PedAM
Pediatric Disease Annotations & Medicines
| macrophagic myofasciitis | ||||
| Disease ID | 1673 |
|---|---|
| Disease | macrophagic myofasciitis |
| Definition | A rare systemic inflammatory disease associated with long-lasting biopersistance of post-vaccinal aluminic granulomas. More than 600 cases have been reported to date, most of them in France. This is probably due to large-scale vaccination with aluminum-containing vaccines in France during the 1990s. The disease generally manifests with myalgias of variable intensity, and is usually associated with weakness and chronic fatigue. Belongs to the group of Autoimmune/inflammatory Syndromes Induced by Adjuvants (ASIA): it is triggered, probably in genetically predisposed patients, by injection of vaccines containing aluminum hydroxide and may occur up to 10 years following vaccination. |
| Synonym | macrophagic myofasciitis (disorder) mmf - macrophagic myofasciitis |
| Orphanet | |
| UMLS | C2931639 |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:2) |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1673 |
|---|---|
| Disease | macrophagic myofasciitis |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:6) HP:0001945 | Fever HP:0002829 | Arthralgia HP:0003457 | EMG abnormality HP:0003324 | Generalized muscle weakness HP:0012378 | Fatigue HP:0003326 | Myalgia |
| Text Mined Phenotype | (Waiting for update.) |
| Disease ID | 1673 |
|---|---|
| Disease | macrophagic myofasciitis |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0004370 | Abnormality of temperature regulation | MP:0001777 | abnormal body temperature homeostasis;HP:0001324 | Muscle weakness |
Mapped by homologous gene(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0004370 | Abnormality of temperature regulation | MP:0002498 | abnormal acute inflammation;HP:0001324 | Muscle weakness |
Chemical(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |