PedAM
Pediatric Disease Annotations & Medicines
| malaria | ||||
| Disease ID | 38 |
|---|---|
| Disease | malaria |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:107) C2712323 | hypoglycaemia C2711227 | hepatic steatosis C2707258 | infections C2364133 | infection C2364072 | depression C2203646 | jaundice C2186740 | urticaria C2096315 | headache C1963164 | lymphopenia C1963154 | renal failure C1963091 | diarrhea C1962966 | retinopathy C1839611 | n syndrome C1801950 | g syndrome C1548477 | dengue fever C1393529 | vascular complications C1384353 | infestation C1373218 | immunosuppression C1264047 | abdominal lymphadenopathy C1263988 | hemolytic disease C1096155 | macrophage activation syndrome C1000483 | anemia C0876991 | hemophagocytosis C0856169 | endothelial dysfunction C0752303 | urological manifestations C0748159 | pulmonary involvement C0745153 | hypoglycemic episodes C0743841 | febrile illness C0702094 | agranulocytosis C0687720 | central diabetes insipidus C0679466 | cognitive deficits C0679225 | multiple pathologies C0424755 | fever C0422833 | ent symptoms C0341697 | renal impairment C0275524 | mixed infection C0271930 | anemia in pregnancy C0271711 | spontaneous hypoglycaemia C0267373 | intestinal bleeding C0262471 | ent problem C0242723 | parasitemia C0242584 | autoimmune thrombocytopenia C0242567 | opsoclonus C0240066 | iron deficiency C0235031 | neurologic symptoms C0221505 | cerebral lesions C0162429 | malnutrition C0162316 | iron deficiency anemia C0155305 | optic nerve ischemia C0151740 | intracranial hypertension C0085650 | purpura fulminans C0041349 | tubulointerstitial nephritis C0041296 | tuberculosis C0040188 | tic disorders C0040034 | thrombocytopenia C0039730 | thalassemia C0039730 | thalassaemias C0039128 | syphilis C0038826 | superinfection C0036572 | seizures C0036396 | sciatica C0035222 | adult respiratory distress syndrome C0035222 | acute respiratory distress syndrome C0035021 | recurrent fever C0034063 | pulmonary edema C0033774 | pruritus C0033117 | priapism C0031069 | periodic fever C0027873 | neuromyelitis optica C0027726 | nephrotic syndrome C0027697 | nephritides C0024530 | plasmodium infection C0024291 | hemophagocytic syndrome C0023501 | leukemoid reaction C0022660 | acute renal failure C0022658 | renal disorders C0022658 | renal disease C0022658 | nephropathy C0022658 | nephropathies C0022658 | kidney disorders C0021051 | immunodeficiency C0020649 | hypotension C0020615 | hypoglycemia C0020598 | hypocalcemia C0020532 | hypersplenism C0020455 | hypergammaglobulinaemia C0019209 | hepatomegaly C0019080 | hemorrhage C0017920 | glucose-6-phosphate dehydrogenase deficiency C0016085 | filariasis C0014544 | epilepsy C0014038 | encephalitis C0013395 | indigestion C0013369 | dysentery C0011991 | diarrhoea C0007760 | cerebellar syndrome C0007758 | cerebellar ataxia C0007222 | cardiovascular diseases C0006625 | cachexia C0006413 | burkitt's lymphoma C0006035 | borreliosis C0005779 | coagulopathy C0004610 | bacteremia C0002878 | haemolytic anaemia C0002871 | anemias C0002871 | anaemia C0001125 | lactic acidosis |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:54) C0009450 | infection | 306 C0015967 | fever | 120 C0021311 | infections | 100 C0002871 | anaemia | 71 C0002871 | anemia | 60 C0242723 | parasitemia | 38 C0743841 | febrile illness | 31 C0040034 | thrombocytopenia | 18 C0275524 | mixed infection | 16 C0036572 | seizures | 15 C0041296 | tuberculosis | 12 C0035078 | renal failure | 10 C0035309 | retinopathy | 9 C0022346 | jaundice | 9 C0021079 | immunosuppression | 8 C0004610 | bacteremia | 7 C0022660 | acute renal failure | 6 C0162316 | iron deficiency | 5 C0039730 | thalassemia | 5 C0162429 | malnutrition | 5 C0752303 | urological manifestations | 5 C0021051 | immunodeficiency | 4 C0002878 | haemolytic anaemia | 3 C0020649 | hypotension | 3 C0024530 | plasmodium infection | 3 C0011991 | diarrhoea | 3 C0018681 | headache | 3 C0035222 | acute respiratory distress syndrome | 3 C0038826 | superinfection | 3 C0020598 | hypoglycaemia | 2 C0042109 | urticaria | 2 C0040188 | tic disorders | 2 C0020598 | hypoglycemia | 2 C0014544 | epilepsy | 2 C0011991 | diarrhea | 2 C0039128 | syphilis | 2 C0019080 | hemorrhage | 2 C0019209 | hepatomegaly | 2 C0162316 | iron deficiency anemia | 2 C0422833 | ent symptoms | 2 C0341697 | renal impairment | 1 C0856169 | endothelial dysfunction | 1 C0015974 | periodic fever | 1 C0014038 | encephalitis | 1 C0037280 | infestation | 1 C1839611 | n syndrome | 1 C0017920 | glucose-6-phosphate dehydrogenase deficiency | 1 C0034063 | pulmonary edema | 1 C0013395 | indigestion | 1 C0005779 | coagulopathy | 1 C0876991 | hemophagocytosis | 1 C0022658 | nephropathy | 1 C0006413 | burkitt's lymphoma | 1 C0001125 | lactic acidosis | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:90) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs10900585 | 22895189 | 493 | ATP2B4 | umls:C0024530 | GWASCAT | One of the loci was identified on chromosome 1q32 within the ATP2B4 gene, which encodes the main calcium pump of erythrocytes, the host cells of the pathogenic stage of malaria parasites. | 0.120542884 | 2012 | ATP2B4 | 1 | 203684896 | G | T |
| rs11036238 | 19465909 | 283111 | OR51V1 | umls:C0024530 | GAD | [Genome-wide and fine-resolution association analysis of malaria in West Africa.] | 0.002367032 | 2009 | NA | 11 | 5204405 | G | C |
| rs11036238 | 19465909 | 3043 | HBB | umls:C0024530 | GAD | [Genome-wide and fine-resolution association analysis of malaria in West Africa.] | 0.019912403 | 2009 | NA | 11 | 5204405 | G | C |
| rs11091253 | 23297791 | 6778 | STAT6 | umls:C0024530 | BeFree | The study indicated that the STAT6 promoter polymorphism rs3024944 was associated with uncomplicated malaria, whereas the FOXP3 promoter variant rs11091253 was associated with significant P. falciparum parasitaemia levels. | 0.000271442 | 2013 | FOXP3 | X | 49265564 | G | A |
| rs1126535 | 26448013 | 3552 | IL1A | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.001085767 | 2016 | CD40LG | X | 136648396 | T | C |
| rs1126535 | 26448013 | 959 | CD40LG | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.004810009 | 2016 | CD40LG | X | 136648396 | T | C |
| rs1126535 | 26448013 | 7124 | TNF | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.157314477 | 2016 | CD40LG | X | 136648396 | T | C |
