PedAM
Pediatric Disease Annotations & Medicines
| lymphocele | ||||
| Disease ID | 1355 |
|---|---|
| Disease | lymphocele |
| Definition | Cystic mass containing lymph from diseased lymphatic channels or following surgical trauma or other injury. |
| Synonym | cyst lymph cyst, lymphatic cysts lymph cysts, lymphatic lymph cyst lymph cyst (disorder) lymphatic cyst lymphatic cysts lymphocele (disorder) lymphocele [disease/finding] lymphoceles lymphocoele lymphocoeles lymphocyst lymphocyst (morphologic abnormality) lymphocysts |
| DOID | |
| UMLS | C0024248 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:9) C0040053 | thrombosis | 2 C0476089 | endometrial cancer | 1 C0476089 | endometrial cancers | 1 C0034065 | pulmonary embolism | 1 C0041296 | tuberculosis | 1 C0011847 | diabetes | 1 C0024236 | lymphedema | 1 C0476089 | endometrial ca | 1 C0376358 | prostate cancer | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:27) 9479 | MAPK8IP1 | DISEASES 10343 | PKDREJ | DISEASES 6558 | SLC12A2 | DISEASES 23523 | CABIN1 | DISEASES 4036 | LRP2 | DISEASES 8626 | TP63 | DISEASES 5921 | RASA1 | DISEASES 6750 | SST | DISEASES 5798 | PTPRN | DISEASES 213 | ALB | DISEASES 29123 | ANKRD11 | DISEASES 354 | KLK3 | DISEASES 342898 | SYCN | DISEASES 9159 | PCSK7 | DISEASES 399694 | SHC4 | DISEASES 23542 | MAPK8IP2 | DISEASES 2621 | GAS6 | DISEASES 5587 | PRKD1 | DISEASES 1811 | SLC26A3 | DISEASES 2475 | MTOR | DISEASES 5225 | PGC | DISEASES 3105 | HLA-A | DISEASES 3239 | HOXD13 | DISEASES 6164 | RPL34 | DISEASES 8091 | HMGA2 | DISEASES 6336 | SCN10A | DISEASES 3925 | STMN1 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1355 |
|---|---|
| Disease | lymphocele |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:7) |
| Disease ID | 1355 |
|---|---|
| Disease | lymphocele |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
Chemical(Total Drugs:1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0024248 | sirolimus | D020123 | 53123-88-9 | lymphocele | MESH:D008210 | marker/mechanism | 12364859 | ||
FDA approved drug and dosage information(Total Drugs:2) | ||||||||
|---|---|---|---|---|---|---|---|---|
| DiseaseID | Drug_name | active_ingredients | strength | Dosage Form/Route | Marketing Status | TE code | RLD | RS |
| MESH:D008210 | rapamune | sirolimus | 1MG/ML | SOLUTION;ORAL | Prescription | None | Yes | Yes |
| MESH:D008210 | rapamune | sirolimus | 1MG | TABLET;ORAL | Prescription | AB | Yes | No |
FDA labeling changes(Total Drugs:2) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DiseaseID | Pediatric_Labeling_Date | Trade_Name | Generic_Name_or_Proper_Name | Indications Studied | Label Changes Summary | Product Labeling | BPCA(B) | PREA(P) | BPCA(B) and PREA(P) | Pediatric Rule (R) | Sponsor | Pediatric Exclusivity Granted Date | NNPS |
| MESH:D008210 | 11/3/2005 | rapamune | sirolimus | Prophylaxis of organ rejection in patients undergoing renal transplants | Safety and efficacy established in children 13 years or older judged to be at low to moderate immunologic risk Safety was assessed in a controlled clinical trial in pediatric ( | Labeling | B | - | - | - | Wyeth | 11/17/2004 | FALSE' |
| MESH:D008210 | 11/3/2005 | rapamune | sirolimus | Prophylaxis of organ rejection in patients undergoing renal transplants | Safety and efficacy established in children 13 years or older judged to be at low to moderate immunologic risk Safety was assessed in a controlled clinical trial in pediatric ( | Labeling | B | - | - | - | Wyeth | 11/17/2004 | FALSE' |