PedAM

Pediatric Disease Annotations & Medicines


	lymphoblastic lymphoma

Disease ID	1202
Disease	lymphoblastic lymphoma
Definition	A lymphoma composed of immature small to medium-sized precursor lymphoid cells (lymphoblasts). It includes the B- and T-cell lymphoblastic lymphoma.
Synonym	[m]lymphoblastic lymphoma nos diffuse lymphoblastic lymphoma diffuse lymphoblastic lymphosarcoma diffuse lymphoblastic malignant lymphoma diffuse lymphoblastoma diffuse non-hodgkin lymphoma, lymphoblastic diffuse non-hodgkin's lymphoma, lymphoblastic diffuse non-hodgkin's lymphoma, lymphoblastic (clinical) diffuse non-hodgkin's lymphoma, lymphoblastic (disorder) lymphoblastic lymphoma, diffuse lymphoblastic lymphosarcoma lymphoblastic malignant lymphoma lymphoblastoma lymphoblastoma [obs] lymphoma lymphoblastic lymphoma, lymphoblastic, malignant malignant lymphoma - lymphoblastic malignant lymphoma, convoluted cell malignant lymphoma, convoluted cell [obs] malignant lymphoma, lymphoblastic malignant lymphoma, lymphoblastic (morphologic abnormality) malignant lymphoma, lymphoblastic -retired- precursor cell lymphoblastic lymphoma precursor cell lymphoblastic lymphoma (morphologic abnormality) precursor lymphoblastic lymphoma
DOID	DOID:0080147
UMLS	C0079748
SNOMED-CT	SNOMEDCT_US_2016_09_01:109965004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:18) C0024299 \| lymphoma \| 4 C0023470 \| myeloid leukemia \| 3 C0019618 \| histiocytosis \| 2 C0023467 \| acute myeloid leukemia \| 2 C0023418 \| leukemia \| 2 C0042769 \| virus infection \| 2 C0019621 \| langerhans cell histiocytosis \| 2 C0023473 \| chronic myeloid leukemia \| 1 C0023448 \| lymphoblastic leukemia \| 1 C0023449 \| acute lymphoblastic leukemia \| 1 C0151332 \| active tuberculosis \| 1 C0028754 \| obesity \| 1 C0041296 \| tuberculosis \| 1 C1258215 \| ileus \| 1 C0001125 \| lactic acidosis \| 1 C0079731 \| b-cell lymphoma \| 1 C0494165 \| hepatic metastasis \| 1 C1333375 \| ectopic thymus \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:170) 972 \| CD74 \| DISEASES 9603 \| NFE2L3 \| DISEASES 933 \| CD22 \| DISEASES 6561 \| SLC13A1 \| DISEASES 990 \| CDC6 \| DISEASES 1113 \| CHGA \| DISEASES 973 \| CD79A \| DISEASES 51384 \| WNT16 \| DISEASES 944 \| TNFSF8 \| DISEASES 4353 \| MPO \| DISEASES 1440 \| CSF3 \| DISEASES 8456 \| FOXN1 \| DISEASES 952 \| CD38 \| DISEASES 3558 \| IL2 \| DISEASES 116449 \| CLNK \| DISEASES 595 \| CCND1 \| DISEASES 1027 \| CDKN1B \| DISEASES 2026 \| ENO2 \| DISEASES 26127 \| FGFR1OP2 \| DISEASES 10279 \| PRSS16 \| DISEASES 6534 \| SLC6A7 \| DISEASES 604 \| BCL6 \| DISEASES 22924 \| MAPRE3 \| DISEASES 5624 \| PROC \| DISEASES 27434 \| POLM \| DISEASES 6299 \| SALL1 \| DISEASES 3998 \| LMAN1 \| DISEASES 57418 \| WDR18 \| DISEASES 10752 \| CHL1 \| DISEASES 8739 \| HRK \| DISEASES 1840 \| DTX1 \| DISEASES 9883 \| POM121 \| DISEASES 4005 \| LMO2 \| DISEASES 10017 \| BCL2L10 \| DISEASES 10113 \| PREB \| DISEASES 4069 \| LYZ \| DISEASES 8140 \| SLC7A5 \| DISEASES 1975 \| EIF4B \| DISEASES 945 \| CD33 \| DISEASES 4025 \| LPO \| DISEASES 84662 \| GLIS2 \| DISEASES 9618 \| TRAF4 \| DISEASES 6929 \| TCF3 \| DISEASES 5264 \| PHYH \| DISEASES 6855 \| SYP \| DISEASES 943 \| TNFRSF8 \| DISEASES 10382 \| TUBB4A \| DISEASES 4066 \| LYL1 \| DISEASES 5924 \| RASGRF2 \| DISEASES 4683 \| NBN \| DISEASES 7994 \| KAT6A \| DISEASES 1021 \| CDK6 \| DISEASES 51411 \| BIN2 \| DISEASES 23067 \| SETD1B \| DISEASES 7157 \| TP53 \| DISEASES 6455 \| SH3GL1 \| DISEASES 63978 \| PRDM14 \| DISEASES 1030 \| CDKN2B \| DISEASES 4851 \| NOTCH1 \| DISEASES 55294 \| FBXW7 \| DISEASES 2838 \| GPR15 \| DISEASES 7345 \| UCHL1 \| DISEASES 3815 \| KIT \| DISEASES 89858 \| SIGLEC12 \| DISEASES 6777 \| STAT5B \| DISEASES 1973 \| EIF4A1 \| DISEASES 6886 \| TAL1 \| DISEASES 10206 \| TRIM13 \| DISEASES 10818 \| FRS2 \| DISEASES 201161 \| CENPV \| DISEASES 290 \| ANPEP \| DISEASES 915 \| CD3D \| DISEASES 81620 \| CDT1 \| DISEASES 8772 \| FADD \| DISEASES 613 \| BCR \| DISEASES 171558 \| PTCRA \| DISEASES 8625 \| RFXANK \| DISEASES 8028 \| MLLT10 \| DISEASES 27087 \| B3GAT1 \| DISEASES 64978 \| MRPL38 \| DISEASES 3265 \| HRAS \| DISEASES 947 \| CD34 \| DISEASES 10125 \| RASGRP1 \| DISEASES 924 \| CD7 \| DISEASES 7172 \| TPMT \| DISEASES 84883 \| AIFM2 \| DISEASES 92745 \| SLC38A5 \| DISEASES 931 \| MS4A1 \| DISEASES 147912 \| SIX5 \| DISEASES 4684 \| NCAM1 \| DISEASES 55024 \| BANK1 \| DISEASES 1351 \| COX8A \| DISEASES 6664 \| SOX11 \| DISEASES 923 \| CD6 \| DISEASES 11284 \| PNKP \| DISEASES 2027 \| ENO3 \| DISEASES 951 \| CD37 \| DISEASES 1974 \| EIF4A2 \| DISEASES 3563 \| IL3RA \| DISEASES 3543 \| IGLL1 \| DISEASES 81608 \| FIP1L1 \| DISEASES 3932 \| LCK \| DISEASES 3824 \| KLRD1 \| DISEASES 4004 \| LMO1 \| DISEASES 23583 \| SMUG1 \| DISEASES 3266 \| ERAS \| DISEASES 6776 \| STAT5A \| DISEASES 132884 \| EVC2 \| DISEASES 921 \| CD5 \| DISEASES 2335 \| FN1 \| DISEASES 219844 \| HYLS1 \| DISEASES 1822 \| ATN1 \| DISEASES 5079 \| PAX5 \| DISEASES 4149 \| MAX \| DISEASES 2526 \| FUT4 \| DISEASES 117583 \| PARD3B \| DISEASES 7037 \| TFRC \| DISEASES 6693 \| SPN \| DISEASES 4311 \| MME \| DISEASES 5475 \| PPEF1 \| DISEASES 5693 \| PSMB5 \| DISEASES 961 \| CD47 \| DISEASES 1378 \| CR1 \| DISEASES 1380 \| CR2 \| DISEASES 5788 \| PTPRC \| DISEASES 51022 \| GLRX2 \| DISEASES 1314 \| COPA \| DISEASES 154215 \| NKAIN2 \| DISEASES 4942 \| OAT \| DISEASES 914 \| CD2 \| DISEASES 965 \| CD58 \| DISEASES 3195 \| TLX1 \| DISEASES 959 \| CD40LG \| DISEASES 1647 \| GADD45A \| DISEASES 1791 \| DNTT \| DISEASES 25 \| ABL1 \| DISEASES 100 \| ADA \| DISEASES 896 \| CCND3 \| DISEASES 5090 \| PBX3 \| DISEASES 7027 \| TFDP1 \| DISEASES 4524 \| MTHFR \| DISEASES 4609 \| MYC \| DISEASES 64225 \| ATL2 \| DISEASES 3559 \| IL2RA \| DISEASES 54790 \| TET2 \| DISEASES 4267 \| CD99 \| DISEASES 80333 \| KCNIP4 \| DISEASES 7750 \| ZMYM2 \| DISEASES 238 \| ALK \| DISEASES 340152 \| ZC3H12D \| DISEASES 3239 \| HOXD13 \| DISEASES 838 \| CASP5 \| DISEASES 347734 \| SLC35B2 \| DISEASES 196410 \| METTL7B \| DISEASES 83478 \| ARHGAP24 \| DISEASES 55120 \| FANCL \| DISEASES 7441 \| VPREB1 \| DISEASES 29072 \| SETD2 \| DISEASES 2260 \| FGFR1 \| DISEASES 81542 \| TMX1 \| DISEASES 1438 \| CSF2RA \| DISEASES 1029 \| CDKN2A \| DISEASES 2313 \| FLI1 \| DISEASES 2130 \| EWSR1 \| DISEASES 7072 \| TIA1 \| DISEASES 6158 \| RPL28 \| DISEASES 26054 \| SENP6 \| DISEASES 4049 \| LTA \| DISEASES 22862 \| FNDC3A \| DISEASES 930 \| CD19 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1202
Disease	lymphoblastic lymphoma
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:16) HP:0002665 \| Lymphoma \| 4 HP:0012324 \| Myeloid leukemia \| 3 HP:0004808 \| Acute myelogenous leukemia \| 2 HP:0100727 \| Histiocytosis \| 2 HP:0001909 \| Leukemia \| 2 HP:0006721 \| Acute lymphocytic leukemia \| 1 HP:0002664 \| Neoplasia \| 1 HP:0012191 \| B-cell lymphoma \| 1 HP:0005506 \| Chronic myeloid leukemia \| 1 HP:0003128 \| Lactic acidosis \| 1 HP:0001513 \| Obesity \| 1 HP:0001941 \| acidemia \| 1 HP:0002595 \| Gastrointestinal atony \| 1 HP:0001880 \| Eosinophilia \| 1 HP:0002716 \| Lymph node hyperplasia \| 1 HP:0002202 \| Pleural effusion \| 1

