PedAM
Pediatric Disease Annotations & Medicines
| meige syndrome | ||||
| Disease ID | 1555 |
|---|---|
| Disease | meige syndrome |
| Definition | A syndrome characterized by orofacial DYSTONIA; including BLEPHAROSPASM; forceful jaw opening; lip retraction; platysma muscle spasm; and tongue protrusion. It primarily affects older adults, with an incidence peak in the seventh decade of life. (From Adams et al., Principles of Neurology, 6th ed, p108) |
| Synonym | blepharospasm - oromandibular dystonia blepharospasm oromandibular dyskinesia blepharospasm oromandibular dystonia blepharospasm oromandibular dystonia syndrome blepharospasm oromandibular dystonia syndrome, idiopathic blepharospasm-oromandibular dyskinesia blepharospasm-oromandibular dyskinesias blepharospasm-oromandibular dystonia blepharospasm-oromandibular dystonia syndrome blepharospasm-oromandibular dystonia syndrome, idiopathic blepharospasm-oromandibular dystonia syndromes blepharospasm-oromandibular dystonias brueghel syndrome dyskinesia, blepharospasm-oromandibular dyskinesia, idiopathic orofacial dyskinesias, blepharospasm-oromandibular dyskinesias, idiopathic orofacial dystonia syndrome, blepharospasm-oromandibular dystonia syndromes, blepharospasm-oromandibular dystonia, blepharospasm-oromandibular dystonias, blepharospasm-oromandibular idiopathic blepharospasm oromandibular dystonia syndrome idiopathic blepharospasm-oromandibular dystonia syndrome idiopathic orofacial dyskinesia idiopathic orofacial dyskinesias meige syndrome (disorder) meige syndrome [disease/finding] meige's syndrome meiges syndrome orofacial dyskinesia, idiopathic orofacial dyskinesias, idiopathic syndrome, blepharospasm-oromandibular dystonia |
| Orphanet | |
| DOID | |
| UMLS | C0025183 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:3) |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:15) 10343 | PKDREJ | DISEASES 55145 | THAP1 | DISEASES 5805 | PTS | DISEASES 1816 | DRD5 | DISEASES 2303 | FOXC2 | DISEASES 54345 | SOX18 | DISEASES 1861 | TOR1A | DISEASES 2736 | GLI2 | DISEASES 57165 | GJC2 | DISEASES 3356 | HTR2A | DISEASES 2296 | FOXC1 | DISEASES 4287 | ATXN3 | DISEASES 2643 | GCH1 | DISEASES 820 | CAMP | DISEASES 102723508 | KANTR | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1555 |
|---|---|
| Disease | meige syndrome |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:5) HP:0100753 | Schizophrenia | 2 HP:0012049 | Spasmodic dysphonia | 1 HP:0100315 | Lewy bodies | 1 HP:0001332 | Dystonia | 1 HP:0001618 | Dysphonia | 1 |
| Disease ID | 1555 |
|---|---|
| Disease | meige syndrome |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:5) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0025183 | chlorpromazine | D002746 | 50-53-3 | meige syndrome | MESH:D008538 | marker/mechanism | 2887231 | ||
| C0025183 | fluvoxamine | D016666 | 54739-18-3 | meige syndrome | MESH:D008538 | marker/mechanism | 18081639 | ||
| C0025183 | haloperidol | D006220 | 52-86-8 | meige syndrome | MESH:D008538 | marker/mechanism | 2894781 | ||
| C0025183 | sulpiride | D013469 | 15676-16-1 | meige syndrome | MESH:D008538 | marker/mechanism | 12163987 | ||
| C0025183 | tetrabenazine | D013747 | 58-46-8 | meige syndrome | MESH:D008538 | therapeutic | 3279337 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |