PedAM

Pediatric Disease Annotations & Medicines


	leprosy

Disease ID	351
Disease	leprosy
Definition	A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
Synonym	[x]leprosy, unspecified [x]leprosy, unspecified (disorder) disease, hansen disease, hansen's hansen dis hansen disease hansen's disease hansens dis hansens disease infection due to mycobacterium leprae leprosies leprosy (disorder) leprosy [disease/finding] leprosy nos leprosy nos (disorder) leprosy, nos leprosy, unspecified mycobacterium leprae infection
Orphanet	ORPHANET:548
DOID	DOID:1024
ICD10	ICD10CM:A30.9
UMLS	C0023343
MeSH	D007918
SNOMED-CT	SNOMEDCT_US_2016_09_01:81004002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:59) C0442874 \| neuropathy \| 15 C0041296 \| tuberculosis \| 10 C0003864 \| arthritis \| 4 C0019158 \| hepatitis \| 4 C0152226 \| lagophthalmos \| 3 C0027813 \| neuritis \| 3 C0040053 \| thrombosis \| 2 C0008582 \| chromoblastomycosis \| 2 C0042900 \| vitiligo \| 2 C0154743 \| ulnar neuropathy \| 2 C0023351 \| tuberculoid leprosy \| 1 C0042109 \| urticaria \| 1 C0019163 \| hepatitis b \| 1 C0031090 \| periodontal disease \| 1 C0042164 \| uveitis \| 1 C0017658 \| glomerulonephritis \| 1 C0040997 \| trigeminal neuralgia \| 1 C0029134 \| optic neuritis \| 1 C0042769 \| virus infection \| 1 C0022081 \| iritis \| 1 C0019196 \| hepatitis c \| 1 C1510429 \| entrapment neuropathy \| 1 C0003873 \| rheumatoid arthritis \| 1 C0020757 \| ichthyosis \| 1 C0206706 \| verrucous carcinoma \| 1 C0003467 \| anxiety \| 1 C0162429 \| malnutrition \| 1 C0007137 \| squamous cell carcinoma \| 1 C0040034 \| thrombocytopenia \| 1 C0018081 \| gonorrhea \| 1 C0012546 \| diphtheria \| 1 C0003864 \| inflammatory arthritis \| 1 C0019655 \| histoplasmosis \| 1 C0035459 \| atrophic rhinitis \| 1 C0242292 \| mccune-albright syndrome \| 1 C0004030 \| aspergillosis \| 1 C0023281 \| leishmaniasis \| 1 C0241910 \| autoimmune hepatitis \| 1 C0035078 \| renal failure \| 1 C0004936 \| mental disorders \| 1 C0011570 \| depression \| 1 C0041309 \| cutaneous tuberculosis \| 1 C0033975 \| psychosis \| 1 C0409974 \| lupus erythematosus \| 1 C0085113 \| neurofibromatosis \| 1 C0042164 \| intraocular inflammation \| 1 C0029443 \| osteomyelitis \| 1 C0011849 \| diabetes mellitus \| 1 C0035455 \| rhinitis \| 1 C0242292 \| albright syndrome \| 1 C0042165 \| anterior uveitis \| 1 C0041327 \| pulmonary tuberculosis \| 1 C0314719 \| dry eye \| 1 C0015464 \| facial nerve palsy \| 1 C0004623 \| bacterial infection \| 1 C0403416 \| crescentic glomerulonephritis \| 1 C0033860 \| psoriasis \| 1 C0014804 \| erythromelalgia \| 1 C0022658 \| kidney disease \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:21) TLR1 \| 7096 \| CTD_human PARK2 \| 5071 \| CTD_human IL23R \| 149233 \| CTD_human SLC11A1 \| 6556 \| CTD_human LACC1 \| 144811 \| GWASCAT ADGB \| 79747 \| GWASCAT TLR2 \| 7097 \| CTD_human LTA \| 4049 \| CTD_human SLC2A13 \| 114134 \| GWASCAT C1orf141 \| 400757 \| GWASCAT CCDC88B \| 283234 \| CTD_human;GWASCAT RAB32 \| 10981 \| CTD_human TNFSF15 \| 9966 \| GWASCAT BATF3 \| 55509 \| CTD_human;GWASCAT IL1RL1 \| 9173 \| GWASCAT COX4I1 \| 1327 \| GWASCAT PACRG \| 135138 \| CTD_human RIPK2 \| 8767 \| GWASCAT CDH18 \| 1016 \| GWASCAT SNX20 \| 124460 \| GWASCAT SIGLEC5 \| 8778 \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:79) 259173 \| ALS2CL \| infer 56244 \| BTNL2 \| infer 400757 \| C1orf141 \| infer 29113 \| C6orf15 \| infer 80099 \| C7orf69 \| infer 160857 \| CCDC122 \| infer 30835 \| CD209 \| infer 55561 \| CDC42BPG \| infer 1540 \| CYLD \| infer 375061 \| FAM89A \| infer 2220 \| FCN2 \| infer 54331 \| GNG2 \| infer 3105 \| HLA-A \| infer 3106 \| HLA-B \| infer 3107 \| HLA-C \| infer 3112 \| HLA-DOB \| infer 3117 \| HLA-DQA1 \| infer 3119 \| HLA-DQB1 \| infer 3120 \| HLA-DQB2 \| infer 3122 \| HLA-DRA \| infer 3123 \| HLA-DRB1 \| infer 3127 \| HLA-DRB5 \| infer 3128 \| HLA-DRB6 \| infer 100131609 \| HNRNPA1P2 \| infer 3458 \| IFNG \| infer 3459 \| IFNGR1 \| infer 3586 \| IL10 \| infer 3594 \| IL12RB1 \| infer 3595 \| IL12RB2 \| infer 3558 \| IL2 \| infer 3569 \| IL6 \| infer 3802 \| KIR2DL1 \| infer 3803 \| KIR2DL2 \| infer 3804 \| KIR2DL3 \| infer 3805 \| KIR2DL4 \| infer 57292 \| KIR2DL5A \| infer 554300 \| KIR2DP1 \| infer 3806 \| KIR2DS1 \| infer 100132285 \| KIR2DS2 \| infer 3808 \| KIR2DS3 \| infer 3809 \| KIR2DS4 \| infer 3810 \| KIR2DS5 \| infer 3811 \| KIR3DL1 \| infer 3812 \| KIR3DL2 \| infer 115653 \| KIR3DL3 \| infer 548594 \| KIR3DP1 \| infer 3813 \| KIR3DS1 \| infer 391827 \| KRT18P16 \| infer 3908 \| LAMA2 \| infer 4049 \| LTA \| infer 5871 \| MAP4K2 \| infer 4153 \| MBL2 \| infer 4221 \| MEN1 \| infer 100507436 \| MICA \| infer 4277 \| MICB \| infer 10392 \| NOD1 \| infer 64127 \| NOD2 \| infer 135138 \| PACRG \| infer 5071 \| PARK2 \| infer 168507 \| PKD1L1 \| infer 5588 \| PRKCQ \| infer 170679 \| PSORS1C1 \| infer 26191 \| PTPN22 \| infer 8767 \| RIPK2 \| infer 100271332 \| RPL36AP21 \| infer 8986 \| RPS6KA4 \| infer 6456 \| SH3GL2 \| infer 6556 \| SLC11A1 \| infer 124460 \| SNX20 \| infer 6891 \| TAP2 \| infer 7040 \| TGFB1 \| infer 7096 \| TLR1 \| infer 7097 \| TLR2 \| infer 7099 \| TLR4 \| infer 7124 \| TNF \| infer 9966 \| TNFSF15 \| infer 57176 \| VARS2 \| infer 7421 \| VDR \| infer 387122 \| WASF5P \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:257) 6362 \| CCL18 \| DISEASES 3385 \| ICAM3 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 4804 \| NGFR \| DISEASES 350 \| APOH \| DISEASES 3002 \| GZMB \| DISEASES 4313 \| MMP2 \| DISEASES 11151 \| CORO1A \| DISEASES 8767 \| RIPK2 \| DISEASES 8797 \| TNFRSF10A \| DISEASES 7040 \| TGFB1 \| DISEASES 973 \| CD79A \| DISEASES 10392 \| NOD1 \| DISEASES 6348 \| CCL3 \| DISEASES 6347 \| CCL2 \| DISEASES 8456 \| FOXN1 \| DISEASES 3558 \| IL2 \| DISEASES 969 \| CD69 \| DISEASES 9761 \| MLEC \| DISEASES 3458 \| IFNG \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 51185 \| CRBN \| DISEASES 6556 \| SLC11A1 \| DISEASES 3336 \| HSPE1 \| DISEASES 23169 \| SLC35D1 \| DISEASES 6402 \| SELL \| DISEASES 7141 \| TNP1 \| DISEASES 4360 \| MRC1 \| DISEASES 1959 \| EGR2 \| DISEASES 55509 \| BATF3 \| DISEASES 22863 \| ATG14 \| DISEASES 7429 \| VIL1 \| DISEASES 968 \| CD68 \| DISEASES 6351 \| CCL4 \| DISEASES 11027 \| LILRA2 \| DISEASES 4298 \| MLLT1 \| DISEASES 3958 \| LGALS3 \| DISEASES 1401 \| CRP \| DISEASES 9645 \| MICAL2 \| DISEASES 3568 \| IL5RA \| DISEASES 8638 \| OASL \| DISEASES 80896 \| NPL \| DISEASES 3569 \| IL6 \| DISEASES 27348 \| TOR1B \| DISEASES 7097 \| TLR2 \| DISEASES 4069 \| LYZ \| DISEASES 2581 \| GALC \| DISEASES 27190 \| IL17B \| DISEASES 5934 \| RBL2 \| DISEASES 3595 \| IL12RB2 \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 10578 \| GNLY \| DISEASES 941 \| CD80 \| DISEASES 80725 \| SRCIN1 \| DISEASES 3383 \| ICAM1 \| DISEASES 7535 \| ZAP70 \| DISEASES 7879 \| RAB7A \| DISEASES 6717 \| SRI \| DISEASES 79109 \| MAPKAP1 \| DISEASES 3700 \| ITIH4 \| DISEASES 4060 \| LUM \| DISEASES 3687 \| ITGAX \| DISEASES 3394 \| IRF8 \| DISEASES 8547 \| FCN3 \| DISEASES 148327 \| CREB3L4 \| DISEASES 3930 \| LBR \| DISEASES 5868 \| RAB5A \| DISEASES 55435 \| AP1AR \| DISEASES 3578 \| IL9 \| DISEASES 123 \| PLIN2 \| DISEASES 3606 \| IL18 \| DISEASES 3948 \| LDHC \| DISEASES 7345 \| UCHL1 \| DISEASES 3588 \| IL10RB \| DISEASES 1636 \| ACE \| DISEASES 2220 \| FCN2 \| DISEASES 115 \| ADCY9 \| DISEASES 213 \| ALB \| DISEASES 57159 \| TRIM54 \| DISEASES 3600 \| IL15 \| DISEASES 134147 \| CMBL \| DISEASES 94234 \| FOXQ1 \| DISEASES 1437 \| CSF2 \| DISEASES 115825 \| WDFY2 \| DISEASES 120892 \| LRRK2 \| DISEASES 64127 \| NOD2 \| DISEASES 94235 \| GNG8 \| DISEASES 1642 \| DDB1 \| DISEASES 116071 \| BATF2 \| DISEASES 6356 \| CCL11 \| DISEASES 3308 \| HSPA4 \| DISEASES 3688 \| ITGB1 \| DISEASES 1493 \| CTLA4 \| DISEASES 3596 \| IL13 \| DISEASES 3627 \| CXCL10 \| DISEASES 8436 \| SDPR \| DISEASES 203100 \| HTRA4 \| DISEASES 81851 \| KRTAP1-1 \| DISEASES 6504 \| SLAMF1 \| DISEASES 2147 \| F2 \| DISEASES 344561 \| GPR148 \| DISEASES 1657 \| DMXL1 \| DISEASES 7368 \| UGT8 \| DISEASES 1605 \| DAG1 \| DISEASES 8557 \| TCAP \| DISEASES 3952 \| LEP \| DISEASES 10713 \| USP39 \| DISEASES 54472 \| TOLLIP \| DISEASES 30835 \| CD209 \| DISEASES 8225 \| GTPBP6 \| DISEASES 63973 \| NEUROG2 \| DISEASES 144811 \| LACC1 \| DISEASES 1960 \| EGR3 \| DISEASES 6863 \| TAC1 \| DISEASES 149233 \| IL23R \| DISEASES 2253 \| FGF8 \| DISEASES 9235 \| IL32 \| DISEASES 9033 \| PKD2L1 \| DISEASES 55486 \| PARL \| DISEASES 10250 \| SRRM1 \| DISEASES 3052 \| HCCS \| DISEASES 4843 \| NOS2 \| DISEASES 3563 \| IL3RA \| DISEASES 706 \| TSPO \| DISEASES 340061 \| TMEM173 \| DISEASES 25834 \| MGAT4C \| DISEASES 6401 \| SELE \| DISEASES 942 \| CD86 \| DISEASES 340075 \| ARSI \| DISEASES 2774 \| GNAL \| DISEASES 112744 \| IL17F \| DISEASES 3932 \| LCK \| DISEASES 135138 \| PACRG \| DISEASES 3266 \| ERAS \| DISEASES 3117 \| HLA-DQA1 \| DISEASES 3329 \| HSPD1 \| DISEASES 3804 \| KIR2DL3 \| DISEASES 6633 \| SNRPD2 \| DISEASES 81551 \| STMN4 \| DISEASES 4077 \| NBR1 \| DISEASES 3605 \| IL17A \| DISEASES 8328 \| GFI1B \| DISEASES 1811 \| SLC26A3 \| DISEASES 