PedAM

Pediatric Disease Annotations & Medicines


	leukemia

Disease ID	538
Disease	leukemia
Definition	A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
Synonym	#NAME? [m]leukaemia nos [m]leukaemia nos (disorder) [m]leukaemia unspecified, nos [m]leukaemias unspecified [m]leukemia nos [m]leukemia nos (morphologic abnormality) [m]leukemia unspecified, nos [m]leukemia unspecified, nos (morphologic abnormality) [m]leukemias unspecified [m]leukemias unspecified (morphologic abnormality) aleukaemic leukaemia [obs] aleukemic leukemia [obs] all types of leukemia blood (leukemia) chronic leukaemia [obs] chronic leukemia [obs] leucocythaemia leucocythaemias leucocythemia leucocythemias leukaemia leukaemia morphology leukaemia nos leukaemia of unspecified cell type leukaemia of unspecified cell type (disorder) leukaemia, disease leukaemia, no icd-o subtype leukaemia, nos leukaemia, nos, without mention of remission leukaemias leukemia (disorder) leukemia [disease/finding] leukemia morphology leukemia nos leukemia nos (disorder) leukemia of unspecified cell type leukemia of unspecified cell type (disorder) leukemia type leukemia types leukemia, disease leukemia, disease (disorder) leukemia, malignant leukemia, morphology (morphologic abnormality) leukemia, no icd-o subtype leukemia, no icd-o subtype (morphologic abnormality) leukemia, no international classification of diseases for oncology subtype leukemia, no international classification of diseases for oncology subtype (morphologic abnormality) leukemia, nos leukemia, nos, without mention of remission leukemias leukemias types leukemias, general subacute leukaemia [obs] subacute leukemia [obs] type leukemia types leukemia unspecified leukemia
DOID	DOID:1240
UMLS	C0023418
MeSH	D007938
SNOMED-CT	SNOMEDCT_US_2016_09_01:93143009
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:356) C0026985 \| myelodysplasia \| 32 C0024299 \| lymphoma \| 26 C0026986 \| myelodysplastic syndrome \| 21 C1261473 \| sarcoma \| 16 C0027947 \| neutropenia \| 14 C0040034 \| thrombocytopenia \| 13 C0023470 \| myeloid leukemia \| 13 C0023434 \| chronic lymphocytic leukemia \| 12 C0019158 \| hepatitis \| 11 C0026764 \| multiple myeloma \| 11 C0023467 \| acute myeloid leukemia \| 11 C0040053 \| thrombosis \| 10 C0026946 \| fungal infection \| 10 C0023448 \| lymphocytic leukemia \| 10 C0002871 \| anemia \| 10 C0042769 \| virus infection \| 9 C0035078 \| renal failure \| 9 C0023473 \| chronic myeloid leukemia \| 9 C0023449 \| acute lymphoblastic leukemia \| 9 C0026764 \| myeloma \| 8 C0004030 \| aspergillosis \| 8 C0152276 \| myeloid sarcoma \| 8 C0013080 \| trisomy 21 \| 8 C0001815 \| myelofibrosis \| 7 C0011847 \| diabetes \| 7 C0030312 \| pancytopenia \| 7 C0002878 \| hemolytic anemia \| 7 C0152276 \| granulocytic sarcoma \| 6 C0023448 \| lymphoblastic leukemia \| 6 C0012739 \| disseminated intravascular coagulation \| 6 C0598894 \| monocytic leukemia \| 6 C0024299 \| lymphomas \| 6 C0026946 \| fungal infections \| 5 C0032285 \| pneumonia \| 5 C0376358 \| prostate cancer \| 5 C0022660 \| acute renal failure \| 5 C0026986 \| myelodysplastic syndromes \| 5 C0028754 \| obesity \| 5 C0152276 \| chloroma \| 5 C0376545 \| hematologic malignancies \| 5 C0024899 \| mastocytosis \| 5 C0002880 \| autoimmune hemolytic anemia \| 5 C0006142 \| breast cancer \| 5 C0023487 \| acute promyelocytic leukemia \| 4 C0023470 \| myelogenous leukemia \| 4 C0019829 \| hodgkin's lymphoma \| 4 C0001125 \| lactic acidosis \| 4 C0024291 \| hemophagocytic lymphohistiocytosis \| 4 C0041296 \| tuberculosis \| 4 C0003873 \| rheumatoid arthritis \| 4 C0040028 \| essential thrombocythemia \| 4 C0026946 \| fungal disease \| 4 C0221013 \| systemic mastocytosis \| 4 C0020437 \| hypercalcemia \| 4 C0026718 \| mucormycosis \| 4 C0079731 \| b-cell lymphoma \| 4 C0030312 \| bone marrow failure \| 3 C0021400 \| influenza \| 3 C0334634 \| mantle cell lymphoma \| 3 C0019196 \| hepatitis c \| 3 C0272286 \| immune thrombocytopenia \| 3 C0012739 \| disseminated intravascular coagulation (dic) \| 3 C0004623 \| bacterial infection \| 3 C0008625 \| chromosomal abnormality \| 3 C0019829 \| hodgkin lymphoma \| 3 C0011849 \| diabetes mellitus \| 3 C0011848 \| diabetes insipidus \| 3 C0030305 \| pancreatitis \| 3 C0376545 \| hematological malignancy \| 3 C0042769 \| viral infection \| 3 C0003864 \| arthritis \| 3 C0003615 \| appendicitis \| 3 C0281963 \| red cell aplasia \| 3 C0042384 \| vasculitis \| 3 C0023473 \| chronic myelogenous leukemia \| 3 C0029443 \| osteomyelitis \| 3 C0085113 \| neurofibromatosis \| 3 C0023443 \| hairy cell leukemia \| 3 C0034902 \| pure red cell aplasia \| 3 C0019163 \| hepatitis b \| 3 C0085293 \| hepatitis e \| 3 C0011570 \| depression \| 3 C0085110 \| severe combined immunodefic \| 2 C0041327 \| pulmonary tuberculosis \| 2 C0037198 \| sinus thrombosis \| 2 C0442874 \| neuropathy \| 2 C0024305 \| non-hodgkin lymphoma \| 2 C0016085 \| filariasis \| 2 C0024314 \| lymphoproliferative disorder \| 2 C0025202 \| melanoma \| 2 C0004936 \| mental disorders \| 2 C0030807 \| pemphigus \| 2 C0023470 \| myelocytic leukemia \| 2 C0025289 \| meningitis \| 2 C0035305 \| retinal detachment \| 2 C0027022 \| myeloproliferative neoplasms \| 2 C0836924 \| thrombocytosis \| 2 C0001418 \| adenocarcinoma \| 2 C0024790 \| paroxysmal nocturnal hemoglobinuria \| 2 C0015625 \| fanconi anemia \| 2 C0007137 \| squamous cell carcinoma \| 2 C0010346 \| crohn's disease \| 2 C0027121 \| myositis \| 2 C0020456 \| hyperglycemia \| 2 C0031069 \| familial mediterranean fever \| 2 C0238198 \| gastrointestinal stromal tumor \| 2 C0085693 \| acute appendicitis \| 2 C0024291 \| hemophagocytic syndrome \| 2 C0879615 \| stromal tumor \| 2 C0079744 \| diffuse large b-cell lymphoma \| 2 C0023487 \| promyelocytic leukemia \| 2 C1261473 \| sarcomas \| 2 C0085110 \| severe combined immunodeficiency \| 2 C0024305 \| non-hodgkin's lymphoma \| 2 C0034150 \| purpura \| 2 C0021053 \| immune disease \| 2 C0033975 \| psychosis \| 2 C0026896 \| myasthenia gravis \| 2 C0686377 \| cns metastasis \| 2 C1568868 \| oral mucositis \| 2 C0039446 \| telangiectasia \| 2 C1522378 \| large granular lymphocytosis \| 2 C0011860 \| type 2 diabetes \| 2 C0001815 \| bone marrow fibrosis \| 2 C0007570 \| celiac disease \| 2 C0349631 \| richter's syndrome \| 2 C0008049 \| varicella \| 2 C0079748 \| lymphoblastic lymphoma \| 2 C0015230 \| rash \| 2 C0035333 \| retinitis \| 2 C0026764 \| plasma cell myeloma \| 2 C0343386 \| clostridium difficile infection \| 2 C0004623 \| bacterial infections \| 2 C0009319 \| colitis \| 2 C0085669 \| acute leukemia \| 2 C0011991 \| diarrhea \| 2 C0027819 \| neuroblastoma \| 1 C0022116 \| ischemia \| 1 C0021053 \| immune disorder \| 1 C0878544 \| myocardial disease \| 1 C0042769 \| viral infections \| 1 C0014038 \| encephalitis \| 1 C0206644 \| fibrous histiocytoma \| 1 C0010414 \| cryptococcus neoformans \| 1 C0009402 \| colorectal cancer \| 1 C0024312 \| lymphopenia \| 1 C0023434 \| b-cell chronic lymphocytic leukemia \| 1 C0022972 \| myasthenic syndrome \| 1 C0014236 \| endophthalmitis \| 1 C0010346 \| crohn disease \| 1 C0018801 \| cardiac failure \| 1 C0024899 \| mast cell disease \| 1 C0015464 \| facial palsy \| 1 C0155626 \| acute mi \| 1 C0006285 \| bronchopneumonia \| 1 C0242379 \| lung cancer \| 1 C0206686 \| adrenocortical carcinoma \| 1 C0206178 \| cmv retinitis \| 1 C0006840 \| candida infection \| 1 C0002874 \| aplastic anemia \| 1 C0080032 \| malignant pleural effusion \| 1 C1336745 \| thymic lymphoma \| 1 C0036220 \| kaposi's sarcoma \| 1 C0026769 \| multiple sclerosis \| 1 C0001824 \| agranulocytosis \| 1 C0004135 \| ataxia telangiectasia \| 1 C0007847 \| cervical cancer \| 1 C1704275 \| pyomyositis \| 1 C0278553 \| recurrent colon cancer \| 1 C0017636 \| glioblastoma \| 1 C0006625 \| cachectic \| 1 C0017205 \| gaucher disease \| 1 C0027708 \| wilms tumor 1 \| 1 C0235974 \| pancreatic cancer \| 1 C0151332 \| active tuberculosis \| 1 C0042721 \| viral hepatitis \| 1 C1704214 \| xanthogranuloma \| 1 C0302592 \| cervical ca \| 1 C0019069 \| hemophilia \| 1 C0035305 \| retinal detachments \| 1 C0376480 \| gingival enlargement \| 1 C0238124 \| necrotizing fasciitis \| 1 C0029456 \| osteoporosis \| 1 C0005818 \| thrombocytopathy \| 1 C0037274 \| dermatoses \| 1 C0004903 \| beckwith-wiedemann syndrome \| 1 C0742472 \| central nervous system lymphoma \| 1 C0004134 \| ataxia \| 1 C0027121 \| inflammatory myopathy \| 1 C0334463 \| malignant fibrous histiocytoma \| 1 C0001430 \| adenoma \| 1 C0002886 \| macrocytic anemia \| 1 C0043119 \| werner syndrome \| 1 C0154830 \| proliferative diabetic retinopathy \| 1 C0042721 \| hepatitis viral \| 1 C0008533 \| factor ix deficiency \| 1 C1153706 \| uterine adenocarcinoma \| 1 C0023290 \| visceral leishmaniasis \| 1 C0018784 \| sensorineural hearing loss \| 1 C0027809 \| schwannoma \| 1 C0020676 \| hypothyroidism \| 1 C0334590 \| anaplastic oligodendroglioma \| 1 C0031117 \| peripheral neuropathy \| 1 C0032587 \| polyradiculoneuropathy \| 1 C0014130 \| endocrinopathy \| 1 C0014541 \| epiglottitis \| 1 C0553580 \| ewing's sarcoma \| 1 C1136085 \| monoclonal gammopathy \| 1 C0272412 \| splenic abscess \| 1 C0023281 \| leishmaniasis \| 1 C0024198 \| borrelia burgdorferi infection \| 1 C0376545 \| hematologic malignancy \| 1 C0000786 \| miscarriage \| 1 C0020541 \| portal hypertension \| 1 C0007117 \| basal cell carcinoma \| 1 C0740394 \| hyperuricemia \| 1 C0012739 \| consumption coagulopathy \| 1 C0220650 \| brain metastasis \| 1 C0079731 \| b-cell lymphomas \| 1 C0242343 \| panhypopituitarism \| 1 C0001206 \| acromegaly \| 1 C0035309 \| retinopathy \| 1 C0023467 \| acute myeloblastic leukemia \| 1 C0025637 \| methemoglobinemia \| 1 C0028326 \| noonan syndrome \| 1 C0007102 \| colon cancer \| 1 C0010418 \| cryptosporidiosis \| 1 C0085253 \| adult-onset still's disease \| 1 C0024115 \| pulmonary disease \| 1 C0024454 \| maffucci syndrome \| 1 C0023493 \| human t cell leukemia \| 1 C0153567 \| uterine cancer \| 1 C0011860 \| type 2 diabetes mellitus \| 1 C0011603 \| dermatitis \| 1 C0265210 \| weaver syndrome \| 1 C0026848 \| myopathy \| 1 C0035328 \| retinal vein occlusion \| 1 C0553662 \| juvenile idiopathic arthritis \| 1 C1302547 \| chronic lymphocytic leukemia/small lymphocytic lymphoma \| 1 C0028945 \| oligodendrogliomas \| 1 C0035412 \| rhabdomyosarcoma \| 1 C0020550 \| hyperthyroidism \| 1 C0878544 \| cardiomyopathy \| 1 C1619734 \| pulmonary arterial hypertension \| 1 C1527336 \| sjogren's syndrome \| 1 C0010414 \| cryptococcosis \| 1 C0017601 \| glaucoma \| 1 C0032357 \| poland syndrome \| 1 C0002173 \| follicular mucinosis \| 1 C0043117 \| immune thrombocytopenic purpura \| 1 C1136084 \| plasma cell dyscrasia \| 1 C0079419 \| li-fraumeni syndrome \| 1 C0027051 \| myocardial infarction \| 1 C0039103 \| synovitis \| 1 C0002991 \| dermatofibroma \| 1 C0011884 \| diabetic retinopathy \| 1 C0039730 \| thalassemia \| 1 C0007642 \| cellulitis \| 1 C0025309 \| meningoencephalitis \| 1 C0151744 \| myocardial ischemia \| 1 C0024214 \| lymphangiectasia \| 1 C0009806 \| constipation \| 1 C0023798 \| lipomas \| 1 C0085160 \| hidradenitis \| 1 C0038034 \| sporotrichosis \| 1 C0027708 \| wilms' tumor \| 1 C0024796 \| marfan's syndrome \| 1 C0036421 \| systemic sclerosis \| 1 C0032371 \| poliomyelitis \| 1 C0027022 \| myeloproliferative disorder \| 1 C0019621 \| langerhans cell histiocytosis \| 1 C0021053 \| immune dysfunction \| 1 C0023434 \| small lymphocytic lymphoma \| 1 C0015645 \| fasciitis \| 1 C0017551 \| gilbert's syndrome \| 1 C0007129 \| merkel cell carcinoma \| 1 C0152013 \| lung adenocarcinoma \| 1 C0238190 \| inclusion body myositis \| 1 C0026986 \| preleukemia \| 1 C0155626 \| acute myocardial infarction \| 1 C1704437 \| respiratory distress syndrome \| 1 C0008325 \| cholecystitis \| 1 C0040128 \| thyroid disease \| 1 C0006840 \| candidiasis \| 1 C1368107 \| bone marrow aplasia \| 1 C0002726 \| amyloidosis \| 1 C0027051 \| myocardial infarct \| 1 C0026277 \| pleomorphic adenoma \| 1 C0019348 \| herpes simplex \| 1 C0238198 \| gastrointestinal stromal tumors \| 1 C0241910 \| autoimmune hepatitis \| 1 C0017205 \| gaucher's disease \| 1 C0011860 \| diabetes mellitus type 2 \| 1 C0039538 \| teratoma \| 1 C0028866 \| oculomotor nerve palsy \| 1 C0036202 \| sarcoidosis \| 1 C0154841 \| central retinal vein occlusion \| 1 C0031485 \| phenylketonuria \| 1 C0024198 \| lyme disease \| 1 C0155550 \| neural deafness \| 1 C0007131 \| nsclc \| 1 C0279626 \| esophageal squamous cell carcinoma \| 1 C0008513 \| retinochoroiditis \| 1 C0007959 \| charcot-marie-tooth disease \| 1 C0014118 \| endocarditis \| 1 C0033680 \| protein-losing enteropathy \| 1 C1509147 \| histiocytoma \| 1 C0155773 \| portal vein thrombosis \| 1 C0023467 \| acute myelogenous leukemia \| 1 C0854750 \| recurrent colorectal cancer \| 1 C0007113 \| rectal cancer \| 1 C0836924 \| thrombocythemia \| 1 C0751606 \| adult all \| 1 C0004943 \| behcet's disease \| 1 C0022735 \| klinefelter's syndrome \| 1 C0037199 \| sinusitis \| 1 C0020538 \| hypertension \| 1 C0019048 \| hemoglobinuria \| 1 C0015469 \| facial nerve paralysis \| 1 C0038013 \| ankylosing spondylitis \| 1 C0282193 \| iron overload \| 1 C0009324 \| ulcerative colitis \| 1 C0017665 \| membranous nephropathy \| 1 C0018801 \| heart failure \| 1 C0021053 \| immune disorders \| 1 C0043541 \| zygomycosis \| 1 C0242006 \| secondary myelofibrosis \| 1 C0007137 \| squamous cell carcinomas \| 1 C0027708 \| wilms tumor \| 1 C0023484 \| plasma cell leukemia \| 1 C0018854 \| franklin disease \| 1 C0015674 \| chronic fatigue syndrome \| 1 C1621958 \| glioblastoma multiforme \| 1 C0027022 \| myeloproliferative disorders \| 1 C0023465 \| acute monocytic leukemia \| 1 C1260325 \| follicular dendritic cell sarcoma \| 1 C0035304 \| retinal degeneration \| 1 C0010403 \| cryoglobulinemia \| 1 C0019360 \| zoster \| 1 C0032285 \| pneumonitis \| 1 C0015773 \| felty syndrome \| 1 C0033860 \| psoriasis \| 1 C0687720 \| central diabetes insipidus \| 1 C0679466 \| cognitive deficits \| 1 C0700594 \| radiculopathy \| 1 C0024314 \| lymphoproliferative disorders \| 1 C0024141 \| systemic lupus erythematosus \| 1 C0007114 \| skin cancer \| 1 C0022972 \| lambert-eaton myasthenic syndrome \| 1 C0600139 \| prostate carcinoma \| 1 C0018784 \| sensorineural deafness \| 1 C0029132 \| optic neuropathy \| 1 C0409974 \| lupus erythematosus \| 1 C0003467 \| anxiety \| 1 C0018418 \| gynaecomastia \| 1 C0015624 \| fanconi syndrome \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:38) STAT5B \| 6777 \| GHR PTPN11 \| 5781 \| CTD_human PRAME \| 23532 \| CTD_human CCND1 \| 595 \| CTD_human WT1 \| 7490 \| CTD_human TOP2A \| 7153 \| CTD_human TNFSF10 \| 8743 \| CTD_human ESR1 \| 2099 \| CTD_human HP \| 3240 \| CTD_human PTEN \| 5728 \| CTD_human SMPD3 \| 55512 \| CTD_human KMT2A \| 4297 \| CTD_human JAK2 \| 3717 \| CTD_human RARA \| 5914 \| GHR AR \| 367 \| CTD_human IL2 \| 3558 \| CTD_human NUMA1 \| 4926 \| GHR GSTM1 \| 2944 \| CTD_human KMT2E \| 55904 \| CTD_human BIRC3 \| 330 \| CTD_human GSTO1 \| 9446 \| CTD_human ZBTB16 \| 7704 \| GHR DDIT4 \| 54541 \| CTD_human MGMT \| 4255 \| CTD_human SETD2 \| 29072 \| CTD_human PML \| 5371 \| GHR FGF1 \| 2246 \| CTD_human CFLAR \| 8837 \| CTD_human NCOA3 \| 8202 \| CTD_human NPM1 \| 4869 \| GHR ERG \| 2078 \| CTD_human PRKCZ \| 5590 \| CTD_human FOXM1 \| 2305 \| CTD_human BIRC2 \| 329 \| CTD_human BAD \| 572 \| CTD_human SPHK1 \| 8877 \| CTD_human PPP1R13L \| 10848 \| CTD_human AQP9 \| 366 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:116) 5243 \| ABCB1 \| infer 25 \| ABL1 \| infer 28 \| ABO \| infer 1636 \| ACE \| infer 328 \| APEX1 \| infer 84159 \| ARID5B \| infer 115761 \| ARL11 \| infer 10550 \| ARL6IP5 \| infer 472 \| ATM \| infer 581 \| BAX \| infer 596 \| BCL2 \| infer 613 \| BCR \| infer 847 \| CAT \| infer 865 \| CBFB \| infer 595 \| CCND1 \| infer 921 \| CD5 \| infer 1026 \| CDKN1A \| infer 1027 \| CDKN1B \| infer 1029 \| CDKN2A \| infer 1030 \| CDKN2B \| infer 1053 \| CEBPE \| infer 80781 \| COL18A1 \| infer 64506 \| CPEB1 \| infer 1543 \| CYP1A1 \| infer 1565 \| CYP2D6 \| infer 1571 \| CYP2E1 \| infer 1576 \| CYP3A4 \| infer 1577 \| CYP3A5 \| infer 1633 \| DCK \| infer 1672 \| DEFB1 \| infer 1719 \| DHFR \| infer 2067 \| ERCC1 \| infer 2068 \| ERCC2 \| infer 2073 \| ERCC5 \| infer 9855 \| FARP2 \| infer 55294 \| FBXW7 \| infer 2214 \| FCGR3A \| infer 2322 \| FLT3 \| infer 50943 \| FOXP3 \| infer 2778 \| GNAS \| infer 2944 \| GSTM1 \| infer 2950 \| GSTP1 \| infer 2952 \| GSTT1 \| infer 3077 \| HFE \| infer 3006 \| HIST1H1C \| infer 3010 \| HIST1H1T \| infer 3105 \| HLA-A \| infer 3106 \| HLA-B \| infer 3107 \| HLA-C \| infer 3115 \| HLA-DPB1 \| infer 3117 \| HLA-DQA1 \| infer 3119 \| HLA-DQB1 \| infer 3123 \| HLA-DRB1 \| infer 3126 \| HLA-DRB4 \| infer 3303 \| HSPA1A \| infer 3304 \| HSPA1B \| infer 3305 \| HSPA1L \| infer 3458 \| IFNG \| infer 10320 \| IKZF1 \| infer 3586 \| IL10 \| infer 3565 \| IL4 \| infer 3662 \| IRF4 \| infer 3717 \| JAK2 \| infer 3802 \| KIR2DL1 \| infer 3803 \| KIR2DL2 \| infer 3804 \| KIR2DL3 \| infer 3805 \| KIR2DL4 \| infer 57292 \| KIR2DL5A \| infer 553128 \| KIR2DL5B \| infer 554300 \| KIR2DP1 \| infer 3806 \| KIR2DS1 \| infer 100132285 \| KIR2DS2 \| infer 3808 \| KIR2DS3 \| infer 3809 \| KIR2DS4 \| infer 3810 \| KIR2DS5 \| infer 3811 \| KIR3DL1 \| infer 3812 \| KIR3DL2 \| infer 115653 \| KIR3DL3 \| infer 548594 \| KIR3DP1 \| infer 