208002212.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127815644rs2593272AGrs2593272208002212.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127816124rs2593273CTrs2593273208002215.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127816203rs4765531CArs4765531208002214.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127816280rs2921983TCrs2921983208002214.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127816720rs1700400CTrs1700400208002211.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12127826818rs7979980TCrs7979980208002212.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12128421906rs2633467TGrs2633467208002213.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12129781378rs10773632GArs10773632208002219.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
12130159705rs264501GTrs264501224728762.17E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
12130895518rs11609204CTrs11609204220471846.26E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
12130895719rs10848096TGrs10848096220471843.95E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
12130897752rs11060870CTrs11060870220471849.76E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
12131030163rs12231658GArs12231658229077300.0001691NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
12131045190rs12809631CArs12809631229077300.0000333NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
12131045190rs12809631CArs12809631229077300.0000774NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
12131933350rs883673CGrs883673231494480.0000655NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
12131970306rs11061558AGrs11061558231494480.0000326NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
12133022983rs11146962AGrs11146962229077300.0000889NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1321552462rs7990975CTrs7990975210423171.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1321583572rs11841745AGrs11841745210423172.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1322320178rs7317531GTrs7317531232901968.59E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1322350875rs749170CTrs749170229077300.0002281NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1322385730rs9316567TCrs9316567pha0028506.58E-05phs0000201.23NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNANANA
1323747532rs7327420AGrs7327420224728768.77E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1323964095rs7339176GArs7339176232901967.01E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1323966145rs1008812AGrs1008812232901965.80E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1323966252rs1008813GArs1008813232901965.77E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1323966395rs1008814TArs1008814232901966.16E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1323967078rs8000066CTrs8000066232901966.60E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1323970877rs11618590TCrs11618590232901967.81E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1324658356rs9805786GTrs9805786220641627.00E-06NA1.65[1.33-2.05] 467 European ancestry cases; 407 European ancestry controlsEuropean(874)ALL(874)EUR(874)ALL(874)Depression and alcohol dependenceHPOID:0000716DepressionDOID:303DOID:1596substance-related disordermental depressionD003863DepressionNANADepressionDrug abuseNA
1325120453rs9551113AGrs9551113200389475.96E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1325808286rs9551188ACrs9551188220471841.02E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1325810823rs9319209TArs9319209220471841.30E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325816715rs17082017CTrs17082017220471844.56E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1325818110rs12431317TCrs12431317220471842.45E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325820101rs9553567TCrs9553567220471841.05E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325821603rs8262AGrs8262220471842.14E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325823207rs7999040TArs7999040220471842.95E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325823919rs9553568CTrs9553568220471842.50E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1325824906rs9553570GArs9553570220471843.49E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1325825574rs12431141GArs12431141220471841.24E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1325825889rs4312169TCrs4312169220471848.84E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325831888rs7995033TCrs7995033220471841.23E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325837097rs9553572CTrs9553572197363535.90E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1325837097rs9553572CTrs9553572220471844.88E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1325840828rs12427761TCrs12427761220471842.37E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325841842rs4594103TArs4594103220471847.08E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325842806rs17082070CTrs17082070220471845.34E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325845860rs4468451GCrs4468451220471841.05E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1325846200rs9645860TCrs9645860220471843.32E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325846645rs9581311TCrs9581311220471847.83E-06Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1325849146rs12430251TGrs12430251220471842.55E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1325853989rs7995484AGrs7995484220471846.03E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1325860031rs9511740CGrs9511740220471843.29E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1325860273rs7982860ACrs7982860220471841.51E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1325860926rs12431091GCrs12431091220471841.58E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1327497264rs4771046AGrs4771046208002213.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1327497653rs9512446GArs9512446208002211.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1327497791rs9512447GArs9512447208002219.35E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1331403677rs9506356AGrs9506356208002216.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1331408076rs9508846GArs9508846208002213.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1331412128rs7328020CArs7328020208002214.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1331427259rs1125434GArs1125434208002212.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1331427866rs9569027CTrs9569027208002212.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1331429657rs213587GArs213587208002212.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1331430486rs1831549TCrs1831549208002212.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1331431275rs213584GCrs213584208002212.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1331431984rs1999420AGrs1999420208002212.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1331603057rs9535050AGrs9535050232901961.72E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1331604816rs4942783GCrs4942783232901961.85E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1331605117rs2312972CTrs2312972232901962.18E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1331605269rs2312971GCrs2312971232901961.76E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1331606120rs11147450CTrs11147450232901963.18E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1331606961rs9535127TCrs9535127232901964.59E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1331607186rs9596054AGrs9596054232901963.04E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1331990519rs11841788AGrs11841788217507023.14E-05Suicidal ideation and behaviour in major depressive disorder (SCAN Suicidality (SSU) score)NANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tANA
1332618005rs456705TGrs456705229077300.0001556NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1332870906rs9534093GTrs9534093213168605.75E-06Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
1332963529rs11571801CGrs11571801208002217.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1333070506rs2010997GArs2010997208002215.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1338860697rs2455415CTrs2455415216212691.44E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1340473525rs2224846GArs2224846200389476.77E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1340473991rs9548967TCrs9548967200389476.49E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1340476109rs9548968GArs9548968200389477.17E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1340478401rs9566483TCrs9566483200389476.32E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1340478755rs9548970AGrs9548970200389476.45E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1340479576rs9548971CTrs9548971200389476.41E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1340480447rs9576916AGrs9576916200389476.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1340483478rs9548973CTrs9548973200389478.76E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1340484556rs9576917AGrs9576917200389476.54E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1340485863rs7140080GTrs7140080200389475.74E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1340487456rs9532454GArs9532454200389475.42E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1340490129rs9548974TCrs9548974200389476.63E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1340490173rs9548975AGrs9548975200389476.48E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1340491103rs4943713AGrs4943713200389476.08E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1340492588rs7317907ACrs7317907200389475.76E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1340493659rs9548978TCrs9548978200389475.24E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1340493988rs9566485GArs9566485200389475.06E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1340494969rs9532457TGrs9532457200389474.89E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1340496029rs2209239CTrs2209239200389474.65E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1340496045rs2209240GArs2209240200389474.36E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1340498629rs12019497CArs12019497200389474.31E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1340499917rs9548982GTrs9548982200389473.93E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1340572053rs7339164GArs7339164217507021.54E-05Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNA
1340572070rs276420TGrs276420217507022.96E-05Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tANA
1340602347rs9603665CTrs9603665217507021.29E-04Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCNA
1340702657rs9549067GArs9549067205161562.99E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyG
1341898147rs9562287TGrs9562287208002218.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341898405rs9566743AGrs9566743208002218.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341907826rs11620416AGrs11620416208002214.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341912190rs9562289TGrs9562289208002214.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341928314rs7321509AGrs7321509208002213.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341928593rs9562292TArs9562292208002213.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341933464rs9566753TCrs9566753208002213.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341933637rs9566754AGrs9566754208002213.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341935250rs3829396CA,G,Trs3829396208002214.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341937790rs9562293TCrs9562293208002214.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341938284rs9562294TCrs9562294208002214.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341940597rs9566755AGrs9566755208002214.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341943052rs9562295ATrs9562295208002214.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341948125rs9566757AGrs9566757208002214.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341960630rs11620020TGrs11620020208002218.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341961175rs9562297TArs9562297208002216.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341962997rs3923988AGrs3923988208002215.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1341985154rs11616683AGrs11616683208002213.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1342076415rs348254TArs348254208002212.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1342077774rs1179957TGrs1179957208002217.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1342151623rs1023243GArs1023243229153520.00000288NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tAKIAA0564
1342770696rs11617266GArs11617266216212698.52E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGDGKH
1342773061rs9566937GArs9566937216212694.08E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGDGKH
1342811550rs9590678TArs9590678216212695.58E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
1342812356rs9533044AGrs9533044216212696.99E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1343160930rs2324851AGrs2324851216212698.63E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATTNFSF11
1343185106rs9533171GTrs9533171216212692.81E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
1343798348rs2289774TCrs2289774224728766.45E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1343798406rs1037023CTrs1037023224728766.18E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1343834270rs17538444CTrs17538444233776404.00E-07% improvement - SSRI treated - 12 weeks0.39[0.24-0.54] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs17538444-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1343859983rs7338766TCrs7338766208002215.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1343861926rs4942197GCrs4942197208002216.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1343863718rs1117942CArs1117942208002216.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1344241773rs1032520CTrs1032520229153520.000016NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tCENOX1
1344842503rs9525927GArs9525927229077300.0002153NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1345657195rs7323288AGrs7323288210423178.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1345674773rs17066439CTrs17066439210423176.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1346845976rs259730TCrs259730240474461.52E-05(Dichotomous)1.49NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs259730-C
1350949948rs12864797GTrs12864797208002219.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1350960378rs200220ACrs200220208002214.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1351068575rs1262775TCrs1262775224728767.27E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1351075385rs1630605CTrs1630605224728768.07E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1356115403rs9537164GArs9537164191071157.34E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAG,ANA
1360865719rs17184874CTrs17184874208002215.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1360866744rs17789007CTrs17789007208002215.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1365215262rs9592359AGrs9592359191071154.87E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1365229479rs359349AGrs359349191071152.72E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1365232024rs359357AGrs359357191071157.38E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
1369433788rs1659025CTrs1659025213168603.80E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
1369791693rs9634953GTrs9634953208002214.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1369795334rs2152563GArs2152563208002215.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1369880146rs17605645TGrs17605645208002214.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1370177551rs9572198GTrs9572198231494480.00000289NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1370846203rs9572423GArs9572423201250889.00E-06NA1.54NA1,020 European cases; 1,636 European controlsEuropean(2656)ALL(2656)EUR(2656)ALL(2656)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs9572423-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1371339627rs1280903GCrs1280903216212697.05E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
1371798043rs9564791TCrs9564791210423171.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1373026724rs2182003GArs2182003224728763.70E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1373095271rs9542990GArs9542990229077300.000016NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1373095271rs9542990GArs9542990229077300.000062NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1373100056rs1924939CTrs1924939224728764.96E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1373100056rs1924939CTrs1924939229077300.0000236NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1373100056rs1924939CTrs1924939229077300.0000467NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1373104056rs4885005TCrs4885005229077300.0000996NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1375024613rs6562826AGrs6562826224728762.27E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1375296809rs1359873TCrs1359873229077300.0000476NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1378225665rs2813740CTrs2813740197363534.40E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1378721716rs2763404CTrs2763404208002219.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1379397209rs17770207CTrs17770207216212696.13E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1379550458rs7337382GArs7337382208002211.86E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1379550934rs7319358CTrs7319358208002211.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1379551013rs7319850GArs7319850208002214.98E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1379551294rs4885589CTrs4885589208002211.25E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1379556040rs1888678GTrs1888678208002211.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1379561176rs4572267CTrs4572267208002219.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1379563430rs9544946GArs9544946208002218.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1380169004rs9601248CTrs9601248233776402.00E-06remission - 12 weeks1.38[1.25-1.52] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs9601248-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1381357671rs11149178GArs11149178233776407.00E-06% improvement - SSRI treated - 12 weeks0.18[0.1-0.26] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs11149178-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1381493965rs4379965CArs4379965198460678.05E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
1384130232rs6563353CTrs6563353227605532.00E-06EA + AA - GSENANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs6563353-A
1384976969rs7490744TGrs7490744210423171.30E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1384978573rs9602470AGrs9602470210423175.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1385265635rs4480680TCrs4480680224728768.15E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1385285674rs6563407AGrs6563407224728766.19E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1385285855rs7985182GCrs7985182224728764.34E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1385571238rs11838719CTrs11838719210423177.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1391226105rs17553281ATrs17553281232901963.25E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1394087948rs2762089TArs2762089232901969.69E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1394095160rs1373834AGrs1373834232901968.01E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1394097045rs9524069CArs9524069232901966.94E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1394097301rs9516233CTrs9516233232901966.69E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1394101539rs973303GTrs973303232901967.31E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1394101658rs4412846ATrs4412846232901967.84E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1395076249rs7989427TArs7989427208002219.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1396001195rs10508015TCrs10508015208002214.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1396001280rs12584768TCrs12584768208002217.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1396001330rs9524936CGrs9524936208002213.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1396001349rs9524937TGrs9524937208002213.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1396003663rs9516572CTrs9516572208002219.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1396006041rs11843128AGrs11843128208002219.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1396006171rs11841659CTrs11841659208002219.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1397023829rs9554349CTrs9554349232901963.18E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1397807422rs9556684CGrs9556684208002219.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1397812638rs4603415GArs4603415208002219.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1397817733rs9556686CGrs9556686208002217.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1397953046rs4441122CArs4441122220599353.04E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1397954425rs4771992GTrs4771992220599352.62E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1398514241rs1538187GArs1538187231494480.0000517NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1399803593rs7331698CTrs7331698229077300.0002426NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
13100259210rs912659CTrs912659200389478.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
13101134343rs2038672AGrs2038672224728764.28E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
13101677816rs9645898ACrs9645898232901965.33E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
13101699325rs9554751GArs9554751220471849.04E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
13102582443rs2476230GCrs2476230237266682.00E-04NA1.69[1.31-2.17]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionrs2476230-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