| rs1126535 | 26448013 | 3565 | IL4 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.009977336 | 2016 | CD40LG | X | 136648396 | T | C |
| rs1126535 | 26448013 | 55692 | LUC7L | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.000271442 | 2016 | CD40LG | X | 136648396 | T | C |
| rs1126535 | 26448013 | 4843 | NOS2 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.139445464 | 2016 | CD40LG | X | 136648396 | T | C |
| rs1211375 | 26448013 | 7124 | TNF | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.157314477 | 2016 | LUC7L | 16 | 190281 | A | C |
| rs1211375 | 26448013 | 4843 | NOS2 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.139445464 | 2016 | LUC7L | 16 | 190281 | A | C |
| rs1211375 | 26448013 | 3565 | IL4 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.009977336 | 2016 | LUC7L | 16 | 190281 | A | C |
| rs1211375 | 26448013 | 3552 | IL1A | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.001085767 | 2016 | LUC7L | 16 | 190281 | A | C |
| rs1211375 | 26448013 | 959 | CD40LG | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.004810009 | 2016 | LUC7L | 16 | 190281 | A | C |
| rs1211375 | 26448013 | 55692 | LUC7L | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.000271442 | 2016 | LUC7L | 16 | 190281 | A | C |
| rs12212067 | 24035192 | 2309 | FOXO3 | umls:C0024530 | BeFree | We identify a noncoding polymorphism in FOXO3A (rs12212067: T > G) at which the minor (G) allele, despite not being associated with disease susceptibility, is associated with a milder course of Crohn's disease and rheumatoid arthritis and with increased risk of severe malaria. | 0.000814326 | 2013 | FOXO3 | 6 | 108659993 | T | G |
| rs12788102 | 23717212 | 256892 | OR51F1 | umls:C0024530 | GWASCAT | Imputation-based meta-analysis of severe malaria in three African populations. | 0.12 | 2013 | OR51F1 | 11 | 4769345 | A | G |
| rs1451375 | 19465909 | 1644 | DDC | umls:C0024530 | GAD | [Genome-wide and fine-resolution association analysis of malaria in West Africa.] | 0.002638474 | 2009 | DDC | 7 | 50555014 | C | A |
| rs1695 | 19635899 | 2950 | GSTP1 | umls:C0024530 | BeFree | However, a significant association of GSTP1 I105V genotype with severe malarial anemia was discovered (26.0% against 10.3% mild malaria, P = 0.004). | 0.000814326 | 2009 | GSTP1 | 11 | 67585218 | A | G |
| rs17561 | 26448013 | 3552 | IL1A | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.001085767 | 2016 | IL1A | 2 | 112779646 | C | A |
| rs17561 | 26448013 | 3565 | IL4 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.009977336 | 2016 | IL1A | 2 | 112779646 | C | A |
| rs17561 | 26448013 | 7124 | TNF | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.157314477 | 2016 | IL1A | 2 | 112779646 | C | A |
| rs17561 | 26448013 | 55692 | LUC7L | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.000271442 | 2016 | IL1A | 2 | 112779646 | C | A |
| rs17561 | 26448013 | 959 | CD40LG | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.004810009 | 2016 | IL1A | 2 | 112779646 | C | A |
| rs17561 | 26448013 | 4843 | NOS2 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.139445464 | 2016 | IL1A | 2 | 112779646 | C | A |
| rs1800750 | 26448013 | 4843 | NOS2 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.139445464 | 2016 | TNF | 6 | 31575186 | G | A |
| rs1800750 | 26448013 | 55692 | LUC7L | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.000271442 | 2016 | TNF | 6 | 31575186 | G | A |
| rs1800750 | 26448013 | 3552 | IL1A | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.001085767 | 2016 | TNF | 6 | 31575186 | G | A |
| rs1800750 | 26448013 | 7124 | TNF | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.157314477 | 2016 | TNF | 6 | 31575186 | G | A |
| rs1800750 | 26448013 | 959 | CD40LG | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.004810009 | 2016 | TNF | 6 | 31575186 | G | A |
| rs1800750 | 26448013 | 3565 | IL4 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.009977336 | 2016 | TNF | 6 | 31575186 | G | A |
| rs1800925 | 19840389 | 3596 | IL13 | umls:C0024530 | BeFree | Only rs1881457 located in the promoter region of IL13, which is in linkage disequilibrium with rs1800925 (r2 = 0.73), showed a significant association with severe malaria after adjusting for multiple testing (P = 0.046 by permutation test). | 0.001357209 | 2009 | IL13;LOC101927761 | 5 | 132657117 | C | T |
| rs1805015 | 26448013 | 959 | CD40LG | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.004810009 | 2016 | IL4R | 16 | 27362859 | T | C |
| rs1805015 | 26448013 | 3565 | IL4 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.009977336 | 2016 | IL4R | 16 | 27362859 | T | C |
| rs1805015 | 26448013 | 3552 | IL1A | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.001085767 | 2016 | IL4R | 16 | 27362859 | T | C |
| rs1805015 | 26448013 | 4843 | NOS2 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.139445464 | 2016 | IL4R | 16 | 27362859 | T | C |
| rs1805015 | 26448013 | 7124 | TNF | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.157314477 | 2016 | IL4R | 16 | 27362859 | T | C |
| rs1805015 | 26448013 | 55692 | LUC7L | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.000271442 | 2016 | IL4R | 16 | 27362859 | T | C |
| rs1881457 | 19840389 | 3596 | IL13 | umls:C0024530 | BeFree | Only rs1881457 located in the promoter region of IL13, which is in linkage disequilibrium with rs1800925 (r2 = 0.73), showed a significant association with severe malaria after adjusting for multiple testing (P = 0.046 by permutation test). | 0.001357209 | 2009 | IL13;LOC101927761 | 5 | 132656717 | A | C |
| rs2069705 | 25445652 | 770 | CA11 | umls:C0024530 | BeFree | The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)). | 0.000271442 | 2014 | IFNG | 12 | 68161231 | G | A |
| rs2069718 | 25445652 | 770 | CA11 | umls:C0024530 | BeFree | The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)). | 0.000271442 | 2014 | IFNG | 12 | 68156382 | A | G |
| rs2069727 | 25445652 | 770 | CA11 | umls:C0024530 | BeFree | The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)). | 0.000271442 | 2014 | IFNG | 12 | 68154443 | T | C |
| rs2069728 | 25445652 | 770 | CA11 | umls:C0024530 | BeFree | The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)). | 0.000271442 | 2014 | NA | 12 | 68154004 | C | T |
| rs2243250 | 26448013 | 3552 | IL1A | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.001085767 | 2016 | IL4 | 5 | 132673462 | C | T |