3813 \| KIR3DS1 \| infer 3815 \| KIT \| infer 4137 \| MAPT \| infer 4193 \| MDM2 \| infer 4255 \| MGMT \| infer 4292 \| MLH1 \| infer 4353 \| MPO \| infer 4436 \| MSH2 \| infer 4437 \| MSH3 \| infer 4522 \| MTHFD1 \| infer 4524 \| MTHFR \| infer 4548 \| MTR \| infer 4552 \| MTRR \| infer 4629 \| MYH11 \| infer 4683 \| NBN \| infer 4851 \| NOTCH1 \| infer 4869 \| NPM1 \| infer 1728 \| NQO1 \| infer 5027 \| P2RX7 \| infer 5371 \| PML \| infer 5888 \| RAD51 \| infer 861 \| RUNX1 \| infer 6580 \| SLC22A1 \| infer 6648 \| SOD2 \| infer 6821 \| SUOX \| infer 54790 \| TET2 \| infer 7040 \| TGFB1 \| infer 7157 \| TP53 \| infer 7172 \| TPMT \| infer 7298 \| TYMS \| infer 54658 \| UGT1A1 \| infer 7421 \| VDR \| infer 7515 \| XRCC1 \| infer 7516 \| XRCC2 \| infer 7517 \| XRCC3 \| infer 7518 \| XRCC4 \| infer 7704 \| ZBTB16 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:2108) 8847 \| DLEU2 \| DISEASES 102725541 \| ELDR \| DISEASES 2288 \| FKBP4 \| DISEASES 5898 \| RALA \| DISEASES 3207 \| HOXA11 \| DISEASES 4706 \| NDUFAB1 \| DISEASES 1407 \| CRY1 \| DISEASES 928 \| CD9 \| DISEASES 972 \| CD74 \| DISEASES 920 \| CD4 \| DISEASES 4830 \| NME1 \| DISEASES 11183 \| MAP4K5 \| DISEASES 2067 \| ERCC1 \| DISEASES 10928 \| RALBP1 \| DISEASES 1015 \| CDH17 \| DISEASES 3224 \| HOXC8 \| DISEASES 3937 \| LCP2 \| DISEASES 608 \| TNFRSF17 \| DISEASES 54432 \| YIPF1 \| DISEASES 51564 \| HDAC7 \| DISEASES 933 \| CD22 \| DISEASES 28951 \| TRIB2 \| DISEASES 3385 \| ICAM3 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 602 \| BCL3 \| DISEASES 57595 \| PDZD4 \| DISEASES 10272 \| FSTL3 \| DISEASES 3566 \| IL4R \| DISEASES 9817 \| KEAP1 \| DISEASES 7145 \| TNS1 \| DISEASES 4804 \| NGFR \| DISEASES 440 \| ASNS \| DISEASES 30009 \| TBX21 \| DISEASES 54763 \| ROPN1 \| DISEASES 4680 \| CEACAM6 \| DISEASES 23645 \| PPP1R15A \| DISEASES 6820 \| SULT2B1 \| DISEASES 28954 \| REM1 \| DISEASES 3902 \| LAG3 \| DISEASES 8079 \| MLF2 \| DISEASES 7066 \| THPO \| DISEASES 2099 \| ESR1 \| DISEASES 1053 \| CEBPE \| DISEASES 23468 \| CBX5 \| DISEASES 7414 \| VCL \| DISEASES 23411 \| SIRT1 \| DISEASES 7593 \| MZF1 \| DISEASES 9524 \| TECR \| DISEASES 4616 \| GADD45B \| DISEASES 4320 \| MMP11 \| DISEASES 4282 \| MIF \| DISEASES 5008 \| OSM \| DISEASES 11274 \| USP18 \| DISEASES 5594 \| MAPK1 \| DISEASES 6948 \| TCN2 \| DISEASES 3956 \| LGALS1 \| DISEASES 79019 \| CENPM \| DISEASES 7494 \| XBP1 \| DISEASES 638 \| BIK \| DISEASES 3162 \| HMOX1 \| DISEASES 4627 \| MYH9 \| DISEASES 158 \| ADSL \| DISEASES 6767 \| ST13 \| DISEASES 3560 \| IL2RB \| DISEASES 23774 \| BRD1 \| DISEASES 11035 \| RIPK3 \| DISEASES 1511 \| CTSG \| DISEASES 3002 \| GZMB \| DISEASES 4792 \| NFKBIA \| DISEASES 6790 \| AURKA \| DISEASES 4605 \| MYBL2 \| DISEASES 57167 \| SALL4 \| DISEASES 79444 \| BIRC7 \| DISEASES 1457 \| CSNK2A1 \| DISEASES 191 \| AHCY \| DISEASES 6880 \| TAF9 \| DISEASES 51311 \| TLR8 \| DISEASES 10735 \| STAG2 \| DISEASES 63035 \| BCORL1 \| DISEASES 7076 \| TIMP1 \| DISEASES 54 \| ACP5 \| DISEASES 4313 \| MMP2 \| DISEASES 11151 \| CORO1A \| DISEASES 6367 \| CCL22 \| DISEASES 6361 \| CCL17 \| DISEASES 4832 \| NME3 \| DISEASES 10273 \| STUB1 \| DISEASES 3163 \| HMOX2 \| DISEASES 4150 \| MAZ \| DISEASES 366 \| AQP9 \| DISEASES 1445 \| CSK \| DISEASES 55824 \| PAG1 \| DISEASES 1666 \| DECR1 \| DISEASES 6422 \| SFRP1 \| DISEASES 5327 \| PLAT \| DISEASES 9694 \| EMC2 \| DISEASES 8797 \| TNFRSF10A \| DISEASES 4849 \| CNOT3 \| DISEASES 56915 \| EXOSC5 \| DISEASES 27294 \| DHDH \| DISEASES 1891 \| ECH1 \| DISEASES 3191 \| HNRNPL \| DISEASES 5971 \| RELB \| DISEASES 10535 \| RNASEH2A \| DISEASES 2091 \| FBL \| DISEASES 10148 \| EBI3 \| DISEASES 7040 \| TGFB1 \| DISEASES 973 \| CD79A \| DISEASES 1048 \| CEACAM5 \| DISEASES 11140 \| CDC37 \| DISEASES 2057 \| EPOR \| DISEASES 2077 \| ERF \| DISEASES 3082 \| HGF \| DISEASES 51384 \| WNT16 \| DISEASES 3199 \| HOXA2 \| DISEASES 3202 \| HOXA5 \| DISEASES 3203 \| HOXA6 \| DISEASES 3209 \| HOXA13 \| DISEASES 1577 \| CYP3A5 \| DISEASES 5054 \| SERPINE1 \| DISEASES 93408 \| MYL10 \| DISEASES 51510 \| CHMP5 \| DISEASES 944 \| TNFSF8 \| DISEASES 7431 \| VIM \| DISEASES 29760 \| BLNK \| DISEASES 1592 \| CYP26A1 \| DISEASES 6348 \| CCL3 \| DISEASES 4353 \| MPO \| DISEASES 5026 \| P2RX5 \| DISEASES 8288 \| EPX \| DISEASES 1440 \| CSF3 \| DISEASES 6198 \| RPS6KB1 \| DISEASES 10951 \| CBX1 \| DISEASES 3216 \| HOXB6 \| DISEASES 708 \| C1QBP \| DISEASES 6347 \| CCL2 \| DISEASES 2648 \| KAT2A \| DISEASES 3131 \| HLF \| DISEASES 7448 \| VTN \| DISEASES 952 \| CD38 \| DISEASES 173 \| AFM \| DISEASES 4790 \| NFKB1 \| DISEASES 3558 \| IL2 \| DISEASES 3732 \| CD82 \| DISEASES 6688 \| SPI1 \| DISEASES 3312 \| HSPA8 \| DISEASES 6484 \| ST3GAL4 \| DISEASES 595 \| CCND1 \| DISEASES 329 \| BIRC2 \| DISEASES 4254 \| KITLG \| DISEASES 10795 \| ZNF268 \| DISEASES 5829 \| PXN \| DISEASES 969 \| CD69 \| DISEASES 6404 \| SELPLG \| DISEASES 2735 \| GLI1 \| DISEASES 80824 \| DUSP16 \| DISEASES 1389 \| CREBL2 \| DISEASES 1027 \| CDKN1B \| DISEASES 55507 \| GPRC5D \| DISEASES 397 \| ARHGDIB \| DISEASES 3458 \| IFNG \| DISEASES 2597 \| GAPDH \| DISEASES 2026 \| ENO2 \| DISEASES 79923 \| NANOG \| DISEASES 55907 \| CMAS \| DISEASES 57379 \| AICDA \| DISEASES 26127 \| FGFR1OP2 \| DISEASES 3820 \| KLRB1 \| DISEASES 80329 \| ULBP1 \| DISEASES 1432 \| MAPK14 \| DISEASES 2822 \| GPLD1 \| DISEASES 6908 \| TBP \| DISEASES 5754 \| PTK7 \| DISEASES 6534 \| SLC6A7 \| DISEASES 1611 \| DAP \| DISEASES 4015 \| LOX \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 7903 \| ST8SIA4 \| DISEASES 6500 \| SKP1 \| DISEASES 9631 \| NUP155 \| DISEASES 2908 \| NR3C1 \| DISEASES 5917 \| RARS \| DISEASES 1044 \| CDX1 \| DISEASES 4292 \| MLH1 \| DISEASES 51185 \| CRBN \| DISEASES 604 \| BCL6 \| DISEASES 80325 \| ABTB1 \| DISEASES 26528 \| DAZAP1 \| DISEASES 4436 \| MSH2 \| DISEASES 7035 \| TFPI \| DISEASES 1796 \| DOK1 \| DISEASES 3485 \| IGFBP2 \| DISEASES 3554 \| IL1R1 \| DISEASES 3398 \| ID2 \| DISEASES 4953 \| ODC1 \| DISEASES 10153 \| CEBPZ \| DISEASES 5341 \| PLEK \| DISEASES 5657 \| PRTN3 \| DISEASES 2956 \| MSH6 \| DISEASES 607 \| BCL9 \| DISEASES 7799 \| PRDM2 \| DISEASES 11126 \| CD160 \| DISEASES 6402 \| SELL \| DISEASES 1509 \| CTSD \| DISEASES 471 \| ATIC \| DISEASES 7128 \| TNFAIP3 \| DISEASES 9429 \| ABCG2 \| DISEASES 22936 \| ELL2 \| DISEASES 2745 \| GLRX \| DISEASES 112752 \| IFT43 \| DISEASES 3218 \| HOXB8 \| DISEASES 3217 \| HOXB7 \| DISEASES 1843 \| DUSP1 \| DISEASES 5396 \| PRRX1 \| DISEASES 84955 \| NUDCD1 \| DISEASES 4360 \| MRC1 \| DISEASES 8600 \| TNFSF11 \| DISEASES 1997 \| ELF1 \| DISEASES 1958 \| EGR1 \| DISEASES 4801 \| NFYB \| DISEASES 7976 \| FZD3 \| DISEASES 1748 \| DLX4 \| DISEASES 2703 \| GJA8 \| DISEASES 847 \| CAT \| DISEASES 8743 \| TNFSF10 \| DISEASES 2322 \| FLT3 \| DISEASES 3204 \| HOXA7 \| DISEASES 27434 \| POLM \| DISEASES 7291 \| TWIST1 \| DISEASES 5552 \| SRGN \| DISEASES 1959 \| EGR2 \| DISEASES 3229 \| HOXC13 \| DISEASES 140690 \| CTCFL \| DISEASES 5266 \| PI3 \| DISEASES 5335 \| PLCG1 \| DISEASES 6431 \| SRSF6 \| DISEASES 5184 \| PEPD \| DISEASES 1088 \| CEACAM8 \| DISEASES 1026 \| CDKN1A \| DISEASES 6659 \| SOX4 \| DISEASES 56848 \| SPHK2 \| DISEASES 3659 \| IRF1 \| DISEASES 652 \| BMP4 \| DISEASES 51081 \| MRPS7 \| DISEASES 8744 \| TNFSF9 \| DISEASES 970 \| CD70 \| DISEASES 718 \| C3 \| DISEASES 994 \| CDC25B \| DISEASES 22918 \| CD93 \| DISEASES 57095 \| PITHD1 \| DISEASES 5326 \| PLAGL2 \| DISEASES 7389 \| UROD \| DISEASES 10870 \| HCST \| DISEASES 1236 \| CCR7 \| DISEASES 83596 \| BCL2L12 \| DISEASES 51119 \| SBDS \| DISEASES 821 \| CANX \| DISEASES 10365 \| KLF2 \| DISEASES 83460 \| EMC6 \| DISEASES 7429 \| VIL1 \| DISEASES 3315 \| HSPB1 \| DISEASES 7538 \| ZFP36 \| DISEASES 2678 \| GGT1 \| DISEASES 2952 \| GSTT1 \| DISEASES 5880 \| RAC2 \| DISEASES 3976 \| LIF \| DISEASES 22933 \| SIRT2 \| DISEASES 8554 \| PIAS1 \| DISEASES 8773 \| SNAP23 \| DISEASES 54567 \| DLL4 \| DISEASES 8854 \| ALDH1A2 \| DISEASES 4654 \| MYOD1 \| DISEASES 968 \| CD68 \| DISEASES 6351 \| CCL4 \| DISEASES 6320 \| CLEC11A \| DISEASES 599 \| BCL2L2 \| DISEASES 112399 \| EGLN3 \| DISEASES 4738 \| NEDD8 \| DISEASES 3630 \| INS \| DISEASES 5894 \| RAF1 \| DISEASES 2006 \| ELN \| DISEASES 4695 \| NDUFA2 \| DISEASES 4277 \| MICB \| DISEASES 10912 \| GADD45G \| DISEASES 83483 \| PLVAP \| DISEASES 684 \| BST2 \| DISEASES 4298 \| MLLT1 \| DISEASES 2056 \| EPO \| DISEASES 3727 \| JUND \| DISEASES 9253 \| NUMBL \| DISEASES 1571 \| CYP2E1 \| DISEASES 3050 \| HBZ \| DISEASES 3110 \| MNX1 \| DISEASES 445 \| ASS1 \| DISEASES 10155 \| TRIM28 \| DISEASES 55422 \| ZNF331 \| DISEASES 9113 \| LATS1 \| DISEASES 51659 \| GINS2 \| DISEASES 51132 \| RLIM \| DISEASES 8572 \| PDLIM4 \| DISEASES 5914 \| RARA \| DISEASES 2521 \| FUS \| DISEASES 8431 \| NR0B2 \| DISEASES 79727 \| LIN28A \| DISEASES 113 \| ADCY7 \| DISEASES 3958 \| LGALS3 \| DISEASES 6382 \| SDC1 \| DISEASES 8864 \| PER2 \| DISEASES 23135 \| KDM6B \| DISEASES 7014 \| TERF2 \| DISEASES 182 \| JAG1 \| DISEASES 29107 \| NXT1 \| DISEASES 1401 \| CRP \| DISEASES 8900 \| CCNA1 \| DISEASES 28992 \| MACROD1 \| DISEASES 694 \| BTG1 \| DISEASES 3845 \| KRAS \| DISEASES 759 \| CA1 \| DISEASES 1965 \| EIF2S1 \| DISEASES 8932 \| MBD2 \| DISEASES 891 \| CCNB1 \| DISEASES 1022 \| CDK7 \| DISEASES 4064 \| CD180 \| DISEASES 10752 \| CHL1 \| DISEASES 4853 \| NOTCH2 \| DISEASES 80263 \| TRIM45 \| DISEASES 377 \| ARF3 \| DISEASES 10599 \| SLCO1B1 \| DISEASES 6947 \| TCN1 \| DISEASES 5156 \| PDGFRA \| DISEASES 301 \| ANXA1 \| DISEASES 8739 \| HRK \| DISEASES 1840 \| DTX1 \| DISEASES 9883 \| POM121 \| DISEASES 29969 \| MDFIC \| DISEASES 60468 \| BACH2 \| DISEASES 4907 \| NT5E \| DISEASES 4005 \| LMO2 \| DISEASES 967 \| CD63 \| DISEASES 1019 \| CDK4 \| DISEASES 9700 \| ESPL1 \| DISEASES 27429 \| HTRA2 \| DISEASES 160428 \| ALDH1L2 \| DISEASES 55213 \| RCBTB1 \| DISEASES 55270 \| NUDT15 \| DISEASES 3569 \| IL6 \| DISEASES 64005 \| MYO1G \| DISEASES 10241 \| CALCOCO2 \| DISEASES 6426 \| SRSF1 \| DISEASES 11143 \| KAT7 \| DISEASES 640 \| BLK \| DISEASES 3557 \| IL1RN \| DISEASES 2995 \| GYPC \| DISEASES 55363 \| HEMGN \| DISEASES 3442 \| IFNA5 \| DISEASES 26953 \| RANBP6 \| DISEASES 152006 \| RNF38 \| DISEASES 6366 \| CCL21 \| DISEASES 971 \| CD72 \| DISEASES 8870 \| IER3 \| DISEASES 5460 \| POU5F1 \| DISEASES 1208 \| CLPS \| DISEASES 7097 \| TLR2 \| DISEASES 8836 \| GGH \| DISEASES 57569 \| ARHGAP20 \| DISEASES 7057 \| THBS1 \| DISEASES 5330 \| PLCB2 \| DISEASES 10017 \| BCL2L10 \| DISEASES 26160 \| IFT172 \| DISEASES 10113 \| PREB \| DISEASES 9360 \| PPIG \| DISEASES 3417 \| IDH1 \| DISEASES 28234 \| SLCO1B3 \| DISEASES 894 \| CCND2 \| DISEASES 4069 \| LYZ \| DISEASES 5037 \| PEBP1 \| DISEASES 51646 \| YPEL5 \| DISEASES 4001 \| LMNB1 \| DISEASES 7450 \| VWF \| DISEASES 11019 \| LIAS \| DISEASES 55728 \| N4BP2 \| DISEASES 7188 \| TRAF5 \| DISEASES 9097 \| USP14 \| DISEASES 1535 \| CYBA \| DISEASES 23495 \| TNFRSF13B \| DISEASES 999 \| CDH1 \| DISEASES 5159 \| PDGFRB \| DISEASES 904 \| CCNT1 \| DISEASES 2324 \| FLT4 \| DISEASES 57472 \| CNOT6 \| DISEASES 3690 \| ITGB3 \| DISEASES 5289 \| PIK3C3 \| DISEASES 23531 \| MMD \| DISEASES 8427 \| ZNF282 \| DISEASES 9172 \| MYOM2 \| DISEASES 57045 \| TWSG1 \| DISEASES 4087 \| SMAD2 \| DISEASES 3757 \| KCNH2 \| DISEASES 7528 \| YY1 \| DISEASES 945 \| CD33 \| DISEASES 4025 \| LPO \| DISEASES 81671 \| VMP1 \| DISEASES 4591 \| TRIM37 \| DISEASES 8312 \| AXIN1 \| DISEASES 84662 \| GLIS2 \| DISEASES 1387 \| CREBBP \| DISEASES 23090 \| ZNF423 \| DISEASES 3674 \| ITGA2B \| DISEASES 6416 \| MAP2K4 \| DISEASES 9135 \| RABEP1 \| DISEASES 1459 \| CSNK2A2 \| DISEASES 9739 \| SETD1A \| DISEASES 23361 \| ZNF629 \| DISEASES 10483 \| SEC23B \| DISEASES 898 \| CCNE1 \| DISEASES 9139 \| CBFA2T2 \| DISEASES 1031 \| CDKN2C \| DISEASES 22985 \| ACIN1 \| DISEASES 7011 \| TEP1 \| DISEASES 23239 \| PHLPP1 \| DISEASES 7077 \| TIMP2 \| DISEASES 8178 \| ELL \| DISEASES 25939 \| SAMHD1 \| DISEASES 57148 \| RALGAPB \| DISEASES 7515 \| XRCC1 \| DISEASES 2769 \| GNA15 \| DISEASES 6929 \| TCF3 \| DISEASES 51588 \| PIAS4 \| DISEASES 8821 \| INPP4B \| DISEASES 5595 \| MAPK3 \| DISEASES 5264 \| PHYH \| DISEASES 3682 \| ITGAE \| DISEASES 5338 \| PLD2 \| DISEASES 23523 \| CABIN1 \| DISEASES 6598 \| SMARCB1 \| DISEASES 8424 \| BBOX1 \| DISEASES 54487 \| DGCR8 \| DISEASES 11252 \| PACSIN2 \| DISEASES 2033 \| EP300 \| DISEASES 84172 \| POLR1B \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 8726 \| EED \| DISEASES 645 \| BLVRB \| DISEASES 23476 \| BRD4 \| DISEASES 4854 \| NOTCH3 \| DISEASES 3977 \| LIFR \| DISEASES 55717 \| WDR11 \| DISEASES 330 \| BIRC3 \| DISEASES 1820 \| ARID3A \| DISEASES 1991 \| ELANE \| DISEASES 975 \| CD81 \| DISEASES 25884 \| CHRDL2 \| DISEASES 6403 \| SELP \| DISEASES 8850 \| KAT2B \| DISEASES 440275 \| EIF2AK4 \| DISEASES 79968 \| WDR76 \| DISEASES 7301 \| TYRO3 \| DISEASES 4058 \| LTK \| DISEASES 3574 \| IL7 \| DISEASES 55850 \| USE1 \| DISEASES 26511 \| CHIC2 \| DISEASES 3791 \| KDR \| DISEASES 943 \| TNFRSF8 \| DISEASES 5290 \| PIK3CA \| DISEASES 6548 \| SLC9A1 \| DISEASES 10664 \| CTCF \| DISEASES 867 \| CBL \| DISEASES 60482 \| SLC5A7 \| DISEASES 10382 \| TUBB4A \| DISEASES 2208 \| FCER2 \| DISEASES 1716 \| DGUOK \| DISEASES 905 \| CCNT2 \| DISEASES 10874 \| NMU \| DISEASES 941 \| CD80 \| DISEASES 8452 \| CUL3 \| DISEASES 59067 \| IL21 \| DISEASES 2247 \| FGF2 \| DISEASES 5929 \| RBBP5 \| DISEASES 3004 \| GZMM \| DISEASES 3589 \| IL11 \| DISEASES 9759 \| HDAC4 \| DISEASES 7474 \| WNT5A \| DISEASES 7067 \| THRA \| DISEASES 22794 \| CASC3 \| DISEASES 6774 \| STAT3 \| DISEASES 4552 \| MTRR \| DISEASES 2122 \| MECOM \| DISEASES 5443 \| POMC \| DISEASES 1788 \| DNMT3A \| DISEASES 2355 \| FOSL2 \| DISEASES 8626 \| TP63 \| DISEASES 7297 \| TYK2 \| DISEASES 4066 \| LYL1 \| DISEASES 3383 \| ICAM1 \| DISEASES 10661 \| KLF1 \| DISEASES 55722 \| CEP72 \| DISEASES 7535 \| ZAP70 \| DISEASES 80321 \| CEP70 \| DISEASES 683 \| BST1 \| DISEASES 10923 \| SUB1 \| DISEASES 4437 \| MSH3 \| DISEASES 6897 \| TARS \| DISEASES 2028 \| ENPEP \| DISEASES 839 \| CASP6 \| DISEASES 51176 \| LEF1 \| DISEASES 1950 \| EGF \| DISEASES 9061 \| PAPSS1 \| DISEASES 84223 \| IQCG \| DISEASES 56302 \| TRPV5 \| DISEASES 27125 \| AFF4 \| DISEASES 6722 \| SRF \| DISEASES 8829 \| NRP1 \| DISEASES 1390 \| CREM \| DISEASES 5423 \| POLB \| DISEASES 25824 \| PRDX5 \| DISEASES 1998 \| ELF2 \| DISEASES 4986 \| OPRK1 \| DISEASES 54806 \| AHI1 \| DISEASES 1119 \| CHKA \| DISEASES 7994 \| KAT6A \| DISEASES 5244 \| ABCB4 \| DISEASES 5243 \| ABCB1 \| DISEASES 6717 \| SRI \| DISEASES 1021 \| CDK6 \| DISEASES 6595 \| SMARCA2 \| DISEASES 3263 \| HPX \| DISEASES 1616 \| DAXX \| DISEASES 6425 \| SFRP5 \| DISEASES 939 \| CD27 \| DISEASES 11010 \| GLIPR1 \| DISEASES 1017 \| CDK2 \| DISEASES 3695 \| ITGB7 \| DISEASES 5925 \| RB1 \| DISEASES 23067 \| SETD1B \| DISEASES 26277 \| TINF2 \| DISEASES 9321 \| TRIP11 \| DISEASES 51234 \| EMC4 \| DISEASES 2252 \| FGF7 \| DISEASES 3067 \| HDC \| DISEASES 597 \| BCL2A1 \| DISEASES 3480 \| IGF1R \| DISEASES 5371 \| PML \| DISEASES 4240 \| MFGE8 \| DISEASES 5045 \| FURIN \| DISEASES 3687 \| ITGAX \| DISEASES 1039 \| CDR2 \| DISEASES 81631 \| MAP1LC3B \| DISEASES 3394 \| IRF8 \| DISEASES 863 \| CBFA2T3 \| DISEASES 9611 \| NCOR1 \| DISEASES 92579 \| G6PC3 \| DISEASES 1000 \| CDH2 \| DISEASES 7157 \| TP53 \| DISEASES 57332 \| CBX8 \| DISEASES 2064 \| ERBB2 \| DISEASES 6455 \| SH3GL1 \| DISEASES 3454 \| IFNAR1 \| DISEASES 150094 \| SIK1 \| DISEASES 207 \| AKT1 \| DISEASES 5141 \| PDE4A \| DISEASES 63976 \| PRDM16 \| DISEASES 8915 \| BCL10 \| DISEASES 2212 \| FCGR2A \| DISEASES 4209 \| MEF2D \| DISEASES 148327 \| CREB3L4 \| DISEASES 52 \| ACP1 \| DISEASES 375 \| ARF1 \| DISEASES 3930 \| LBR \| DISEASES 7483 \| WNT9A \| DISEASES 2052 \| EPHX1 \| DISEASES 127829 \| ARL8A \| DISEASES 805 \| CALM2 \| DISEASES 4211 \| MEIS1 \| DISEASES 9027 \| NAT8 \| DISEASES 7851 \| MALL \| DISEASES 6769 \| STAC \| DISEASES 10550 \| ARL6IP5 \| DISEASES 8994 \| LIMD1 \| DISEASES 6988 \| TCTA \| DISEASES 55840 \| EAF2 \| DISEASES 890 \| CCNA2 \| DISEASES 80854 \| SETD7 \| DISEASES 6423 \| SFRP2 \| DISEASES 6502 \| SKP2 \| DISEASES 10769 \| PLK2 \| DISEASES 3001 \| GZMA \| DISEASES 5295 \| PIK3R1 \| DISEASES 5921 \| RASA1 \| DISEASES 23092 \| ARHGAP26 \| DISEASES 3578 \| IL9 \| DISEASES 4594 \| MUT \| DISEASES 4794 \| NFKBIE \| DISEASES 134864 \| TAAR1 \| DISEASES 1956 \| EGFR \| DISEASES 7462 \| LAT2 \| DISEASES 2041 \| EPHA1 \| DISEASES 9046 \| DOK2 \| DISEASES 8795 \| TNFRSF10B \| DISEASES 63978 \| PRDM14 \| DISEASES 7013 \| TERF1 \| DISEASES 1030 \| CDKN2B \| DISEASES 3439 \| IFNA1 \| DISEASES 3934 \| LCN2 \| DISEASES 392399 \| LCN9 \| DISEASES 4851 \| NOTCH1 \| DISEASES 2620 \| GAS2 \| DISEASES 4863 \| NPAT \| DISEASES 472 \| ATM \| DISEASES 60496 \| AASDHPPT \| DISEASES 3145 \| HMBS \| DISEASES 90952 \| ESAM \| DISEASES 10398 \| MYL9 \| DISEASES 85449 \| KIAA1755 \| DISEASES 1848 \| DUSP6 \| DISEASES 51348 \| KLRF1 \| DISEASES 84159 \| ARID5B \| DISEASES 3176 \| HNMT \| DISEASES 27250 \| PDCD4 \| DISEASES 2823 \| GPM6A \| DISEASES 7424 \| VEGFC \| DISEASES 10666 \| CD226 \| DISEASES 3606 \| IL18 \| DISEASES 5805 \| PTS \| DISEASES 23457 \| ABCB9 \| DISEASES 4613 \| MYCN \| DISEASES 2241 \| FER \| DISEASES 5800 \| PTPRO \| DISEASES 2059 \| EPS8 \| DISEASES 79668 \| PARP8 \| DISEASES 55294 \| FBXW7 \| DISEASES 7292 \| TNFSF4 \| DISEASES 26040 \| SETBP1 \| DISEASES 115106 \| HAUS1 \| DISEASES 5741 \| PTH \| DISEASES 5140 \| PDE3B \| DISEASES 678 \| ZFP36L2 \| DISEASES 2321 \| FLT1 \| DISEASES 2697 \| GJA1 \| DISEASES 3087 \| HHEX \| DISEASES 3192 \| HNRNPU \| DISEASES 5903 \| RANBP2 \| DISEASES 10225 \| CD96 \| DISEASES 925 \| CD8A \| DISEASES 5205 \| ATP8B1 \| DISEASES 3206 \| HOXA10 \| DISEASES 1054 \| CEBPG \| DISEASES 124540 \| MSI2 \| DISEASES 7070 \| THY1 \| DISEASES 84959 \| UBASH3B \| DISEASES 2838 \| GPR15 \| DISEASES 7345 \| UCHL1 \| DISEASES 89780 \| WNT3A \| DISEASES 55760 \| DHX32 \| DISEASES 351 \| APP \| DISEASES 9510 \| ADAMTS1 \| DISEASES 8714 \| ABCC3 \| DISEASES 760 \| CA2 \| DISEASES 4956 \| ODF1 \| DISEASES 231 \| AKR1B1 \| DISEASES 843 \| CASP10 \| DISEASES 1436 \| CSF1R \| DISEASES 11197 \| WIF1 \| DISEASES 1633 \| DCK \| DISEASES 27163 \| NAAA \| DISEASES 9154 \| SLC28A1 \| DISEASES 10563 \| CXCL13 \| DISEASES 9246 \| UBE2L6 \| DISEASES 23522 \| KAT6B \| DISEASES 286053 \| NSMCE2 \| DISEASES 701 \| BUB1B \| DISEASES 6750 \| SST \| DISEASES 2177 \| FANCD2 \| DISEASES 5468 \| PPARG \| DISEASES 9069 \| CLDN12 \| DISEASES 3815 \| KIT \| DISEASES 7567 \| ZNF19 \| DISEASES 26060 \| APPL1 \| DISEASES 673 \| BRAF \| DISEASES 4690 \| NCK1 \| DISEASES 2176 \| FANCC \| DISEASES 5291 \| PIK3CB \| DISEASES 3017 \| HIST1H2BD \| DISEASES 8365 \| HIST1H4H \| DISEASES 909 \| CD1A \| DISEASES 57824 \| HMHB1 \| DISEASES 653361 \| NCF1 \| DISEASES 2207 \| FCER1G \| DISEASES 5909 \| RAP1GAP \| DISEASES 3460 \| IFNGR2 \| DISEASES 10642 \| IGF2BP1 \| DISEASES 27020 \| NPTN \| DISEASES 7832 \| BTG2 \| DISEASES 267 \| AMFR \| DISEASES 1487 \| CTBP1 \| DISEASES 115650 \| TNFRSF13C \| DISEASES 25865 \| PRKD2 \| DISEASES 808 \| CALM3 \| DISEASES 5316 \| PKNOX1 \| DISEASES 7307 \| U2AF1 \| DISEASES 89858 \| SIGLEC12 \| DISEASES 23547 \| LILRA4 \| DISEASES 115653 \| KIR3DL3 \| DISEASES 9437 \| NCR1 \| DISEASES 643 \| CXCR5 \| DISEASES 51043 \| ZBTB7B \| DISEASES 55585 \| UBE2Q1 \| DISEASES 729230 \| CCR2 \| DISEASES 1234 \| CCR5 \| DISEASES 84449 \| ZNF333 \| DISEASES 4056 \| LTC4S \| DISEASES 9794 \| MAML1 \| DISEASES 84911 \| ZNF382 \| DISEASES 114757 \| CYGB \| DISEASES 6352 \| CCL5 \| DISEASES 581 \| BAX \| DISEASES 6777 \| STAT5B \| DISEASES 3678 \| ITGA5 \| DISEASES 1973 \| EIF4A1 \| DISEASES 51517 \| NCKIPSD \| DISEASES 10482 \| NXF1 \| DISEASES 9965 \| FGF19 \| DISEASES 6886 \| TAL1 \| DISEASES 6006 \| RHCE \| DISEASES 2672 \| GFI1 \| DISEASES 7412 \| VCAM1 \| DISEASES 84838 \| ZNF496 \| DISEASES 2215 \| FCGR3B \| DISEASES 5966 \| REL \| DISEASES 51127 \| TRIM17 \| DISEASES 84661 \| DPY30 \| DISEASES 3754 \| KCNF1 \| DISEASES 2487 \| FRZB \| DISEASES 27306 \| HPGDS \| DISEASES 10461 \| MERTK \| DISEASES 56983 \| POGLUT1 \| DISEASES 6051 \| RNPEP \| DISEASES 3490 \| IGFBP7 \| DISEASES 3577 \| CXCR1 \| DISEASES 8320 \| EOMES \| DISEASES 57650 \| KIAA1524 \| DISEASES 50852 \| TRAT1 \| DISEASES 152185 \| SPICE1 \| DISEASES 213 \| ALB \| DISEASES 5473 \| PPBP \| DISEASES 5196 \| PF4 \| DISEASES 1230 \| CCR1 \| DISEASES 3693 \| ITGB5 \| DISEASES 6184 \| RPN1 \| DISEASES 22824 \| HSPA4L \| DISEASES 308 \| ANXA5 \| DISEASES 3600 \| IL15 \| DISEASES 3673 \| ITGA2 \| DISEASES 133619 \| PRRC1 \| DISEASES 9607 \| CARTPT \| DISEASES 3562 \| IL3 \| DISEASES 1437 \| CSF2 \| DISEASES 375519 \| GJB7 \| DISEASES 30012 \| TLX3 \| DISEASES 4869 \| NPM1 \| DISEASES 114801 \| TMEM200A \| DISEASES 819 \| CAMLG \| DISEASES 54882 \| ANKHD1 \| DISEASES 3313 \| HSPA9 \| DISEASES 6469 \| SHH \| DISEASES 5885 \| RAD21 \| DISEASES 4783 \| NFIL3 \| DISEASES 216 \| ALDH1A1 \| DISEASES 9833 \| MELK \| DISEASES 115825 \| WDFY2 \| DISEASES 2350 \| FOLR2 \| DISEASES 3636 \| INPPL1 \| DISEASES 3251 \| HPRT1 \| DISEASES 10206 \| TRIM13 \| DISEASES 9317 \| PTER \| DISEASES 161742 \| SPRED1 \| DISEASES 27343 \| POLL \| DISEASES 3611 \| ILK \| DISEASES 5896 \| RAG1 \| DISEASES 5055 \| SERPINB2 \| DISEASES 1381 \| CRABP1 \| DISEASES 201161 \| CENPV \| DISEASES 7184 \| HSP90B1 \| DISEASES 55718 \| POLR3E \| DISEASES 290 \| ANPEP \| DISEASES 5347 \| PLK1 \| DISEASES 6778 \| STAT6 \| DISEASES 58475 \| MS4A7 \| DISEASES 861 \| RUNX1 \| DISEASES 5245 \| PHB \| DISEASES 1398 \| CRK \| DISEASES 915 \| CD3D \| DISEASES 6240 \| RRM1 \| DISEASES 94235 \| GNG8 \| DISEASES 84669 \| USP32 \| DISEASES 558 \| AXL \| DISEASES 147945 \| NLRP4 \| DISEASES 84798 \| C19orf48 \| DISEASES 2125 \| EVPL \| DISEASES 332 \| BIRC5 \| DISEASES 7083 \| TK1 \| DISEASES 21 \| ABCA3 \| DISEASES 8772 \| FADD \| DISEASES 55872 \| PBK \| DISEASES 84132 \| USP42 \| DISEASES 3960 \| LGALS4 \| DISEASES 4255 \| MGMT \| DISEASES 4807 \| NHLH1 \| DISEASES 133418 \| EMB \| DISEASES 9081 \| PRY \| DISEASES 5604 \| MAP2K1 \| DISEASES 699 \| BUB1 \| DISEASES 51523 \| CXXC5 \| DISEASES 598 \| BCL2L1 \| DISEASES 7343 \| UBTF \| DISEASES 3479 \| IGF1 \| DISEASES 2990 \| GUSB \| DISEASES 23214 \| XPO6 \| DISEASES 6795 \| AURKC \| DISEASES 3603 \| IL16 \| DISEASES 3308 \| HSPA4 \| DISEASES 8841 \| HDAC3 \| DISEASES 8233 \| ZRSR2 \| DISEASES 3689 \| ITGB2 \| DISEASES 6036 \| RNASE2 \| DISEASES 442862 \| PRY2 \| DISEASES 3726 \| JUNB \| DISEASES 3688 \| ITGB1 \| DISEASES 3012 \| HIST1H2AE \| DISEASES 8988 \| HSPB3 \| DISEASES 613 \| BCR \| DISEASES 993 \| CDC25A \| DISEASES 442866 \| PRYP4 \| DISEASES 1493 \| CTLA4 \| DISEASES 2815 \| GP9 \| DISEASES 10114 \| HIPK3 \| DISEASES 929 \| CD14 \| DISEASES 171558 \| PTCRA \| DISEASES 1495 \| CTNNA1 \| DISEASES 341152 \| OR2AT4 \| DISEASES 3596 \| IL13 \| DISEASES 4330 \| MN1 \| DISEASES 7543 \| ZFX \| DISEASES 1602 \| DACH1 \| DISEASES 5579 \| PRKCB \| DISEASES 1901 \| S1PR1 \| DISEASES 1051 \| CEBPB \| DISEASES 2237 \| FEN1 \| DISEASES 3627 \| CXCL10 \| DISEASES 25998 \| IBTK \| DISEASES 8019 \| BRD3 \| DISEASES 6579 \| SLCO1A2 \| DISEASES 3575 \| IL7R \| DISEASES 6504 \| SLAMF1 \| DISEASES 2353 \| FOS \| DISEASES 3708 \| ITPR1 \| DISEASES 4968 \| OGG1 \| DISEASES 3669 \| ISG20 \| DISEASES 8493 \| PPM1D \| DISEASES 9079 \| LDB2 \| DISEASES 57099 \| AVEN \| DISEASES 150353 \| DNAJB7 \| DISEASES 9836 \| LCMT2 \| DISEASES 9451 \| EIF2AK3 \| DISEASES 57521 \| RPTOR \| DISEASES 54541 \| DDIT4 \| DISEASES 8028 \| MLLT10 \| DISEASES 54205 \| CYCS \| DISEASES 27087 \| B3GAT1 \| DISEASES 1938 \| EEF2 \| DISEASES 10855 \| HPSE \| DISEASES 695 \| BTK \| DISEASES 3213 \| HOXB3 \| DISEASES 197259 \| MLKL \| DISEASES 4046 \| LSP1 \| DISEASES 6199 \| RPS6KB2 \| DISEASES 991 \| CDC20 \| DISEASES 2147 \| F2 \| DISEASES 5897 \| RAG2 \| DISEASES 6363 \| CCL19 \| DISEASES 6573 \| SLC19A1 \| DISEASES 1540 \| CYLD \| DISEASES 5340 \| PLG \| DISEASES 572 \| BAD \| DISEASES 5778 \| PTPN7 \| DISEASES 79370 \| BCL2L14 \| DISEASES 84285 \| EIF1AD \| DISEASES 9134 \| CCNE2 \| DISEASES 3219 \| HOXB9 \| DISEASES 7534 \| YWHAZ \| DISEASES 3054 \| HCFC1 \| DISEASES 7015 \| TERT \| DISEASES 1072 \| CFL1 \| DISEASES 4023 \| LPL \| DISEASES 3265 \| HRAS \| DISEASES 947 \| CD34 \| DISEASES 3661 \| IRF3 \| DISEASES 56675 \| NRIP3 \| DISEASES 3310 \| HSPA6 \| DISEASES 10125 \| RASGRP1 \| DISEASES 8793 \| TNFRSF10D \| DISEASES 8815 \| BANF1 \| DISEASES 9610 \| RIN1 \| DISEASES 27115 \| PDE7B \| DISEASES 5598 \| MAPK7 \| DISEASES 6208 \| RPS14 \| DISEASES 836 \| CASP3 \| DISEASES 131450 \| CD200R1 \| DISEASES 29990 \| PILRB \| DISEASES 64393 \| ZMAT3 \| DISEASES 2000 \| ELF4 \| DISEASES 2944 \| GSTM1 \| DISEASES 5771 \| PTPN2 \| DISEASES 10007 \| GNPDA1 \| DISEASES 84868 \| HAVCR2 \| DISEASES 924 \| CD7 \| DISEASES 10221 \| TRIB1 \| DISEASES 5319 \| PLA2G1B \| DISEASES 7172 \| TPMT \| DISEASES 8832 \| CD84 \| DISEASES 4778 \| NFE2 \| DISEASES 8837 \| CFLAR \| DISEASES 79870 \| BAALC \| DISEASES 3952 \| LEP \| DISEASES 835 \| CASP2 \| DISEASES 3172 \| HNF4A \| DISEASES 4793 \| NFKBIB \| DISEASES 5591 \| PRKDC \| DISEASES 653499 \| LGALS7B \| DISEASES 80818 \| ZNF436 \| DISEASES 8877 \| SPHK1 \| DISEASES 92745 \| SLC38A5 \| DISEASES 80169 \| CTC1 \| DISEASES 10868 \| USP20 \| DISEASES 23047 \| PDS5B \| DISEASES 4179 \| CD46 \| DISEASES 3090 \| HIC1 \| DISEASES 354 \| KLK3 \| DISEASES 10009 \| ZBTB33 \| DISEASES 1662 \| DDX10 \| DISEASES 9448 \| MAP4K4 \| DISEASES 998 \| CDC42 \| DISEASES 51593 \| SRRT \| DISEASES 2629 \| GBA \| DISEASES 931 \| MS4A1 \| DISEASES 1831 \| TSC22D3 \| DISEASES 285 \| ANGPT2 \| DISEASES 27122 \| DKK3 \| DISEASES 6047 \| RNF4 \| DISEASES 25758 \| KIAA1549L \| DISEASES 7298 \| TYMS \| DISEASES 901 \| CCNG2 \| DISEASES 3936 \| LCP1 \| DISEASES 6773 \| STAT2 \| DISEASES 10859 \| LILRB1 \| DISEASES 4928 \| NUP98 \| DISEASES 7334 \| UBE2N \| DISEASES 4261 \| CIITA \| DISEASES 1604 \| CD55 \| DISEASES 8239 \| USP9X \| DISEASES 4302 \| MLLT6 \| DISEASES 8560 \| DEGS1 \| DISEASES 23512 \| SUZ12 \| DISEASES 57381 \| RHOJ \| DISEASES 5551 \| PRF1 \| DISEASES 3291 \| HSD11B2 \| DISEASES 2824 \| GPM6B \| DISEASES 51301 \| GCNT4 \| DISEASES 4233 \| MET \| DISEASES 2529 \| FUT7 \| DISEASES 4691 \| NCL \| DISEASES 4684 \| NCAM1 \| DISEASES 637 \| BID \| DISEASES 6470 \| SHMT1 \| DISEASES 23786 \| BCL2L13 \| DISEASES 27086 \| FOXP1 \| DISEASES 5912 \| RAP2B \| DISEASES 10419 \| PRMT5 \| DISEASES 10892 \| MALT1 \| DISEASES 3579 \| CXCR2 \| DISEASES 10726 \| NUDC \| DISEASES 1728 \| NQO1 \| DISEASES 80381 \| CD276 \| DISEASES 2146 \| EZH2 \| DISEASES 3059 \| HCLS1 \| DISEASES 80237 \| ELL3 \| DISEASES 7367 \| UGT2B17 \| DISEASES 1827 \| RCAN1 \| DISEASES 811 \| CALR \| DISEASES 27181 \| SIGLEC8 \| DISEASES 6863 \| TAC1 \| DISEASES 10782 \| ZNF274 \| DISEASES 8334 \| HIST1H2AC \| DISEASES 9920 \| KBTBD11 \| DISEASES 3615 \| IMPDH2 \| DISEASES 995 \| CDC25C \| DISEASES 10611 \| PDLIM5 \| DISEASES 5345 \| SERPINF2 \| DISEASES 205 \| AK4 \| DISEASES 3039 \| HBA1 \| DISEASES 6478 \| SIAH2 \| DISEASES 6664 \| SOX11 \| DISEASES 79142 \| PHF23 \| DISEASES 284427 \| SLC25A41 \| DISEASES 9203 \| ZMYM3 \| DISEASES 1879 \| EBF1 \| DISEASES 2274 \| FHL2 \| DISEASES 9202 \| ZMYM4 \| DISEASES 23635 \| SSBP2 \| DISEASES 55 \| ACPP \| DISEASES 5932 \| RBBP8 \| DISEASES 90480 \| GADD45GIP1 \| DISEASES 8844 \| KSR1 \| DISEASES 923 \| CD6 \| DISEASES 8243 \| SMC1A \| DISEASES 6657 \| SOX2 \| DISEASES 3309 \| HSPA5 \| DISEASES 283518 \| KCNRG \| DISEASES 84260 \| TCHP \| DISEASES 7791 \| ZYX \| DISEASES 8408 \| ULK1 \| DISEASES 2314 \| FLII \| DISEASES 1555 \| CYP2B6 \| DISEASES 7525 \| YES1 \| DISEASES 9235 \| IL32 \| DISEASES 2932 \| GSK3B \| DISEASES 8227 \| AKAP17A \| DISEASES 7329 \| UBE2I \| DISEASES 154141 \| MBOAT1 \| DISEASES 148266 \| ZNF569 \| DISEASES 5241 \| PGR \| DISEASES 1176 \| AP3S1 \| DISEASES 5324 \| PLAG1 \| DISEASES 951 \| CD37 \| DISEASES 56984 \| PSMG2 \| DISEASES 5366 \| PMAIP1 \| DISEASES 23185 \| LARP4B \| DISEASES 219285 \| SAMD9L \| DISEASES 1974 \| EIF4A2 \| DISEASES 79447 \| PAGR1 \| DISEASES 51780 \| KDM3B \| DISEASES 3052 \| HCCS \| DISEASES 161882 \| ZFPM1 \| DISEASES 6097 \| RORC \| DISEASES 4094 \| MAF \| DISEASES 8204 \| NRIP1 \| DISEASES 1435 \| CSF1 \| DISEASES 8548 \| BLZF1 \| DISEASES 5902 \| RANBP1 \| DISEASES 1482 \| NKX2-5 \| DISEASES 5034 \| P4HB \| DISEASES 4772 \| NFATC1 \| DISEASES 3563 \| IL3RA \| DISEASES 3714 \| JAG2 \| DISEASES 9241 \| NOG \| DISEASES 8784 \| TNFRSF18 \| DISEASES 1789 \| DNMT3B \| DISEASES 10614 \| HEXIM1 \| DISEASES 29933 \| GPR132 \| DISEASES 3214 \| HOXB4 \| DISEASES 7404 \| UTY \| DISEASES 706 \| TSPO \| DISEASES 10456 \| HAX1 \| DISEASES 84295 \| PHF6 \| DISEASES 752 \| FMNL1 \| DISEASES 3543 \| IGLL1 \| DISEASES 6667 \| SP1 \| DISEASES 2811 \| GP1BA \| DISEASES 3665 \| IRF7 \| DISEASES 8651 \| SOCS1 \| DISEASES 1850 \| DUSP8 \| DISEASES 596 \| BCL2 \| DISEASES 29110 \| TBK1 \| DISEASES 3009 \| HIST1H1B \| DISEASES 842 \| CASP9 \| DISEASES 9021 \| SOCS3 \| DISEASES 6612 \| SUMO3 \| DISEASES 5155 \| PDGFB \| DISEASES 3953 \| LEPR \| DISEASES 79680 \| C22orf29 \| DISEASES 6900 \| CNTN2 \| DISEASES 2188 \| FANCF \| DISEASES 6938 \| TCF12 \| DISEASES 926 \| CD8B \| DISEASES 9146 \| HGS \| DISEASES 7490 \| WT1 \| DISEASES 2242 \| FES \| DISEASES 71 \| ACTG1 \| DISEASES 10320 \| IKZF1 \| DISEASES 144608 \| C12orf60 \| DISEASES 6401 \| SELE \| DISEASES 3212 \| HOXB2 \| DISEASES 796 \| CALCA \| DISEASES 2621 \| GAS6 \| DISEASES 6007 \| RHD \| DISEASES 3418 \| IDH2 \| DISEASES 942 \| CD86 \| DISEASES 9988 \| DMTF1 \| DISEASES 8338 \| HIST2H2AC \| DISEASES 11156 \| PTP4A3 \| DISEASES 5915 \| RARB \| DISEASES 5727 \| PTCH1 \| DISEASES 1485 \| CTAG1B \| DISEASES 1233 \| CCR4 \| DISEASES 5813 \| PURA \| DISEASES 25901 \| CCDC28A \| DISEASES 2185 \| PTK2B \| DISEASES 4088 \| SMAD3 \| DISEASES 8013 \| NR4A3 \| DISEASES 7318 \| UBA7 \| DISEASES 3916 \| LAMP1 \| DISEASES 4600 \| MX2 \| DISEASES 6472 \| SHMT2 \| DISEASES 682 \| BSG \| DISEASES 2124 \| EVI2B \| DISEASES 151888 \| BTLA \| DISEASES 10057 \| ABCC5 \| DISEASES 3043 \| HBB \| DISEASES 10013 \| HDAC6 \| DISEASES 2152 \| F3 \| DISEASES 55693 \| KDM4D \| DISEASES 2009 \| EML1 \| DISEASES 57178 \| ZMIZ1 \| DISEASES 6887 \| TAL2 \| DISEASES 54997 \| TESC \| DISEASES 55589 \| BMP2K \| DISEASES 5133 \| PDCD1 \| DISEASES 5501 \| PPP1CC \| DISEASES 3320 \| HSP90AA1 \| DISEASES 23451 \| SF3B1 \| DISEASES 8856 \| NR1I2 \| DISEASES 11335 \| CBX3 \| DISEASES 5889 \| RAD51C \| DISEASES 8653 \| DDX3Y \| DISEASES 81608 \| FIP1L1 \| DISEASES 283 \| ANG \| DISEASES 3802 \| KIR2DL1 \| DISEASES 468 \| ATF4 \| DISEASES 1032 \| CDKN2D \| DISEASES 4221 \| MEN1 \| DISEASES 91663 \| MYADM \| DISEASES 9138 \| ARHGEF1 \| DISEASES 7767 \| ZNF224 \| DISEASES 677 \| ZFP36L1 \| DISEASES 51339 \| DACT1 \| DISEASES 84324 \| SARNP \| DISEASES 5529 \| PPP2R5E \| DISEASES 154661 \| RUNDC3B \| DISEASES 4835 \| NQO2 \| DISEASES 200162 \| SPAG17 \| DISEASES 3932 \| LCK \| DISEASES 7189 \| TRAF6 \| DISEASES 1576 \| CYP3A4 \| DISEASES 3091 \| HIF1A \| DISEASES 1981 \| EIF4G1 \| DISEASES 554 \| AVPR2 \| DISEASES 3824 \| KLRD1 \| DISEASES 7704 \| ZBTB16 \| DISEASES 2289 \| FKBP5 \| DISEASES 23236 \| PLCB1 \| DISEASES 4004 \| LMO1 \| DISEASES 92140 \| MTDH \| DISEASES 6622 \| SNCA \| DISEASES 5269 \| SERPINB6 \| DISEASES 2246 \| FGF1 \| DISEASES 23583 \| SMUG1 \| DISEASES 55617 \| TASP1 \| DISEASES 53335 \| BCL11A \| DISEASES 3572 \| IL6ST \| DISEASES 203068 \| TUBB \| DISEASES 2885 \| GRB2 \| DISEASES 57496 \| MKL2 \| DISEASES 3266 \| ERAS \| DISEASES 9402 \| GRAP2 \| DISEASES 857 \| CAV1 \| DISEASES 5329 \| PLAUR \| DISEASES 1235 \| CCR6 \| DISEASES 8835 \| SOCS2 \| DISEASES 22978 \| NT5C2 \| DISEASES 2309 \| FOXO3 \| DISEASES 3006 \| HIST1H1C \| DISEASES 3805 \| KIR2DL4 \| DISEASES 85480 \| TSLP \| DISEASES 2261 \| FGFR3 \| DISEASES 29102 \| DROSHA \| DISEASES 4602 \| MYB \| DISEASES 9516 \| LITAF \| DISEASES 966 \| CD59 \| DISEASES 57826 \| RAP2C \| DISEASES 1982 \| EIF4G2 \| DISEASES 8788 \| DLK1 \| DISEASES 10524 \| KAT5 \| DISEASES 6932 \| TCF7 \| DISEASES 5910 \| RAP1GDS1 \| DISEASES 6575 \| SLC20A2 \| DISEASES 8805 \| TRIM24 \| DISEASES 5493 \| PPL \| DISEASES 1978 \| EIF4EBP1 \| DISEASES 4208 \| MEF2C \| DISEASES 9070 \| ASH2L \| DISEASES 5781 \| PTPN11 \| DISEASES 2810 \| SFN \| DISEASES 1447 \| CSN2 \| DISEASES 5747 \| PTK2 \| DISEASES 6776 \| STAT5A \| DISEASES 8717 \| TRADD \| DISEASES 3720 \| JARID2 \| DISEASES 22837 \| COBLL1 \| DISEASES 4089 \| SMAD4 \| DISEASES 374383 \| NCR3LG1 \| DISEASES 653145 \| ANXA8 \| DISEASES 3178 \| HNRNPA1 \| DISEASES 51513 \| ETV7 \| DISEASES 27255 \| CNTN6 \| DISEASES 1508 \| CTSB \| DISEASES 2272 \| FHIT \| DISEASES 6049 \| RNF6 \| DISEASES 259197 \| NCR3 \| DISEASES 6731 \| SRP72 \| DISEASES 3804 \| KIR2DL3 \| DISEASES 2305 \| FOXM1 \| DISEASES 442865 \| PRYP3 \| DISEASES 921 \| CD5 \| DISEASES 159296 \| NKX2-3 \| DISEASES 6672 \| SP100 \| DISEASES 3146 \| HMGB1 \| DISEASES 54496 \| PRMT7 \| DISEASES 3716 \| JAK1 \| DISEASES 9623 \| TCL1B \| DISEASES 8360 \| HIST1H4D \| DISEASES 9474 \| ATG5 \| DISEASES 284415 \| VSTM1 \| DISEASES 7517 \| XRCC3 \| DISEASES 9577 \| BRE \| DISEASES 864 \| RUNX3 \| DISEASES 7874 \| USP7 \| DISEASES 3205 \| HOXA9 \| DISEASES 3344 \| FOXN2 \| DISEASES 545 \| ATR \| DISEASES 23405 \| DICER1 \| DISEASES 26053 \| AUTS2 \| DISEASES 1003 \| CDH5 \| DISEASES 20 \| ABCA2 \| DISEASES 3605 \| IL17A \| DISEASES 94241 \| TP53INP1 \| DISEASES 10234 \| LRRC17 \| DISEASES 53827 \| FXYD5 \| DISEASES 389421 \| LIN28B \| DISEASES 1499 \| CTNNB1 \| DISEASES 875 \| CBS \| DISEASES 3005 \| H1F0 \| DISEASES 22806 \| IKZF3 \| DISEASES 900 \| CCNG1 \| DISEASES 8328 \| GFI1B \| DISEASES 8073 \| PTP4A2 \| DISEASES 9232 \| PTTG1 \| DISEASES 81848 \| SPRY4 \| DISEASES 5606 \| MAP2K3 \| DISEASES 3614 \| IMPDH1 \| DISEASES 3516 \| RBPJ \| DISEASES 159195 \| USP54 \| DISEASES 6483 \| ST3GAL2 \| DISEASES 10019 \| SH2B3 \| DISEASES 5359 \| PLSCR1 \| DISEASES 9218 \| VAPA \| DISEASES 2624 \| GATA2 \| DISEASES 3767 \| KCNJ11 \| DISEASES 538 \| ATP7A \| DISEASES 8326 \| FZD9 \| DISEASES 1811 \| SLC26A3 \| DISEASES 6227 \| RPS21 \| DISEASES 302 \| ANXA2 \| DISEASES 3921 \| RPSA \| DISEASES 6146 \| RPL22 \| DISEASES 2879 \| GPX4 \| DISEASES 1399 \| CRKL \| DISEASES 8294 \| HIST1H4I \| DISEASES 4205 \| MEF2A \| DISEASES 6050 \| RNH1 \| DISEASES 10533 \| ATG7 \| DISEASES 6925 \| TCF4 \| DISEASES 79711 \| IPO4 \| DISEASES 309 \| ANXA6 \| DISEASES 2534 \| FYN \| DISEASES 90427 \| BMF \| DISEASES 79971 \| WLS \| DISEASES 2335 \| FN1 \| DISEASES 2331 \| FMOD \| DISEASES 8363 \| HIST1H4J \| DISEASES 8650 \| NUMB \| DISEASES 728 \| C5AR1 \| DISEASES 641 \| BLM \| DISEASES 23111 \| SPG20 \| DISEASES 221477 \| C6orf89 \| DISEASES 84936 \| ZFYVE19 \| DISEASES 5926 \| ARID4A \| DISEASES 80781 \| COL18A1 \| DISEASES 148741 \| ANKRD35 \| DISEASES 57591 \| MKL1 \| DISEASES 331 \| XIAP \| DISEASES 1785 \| DNM2 \| DISEASES 160364 \| CLEC12A \| DISEASES 