390792 \| KRT39 \| DISEASES 5265 \| SERPINA1 \| DISEASES 3240 \| HP \| DISEASES 91137 \| SLC25A46 \| DISEASES 6288 \| SAA1 \| DISEASES 399888 \| FAM180B \| DISEASES 283234 \| CCDC88B \| DISEASES 246778 \| IL27 \| DISEASES 26136 \| TES \| DISEASES 6775 \| STAT4 \| DISEASES 7048 \| TGFBR2 \| DISEASES 9332 \| CD163 \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 8532 \| CPZ \| DISEASES 7096 \| TLR1 \| DISEASES 5071 \| PARK2 \| DISEASES 3664 \| IRF6 \| DISEASES 5362 \| PLXNA2 \| DISEASES 1378 \| CR1 \| DISEASES 6993 \| DYNLT1 \| DISEASES 25802 \| LMOD1 \| DISEASES 10981 \| RAB32 \| DISEASES 3459 \| IFNGR1 \| DISEASES 1805 \| DPT \| DISEASES 910 \| CD1B \| DISEASES 912 \| CD1D \| DISEASES 441168 \| FAM26F \| DISEASES 6283 \| S100A12 \| DISEASES 6280 \| S100A9 \| DISEASES 55278 \| QRSL1 \| DISEASES 2209 \| FCGR1A \| DISEASES 914 \| CD2 \| DISEASES 4803 \| NGF \| DISEASES 2316 \| FLNA \| DISEASES 2773 \| GNAI3 \| DISEASES 959 \| CD40LG \| DISEASES 680 \| BRS3 \| DISEASES 400757 \| C1orf141 \| DISEASES 6342 \| SCP2 \| DISEASES 3597 \| IL13RA1 \| DISEASES 55661 \| DDX27 \| DISEASES 2219 \| FCN1 \| DISEASES 2491 \| CENPI \| DISEASES 129685 \| TAF8 \| DISEASES 5292 \| PIM1 \| DISEASES 4153 \| MBL2 \| DISEASES 7099 \| TLR4 \| DISEASES 9966 \| TNFSF15 \| DISEASES 91544 \| UBXN11 \| DISEASES 58476 \| TP53INP2 \| DISEASES 63940 \| GPSM3 \| DISEASES 8451 \| CUL4A \| DISEASES 4814 \| NINJ1 \| DISEASES 6392 \| SDHD \| DISEASES 7709 \| ZBTB17 \| DISEASES 4795 \| NFKBIL1 \| DISEASES 50943 \| FOXP3 \| DISEASES 100507436 \| MICA \| DISEASES 7133 \| TNFRSF1B \| DISEASES 3105 \| HLA-A \| DISEASES 10529 \| NEBL \| DISEASES 3604 \| TNFRSF9 \| DISEASES 8718 \| TNFRSF25 \| DISEASES 9308 \| CD83 \| DISEASES 9912 \| ARHGAP44 \| DISEASES 3559 \| IL2RA \| DISEASES 57486 \| NLN \| DISEASES 438 \| ASMT \| DISEASES 10333 \| TLR6 \| DISEASES 55276 \| PGM2 \| DISEASES 51520 \| LARS \| DISEASES 50801 \| KCNK4 \| DISEASES 4891 \| SLC11A2 \| DISEASES 4773 \| NFATC2 \| DISEASES 79168 \| LILRA6 \| DISEASES 79747 \| ADGB \| DISEASES 594857 \| NPS \| DISEASES 2687 \| GGT5 \| DISEASES 56099 \| PCDHGB7 \| DISEASES 3119 \| HLA-DQB1 \| DISEASES 1439 \| CSF2RB \| DISEASES 7018 \| TF \| DISEASES 50489 \| CD207 \| DISEASES 29072 \| SETD2 \| DISEASES 340351 \| AGBL3 \| DISEASES 3120 \| HLA-DQB2 \| DISEASES 25801 \| GCA \| DISEASES 1029 \| CDKN2A \| DISEASES 7124 \| TNF \| DISEASES 3106 \| HLA-B \| DISEASES 3594 \| IL12RB1 \| DISEASES 4049 \| LTA \| DISEASES 4152 \| MBD1 \| DISEASES 388372 \| CCL4L1 \| DISEASES 84148 \| KAT8 \| DISEASES 160857 \| CCDC122 \| DISEASES 3586 \| IL10 \| DISEASES 58155 \| PTBP2 \| DISEASES 133396 \| IL31RA \| DISEASES 347273 \| MURC \| DISEASES 56244 \| BTNL2 \| DISEASES 846 \| CASR \| DISEASES 1452 \| CSNK1A1 \| DISEASES 345611 \| IRGM \| DISEASES 26298 \| EHF \| DISEASES 83695 \| RHNO1 \| DISEASES 3939 \| LDHA \| DISEASES 7421 \| VDR \| DISEASES 7732 \| RNF112 \| DISEASES 4782 \| NFIC \| DISEASES 100129060 \| SEMA3F-AS1 \| DISEASES 26774 \| SNORD80 \| DISEASES
Locus	(Waiting for update.)