| rs2243250 | 26448013 | 7124 | TNF | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.157314477 | 2016 | IL4 | 5 | 132673462 | C | T |
| rs2243250 | 26448013 | 3565 | IL4 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.009977336 | 2016 | IL4 | 5 | 132673462 | C | T |
| rs2243250 | 26448013 | 4843 | NOS2 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.139445464 | 2016 | IL4 | 5 | 132673462 | C | T |
| rs2243250 | 26448013 | 959 | CD40LG | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.004810009 | 2016 | IL4 | 5 | 132673462 | C | T |
| rs2243250 | 26448013 | 55692 | LUC7L | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.000271442 | 2016 | IL4 | 5 | 132673462 | C | T |
| rs2274567 | 25683978 | 1378 | CR1 | umls:C0024530 | BeFree | These findings suggest that CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T polymorphisms may not be involved in susceptibility to malaria in Chinese population. | 0.124267125 | 2015 | CR1 | 1 | 207580276 | A | G |
| rs2296160 | 25683978 | 1378 | CR1 | umls:C0024530 | BeFree | These findings suggest that CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T polymorphisms may not be involved in susceptibility to malaria in Chinese population. | 0.124267125 | 2015 | CR1 | 1 | 207621975 | A | G |
| rs2430561 | 25445652 | 770 | CA11 | umls:C0024530 | BeFree | The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)). | 0.000271442 | 2014 | IFNG | 12 | 68158742 | T | A |
| rs3024944 | 23297791 | 6778 | STAT6 | umls:C0024530 | BeFree | The study indicated that the STAT6 promoter polymorphism rs3024944 was associated with uncomplicated malaria, whereas the FOXP3 promoter variant rs11091253 was associated with significant P. falciparum parasitaemia levels. | 0.000271442 | 2013 | STAT6 | 12 | 57111665 | C | G |
| rs3138557 | 25445652 | 770 | CA11 | umls:C0024530 | BeFree | The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)). | 0.000271442 | 2014 | NA | NA | NA | NA | NA |
| rs334 | 24312262 | 132014 | IL17RE | umls:C0024530 | BeFree | Furthermore, IL17RE rs708567 GA and hHbS rs334 AT individuals were associated with protection from uncomplicated malaria and anaemia respectively in this study. | 0.000271442 | 2013 | HBB | 11 | 5227002 | T | G,C,A |
| rs386502799 | 19602285 | 114609 | TIRAP | umls:C0024530 | BeFree | Low frequency of the TIRAP S180L polymorphism in Africa, and its potential role in malaria, sepsis, and leprosy. | 0.120814326 | 2009 | NA | NA | NA | NA | NA |
| rs386547285 | 21457584 | 54106 | TLR9 | umls:C0024530 | BeFree | The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods. | 0.012539865 | 2011 | NA | NA | NA | NA | NA |
| rs386547285 | 21457584 | 7099 | TLR4 | umls:C0024530 | BeFree | The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods. | 0.015892975 | 2011 | NA | NA | NA | NA | NA |
| rs3918242 | 26013370 | 4318 | MMP9 | umls:C0024530 | BeFree | Matrix metalloproteinase-9 polymorphism 1562 C > T (rs3918242) associated with protection against placental malaria. | 0.000542884 | 2015 | MMP9 | 20 | 46007337 | C | T |
| rs414171 | 20484391 | 1154 | CISH | umls:C0024530 | GAD | [When all five single-nucleotide polymorphisms (SNPs) (at positions -639, -292, -163, +1320, and +3415 all relative to CISH) within the CISH-associated locus were considered together in a multiple-SNP score, we found an association between CISH genetic variants and susceptibility to bacteremia, malaria, and tuberculosis (P=3.8x10(-11) for all comparisons), with -292 accounting for most of the association signal (P=4.58x10(-7)).] | 0.122367032 | 2010 | CISH;MAPKAPK3 | 3 | 50612068 | A | T |
| rs4833095 | 20478407 | 7096 | TLR1 | umls:C0024530 | BeFree | The toll-like receptor 1 variant S248N influences placental malaria. | 0.002909916 | 2010 | TLR1 | 4 | 38798089 | T | C |
| rs4844600 | 25683978 | 1378 | CR1 | umls:C0024530 | BeFree | These findings suggest that CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T polymorphisms may not be involved in susceptibility to malaria in Chinese population. | 0.124267125 | 2015 | CR1 | 1 | 207505962 | A | C,G |
| rs4986790 | 21457584 | 7099 | TLR4 | umls:C0024530 | BeFree | The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods. | 0.015892975 | 2011 | TLR4 | 9 | 117713024 | A | G |
| rs4986790 | 21457584 | 54106 | TLR9 | umls:C0024530 | BeFree | The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods. | 0.012539865 | 2011 | TLR4 | 9 | 117713024 | A | G |
| rs4986791 | 21457584 | 54106 | TLR9 | umls:C0024530 | BeFree | The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods. | 0.012539865 | 2011 | TLR4 | 9 | 117713324 | C | T |
| rs4986791 | 21457584 | 7099 | TLR4 | umls:C0024530 | BeFree | The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods. | 0.015892975 | 2011 | TLR4 | 9 | 117713324 | C | T |
| rs5030738 | 23935200 | 2209 | FCGR1A | umls:C0024530 | BeFree | Fc gamma receptor 3B (FCGR3B-c.233C>A-rs5030738) polymorphism modifies the protective effect of malaria specific antibodies in Ghanaian children. | 0.001628651 | 2014 | FCGR3B | 1 | 161629864 | G | T |
| rs5030738 | 23935200 | 2215 | FCGR3B | umls:C0024530 | BeFree | Fc gamma receptor 3B (FCGR3B-c.233C>A-rs5030738) polymorphism modifies the protective effect of malaria specific antibodies in Ghanaian children. | 0.007915422 | 2014 | FCGR3B | 1 | 161629864 | G | T |
| rs5498 | 19055786 | 3383 | ICAM1 | umls:C0024530 | BeFree | Association of the ICAM1 rs5498 (exon 6) G allele and the CD36 exon 1a A allele with increased risk of severe malaria was observed (severe versus control, OR = 1.91 and 2.66, P = 0.02 and 0.0012, respectively). | 0.134525834 | 2008 | ICAM1;ICAM4;LOC105372272 | 19 | 10285007 | A | G |
| rs5498 | 19055786 | 948 | CD36 | umls:C0024530 | BeFree | Association of the ICAM1 rs5498 (exon 6) G allele and the CD36 exon 1a A allele with increased risk of severe malaria was observed (severe versus control, OR = 1.91 and 2.66, P = 0.02 and 0.0012, respectively). | 0.133973019 | 2008 | ICAM1;ICAM4;LOC105372272 | 19 | 10285007 | A | G |
| rs5743836 | 21457584 | 54106 | TLR9 | umls:C0024530 | BeFree | The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods. | 0.012539865 | 2011 | TLR9 | 3 | 52226766 | A | G |
| rs5743836 | 21457584 | 7099 | TLR4 | umls:C0024530 | BeFree | The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods. | 0.015892975 | 2011 | TLR9 | 3 | 52226766 | A | G |