5979 \| RET \| DISEASES 8764 \| TNFRSF14 \| DISEASES 355 \| FAS \| DISEASES 5265 \| SERPINA1 \| DISEASES 9260 \| PDLIM7 \| DISEASES 3240 \| HP \| DISEASES 8368 \| HIST1H4L \| DISEASES 140885 \| SIRPA \| DISEASES 51710 \| ZNF44 \| DISEASES 5905 \| RANGAP1 \| DISEASES 10425 \| ARIH2 \| DISEASES 5906 \| RAP1A \| DISEASES 3899 \| AFF3 \| DISEASES 10507 \| SEMA4D \| DISEASES 6288 \| SAA1 \| DISEASES 8344 \| HIST1H2BE \| DISEASES 1822 \| ATN1 \| DISEASES 4100 \| MAGEA1 \| DISEASES 6477 \| SIAH1 \| DISEASES 3683 \| ITGAL \| DISEASES 29116 \| MYLIP \| DISEASES 2803 \| GOLGA4 \| DISEASES 8794 \| TNFRSF10C \| DISEASES 801 \| CALM1 \| DISEASES 1635 \| DCTD \| DISEASES 5625 \| PRODH \| DISEASES 987 \| LRBA \| DISEASES 64919 \| BCL11B \| DISEASES 79930 \| DOK3 \| DISEASES 6421 \| SFPQ \| DISEASES 253260 \| RICTOR \| DISEASES 60 \| ACTB \| DISEASES 9961 \| MVP \| DISEASES 3177 \| SLC29A2 \| DISEASES 728378 \| POTEF \| DISEASES 8362 \| HIST1H4K \| DISEASES 10803 \| CCR9 \| DISEASES 5169 \| ENPP3 \| DISEASES 4097 \| MAFG \| DISEASES 26151 \| NAT9 \| DISEASES 6597 \| SMARCA4 \| DISEASES 121504 \| HIST4H4 \| DISEASES 1612 \| DAPK1 \| DISEASES 5079 \| PAX5 \| DISEASES 871 \| SERPINH1 \| DISEASES 2050 \| EPHB4 \| DISEASES 6714 \| SRC \| DISEASES 4763 \| NF1 \| DISEASES 285527 \| FRYL \| DISEASES 51592 \| TRIM33 \| DISEASES 841 \| CASP8 \| DISEASES 5893 \| RAD52 \| DISEASES 5699 \| PSMB10 \| DISEASES 405 \| ARNT \| DISEASES 11091 \| WDR5 \| DISEASES 2213 \| FCGR2B \| DISEASES 2526 \| FUT4 \| DISEASES 56980 \| PRDM10 \| DISEASES 4217 \| MAP3K5 \| DISEASES 3821 \| KLRC1 \| DISEASES 9332 \| CD163 \| DISEASES 728113 \| ANXA8L1 \| DISEASES 5294 \| PIK3CG \| DISEASES 11086 \| ADAM29 \| DISEASES 2547 \| XRCC6 \| DISEASES 5336 \| PLCG2 \| DISEASES 8021 \| NUP214 \| DISEASES 8822 \| FGF17 \| DISEASES 5094 \| PCBP2 \| DISEASES 1786 \| DNMT1 \| DISEASES 2013 \| EMP2 \| DISEASES 3635 \| INPP5D \| DISEASES 154214 \| RNF217 \| DISEASES 4192 \| MDK \| DISEASES 8359 \| HIST1H4A \| DISEASES 6427 \| SRSF2 \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 79947 \| DHDDS \| DISEASES 3201 \| HOXA4 \| DISEASES 7037 \| TFRC \| DISEASES 6693 \| SPN \| DISEASES 2114 \| ETS2 \| DISEASES 2157 \| F8 \| DISEASES 1523 \| CUX1 \| DISEASES 3164 \| NR4A1 \| DISEASES 4638 \| MYLK \| DISEASES 3135 \| HLA-G \| DISEASES 5599 \| MAPK8 \| DISEASES 170482 \| CLEC4C \| DISEASES 25942 \| SIN3A \| DISEASES 8367 \| HIST1H4E \| DISEASES 4311 \| MME \| DISEASES 1803 \| DPP4 \| DISEASES 10210 \| TOPORS \| DISEASES 6241 \| RRM2 \| DISEASES 1565 \| CYP2D6 \| DISEASES 415116 \| PIM3 \| DISEASES 9361 \| LONP1 \| DISEASES 54106 \| TLR9 \| DISEASES 578 \| BAK1 \| DISEASES 2993 \| GYPA \| DISEASES 23560 \| GTPBP4 \| DISEASES 4916 \| NTRK3 \| DISEASES 10848 \| PPP1R13L \| DISEASES 219972 \| MPEG1 \| DISEASES 6772 \| STAT1 \| DISEASES 7150 \| TOP1 \| DISEASES 4860 \| PNP \| DISEASES 2475 \| MTOR \| DISEASES 916 \| CD3E \| DISEASES 2736 \| GLI2 \| DISEASES 171017 \| ZNF384 \| DISEASES 51438 \| MAGEC2 \| DISEASES 83416 \| FCRL5 \| DISEASES 11214 \| AKAP13 \| DISEASES 9126 \| SMC3 \| DISEASES 57213 \| SPRYD7 \| DISEASES 919 \| CD247 \| DISEASES 54739 \| XAF1 \| DISEASES 259230 \| SGMS1 \| DISEASES 9760 \| TOX \| DISEASES 10724 \| MGEA5 \| DISEASES 4283 \| CXCL9 \| DISEASES 7096 \| TLR1 \| DISEASES 9846 \| GAB2 \| DISEASES 8863 \| PER3 \| DISEASES 4515 \| MTCP1 \| DISEASES 10580 \| SORBS1 \| DISEASES 79368 \| FCRL2 \| DISEASES 8678 \| BECN1 \| DISEASES 5891 \| MOK \| DISEASES 23038 \| WDTC1 \| DISEASES 5693 \| PSMB5 \| DISEASES 961 \| CD47 \| DISEASES 4548 \| MTR \| DISEASES 359948 \| IRF2BP2 \| DISEASES 28514 \| DLL1 \| DISEASES 142 \| PARP1 \| DISEASES 83881 \| MIXL1 \| DISEASES 11116 \| FGFR1OP \| DISEASES 3142 \| HLX \| DISEASES 56950 \| SMYD2 \| DISEASES 6580 \| SLC22A1 \| DISEASES 3664 \| IRF6 \| DISEASES 50486 \| G0S2 \| DISEASES 1378 \| CR1 \| DISEASES 1380 \| CR2 \| DISEASES 5208 \| PFKFB2 \| DISEASES 6993 \| DYNLT1 \| DISEASES 9261 \| MAPKAPK2 \| DISEASES 4194 \| MDM4 \| DISEASES 79465 \| ULBP3 \| DISEASES 80328 \| ULBP2 \| DISEASES 5788 \| PTPRC \| DISEASES 51377 \| UCHL5 \| DISEASES 5996 \| RGS1 \| DISEASES 5321 \| PLA2G4A \| DISEASES 5743 \| PTGS2 \| DISEASES 54823 \| SWT1 \| DISEASES 6045 \| RNF2 \| DISEASES 6041 \| RNASEL \| DISEASES 9213 \| XPR1 \| DISEASES 462 \| SERPINC1 \| DISEASES 356 \| FASLG \| DISEASES 3459 \| IFNGR1 \| DISEASES 55811 \| ADCY10 \| DISEASES 92241 \| RCSD1 \| DISEASES 22926 \| ATF6 \| DISEASES 84824 \| FCRLA \| DISEASES 2214 \| FCGR3A \| DISEASES 6391 \| SDHC \| DISEASES 51744 \| CD244 \| DISEASES 4063 \| LY9 \| DISEASES 57823 \| SLAMF7 \| DISEASES 962 \| CD48 \| DISEASES 114836 \| SLAMF6 \| DISEASES 343413 \| FCRL6 \| DISEASES 3428 \| IFI16 \| DISEASES 4332 \| MNDA \| DISEASES 911 \| CD1C \| DISEASES 912 \| CD1D \| DISEASES 115350 \| FCRL1 \| DISEASES 9826 \| ARHGEF11 \| DISEASES 632 \| BGLAP \| DISEASES 6016 \| RIT1 \| DISEASES 4580 \| MTX1 \| DISEASES 4582 \| MUC1 \| DISEASES 57326 \| PBXIP1 \| DISEASES 103 \| ADAR \| DISEASES 3570 \| IL6R \| DISEASES 27287 \| VENTX \| DISEASES 4082 \| MARCKS \| DISEASES 664 \| BNIP3 \| DISEASES 4288 \| MKI67 \| DISEASES 6280 \| S100A9 \| DISEASES 4014 \| LOR \| DISEASES 7062 \| TCHH \| DISEASES 6281 \| S100A10 \| DISEASES 4942 \| OAT \| DISEASES 262 \| AMD1 \| DISEASES 10962 \| MLLT11 \| DISEASES 4170 \| MCL1 \| DISEASES 55278 \| QRSL1 \| DISEASES 9531 \| BAG3 \| DISEASES 639 \| PRDM1 \| DISEASES 8661 \| EIF3A \| DISEASES 8349 \| HIST2H2BE \| DISEASES 554313 \| HIST2H4B \| DISEASES 8337 \| HIST2H2AA3 \| DISEASES 8370 \| HIST2H4A \| DISEASES 2209 \| FCGR1A \| DISEASES 5406 \| PNLIP \| DISEASES 10628 \| TXNIP \| DISEASES 840 \| CASP7 \| DISEASES 26227 \| PHGDH \| DISEASES 914 \| CD2 \| DISEASES 965 \| CD58 \| DISEASES 4803 \| NGF \| DISEASES 4893 \| NRAS \| DISEASES 1847 \| DUSP5 \| DISEASES 8517 \| IKBKG \| DISEASES 9892 \| SNAP91 \| DISEASES 140 \| ADORA3 \| DISEASES 3738 \| KCNA3 \| DISEASES 64783 \| RBM15 \| DISEASES 22984 \| PDCD11 \| DISEASES 84108 \| PCGF6 \| DISEASES 4791 \| NFKB2 \| DISEASES 8945 \| BTRC \| DISEASES 10660 \| LBX1 \| DISEASES 3195 \| TLX1 \| DISEASES 55510 \| DDX43 \| DISEASES 3149 \| HMGB3 \| DISEASES 1147 \| CHUK \| DISEASES 1244 \| ABCC2 \| DISEASES 2334 \| AFF2 \| DISEASES 2959 \| GTF2B \| DISEASES 1038 \| CDR1 \| DISEASES 2258 \| FGF13 \| DISEASES 959 \| CD40LG \| DISEASES 728911 \| CT45A2 \| DISEASES 54810 \| GIPC2 \| DISEASES 5688 \| PSMA7 \| DISEASES 55970 \| GNG12 \| DISEASES 1647 \| GADD45A \| DISEASES 26135 \| SERBP1 \| DISEASES 23401 \| FRAT2 \| DISEASES 4919 \| ROR1 \| DISEASES 5236 \| PGM1 \| DISEASES 4068 \| SH2D1A \| DISEASES 1791 \| DNTT \| DISEASES 4774 \| NFIA \| DISEASES 953 \| ENTPD1 \| DISEASES 3725 \| JUN \| DISEASES 84528 \| RHOXF2 \| DISEASES 860 \| RUNX2 \| DISEASES 3755 \| KCNG1 \| DISEASES 8813 \| DPM1 \| DISEASES 5770 \| PTPN1 \| DISEASES 2030 \| SLC29A1 \| DISEASES 2060 \| EPS15 \| DISEASES 3437 \| IFIT3 \| DISEASES 7410 \| VAV2 \| DISEASES 6491 \| STIL \| DISEASES 8569 \| MKNK1 \| DISEASES 5728 \| PTEN \| DISEASES 5900 \| RALGDS \| DISEASES 7422 \| VEGFA \| DISEASES 2889 \| RAPGEF1 \| DISEASES 958 \| CD40 \| DISEASES 4318 \| MMP9 \| DISEASES 25 \| ABL1 \| DISEASES 9682 \| KDM4A \| DISEASES 4352 \| MPL \| DISEASES 5476 \| CTSA \| DISEASES 1503 \| CTPS1 \| DISEASES 2021 \| ENDOG \| DISEASES 6418 \| SET \| DISEASES 55859 \| BEX1 \| DISEASES 5328 \| PLAU \| DISEASES 10450 \| PPIE \| DISEASES 100 \| ADA \| DISEASES 1759 \| DNM1 \| DISEASES 896 \| CCND3 \| DISEASES 3633 \| INPP5B \| DISEASES 9436 \| NCR2 \| DISEASES 1441 \| CSF3R \| DISEASES 11122 \| PTPRT \| DISEASES 2022 \| ENG \| DISEASES 1979 \| EIF4EBP2 \| DISEASES 2356 \| FPGS \| DISEASES 1025 \| CDK9 \| DISEASES 9935 \| MAFB \| DISEASES 546 \| ATRX \| DISEASES 8565 \| YARS \| DISEASES 5090 \| PBX3 \| DISEASES 5928 \| RBBP4 \| DISEASES 5292 \| PIM1 \| DISEASES 1046 \| CDX4 \| DISEASES 65108 \| MARCKSL1 \| DISEASES 3065 \| HDAC1 \| DISEASES 55869 \| HDAC8 \| DISEASES 9355 \| LHX2 \| DISEASES 80312 \| TET1 \| DISEASES 2833 \| CXCR3 \| DISEASES 2934 \| GSN \| DISEASES 7185 \| TRAF1 \| DISEASES 22943 \| DKK1 \| DISEASES 7099 \| TLR4 \| DISEASES 2268 \| FGR \| DISEASES 9966 \| TNFSF15 \| DISEASES 3561 \| IL2RG \| DISEASES 1043 \| CD52 \| DISEASES 4303 \| FOXO4 \| DISEASES 7357 \| UGCG \| DISEASES 3710 \| ITPR3 \| DISEASES 240 \| ALOX5 \| DISEASES 3692 \| EIF6 \| DISEASES 1269 \| CNR2 \| DISEASES 7295 \| TXN \| DISEASES 3399 \| ID3 \| DISEASES 9314 \| KLF4 \| DISEASES 367 \| AR \| DISEASES 316 \| AOX1 \| DISEASES 5698 \| PSMB9 \| DISEASES 54534 \| MRPL50 \| DISEASES 4855 \| NOTCH4 \| DISEASES 5089 \| PBX2 \| DISEASES 978 \| CDA \| DISEASES 3014 \| H2AFX \| DISEASES 10919 \| EHMT2 \| DISEASES 2155 \| F7 \| DISEASES 3303 \| HSPA1A \| DISEASES 171023 \| ASXL1 \| DISEASES 6850 \| SYK \| DISEASES 3055 \| HCK \| DISEASES 10673 \| TNFSF13B \| DISEASES 79670 \| ZCCHC6 \| DISEASES 7917 \| BAG6 \| DISEASES 22852 \| ANKRD26 \| DISEASES 3397 \| ID1 \| DISEASES 10006 \| ABI1 \| DISEASES 50943 \| FOXP3 \| DISEASES 100507436 \| MICA \| DISEASES 3107 \| HLA-C \| DISEASES 64078 \| SLC28A3 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 3190 \| HNRNPK \| DISEASES 84267 \| C9orf64 \| DISEASES 9656 \| MDC1 \| DISEASES 158158 \| RASEF \| DISEASES 7088 \| TLE1 \| DISEASES 11040 \| PIM2 \| DISEASES 7091 \| TLE4 \| DISEASES 5305 \| PIP4K2A \| DISEASES 780 \| DDR1 \| DISEASES 4524 \| MTHFR \| DISEASES 3133 \| HLA-E \| DISEASES 648 \| BMI1 \| DISEASES 2623 \| GATA1 \| DISEASES 6839 \| SUV39H1 \| DISEASES 7454 \| WAS \| DISEASES 3105 \| HLA-A \| DISEASES 10257 \| ABCC4 \| DISEASES 6723 \| SRM \| DISEASES 160897 \| GPR180 \| DISEASES 54897 \| CASZ1 \| DISEASES 1676 \| DFFA \| DISEASES 84678 \| KDM2B \| DISEASES 114798 \| SLITRK1 \| DISEASES 7056 \| THBD \| DISEASES 5987 \| TRIM27 \| DISEASES 5293 \| PIK3CD \| DISEASES 8366 \| HIST1H4B \| DISEASES 9563 \| H6PD \| DISEASES 3604 \| TNFRSF9 \| DISEASES 688 \| KLF5 \| DISEASES 8346 \| HIST1H2BI \| DISEASES 8361 \| HIST1H4F \| DISEASES 8364 \| HIST1H4C \| DISEASES 6520 \| SLC3A2 \| DISEASES 7403 \| KDM6A \| DISEASES 4609 \| MYC \| DISEASES 57126 \| CD177 \| DISEASES 26586 \| CKAP2 \| DISEASES 1677 \| DFFB \| DISEASES 7161 \| TP73 \| DISEASES 353 \| APRT \| DISEASES 54880 \| BCOR \| DISEASES 7102 \| TSPAN7 \| DISEASES 574028 \| CLLU1 \| DISEASES 3980 \| LIG3 \| DISEASES 1536 \| CYBB \| DISEASES 3963 \| LGALS7 \| DISEASES 2189 \| FANCG \| DISEASES 3400 \| ID4 \| DISEASES 650 \| BMP2 \| DISEASES 64225 \| ATL2 \| DISEASES 9308 \| CD83 \| DISEASES 387923 \| SERP2 \| DISEASES 7293 \| TNFRSF4 \| DISEASES 27000 \| DNAJC2 \| DISEASES 2625 \| GATA3 \| DISEASES 28984 \| RGCC \| DISEASES 1874 \| E2F4 \| DISEASES 3096 \| HIVEP1 \| DISEASES 9636 \| ISG15 \| DISEASES 4739 \| NEDD9 \| DISEASES 6643 \| SNX2 \| DISEASES 2308 \| FOXO1 \| DISEASES 6197 \| RPS6KA3 \| DISEASES 1543 \| CYP1A1 \| DISEASES 2683 \| B4GALT1 \| DISEASES 3301 \| DNAJA1 \| DISEASES 3559 \| IL2RA \| DISEASES 54790 \| TET2 \| DISEASES 7010 \| TEK \| DISEASES 3704 \| ITPA \| DISEASES 675 \| BRCA2 \| DISEASES 4507 \| MTAP \| DISEASES 3440 \| IFNA2 \| DISEASES 3446 \| IFNA10 \| DISEASES 3456 \| IFNB1 \| DISEASES 551 \| AVP \| DISEASES 4300 \| MLLT3 \| DISEASES 6194 \| RPS6 \| DISEASES 284390 \| ZNF763 \| DISEASES 5277 \| PIGA \| DISEASES 833 \| CARS \| DISEASES 8644 \| AKR1C3 \| DISEASES 665 \| BNIP3L \| DISEASES 51284 \| TLR7 \| DISEASES 5272 \| SERPINB9 \| DISEASES 11168 \| PSIP1 \| DISEASES 6541 \| SLC7A1 \| DISEASES 6305 \| SBF1 \| DISEASES 3662 \| IRF4 \| DISEASES 255967 \| PAN3 \| DISEASES 1045 \| CDX2 \| DISEASES 3486 \| IGFBP3 \| DISEASES 415 \| ARSE \| DISEASES 414 \| ARSD \| DISEASES 4267 \| CD99 \| DISEASES 286530 \| P2RY8 \| DISEASES 23081 \| KDM4C \| DISEASES 6443 \| SGCB \| DISEASES 64109 \| CRLF2 \| DISEASES 29126 \| CD274 \| DISEASES 10771 \| ZMYND11 \| DISEASES 257062 \| CATSPERD \| DISEASES 3717 \| JAK2 \| DISEASES 10171 \| RCL1 \| DISEASES 399 \| RHOH \| DISEASES 50808 \| AK3 \| DISEASES 2618 \| GART \| DISEASES 3822 \| KLRC2 \| DISEASES 10188 \| TNK2 \| DISEASES 134218 \| DNAJC21 \| DISEASES 7158 \| TP53BP1 \| DISEASES 83650 \| SLC35G5 \| DISEASES 11200 \| CHEK2 \| DISEASES 4155 \| MBP \| DISEASES 26524 \| LATS2 \| DISEASES 5888 \| RAD51 \| DISEASES 5720 \| PSME1 \| DISEASES 4487 \| MSX1 \| DISEASES 7750 \| ZMYM2 \| DISEASES 645369 \| TMEM200C \| DISEASES 7862 \| BRPF1 \| DISEASES 6419 \| SETMAR \| DISEASES 238 \| ALK \| DISEASES 56254 \| RNF20 \| DISEASES 2175 \| FANCA \| DISEASES 7247 \| TSN \| DISEASES 406 \| ARNTL \| DISEASES 8878 \| SQSTM1 \| DISEASES 440193 \| CCDC88C \| DISEASES 340152 \| ZC3H12D \| DISEASES 6370 \| CCL25 \| DISEASES 3811 \| KIR3DL1 \| DISEASES 3903 \| LAIR1 \| DISEASES 10288 \| LILRB2 \| DISEASES 11009 \| IL24 \| DISEASES 2068 \| ERCC2 \| DISEASES 208 \| AKT2 \| DISEASES 11262 \| SP140 \| DISEASES 7520 \| XRCC5 \| DISEASES 7341 \| SUMO1 \| DISEASES 9244 \| CRLF1 \| DISEASES 55870 \| ASH1L \| DISEASES 3239 \| HOXD13 \| DISEASES 2113 \| ETS1 \| DISEASES 7187 \| TRAF3 \| DISEASES 974 \| CD79B \| DISEASES 4291 \| MLF1 \| DISEASES 10401 \| PIAS3 \| DISEASES 5450 \| POU2AF1 \| DISEASES 838 \| CASP5 \| DISEASES 654364 \| NME1-NME2 \| DISEASES 4831 \| NME2 \| DISEASES 10018 \| BCL2L11 \| DISEASES 8301 \| PICALM \| DISEASES 10840 \| ALDH1L1 \| DISEASES 3660 \| IRF2 \| DISEASES 9130 \| FAM50A \| DISEASES 6733 \| SRPK2 \| DISEASES 4926 \| NUMA1 \| DISEASES 51313 \| FAM198B \| DISEASES 347734 \| SLC35B2 \| DISEASES 3161 \| HMMR \| DISEASES 6494 \| SIPA1 \| DISEASES 9349 \| RPL23 \| DISEASES 57019 \| CIAPIN1 \| DISEASES 5916 \| RARG \| DISEASES 64400 \| AKTIP \| DISEASES 5530 \| PPP3CA \| DISEASES 8697 \| CDC23 \| DISEASES 4145 \| MATK \| DISEASES 6696 \| SPP1 \| DISEASES 4299 \| AFF1 \| DISEASES 983 \| CDK1 \| DISEASES 6046 \| BRD2 \| DISEASES 27040 \| LAT \| DISEASES 3965 \| LGALS9 \| DISEASES 5814 \| PURB \| DISEASES 174 \| AFP \| DISEASES 6387 \| CXCL12 \| DISEASES 5744 \| PTHLH \| DISEASES 2737 \| GLI3 \| DISEASES 4773 \| NFATC2 \| DISEASES 115560 \| ZNF501 \| DISEASES 4629 \| MYH11 \| DISEASES 2120 \| ETV6 \| DISEASES 116135 \| LRRC3B \| DISEASES 7325 \| UBE2E2 \| DISEASES 10521 \| DDX17 \| DISEASES 85403 \| EAF1 \| DISEASES 10379 \| IRF9 \| DISEASES 84433 \| CARD11 \| DISEASES 3676 \| ITGA4 \| DISEASES 4780 \| NFE2L2 \| DISEASES 7757 \| ZNF208 \| DISEASES 7913 \| DEK \| DISEASES 26292 \| MYCBP \| DISEASES 80380 \| PDCD1LG2 \| DISEASES 23365 \| ARHGEF12 \| DISEASES 55174 \| INTS10 \| DISEASES 5609 \| MAP2K7 \| DISEASES 9777 \| TM9SF4 \| DISEASES 729857 \| RGPD2 \| DISEASES 153218 \| SPINK13 \| DISEASES 23150 \| FRMD4B \| DISEASES 4599 \| MX1 \| DISEASES 2950 \| GSTP1 \| DISEASES 84444 \| DOT1L \| DISEASES 23532 \| PRAME \| DISEASES 2887 \| GRB10 \| DISEASES 1859 \| DYRK1A \| DISEASES 3119 \| HLA-DQB1 \| DISEASES 1763 \| DNA2 \| DISEASES 4363 \| ABCC1 \| DISEASES 23243 \| ANKRD28 \| DISEASES 5927 \| KDM5A \| DISEASES 6093 \| ROCK1 \| DISEASES 1654 \| DDX3X \| DISEASES 23028 \| KDM1A \| DISEASES 3803 \| KIR2DL2 \| DISEASES 9612 \| NCOR2 \| DISEASES 8091 \| HMGA2 \| DISEASES 22976 \| PAXIP1 \| DISEASES 1439 \| CSF2RB \| DISEASES 80014 \| WWC2 \| DISEASES 5970 \| RELA \| DISEASES 23077 \| MYCBP2 \| DISEASES 4626 \| MYH8 \| DISEASES 7514 \| XPO1 \| DISEASES 55120 \| FANCL \| DISEASES 8115 \| TCL1A \| DISEASES 60489 \| APOBEC3G \| DISEASES 1994 \| ELAVL1 \| DISEASES 7441 \| VPREB1 \| DISEASES 8995 \| TNFSF18 \| DISEASES 28996 \| HIPK2 \| DISEASES 5150 \| PDE7A \| DISEASES 728441 \| GGT2 \| DISEASES 2011 \| MARK2 \| DISEASES 7018 \| TF \| DISEASES 1052 \| CEBPD \| DISEASES 50489 \| CD207 \| DISEASES 9873 \| FCHSD2 \| DISEASES 29072 \| SETD2 \| DISEASES 200424 \| TET3 \| DISEASES 7852 \| CXCR4 \| DISEASES 3655 \| ITGA6 \| DISEASES 501 \| ALDH7A1 \| DISEASES 3267 \| AGFG1 \| DISEASES 1385 \| CREB1 \| DISEASES 837 \| CASP4 \| DISEASES 1111 \| CHEK1 \| DISEASES 3384 \| ICAM2 \| DISEASES 5601 \| MAPK9 \| DISEASES 3120 \| HLA-DQB2 \| DISEASES 6788 \| STK3 \| DISEASES 55252 \| ASXL2 \| DISEASES 5777 \| PTPN6 \| DISEASES 9564 \| BCAR1 \| DISEASES 3718 \| JAK3 \| DISEASES 3481 \| IGF2 \| DISEASES 5537 \| PPP6C \| DISEASES 8861 \| LDB1 \| DISEASES 6603 \| SMARCD2 \| DISEASES 2260 \| FGFR1 \| DISEASES 3113 \| HLA-DPA1 \| DISEASES 57448 \| BIRC6 \| DISEASES 59339 \| PLEKHA2 \| DISEASES 6503 \| SLA \| DISEASES 1438 \| CSF2RA \| DISEASES 29843 \| SENP1 \| DISEASES 5783 \| PTPN13 \| DISEASES 1029 \| CDKN2A \| DISEASES 23705 \| CADM1 \| DISEASES 26354 \| GNL3 \| DISEASES 64324 \| NSD1 \| DISEASES 1719 \| DHFR \| DISEASES 7155 \| TOP2B \| DISEASES 22809 \| ATF5 \| DISEASES 8848 \| TSC22D1 \| DISEASES 56616 \| DIABLO \| DISEASES 960 \| CD44 \| DISEASES 3702 \| ITK \| DISEASES 7124 \| TNF \| DISEASES 3109 \| HLA-DMB \| DISEASES 3106 \| HLA-B \| DISEASES 6304 \| SATB1 \| DISEASES 10499 \| NCOA2 \| DISEASES 5795 \| PTPRJ \| DISEASES 2130 \| EWSR1 \| DISEASES 387 \| RHOA \| DISEASES 6464 \| SHC1 \| DISEASES 7072 \| TIA1 \| DISEASES 4615 \| MYD88 \| DISEASES 11155 \| LDB3 \| DISEASES 7465 \| WEE1 \| DISEASES 862 \| RUNX1T1 \| DISEASES 6490 \| PMEL \| DISEASES 4049 \| LTA \| DISEASES 64859 \| NABP1 \| DISEASES 26168 \| SENP3 \| DISEASES 54799 \| MBTD1 \| DISEASES 27113 \| BBC3 \| DISEASES 388372 \| CCL4L1 \| DISEASES 79718 \| TBL1XR1 \| DISEASES 5087 \| PBX1 \| DISEASES 5923 \| RASGRF1 \| DISEASES 6613 \| SUMO2 \| DISEASES 3276 \| PRMT1 \| DISEASES 2195 \| FAT1 \| DISEASES 1408 \| CRY2 \| DISEASES 2876 \| GPX1 \| DISEASES 163154 \| PRR22 \| DISEASES 55289 \| ACOXL \| DISEASES 3115 \| HLA-DPB1 \| DISEASES 84106 \| PRAM1 \| DISEASES 121256 \| TMEM132D \| DISEASES 9734 \| HDAC9 \| DISEASES 1012 \| CDH13 \| DISEASES 5578 \| PRKCA \| DISEASES 6349 \| CCL3L1 \| DISEASES 196527 \| ANO6 \| DISEASES 1154 \| CISH \| DISEASES 834 \| CASP1 \| DISEASES 22807 \| IKZF2 \| DISEASES 3925 \| STMN1 \| DISEASES 6424 \| SFRP4 \| DISEASES 64283 \| ARHGEF28 \| DISEASES 7153 \| TOP2A \| DISEASES 1028 \| CDKN1C \| DISEASES 3451 \| IFNA17 \| DISEASES 3586 \| IL10 \| DISEASES 5527 \| PPP2R5C \| DISEASES 84441 \| MAML2 \| DISEASES 112401 \| BIRC8 \| DISEASES 339983 \| NAT8L \| DISEASES 23048 \| FNBP1 \| DISEASES 10043 \| TOM1 \| DISEASES 1945 \| EFNA4 \| DISEASES 54838 \| WBP1L \| DISEASES 23218 \| NBEAL2 \| DISEASES 865 \| CBFB \| DISEASES 8842 \| PROM1 \| DISEASES 6513 \| SLC2A1 \| DISEASES 1849 \| DUSP7 \| DISEASES 4193 \| MDM2 \| DISEASES 3077 \| HFE \| DISEASES 286451 \| YIPF6 \| DISEASES 23089 \| PEG10 \| DISEASES 10243 \| GPHN \| DISEASES 5793 \| PTPRG \| DISEASES 672 \| BRCA1 \| DISEASES 85476 \| GFM1 \| DISEASES 6256 \| RXRA \| DISEASES 1020 \| CDK5 \| DISEASES 8833 \| GMPS \| DISEASES 30816 \| ERVW-1 \| DISEASES 127933 \| UHMK1 \| DISEASES 4345 \| CD200 \| DISEASES 573 \| BAG1 \| DISEASES 220107 \| DLEU7 \| DISEASES 6949 \| TCOF1 \| DISEASES 1452 \| CSNK1A1 \| DISEASES 2638 \| GC \| DISEASES 4043 \| LRPAP1 \| DISEASES 51428 \| DDX41 \| DISEASES 100506742 \| CASP12 \| DISEASES 1977 \| EIF4E \| DISEASES 5238 \| PGM3 \| DISEASES 6196 \| RPS6KA2 \| DISEASES 1050 \| CEBPA \| DISEASES 27 \| ABL2 \| DISEASES 2994 \| GYPB \| DISEASES 64901 \| RANBP17 \| DISEASES 7336 \| UBE2V2 \| DISEASES 284 \| ANGPT1 \| DISEASES 4671 \| NAIP \| DISEASES 4067 \| LYN \| DISEASES 892 \| CCNC \| DISEASES 4603 \| MYBL1 \| DISEASES 2053 \| EPHX2 \| DISEASES 4168 \| MCF2 \| DISEASES 3066 \| HDAC2 \| DISEASES 3620 \| IDO1 \| DISEASES 3551 \| IKBKB \| DISEASES 100423062 \| IGLL5 \| DISEASES 4914 \| NTRK1 \| DISEASES 917 \| CD3G \| DISEASES 7178 \| TPT1 \| DISEASES 56413 \| LTB4R2 \| DISEASES 9774 \| BCLAF1 \| DISEASES 6195 \| RPS6KA1 \| DISEASES 727897 \| MUC5B \| DISEASES 930 \| CD19 \| DISEASES 54682 \| MANSC1 \| DISEASES 83695 \| RHNO1 \| DISEASES 8615 \| USO1 \| DISEASES 1232 \| CCR3 \| DISEASES 3684 \| ITGAM \| DISEASES 4090 \| SMAD5 \| DISEASES 5027 \| P2RX7 \| DISEASES 84707 \| BEX2 \| DISEASES 26150 \| RIBC2 \| DISEASES 8284 \| KDM5D \| DISEASES 3939 \| LDHA \| DISEASES 5125 \| PCSK5 \| DISEASES 3227 \| HOXC11 \| DISEASES 7421 \| VDR \| DISEASES 8972 \| MGAM \| DISEASES 1649 \| DDIT3 \| DISEASES 317 \| APAF1 \| DISEASES 4522 \| MTHFD1 \| DISEASES 51676 \| ASB2 \| DISEASES 56963 \| RGMA \| DISEASES 567 \| B2M \| DISEASES 56917 \| MEIS3 \| DISEASES 101 \| ADAM8 \| DISEASES 4212 \| MEIS2 \| DISEASES 8778 \| SIGLEC5 \| DISEASES 51741 \| WWOX \| DISEASES 3316 \| HSPB2 \| DISEASES 1506 \| CTRL \| DISEASES 4927 \| NUP88 \| DISEASES 26156 \| RSL1D1 \| DISEASES 81033 \| KCNH6 \| DISEASES 9212 \| AURKB \| DISEASES 115727 \| RASGRP4 \| DISEASES 9141 \| PDCD5 \| DISEASES 6209 \| RPS15 \| DISEASES 284424 \| MIR7-3HG \| DISEASES 2323 \| FLT3LG \| DISEASES 6223 \| RPS19 \| DISEASES 246734 \| NPCDR1 \| DISEASES 6689 \| SPIB \| DISEASES 7409 \| VAV1 \| DISEASES 104355217 \| ERICD \| DISEASES 100506311 \| HOTAIRM1 \| DISEASES 104472848 \| IRAIN \| DISEASES 554203 \| JPX \| DISEASES 100885779 \| LINC-ROR \| DISEASES 100499171 \| LINC00276 \| DISEASES 348120 \| LINC01193 \| DISEASES 285758 \| LINC01268 \| DISEASES 100073347 \| MIMT1 \| DISEASES 114614 \| MIR155HG \| DISEASES 407975 \| MIR17HG \| DISEASES 283131 \| NEAT1 \| DISEASES 100169750 \| PRINS \| DISEASES 5820 \| PVT1 \| DISEASES 7955 \| RNF217-AS1 \| DISEASES 106633801 \| SCARNA28 \| DISEASES 677814 \| SNORA31 \| DISEASES 100337591 \| SNORA70F \| DISEASES 692215 \| SNORD112 \| DISEASES 27004 \| TCL6 \| DISEASES 7012 \| TERC \| DISEASES 440288 \| UBL7-AS1 \| DISEASES 100507433 \| ZNF571-AS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	538
Disease	leukemia
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:240) HP:0002664 \| Neoplasia \| 65 HP:0002863 \| Myelodysplastic syndrome \| 53 HP:0002665 \| Lymphoma \| 26 HP:0100242 \| Sarcoma \| 16 HP:0001875 \| Neutropenia \| 14 HP:0001880 \| Eosinophilia \| 13 HP:0004808 \| Acute myelogenous leukemia \| 13 HP:0001873 \| Low platelet count \| 13 HP:0012324 \| Myeloid leukemia \| 13 HP:0005506 \| Chronic myeloid leukemia \| 12 HP:0002721 \| Immunodeficiency \| 12 HP:0005550 \| Chronic lymphatic leukemia \| 12 HP:0006775 \| Multiple myeloma \| 11 HP:0012115 \| Liver inflammation \| 11 HP:0012531 \| Pain \| 11 HP:0002202 \| Pleural effusion \| 10 HP:0001945 \| Fever \| 10 HP:0006721 \| Acute lymphocytic leukemia \| 9 HP:0001903 \| Anemia \| 9 HP:0100806 \| Sepsis \| 8 HP:0012189 \| Hodgkin disease \| 7 HP:0011974 \| Myelofibrosis \| 7 HP:0000083 \| Renal insufficiency \| 7 HP:0001919 \| Acute renal failure \| 6 HP:0030731 \| Carcinoma \| 6 HP:0001876 \| Low blood cell count \| 6 HP:0001878 \| Haemolytic anaemia \| 5 HP:0002090 \| Pneumonia \| 5 HP:0012125 \| Prostate cancer \| 5 HP:0100495 \| Mastocytosis \| 5 HP:0001513 \| Obesity \| 5 HP:0003072 \| Hypercalcemia \| 4 HP:0012325 \| Chronic myelomonocytic leukemia \| 4 HP:0012191 \| B-cell lymphoma \| 4 HP:0012378 \| Fatigue \| 4 HP:0001370 \| Rheumatoid arthritis \| 4 HP:0005521 \| Disseminated intravascular coagulation \| 4 HP:0002013 \| Emesis \| 4 HP:0003002 \| Breast carcinoma \| 4 HP:0001907 \| Thromboembolic disease \| 4 HP:0004836 \| Acute promyelocytic leukemia \| 4 HP:0001974 \| Leukocytosis \| 4 HP:0010885 \| Aseptic necrosis \| 4 HP:0100827 \| Lymphocytosis \| 4 HP:0003256 \| Coagulopathy \| 3 HP:0002170 \| Intracranial hemorrhage \| 3 HP:0002633 \| Vasculitis \| 3 HP:0001067 \| Neurofibromas \| 3 HP:0001733 \| Pancreatic inflammation \| 3 HP:0002960 \| Autoimmune condition \| 3 HP:0001824 \| Weight loss \| 3 HP:0012410 \| Pure red cell aplasia \| 3 HP:0001744 \| Splenomegaly \| 3 HP:0001890 \| Autoimmune hemolytic anemia \| 3 HP:0001973 \| Autoimmune thrombocytopenia \| 3 HP:0001541 \| Ascites \| 3 HP:0000819 \| Diabetes mellitus \| 3 HP:0002653 \| Bone pain \| 3 HP:0001369 \| Arthritis \| 3 HP:0003128 \| Lactic acidosis \| 3 HP:0001941 \| acidemia \| 3 HP:0002027 \| Abdominal pain \| 3 HP:0002017 \| Nausea and vomiting \| 3 HP:0002754 \| Bone infection \| 3 HP:0000873 \| Diabetes insipidus \| 3 HP:0000716 \| Depression \| 3 HP:0005528 \| Bone marrow hypoplasia \| 3 HP:0005549 \| Low blood neutrophil level since birth \| 2 HP:0100280 \| Morbus Crohn \| 2 HP:0000541 \| Detached retina \| 2 HP:0002488 \| Acute leukemias \| 2 HP:0002860 \| Squamous cell carcinoma \| 2 HP:0004387 \| Enterocolitis \| 2 HP:0001009 \| Telangiectases \| 2 HP:0001635 \| Congestive heart failure \| 2 HP:0002573 \| Bloody diarrhea \| 2 HP:0004820 \| Acute myelomonocytic leukemia \| 2 HP:0000709 \| Psychosis \| 2 HP:0002716 \| Lymph node hyperplasia \| 2 HP:0100614 \| Muscle inflammation \| 2 HP:0012190 \| T cell lymphoma \| 2 HP:0010628 \| Facial palsy, unilateral or bilateral \| 2 HP:0000952 \| Yellow skin \| 2 HP:0012743 \| Central obesity \| 2 HP:0004812 \| Pre-B-cell acute lymphoblastic leukemia \| 2 HP:0100543 \| Cognitive deficits \| 2 HP:0000980 \| Pallor \| 2 HP:0000365 \| Hearing impairment \| 2 HP:0002584 \| Intestinal hemorrhage \| 2 HP:0004818 \| Paroxysmal nocturnal hemoglobinuria \| 2 HP:0012393 \| Allergy \| 2 HP:0005387 \| Combined immunodeficiency \| 2 HP:0005523 \| Lymphoproliferative disorder \| 2 HP:0001894 \| Thrombocytosis \| 2 HP:0002583 \| Colitis \| 2 HP:0003473 \| Fatigable weakness \| 2 HP:0000572 \| Visual loss \| 2 HP:0100723 \| Gastrointestinal stroma tumor \| 2 HP:0000407 \| sensorineural hearing loss \| 2 HP:0003074 \| High blood glucose \| 2 HP:0002018 \| Nausea \| 2 HP:0002014 \| Diarrhea \| 2 HP:0002861 \| Melanoma \| 2 HP:0000979 \| Purpura \| 2 HP:0002719 \| infections, recurrent \| 2 HP:0012223 \| Ruptured spleen \| 2 HP:0001287 \| Meningitis \| 2 HP:0012539 \| Non-Hodgkin lymphoma \| 2 HP:0002608 \| Celiac disease \| 2 HP:0004430 \| Severe combined immunodeficiency \| 2 HP:0000488 \| Noninflammatory retina disease \| 1 HP:0100537 \| Inflammation of the fascia \| 1 HP:0001409 \| Portal hypertension \| 1 HP:0002105 \| Hemoptysis \| 1 HP:0012174 \| Glioblastoma multiforme \| 1 HP:0002725 \| Systemic lupus erythematosus \| 1 HP:0001399 \| Liver failure \| 1 HP:0002953 \| Vertebral compression fractures \| 1 HP:0002149 \| Hyperuricemia \| 1 HP:0002315 \| Headaches \| 1 HP:0001510 \| Growth deficiency \| 1 HP:0004349 \| Reduced bone mineral density \| 1 HP:0002835 \| Aspiration \| 1 HP:0001342 \| Intracerebral hemorrhage \| 1 HP:0100796 \| Orchitis \| 1 HP:0003470 \| Inability to move \| 1 HP:0011096 \| Demyelination \| 1 HP:0003073 \| Hypoalbuminaemia \| 1 HP:0001920 \| Renal artery stenosis \| 1 HP:0002148 \| Hypophosphataemia \| 1 HP:0012234 \| Agranulocytosis \| 1 HP:0100523 \| Hepatic abscess \| 1 HP:0012132 \| Erythroid hyperplasia \| 1 HP:0009071 \| Inflammatory myopathy \| 1 HP:0000836 \| Overactive thyroid \| 1 HP:0000739 \| Anxiety \| 1 HP:0001987 \| Hyperammonemia \| 1 HP:0009830 \| Peripheral neuritis \| 1 HP:0000708 \| Behavioral problems \| 1 HP:0012119 \| Methemoglobinemia \| 1 HP:0001263 \| Developmental retardation \| 1 HP:0002243 \| Protein-losing enteropathy \| 1 HP:0003765 \| Psoriasis \| 1 HP:0011034 \| Amyloid disease \| 1 HP:0000845 \| Acromegalic growth \| 1 HP:0002797 \| Increased bone resorption \| 1 HP:0000820 \| Thyroid abnormality \| 1 HP:0001888 \| Lymphocytopenia \| 1 HP:0030746 \| Intraventricular hemorrhage \| 1 HP:0100843 \| Glioblastoma \| 1 HP:0007902 \| Vitreous hemorrhage \| 1 HP:0000771 \| Gynaecomastia \| 1 HP:0003003 \| Colon cancer \| 1 HP:0006554 \| Acute hepatic failure \| 1 HP:0001518 \| Small for gestational age \| 1 HP:0200029 \| Cutaneous vasculitis \| 1 HP:0005681 \| Juvenile idiopathic arthritis \| 1 HP:0001433 \| Enlarged liver and spleen \| 1 HP:0030150 \| Plasmacytosis \| 1 HP:0000871 \| Panhypopituitarism \| 1 HP:0000821 \| Underactive thyroid \| 1 HP:0002039 \| Anorexia \| 1 HP:0200036 \| Skin nodule \| 1 HP:0100658 \| Bacterial infection of skin \| 1 HP:0100778 \| Cryoglobulinemia \| 1 HP:0000939 \| Osteoporosis \| 1 HP:0000501 \| Glaucoma \| 1 HP:0000546 \| Retinal degeneration \| 1 HP:0100008 \| Schwann cell tumour \| 1 HP:0001908 \| Hypoplastic anemia \| 1 HP:0012246 \| Oculomotor nerve palsy \| 1 HP:0004845 \| Acute monoblastic leukemia \| 1 HP:0006744 \| Adrenal carcinoma \| 1 HP:0000969 \| Dropsy \| 1 HP:0003641 \| Hemoglobin in urine \| 1 HP:0100584 \| Endocarditis \| 1 HP:0002019 \| Dyschezia \| 1 HP:0001019 \| Exfoliative dermititis \| 1 HP:0000212 \| Gingival overgrowth \| 1 HP:0012432 \| Chronic fatigue \| 1 HP:0000924 \| Abnormality of the skeletal system \| 1 HP:0001959 \| Polydipsia \| 1 HP:0030069 \| Primary central nervous system lymphoma \| 1 HP:0005547 \| Myeloproliferative disorder \| 1 HP:0001638 \| Cardiomyopathy \| 1 HP:0002239 \| Gastrointestinal hemorrhage \| 1 HP:0006532 \| Pneumonia, recurrent episodes \| 1 HP:0004313 \| Decreased immunoglobulin level \| 1 HP:0030078 \| Lung adenocarcinoma \| 1 HP:0100615 \| Neoplasm of the ovary \| 1 HP:0002894 \| Neoplasia of the pancreas \| 1 HP:0001138 \| Damaged optic nerve \| 1 HP:0004787 \| Fulminant hepatitis \| 1 HP:0000988 \| Exanthem \| 1 HP:0001901 \| Abnormally shaped erythrocytes \| 1 HP:0002113 \| Pulmonary infiltrates \| 1 HP:0002667 \| Wilms tumor \| 1 HP:0003198 \| Myopathic changes \| 1 HP:0009792 \| Teratoma \| 1 HP:0002671 \| Basalioma \| 1 HP:0000103 \| Polyuria \| 1 HP:0040184 \| Oral hemorrhage \| 1 HP:0010447 \| Fistula in ano \| 1 HP:0001114 \| Fatty deposits on eyelids \| 1 HP:0002155 \| Increased triglycerides \| 1 HP:0000105 \| Renal enlargement \| 1 HP:0003287 \| Abnormality of mitochondrial metabolism \| 1 HP:0012312 \| Low blood monocyte number \| 1 HP:0012398 \| Peripheral edema \| 1 HP:0001696 \| Situs inversus totalis \| 1 HP:0001082 \| Cholecystitis \| 1 HP:0001972 \| Macrocytic anemia \| 1 HP:0001915 \| Aplastic anemia \| 1 HP:0006515 \| Interstitial pneumonitis \| 1 HP:0002383 \| Encephalitis \| 1 HP:0012254 \| Ewing's sarcoma \| 1 HP:0002617 \| Aneurysmal dilatation \| 1 HP:0000529 \| Slowly progressive visual loss \| 1 HP:0100726 \| Kaposi's sarcoma \| 1 HP:0002625 \| Blood clot in a deep vein \| 1 HP:0012636 \| Retinal vein occlusion \| 1 HP:0001250 \| Seizures \| 1 HP:0002859 \| Rhabdomyosarcoma \| 1 HP:0001251 \| Ataxia \| 1 HP:0000863 \| Neurohypophyseal diabetes insipidus \| 1 HP:0030149 \| Cardiovascular shock \| 1 HP:0100279 \| Ulcerative colitis \| 1 HP:0000822 \| Hypertension \| 1 HP:0006562 \| Viral hepatitis \| 1 HP:0009763 \| Limb pain \| 1 HP:0000246 \| Sinus inflammation \| 1 HP:0011695 \| Cerebellar hemorrhage \| 1 HP:0030242 \| Blood clot in portal vein \| 1 HP:0012578 \| Membranous glomerulonephritis \| 1 HP:0012315 \| Histiocytoma \| 1 HP:0002385 \| Paraparesis \| 1 HP:0003006 \| Neuroblastoma \| 1 HP:0001658 \| Myocardial infarction \| 1 HP:0002098 \| Respiratory distress \| 1 HP:0100769 \| Synovitis \| 1

Disease ID	538
Disease	leukemia
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:74) C0009450 \| infection \| 78 C0796095 \| c syndrome \| 26 C0021311 \| infections \| 25 C0005699 \| blast crisis \| 24 C0040034 \| thrombocytopenia \| 13 C0015967 \| fever \| 10 C0021051 \| immunodeficiency \| 9 C0002871 \| anemia \| 9 C0019080 \| hemorrhage \| 9 C0042769 \| virus infection \| 9 C0040053 \| thrombosis \| 9 C0036690 \| sepsis \| 8 C0004030 \| aspergillosis \| 8 C0026946 \| fungal infection \| 8 C0426768 \| o sign \| 7 C0035078 \| renal failure \| 7 C0152276 \| chloroma \| 5 C0028754 \| obesity \| 5 C0032285 \| pneumonia \| 5 C0002878 \| hemolytic anemia \| 5 C0012739 \| disseminated intravascular coagulation \| 4 C0026946 \| fungal disease \| 4 C0036690 \| septicemia \| 4 C0004610 \| bacteremia \| 4 C0018133 \| graft-versus-host disease \| 4 C0020437 \| hypercalcemia \| 4 C1608408 \| malignant transformation \| 4 C0011848 \| diabetes insipidus \| 3 C0008625 \| chromosomal abnormality \| 3 C0029166 \| oral manifestation \| 3 C0041296 \| tuberculosis \| 3 C0029166 \| oral manifestations \| 3 C0011570 \| depression \| 3 C0746883 \| febrile neutropenia \| 3 C0021400 \| influenza \| 3 C0231303 \| distress \| 3 C0003864 \| arthritis \| 3 C0037198 \| sinus thrombosis \| 2 C0008049 \| varicella \| 2 C0026946 \| fungal infections \| 2 C0010346 \| crohn's disease \| 2 C0026718 \| mucormycosis \| 2 C1704231 \| neoplastic meningitis \| 2 C0022346 \| jaundice \| 2 C0025289 \| meningitis \| 2 C0004364 \| autoimmune disease \| 2 C0243026 \| systemic infection \| 1 C0878544 \| cardiomyopathy \| 1 C2350529 \| pulmonary aspergillosis \| 1 C0272412 \| splenic abscess \| 1 C0010823 \| cytomegalovirus infection \| 1 C0876973 \| pulmonary infection \| 1 C0006840 \| candida infection \| 1 C0024312 \| lymphopenia \| 1 C0740394 \| hyperuricemia \| 1 C0009450 \| infectious diseases \| 1 C0006840 \| candidiasis \| 1 C0035309 \| retinopathy \| 1 C0021308 \| infarction \| 1 C0037284 \| skin lesions \| 1 C0155550 \| neural hearing loss \| 1 C0151332 \| active tuberculosis \| 1 C0343885 \| chronic disseminated candidiasis \| 1 C0037274 \| dermatoses \| 1 C0042769 \| viral infections \| 1 C0024228 \| adenopathy \| 1 C0235896 \| pulmonary infiltrates \| 1 C0011606 \| erythroderma \| 1 C0007642 \| cellulitis \| 1 C0021079 \| immunosuppression \| 1 C0752303 \| urological manifestations \| 1 C0154841 \| central retinal vein occlusion \| 1 C0085082 \| fungemia \| 1 C0022116 \| ischemia \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:104)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1045642	23731124	5243	ABCB1	umls:C0023418	BeFree	Association between the MDR1 gene variant C3435T and risk of leukaemia: a meta-analysis.	0.054740296	2013	ABCB1	7	87509329	A	T,G
rs1045642	22088099	5243	ABCB1	umls:C0023418	BeFree	Variant genotypes of MDR1 C3435T increase the risk of leukemia: evidence from 10 case-control studies.	0.054740296	2012	ABCB1	7	87509329	A	T,G
rs10821936	24564228	84159	ARID5B	umls:C0023418	BeFree	The heterozygous genotype in ARID5B rs10821936 increased the risk for MLL-r leukemia in both white and non-white (OR 2.06, 95% CI: 1.12-3.79 and OR 2.36, 95% CI: 1.09-5.10, respectively).	0.002638474	2014	ARID5B	10	61963818	C	T
rs10821936	24564228	4297	KMT2A	umls:C0023418	BeFree	The heterozygous genotype in ARID5B rs10821936 increased the risk for MLL-r leukemia in both white and non-white (OR 2.06, 95% CI: 1.12-3.79 and OR 2.36, 95% CI: 1.09-5.10, respectively).	0.240150617	2014	ARID5B	10	61963818	C	T
rs11203366	17216583	23569	PADI4	umls:C0023418	BeFree	The functional haplotype of peptidylarginine deiminase IV (S55G, A82V and A112G) associated with susceptibility to rheumatoid arthritis dominates apoptosis of acute T leukemia Jurkat cells.	0.002995792	2007	PADI4	1	17331039	G	A
rs11203367	17216583	23569	PADI4	umls:C0023418	BeFree	The functional haplotype of peptidylarginine deiminase IV (S55G, A82V and A112G) associated with susceptibility to rheumatoid arthritis dominates apoptosis of acute T leukemia Jurkat cells.	0.002995792	2007	PADI4	1	17331121	T	C
rs113488022	24433452	673	BRAF	umls:C0023418	BeFree	Alternative BRAF mutations in BRAF V600E-negative hairy cell leukaemias.	0.002442977	2013	BRAF	7	140753336	A	T,G,C