Disease ID	351
Disease	leprosy
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:49) HP:0012219 \| Erythema nodosum \| 6 HP:0010783 \| Erythema \| 6 HP:0012115 \| Liver inflammation \| 4 HP:0012531 \| Pain \| 4 HP:0001369 \| Arthritis \| 4 HP:0001289 \| Confusion \| 2 HP:0000708 \| Behavioral problems \| 2 HP:0001045 \| Blotchy loss of skin color \| 2 HP:0001945 \| Fever \| 2 HP:0000739 \| Anxiety \| 1 HP:0012122 \| Anterior uveitis \| 1 HP:0200034 \| Papule \| 1 HP:0100533 \| Ocular inflammation \| 1 HP:0100699 \| Scarring \| 1 HP:0001025 \| Hives \| 1 HP:0012384 \| Nasal inflammation \| 1 HP:0002625 \| Blood clot in a deep vein \| 1 HP:0011123 \| Skin inflammation \| 1 HP:0000858 \| Menstrual irregularity \| 1 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0200036 \| Skin nodule \| 1 HP:0002860 \| Squamous cell carcinoma \| 1 HP:0001581 \| Recurrent skin infections \| 1 HP:0001101 \| Iritis \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0002835 \| Aspiration \| 1 HP:0000819 \| Diabetes mellitus \| 1 HP:0008064 \| Ichthyosis \| 1 HP:0000716 \| Depression \| 1 HP:0100661 \| Trigeminal neuralgia \| 1 HP:0005435 \| Impaired T cell function \| 1 HP:0000554 \| Uveitis \| 1 HP:0002721 \| Immunodeficiency \| 1 HP:0000709 \| Psychosis \| 1 HP:0001067 \| Neurofibromas \| 1 HP:0002615 \| Low blood pressure \| 1 HP:0010628 \| Facial palsy, unilateral or bilateral \| 1 HP:0001873 \| Low platelet count \| 1 HP:0008653 \| Crescentic glomerulonephritis \| 1 HP:0003765 \| Psoriasis \| 1 HP:0030731 \| Carcinoma \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0009027 \| Foot drop \| 1 HP:0000099 \| Glomerular nephritis \| 1 HP:0100653 \| Optic neuritis \| 1 HP:0002754 \| Bone infection \| 1 HP:0012181 \| Entrapment neuropathy \| 1 HP:0004395 \| Malnutrition \| 1 HP:0000505 \| Poor vision \| 1

Disease ID	351
Disease	leprosy
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:44) C0277787 \| stigma \| 15 C0442874 \| neuropathy \| 14 C0041296 \| tuberculosis \| 10 C0009450 \| infection \| 9 C0037284 \| skin lesions \| 8 C0037284 \| skin lesion \| 6 C0014743 \| erythema nodosum \| 6 C0343467 \| erythema nodosum leprosum \| 6 C0019158 \| hepatitis \| 4 C0003864 \| arthritis \| 4 C0030193 \| pain \| 4 C0021311 \| infections \| 4 C0027813 \| neuritis \| 3 C0152226 \| lagophthalmos \| 3 C0423716 \| neuropathic pain \| 3 C0027796 \| neuralgia \| 2 C0008582 \| chromoblastomycosis \| 2 C0019693 \| hiv infection \| 2 C0278134 \| sensory loss \| 2 C0085684 \| foot drop \| 1 C0041327 \| pulmonary tuberculosis \| 1 C0812454 \| ulnar nerve palsy \| 1 C0086815 \| plantar ulcer \| 1 C0022081 \| iritis \| 1 C0748618 \| sensory deficit \| 1 C0040053 \| thrombosis \| 1 C0024449 \| mycetoma \| 1 C0040997 \| trigeminal neuralgia \| 1 C0004936 \| mental disorders \| 1 C0000833 \| abscess \| 1 C0042109 \| urticaria \| 1 C0010266 \| cranial neuropathy \| 1 C0086815 \| plantar ulcers \| 1 C0314719 \| dry eye \| 1 C0231303 \| distress \| 1 C0037140 \| b virus infection \| 1 C0004093 \| weakness \| 1 C0403416 \| crescentic glomerulonephritis \| 1 C0021051 \| immunodeficiency \| 1 C0029443 \| osteomyelitis \| 1 C0042164 \| uveitis \| 1 C0017658 \| glomerulonephritis \| 1 C0011849 \| diabetes mellitus \| 1 C0023281 \| leishmaniasis \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:126)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs008731	16965356	7421	VDR	umls:C0023343	GAD	[The risk of leprosy occurrence conditioned by VDR polymorphism was investigated by stratifying the population of a highly endemic Brazilian region into negative and positive Mitsuda responses.]	0.004734064	2006	NA	NA	NA	NA	NA
rs10114470	NA	9966	TNFSF15	umls:C0023343	GAD	NA	0.125276948	NA	TNFSF15	9	114785492	T	C
rs1040079	21816242	135138	PACRG	umls:C0023343	BeFree	The results of our study show the association of polymorphisms rs9356058 and rs1040079 in gene PARK2/PACRG with leprosy.	0.127448483	2011	PACRG	6	162792995	A	G
rs10414149	25642632	8778	SIGLEC5	umls:C0023343	GWASCAT	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	0.12	2015	SIGLEC5	19	51624491	A	G
rs1049225	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	HLA-DQB1;HLA-DQB1-AS1	6	32659970	A	G
rs10507522	NA	144811	LACC1	umls:C0023343	GAD	NA	0.12554839	NA	NA	13	43904864	A	G
rs1063355	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	HLA-DQB1;HLA-DQB1-AS1	6	32659937	T	G