Disease ID	1202
Disease	lymphoblastic lymphoma
Manually Symptom	UMLS \| Name(Total Manually Symptoms:4) C0400979 \| biliary obstruction C0347016 \| spinal cord metastasis C0032227 \| pleural effusions C0018133 \| graft-versus-host disease
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:3)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1051266	18458567	4524	MTHFR	umls:C0079748	BeFree	We investigated preliminarily whether methylenetetrahydrofolate reductase (MTHFR) 677C/T or reduced folate carrier 1 (RFC1) 80G/A polymorphisms were associated with toxicities during maintenance chemotherapy with mercaptopurine (6MP) and methotrexate (MTX) in children with acute lymphoblastic leukemia or lymphoblastic lymphoma.	0.000542884	2008	SLC19A1	21	45537880	T	C
rs368087026	18458567	4524	MTHFR	umls:C0079748	BeFree	We investigated preliminarily whether methylenetetrahydrofolate reductase (MTHFR) 677C/T or reduced folate carrier 1 (RFC1) 80G/A polymorphisms were associated with toxicities during maintenance chemotherapy with mercaptopurine (6MP) and methotrexate (MTX) in children with acute lymphoblastic leukemia or lymphoblastic lymphoma.	0.000542884	2008	SLC19A1	21	45530890	G	A
rs386514057	18458567	4524	MTHFR	umls:C0079748	BeFree	We investigated preliminarily whether methylenetetrahydrofolate reductase (MTHFR) 677C/T or reduced folate carrier 1 (RFC1) 80G/A polymorphisms were associated with toxicities during maintenance chemotherapy with mercaptopurine (6MP) and methotrexate (MTX) in children with acute lymphoblastic leukemia or lymphoblastic lymphoma.	0.000542884	2008	NA	NA	NA	NA	NA

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:0)
(Waiting for update.)

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

Web
Analytics