rs113488022	22553924	673	BRAF	umls:C0023418	BeFree	We identified a novel breakpoint region at 14q32.13 that was rearranged together with IGH/14q32.33 in four cases of BRAF/V600E-negative leukemia/lymphoma with villous lymphocytes carrying either t(14;14)(q32.13;q32.33) (three patients) or del(14)(q32.13q32.33) (one patient).	0.002442977	2012	BRAF	7	140753336	A	T,G,C
rs113488022	23349307	5594	MAPK1	umls:C0023418	BeFree	We assessed phospho-ERK expression in 37 patients with hairy cell leukemia and 44 patients with neoplasms mimicking hairy cell leukemia (40 splenic marginal zone lymphoma, 2 hairy cell leukemia-variant and 2 splenic lymphoma/leukemia unclassifiable) using immunohistochemistry on routine biopsies and/or Western blotting on purified leukemic cells, and correlated the phospho-ERK status with the BRAF-V600E mutation status.	0.007077352	2013	BRAF	7	140753336	A	T,G,C
rs113488022	24717435	673	BRAF	umls:C0023418	BeFree	The BRAF kinase is mutated, typically Val 600→Glu (V600E), to induce an active oncogenic state in a large fraction of melanomas, thyroid cancers, hairy cell leukaemias and, to a smaller extent, a wide spectrum of other cancers.	0.002442977	2014	BRAF	7	140753336	A	T,G,C
rs113488022	25480661	673	BRAF	umls:C0023418	BeFree	BRAF-V600E is the key driver mutation in HCL and distinguishes it from other B-cell lymphomas, including HCL-like leukemias/lymphomas (HCL-variant and splenic marginal zone lymphoma).	0.002442977	2015	BRAF	7	140753336	A	T,G,C
rs113488022	25120816	673	BRAF	umls:C0023418	BeFree	All 12 cases of HCL showed cytoplasmic BRAF V600E protein expression in leukemia cells by immunohistochemical study regardless of tumor burden, whereas all cases of HCL mimics including HCL-v, SMZL, and MZL were negative for BRAF V600E protein.	0.002442977	2014	BRAF	7	140753336	A	T,G,C
rs113488022	23349307	2048	EPHB2	umls:C0023418	BeFree	We assessed phospho-ERK expression in 37 patients with hairy cell leukemia and 44 patients with neoplasms mimicking hairy cell leukemia (40 splenic marginal zone lymphoma, 2 hairy cell leukemia-variant and 2 splenic lymphoma/leukemia unclassifiable) using immunohistochemistry on routine biopsies and/or Western blotting on purified leukemic cells, and correlated the phospho-ERK status with the BRAF-V600E mutation status.	0.000814326	2013	BRAF	7	140753336	A	T,G,C
rs113488022	21663470	673	BRAF	umls:C0023418	BeFree	None of the 195 patients with other peripheral B-cell lymphomas or leukemias who were evaluated carried the BRAF V600E variant, including 38 patients with splenic marginal-zone lymphomas or unclassifiable splenic lymphomas or leukemias.	0.002442977	2011	BRAF	7	140753336	A	T,G,C
rs11547328	12731669	1019	CDK4	umls:C0023418	BeFree	Absence of R24C mutation of the CDK4 gene in leukemias and solid tumors.	0.002442977	2003	CDK4;MARCH9	12	57751648	G	A
rs121434592	19461960	207	AKT1	umls:C0023418	BeFree	The E17K change results in constitutive AKT1 activation, induces leukaemia in mice, and accordingly, may be therapeutically exploited to target the PI3K pathway.	0.011420422	2009	AKT1	14	104780214	C	T
rs121434592	19461960	5291	PIK3CB	umls:C0023418	BeFree	The E17K change results in constitutive AKT1 activation, induces leukaemia in mice, and accordingly, may be therapeutically exploited to target the PI3K pathway.	0.005428837	2009	AKT1	14	104780214	C	T
rs121434592	19461960	5293	PIK3CD	umls:C0023418	BeFree	The E17K change results in constitutive AKT1 activation, induces leukaemia in mice, and accordingly, may be therapeutically exploited to target the PI3K pathway.	0.005428837	2009	AKT1	14	104780214	C	T
rs121434592	19461960	5290	PIK3CA	umls:C0023418	BeFree	The E17K change results in constitutive AKT1 activation, induces leukaemia in mice, and accordingly, may be therapeutically exploited to target the PI3K pathway.	0.005971721	2009	AKT1	14	104780214	C	T
rs121434592	19461960	5294	PIK3CG	umls:C0023418	BeFree	The E17K change results in constitutive AKT1 activation, induces leukaemia in mice, and accordingly, may be therapeutically exploited to target the PI3K pathway.	0.00842463	2009	AKT1	14	104780214	C	T
rs121434592	18665177	207	AKT1	umls:C0023418	BeFree	The transforming mutation E17K/AKT1 is not a major event in B-cell-derived lymphoid leukaemias.	0.011420422	2008	AKT1	14	104780214	C	T
rs121434592	17921701	207	AKT1	umls:C0023418	BeFree	They described a novel point mutation (E17K) in the pleckstrin homology domain (PHD) of the AKT1 gene in human breast, colorectal and ovarian cancers, and demonstrated that it induces leukemia in mice.	0.011420422	2007	AKT1	14	104780214	C	T
rs121434592	20440266	207	AKT1	umls:C0023418	BeFree	Recently, the E17K mutation in the AKT1 has been associated with multiple human malignancies and leukemia in mice.	0.011420422	2010	AKT1	14	104780214	C	T
rs121434592	18504432	207	AKT1	umls:C0023418	BeFree	The E17K change results in constitutive AKT1 activation and induces leukaemia in mice.	0.011420422	2008	AKT1	14	104780214	C	T
rs121912438	12967646	6647	SOD1	umls:C0023418	BeFree	The effect of leukaemia inhibitory factor on SOD1 G93A murine amyotrophic lateral sclerosis.	0.003267234	2003	SOD1	21	31667299	G	C
rs121913227	24589925	4893	NRAS	umls:C0023418	BeFree	In a patient with a BRAF(V600K)-mutant melanoma responding to vemurafenib, we observed accelerated progression of a previously unrecognized NRAS-mutant leukemia.	0.004885954	2015	NA	NA	NA	NA	NA
rs121913237	25316678	5609	MAP2K7	umls:C0023418	BeFree	NRAS(G12V) maintained leukemia self-renewal through mTOR and MEK pathway activation, implicating these pathways as potential targets for cancer stem cell-specific therapies.	0.001628651	2015	NRAS	1	114716126	C	T,G,A
rs121913237	25316678	4893	NRAS	umls:C0023418	BeFree	NRAS(G12V) maintained leukemia self-renewal through mTOR and MEK pathway activation, implicating these pathways as potential targets for cancer stem cell-specific therapies.	0.004885954	2015	NRAS	1	114716126	C	T,G,A
rs121913237	21163920	4893	NRAS	umls:C0023418	BeFree	Injecting Mx1-Cre, LSL-Nras(G12D) mice with the MOL4070LTR retrovirus causes acute myeloid leukemia that faithfully recapitulates many aspects of human NRAS-associated leukemias, including cooperation with deregulated Evi1 expression.	0.004885954	2011	NRAS	1	114716126	C	T,G,A
rs121913237	25316678	3689	ITGB2	umls:C0023418	BeFree	In a multiplexed analysis of RAS-dependent signaling, Mac-1(Low) cells, which harbor leukemia stem cells, were preferentially sensitive to NRAS(G12V) withdrawal.	0.000814326	2015	NRAS	1	114716126	C	T,G,A
rs121913237	25316678	4297	KMT2A	umls:C0023418	BeFree	Using computational approaches to explore our gene-expression data sets, we found that NRAS(G12V) enforced the leukemia self-renewal gene-expression signature and was required to maintain an MLL-AF9- and Myb-dependent leukemia self-renewal gene-expression program.	0.240150617	2015	NRAS	1	114716126	C	T,G,A
rs121913237	25316678	3684	ITGAM	umls:C0023418	BeFree	In a multiplexed analysis of RAS-dependent signaling, Mac-1(Low) cells, which harbor leukemia stem cells, were preferentially sensitive to NRAS(G12V) withdrawal.	0.001357209	2015	NRAS	1	114716126	C	T,G,A
rs121913448	15194504	25	ABL1	umls:C0023418	BeFree	The resistance to the tyrosine kinase inhibitor imatinib in BCR/ABL-positive leukemias is mostly associated with mutations in the kinase domain of BCR/ABL, which include the most prevalent mutations E255K and T315I.	0.089268157	2004	ABL1	9	130862976	G	A
rs121913459	25686603	3791	KDR	umls:C0023418	BeFree	Here we combine comprehensive drug sensitivity and resistance profiling of patient cells ex vivo with structural analysis to establish the VEGFR tyrosine kinase inhibitor axitinib as a selective and effective inhibitor for T315I-mutant BCR-ABL1-driven leukaemia.	0.004353001	2014	ABL1	9	130872896	C	T
rs121913459	22985168	25	ABL1	umls:C0023418	BeFree	Given the fact that all AKIs fail to inhibit BCR/ABL harboring the 'gatekeeper' mutation T315I, we investigated the effects of AKIs in combination with the allosteric inhibitor GNF2 in Ph + leukemia.	0.089268157	2012	ABL1	9	130872896	C	T
rs121913459	21926354	25	ABL1	umls:C0023418	BeFree	Allogeneic stem cell transplantation for patients harboring T315I BCR-ABL mutated leukemias.	0.089268157	2011	ABL1	9	130872896	C	T
rs121913459	25394714	25	ABL1	umls:C0023418	BeFree	PF-114, a potent and selective inhibitor of native and mutated BCR/ABL is active against Philadelphia chromosome-positive (Ph+) leukemias harboring the T315I mutation.	0.089268157	2014	ABL1	9	130872896	C	T
rs121913459	25686603	613	BCR	umls:C0023418	BeFree	Here we combine comprehensive drug sensitivity and resistance profiling of patient cells ex vivo with structural analysis to establish the VEGFR tyrosine kinase inhibitor axitinib as a selective and effective inhibitor for T315I-mutant BCR-ABL1-driven leukaemia.	0.051753097	2014	ABL1	9	130872896	C	T
rs121913459	17671436	3320	HSP90AA1	umls:C0023418	BeFree	We recently showed that inhibition of heat shock protein 90 (Hsp90) by a novel Hsp90 inhibitor, IPI- 504, causes BCR-ABL protein degradation, decreased numbers of leukemia stem cells, and prolonged survival of mice with CML induced by BCR-ABL-T315I.	0.003800186	2007	ABL1	9	130872896	C	T
rs121913459	22772060	25	ABL1	umls:C0023418	BeFree	MK-0457, an Aurora kinase and BCR-ABL inhibitor, is active in patients with BCR-ABL T315I leukemia.	0.089268157	2013	ABL1	9	130872896	C	T
rs121913459	23190221	25	ABL1	umls:C0023418	BeFree	Ponatinib was highly active in heavily pretreated patients with Ph-positive leukemias with resistance to tyrosine kinase inhibitors, including patients with the BCR-ABL T315I mutation, other mutations, or no mutations.	0.089268157	2012	ABL1	9	130872896	C	T
rs121913459	25686603	25	ABL1	umls:C0023418	BeFree	Here we combine comprehensive drug sensitivity and resistance profiling of patient cells ex vivo with structural analysis to establish the VEGFR tyrosine kinase inhibitor axitinib as a selective and effective inhibitor for T315I-mutant BCR-ABL1-driven leukaemia.	0.089268157	2014	ABL1	9	130872896	C	T
rs121913459	15194504	25	ABL1	umls:C0023418	BeFree	The resistance to the tyrosine kinase inhibitor imatinib in BCR/ABL-positive leukemias is mostly associated with mutations in the kinase domain of BCR/ABL, which include the most prevalent mutations E255K and T315I.	0.089268157	2004	ABL1	9	130872896	C	T
rs121913459	19366808	25	ABL1	umls:C0023418	BeFree	Thus, sorafenib may provide an effective therapeutic measure to treat Ph+ leukemias, particularly those expressing the T315I mutant, which is totally resistant to imatinib and the second generation BCR/ABL inhibitors.	0.089268157	2009	ABL1	9	130872896	C	T
rs121913507	20553795	3815	KIT	umls:C0023418	BeFree	In most patients with systemic mastocytosis (SM), including aggressive SM (ASM) and mast cell (MC) leukemia (MCL), neoplastic cells express the oncogenic KIT mutation D816V, which confers resistance to imatinib.	0.018673407	2010	KIT	4	54733155	A	T
rs121913507	18986703	3815	KIT	umls:C0023418	BeFree	Additionally, dasatinib induced apoptosis in mast cell and leukemia cell lines expressing KIT(D816V).	0.018673407	2009	KIT	4	54733155	A	T
rs121913507	19804454	3815	KIT	umls:C0023418	BeFree	Two subclones of the HMC1 mast leukaemia cell line were used; both express an identical KIT allele-specific regulatory type mutation (V560G), but differ in that one also expresses an enzymatic site type mutation (D816V) that confers on them resistance to imatinib mesylate tyrosine kinase inhibitor.	0.018673407	2010	KIT	4	54733155	A	T
rs121913514	22101339	862	RUNX1T1	umls:C0023418	BeFree	Here we studied the effects of Bacillus intermedius RNase (binase) on murine myeloid progenitor cells FDC-P1; transduced FDC-P1 cells ectopically expressing mutated human KIT N822K oncogene and/or human AML1-ETO oncogene; and human leukemia Kasumi-1 cells expressing both of these oncogenes.	0.035337101	2011	KIT	4	54733174	T	A
rs121913514	22101339	1218	CMD1B	umls:C0023418	BeFree	Here we studied the effects of Bacillus intermedius RNase (binase) on murine myeloid progenitor cells FDC-P1; transduced FDC-P1 cells ectopically expressing mutated human KIT N822K oncogene and/or human AML1-ETO oncogene; and human leukemia Kasumi-1 cells expressing both of these oncogenes.	0.000271442	2011	KIT	4	54733174	T	A
rs121913514	22101339	861	RUNX1	umls:C0023418	BeFree	Here we studied the effects of Bacillus intermedius RNase (binase) on murine myeloid progenitor cells FDC-P1; transduced FDC-P1 cells ectopically expressing mutated human KIT N822K oncogene and/or human AML1-ETO oncogene; and human leukemia Kasumi-1 cells expressing both of these oncogenes.	0.115088437	2011	KIT	4	54733174	T	A
rs121913514	22101339	3815	KIT	umls:C0023418	BeFree	Here we studied the effects of Bacillus intermedius RNase (binase) on murine myeloid progenitor cells FDC-P1; transduced FDC-P1 cells ectopically expressing mutated human KIT N822K oncogene and/or human AML1-ETO oncogene; and human leukemia Kasumi-1 cells expressing both of these oncogenes.	0.018673407	2011	KIT	4	54733174	T	A
rs121913514	22101339	3902	LAG3	umls:C0023418	BeFree	Here we studied the effects of Bacillus intermedius RNase (binase) on murine myeloid progenitor cells FDC-P1; transduced FDC-P1 cells ectopically expressing mutated human KIT N822K oncogene and/or human AML1-ETO oncogene; and human leukemia Kasumi-1 cells expressing both of these oncogenes.	0.000271442	2011	KIT	4	54733174	T	A
rs121913517	19804454	3815	KIT	umls:C0023418	BeFree	Two subclones of the HMC1 mast leukaemia cell line were used; both express an identical KIT allele-specific regulatory type mutation (V560G), but differ in that one also expresses an enzymatic site type mutation (D816V) that confers on them resistance to imatinib mesylate tyrosine kinase inhibitor.	0.018673407	2010	KIT	4	54727444	T	A,C,G
rs121913521	19804454	3815	KIT	umls:C0023418	BeFree	Two subclones of the HMC1 mast leukaemia cell line were used; both express an identical KIT allele-specific regulatory type mutation (V560G), but differ in that one also expresses an enzymatic site type mutation (D816V) that confers on them resistance to imatinib mesylate tyrosine kinase inhibitor.	0.018673407	2010	KIT	4	54727447	T	A,G
rs121913615	19194467	4352	MPL	umls:C0023418	BeFree	We conclude that MPL(W515L) occurs in a considerable proportion of acute megakaryoblastic leukaemias with myelofibrosis unrelated to PMF.	0.005167327	2009	MPL	1	43349338	G	T
rs121918464	23884424	5781	PTPN11	umls:C0023418	BeFree	Here, we report that induction of the Ptpn11(E76K/+) mutation, the most common and active Ptpn11 mutation found in leukemias and solid tumors, in primary mouse embryonic fibroblasts resulted in proliferative arrest and premature senescence.	0.136697369	2014	PTPN11	12	112450406	G	A,C
rs16754	21659357	7490	WT1	umls:C0023418	BeFree	Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.	0.142840843	2011	WT1	11	32396399	T	C
rs17166050	24093751	10111	RAD50	umls:C0023418	BeFree	The frequency of either the AA genotype or A allele of RAD50_rs17166050 were significantly different in controls compared to leukemia group (ALL+AML) (p<0.0019 and p<0.0019, respectively).	0.000271442	2013	RAD50	5	132579521	G	A
rs17433222	20438785	714	C1QC	umls:C0023418	GAD	[Polymorphisms in innate immunity genes and risk of childhood leukemia.]	0.002367032	2010	C1QB	1	22652153	G	A
rs1800562	15775751	3077	HFE	umls:C0023418	BeFree	Given the population frequency of C282Y and the connection between iron and cancer, clarification of the mechanism of HFE associations in leukemia and cancer will have strong implications in public health.	0.015645278	2005	HFE	6	26092913	G	A
rs1800566	22976839	5444	PON1	umls:C0023418	BeFree	The NQO1 rs1800566 (C609T), PON1 rs854560 (L55M), and PON1 rs662 (Q192R) polymorphisms modified risk depending on leukemia subtype (decreased in AML, increased and decreased in ALL, respectively), age strata, and variant genotype combinations.	0.000271442	2012	NQO1	16	69711242	G	A
rs1800566	22976839	1728	NQO1	umls:C0023418	BeFree	The NQO1 rs1800566 (C609T), PON1 rs854560 (L55M), and PON1 rs662 (Q192R) polymorphisms modified risk depending on leukemia subtype (decreased in AML, increased and decreased in ALL, respectively), age strata, and variant genotype combinations.	0.023808397	2012	NQO1	16	69711242	G	A
rs1800566	24571676	1728	NQO1	umls:C0023418	BeFree	RAS mutations in early age leukaemia modulated by NQO1 rs1800566 (C609T) are associated with second-hand smoking exposures.	0.023808397	2014	NQO1	16	69711242	G	A
rs1801394	24261678	4552	MTRR	umls:C0023418	BeFree	Methionine synthase reductase A66G polymorphism and leukemia risk: evidence from published studies.	0.007729856	2015	MTRR;FASTKD3	5	7870860	A	G
rs1801394	24261678	4548	MTR	umls:C0023418	BeFree	The MTRR A66G (rs1801394) polymorphism is found to be associated with decreased enzyme affinity for MTR, the gene that encodes MS, and has been widely investigated for cancer risk, including leukemia.	0.002638474	2015	MTRR;FASTKD3	5	7870860	A	G
rs1805373	17651912	4968	OGG1	umls:C0023418	BeFree	A novel R229Q OGG1 polymorphism results in a thermolabile enzyme that sensitizes KG-1 leukemia cells to DNA damaging agents.	0.003267234	2007	OGG1	3	9754824	G	A
rs2032582	24142546	5243	ABCB1	umls:C0023418	BeFree	Association of MDR1 G2677T polymorphism and leukemia risk: evidence from a meta-analysis.	0.054740296	2013	ABCB1	7	87531302	A	T,C
rs2413739	22846425	11252	PACSIN2	umls:C0023418	BeFree	The association of a PACSIN2 SNP (rs2413739) with TPMT activity was confirmed in patients and knock-down of PACSIN2 mRNA in human leukemia cells (NALM6) resulted in significantly lower TPMT activity.	0.000271442	2012	PACSIN2	22	43001030	C	T
rs2413739	22846425	7172	TPMT	umls:C0023418	BeFree	The association of a PACSIN2 SNP (rs2413739) with TPMT activity was confirmed in patients and knock-down of PACSIN2 mRNA in human leukemia cells (NALM6) resulted in significantly lower TPMT activity.	0.020836349	2012	PACSIN2	22	43001030	C	T
rs25487	23990457	7515	XRCC1	umls:C0023418	BeFree	XRCC1 Arg399Gln variation and leukemia susceptibility: evidence from 2,647 cases and 5,518 controls.	0.015916719	2013	XRCC1	19	43551574	T	C
rs25487	25619474	7515	XRCC1	umls:C0023418	BeFree	The current meta-analysis indicated that the Arg399Gln polymorphism in the XRCC1 gene might be a risk factor for hematological malignancies in Asians or for leukemia.	0.015916719	2014	XRCC1	19	43551574	T	C
rs28933375	15755897	5551	PRF1	umls:C0023418	BeFree	In this study, we expressed wild-type and mutated perforin in rat basophil leukemia cells to study the effect on lytic function of the substitutions A91V and N252S (commonly considered to be neutral polymorphisms) and 22 perforin missense substitutions first identified in HLH patients.	0.001900093	2005	PRF1	10	70598966	T	C
rs35602083	16320249	2322	FLT3	umls:C0023418	BeFree	Our data suggest that the FLT3 D324N variant might be associated with a predisposition to different subtypes of leukemia.	0.093278617	2006	FLT3	13	28049450	C	T
rs35947132	15755897	5551	PRF1	umls:C0023418	BeFree	In this study, we expressed wild-type and mutated perforin in rat basophil leukemia cells to study the effect on lytic function of the substitutions A91V and N252S (commonly considered to be neutral polymorphisms) and 22 perforin missense substitutions first identified in HLH patients.	0.001900093	2005	PRF1	10	70600631	G	A
rs368647662	15967214	7296	TXNRD1	umls:C0023418	BeFree	Further, at least two studies now show that the inactivating NAD(P)H:quinone acceptor oxidoreductase (NQO1) C609T polymorphism is positively associated with leukemias arising in the first 1-2 years of life and polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene have been associated with adult and childhood ALL.	0.000271442	2005	TXNRD1	12	104265777	C	T
rs368647662	15967214	4524	MTHFR	umls:C0023418	BeFree	Further, at least two studies now show that the inactivating NAD(P)H:quinone acceptor oxidoreductase (NQO1) C609T polymorphism is positively associated with leukemias arising in the first 1-2 years of life and polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene have been associated with adult and childhood ALL.	0.047207275	2005	TXNRD1	12	104265777	C	T
rs370216745	21073132	1728	NQO1	umls:C0023418	BeFree	Our results suggest that increased risk of infant leukemia development in patients with NQO1 13 polymorphism is partially dependent on the inhibition of p53 pathway, though further studies are needed to fully understand the pathological role of C465T variant in the development of childhood leukemia.	0.023808397	2010	TP53	17	7674949	A	G
rs370216745	21073132	7157	TP53	umls:C0023418	BeFree	Our results suggest that increased risk of infant leukemia development in patients with NQO1 13 polymorphism is partially dependent on the inhibition of p53 pathway, though further studies are needed to fully understand the pathological role of C465T variant in the development of childhood leukemia.	0.057201797	2010	TP53	17	7674949	A	G
rs3794845	20438785	4155	MBP	umls:C0023418	GAD	[Polymorphisms in innate immunity genes and risk of childhood leukemia.]	0.002367032	2010	MBP	18	77002561	G	C
rs386493716	25619474	7515	XRCC1	umls:C0023418	BeFree	The current meta-analysis indicated that the Arg399Gln polymorphism in the XRCC1 gene might be a risk factor for hematological malignancies in Asians or for leukemia.	0.015916719	2014	NA	NA	NA	NA	NA
rs386493716	23990457	7515	XRCC1	umls:C0023418	BeFree	XRCC1 Arg399Gln variation and leukemia susceptibility: evidence from 2,647 cases and 5,518 controls.	0.015916719	2013	NA	NA	NA	NA	NA
rs386626619	21326037	4352	MPL	umls:C0023418	BeFree	Mutations in the thrombopoietin receptor gene (myeloproliferative leukemia, MPL) have been reported in patients with JAK2 V617F-negative chronic myeloproliferative disorders (MPDs).	0.005167327	2011	NA	NA	NA	NA	NA
rs386626619	25479752	4297	KMT2A	umls:C0023418	BeFree	In mice, tamoxifen treatment blocked development of JAK2(V617F)-induced myeloproliferative neoplasm in vivo, induced apoptosis of human JAK2(V617F+) HSPCs in a xenograft model, and sensitized MLL-AF9(+) leukemias to chemotherapy.	0.240150617	2014	NA	NA	NA	NA	NA
rs386626619	23432162	3717	JAK2	umls:C0023418	BeFree	Continued research into how miRNAs impact JAK2(V617F) clonal expansion, differential haematopoiesis among different MPNs, disease progression and leukaemia transformation will lead to a better understanding of the development of these disorders, their clinical manifestations, and their treatment.	0.144970109	2013	NA	NA	NA	NA	NA
rs386626619	19691103	3717	JAK2	umls:C0023418	BeFree	JAK2 (V617F)-positive ET may evolve in few instances into JAK2-negative leukemia.	0.144970109	2009	NA	NA	NA	NA	NA
rs386626619	21712540	3717	JAK2	umls:C0023418	BeFree	Among the patients with myelofibrosis, those with ASXL1 lesions were not distinguished from their wild-type counterparts with regard to JAK2 V617F status, exposure to chemotherapy or evolution to leukemia.	0.144970109	2011	NA	NA	NA	NA	NA
rs387906517	15194504	25	ABL1	umls:C0023418	BeFree	The resistance to the tyrosine kinase inhibitor imatinib in BCR/ABL-positive leukemias is mostly associated with mutations in the kinase domain of BCR/ABL, which include the most prevalent mutations E255K and T315I.	0.089268157	2004	ABL1	9	130862919	G	A
rs387906553	12384420	1991	ELANE	umls:C0023418	BeFree	Collectively, these data suggest that expression of V72M NE is not sufficient to induce an SCN phenotype or leukemia in mice.	0.001357209	2002	ELANE	19	853022	G	A
rs387906666	25939664	867	CBL	umls:C0023418	BeFree	The penetrance of the CBL Y371C mutation was 30% for JMML and 40% for all leukemia.	0.000814326	2015	CBL	11	119278182	A	G
rs387907272	26230596	4615	MYD88	umls:C0023418	BeFree	Significance of MYD88 L265P Mutation Status in the Subclassification of Low-Grade B-Cell Lymphoma/Leukemia.	0.000271442	2015	MYD88	3	38141150	T	C
rs397507444	16182363	4524	MTHFR	umls:C0023418	BeFree	Our investigation provides interesting data concerning the opposite effect of A1298C polymorphisms, particularly in the light of relatively scarce data regarding the MTHFR role in leukemia susceptibility in different populations.	0.047207275	2006	MTHFR	1	11794407	T	G
rs662	22976839	1728	NQO1	umls:C0023418	BeFree	The NQO1 rs1800566 (C609T), PON1 rs854560 (L55M), and PON1 rs662 (Q192R) polymorphisms modified risk depending on leukemia subtype (decreased in AML, increased and decreased in ALL, respectively), age strata, and variant genotype combinations.	0.023808397	2012	PON1	7	95308134	T	C
rs662	22976839	5444	PON1	umls:C0023418	BeFree	The NQO1 rs1800566 (C609T), PON1 rs854560 (L55M), and PON1 rs662 (Q192R) polymorphisms modified risk depending on leukemia subtype (decreased in AML, increased and decreased in ALL, respectively), age strata, and variant genotype combinations.	0.000271442	2012	PON1	7	95308134	T	C
rs703817	20438785	6778	STAT6	umls:C0023418	GAD	[Polymorphisms in innate immunity genes and risk of childhood leukemia.]	0.002367032	2010	STAT6	12	57096045	C	T
rs77375493	23432162	3717	JAK2	umls:C0023418	BeFree	Continued research into how miRNAs impact JAK2(V617F) clonal expansion, differential haematopoiesis among different MPNs, disease progression and leukaemia transformation will lead to a better understanding of the development of these disorders, their clinical manifestations, and their treatment.	0.144970109	2013	JAK2;INSL6	9	5073770	G	A,T
rs77375493	21712540	3717	JAK2	umls:C0023418	BeFree	Among the patients with myelofibrosis, those with ASXL1 lesions were not distinguished from their wild-type counterparts with regard to JAK2 V617F status, exposure to chemotherapy or evolution to leukemia.	0.144970109	2011	JAK2;INSL6	9	5073770	G	A,T
rs77375493	19691103	3717	JAK2	umls:C0023418	BeFree	JAK2 (V617F)-positive ET may evolve in few instances into JAK2-negative leukemia.	0.144970109	2009	JAK2;INSL6	9	5073770	G	A,T
rs77375493	21326037	4352	MPL	umls:C0023418	BeFree	Mutations in the thrombopoietin receptor gene (myeloproliferative leukemia, MPL) have been reported in patients with JAK2 V617F-negative chronic myeloproliferative disorders (MPDs).	0.005167327	2011	JAK2;INSL6	9	5073770	G	A,T
rs77375493	25479752	4297	KMT2A	umls:C0023418	BeFree	In mice, tamoxifen treatment blocked development of JAK2(V617F)-induced myeloproliferative neoplasm in vivo, induced apoptosis of human JAK2(V617F+) HSPCs in a xenograft model, and sensitized MLL-AF9(+) leukemias to chemotherapy.	0.240150617	2014	JAK2;INSL6	9	5073770	G	A,T
rs854560	22976839	5444	PON1	umls:C0023418	BeFree	The NQO1 rs1800566 (C609T), PON1 rs854560 (L55M), and PON1 rs662 (Q192R) polymorphisms modified risk depending on leukemia subtype (decreased in AML, increased and decreased in ALL, respectively), age strata, and variant genotype combinations.	0.000271442	2012	PON1	7	95316772	A	C,G,N,T
rs854560	22976839	1728	NQO1	umls:C0023418	BeFree	The NQO1 rs1800566 (C609T), PON1 rs854560 (L55M), and PON1 rs662 (Q192R) polymorphisms modified risk depending on leukemia subtype (decreased in AML, increased and decreased in ALL, respectively), age strata, and variant genotype combinations.	0.023808397	2012	PON1	7	95316772	A	C,G,N,T
rs861539	24304418	7517	XRCC3	umls:C0023418	BeFree	Association of XRCC3 Thr241Met polymorphism and leukemia risk: evidence from a meta-analysis.	0.007915422	2015	KLC1;XRCC3	14	103699416	G	A
rs861539	24197983	7517	XRCC3	umls:C0023418	BeFree	Comprehensive assessment of the association between DNA repair gene XRCC3 Thr241Met polymorphism and leukemia risk.	0.007915422	2013	KLC1;XRCC3	14	103699416	G	A
rs874881	17216583	23569	PADI4	umls:C0023418	BeFree	The functional haplotype of peptidylarginine deiminase IV (S55G, A82V and A112G) associated with susceptibility to rheumatoid arthritis dominates apoptosis of acute T leukemia Jurkat cells.	0.002995792	2007	PADI4	1	17334004	G	C,T

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:112)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	20930035	rs517483	C	T	rs517483	pha003091	2.69E-05	phs000221	phs000501	0.26	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
1	60876146	rs7529292	T	C	rs7529292	pha003091	8.76E-05	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
1	65580328	rs1572664	C	A	rs1572664	pha003091	2.25E-05	phs000221	phs000501	0.28	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
1	65580573	rs11208589	T	C	rs11208589	pha003091	6.06E-05	phs000221	phs000501	0.28	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
1	77818143	rs6672375	A	G	rs6672375	pha003091	4.20E-05	phs000221	phs000501	0.29	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
1	157811585	rs2281870	G	T	rs2281870	pha003091	5.14E-05	phs000221	phs000501	0.43	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
1	198564497	rs12144380	T	C	rs12144380	pha003091	7.75E-05	phs000221	phs000501	0.21	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
1	237420086	rs918241	C	A	rs918241	pha003091	4.52E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
1	237433239	rs4659491	T	C	rs4659491	pha003091	5.78E-06	phs000221	phs000501	0.22	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
2	34116688	rs773820	G	T	rs773820	pha003091	7.33E-05	phs000221	phs000501	0.27	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
2	41996612	rs4381822	A	G	rs4381822	pha003091	9.32E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
2	52017764	rs11686436	C	T	rs11686436	pha003091	1.06E-05	phs000221	phs000501	0.22	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
2	129981872	rs1251207	G	T	rs1251207	pha003091	5.44E-05	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
2	190146586	rs10207860	C	T	rs10207860	pha003091	5.50E-05	phs000221	phs000501	0.38	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
2	223758070	rs795887	C	T	rs795887	pha003091	5.69E-05	phs000221	phs000501	0.03	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
2	223766830	rs6722420	A	G	rs6722420	pha003091	7.81E-05	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
2	223808401	rs10755042	A	C	rs10755042	pha003091	9.35E-05	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
2	240574731	rs10165876	G	A	rs10165876	pha003091	3.62E-05	phs000221	phs000501	0.21	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
3	52825912	rs7549	C	A	rs7549	pha003091	8.76E-06	phs000221	phs000501	NA	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
3	55105390	rs358070	C	A	rs358070	pha003091	6.88E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
3	128594995	rs789214	A	G	rs789214	pha003091	9.59E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
3	171937014	rs6445047	T	C	rs6445047	pha003091	3.30E-05	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
3	171943473	rs7428410	C	T	rs7428410	pha003091	2.01E-05	phs000221	phs000501	0.25	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
3	171945349	rs13073573	C	T	rs13073573	pha003091	2.83E-05	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
3	171951160	rs4364195	A	G	rs4364195	pha003091	8.18E-05	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	7807834	rs1106248	T	C	rs1106248	pha003091	7.67E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	7831935	rs6446628	A	C	rs6446628	pha003091	4.49E-06	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	25476612	rs2875417	G	A	rs2875417	pha003091	7.58E-05	phs000221	phs000501	0.31	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	25531234	rs6448367	A	G	rs6448367	pha003091	8.17E-05	phs000221	phs000501	0.32	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	25536386	rs10018150	A	G	rs10018150	pha003091	5.00E-05	phs000221	phs000501	0.33	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	31335371	rs10517227	T	C	rs10517227	pha003091	9.37E-05	phs000221	phs000501	0.22	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	40368848	rs10021851	G	A	rs10021851	pha003091	2.88E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	60257454	rs7681982	T	C	rs7681982	pha003091	1.08E-05	phs000221	phs000501	0.22	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	60283466	rs1511404	A	C	rs1511404	pha003091	1.18E-05	phs000221	phs000501	0.22	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	60306500	rs2048462	T	C	rs2048462	pha003091	9.57E-06	phs000221	phs000501	0.22	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	60314905	rs6826593	T	C	rs6826593	pha003091	1.26E-05	phs000221	phs000501	0.21	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	60442490	rs17290779	T	C	rs17290779	pha003091	9.82E-05	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	157104958	rs12508572	T	C	rs12508572	pha003091	9.79E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
4	170232880	rs13128807	G	A	rs13128807	pha003091	7.30E-05	phs000221	phs000501	0.21	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
5	11190339	rs32275	T	C	rs32275	pha003091	3.26E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
5	101638381	rs1982418	G	A	rs1982418	pha003091	6.94E-05	phs000221	phs000501	0.21	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
5	101669015	rs12655961	G	A	rs12655961	pha003091	9.70E-06	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
5	101843759	rs953280	T	C	rs953280	pha003091	3.45E-05	phs000221	phs000501	0.04	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
5	102003138	rs2671569	A	G	rs2671569	pha003091	9.95E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
5	176601031	rs1546363	C	T	rs1546363	pha003091	3.51E-05	phs000221	phs000501	0.26	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
6	8273873	rs591705	G	A	rs591705	pha003091	1.42E-05	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
6	8278455	rs663716	T	C	rs663716	pha003091	1.58E-05	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
6	39174612	rs10947788	C	T	rs10947788	pha003091	5.30E-05	phs000221	phs000501	0.21	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
6	45928400	rs1555214	C	T	rs1555214	pha003091	1.32E-05	phs000221	phs000501	0.22	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
6	110250208	rs9374140	T	C	rs9374140	pha003091	2.47E-05	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
6	145162225	rs1111808	A	G	rs1111808	pha003091	1.88E-05	phs000221	phs000501	0.04	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
6	145162512	rs1111807	T	G	rs1111807	pha003091	1.98E-05	phs000221	phs000501	0.34	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
6	145169607	rs6903007	T	C	rs6903007	pha003091	8.65E-06	phs000221	phs000501	0.35	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
6	145184504	rs4321838	A	C	rs4321838	pha003091	7.15E-06	phs000221	phs000501	0.34	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
7	73724962	rs229877	C	T	rs229877	pha003091	8.18E-05	phs000221	phs000501	0.22	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
7	73760704	rs523434	G	A	rs523434	pha003091	1.42E-05	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
7	90840353	rs11970859	G	A	rs11970859	pha003091	1.70E-05	phs000221	phs000501	0.38	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