13102626423rs2476236AGrs2476236208002216.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13102627154rs4772431AGrs4772431208002214.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13102627365rs2476238CArs2476238208002215.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13102773019rs660557AGrs660557208002218.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13102773028rs478543CTrs478543208002218.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13102773400rs648465AGrs648465208002218.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13102775098rs674312TCrs674312208002218.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13102775616rs502094CTrs502094208002217.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13102776029rs498351CGrs498351208002219.00E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13102778965rs615746CTrs615746208002219.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13102794587rs636559CTrs636559208002214.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103595035rs9557964TArs9557964208002219.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103600902rs2078284TCrs2078284208002216.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103988360rs1411651GArs1411651208002213.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103988495rs1411650TCrs1411650208002213.52E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103988531rs1411649AGrs1411649208002213.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103988923rs17298539TCrs17298539208002213.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103990227rs951347CTrs951347208002214.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103990454rs9518987CTrs9518987208002214.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103991614rs7994713GCrs7994713208002214.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103991629rs7994851GArs7994851208002216.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103991671rs9518991TGrs9518991208002214.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103991727rs9518992GCrs9518992208002214.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103991818rs9518993AGrs9518993208002214.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103992269rs9518999TCrs9518999208002214.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103993369rs9514121CTrs9514121208002214.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103993701rs9519003ACrs9519003208002215.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103993802rs9519004AGrs9519004208002215.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103994250rs9519011GArs9519011208002215.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103994378rs9519012AGrs9519012208002215.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103994807rs10162020AGrs10162020208002215.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103994822rs10161695TCrs10161695208002215.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103995069rs7991857CTrs7991857208002218.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103995145rs7992025CTrs7992025208002219.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13103996052rs7998553GArs7998553208002215.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105415609rs1652879CTrs1652879208002218.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105416059rs4281575CTrs4281575208002211.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105417378rs1337153ATrs1337153208002211.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105418388rs2782987TCrs2782987208002213.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105418533rs2567004GArs2567004208002213.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105418641rs2782989CTrs2782989208002216.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105422464rs9586631GArs9586631208002211.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105422917rs9558386GArs9558386208002212.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105423946rs9555088GArs9555088208002211.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105424397rs9558392ACrs9558392208002211.86E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105424546rs9558393TCrs9558393208002219.32E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105424713rs9555090ATrs9555090208002211.81E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105453695rs16965374CTrs16965374208002215.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13105486950rs1409470GArs1409470217507021.13E-04Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNA
13105807023rs16965962CArs16965962227605533.00E-07AA - GSENANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs16965962-T
13106450091rs4393432CTrs4393432208002218.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13106454877rs7998231GCrs7998231208002219.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13106460490rs3916978AGrs3916978208002219.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13106464102rs9519796GArs9519796208002219.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13106588826rs9519861CTrs9519861208002213.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13106612466rs1924397CArs1924397208002217.60E-06NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13106612466rs1924397CArs1924397232901967.60E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
13106642473rs2248399TCrs2248399229077300.0000139NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
13106642473rs2248399TCrs2248399229077300.0004141NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
13106643525rs1998560CTrs1998560229077300.000068NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
13106644450rs2248174AGrs2248174229077300.0000348NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
13106644450rs2248174AGrs2248174229077300.0003448NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at minimum 6 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
13107183056rs9520094TGrs9520094208002219.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13107769104rs9301191TCrs9301191208002217.08E-06NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13107771235rs9634463CTrs9634463208002215.74E-06NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13107772399rs713548GTrs713548208002215.93E-06NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13107773548rs7329003AGrs7329003208002215.80E-06NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13107780316rs1927745GArs1927745208002215.00E-06NA0.16[NA] unit decrease3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs1927745-AMeta-AnalysisResearch Support, N.I.H., Intramural
13107780316rs1927745GArs1927745232901964.70E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
13107784406rs9558953CGrs9558953208002213.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13108051084rs6492053TGrs6492053197363532.00E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
13108473323rs16971221TGrs16971221208002212.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13108564192rs7328941TCrs7328941224728766.64E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
13112136705rs1183183ACrs1183183216212694.71E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
13112854793rs7982118GCrs7982118224728764.77E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
13112983664rs7320500GArs7320500208002217.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
13113224567rs9324313AGrs9324313220599353.63E-04Sudden death suicides with a mood disorder vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
13113224567rs9324313AGrs9324313220599353.80E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
13113419191rs422046TCrs422046220471847.77E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
13113420269rs374433GCrs374433220471847.72E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
13114803885rs7995126GArs7995126208002212.52E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1421032624rs4982207CTrs4982207205161568.21E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
1424818907rs2144490CGrs2144490220471844.78E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1426291049rs1959778TCrs1959778224728765.49E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1426505853rs1015165CTrs1015165208002214.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1426599618rs17110779ACrs17110779210423172.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1426600297rs17110783AGrs17110783210423171.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1426610421rs17110793CTrs17110793210423171.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1426870128rs1474966GArs1474966197363534.60E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1426877020rs1474965AGrs1474965197363531.10E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1426884848rs1951387CArs1951387197363533.90E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1427149295rs962075TGrs962075224728762.91E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1427208456rs1956834TCrs1956834208002219.37E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1427212947rs12435132AGrs12435132208002218.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1427752103rs8017992GTrs8017992229077300.000142NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1427761190rs8020822AGrs8020822213168605.62E-06Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGNA
1427761335rs8020438CTrs8020438213168603.30E-06Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1431249816rs2106104AGrs2106104208002211.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1432341906rs9322878GArs9322878200389471.53E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1432408184rs1278918GArs1278918191071157.17E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1432841928rs17406568GArs17406568240474464.41E-05(Dichotomous)1.53NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
1433472423rs1953439GTrs1953439224728768.65E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1434744031rs17520436ATrs17520436224728762.77E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1435342238rs8011755TCrs8011755224728768.22E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1436649246rs944289CTrs944289229077300.0002207NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1437383879rs1367032AGrs1367032191071156.34E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGSLC25A21
1437387827rs17105696AGrs17105696191071157.85E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAASLC25A21
1437389830rs9635194CTrs9635194191071153.13E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACSLC25A21
1437391570rs861928AGrs861928191071151.24E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAASLC25A21
1437391907rs7150167GArs7150167191071158.28E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGSLC25A21
1437415923rs7145237AGrs7145237191071158.28E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAASLC25A21
1437671059rs4900700AGrs4900700220471848.38E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1442314553rs12895832TGrs12895832224728768.46E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1442321101rs17781474ATrs17781474224728767.34E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1442321934rs12884688CTrs12884688224728766.07E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1443188910rs1777077CTrs1777077217507021.70E-04Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNA
1444612482rs4906520CTrs4906520210423173.60E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1444618063rs8017211AGrs8017211210423173.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1447518437rs11624702CTrs11624702230914230.00000118NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1448296993rs17119161CTrs17119161208002213.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448340741rs1451928ACrs1451928208002217.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448344724rs4417486AGrs4417486208002217.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448349615rs8011411CTrs8011411208002217.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448352461rs17763705CTrs17763705208002215.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448353892rs8004167ACrs8004167208002213.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448354372rs8009188AGrs8009188208002213.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448355121rs10135568AGrs10135568208002213.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448355496rs8015225CTrs8015225208002213.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448357909rs1958334CTrs1958334208002213.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448386664rs2770417TArs2770417208002211.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448389312rs2480020TGrs2480020208002211.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448389981rs1952447CGrs1952447208002211.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448390700rs2683951CTrs2683951208002211.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448392457rs2770415CTrs2770415208002211.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448395224rs2683943TArs2683943208002211.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448397467rs2770411TGrs2770411208002211.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448399463rs2770407GCrs2770407208002211.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448400975rs1879520CTrs1879520208002211.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448401634rs2683942CGrs2683942208002211.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448406256rs2770402AGrs2770402208002211.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448417779rs1521166ATrs1521166208002212.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448418655rs1879519CG,Trs1879519208002212.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448419159rs2245010AGrs2245010208002219.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448425184rs1357041CTrs1357041208002213.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448431833rs2183087CArs2183087208002217.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448435689rs1357040GTrs1357040208002212.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448445047rs712429TCrs712429208002212.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448450084rs712435CTrs712435208002212.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448450886rs698298AGrs698298208002212.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448452592rs712437CGrs712437208002214.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1448466116rs810768GArs810768208002215.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1452079265rs1950926TGrs1950926208002217.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1453525427rs12882412CTrs12882412208002214.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1453531579rs2065345GArs2065345208002214.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1456818843rs12889725AGrs12889725210423177.80E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1457489712rs4901754GArs4901754232901969.62E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1458236413rs1950996GArs1950996229077300.0001423NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1458405679rs878085CTrs878085208002217.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1460146555rs1952043AGrs1952043191071151.09E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAARTN1
1460149910rs1013822GArs1013822191071154.26E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATRTN1
1461615710rs6573361CTrs6573361210423179.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1461619761rs724200CArs724200210423179.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1461936174rs8011286TArs8011286208002215.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1461938155rs4899049CTrs4899049208002218.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1463322347rs8012941AGrs8012941233776404.00E-06remission - SSRI treated - 12 weeks1.54[1.35-1.72] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs8012941-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1465197767rs229624GArs229624197363531.30E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1467232573rs10129827GArs10129827224728761.37E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1467263163rs8008773ATrs8008773232901967.48E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1467270123rs12587989AGrs12587989224728761.50E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1467453858rs8020095GArs8020095232901963.00E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs8020095-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1467461348rs7152001CGrs7152001232901963.08E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1467463012rs7142068CTrs7142068224728766.94E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1467849139rs2296561ATrs2296561232901966.22E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1467873128rs9323497CTrs9323497224728761.57E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1467888775rs8013144GArs8013144224728761.05E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1469050465rs2253168AGrs2253168210423172.80E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1469073826rs4902610CTrs4902610216212694.43E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1469073826rs4902610CTrs4902610pha0028502.99E-05phs0000201.28NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNANANA
1469928307rs1045301GTrs1045301232901963.94E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1469954376rs12050204GTrs12050204232901963.81E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1470334308rs10162497GArs10162497220471848.33E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1470338918rs2332172TGrs2332172220471843.25E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1474862010rs2190875CTrs2190875208002216.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1475349101rs8006560TCrs8006560224728762.37E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1477499459rs1106847TCrs1106847208002215.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1477788788rs8177544CTrs8177544200389474.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1477792053rs8004561CTrs8004561200389474.19E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1478608741rs10483891CTrs10483891208002216.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1480213080rs17764590GArs17764590224728769.93E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1481757197rs17550045CTrs17550045213168601.15E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACSTON2
1483882897rs7152555GArs7152555208002216.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1486197347rs8003655TCrs8003655191071154.43E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1488049175rs10146942TCrs10146942208002218.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488055411rs10137222ACrs10137222208002218.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488057863rs1887351TCrs1887351208002219.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488059134rs4517714CTrs4517714208002218.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488060316rs1952274AGrs1952274208002218.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488061751rs1958133CTrs1958133208002218.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488061930rs10220500GCrs10220500208002219.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488063050rs8013318TCrs8013318208002218.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488063092rs8012556GArs8012556208002218.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488063607rs1887349CTrs1887349208002218.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488065605rs1958132GA,C,Trs1958132208002219.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488069412rs17123606TGrs17123606208002217.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488071134rs980433CTrs980433208002217.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488076191rs10147942CTrs10147942208002217.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488076592rs7155892TCrs7155892208002217.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488080181rs11851496GArs11851496208002217.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488081186rs7492509CTrs7492509208002217.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488081876rs10130944GTrs10130944208002217.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488082002rs10145369TGrs10145369208002216.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488090264rs8006184GArs8006184208002215.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488092872rs7156776GArs7156776208002215.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488097901rs8006574CTrs8006574208002215.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488099099rs7154870GCrs7154870208002214.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488099985rs7149626CArs7149626208002215.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488101258rs1958129AGrs1958129208002214.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488104313rs8015320CArs8015320208002215.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488104600rs8015799CTrs8015799208002215.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488105892rs8022231GTrs8022231208002215.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488106258rs752146ATrs752146208002215.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488106865rs1075941GArs1075941208002214.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488107174rs10134221CTrs10134221208002215.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488107423rs10134597GArs10134597208002215.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1488108630rs8018749GArs8018749208002215.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1489995263rs373655AGrs373655220599352.02E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1489995263rs373655AGrs373655220599352.82E-04Sudden death suicides with a mood disorder vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1490148832rs8019799GArs8019799208002212.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1492190132rs1397164ACrs1397164232901963.08E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1493611243rs7150624TCrs7150624200389479.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1493611535rs7151193TGrs7151193200389476.38E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1495836056rs1187717CTrs1187717208002217.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1495931254rs4905326TCrs4905326208002212.01E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1495932223rs12434921AGrs12434921208002215.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1495934902rs8018925CGrs8018925208002211.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1496013584rs9323927AGrs9323927216212693.69E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1497618412rs7153003TCrs7153003229077300.0000911NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1498761519rs11621305ACrs11621305229077300.0001467NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1499747991rs2614461CTrs2614461224728762.68E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