rs1071630	20617178	3118	HLA-DQA2	umls:C0023343	BeFree	We have conducted an association analysis of more than 1,500 individuals from different case-control and family studies, and observed consistent associations between genetic variants in both TLR1 and the HLA-DRB1/DQA1 regions with susceptibility to leprosy (TLR1 I602S, case-control P = 5.7 x 10(-8), OR = 0.31, 95% CI = 0.20-0.48, and HLA-DQA1 rs1071630, case-control P = 4.9 x 10(-14), OR = 0.43, 95% CI = 0.35-0.54).	0.000271442	2010	HLA-DQA1	6	32641349	T	C
rs10817758	25642632	50514	1-Dec	umls:C0023343	GWASCAT	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	0.12	2015	1-Dec	9	115381654	C	T
rs11174812	25642632	114134	SLC2A13	umls:C0023343	GWASCAT	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	0.12	2015	SLC2A13	12	40031285	C	T
rs11362	19460328	1672	DEFB1	umls:C0023343	BeFree	A study was done on the association of three single nucleotide polymorphisms (SNPs) in the beta-defensin 1 gene (DEFB1) - 668 C/G (-44 C/G or rs1800972; in 5' UTR), 692 A/G (-20 A/G or rs11362; in 5' UTR) and A1836G (rs1800971; in 3' UTR) - with leprosy susceptibility per se and clinical leprosy variants.	0.000271442	2009	DEFB1	8	6877877	C	T
rs121917864	15726416	7097	TLR2	umls:C0023343	BeFree	TLR2 Arg677Trp polymorphism in leprosy: revisited.	0.131639663	2005	TLR2	4	153704936	C	T
rs1554286	21917900	3586	IL10	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.015092462	2011	IL10	1	206770888	A	G
rs1554286	21917900	3569	IL6	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.003181358	2011	IL10	1	206770888	A	G
rs1554286	21917900	7048	TGFBR2	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL10	1	206770888	A	G
rs1554286	21917900	3588	IL10RB	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL10	1	206770888	A	G
rs16870907	NA	6891	TAP2	umls:C0023343	GAD	NA	0.002638474	NA	TAP2	6	32822030	C	T
rs16948876	22019778	1540	CYLD	umls:C0023343	GAD	[Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.]	0.002367032	2011	NA	16	50820507	G	A
rs17212090	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32683032	C	T
rs17212420	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32684623	C	T
rs17235409	20578522	6556	SLC11A1	umls:C0023343	BeFree	To determine the association of Nramp1/Slc11a1 with tuberculosis and leprosy, we analyzed using polymerase chain reaction restriction fragment length polymorphisms three variants (D543N, 3'UTR and INT4) of Nramp1/Slc11a1 gene in 58 tuberculosis patients (mean age, 34.0 +/- 13.1), 42 leprosy patients (mean age, 35.0 +/- 14.3) and 198 healthy controls (mean age, 32.0 +/- 12.9) from South Sulawesi, Indonesia.	0.136721114	2010	SLC11A1	2	218395009	G	A,C
rs17235409	17624216	7473	WNT3	umls:C0023343	BeFree	The polymorphisms of TNF alpha at -238, -308, and NRAMP1 at INT4, D543N, and3' UTR were examined in 37 patients with leprosy (24 multibacillary and 13 paucibacillary) and 140 healthy controls.	0.000542884	2007	SLC11A1	2	218395009	G	A,C
rs17235409	17624216	92105	INTS4	umls:C0023343	BeFree	The polymorphisms of TNF alpha at -238, -308, and NRAMP1 at INT4, D543N, and3' UTR were examined in 37 patients with leprosy (24 multibacillary and 13 paucibacillary) and 140 healthy controls.	0.000542884	2007	SLC11A1	2	218395009	G	A,C
rs1800797	21917900	3586	IL10	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.015092462	2011	IL6;LOC541472	7	22726602	A	G
rs1800797	21917900	7048	TGFBR2	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL6;LOC541472	7	22726602	A	G
rs1800797	21917900	3588	IL10RB	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL6;LOC541472	7	22726602	A	G
rs1800797	21917900	3569	IL6	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.003181358	2011	IL6;LOC541472	7	22726602	A	G
rs1800871	21917900	3569	IL6	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.003181358	2011	IL10	1	206773289	A	G
rs1800871	21917900	3586	IL10	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.015092462	2011	IL10	1	206773289	A	G
rs1800871	21917900	3588	IL10RB	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL10	1	206773289	A	G
rs1800871	21917900	7048	TGFBR2	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL10	1	206773289	A	G
rs1800872	21917900	3586	IL10	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.015092462	2011	IL10	1	206773062	T	G
rs1800872	21917900	3588	IL10RB	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL10	1	206773062	T	G
rs1800872	21917900	7048	TGFBR2	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL10	1	206773062	T	G
rs1800872	21917900	3569	IL6	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.003181358	2011	IL10	1	206773062	T	G
rs1800971	19460328	1672	DEFB1	umls:C0023343	BeFree	A study was done on the association of three single nucleotide polymorphisms (SNPs) in the beta-defensin 1 gene (DEFB1) - 668 C/G (-44 C/G or rs1800972; in 5' UTR), 692 A/G (-20 A/G or rs11362; in 5' UTR) and A1836G (rs1800971; in 3' UTR) - with leprosy susceptibility per se and clinical leprosy variants.	0.000271442	2009	DEFB1	8	6870594	T	C
rs1800972	19460328	1672	DEFB1	umls:C0023343	BeFree	A study was done on the association of three single nucleotide polymorphisms (SNPs) in the beta-defensin 1 gene (DEFB1) - 668 C/G (-44 C/G or rs1800972; in 5' UTR), 692 A/G (-20 A/G or rs11362; in 5' UTR) and A1836G (rs1800971; in 3' UTR) - with leprosy susceptibility per se and clinical leprosy variants.	0.000271442	2009	DEFB1	8	6877901	C	G
rs2024825	25642632	400757	C1orf141	umls:C0023343	GWASCAT	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	0.122638474	2015	C1orf141	1	67132294	T	C,G
rs2027856	NA	56244	BTNL2	umls:C0023343	GAD	NA	0.003181358	NA	NA	6	32434928	G	A
rs2221593	25642632	55509	BATF3	umls:C0023343	GWASCAT	Besides confirming all previously published loci, we discovered six new susceptibility loci, and further gene prioritization analysis of these loci implicated BATF3, CCDC88B and CIITA-SOCS1 as new susceptibility genes for leprosy.	0.240271442	2015	BATF3	1	212700089	C	T
rs2228048	21917900	3588	IL10RB	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	TGFBR2	3	30672350	C	T
rs2228048	21917900	3569	IL6	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.003181358	2011	TGFBR2	3	30672350	C	T
rs2228048	21917900	3586	IL10	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.015092462	2011	TGFBR2	3	30672350	C	T
rs2228048	21917900	7048	TGFBR2	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	TGFBR2	3	30672350	C	T
rs2270368	25642632	124460	SNX20	umls:C0023343	GWASCAT	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	0.124734064	2015	SNX20	16	50680424	G	A
rs2275606	22019778	79747	ADGB	umls:C0023343	GWASCAT	Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.	0.122638474	2011	ADGB;LOC101928661	6	146597814	G	A
rs2275606	22019778	101928661	LOC101928661	umls:C0023343	GWASCAT	Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.	0.12	2011	ADGB;LOC101928661	6	146597814	G	A
rs2275606	22019778	79747	ADGB	umls:C0023343	GAD	[Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.]	0.122638474	2011	ADGB;LOC101928661	6	146597814	G	A
rs2275848	17825431	4814	NINJ1	umls:C0023343	BeFree	Ninjurin 1 asp110ala single nucleotide polymorphism is associated with protection in leprosy nerve damage.	0.000542884	2007	NINJ1	9	93125038	G	T
rs2395173	NA	56244	BTNL2	umls:C0023343	GAD	NA	0.003181358	NA	NA	6	32437082	A	G
rs2524068	NA	3107	HLA-C	umls:C0023343	GAD	NA	0.005276948	NA	NA	6	31277284	G	T
rs2524070	NA	3107	HLA-C	umls:C0023343	GAD	NA	0.005276948	NA	NA	6	31276743	G	A
rs2524073	NA	3107	HLA-C	umls:C0023343	GAD	NA	0.005276948	NA	NA	6	31276458	G	A
rs2647012	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32696681	T	C
rs2733954	25642632	1327	COX4I1	umls:C0023343	GWASCAT	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	0.12	2015	COX4I1	16	85802650	T	C
rs2844573	24152261	100507436	MICA	umls:C0023343	BeFree	Genomewide association analysis showed that SNP rs2844573, located between the HLA-B and MICA loci, was significantly associated with the dapsone hypersensitivity syndrome among patients with leprosy (odds ratio, 6.18; P=3.84×10(-13)).	0.001085767	2013	NA	6	31367677	A	C
rs2856695	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32684117	A	G
rs2856717	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32702531	A	G
rs2856725	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32698961	C	T
rs2858305	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32702687	G	T
rs28891406	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32672559	G	A
rs2910164	25187983	406938	MIR146A	umls:C0023343	BeFree	Pre-miR-146a (rs2910164 G>C) single nucleotide polymorphism is genetically and functionally associated with leprosy.	0.000271442	2014	LOC285628;MIR146A	5	160485411	C	G
rs3088362	NA	160857	CCDC122	umls:C0023343	GAD	NA	0.002638474	NA	CCDC122	13	43859494	C	A