| rs6503319 | 19465909 | 4621 | MYH3 | umls:C0024530 | GAD | [Genome-wide and fine-resolution association analysis of malaria in West Africa.] | 0.002367032 | 2009 | MYH3 | 17 | 10670842 | C | T |
| rs6503319 | 19465909 | 6341 | SCO1 | umls:C0024530 | GAD | [Genome-wide and fine-resolution association analysis of malaria in West Africa.] | 0.002367032 | 2009 | MYH3 | 17 | 10670842 | C | T |
| rs668 | 19055786 | 5175 | PECAM1 | umls:C0024530 | BeFree | Interestingly, a SNP of the PECAM1 gene (rs668, exon 3, C/G) with low minor allele frequency in populations of the endemic region compared to the non-endemic region exhibited differential association with disease in these regions; the G allele was a risk factor for malaria in the endemic region, but exhibited significant association with protection from disease in the non-endemic region. | 0.003181358 | 2008 | NA | NA | NA | NA | NA |
| rs6755404 | 23717212 | 91752 | ZNF804A | umls:C0024530 | GWASCAT | Imputation-based meta-analysis of severe malaria in three African populations. | 0.12 | 2013 | ZNF804A | 2 | 184932501 | A | C |
| rs708567 | 24312262 | 132014 | IL17RE | umls:C0024530 | BeFree | Furthermore, IL17RE rs708567 GA and hHbS rs334 AT individuals were associated with protection from uncomplicated malaria and anaemia respectively in this study. | 0.000271442 | 2013 | IL17RC | 3 | 9918386 | C | T |
| rs8078340 | 26448013 | 3552 | IL1A | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.001085767 | 2016 | NOS2 | 17 | 27802186 | G | A |
| rs8078340 | 26448013 | 7124 | TNF | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.157314477 | 2016 | NOS2 | 17 | 27802186 | G | A |
| rs8078340 | 26448013 | 959 | CD40LG | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.004810009 | 2016 | NOS2 | 17 | 27802186 | G | A |
| rs8078340 | 26448013 | 3565 | IL4 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.009977336 | 2016 | NOS2 | 17 | 27802186 | G | A |
| rs8078340 | 26448013 | 4843 | NOS2 | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.139445464 | 2016 | NOS2 | 17 | 27802186 | G | A |
| rs8078340 | 26448013 | 55692 | LUC7L | umls:C0024530 | BeFree | A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324). | 0.000271442 | 2016 | NOS2 | 17 | 27802186 | G | A |
| rs8176719 | 22895189 | 28 | ABO | umls:C0024530 | GWASCAT | Genome-wide association study indicates two novel resistance loci for severe malaria. | 0.130358398 | 2012 | NA | 9 | 133257521 | - | C |
| rs8176722 | 23717212 | 28 | ABO | umls:C0024530 | GWASCAT | Imputation-based meta-analysis of severe malaria in three African populations. | 0.130358398 | 2013 | ABO | 9 | 133257367 | C | A |
| rs8177374 | 19602285 | 114609 | TIRAP | umls:C0024530 | BeFree | Low frequency of the TIRAP S180L polymorphism in Africa, and its potential role in malaria, sepsis, and leprosy. | 0.120814326 | 2009 | TIRAP | 11 | 126292948 | C | T |
| rs9429942 | 18954261 | 1378 | CR1 | umls:C0024530 | BeFree | The T allele of the reference single-nucleotide polymorphism rs9429942 in the CR1 promoter region was strongly associated with protection against cerebral malaria (2.2% of patients with mild malaria vs. 7.8% of patients with cerebral malaria; P = .0009; Bonferroni-adjusted Pc = .0306. | 0.124267125 | 2008 | CR1 | 1 | 207495285 | C | T |
| rs9658676 | 21625619 | 2194 | FASN | umls:C0024530 | BeFree | We found the A allele of c.-436C>A (rs9658676) located in the promoter region of FAS to be significantly associated with protection from severe childhood malaria (odds ratio 0.71, 95% confidence interval 0.58-0.88, p(empirical) = 0.02) and confirmed this finding in a replication group of 1,412 additional severe malaria cases and 2,659 community controls from the same geographic area. | 0.000542884 | 2011 | ACTA2;FAS | 10 | 88990441 | C | A |
| rs9940464 | 23717212 | 1012 | CDH13 | umls:C0024530 | GWASCAT | Imputation-based meta-analysis of severe malaria in three African populations. | 0.12 | 2013 | CDH13 | 16 | 83327170 | T | C |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:179) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 1 | 6829582 | rs448886 | C | A | rs448886 | 19465909 | 2.50E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 26475521 | rs868551 | A | G | rs868551 | 19465909 | 6.90E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 30923203 | rs454774 | G | T | rs454774 | 19465909 | 2.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 42026023 | rs10789394 | G | A | rs10789394 | 19465909 | 8.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 46321843 | rs6429582 | T | C | rs6429582 | 19465909 | 6.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 46346234 | rs10890361 | T | A | rs10890361 | 19465909 | 9.40E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 46356148 | rs10890363 | A | G | rs10890363 | 19465909 | 9.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 46363880 | rs7556436 | A | G | rs7556436 | 19465909 | 5.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 69520596 | rs1507860 | G | A | rs1507860 | 19465909 | 4.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 73245168 | rs10889990 | G | A | rs10889990 | 19465909 | 5.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 73245256 | rs10889991 | G | A | rs10889991 | 19465909 | 7.70E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 76435420 | rs12405994 | A | T | rs12405994 | 19465909 | 3.80E-07 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 76437196 | rs1417402 | G | A | rs1417402 | 19465909 | 5.00E-07 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 80538189 | rs1414411 | T | C | rs1414411 | 19465909 | 5.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 95554294 | rs7512953 | T | G | rs7512953 | 19465909 | 2.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 152780139 | rs7411365 | C | T | rs7411365 | 19465909 | 1.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 168560132 | rs7556321 | G | A | rs7556321 | 19465909 | 3.