14101525156rs4525426AGrs4525426210423178.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1523746396rs11638103ATrs11638103224728766.87E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1523747125rs4362366GTrs4362366224728766.61E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1523750690rs1608962CTrs1608962224728769.54E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1523752506rs9806254GArs9806254224728765.38E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1524082747rs17757180GArs17757180216212691.81E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
1524249141rs11630255TCrs11630255213168607.45E-06Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1524257659rs8026512TCrs8026512213168601.94E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1524257659rs8026512TCrs8026512213168606.04E-06Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1526025991rs8036650GArs8036650229077300.0001465NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1526766649rs4523899TCrs4523899224728761.00E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1526767183rs1365593AGrs1365593224728767.65E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1527391724rs208165TCrs208165224728763.24E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529517620rs12911875AGrs12911875208002214.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529518889rs1445490CTrs1445490208002212.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529519164rs8182074GCrs8182074208002218.50E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529519813rs767035AGrs767035208002212.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529521213rs11635026ACrs11635026208002212.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529521322rs11635074ATrs11635074208002212.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529523475rs4441240CTrs4441240208002212.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529523992rs17681991TCrs17681991208002211.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529525591rs12903523GArs12903523208002211.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529525855rs12912628TCrs12912628208002211.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529526279rs11071543CTrs11071543208002213.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529526921rs11634635TArs11634635208002212.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529527212rs11637568GCrs11637568208002212.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529528229rs12324268CTrs12324268208002212.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529528928rs12594866TGrs12594866208002212.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529529018rs12904918AGrs12904918208002212.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529530483rs12901764GArs12901764208002212.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529531333rs720644AGrs720644208002212.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529533378rs7175678CTrs7175678208002213.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1529692680rs1655645CTrs1655645229077300.0000662NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1529692680rs1655645CTrs1655645229077300.0000942NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1529704993rs1520936TCrs1520936229077300.0001994NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1529704993rs1520936TCrs1520936229077300.0002084NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1529905861rs2125657CTrs2125657232901963.62E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529905953rs2125659TCrs2125659232901963.21E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529906219rs2337127ACrs2337127232901963.95E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529906312rs7177816GArs7177816232901962.88E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529906544rs7182611GCrs7182611232901962.67E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529906749rs7182991GTrs7182991232901962.58E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529906788rs7170422TCrs7170422232901963.08E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529906878rs17750582CArs17750582232901963.25E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529914070rs4489949AGrs4489949232901962.74E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529915360rs8030855GCrs8030855232901962.43E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1529928780rs16955611AGrs16955611232901965.25E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1530193468rs711355TCrs711355229077300.0001745NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1531197564rs4779794GArs4779794213168601.03E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGFAN1
1531210651rs2293314AGrs2293314213168601.76E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAAFAN1
1531244083rs2955790TGrs2955790213168601.94E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAAMTMR10
1531251781rs2949574TCrs2949574213168601.04E-06Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATMTMR10
1533505067rs974379CArs974379233776408.00E-06% improvement - 2 weeks1.29[1.17-1.40] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs974379-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1533557850rs4780098TCrs4780098229077300.0001792NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1533877066rs659517GTrs659517191071158.83E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATRYR3
1533877585rs1495286GArs1495286191071153.73E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACRYR3
1533879387rs16972837GArs16972837191071158.27E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGRYR3
1536313965rs10520045GTrs10520045206738767.00E-06NA1.32[1.17-1.50] 597 German cases; 1,295 controlsNOPOP(1295)German(597)ALL(1892)NOPOP(1295)EUR(597)ALL(1892)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs10520045-TResearch Support, Non-U.S. Gov't
1538398000rs12324479GArs12324479210423173.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1538424060rs6495949TArs6495949210423177.40E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1538972177rs4924287AGrs4924287224728764.88E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1538977710rs7174485CArs7174485224728762.34E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1538986368rs12912251GTrs12912251224728763.57E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1538987380rs7496809GArs7496809224728761.37E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1538988097rs12903120GTrs12903120224728764.16E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1538990171rs2172835CTrs2172835224728762.97E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1538991520rs12916379AGrs12916379224728766.05E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1538992547rs2132157AGrs2132157224728768.67E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1538995491rs12899449AGrs12899449224728762.19E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1543028592rs7167392GArs7167392224728769.21E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1543039063rs7175582GArs7175582224728769.88E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1543202550rs9920182GArs9920182224728767.06E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1545447262rs1617207AGrs1617207208002213.64E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1547613403rs6493270TCrs6493270229077300.0000444NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1547613403rs6493270TCrs6493270229077300.0000558NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1547676489rs6493274ACrs6493274229077300.0001557NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1549192791rs8023445TCrs8023445190651449.00E-06Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1549192791rs8023445TCrs8023445200389475.42E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1549192791rs8023445TCrs8023445216212692.00E-06NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACSHC4
1549192791rs8023445TCrs8023445pha0028501.12E-05phs0000201.39NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACSHC4intronNM_203349
1549194041rs12441521AGrs12441521200389476.58E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1549198931rs12232276CTrs12232276200389477.52E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1549198978rs12232359TCrs12232359200389477.38E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1549939846rs8039808CA,G,Trs8039808220414585.00E-07Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers8039808-A
1550290295rs2413998AGrs2413998240474463.31E-05(Quantitative)1.19[NA] unit decrease1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs2413998-G
1551579598rs936306CTrs936306220599351.26E-04Sudden death suicides with a mood disorder vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1551579598rs936306CTrs936306220599354.13E-05Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1553169965rs7177989CTrs7177989232901967.26E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1553175197rs4776080TCrs4776080232901964.12E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1553184191rs2414188TCrs2414188232901967.80E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1553188169rs2414195GArs2414195232901962.98E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1553188893rs2414196GCrs2414196232901962.78E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1553189150rs8026763TCrs8026763232901963.30E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1553189424rs10851526TCrs10851526232901963.09E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1553239875rs12441046GTrs12441046232901964.65E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1553245436rs2414217TCrs2414217232901964.26E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1553246999rs2414218TCrs2414218232901964.13E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1554442615rs1864421CArs1864421208002213.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1554443986rs12902387TArs12902387208002213.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1554446522rs12916905ACrs12916905208002214.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1554446783rs12899222TGrs12899222208002216.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1554453774rs9788712CTrs9788712208002213.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1554455757rs12900128TCrs12900128208002213.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1554773440rs8038316GArs8038316232901969.64E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1554779611rs6493686CGrs6493686232901961.89E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1554780167rs8033074ACrs8033074232901961.90E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1557767982rs2922219GTrs2922219197363533.60E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1558804663rs12904012TCrs12904012208002218.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561141690rs341408TCrs341408191071151.02E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATRORA
1561210255rs8023563TArs8023563208002211.48E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561211189rs8028646ATrs8028646208002217.17E-06NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561211462rs8033151AGrs8033151208002213.10E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561211671rs11071568CTrs11071568208002214.96E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561212262rs2128166GArs2128166208002214.48E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561212974rs4264335AGrs4264335208002215.00E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561213564rs4775319GArs4775319208002216.11E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561213617rs4638513GArs4638513208002216.13E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561213991rs4547277GArs4547277208002216.16E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561214954rs1482051TCrs1482051208002212.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561219596rs12906588TGrs12906588208002214.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561267096rs12912233CTrs12912233208002216.00E-07NA0.15[NA] unit increase3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs12912233-TMeta-AnalysisResearch Support, N.I.H., Intramural
1561267096rs12912233CTrs12912233232901966.30E-07NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1561267752rs4775340GArs4775340208002216.27E-06NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561275513rs7175830GTrs7175830208002216.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561277083rs1949752GArs1949752208002217.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1561329788rs809736AGrs809736198460678.00E-06response1.52[1.27-1.83] Up to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tARORA
1562017105rs8028149CTrs8028149200389476.24E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1562859521rs8036087TGrs8036087208002219.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1562861409rs12908576CTrs12908576208002218.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1562864130rs12905414GArs12905414208002217.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1563299362rs902031TCrs902031197363531.40E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1566206204rs3803414GArs3803414217507023.40E-05Suicidal ideation and behaviour in major depressive disorder (SCAN Suicidality (SSU) score)NANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCMEGF11
1567089931rs12441020TGrs12441020208002219.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1568597127rs7174755TCrs7174755233776403.00E-07% improvement - SSRI treated - 2 weeks0.2[0.13-0.28] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs7174755-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1568597127rs7174755TCrs7174755233776409.00E-07% improvement - 2 weeks1.17[1.11-1.23] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs7174755-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1573011994rs17826791CGrs17826791198460677.72E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCBBS4
1574181538rs13638AGrs13638224728768.53E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1580255209rs2562754CTrs2562754220471842.78E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1581389238rs954969TGrs954969198460675.12E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNA
1584616332rs10520571AGrs10520571191071158.86E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATADAMTSL3
1584617077rs8028946CTrs8028946191071158.86E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACADAMTSL3
1585258203rs35524990TCrs35524990224728764.06E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1585285536rs17599989TCrs17599989224728763.40E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1585295927rs11637142AGrs11637142224728764.26E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1585298662rs12910012TCrs12910012224728763.81E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1585307287rs11633450CTrs11633450224728763.21E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1585328352rs3748376CTrs3748376224728765.19E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1586745924rs4887409TGrs4887409208002217.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1586806029rs1566088CTrs1566088230914230.00000483NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1586807077rs4887218GArs4887218230914230.0000044NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1586809025rs7181181TCrs7181181230914230.00000417NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1586809807rs8041327CTrs8041327230914230.00000434NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Serotonin reuptake inhibitors (SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1587087110rs11634524GArs11634524208002214.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1587436745rs17647114GArs17647114220414584.00E-07Citalopram+Bupropion, Vision/hearingNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers17647114-T
1588358250rs8030747TGrs8030747220471842.66E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1588359293rs11073742TArs11073742220471841.25E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1588361399rs11073745GArs11073745220471842.06E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1588493008rs8031871CTrs8031871220471846.37E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1588498141rs7170215ATrs7170215220471844.84E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1590211823rs894160CTrs894160208002216.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1590212144rs8179043TCrs8179043208002215.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1590329192rs6496603AGrs6496603pha0028501.26E-05phs0000201.25NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAANPEPintronNM_001150
1591812453rs6496780AGrs6496780216212694.84E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAASV2B
1593863467rs17541104CTrs17541104229077300.0000448NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1594755158rs958692GArs958692216212694.79E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1595827926rs4482230AGrs4482230197363533.20E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1596665128rs7178874ACrs7178874229077300.0002227NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1597205609rs7179934CTrs7179934216212695.50E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
1599073830rs6598518ACrs6598518230914230.00000379NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1599939263rs4965479CArs4965479224728768.62E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1599945673rs11247090CGrs11247090224728766.55E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1599945881rs4965480AGrs4965480224728764.19E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1599946006rs4965481GArs4965481224728762.57E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
15100055308rs1120716TArs1120716208002212.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
15100057431rs756143TArs756143208002219.63E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
15100299239rs6598266GArs6598266233776403.00E-06% improvement - SSRI treated - 12 weeks0.25[0.15-0.36] unit increaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs6598266-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
15100330051rs8027079TCrs8027079200389479.36E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
15100773215rs11857875TCrs11857875197363535.10E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
15101200284rs2956236GArs2956236229077300.0002037NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
15101869371rs752026AGrs752026208002219.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
15102097626rs4965898GTrs4965898210423172.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
15102101758rs8038697AGrs8038697210423171.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
15102101941rs9972548GArs9972548210423171.20E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
15102144955rs11634684CTrs11634684200389479.24E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
15102146151rs10152467AGrs10152467200389477.59E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
15102147426rs1020394TCrs1020394200389479.59E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
161313637rs11641981TCrs11641981224728764.31E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
161316225rs8045299AGrs8045299224728762.83E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
161320593rs9937841GArs9937841224728761.59E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
161997614rs2252523AGrs2252523229077300.0000549NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
161997614rs2252523AGrs2252523229077300.0002075NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
163992783rs11640300CTrs11640300224728761.60E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
163994696rs17256183TCrs17256183224728762.02E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
163999584rs2283491TCrs2283491210423176.00E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
164059746rs12921697CTrs12921697191071156.11E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACADCY9
165730176rs7205413GCrs7205413208002213.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
165731945rs4786751CGrs4786751208002214.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
165732416rs17138366CGrs17138366208002214.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
165732466rs17138369CTrs17138369208002214.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
165732697rs9929433ACrs9929433208002214.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
165735074rs8056887TCrs8056887208002219.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
165739204rs8063894GArs8063894208002219.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
165740007rs4786754GCrs4786754208002219.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
167065508rs1478727GArs1478727197363531.10E-06Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
167395292rs4257224TGrs4257224205161562.76E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyT
167980532rs6501039GArs6501039229077300.0000206NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
167986445rs6501041GArs6501041229077300.0001154NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
168024933rs6501049AGrs6501049229077300.0002147NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
168028614rs4786201GArs4786201229077300.0001996NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
168308675rs17145575GArs17145575224728763.50E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
168329327rs2034588TCrs2034588220414582.00E-06Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers2034588-G