7	134471211	rs6467557	T	G	rs6467557	pha003091	7.44E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
7	138380477	rs6944016	G	A	rs6944016	pha003091	1.99E-05	phs000221	phs000501	0.43	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
8	76028740	rs1378615	C	T	rs1378615	pha003091	4.43E-05	phs000221	phs000501	0.25	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
8	101268237	rs1660350	G	A	rs1660350	pha003091	1.82E-05	phs000221	phs000501	0.21	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
8	125571747	rs6470250	T	C	rs6470250	pha003091	9.72E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
8	139975998	rs6577977	C	A	rs6577977	pha003091	6.22E-05	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
9	10311825	rs635858	C	T	rs635858	pha003091	1.41E-05	phs000221	phs000501	0.27	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
9	10314941	rs680760	T	C	rs680760	pha003091	9.49E-06	phs000221	phs000501	0.27	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
9	10336364	rs10114902	T	C	rs10114902	pha003091	7.59E-05	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
9	72429750	rs7863087	T	C	rs7863087	pha003091	4.22E-05	phs000221	phs000501	0.39	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
9	77535027	rs12379179	T	C	rs12379179	pha003091	3.90E-05	phs000221	phs000501	0.29	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
9	127710312	rs13299805	T	C	rs13299805	pha003091	3.73E-05	phs000221	phs000501	0.43	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
10	1923792	rs7073281	G	T	rs7073281	pha003091	5.51E-05	phs000221	phs000501	0.28	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
10	72424452	rs17528058	C	T	rs17528058	pha003091	5.97E-05	phs000221	phs000501	0.22	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
10	97269933	rs12776562	C	A	rs12776562	pha003091	7.98E-06	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
10	97284081	rs1326934	C	T	rs1326934	pha003091	6.21E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
10	97289992	rs11188346	G	A	rs11188346	pha003091	2.83E-05	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
10	97294813	rs10882611	G	A	rs10882611	pha003091	1.31E-05	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
10	117844044	rs7087152	C	T	rs7087152	pha003091	6.09E-05	phs000221	phs000501	0.25	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
11	11505004	rs12293824	G	A	rs12293824	pha003091	6.67E-05	phs000221	phs000501	0.34	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
11	21436232	rs11026076	T	C	rs11026076	pha003091	2.09E-06	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
11	21437692	rs7943922	T	G	rs7943922	pha003091	3.07E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
11	21522529	rs10219188	T	G	rs10219188	pha003091	3.85E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
11	44363600	rs4755813	C	T	rs4755813	pha003091	5.07E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
11	123038840	rs10790558	A	G	rs57232670	pha003091	9.15E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
12	22976813	rs12581238	T	C	rs12581238	pha003091	3.85E-05	phs000221	phs000501	0.35	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
12	50335086	rs296742	T	C	rs296742	pha003091	8.92E-05	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
12	99135638	rs4762507	C	T	rs4762507	pha003091	1.27E-05	phs000221	phs000501	0.27	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
12	115206320	rs1566643	A	G	rs1566643	pha003091	4.16E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
12	115453154	rs10850428	C	T	rs10850428	pha003091	8.19E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
13	23827815	rs7995077	G	A	rs7995077	pha003091	6.14E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
13	23855056	rs11617228	T	C	rs11617228	pha003091	5.42E-05	phs000221	phs000501	0.22	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
13	23864250	rs1887756	G	T	rs1887756	pha003091	1.95E-05	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
13	84214404	rs7322996	T	C	rs7322996	pha003091	5.24E-05	phs000221	phs000501	0.24	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
13	94490519	rs1330458	C	T	rs1330458	pha003091	7.94E-05	phs000221	phs000501	0.37	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
14	58452939	rs808208	G	A	rs808208	pha003091	8.08E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
14	59180300	rs8022761	T	C	rs8022761	pha003091	3.35E-05	phs000221	phs000501	0.26	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
14	65336050	rs2828	T	G	rs2828	pha003091	9.98E-05	phs000221	phs000501	0.21	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
15	78439120	rs2028548	C	T	rs2028548	pha003091	5.75E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
16	7420486	rs7206595	G	A	rs7206595	pha003091	4.26E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
16	7433110	rs4627375	A	G	rs4627375	pha003091	6.66E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
16	24462555	rs9930580	T	C	rs9930580	pha003091	1.30E-05	phs000221	phs000501	0.45	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
16	64221018	rs9931309	C	A	rs9931309	pha003091	1.50E-05	phs000221	phs000501	0.26	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
17	8595094	rs7213402	C	T	rs7213402	pha003091	2.09E-05	phs000221	phs000501	0.21	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
17	26106675	rs4795067	A	G	rs4795067	pha003091	9.94E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
17	32159519	rs2881782	A	C	rs2881782	pha003091	9.96E-05	phs000221	phs000501	0.19	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
17	63099682	rs1808918	C	T	rs1808918	pha003091	3.35E-05	phs000221	phs000501	0.2	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
18	4025719	rs1442385	G	A	rs1442385	pha003091	2.91E-05	phs000221	phs000501	0.23	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
18	11759432	rs9947295	C	T	rs9947295	pha003091	6.25E-05	phs000221	phs000501	0.32	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
19	49361255	rs17206700	T	C	rs17206700	pha003091	1.44E-05	phs000221	phs000501	0.27	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
19	49362992	rs17272673	C	A	rs17272673	pha003091	1.55E-05	phs000221	phs000501	0.27	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
20	17479730	rs6111549	T	C	rs6111549	pha003091	2.20E-05	phs000221	phs000501	0.21	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
21	16848564	rs2823295	T	C	rs2823295	pha003091	1.42E-05	phs000221	phs000501	0.27	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
21	31050817	rs363512	G	A	rs363512	pha003091	2.15E-05	phs000221	phs000501	0.39	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia
22	48178105	rs9627141	A	G	rs9627141	pha003091	6.51E-05	phs000221	phs000501	0.31	NA	NA	ALL(0)	ALL(0)	Leukocyte Counts	HPOID:0001909	Leukemia	DOID:1240	DOID:0060058	DOID:1287	leukemia	lymphoma	cardiovascular system disease	NA	NA	NA	NA	Lymphoma	Leukemia

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:32)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0023418	amlodipine	D017311	88150-42-9	leukemia	MESH:D007938	therapeutic	16684125
C0023418	amsacrine	D000677	-	leukemia	MESH:D007938	therapeutic	3681383
C0023418	arsenic trioxide	C006632	1327-53-3	leukemia	MESH:D007938	therapeutic	15070760
C0023418	azacitidine	D001374	320-67-2	leukemia	MESH:D007938	marker/mechanism	2408741
C0023418	azacitidine	D001374	320-67-2	leukemia	MESH:D007938	therapeutic	19148494
C0023418	bortezomib	D000069286	-	leukemia	MESH:D007938	therapeutic	15039284
C0023418	carmustine	D002330	154-93-8	leukemia	MESH:D007938	therapeutic	11960597
C0023418	chlorambucil	D002699	305-03-3	leukemia	MESH:D007938	therapeutic	118440
C0023418	chloramphenicol	D002701	56-75-7	leukemia	MESH:D007938	marker/mechanism	1211407
C0023418	chloramphenicol	D002701	56-75-7	leukemia	MESH:D007938	therapeutic	8834551
C0023418	cyclophosphamide	D003520	50-18-0	leukemia	MESH:D007938	marker/mechanism	572348
C0023418	cyclophosphamide	D003520	50-18-0	leukemia	MESH:D007938	therapeutic	10602166
C0023418	dasatinib	D000069439	-	leukemia	MESH:D007938	therapeutic	28243904
C0023418	decitabine	C014347	2353-33-5	leukemia	MESH:D007938	therapeutic	18980019
C0023418	cisplatin	D002945	15663-27-1	leukemia	MESH:D007938	marker/mechanism	24798381
C0023418	calcitriol	D002117	32222-06-3	leukemia	MESH:D007938	therapeutic	10470102
C0023418	hydroxyurea	D006918	127-07-1	leukemia	MESH:D007938	marker/mechanism	11317962
C0023418	hydroxyurea	D006918	127-07-1	leukemia	MESH:D007938	therapeutic	17686055
C0023418	ifosfamide	D007069	3778-73-2	leukemia	MESH:D007938	marker/mechanism	7596151
C0023418	imatinib mesylate	D000068877	-	leukemia	MESH:D007938	therapeutic	24240679
C0023418	lindane	D001556	58-89-9	leukemia	MESH:D007938	marker/mechanism	17096337
C0023418	methotrexate	D008727	1959/5/2	leukemia	MESH:D007938	therapeutic	10458822
C0023418	mitoxantrone	D008942	65271-80-9	leukemia	MESH:D007938	marker/mechanism	15623667
C0023418	mitoxantrone	D008942	65271-80-9	leukemia	MESH:D007938	therapeutic	3481363
C0023418	nelfinavir	D019888	159989-64-7	leukemia	MESH:D007938	therapeutic	20105315
C0023418	paclitaxel	D017239	-	leukemia	MESH:D007938	therapeutic	7904060
C0023418	paricalcitol	C084656	-	leukemia	MESH:D007938	therapeutic	12618899
C0023418	sorafenib	C471405	-	leukemia	MESH:D007938	therapeutic	17205056
C0023418	temozolomide	C047246	85622-93-1	leukemia	MESH:D007938	therapeutic	15360003
C0023418	tretinoin	D014212	302-79-4	leukemia	MESH:D007938	therapeutic	17143497
C0023418	vincristine	D014750	-	leukemia	MESH:D007938	therapeutic	3875694
C0023418	vindesine	D014751	53643-48-4	leukemia	MESH:D007938	therapeutic	6268296

FDA approved drug and dosage information(Total Drugs:10)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D007938	calcijex	calcitriol	0.001MG/ML Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	INJECTABLE;INJECTION	Discontinued	None	Yes	No
MESH:D007938	temodar	temozolomide	5MG	CAPSULE;ORAL	Prescription	AB	Yes	No
MESH:D007938	temodar	temozolomide	100MG/VIAL	POWDER;INTRAVENOUS	Prescription	None	Yes	Yes
MESH:D007938	zemplar	paricalcitol	0.005MG/ML (0.005MG/ML)	SOLUTION;INTRAVENOUS	Prescription	AP	Yes	Yes
MESH:D007938	zemplar	paricalcitol	1MCG	CAPSULE;ORAL	Prescription	AB	No	No
MESH:D007938	zemplar	paricalcitol	0.005MG/ML (0.005MG/ML)	SOLUTION;INTRAVENOUS	Prescription	AP	Yes	Yes
MESH:D007938	zemplar	paricalcitol	1MCG	CAPSULE;ORAL	Prescription	AB	No	No
MESH:D007938	gleevec	imatinib mesylate	EQ 50MG BASE Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	CAPSULE;ORAL	Discontinued	None	Yes	No
MESH:D007938	gleevec	imatinib mesylate	EQ 100MG BASE	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D007938	velcade	bortezomib	3.5MG/VIAL	INJECTABLE;INTRAVENOUS, SUBCUTANEOUS	Prescription	None	Yes	Yes

FDA labeling changes(Total Drugs:10)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D007938	11/16/2001	calcijex	calcitriol	Management of hypocalcemia in patients undergoing chronic renal dialysis	The safety and effectiveness of calcitriol was examined in a double-blind placebo-controlled trial of 35 pediatric patients (13-18 years of age) with end-stage renal disease and on dialysis. The primary efficacy endpoint favored the calcitriol-treated versus the placebo-treated patients Transient hypercalcemia was seen in 1 of 16 calcitriol-treated patients; 6 of 16 (38%) calcitriol-treated patients and 2 of 19 (11%) placebo-treated patients had Ca x P >75	Labeling	B	-	-	-	Abbott	02/16/2001	FALSE'
MESH:D007938	11/3/2003	temodar	temozolomide	Recurrent CNS tumors	Temozolomide effectiveness in children has not been demonstrated New data from 2 open-label Phase 2 studies in pediatric patients 3-18 years of age. In one study there were 29 patients with recurrent brain stem glioma and 34 patients with recurrent high grade astrocyoma. In a second study there were 122 patients enrolled with various types of tumors; 113 CNS tumors and 9 non-CNS tumors. The temozolomide toxicity profile in children is similar to adults	Labeling	B	-	-	-	Schering	11/20/2002	FALSE'
MESH:D007938	11/3/2003	temodar	temozolomide	Recurrent CNS tumors	Temozolomide effectiveness in children has not been demonstrated New data from 2 open-label Phase 2 studies in pediatric patients 3-18 years of age. In one study there were 29 patients with recurrent brain stem glioma and 34 patients with recurrent high grade astrocyoma. In a second study there were 122 patients enrolled with various types of tumors; 113 CNS tumors and 9 non-CNS tumors. The temozolomide toxicity profile in children is similar to adults	Labeling	B	-	-	-	Schering	11/20/2002	FALSE'
MESH:D007938	03/31/2004	zemplar	paricalcitol	Secondary hyperparathyroidism associated with end stage renal disease	Safety and effectiveness were examined in a 12 week randomized, double-blind, placebo-controlled study of 29 pediatric patients aged 5-19 years old with end stage renal disease on hemodialysis; information Primary efficacy analysis revealed 9 of 15 patients in Zemplar group had 2 consecutive 30 % decreases from baseline intact PTH compared with 3 of 14 patients in placebo group No patients in either group developed hypercalcemia (defined as at least one calcium value >11.2 mg/dL) during study	Labeling	B	-	-	-	Abbott	8/12/2003	FALSE'
MESH:D007938	03/31/2004	zemplar	paricalcitol	Secondary hyperparathyroidism associated with end stage renal disease	Safety and effectiveness were examined in a 12 week randomized, double-blind, placebo-controlled study of 29 pediatric patients aged 5-19 years old with end stage renal disease on hemodialysis; information Primary efficacy analysis revealed 9 of 15 patients in Zemplar group had 2 consecutive 30 % decreases from baseline intact PTH compared with 3 of 14 patients in placebo group No patients in either group developed hypercalcemia (defined as at least one calcium value >11.2 mg/dL) during study	Labeling	B	-	-	-	Abbott	8/12/2003	FALSE'
MESH:D007938	10/18/2016	zemplar	paricalcitol	Secondary hyperparathyroidism associated with chronic kidney disease (CKD) Stage 3, 4 and 5 in pediatric patients 10 to 16 years	Safety and effectiveness have been established in pediatric patients 10 to 16 years of age. Use in this age group is supported by evidence from adequate and well controlled studies in adults with CKD, a 12-week double-blind placebo-controlled randomized multicenter study in 36 pediatric patients 10 to 16 years of age with CKD Stages 3 and 4, and safety data from a 12-week open-label single-arm multicenter study in 13 pediatric patients 10 to 16 years of age with CKD Stage 5 receiving peritoneal dialysis or hemodialysis. Safety and effectiveness in pediatric patients under the age of 10 years have not been established. Adverse reactions were similar to those reported in adults. Information on dosing, pharmacokinetic parameters, and clinical trial. Postmarketing study	-	-	P	-	-	AbbVie Inc.	-	FALSE
MESH:D007938	10/18/2016	zemplar	paricalcitol	Secondary hyperparathyroidism associated with chronic kidney disease (CKD) Stage 3, 4 and 5 in pediatric patients 10 to 16 years	Safety and effectiveness have been established in pediatric patients 10 to 16 years of age. Use in this age group is supported by evidence from adequate and well controlled studies in adults with CKD, a 12-week double-blind placebo-controlled randomized multicenter study in 36 pediatric patients 10 to 16 years of age with CKD Stages 3 and 4, and safety data from a 12-week open-label single-arm multicenter study in 13 pediatric patients 10 to 16 years of age with CKD Stage 5 receiving peritoneal dialysis or hemodialysis. Safety and effectiveness in pediatric patients under the age of 10 years have not been established. Adverse reactions were similar to those reported in adults. Information on dosing, pharmacokinetic parameters, and clinical trial. Postmarketing study	-	-	P	-	-	AbbVie Inc.	-	FALSE
MESH:D007938	09/27/2006	gleevec	imatinib mesylate	Treatment of newly diagnosed pediatric patients with Philadelphia chromosome positive (Ph+) chronic myeloid leukemia (CML) in chronic phase	Extended age range for the treatment of newly diagnosed CML down to pediatric patients There are no data in children < 2 years of age Follow-up in children with newly diagnosed Ph+ chronic phase CML is limited Information on hematologic toxicities, AE profile, clinical studies and dosing guidelines new for newly diagnosed pediatric patients	Labeling	-	-	B, P	-	Novartis	9/6/2006	FALSE'
MESH:D007938	09/27/2006	gleevec	imatinib mesylate	Treatment of newly diagnosed pediatric patients with Philadelphia chromosome positive (Ph+) chronic myeloid leukemia (CML) in chronic phase	Extended age range for the treatment of newly diagnosed CML down to pediatric patients There are no data in children < 2 years of age Follow-up in children with newly diagnosed Ph+ chronic phase CML is limited Information on hematologic toxicities, AE profile, clinical studies and dosing guidelines new for newly diagnosed pediatric patients	Labeling	-	-	B, P	-	Novartis	9/6/2006	FALSE'
MESH:D007938	09/14/2015	velcade	bortezomib	Relapsed Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma (LL)	Effectiveness in pediatric patients with relapsed pre-B ALL has not been established. The activity and safety of Velcade in combination with intensive reinduction chemotherapy was evaluated in pediatric and young adult patients with lymphoid malignancies. There were 140 patients with ALL or LL enrolled and evaluated for safety. No new safety concerns were observed	Labeling	B	-	-	-	Millennium Pharmaceuticals, Inc.	-	FALSE