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 169712597 | rs10489181 | T | C | rs10489181 | 19465909 | 7.70E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 192763948 | rs10801153 | G | A | rs10801153 | 19465909 | 2.10E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 203654024 | rs10900585 | G | T | rs10900585 | 22895189 | 2.00E-10 | NA | 1.64 | NA | 1,325 African ancestry; 828 African ancestry controls | African(2153) | ALL(2153) | AFR(2153) | ALL(2153) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 203660781 | rs4951074 | A | G | rs4951074 | 22895189 | 1.80E-08 | NA | NA | NA | 1,325 African ancestry; 828 African ancestry controls | African(2153) | ALL(2153) | AFR(2153) | ALL(2153) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 204283624 | rs4245727 | C | G | rs4245727 | 19465909 | 1.40E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 1 | 237605491 | rs12087410 | C | G | rs12087410 | 19465909 | 7.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 66792109 | rs12614369 | A | G | rs12614369 | 19465909 | 3.60E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 77494953 | rs7563141 | G | T | rs7563141 | 19465909 | 7.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 107243678 | rs13025573 | G | A | rs13025573 | 19465909 | 2.90E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 138732281 | rs3113205 | C | G | rs3113205 | 19465909 | 3.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 185766912 | rs7590852 | T | C | rs7590852 | 23717212 | 4.16E-06 | NA | 1.17 | [1.09-1.25] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 185778262 | rs725617 | G | A | rs725617 | 23717212 | 4.60E-06 | NA | 1.17 | [1.09-1.25] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 185797228 | rs6755404 | A | C | rs6755404 | 23717212 | 1.00E-06 | NA | 1.26 | [1.15-1.38] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 231877319 | rs2136477 | G | A | rs2136477 | 19465909 | 5.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 231878496 | rs1543061 | C | T | rs1543061 | 19465909 | 9.60E-07 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 231878740 | rs10192428 | G | A | rs10192428 | 19465909 | 5.10E-07 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 231880112 | rs6750230 | G | A | rs6750230 | 19465909 | 1.60E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 231880308 | rs6750277 | C | T | rs6750277 | 19465909 | 6.60E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 2 | 233067832 | rs4973508 | T | A | rs4973508 | 19465909 | 1.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 3 | 36516326 | rs1350146 | G | A | rs1350146 | 19465909 | 4.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 3 | 43132444 | rs488069 | C | T | rs488069 | 19465909 | 7.60E-07 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 3 | 73869793 | rs9848344 | G | A | rs9848344 | 19465909 | 8.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 3 | 119504140 | rs11712211 | T | C | rs11712211 | 19465909 | 6.80E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 3 | 135282024 | rs9833932 | C | T | rs9833932 | 19465909 | 4.70E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 3 | 184875106 | rs6797705 | G | C | rs6797705 | 19465909 | 3.20E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 4 | 5527249 | rs2267654 | A | G | rs2267654 | 19465909 | 8.50E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 4 | 26503983 | rs2046784 | G | A | rs2046784 | 19465909 | 2.50E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 4 | 26504157 | rs2130250 | G | T | rs2130250 | 19465909 | 3.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 4 | 107305565 | rs2949632 | G | A | rs2949632 | 19465909 | 6.50E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 4 | 107310444 | rs2949641 | A | G | rs2949641 | 19465909 | 1.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 4 | 160684694 | rs4690956 | A | G | rs4690956 | 19465909 | 3.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 5 | 1300025 | rs2853668 | G | T | rs2853668 | 19465909 | 2.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 5 | 43004280 | rs316414 | A | G | rs316414 | 19465909 | 4.50E-07 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 5 | 43016650 | rs222060 | C | T | rs222060 | 19465909 | 7.40E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 5 | 43094029 | rs316413 | T | C | rs316413 | 19465909 | 7.90E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 5 | 79100717 | rs259065 | A | G | rs259065 | 19465909 | 9.40E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 5 | 90725887 | rs4432929 | C | T | rs4432929 | 19465909 | 1.30E-04 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 5 | 104335746 | rs2403256 | A | T | rs2403256 | 19465909 | 5.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 5 | 113227270 | rs4449520 | G | C | rs4449520 | 19465909 | 4.90E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 5 | 131370712 | rs10074987 | G | A | rs10074987 | 19465909 | 7.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 5 | 142289541 | rs830532 | C | T | rs830532 | 20657648 | 3.70E-05 | P. falciparum infection intensity and mild malaria attack (Intensity of plasmodial infection) | NA | NA | 626 African ancestry samples | African(626) | ALL(626) | AFR(626) | ALL(626) | Malarial infection | HPOID:0002718 | Recurrent bacterial infections | DOID:12365 | malaria | NA | NA | NA | NA | Malaria | NA | Research Support, Non-U.S. Gov't | A | ARHGAP26 |
| 5 | 149014418 | rs1056189 | A | G | rs1056189 | 20657648 | 8.50E-04 | P. falciparum infection intensity and mild malaria attack (Mean level of P. falciparum density) | NA | NA | 626 African ancestry samples | African(626) | ALL(626) | AFR(626) | ALL(626) | Malarial infection | HPOID:0002718 | Recurrent bacterial infections | DOID:12365 | malaria | NA | NA | NA | NA | Malaria | NA | Research Support, Non-U.S. Gov't | A | ARHGEF37 |
| 6 | 64058565 | rs1741797 | T | C | rs1741797 | 19465909 | 5.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 6 | 68475531 | rs4541731 | T | C | rs4541731 | 19465909 | 5.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 6 | 81332877 | rs2444796 | A | G | rs2444796 | 19465909 | 7.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 6 | 87739154 | rs17822183 | C | T | rs17822183 | 19465909 | 3.90E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 6 | 106207093 | rs6568402 | A | G | rs6568402 | 19465909 | 8.60E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 6 | 141096809 | rs647706 | A | T | rs647706 | 19465909 | 6.90E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 6 | 151228071 | rs712209 | T | C | rs712209 | 19465909 | 1.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 6 | 162344712 | rs9458419 | C | T | rs9458419 | 19465909 | 1.40E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 7 | 45250348 | rs1294878 | T | C | rs1294878 | 19465909 | 8.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 7 | 50622712 | rs1451375 | C | A | rs1451375 | 19465909 | 6.00E-06 | NA | 1.33 | [1.18-1.52] | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 7 | 50623451 | rs10249420 | C | G | rs10249420 | 19465909 | 6.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 7 | 50625898 | rs7803788 | C | T | rs7803788 | 19465909 | 7.90E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 7 | 132064886 | rs10269601 | C | A | rs10269601 | 19465909 | 1.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 7 | 132069727 | rs4731867 | T | G | rs4731867 | 19465909 | 9.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 7 | 153399165 | rs1558301 | A | G | rs1558301 | 19465909 | 5.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 8 | 13557493 | rs2410094 | C | T | rs2410094 | 19465909 | 6.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 8 | 13560003 | rs1384057 | G | A | rs1384057 | 19465909 | 2.40E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 8 | 58789168 | rs10504248 | T | C | rs10504248 | 19465909 | 7.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 8 | 91440226 | rs2205156 | T | C | rs2205156 | 19465909 | 5.70E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 8 | 103574663 | rs2436893 | G | A | rs2436893 | 19465909 | 5.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 8 | 120941528 | rs4871793 | C | T | rs4871793 | 19465909 | 1.10E-04 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 8 | 128204216 | rs1473581 | C | T | rs1473581 | 19465909 | 4.50E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 107457275 | rs10820709 | A | C | rs10820709 | 19465909 | 5.90E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 132008768 | rs7023548 | C | T | rs7023548 | 23717212 | 1.34E-07 | NA | 1.28 | [1.17-1.40] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136121303 | rs7855466 | C | T | rs7855466 | 23717212 | 5.51E-07 | NA | 1.16 | [1.10-1.24] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136131022 | rs8176751 | C | T | rs8176751 | 23717212 | 1.06E-09 | NA | 1.26 | [1.17-1.36] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136131188 | rs8176749 | C | T | rs8176749 | 23717212 | 1.20E-07 | NA | 1.23 | [1.14-1.33] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136131322 | rs8176746 | G | T | rs8176746 | 23717212 | 1.14E-07 | NA | 1.23 | [1.14-1.33] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136131415 | rs8176743 | C | T | rs8176743 | 23717212 | 8.29E-08 | NA | 1.23 | [1.14-1.33] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136132754 | rs8176722 | C | A | rs8176722 | 23717212 | 9.00E-10 | NA | 1.28 | [1.19-1.39] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136132908 | rs77641731 | T | C | rs8176719 | 22895189 | 4.00E-21 | NA | 1.48 | NA | 1,325 African ancestry; 828 African ancestry controls | African(2153) | ALL(2153) | AFR(2153) | ALL(2153) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136132908 | rs8176719 | T | TC | rs8176719 | 22895189 | 4.00E-21 | NA | 1.48 | NA | 1,325 African ancestry; 828 African ancestry controls | African(2153) | ALL(2153) | AFR(2153) | ALL(2153) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136135863 | rs8176703 | G | T | rs8176703 | 22895189 | 2.10E-12 | NA | NA | NA | 1,325 African ancestry; 828 African ancestry controls | African(2153) | ALL(2153) | AFR(2153) | ALL(2153) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136137657 | rs8176693 | C | T | rs8176693 | 23717212 | 3.73E-08 | NA | 1.26 | [1.16-1.36] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136142185 | rs8176672 | C | T | rs8176672 | 23717212 | 4.85E-08 | NA | 1.26 | [1.16-1.37] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 9 | 136149229 | rs505922 | T | C | rs505922 | 23717212 | 2.32E-08 | NA | 1.18 | [1.11-1.25] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 10 | 4564553 | rs1904667 | A | G | rs1904667 | 19465909 | 1.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 10 | 5652237 | rs7924096 | G | C | rs7924096 | 19465909 | 4.40E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 10 | 23094828 | rs946961 | G | C | rs946961 | 19465909 | 6.90E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 10 | 23098092 | rs11013140 | T | C | rs11013140 | 19465909 | 5.60E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 10 | 69547057 | rs4746711 | A | G | rs4746711 | 19465909 | 9.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 10 | 101104712 | rs10786538 | G | A | rs10786538 | 19465909 | 2.50E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 10 | 101105002 | rs11190062 | A | G | rs11190062 | 19465909 | 1.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 10 | 126338444 | rs7076268 | C | T | rs7076268 | 19465909 | 1.60E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 10 | 126399566 | rs4962686 | T | C | rs4962686 | 19465909 | 7.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 10 | 128213658 | rs1370108 | C | T | rs1370108 | 19465909 | 1.50E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4592277 | rs1505209 | A | G | rs1505209 | 23717212 | 2.01E-08 | NA | 1.62 | [1.37-1.91] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4715946 | rs7105156 | A | G | rs7105156 | 19465909 | 7.10E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4790575 | rs12788102 | A | G | rs12788102 | 23717212 | 2.00E-16 | NA | 2.15 | [1.79-2.59] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4794119 | rs12789492 | C | T | rs12789492 | 23717212 | 3.89E-16 | NA | 2.11 | [1.76-2.52] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4799209 | rs1594812 | T | G | rs1594812 | 23717212 | 1.32E-15 | NA | 2.09 | [1.74-2.50] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4806872 | rs12806476 | T | G | rs12806476 | 23717212 | 4.40E-16 | NA | 2.1 | [1.76-2.51] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4807054 | rs12801757 | A | G | rs12801757 | 23717212 | 2.11E-15 | NA | 2.06 | [1.73-2.47] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4807972 | rs12808215 | A | G | rs12808215 | 23717212 | 9.20E-15 | NA | 2.01 | [1.69-2.40] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4808133 | rs17325567 | T | C | rs17325567 | 23717212 | 4.06E-16 | NA | 2.1 | [1.75-2.50] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4808425 | rs17227978 | G | A | rs17227978 | 23717212 | 4.26E-16 | NA | 2.09 | [1.75-2.50] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4810364 | rs17228092 | T | C | rs17228092 | 23717212 | 4.51E-16 | NA | 2.1 | [1.76-2.51] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4811800 | rs17228176 | A | G | rs17228176 | 23717212 | 7.03E-16 | NA | 2.09 | [1.75-2.50] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 4811883 | rs17228183 | G | A | rs17228183 | 23717212 | 7.05E-16 | NA | 2.09 | [1.75-2.50] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5019985 | rs16908208 | T | C | rs16908208 | 19465909 | 1.40E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5060941 | rs2034839 | G | A | rs2034839 | 19465909 | 4.