1612434674rs16959252AGrs16959252208002218.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1613549769rs2188743GArs2188743191071155.27E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1613550540rs10852366CTrs10852366191071156.74E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1613656885rs2903308AGrs2903308227605532.00E-06EA + AA - Overall tolerabilityNANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs2903308-A
1614464656rs11075236CArs11075236210423173.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1624309956rs1557810CTrs1557810229153520.00000289NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<15HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTCACNG3
1625975588rs7199995CTrs7199995232901966.20E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1625975935rs7205464GTrs7205464232901963.75E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1625977007rs3922857CTrs3922857232901965.36E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1625977514rs4072224AGrs4072224232901967.05E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1625977900rs13339086GArs13339086232901966.99E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1625979718rs4297682AGrs4297682232901967.67E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1626741229rs716447TCrs716447224728767.29E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1627048236rs7206078CTrs7206078197363534.10E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1627134987rs9921605CTrs9921605224728769.83E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1629136331rs1642006GCrs1642006208002215.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629141436rs1646128GArs1646128208002218.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629147718rs1642025CGrs1642025208002216.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629154049rs1646112CTrs1646112208002211.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629156005rs166152AGrs166152208002211.27E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629164026rs252283CArs252283208002219.02E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629168052rs1364270AGrs1364270208002211.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629168094rs252289GTrs252289208002211.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629177452rs252358GCrs252358208002214.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629182179rs252353GArs252353208002217.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629184698rs252345TCrs252345208002211.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629192870rs252330CTrs252330208002211.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629215298rs153219GCrs153219208002211.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629224442rs252304GArs252304208002219.83E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629241389rs252246AGrs252246208002218.90E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629242488rs252247GCrs252247208002219.86E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629246102rs194045CTrs194045208002212.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629265186rs8050132CGrs8050132208002211.01E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1629265508rs11646318CArs11646318208002211.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1631364493rs4548893CTrs4548893229153520.000011NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tCNA
1652537526rs4784221AGrs4784221208002212.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652558834rs1420531GArs1420531208002213.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652570969rs11648477TCrs11648477208002213.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652597844rs4594251CTrs4594251208002215.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652603028rs3104751CTrs3104751208002211.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652603911rs3104753CTrs3104753208002211.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652605096rs3481AGrs3481208002211.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652606237rs3104755AGrs3104755208002211.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652608263rs3112562CGrs3112562208002211.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652612044rs1109951CTrs1109951208002212.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652612619rs3112638CTrs3112638208002212.00E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652613037rs12935019GArs12935019208002211.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652613581rs3104763AGrs3104763208002211.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652618113rs4784230TCrs4784230208002211.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652618953rs11645620CTrs11645620208002211.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652620577rs3112633CTrs3112633208002211.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652622112rs11640537GArs11640537208002211.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652623637rs6498960CTrs6498960208002215.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652623836rs4262942TGrs4262942208002215.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1652624446rs2335TGrs2335208002213.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1654057771rs17825567CArs17825567200389472.04E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1655118798rs13333707CTrs13333707216212698.87E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
1655253790rs2397376CTrs2397376240474464.08E-05(Quantitative)0.39[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs2397376-T
1657018102rs289744GTrs289744200389478.31E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1658697786rs8061077CTrs8061077217507021.80E-05Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCNA
1659310742rs6500030TGrs6500030191071156.86E-07NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
1659321826rs1117306AGrs1117306191071152.67E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAT,CNA
1659349532rs925338TCrs925338191071155.28E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
1659403054rs17186051GArs17186051191071154.09E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
1660406574rs1947261GArs1947261205161565.02E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
1661225355rs12930069GArs12930069208002219.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1661878581rs1369923CTrs1369923197363535.70E-06Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1662041227rs16964168GArs16964168208002214.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1663755083rs1451759GArs1451759210423178.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1666408031rs1076019GArs1076019229077300.0000917NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1666487206rs11646672ACrs11646672208002214.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1667271858rs3852700TCrs3852700210423173.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1669563842rs13330951AGrs13330951231494480.000076NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1672984340rs12149946GArs12149946220471841.27E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1672997747rs4788683GTrs4788683229077300.000219NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1673501536rs12446956TCrs12446956210423171.00E-06NA1.22NA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs12446956-CResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1673501536rs12446956TCrs12446956232901961.10E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1673785861rs328338CTrs328338191071156.78E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
1673804701rs16972539CTrs16972539217507021.56E-05Suicide attempts in major depressive disorderNANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCNA
1675019777rs17604707AGrs17604707220471842.37E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1677638665rs166826CG,Trs166826208002218.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1677668184rs3891920TCrs3891920208002218.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679307762rs4392087TCrs4392087208002219.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679308415rs8046680GArs8046680208002218.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679308531rs12596576CTrs12596576208002212.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679308897rs12924284CTrs12924284208002218.02E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679312083rs9806921CTrs9806921208002212.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679315897rs7194743TCrs7194743208002213.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679316298rs10871360AGrs10871360208002218.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679316318rs7193219GArs7193219208002215.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679316533rs4888945AGrs4888945208002215.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679316815rs8054578AGrs8054578208002212.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679317430rs4888946TArs4888946208002214.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679318712rs2347572GCrs2347572208002212.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679318983rs2881664TCrs2881664208002214.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679319300rs8056789ATrs8056789208002211.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679319687rs4888947CArs4888947208002214.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679336647rs1396702TCrs1396702208002212.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679336647rs1396702TCrs1396702pha0028506.06E-05phs0000201.46NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNANANA
1679346682rs17710897CTrs17710897208002216.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679361201rs1876763CTrs1876763208002213.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1679361953rs9939416GTrs9939416208002218.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1682303735rs2967319CTrs2967319208002216.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1682860249rs2549151GTrs2549151229077300.0000521NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1682860249rs2549151GTrs2549151229077300.0001008NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1682861814rs10492859AGrs10492859224728769.45E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1682902451rs11150506ACrs11150506216212698.76E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAACDH13
1683284338rs10514585GArs10514585208002215.00E-06NA0.15[NA] unit increase3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs10514585-AMeta-AnalysisResearch Support, N.I.H., Intramural
1683284338rs10514585GArs10514585232901964.90E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1683284554rs4782525TCrs4782525208002213.69E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683286768rs12596191GTrs12596191208002212.65E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683287432rs889724GArs889724208002214.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683288453rs748645CArs748645208002213.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683288987rs717840GArs717840208002212.43E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683290560rs1477418GCrs1477418208002212.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683293114rs12921178TCrs12921178208002212.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683295486rs8046875TGrs8046875208002213.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683295869rs7188467TC,Grs7188467208002212.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683319882rs17195894GArs17195894208002213.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683348255rs6563892AGrs6563892208002219.10E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683348824rs1035569AGrs1035569208002216.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683349398rs7194029TCrs7194029208002218.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683357284rs13336933CTrs13336933208002218.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683358776rs6563898AGrs6563898208002219.50E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683359653rs10514579CGrs10514579208002219.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683366609rs13332362AGrs13332362208002212.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683371484rs918771CTrs918771208002212.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683372034rs918767CGrs918767208002211.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683396737rs16960303AGrs16960303208002219.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1683418974rs889712GArs889712216212699.80E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAACDH13
1683487316rs8054845GArs8054845220599353.32E-04Sudden death suicides with a mood disorder vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1683487316rs8054845GArs8054845220599354.42E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1683492734rs1387381TCrs1387381220599351.15E-04Sudden death suicides with a mood disorder vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1683492734rs1387381TCrs1387381220599355.38E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1684786855rs7186789TGrs7186789208002216.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1686104142rs8050326GArs8050326238578903.00E-07NA1.45[1.26-1.76]805 European ancestry cases; 805 European ancestry controlsEuropean(1610)ALL(1610)EUR(1610)ALL(1610)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs8050326-AResearch Support, Non-U.S. Gov'tComparative StudyA
1686464336rs9929553ACrs9929553229153520.00000179NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset>25HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tANA
1687047185rs4552032TCrs4552032208002215.16E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1687048842rs8054887GArs8054887208002213.65E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1687461969rs9646303GArs9646303224728765.00E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1687481032rs12925472CTrs12925472224728769.65E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1687556088rs11645728AGrs11645728224728769.90E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1687680576rs12443771GArs12443771220471841.13E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1689703424rs445537AGrs445537197363534.00E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1689752194rs3751700GArs3751700224728766.37E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1689754255rs258324TGrs258324224728769.87E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1690024202rs8049897GArs8049897224728767.07E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
17961900rs2304961GArs2304961224728767.58E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
171220321rs7208333GTrs7208333208002214.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
171235037rs12937460GArs12937460208002216.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
171235317rs8076453ATrs8076453208002213.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
171235727rs11650217GArs11650217208002216.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
171281864rs10521111AGrs10521111208002215.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
171289749rs12938116CGrs12938116208002217.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
174722133rs3764900CTrs3764900224728762.46E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
175358671rs11867311CTrs11867311224728767.58E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
175361075rs3865353GTrs3865353224728761.05E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
175366650rs8070008CGrs8070008224728769.40E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
175381867rs3865350CTrs3865350224728761.17E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
175382031rs3865351CTrs3865351224728763.50E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
175391690rs2309399GArs2309399224728761.88E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
175396813rs9902174AGrs9902174224728767.18E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
176814546rs11656451TCrs11656451240474464.31E-05(Dichotomous)1.44NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs11656451-C
177569698rs8073498ACrs8073498229077300.0002086NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
178899137rs16957797TGrs16957797205161566.70E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyT
179148060rs2302198AGrs2302198208002217.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
179154655rs7219119CTrs7219119224728766.71E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1710168316rs12450499TCrs12450499229077300.0000336NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1710168316rs12450499TCrs12450499229077300.0001404NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1711224534rs12943640GArs12943640224728769.37E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1712318243rs8066012TCrs8066012224728766.30E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1712781955rs6502208GCrs6502208208002217.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1713633974rs17665827GArs17665827224728763.87E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1715421535rs12948266TCrs12948266217507026.00E-06Suicidal ideation and behaviour in major depressive disorder (SCAN Suicidality (SSU) score)NANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tT,CFAM18B2
1729019731rs7209032TCrs7209032191071158.95E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1731657608rs63953GArs63953220599358.50E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1731677160rs439783TCrs439783198460672.52E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGASIC2
1731866067rs9903859GArs9903859232901963.82E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731870759rs8079016CTrs8079016232901964.40E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731881235rs9898999CTrs9898999232901968.80E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731886384rs12452350AGrs12452350232901968.41E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731887161rs2043475CTrs2043475232901966.14E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731897097rs12453488GArs12453488232901962.02E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731900951rs12451111CTrs12451111232901967.72E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731901142rs12451588CGrs12451588232901968.98E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731903957rs12452510TArs12452510232901961.07E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731904005rs12449501GArs12449501232901961.24E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731907134rs12452091CGrs12452091232901967.07E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731911597rs8072065AGrs8072065232901966.10E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1731920154rs9900677AGrs9900677232901967.94E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1733772954rs7216096GArs7216096216212699.02E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGSLFN13
1733832591rs8077695TGrs8077695208002213.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1733840265rs8068906AGrs8068906208002215.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1733840295rs8068353CGrs8068353208002213.44E-06NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1733840328rs8067329GArs8067329208002214.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1733841044rs6505478CArs6505478208002215.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1733841737rs12450474CArs12450474208002212.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1733841737rs34006651CTCrs12450474208002212.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1733843512rs8070473TGrs8070473208002212.00E-06NA0.16[NA] unit decrease3,972 Sardinian individuals; 839 European ancestry individualsSardinian(3972)European(839)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionrs8070473-TMeta-AnalysisResearch Support, N.I.H., Intramural
1733843512rs8070473TGrs8070473232901961.50E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1733843917rs8066424CTrs8066424208002211.81E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1733846604rs4796093GArs4796093208002211.16E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1733847026rs2376179GArs2376179208002217.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1733847808rs7221507CTrs7221507208002219.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1735947226rs12942520GTrs12942520208002218.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1736173994rs1533494CTrs1533494208002219.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1738099035rs8065126TCrs8065126208002218.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1738111419rs1007655GArs1007655208002219.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1738111845rs2313640CTrs2313640208002219.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1738881219rs16966168GArs16966168232901961.31E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1738890734rs1073839TGrs1073839232901962.96E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1738891163rs9303295AGrs9303295232901964.09E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1740930095rs873084AGrs873084208002214.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1740971770rs9910698CTrs9910698208002211.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741176688rs2298862TCrs2298862208002216.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741179864rs915945CTrs915945208002218.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741188342rs9911630AGrs9911630208002218.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741191129rs11657053GTrs11657053208002217.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741195711rs8176323GCrs8176323208002217.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741195773rs8176322AGrs8176322208002217.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741197274rs8176318CArs8176318208002217.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741200109rs4793190TCrs4793190208002218.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741201702rs3092988CTrs3092988208002217.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741202688rs8070179GArs8070179208002217.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741203325rs8176297TArs8176297208002217.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741204377rs4793191AGrs4793191208002217.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741206056rs8176289TCrs8176289208002218.00E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741211653rs8176273AGrs8176273208002218.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741213996rs8176265CTrs8176265208002217.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741215825rs3092994CTrs3092994208002217.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741217874rs8176242CTrs8176242208002219.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741218333rs4793194GArs4793194208002219.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741223094rs1799966TA,C,Grs1799966208002219.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741223094rs397509198TTCrs1799966208002219.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741230228rs8176202GArs8176202208002219.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741231221rs8176194ACrs8176194208002219.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741231516rs8176193CTrs8176193208002219.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741231902rs4793197GArs4793197208002219.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741234470rs1060915AC,G,Trs1060915208002219.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741235799rs8067269GArs8067269208002219.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741237953rs3950989GArs3950989208002219.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741242285rs2070834TGrs2070834208002219.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741243190rs799916TGrs799916208002219.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741244000rs16942TCrs16942208002219.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741244435rs16941TA,C,Grs16941208002219.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741244435rs80357920TCTTTAATrs16941208002219.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741244936rs799917GA,C,Trs799917208002219.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741245237rs16940AGrs16940208002219.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741245237rs397508955AAG,ATGAAATACTGCTACTCTCTrs16940208002219.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741245466rs1799949GArs1799949208002219.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741251646rs8176140TArs8176140208002218.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741257134rs799912TCrs799912208002219.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741259049rs8176126CTrs8176126208002219.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741276247rs3765640AGrs3765640208002219.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741277187rs799905GCrs799905208002219.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741278116rs799906TCrs799906208002219.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741283377rs11653069CTrs11653069208002218.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741286822rs2175957TGrs2175957208002218.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741290613rs11656097GTrs11656097208002218.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741290674rs2292595GCrs2292595208002218.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741292739rs11658754GArs11658754208002218.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741297652rs7223062ACrs7223062208002218.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741300799rs11079056CArs11079056208002218.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741310495rs1973646TCrs1973646208002218.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741327621rs2271573AGrs2271573208002217.90E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741327648rs2271574TCrs2271574208002217.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741328095rs4239149AGrs4239149208002217.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741424101rs9646416CArs9646416208002217.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741433660rs4474733GTrs4474733208002216.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741442751rs11657004AGrs11657004208002217.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741444436rs11654307CGrs11654307208002217.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1741445145rs9912203GArs9912203208002217.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1742661960rs9944407CTrs9944407205161562.89E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
1742661960rs9944407CTrs9944407229153520.00000331NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<30HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCNA
1745889349rs12602461GArs12602461208002212.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1745953033rs9944405TArs9944405208002212.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1745965943rs4450442TGrs4450442208002212.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1745976389rs1133221TGrs1133221208002212.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1745982473rs16949270CTrs16949270208002212.26E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1745984949rs16949296AGrs16949296208002212.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746039543rs2525105GTrs2525105208002214.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746039553rs17616799AGrs17616799208002213.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746048412rs2285860GTrs2285860208002214.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746111172rs2240119TCrs2240119208002214.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746122270rs757353AGrs757353208002214.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746126373rs2023885GArs2023885208002213.49E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746136133rs2229369GCrs2229369208002213.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746142144rs2240120CTrs2240120208002213.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746152291rs16951519GArs16951519208002213.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746152322rs2240121TCrs2240121208002213.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746180664rs978263AGrs978263208002213.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746195335rs8071199TArs8071199208002213.31E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746203430rs7224461CGrs7224461208002213.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746207148rs2109983AGrs2109983208002219.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746210773rs3815472CTrs3815472208002213.32E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746217457rs8071879GArs8071879208002213.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746218545rs2325804GArs2325804208002213.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746229691rs208009CTrs208009208002213.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746230838rs208008CTrs208008208002215.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746239985rs208005AGrs208005208002213.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746293386rs1452663CGrs1452663208002212.44E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746296204rs16953941CArs16953941208002212.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746309546rs1979897CTrs1979897208002212.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746319546rs16954268GArs16954268208002212.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746324584rs16954324CTrs16954324208002214.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746328398rs17620866CGrs17620866208002212.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746334294rs17694092AGrs17694092208002212.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746348354rs17694404GArs17694404208002212.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746358952rs17621689TGrs17621689208002215.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746398352rs10514944GArs10514944208002215.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746430565rs17623416ACrs17623416208002215.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746438150rs17623518GArs17623518208002215.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746445993rs16955960TGrs16955960208002215.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746497274rs16956501GCrs16956501208002216.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746532956rs16957085GArs16957085208002214.87E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746535345rs9907565AGrs9907565208002215.07E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1746550362rs16957299GArs16957299208002216.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1748316872rs1881140AGrs1881140217507022.53E-05Suicidal ideation and behaviour in major depressive disorder (SCAN Suicidality (SSU) score)NANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCNA
1749224221rs2215290CTrs2215290213168607.58E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1750306841rs1875674TCrs1875674216212696.55E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1752297620rs11079111TCrs11079111191071154.33E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
1752315711rs12451623GArs12451623191071156.32E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
1752453585rs8066010GArs8066010205161562.77E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyG
1752467631rs8067196ACrs8067196205161562.26E-06NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
1752467631rs8067196ACrs8067196229153520.00000325NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<35HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tANA
1752467631rs8067196ACrs8067196229153520.00000376NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<30HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tANA
1752772651rs10468542AGrs10468542197363538.40E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1752780711rs10468512CTrs10468512197363536.60E-05Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1752925502rs4794538TCrs4794538240474463.47E-05(Quantitative)0.51[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs4794538-C
1753158361rs2628302GArs2628302213168607.14E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACSTXBP4
1754424871rs1547966CTrs1547966205161562.70E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
1755477138rs9904197CTrs9904197208002214.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1755485466rs11871646AGrs11871646208002212.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1756338778rs8178375TCrs8178375191071152.87E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATLPO
1756348230rs2071409TGrs2071409191071151.31E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAMPO
1756417287rs2014835TCrs2014835229077300.0001296NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1756421706rs1859401GArs1859401229077300.00024NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1756492800rs3744093TCrs3744093240474463.84E-05NA1.29NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs3744093-C
1756584205rs2302189ACrs2302189240474464.37E-05NA1.29NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs2302189-C
1757241938rs9892425GArs9892425208002219.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1760271972rs11654358CArs11654358224728768.18E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1760383604rs1913072CTrs1913072208002214.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1760389302rs1512444CArs1512444208002219.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1760410565rs12940211AGrs12940211208002218.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1760411708rs2080696TCrs2080696208002218.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1760413826rs12953094AGrs12953094208002216.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1760429710rs954563TCrs954563208002213.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1760789059rs9889540GCrs9889540208002214.52E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1760789316rs9890213GCrs9890213208002213.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1760789405rs9891713TCrs9891713208002215.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1761910167rs2584622GArs2584622216212697.92E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATSMARCD2
1764400808rs4417581TGrs4417581213168602.54E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACPRKCA
1764410915rs4790911TCrs4790911213168601.80E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGPRKCA
1764428682rs973753CTrs973753213168601.42E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATPRKCA
1766928815rs3744498CTrs3744498208002213.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1766928830rs3744499TCrs3744499208002213.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1766928920rs4147970CGrs4147970208002213.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1766929828rs4147968GArs4147968208002212.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1766943640rs4147953GArs4147953208002218.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1766943738rs4147951AGrs4147951208002218.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1767075072rs2302290GArs2302290208002219.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1767083139rs740517ACrs740517208002219.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1767089038rs2098034CTrs2098034208002216.82E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1767099129rs2364315AGrs2364315208002215.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1767109662rs11659091GArs11659091208002216.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1767665781rs6501341AGrs6501341208002217.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1772214863rs11658026ACrs11658026220471847.20E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1772523224rs10512596TCrs10512596220599354.73E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1776442641rs7211232CTrs7211232200389479.17E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1776633965rs4796827AGrs4796827240474462.00E-06NA1.33NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs4796827-A
1777804840rs9747992CTrs9747992245282842.00E-07(S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
1777804936rs9747031GCrs9747031245282846.13E-07(S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
1777856638rs4889796TCrs4889796232901965.83E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1778914748rs6420480GArs6420480208002216.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
18466351rs4797173CTrs4797173224728764.67E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
181923978rs1605930CTrs1605930208002213.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
181924923rs16942254GArs16942254208002217.04E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
182274078rs7236153TGrs7236153229077300.0002089NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
183316176rs1791124TGrs1791124224728766.93E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
183595765rs17647607AGrs17647607198460671.40E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tADLGAP1
183962377rs9946373TCrs9946373208002217.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
184448941rs280987CArs280987208002216.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
184449084rs280986GArs280986208002216.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
185250817rs8092448GTrs8092448208002213.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
185251192rs4798330TGrs4798330208002212.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
185286076rs1109434AGrs1109434208002211.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
185519322rs12965156CTrs12965156200389476.88E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
185555731rs1941000CTrs1941000200389479.49E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
185556111rs12955291CTrs12955291200389476.90E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
185556492rs12954752GCrs12954752200389477.75E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
186941108rs4398173AGrs4398173227605534.00E-06EA - Overall tolerabilityNANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs4398173-G
186941662rs3810046GTrs3810046227605535.00E-07EA + AA - Overall tolerabilityNANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs3810046-T
187383469rs4359528AGrs4359528210423176.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
187448196rs16951791GArs16951791240474462.97E-05(Quantitative)0.5[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs16951791-A
187592888rs1941137CTrs1941137216212697.37E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAPTPRM
187824091rs12963758TCrs12963758229077300.0000256NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
187824091rs12963758TCrs12963758229077300.0000444NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
189558525rs329020CTrs329020208002216.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
189583891rs329034CTrs329034208002216.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
189594877rs1275666GArs1275666208002216.88E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1810371035rs17541270AGrs17541270208002211.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1810385342rs206536TCrs206536208002219.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1810385479rs11080410TCrs11080410208002211.60E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1810385632rs11873516GArs11873516208002211.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1810385767rs11664110TCrs11664110208002211.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1810386324rs11661404ACrs11661404208002211.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1810386381rs11661411AGrs11661411208002211.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1810386714rs11661552CTrs11661552208002212.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1810923808rs264272GTrs264272233776403.00E-06% improvement - SSRI treated - 12 weeks0.17[0.099-0.243] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs264272-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1810923808rs264272GTrs264272233776404.00E-06% improvement - 12 weeks1.14[1.09-1.20] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs264272-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1812922549rs12326918GArs12326918240474463.33E-05NA1.38NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs12326918-A
1813247482rs4797752CTrs4797752208002219.29E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1813247880rs4797753TCrs4797753208002219.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1813255156rs9963094GTrs9963094208002219.24E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1820911592rs7233508TCrs7233508224728767.34E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1820913883rs6507592AGrs6507592224728766.26E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1820918419rs1276324CGrs1276324224728763.49E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1820921272rs1276321TCrs1276321224728764.45E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1820921272rs1276321TCrs1276321229153520.000011NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tGTMEM241
1820929994rs11082423TCrs11082423224728765.74E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1820930130rs7230499TCrs7230499224728766.31E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1820932722rs12456691CTrs12456691224728768.64E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1820935833rs17259202GTrs17259202224728768.80E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1820946796rs12607475CTrs12607475224728766.13E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1820946796rs12607475CTrs12607475229153520.00001NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tGTMEM241
1821502064rs3786412GArs3786412197363534.00E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1822330488rs9952222CArs9952222206198261.30E-06Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: self-rated)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
1822331765rs11873656ACrs11873656198460671.28E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
1822331765rs11873656ACrs11873656206198261.90E-06Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: self-rated)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
1822336276rs11872385TGrs11872385198460678.31E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tTNA
1822346141rs7229673CTrs7229673198460674.03E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
1822346141rs7229673CTrs7229673206198266.70E-06Citalopram response in major depressive disorder (Quick Inventory of Depressive Symptoms: self-rated)NANA1636 European ancestry samples; 264 Hispanic samples; 334 African ancestry samplesAfrican(334)European(1636)Hispanic(264)ALL(2234)AFR(334)HIS(264)EUR(1636)ALL(2234)Response to citalopram in major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepression
1822362861rs1451296TCrs1451296198460677.57E-06NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
1822365168rs6508329GArs6508329198460673.20E-06NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG,ANA
1822372891rs17203928GCrs17203928198460679.15E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNA
1822375671rs10502457CTrs10502457198460672.23E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
1822399548rs17203977CGrs17203977198460679.88E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
1822825993rs6508355AGrs6508355224728765.56E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1824973816rs7241931CTrs7241931220471846.38E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1824982471rs10164209CTrs10164209220471846.44E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1824988023rs8091214CTrs8091214220471846.44E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1824988282rs8091551CTrs8091551220471846.45E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1826120683rs17749815CTrs17749815229077300.0001297NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1826120683rs17749815CTrs17749815229077300.0002221NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1826163921rs11873775CTrs11873775229077300.0001265NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1826163921rs11873775CTrs11873775229077300.0001297NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1826176918rs8095062CArs8095062229077300.0001265NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1826176918rs8095062CArs8095062229077300.0001297NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1826194483rs16945051TCrs16945051229077300.0001265NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1826194483rs16945051TCrs16945051229077300.0001297NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1826196851rs7230370AGrs7230370229077300.0001265NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1826196851rs7230370AGrs7230370229077300.0001297NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1828638832rs1790695GArs1790695220599354.25E-05Sudden death suicides with a mood disorder vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1828638832rs1790695GArs1790695220599355.13E-04Sudden death suicides vs. controls who died from other causesNANA99 European ancestry subjectsEuropean(99)ALL(99)EUR(99)ALL(99)Suicide, with and without major depressionHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1829238357rs2595372CArs2595372229077300.0000507NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1829238357rs2595372CArs2595372229077300.0002128NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1831420010rs1013696TCrs1013696203603154.00E-06genotype x drug17.8NA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1831645379rs7239368GArs7239368198460679.00E-06remission1.45[1.22-1.69] Up to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNOL4
1832156187rs2849492TGrs2849492229077300.0002407NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1832175025rs6507096GArs6507096208002214.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1832238866rs10502626TCrs10502626208002219.91E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1832241897rs7227497GArs7227497208002218.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1832289448rs12963825AGrs12963825208002215.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1832574010rs11660848TCrs11660848208002216.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1832574960rs7240845GCrs7240845208002218.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1832575286rs531558TArs531558208002219.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1834119428rs1390431CTrs1390431200389479.71E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1835086774rs1786811TCrs1786811198460677.91E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGCELF4
1835087457rs1786776GArs1786776198460679.13E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tTCELF4
1836581023rs2958599TCrs2958599198460679.17E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
1838288514rs1436997TCrs1436997220471848.87E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1838300181rs8182398CTrs8182398220471843.49E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1838302138rs9950139TArs9950139220471842.57E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1838310763rs17749027GC,Trs17749027220471849.30E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1838324308rs9959057AGrs9959057220471847.53E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1838333985rs9963340TGrs9963340220471844.03E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
1839049013rs17710973TCrs17710973208002217.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1839068238rs7239339GArs7239339208002219.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1839069132rs12456335CTrs12456335208002215.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1839082090rs12607607CTrs12607607208002214.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1839084977rs12605092ATrs12605092208002214.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1839099218rs12606140CTrs12606140208002214.40E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1839102899rs11082237ATrs11082237208002216.59E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1839104470rs17712291TCrs17712291208002217.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1839121474rs12606897GArs12606897208002214.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1840156291rs9964460GArs9964460200389478.12E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1840161451rs7238529AGrs7238529200389477.90E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1840166871rs7228101AGrs7228101200389477.34E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1840766524rs12605134GTrs12605134208002218.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1840831637rs9955650CTrs9955650224728767.54E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1840862247rs16977454CArs16977454224728762.26E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1840872273rs12457996TCrs12457996210423176.00E-06NA1.15NA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs12457996-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1840872273rs12457996TCrs12457996224728761.21E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1840872273rs12457996TCrs12457996232901965.70E-06NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1843303089rs10460032AGrs10460032229077300.0000941NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1843303089rs10460032AGrs10460032229077300.0002378NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1843866158rs11873572TGrs11873572208002218.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1845887992rs6507842CArs6507842213168606.58E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1849063271rs7231303TCrs7231303229077300.0001201NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1849276222rs323105CGrs323105232901962.17E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1849279737rs12955929TGrs12955929232901963.28E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1849281080rs12955292GArs12955292232901964.44E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1849287112rs323097ACrs323097232901966.33E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1849288934rs9949310TCrs9949310232901967.02E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1850192001rs7242423GArs7242423231494480.00008NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1852780909rs4510110AGrs4510110210423175.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1852809403rs4800982GArs4800982210423172.70E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1852812241rs8099483TArs8099483210423172.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1852821124rs9951150AGrs9951150210423172.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1853133740rs2924328TCrs2924328224728764.49E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1853273614rs635538GArs635538224728769.60E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1854397622rs17750015TCrs17750015220641628.00E-06NA1.68[1.34-2.11] 467 European ancestry cases; 407 European ancestry controlsEuropean(874)ALL(874)EUR(874)ALL(874)Depression and alcohol dependenceHPOID:0000716DepressionDOID:303DOID:1596substance-related disordermental depressionD003863DepressionNANADepressionDrug abuseNA
1855197807rs7242048CTrs7242048208002214.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1855204476rs597741CTrs597741216212696.66E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
1856532820rs7226876CTrs7226876224728769.45E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1856668510rs7236560GArs7236560224728762.70E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1857314807rs11152166CTrs11152166238578903.00E-06NA1.41[1.22-1.61]805 European ancestry cases; 805 European ancestry controlsEuropean(1610)ALL(1610)EUR(1610)ALL(1610)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
1859282156rs1377169AGrs1377169200389478.38E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1859294347rs12454307TCrs12454307200389477.18E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1859586364rs6420563GArs6420563208002217.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1859660180rs651408GArs651408229077300.0001102NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1859836405rs4941117AGrs4941117229077300.0000858NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1859946568rs2980980AGrs2980980229077300.0001138NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1861265870rs9959343CTrs9959343232901961.77E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1861281648rs2168312GArs2168312232901961.47E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1861303978rs2077781GTrs2077781232901962.36E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1861306690rs2276203GArs2276203232901962.51E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1861322043rs4941210CTrs4941210232901962.92E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1861330572rs11664693GCrs11664693232901962.88E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1861339178rs1589595TCrs1589595232901963.66E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1861344012rs1011947GArs1011947232901963.36E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1861363389rs8091788GArs8091788232901968.14E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1861377579rs1395268ACrs1395268232901969.66E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1864071576rs4891441CArs4891441205161562.94E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
1865226341rs12607959CGrs12607959200389477.04E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1865242889rs1867413TCrs1867413200389475.54E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1865250728rs7504475GArs7504475200389479.54E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1865269343rs7236007TCrs7236007200389479.52E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1865285279rs17077540AGrs17077540200389477.49E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1865285279rs17077540AGrs17077540201250882.00E-07NA1.61NA1,020 European cases; 1,636 European controlsEuropean(2656)ALL(2656)EUR(2656)ALL(2656)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs17077540-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1865783629rs12961892AGrs12961892208002218.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1865800775rs9948101CTrs9948101208002217.46E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1865810472rs6566347AGrs6566347208002218.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1865810561rs8086608CTrs8086608208002217.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1865811182rs9950102CTrs9950102208002218.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1865811421rs4522509CTrs4522509208002218.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1865811548rs1518017CTrs1518017208002218.30E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1865811727rs1518018CTrs1518018208002217.39E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1865812483rs1607320GArs1607320208002219.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1866151075rs4891688CTrs4891688229077300.0001971NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1866315758rs627419TCrs627419200389473.85E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1868871013rs4439856GCrs4439856237266681.00E-04NA1.71[1.32-2.21]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionrs4439856-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1869116214rs2009217TCrs2009217197363531.30E-04Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
1869892744rs4430852CTrs4430852213168605.08E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANATNA
1869999553rs7245374TCrs7245374224728767.24E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1870974144rs4316844GArs4316844191071154.25E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
1871069742rs12969596CArs12969596200389473.91E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1871069901rs12970112GArs12970112200389474.33E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1871071196rs4508503GTrs4508503200389472.92E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1871071467rs883493GTrs883493200389473.81E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1871073486rs4243342TCrs4243342200389474.04E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1871073497rs4892099TGrs4892099200389475.06E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1871074051rs4614818TCrs4614818200389474.57E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1871074109rs4614819ATrs4614819200389472.17E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1871076103rs4528670GArs4528670200389478.59E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1871076298rs4627461TCrs4627461200389479.89E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1871077666rs9319871TCrs9319871200389479.09E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1871078121rs8087112TCrs8087112200389479.15E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1871078837rs9950597TCrs9950597200389478.55E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1872933187rs1866732AGrs1866732213168603.48E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGTSHZ1
1873378887rs2584466TCrs2584466216212698.89E-06NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
1874825768rs1629089CArs1629089200389477.85E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1874881660rs9966136TArs9966136208002216.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1875846089rs1472763GCrs1472763232901966.49E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1877321874rs7233804GArs7233804213168602.01E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
196689042rs11569523CTrs11569523220471844.44E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
196782052rs811292GArs811292200389479.85E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
196782498rs479660CTrs479660200389479.94E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
196782574rs568259CTrs568259200389478.89E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
196782701rs2546143GArs2546143200389472.26E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
196786271rs691528GArs691528200389479.74E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
196786503rs579371GArs579371200389479.72E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT,C
196788939rs659657TCrs659657200389479.08E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
196788979rs472835CTrs472835200389479.10E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
196791475rs2546124GArs2546124200389479.79E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
196792286rs2660485TCrs2660485200389477.91E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
196792315rs2546128AGrs2546128200389478.35E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
196792843rs2617809TCrs2617809200389478.77E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
196792868rs2546129AGrs2546129200389478.26E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
196793829rs2546131TCrs2546131200389477.02E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
196793918rs2546132GTrs2546132200389476.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
196794942rs2660487GArs2660487200389475.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
196795147rs2617815AGrs2617815200389475.43E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
196795389rs2617816AGrs2617816200389475.78E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
196795472rs4807900GArs4807900200389475.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
197832959rs8113469CTrs8113469216212696.77E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATCLEC4M
1911266693rs7251031TGrs7251031216212699.84E-06NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
1911358440rs2116877CTrs2116877210423172.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1913442039rs10426233CTrs10426233208002214.11E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1914827830rs3885179CArs3885179190651443.10E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1914827830rs3885179CArs3885179216212699.72E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGZNF333
1914827830rs3885179CArs3885179pha0028506.10E-05phs0000201.61NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGZNF333missenseNM_032433
1914940001rs8101893TCrs8101893217507023.41E-05Suicidal ideation and behaviour in major depressive disorder (SCAN Suicidality (SSU) score)NANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTNA
1915039616rs715158TGrs715158220471849.17E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1915045306rs7255992TArs7255992220471847.02E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1916676327rs10413178TCrs10413178232901967.14E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1917588762rs8109783GArs8109783203603153.06E-06NANANA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1917590281rs11666579GTrs11666579203603153.00E-06genotype x drug14.4NA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1918706504rs2283617GArs2283617200389471.43E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1918710535rs2238647GArs2238647200389478.20E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1918715203rs7249956CArs7249956200389478.11E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1919859845rs8104983AGrs8104983208002213.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1923065123rs7246529CTrs7246529220471848.54E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
1928383336rs12459082GArs12459082208002216.68E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928386386rs2215705TCrs2215705220471847.29E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
1928389129rs10516700TCrs10516700208002216.06E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928389609rs16968564CTrs16968564208002215.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928404607rs8102487ACrs8102487220471842.25E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralA
1928414086rs16968869GArs16968869208002217.01E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928422023rs16969007TGrs16969007208002216.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928424257rs16969062GTrs16969062208002216.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928424586rs7252365CGrs7252365208002211.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928424757rs17620671CTrs17620671208002217.74E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928424869rs7255713CGrs7255713208002211.69E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928445630rs12461645GArs12461645208002218.01E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928604705rs11669016GTrs11669016208002217.33E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928608226rs11671110TCrs11671110208002217.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928610147rs11084839CTrs11084839208002217.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928612739rs11667233CGrs11667233208002217.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928617530rs11672858CGrs11672858208002219.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1928619351rs11084844CTrs11084844208002218.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1929239439rs7257245TGrs7257245200389473.66E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1929263690rs12462886GTrs12462886200389471.73E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1929309594rs1473188TCrs1473188200389474.19E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1933089431rs17692896GArs17692896233776407.00E-07% improvement - SSRI treated - 2 weeks0.44[0.27-0.61] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs17692896-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1933711686rs10406787AGrs10406787191071156.30E-06NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGSLC7A10
1934020401rs33847TCrs33847229077300.0001794NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1934320854rs2546057ACrs2546057233776403.00E-07% improvement - 12 weeks1.18[1.12-1.24] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs2546057-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1934321258rs398426GTrs398426233776405.00E-06% improvement - SSRI treated - 12 weeks0.25[0.14-0.36] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs398426-TResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1934691449rs520194TCrs520194213168601.23E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACLSM14A
1935673243rs10426624ACrs10426624230914230.00000491NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1935673333rs10426076CTrs10426076230914230.00000476NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1936533195rs4806255ACrs4806255220471849.61E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC,T
1940176917rs16973566TCrs16973566198460678.30E-06NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
1946034558rs8111589CTrs8111589220641624.00E-06NA1.64[1.33-2.03] 467 European ancestry cases; 407 European ancestry controlsEuropean(874)ALL(874)EUR(874)ALL(874)Depression and alcohol dependenceHPOID:0000716DepressionDOID:303DOID:1596substance-related disordermental depressionD003863DepressionNANADepressionDrug abuseNA
1948357152rs4483956AGrs4483956229077300.0000906NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1949116555rs368654AGrs368654210423176.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949206172rs516246CTrs516246224728761.98E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949214748rs281381TCrs281381224728766.51E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949224484rs281393CTrs281393224728765.30E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949233406rs281408CArs281408224728761.61E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949241976rs973579AGrs973579224728761.73E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949244220rs2307019GArs2307019224728765.75E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949246866rs838147AGrs838147224728761.89E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949247693rs8108136CTrs8108136224728764.65E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949247786rs8108468GArs8108468224728764.94E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949247963rs8111399GTrs8111399224728765.06E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949248640rs12982115AGrs12982115224728765.48E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949249814rs8104897CArs8104897224728765.12E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949249888rs8105137GArs8105137224728764.89E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949250239rs838144CTrs838144224728762.07E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949250538rs11667321AGrs11667321224728762.86E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949442933rs2270939TCrs2270939210423174.90E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1949445817rs11666105TCrs11666105210423174.00E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1950230327rs8102150CGrs8102150245282847.00E-07(S-DCT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