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5061541 | rs2499984 | A | G | rs2499984 | 19465909 | 7.70E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5067358 | rs2500012 | C | T | rs2500012 | 19465909 | 4.40E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5067389 | rs2500013 | G | T | rs2500013 | 19465909 | 8.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5072835 | rs2959184 | C | T | rs2959184 | 19465909 | 2.90E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5096331 | rs4144715 | A | G | rs4144715 | 23717212 | 6.07E-06 | NA | 1.14 | [1.08-1.21] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5225635 | rs11036238 | G | C | rs11036238 | 19465909 | 4.00E-11 | NA | 1.59 | [1.39-1.82] | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5248232 | rs281864519 | TCA | T | rs334 | 19465909 | 1.30E-28 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5248232 | rs281864519 | TCA | T | rs334 | 22895189 | 1.40E-38 | NA | NA | NA | 1,325 African ancestry; 828 African ancestry controls | African(2153) | ALL(2153) | AFR(2153) | ALL(2153) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5248232 | rs334 | T | A,C,G | rs334 | 19465909 | 1.30E-28 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5248232 | rs334 | T | A,C,G | rs334 | 22895189 | 1.40E-38 | NA | NA | NA | 1,325 African ancestry; 828 African ancestry controls | African(2153) | ALL(2153) | AFR(2153) | ALL(2153) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5308896 | rs11036635 | G | A | rs11036635 | 19465909 | 4.80E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5372690 | rs4373970 | A | G | rs4373970 | 19465909 | 6.70E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5406123 | rs4910780 | T | C | rs4910780 | 19465909 | 2.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5442226 | rs17359438 | T | C | rs17359438 | 19465909 | 1.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5463425 | rs16931041 | T | C | rs16931041 | 19465909 | 1.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5518156 | rs372091 | A | G | rs372091 | 22895189 | 6.00E-14 | NA | 2.17 | NA | 1,325 African ancestry; 828 African ancestry controls | African(2153) | ALL(2153) | AFR(2153) | ALL(2153) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 5545822 | rs2010794 | A | T | rs2010794 | 19465909 | 4.80E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 11766709 | rs11022014 | T | C | rs11022014 | 19465909 | 4.90E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 19297062 | rs11025082 | G | A | rs11025082 | 19465909 | 5.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 93691008 | rs1518555 | A | C | rs1518555 | 19465909 | 2.70E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 95953493 | rs16923343 | G | A | rs16923343 | 19465909 | 2.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 110739555 | rs11213630 | A | G | rs11213630 | 23717212 | 3.03E-07 | NA | 1.19 | [1.12-1.28] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 110741014 | rs1469170 | A | G | rs1469170 | 23717212 | 8.00E-08 | NA | 1.2 | [1.12-1.29] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 11 | 132911101 | rs11223336 | A | G | rs11223336 | 19465909 | 8.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 12 | 104902190 | rs2141857 | C | A | rs2141857 | 19465909 | 6.60E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 13 | 23346768 | rs4770301 | T | C | rs4770301 | 19465909 | 3.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 13 | 36615408 | rs1750719 | G | T | rs1750719 | 19465909 | 9.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 13 | 39779861 | rs7330452 | A | C | rs7330452 | 19465909 | 8.60E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 13 | 54296049 | rs2806735 | A | G | rs2806735 | 19465909 | 9.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 13 | 93699203 | rs1444227 | G | C | rs1444227 | 19465909 | 3.60E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 13 | 93712869 | rs1158878 | G | A | rs1158878 | 19465909 | 4.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 14 | 36854136 | rs12590640 | C | T | rs12590640 | 23717212 | 4.00E-06 | NA | 1.15 | [1.09-1.23] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 14 | 46366562 | rs17726637 | C | T | rs17726637 | 19465909 | 1.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 14 | 46434585 | rs6572335 | A | G | rs6572335 | 19465909 | 9.30E-07 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 14 | 46467831 | rs17728971 | A | G | rs17728971 | 19465909 | 6.50E-07 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 14 | 81853407 | rs1569012 | C | T | rs1569012 | 19465909 | 2.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 15 | 27773791 | rs3097490 | G | A | rs3097490 | 19465909 | 6.70E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 15 | 31234064 | rs6493352 | C | T | rs6493352 | 19465909 | 3.60E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 15 | 53545261 | rs492391 | G | A | rs492391 | 19465909 | 2.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 16 | 57468408 | rs16957051 | T | C | rs16957051 | 19465909 | 2.50E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 16 | 57503330 | rs2161647 | C | A | rs2161647 | 19465909 | 4.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 16 | 71653637 | rs2334880 | A | G | rs2334880 | 22895189 | 2.00E-06 | NA | 1.19 | NA | 1,325 African ancestry; 828 African ancestry controls | African(2153) | ALL(2153) | AFR(2153) | ALL(2153) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 16 | 78926616 | rs11647676 | T | A | rs11647676 | 19465909 | 9.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 16 | 78930216 | rs2292124 | G | C | rs2292124 | 19465909 | 3.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 16 | 83348824 | rs1035569 | A | G | rs1035569 | 23717212 | 2.20E-06 | NA | 1.17 | [1.09-1.24] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 16 | 83349398 | rs7194029 | T | C | rs7194029 | 23717212 | 3.67E-06 | NA | 1.16 | [1.09-1.24] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 16 | 83360775 | rs9940464 | T | C | rs9940464 | 23717212 | 5.00E-07 | NA | 1.17 | [1.10-1.25] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 16 | 83368400 | rs10514577 | G | C | rs10514577 | 23717212 | 1.06E-06 | NA | 1.17 | [1.10-1.24] | 5,425 African cases; 6,891 African controls | African(12316) | ALL(12316) | AFR(12316) | ALL(12316) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 17 | 10574159 | rs6503319 | C | T | rs6503319 | 19465909 | 7.00E-07 | NA | 1.21 | [1.12-1.31] | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 18 | 24250211 | rs12960395 | G | A | rs12960395 | 19465909 | 5.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 19 | 6941161 | rs460375 | G | C | rs460375 | 19465909 | 1.20E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 19 | 6941867 | rs465543 | G | A | rs465543 | 19465909 | 6.10E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 19 | 41804976 | rs11879562 | G | C | rs11879562 | 19465909 | 5.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 19 | 58648359 | rs159667 | C | T | rs159667 | 19465909 | 7.80E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 20 | 19348676 | rs6112327 | A | T | rs6112327 | 19465909 | 1.00E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 20 | 51923969 | rs6512879 | T | G | rs6512879 | 19465909 | 4.30E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 21 | 16790213 | rs2823263 | T | C | rs2823263 | 19465909 | 1.80E-06 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 22 | 35242350 | rs7286095 | G | A | rs7286095 | 19465909 | 4.60E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
| 22 | 38753956 | rs6001102 | C | G | rs6001102 | 19465909 | 8.40E-05 | NA | NA | NA | 958 African ancestry cases; 1,382 African ancestry controls; all children | African(2340) | ALL(2340) | AFR(2340) | ALL(2340) | Malaria | HPOID:0004386 | HPOID:0002315 | HPOID:0001945 | HPOID:0002829 | HPOID:0002013 | HPOID:0002018 | HPOID:0001878 | HPOID:0000952 | HPOID:0003641 | HPOID:0000480 | HPOID:0001279 | Gastrointestinal inflammation | Headache |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
Chemical(Total Drugs:14) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0024530 | amodiaquine | D000655 | 86-42-0 | malaria | MESH:D008288 | therapeutic | 14717048 | ||
| C0024530 | atovaquone | D053626 | 94015-53-9 | malaria | MESH:D008288 | therapeutic | 10447880 | ||
| C0024530 | chloroquine | D002738 | 1954/5/7 | malaria | MESH:D008288 | therapeutic | 1029911 | ||
| C0024530 | chlorpromazine | D002746 | 50-53-3 | malaria | MESH:D008288 | therapeutic | 23129054 | ||
| C0024530 | ciprofloxacin | D002939 | 85721-33-1 | malaria | MESH:D008288 | therapeutic | 7596948 | ||
| C0024530 | cyproheptadine | D003533 | 129-03-3 | malaria | MESH:D008288 | therapeutic | 23129054 | ||
| C0024530 | dapsone | D003622 | 80-08-0 | malaria | MESH:D008288 | therapeutic | 18602405 | ||
| C0024530 | doxycycline | D004318 | 564-25-0 | malaria | MESH:D008288 | therapeutic | 12649241 | ||
| C0024530 | halofantrine | C023768 | 36167-63-2 | malaria | MESH:D008288 | therapeutic | 15934850 | ||
| C0024530 | imipramine | D007099 | 50-49-7 | malaria | MESH:D008288 | therapeutic | 23129054 | ||
| C0024530 | mefloquine | D015767 | 53230-10-7 | malaria | MESH:D008288 | therapeutic | 10457122 | ||
| C0024530 | protriptyline | D011530 | 438-60-8 | malaria | MESH:D008288 | therapeutic | 23129054 | ||
| C0024530 | pyrimethamine | D011739 | 58-14-0 | malaria | MESH:D008288 | therapeutic | 1124444 | ||
| C0024530 | quinine | D011803 | 130-95-0 | malaria | MESH:D008288 | therapeutic | 15107507 | ||
FDA approved drug and dosage information(Total Drugs:2) | ||||||||
|---|---|---|---|---|---|---|---|---|
| DiseaseID | Drug_name | active_ingredients | strength | Dosage Form/Route | Marketing Status | TE code | RLD | RS |
| MESH:D008288 | cipro | ciprofloxacin | 400MG/40ML (10MG/ML) | INJECTABLE;INJECTION | Discontinued | None | Yes | No |
| MESH:D008288 | cipro | ciprofloxacin | 250MG/5ML | FOR SUSPENSION;ORAL | Prescription | AB | Yes | No |
FDA labeling changes(Total Drugs:2) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DiseaseID | Pediatric_Labeling_Date | Trade_Name | Generic_Name_or_Proper_Name | Indications Studied | Label Changes Summary | Product Labeling | BPCA(B) | PREA(P) | BPCA(B) and PREA(P) | Pediatric Rule (R) | Sponsor | Pediatric Exclusivity Granted Date | NNPS |
| MESH:D008288 | 03/25/2004 | cipro | ciprofloxacin | Complicated UTI and pyelonephritis | Indicated for the treatment of complicated urinary tract infections (cUTIs) and pyelonephritis in pediatric patients 1 17 years of age Not drug of first choice due to increased adverse events compared to controls including events related to joints and/or surrounding tissues Information on PK and dose in pediatric patients 1 17 years of age The most frequent adverse events observed within 6 weeks of treatment initiation during the cUTI clinical trial were gastrointestinal 15% compared to 9% and musculoskeletal 9.3% compared to 6% in ciprofloxacin-treated compared to control-treated patients, respectively | Labeling | B | - | - | - | Bayer | 12/18/2003 | FALSE' |
| MESH:D008288 | 03/25/2004 | cipro | ciprofloxacin | Complicated UTI and pyelonephritis | Indicated for the treatment of complicated urinary tract infections (cUTIs) and pyelonephritis in pediatric patients 1 17 years of age Not drug of first choice due to increased adverse events compared to controls including events related to joints and/or surrounding tissues Information on PK and dose in pediatric patients 1 17 years of age The most frequent adverse events observed within 6 weeks of treatment initiation during the cUTI clinical trial were gastrointestinal 15% compared to 9% and musculoskeletal 9.3% compared to 6% in ciprofloxacin-treated compared to control-treated patients, respectively | Labeling | B | - | - | - | Bayer | 12/18/2003 | FALSE' |