1951549198rs2569469AGrs2569469229077300.000182NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1952863836rs2657940GArs2657940229077300.0001776NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1955680746rs7248997AGrs7248997213168602.76E-06Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANANANA
1955683104rs6509933TCrs6509933213168601.33E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
1955879872rs1126757CTrs1126757203603153.00E-06escitalopram10.4NA706 European descent individualsEuropean(706)ALL(706)EUR(706)ALL(706)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, Non-U.S. Gov't
1956178559rs310436TCrs310436208002218.45E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1956265664rs17634917AGrs17634917233776403.00E-06% improvement - 12 weeks1.37[1.23-1.51] Up to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs17634917-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1956265664rs17634917AGrs17634917233776406.00E-06% improvement - SSRI treated - 12 weeks0.38[0.21-0.54] unit decreaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs17634917-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1956572832rs10409555GArs10409555210423175.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1956897289rs8110950CGrs8110950208002213.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1957108783rs1035115TCrs1035115208002214.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1957113178rs3752183CTrs3752183229077300.0000354NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1957131436rs1035116CTrs1035116229077300.0000865NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1957421106rs4801190GArs4801190208002215.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1957421150rs4801191GArs4801191208002212.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
1957422295rs7259443CGrs7259443208002218.17E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
201995534rs6081597AGrs6081597200389474.53E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
202489419rs6049635TCrs6049635213168602.74E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACZNF343
203853551rs7272495GArs7272495208002215.53E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
203946057rs2300216AGrs2300216208002218.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
206009174rs1028410GArs1028410216212699.44E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGCRLS1
206018711rs2235816GArs2235816216212695.25E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGCRLS1
206454661rs6054292AGrs6054292213168607.84E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
208553750rs6055910AGrs6055910208002219.38E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
209919383rs2210455TGrs2210455205161563.70E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyT
2010113638rs1158389GCrs1158389216212696.94E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGLOC100131208
2010738950rs6104657AC,G,Trs6104657229153520.000017NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tANA
2010829979rs6040194GTrs6040194230914230.00000195NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2011157011rs6040399ATrs6040399227605531.00E-06AA - DizzinessNANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression casesNOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs6040399-T
2011157011rs6040399ATrs6040399227605537.00E-07EA + AA - DizzinessNANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs6040399-T
2011809442rs2423618TCrs2423618205161561.59E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyC
2011809442rs2423618TCrs2423618240474462.21E-05NA1.31NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs2423618-C
2011946072rs4814049ATrs4814049208002219.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2011946861rs6078410CTrs6078410208002218.98E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2013242166rs243903TCrs243903229077300.0001933NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2013907179rs6079225GCrs6079225210423173.90E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2013908548rs1321238CArs1321238210423173.50E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2013909450rs1884559GArs1884559210423177.70E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2013916402rs6042435ACrs6042435210423174.40E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2013924948rs1535190CGrs1535190210423177.40E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2013973760rs17226852TCrs17226852210423171.50E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2013974270rs8117766GArs8117766210423172.10E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2013987613rs8119080GArs8119080210423172.10E-06NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2013998098rs2263684GArs2263684210423174.80E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2014016348rs2257832GTrs2257832210423173.50E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2015446369rs6043298CTrs6043298208002217.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2015451179rs2180525GArs2180525208002215.16E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2015453539rs6034196CGrs6034196208002215.09E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2015454466rs6043303AGrs6043303208002214.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2015455186rs6043305AGrs6043305208002214.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2015455846rs6043308AGrs6043308208002214.95E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2015971797rs11700097GCrs11700097224728761.50E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2015981119rs1547117GArs1547117224728769.00E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2016448809rs6043973GArs6043973208002213.83E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2017683753rs6080790GArs6080790208002214.45E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2017703051rs2296902AGrs2296902208002213.51E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022427370rs2181063CGrs2181063208002218.78E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022430350rs6036116TCrs6036116208002218.81E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022436058rs6048104GArs6048104208002218.38E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022436129rs6048105TGrs6048105208002218.35E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022440480rs6036118GTrs6036118208002211.00E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022441124rs6036119TCrs6036119208002219.89E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022441181rs6036120TCrs6036120208002219.85E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022441952rs6048109GCrs6048109208002219.55E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022441996rs6048110GArs6048110208002216.55E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022445714rs6036127CTrs6036127208002219.52E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2022447954rs3935234GCrs3935234208002219.66E-05NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2024445155rs6114735AGrs6114735229077300.0002077NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2024546861rs8126241CTrs8126241208002217.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2024656927rs761440TCrs761440208002219.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2031398368rs437302GArs437302216212694.65E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
2031398368rs437302GArs437302pha0028506.98E-05phs0000201.37NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNANANA
2031585415rs190097TCrs190097220471844.95E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
2031585545rs440139CTrs440139220471844.44E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
2031586302rs4911280CArs4911280220471846.36E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
2031627291rs4911287AGrs4911287197363532.30E-06Antidepressant drug treatment outcome in depressionNANA339 German individualsGerman(339)ALL(339)EUR(339)ALL(339)Response to antidepressantsHPOID:0000716DepressionDOID:1596DOID:11718mental depressionantidepressant type abuseD003866Depressive Disorderresponse to antidepressantDepressionDrug abuseNAResearch Support, N.I.H., Extramural
2033547633rs6088662TGrs6088662224728766.13E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2033566722rs6088667TGrs6088667224728766.99E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2033592248rs752448CTrs752448224728765.17E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2033596876rs3818253GArs3818253224728764.70E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2033607551rs6088678CTrs6088678224728765.31E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2033623701rs6120804CArs6120804224728765.33E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2033633758rs6088691CTrs6088691224728766.11E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2038572414rs55734731CTrs55734731245282844.00E-07(S-CT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
2038576752rs62212409CGrs62212409245282844.12E-07(S-CT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
2038584590rs12479736AGrs12479736245282845.87E-07(S-CT concentration, adjusted for CYP2C19)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
2039536311rs6102209TCrs6102209229153520.00000192NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset>25HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tTNA
2040290806rs941796GArs941796190651443.70E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2040290806rs941796GArs941796216212695.21E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
2040290806rs941796GArs941796pha0028501.79E-05phs0000201.24NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
2040300232rs6016596AGrs6016596216212696.72E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
2040300232rs6016596AGrs6016596pha0028506.01E-05phs0000201.22NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNANANA
2040305351rs6129896AGrs6129896216212693.54E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
2040305932rs12480046CTrs12480046200389478.63E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2040307826rs12480143AGrs12480143190651443.50E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2040307826rs12480143AGrs12480143216212695.73E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNA
2040307826rs12480143AGrs12480143pha0028502.99E-05phs0000201.26NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGNANANA
2040309230rs17210039AGrs17210039216212693.73E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
2041286043rs2206426AGrs2206426216212699.97E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAPTPRT
2041286043rs2206426AGrs2206426pha0028509.22E-05phs0000201.2NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAAPTPRTintronNM_133170
2043734571rs6104012AGrs6104012229077300.0000591NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2043734571rs6104012AGrs6104012229077300.0001186NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2044885356rs2868715CTrs2868715208002218.36E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2044886189rs2868714GArs2868714208002218.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2044900733rs6065944CArs6065944208002219.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2044905385rs3904163GArs3904163208002219.85E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2044908527rs6032745TCrs6032745208002214.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2045191804rs202399AGrs202399200389473.90E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2045197192rs847068AGrs847068200389472.87E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2045199242rs440744CTrs440744200389473.99E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2045199417rs374564TCrs374564200389473.99E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2045199926rs863672CTrs863672200389474.00E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2045201501rs430891AGrs430891200389475.33E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2045202637rs2694877AGrs2694877200389473.94E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2045202771rs2694876GTrs2694876200389474.00E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2045203026rs381118TCrs381118200389473.93E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2045203100rs454302TCrs454302200389473.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2045203306rs412753AGrs412753200389473.97E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2045203360rs375578GTrs375578200389473.98E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2045203365rs454103TGrs454103200389474.02E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2045203421rs3091661CArs3091661200389474.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2045203442rs3092554GArs3092554200389474.08E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2045204535rs393990GTrs393990200389474.32E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2045204600rs399940CTrs399940200389474.11E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2045204763rs439143CArs439143200389474.09E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2045205138rs386843AGrs386843200389471.43E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2045205482rs413635CTrs413635200389472.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2045205891rs2745731ACrs2745731200389473.05E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA,C
2046093917rs4810643GArs4810643191071151.50E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
2046816900rs852335AGrs852335229077300.0001312NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2047647068rs3091529GArs3091529213168601.95E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAAARFGEF2
2047701339rs2075678AGrs2075678213168601.16E-05Cortisol secretion (cortisol AUC in females)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAACSE1L
2048974248rs13038647TCrs13038647200389475.16E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2050825149rs6063765CTrs6063765208002217.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050825358rs6063766CTrs6063766208002216.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050827159rs13043316CGrs13043316208002215.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050828285rs11697616GArs11697616208002214.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050839147rs6068102TCrs6068102208002213.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050843271rs998867GCrs998867208002213.63E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050843305rs2016367CGrs2016367208002216.58E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050846844rs6021796TCrs6021796208002215.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050853887rs6096824GArs6096824208002214.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050855171rs6126516CTrs6126516208002215.20E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050860315rs1998152AGrs1998152208002213.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050864670rs6013417TGrs6013417208002215.21E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050866193rs4809897GArs4809897208002213.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050872267rs6021819CTrs6021819208002215.73E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050873729rs6021820CTrs6021820208002215.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050878124rs2057078TCrs2057078208002215.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050878672rs13045010CTrs13045010208002214.56E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050878683rs2057079GCrs2057079208002215.94E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050879729rs6013423AGrs6013423208002215.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050880658rs6021824TArs6021824208002216.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050880949rs6013426CTrs6013426208002216.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050884797rs6096841GCrs6096841208002215.62E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050889596rs6021830CGrs6021830208002215.65E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050893173rs6021835GTrs6021835208002215.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050893858rs13040613GCrs13040613208002214.28E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050895335rs4809901CTrs4809901208002214.42E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050898577rs6068121AGrs6068121208002214.41E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050902254rs6068122ATrs6068122208002213.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050902910rs1016404AGrs1016404208002218.80E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050904777rs6068123CTrs6068123208002214.00E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050905406rs6091490CTrs6091490208002213.99E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050906010rs4811318GCrs4811318208002213.96E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2050907182rs6068124GArs6068124208002213.92E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2051236973rs8183283GArs8183283208002218.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2051245688rs1555185GArs1555185208002219.43E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2051560160rs731428TCrs731428232901968.53E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2054230997rs6024269TGrs6024269224728766.37E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2054231318rs1040697AGrs1040697224728767.67E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2055202984rs3827102TA,C,Grs3827102229153520.00000477NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tTNA
2055638750rs6127921ACrs6127921198460671.00E-06remission1.75[1.39-2.17] Up to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
2055638750rs6127921ACrs6127921198460673.00E-06response1.64[1.33-2.04] Up to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
2057111529rs6026339CGrs6026339208002217.03E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2057180009rs6026398AGrs6026398200389478.69E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2059067099rs90754GArs90754224728768.36E-05NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2059957189rs8121037TCrs8121037220471841.82E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralC
2060315878rs6061784TCrs6061784224728767.95E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2060317511rs7267604GArs7267604208002217.93E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2060338466rs1539470ACrs1539470210423174.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2061047465rs11204426AGrs11204426224728769.25E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2062218916rs13043255GCrs13043255224728762.72E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2062219740rs3810492GArs3810492224728762.20E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2062846531rs912239CTrs912239208002217.86E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2062852575rs168448ATrs168448208002211.18E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2062852930rs2015810CTrs2015810208002211.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2062856701rs2009307GArs2009307208002213.89E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2115474153rs2822404TCrs2822404208002218.19E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2115688269rs9975944CTrs9975944210423172.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2115692070rs2822567CTrs2822567210423174.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2115740108rs2822633TCrs2822633216212692.37E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANATNA
2116424469rs2823026CTrs2823026210423177.40E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2116431542rs2142219CTrs2142219210423176.10E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2121395574rs2825957TCrs2825957229077300.0001468NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2121637719rs928862AGrs928862190651444.00E-05Major depressive disorderNANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2121637719rs928862AGrs928862200389476.51E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2121637719rs928862AGrs928862216212692.06E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANA
2121637719rs928862AGrs928862pha0028503.77E-05phs0000201.3NANAALL(0)ALL(0)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAANANANA
2123145950rs2014791TCrs2014791200389478.46E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2125143119rs2828520GArs2828520201250884.00E-07NA1.35NA1,020 European cases; 1,636 European controlsEuropean(2656)ALL(2656)EUR(2656)ALL(2656)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs2828520-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2126567688rs2829621CGrs2829621208002218.22E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126572876rs2829629AGrs2829629208002215.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126575933rs2829634TCrs2829634208002215.79E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126577135rs2829636TCrs2829636208002214.76E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126577704rs2829638CTrs2829638208002214.78E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126584284rs1543772CArs1543772208002218.35E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126596313rs2829647TCrs2829647208002212.12E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126596637rs2829648TCrs2829648208002218.47E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126609246rs12626495CTrs12626495208002212.84E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126610323rs11087949GArs11087949208002216.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126612782rs11909262TCrs11909262208002214.72E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126622137rs2829660GArs2829660208002216.57E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126628258rs2829669CTrs2829669208002214.66E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126630543rs2829671CTrs2829671208002215.25E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2126636067rs2829675CTrs2829675208002214.64E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2127343288rs7283500TCrs7283500237266683.53E-05NA1.79[1.34-2.39]869 sustained response individuals; 247 unsustained response individualsNOPOP(1116)ALL(1116)NOPOP(1116)ALL(1116)Response to antidepressant treatment (citalopram)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionrs7283500-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2128665347rs2830840GCrs2830840198460675.00E-06remission1.47[1.23-1.72] Up to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tGNA
2128941967rs2831007TGrs2831007229077300.0000208NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2129582347rs2831649GArs2831649200389475.01E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2129647804rs2831689TCrs2831689229077300.0001611NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2131050817rs363512GArs363512230914230.0003NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with Norepinephrine reuptake inhibitors (NRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2132851853rs2833422ACrs2833422200389477.73E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2132852003rs2833423ATrs2833423200389474.53E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2132855150rs2833426TCrs2833426200389479.28E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2132856215rs7280029GCrs7280029200389478.85E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2132858220rs8131958CTrs8131958200389477.18E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2133018369rs9974610AGrs9974610200389476.16E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2133207694rs12482716CTrs12482716216212698.88E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACNA
2134485912rs13047973GArs13047973220471845.95E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralG
2136223627rs968625GArs968625191071151.59E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANAGRUNX1
2139206891rs2836007CTrs2836007232901969.68E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2139207740rs2211846GArs2211846232901966.08E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2139210521rs2836012TArs2836012232901966.21E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2139211005rs2836014CArs2836014232901966.48E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2139216353rs3787851CTrs3787851232901968.32E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2139217408rs2836021TCrs2836021232901965.59E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2139225737rs7276928GArs7276928229077300.0002455NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2139910680rs2836489CTrs2836489208002211.54E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141277049rs2244084AGrs2244084200389477.51E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2141284590rs9808736CTrs9808736208002211.15E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141715687rs11701859AGrs11701859208002212.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141727744rs16999692CTrs16999692208002212.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141730197rs11911007TCrs11911007208002212.71E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141733181rs16998067CArs16998067208002212.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141737909rs2837579TCrs2837579208002212.67E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141738635rs2837580AGrs2837580208002212.61E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141743639rs1980406TCrs1980406208002212.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141744294rs11911056CTrs11911056208002212.14E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141751640rs11910278TCrs11910278208002212.97E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141759666rs8132934ATrs8132934208002211.34E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141760168rs16999725ACrs16999725208002211.08E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2141824852rs1040315AGrs1040315240474465.07E-06(Dichotomous)1.48NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
2141886583rs9980603TCrs9980603240474463.00E-07(Dichotomous)1.53NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
2141910362rs2837693GArs2837693240474461.01E-05(Quantitative)0.63[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs2837693-A
2141910362rs2837693GArs2837693240474465.34E-06(Dichotomous)1.92NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs2837693-A
2141991059rs2837754GArs2837754229077300.0000372NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2141993707rs3804024TCrs3804024229077300.000081NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2142085920rs7276043TCrs7276043224728769.74E-06NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2143997911rs435725AGrs435725198460678.18E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tASLC37A1
2144003992rs449888AGrs449888198460672.80E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tANA
2144006207rs408465CTrs408465198460677.06E-06NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
2144026143rs11701162CArs11701162198460671.81E-05NANANAUp to 883 responders; 608 non-respondersNOPOP(1491)ALL(1491)NOPOP(1491)ALL(1491)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tCNA
2144125328rs2245730ACrs2245730230914230.0009NANANA1790 individualsNOPOP(1790)ALL(1790)NOPOP(1790)ALL(1790)Change in depression severity with antidepressants (NRI or SRI)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2144362904rs8130292GTrs8130292229077300.0001063NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2145151874rs9974754GArs9974754240474461.82E-05(Quantitative)0.44[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs9974754-A
2145687581rs2838540AGrs2838540229077300.000137NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2217649774rs5748926TCrs5748926224728763.05E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2223646953rs131686TArs131686224728761.80E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2223648009rs131690GArs131690224728761.84E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2223649242rs131693TGrs131693224728762.14E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2225095452rs915611CArs915611213168608.09E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAANA
2226306095rs2331193ATrs2331193208002214.04E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2226313745rs5761313GTrs5761313208002217.77E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2229904519rs2283859TCrs2283859229077300.0000399NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2229904519rs2283859TCrs2283859229077300.0001655NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2229983138rs16987839GArs16987839229077300.0000793NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
2231011882rs4820021ATrs4820021200389478.97E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
2233001276rs16990831GArs16990831200389475.18E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2233561994rs5994683GCrs5994683200389479.04E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2233565885rs10483170CGrs10483170200389472.28E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
2233568560rs2213457GTrs2213457200389475.66E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
2233706143rs8138316CTrs8138316191071154.36E-05NANANA1,359 cases; 1,782 controlsNOPOP(3141)ALL(3141)NOPOP(3141)ALL(3141)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACLARGE
2234224916rs2267298CArs2267298213168603.16E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAALARGE
2234422094rs242888GArs242888220471848.74E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
2234424170rs129315TGrs129315220471848.74E-05Serum brain derived neurotrophic factor concentrationNANA2054 Italian subjectsItalian(2054)ALL(2054)EUR(2054)ALL(2054)Brain derived neurotrophic factor levels, in serumHPOID:0000716DepressionDOID:1596mental depressionNANANANADepressionNAMeta-AnalysisResearch Support, N.I.H., IntramuralT
2234823828rs1034394AGrs1034394233776402.00E-06% improvement - SSRI treated - 12 weeks0.21[0.12-0.3] unit increaseUp to 2,256 European ancestry casesEuropean(2256)ALL(2256)EUR(2256)ALL(2256)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionrs1034394-GResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2236074043rs5755867TCrs5755867210423172.30E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2237529724rs3218315GArs3218315208002219.13E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2237532665rs228954TCrs228954208002219.75E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2237533786rs228957CGrs228957208002214.23E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2237534034rs2284033GArs2284033208002216.05E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2237535948rs228963AGrs228963208002219.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2237535948rs397960003AAGrs228963208002219.48E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2237537514rs228966TCrs228966208002219.55E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2237661288rs5750402CArs5750402210423173.90E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2237666786rs4820279CTrs4820279210423174.60E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2237799369rs5756670AGrs5756670231494480.0000136NANANA4346 cases; 4430 controlsNOPOP(8776)ALL(8776)NOPOP(8776)ALL(8776)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2237982012rs12157904ACrs12157904220414582.00E-06Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers12157904-G
2242392811rs1062753GArs1062753245282842.00E-16(S-DDCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
2242392811rs1062753GArs1062753245282847.99E-16(S-DDCT/S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
2242523528rs1058172CTrs1058172245282847.99E-16(S-DDCT/S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
2242523528rs1058172CTrs1058172245282848.00E-16(S-DDCT/S-DCT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
2242526694rs1065852GArs1065852245282842.00E-16(S-DDCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
2242526694rs1065852GArs1065852245282847.99E-16(S-DDCT/S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
2242526694rs1065852GArs1065852245282848.00E-16(S-DDCT/S-DCT ratio)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
2242536263rs1058174GArs1058174245282847.99E-16(S-DDCT/S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
2242619067rs1033459AGrs1033459245282847.99E-16(S-DDCT/S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
2242619308rs1033460AGrs1033460245282847.99E-16(S-DDCT/S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralA
2242670111rs1001587CTrs1001587245282847.99E-16(S-DDCT/S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralG
2242670293rs1001586GTrs1001586245282847.99E-16(S-DDCT/S-DCT concentration)NANA300 European ancestry Escitalpram treated individuals; 130 European ancestry Citalopram treated individualsEuropean(430)ALL(430)EUR(430)ALL(430)Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAClinical TrialResearch Support, N.I.H., ExtramuralC
2243745197rs715001CArs715001208002218.81E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2244204319rs8140172CTrs8140172210423174.10E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2244390366rs2235779AGrs2235779208002213.70E-04NANANA3,972 Italian individuals; 839 European ancestry individualsEuropean(839)Italian(3972)ALL(4811)EUR(4811)ALL(4811)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAMeta-AnalysisResearch Support, N.I.H., Intramural
2244626164rs139263AGrs139263232901967.13E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2244628068rs139265GArs139265232901965.15E-05NANANAup to 34,549 European ancestry individualsEuropean(34549)ALL(34549)EUR(34549)ALL(34549)Depression (quantitative trait)HPOID:0000716DepressionDOID:1596mental depressionD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
2245302662rs1894524GArs1894524213168605.30E-05Cortisol secretion (cortisol AUC)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANAGPHF21B
2245525484rs9306489AGrs9306489205161562.34E-05NANANA1,636 UK cases; 1,594 UK controlsUK(3230)ALL(3230)EUR(3230)ALL(3230)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, Non-U.S. Gov'tComparative StudyA
2248394746rs10483240CTrs10483240240474463.94E-05NA1.5NA1,080 European ancestry cases; 1,588 European ancestry controlsEuropean(2668)ALL(2668)EUR(2668)ALL(2668)Anxiety and major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs10483240-T
2248500387rs5767024CTrs5767024224728762.79E-04NANANA9,240 European ancestry cases; 9,519 European ancestry controlsEuropean(18759)ALL(18759)EUR(18759)ALL(18759)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
X5972382rs1882411CTrs1882411217507023.35E-05Suicidal ideation and behaviour in major depressive disorder (SCAN Suicidality (SSU) score)NANA2023 European ancestry individuals with major depressive disorderEuropean(2023)ALL(2023)EUR(2023)ALL(2023)Major depression (suicidal thoughts and behavior)HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tCNLGN4X
X6702509rs6638625GArs6638625229153520.00000134NANANAUp to 2,746 European ancestry cases; 1,584 European ancestry controlsEuropean(4330)ALL(4330)EUR(4330)ALL(4330)Major depressive disorder age at onset<20HPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, Non-U.S. Gov'tGNA
X8407329rs10521594CArs10521594190651445.40E-05Major depressive disorder (males)NANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X9295882rs5934574TCrs5934574240474464.25E-05(Dichotomous)1.49NA1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderNA
X12890453rs1731479CTrs1731479229077300.0002418NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X22982459rs4618863TCrs4618863190651445.00E-04Major depressive disorder (females)NANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X23382666rs5971108GCrs5971108190651443.00E-04Major depressive disorder (females)NANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X23382666rs5971108GCrs5971108216212694.37E-05NANANA1,726 cases; 1,630 controlsNOPOP(3356)ALL(3356)NOPOP(3356)ALL(3356)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNANACPTCHD1
X32015376rs16990008AGrs16990008220414582.00E-06Citalopram+Buspirone, DizzinessNANA1,439 non-psychotic major depressive disorder casesNOPOP(1439)ALL(1439)NOPOP(1439)ALL(1439)Response to antidepressant treatmentHPOID:0000716DepressionDOID:11718DOID:1596antidepressant type abusemental depressionD003866Depressive DisorderNANADepressionDrug abusers16990008-C
X32213962rs921896TCrs921896240474464.00E-06(Quantitative)0.47[NA] unit increase1,080 European ancestry cases; 442 European ancestry controlsEuropean(1522)ALL(1522)EUR(1522)ALL(1522)Anxiety in major depressive disorderHPOID:0000716DepressionDOID:1470DOID:2030major depressive disorderanxiety disorderNANANANADepressionGeneralized anxiety disorderrs921896-C
X32396824rs2207796GTrs2207796190651445.00E-04Major depressive disorder (females)NANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X32454346rs2405829AGrs2405829200389473.82E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
X32456711rs2076366GCrs2076366200389472.13E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
X33315969rs3946125GTrs3946125210423173.80E-04NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
X45671994rs5905484CTrs5905484229077300.0001482NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X45681372rs5905485GTrs5905485229077300.000187NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X45685205rs2206355GArs2206355229077300.0002232NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X45698719rs7058787CTrs7058787229077300.0000244NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X45698719rs7058787CTrs7058787229077300.0002108NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X66676395rs6625187CTrs6625187229077300.0000813NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X82871195rs5922838AGrs5922838220641625.00E-06NA2.17[1.55-3.02] 467 European ancestry cases; 407 European ancestry controlsEuropean(874)ALL(874)EUR(874)ALL(874)Depression and alcohol dependenceHPOID:0000716DepressionDOID:303DOID:1596substance-related disordermental depressionD003863DepressionNANADepressionDrug abuseNA
X82954490rs5968205CTrs5968205220641623.00E-06NA2.2[1.58-3.07] 467 European ancestry cases; 407 European ancestry controlsEuropean(874)ALL(874)EUR(874)ALL(874)Depression and alcohol dependenceHPOID:0000716DepressionDOID:303DOID:1596substance-related disordermental depressionD003863DepressionNANADepressionDrug abuseNA
X86686922rs6617370GArs6617370229077300.000102NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
X86697958rs4322150CTrs4322150229077300.000102NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X86705153rs6624058GArs6624058229077300.0000827NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
X95060007rs5949649CTrs5949649200389471.08E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X95060938rs5990409GTrs5990409200389471.03E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
X95061014rs5990410GArs5990410200389471.72E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
X95063723rs5949650CArs5949650200389471.09E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X95068770rs5949654TCrs5949654200389477.48E-06NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X95070824rs12216984TCrs12216984200389471.21E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X95070973rs7064559GArs7064559200389471.22E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
X95072450rs5990415CTrs5990415200389471.36E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X95073188rs5949327TCrs5949327200389471.27E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X95073929rs5990145TCrs5990145200389471.26E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X95074041rs7062843TCrs7062843200389471.26E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X95074253rs2031597TCrs2031597200389471.26E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X95074863rs5949657GArs5949657200389471.23E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
X95075156rs5949658TCrs5949658200389471.14E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X95076190rs11798245TArs11798245200389473.12E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X95079870rs5990417TCrs5990417200389476.00E-06NA1.23NA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionrs5990417-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X95280329rs1408095GArs1408095213168605.46E-05Cortisol secretion (cortisol AUC in males)NANA1711 European individualsEuropean(1711)ALL(1711)EUR(1711)ALL(1711)Cortisol secretion, in salivaHPOID:0011731Abnormality of circulating cortisol levelDOID:1596mental depressionNANANANADepressionNANACNA
X116222263rs6646773AGrs6646773227605531.00E-06EA + AA - GSENANA1,392 European ancestry depression cases; 264 African American depression cases; 106 depression cases NOPOP(106)African American(264)European(1392)ALL(1762)NOPOP(106)AFR(264)EUR(1392)ALL(1762)Response to citalopram treatmentHPOID:0000716DepressionDOID:1470major depressive disorderD015283Citalopramresponse to antidepressantDepressionrs6646773-C
X117314176rs2539952GArs2539952229077300.0002191NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
X117314383rs2539953CTrs2539953229077300.0002191NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X117317618rs2802919TGrs2802919229077300.0001544NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X120316909rs17282946GArs17282946210423174.00E-05NANANA2,431 European ancestry cases; 3,673 European ancestry controlsEuropean(6104)ALL(6104)EUR(6104)ALL(6104)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
X122316437rs3761555TCrs3761555229077300.0000516NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
X125957843rs12854061CTrs12854061200389474.95E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X125960729rs12557112GArs12557112200389473.68E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA,G
X125961388rs12835281TCrs12835281200389473.84E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X125963245rs5931716AGrs5931716200389473.34E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
X125964007rs5931717CTrs5931717200389473.28E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X125965102rs5930036CTrs5930036200389472.88E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X125969026rs4573418AGrs4573418200389473.18E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
X125970041rs3131422AGrs3131422200389474.08E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
X125972757rs4458996TCrs4458996200389473.07E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X125977849rs12556725GArs12556725200389473.13E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
X125978876rs5930039AGrs5930039200389473.15E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
X125981732rs3131364GArs3131364200389474.08E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X125990345rs3131358GArs3131358200389474.15E-05NANANA3,957 cases; 3,428 controlsNOPOP(7385)ALL(7385)NOPOP(7385)ALL(7385)Major depressive disorder (broad)HPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderNANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X134066599rs5930667CTrs5930667190651444.00E-04Major depressive disorder (females)NANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
X141270430rs5908216AGrs5908216229077300.0002224NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
X141270735rs5954560GArs5954560229077300.0001656NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - remission at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
X145639678rs996435TCrs996435229077300.0002222NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
X145643498rs5966262AGrs5966262229077300.0001131NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at last visitHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
X145643498rs5966262AGrs5966262229077300.000154NANANAUp to 499 European ancestry casesEuropean(499)ALL(499)EUR(499)ALL(499)Treatment outcomes for selective serotonin reuptake inhibitors (SSRIs) - response at 8 weeksHPOID:0000716DepressionDOID:1470major depressive disorderNANANANADepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
X146040013rs11094388AGrs11094388190651443.00E-04Major depressive disorder (females)NANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
X147852561rs5936428GArs5936428190651449.00E-04Major depressive disorder (females)NANA1738 Western European ancestry cases; 1802 Western European ancestry controlsWestern European(3540)ALL(3540)EUR(3540)ALL(3540)Major depressive disorderHPOID:0000716DepressionDOID:1470major depressive disorderD003866Depressive DisorderEFOID:0003761unipolar depressionDepressionNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
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