rs3104405	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32714531	C	A
rs3129720	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32695854	T	C
rs3135338	NA	56244	BTNL2	umls:C0023343	GAD	NA	0.003181358	NA	NA	6	32433440	C	T
rs3171425	21917900	3569	IL6	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.003181358	2011	IL10RB	21	33296442	A	G
rs3171425	21917900	7048	TGFBR2	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL10RB	21	33296442	A	G
rs3171425	21917900	3588	IL10RB	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL10RB	21	33296442	A	G
rs3171425	21917900	3586	IL10	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.015092462	2011	IL10RB	21	33296442	A	G
rs3762318	22019778	400757	C1orf141	umls:C0023343	GWASCAT	Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.	0.122638474	2011	C1orf141	1	67131436	G	A
rs3762318	22019778	400757	C1orf141	umls:C0023343	GAD	[Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.]	0.122638474	2011	C1orf141	1	67131436	G	A
rs3764147	20018961	144811	LACC1	umls:C0023343	GWASCAT	Genomewide association study of leprosy.	0.12554839	2009	LACC1	13	43883789	A	G
rs3764147	20018961	144811	LACC1	umls:C0023343	GAD	[Variants of genes in the NOD2-mediated signaling pathway (which regulates the innate immune response) are associated with susceptibility to infection with M. leprae.]	0.12554839	2009	LACC1	13	43883789	A	G
rs3764147	NA	144811	LACC1	umls:C0023343	GAD	NA	0.12554839	NA	LACC1	13	43883789	A	G
rs40457	20018961	8767	RIPK2	umls:C0023343	GAD	[Variants of genes in the NOD2-mediated signaling pathway (which regulates the innate immune response) are associated with susceptibility to infection with M. leprae.]	0.122638474	2009	NA	8	89811459	A	G
rs42490	20018961	8767	RIPK2	umls:C0023343	GWASCAT	Genomewide association study of leprosy.	0.122638474	2009	RIPK2	8	89766285	G	A
rs42490	20018961	8767	RIPK2	umls:C0023343	GAD	[Variants of genes in the NOD2-mediated signaling pathway (which regulates the innate immune response) are associated with susceptibility to infection with M. leprae.]	0.122638474	2009	RIPK2	8	89766285	G	A
rs4366152	25642632	9966	TNFSF15	umls:C0023343	GWASCAT	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	0.125276948	2015	TNFSF15	9	114802595	T	C
rs4538747	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32689557	T	A
rs4833095	19456232	7096	TLR1	umls:C0023343	BeFree	Polymorphism N248S in the human Toll-like receptor 1 gene is related to leprosy and leprosy reactions.	0.128458305	2009	TLR1	4	38798089	T	C
rs4833095	23547143	7096	TLR1	umls:C0023343	BeFree	Toll-like receptor 1 N248S single-nucleotide polymorphism is associated with leprosy risk and regulates immune activation during mycobacterial infection.	0.128458305	2013	TLR1	4	38798089	T	C
rs5000634	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32695787	A	G
rs538147	22019778	8986	RPS6KA4	umls:C0023343	GAD	[Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.]	0.002367032	2011	RPS6KA4	11	64362250	G	A
rs5743618	20617178	3118	HLA-DQA2	umls:C0023343	BeFree	We have conducted an association analysis of more than 1,500 individuals from different case-control and family studies, and observed consistent associations between genetic variants in both TLR1 and the HLA-DRB1/DQA1 regions with susceptibility to leprosy (TLR1 I602S, case-control P = 5.7 x 10(-8), OR = 0.31, 95% CI = 0.20-0.48, and HLA-DQA1 rs1071630, case-control P = 4.9 x 10(-14), OR = 0.43, 95% CI = 0.35-0.54).	0.000271442	2010	TLR1	4	38797027	C	A
rs6457617	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32696074	C	T
rs6478108	20018961	9966	TNFSF15	umls:C0023343	GAD	[Variants of genes in the NOD2-mediated signaling pathway (which regulates the innate immune response) are associated with susceptibility to infection with M. leprae.]	0.125276948	2009	TNFSF15	9	114796423	C	T
rs6478108	NA	9966	TNFSF15	umls:C0023343	GAD	NA	0.125276948	NA	TNFSF15	9	114796423	C	T
rs6478108	20018961	9966	TNFSF15	umls:C0023343	GWASCAT	Genomewide association study of leprosy.	0.125276948	2009	TNFSF15	9	114796423	C	T
rs6478109	NA	9966	TNFSF15	umls:C0023343	GAD	NA	0.125276948	NA	TNFSF15	9	114806486	A	G
rs663743	25642632	283234	CCDC88B	umls:C0023343	GWASCAT	Besides confirming all previously published loci, we discovered six new susceptibility loci, and further gene prioritization analysis of these loci implicated BATF3, CCDC88B and CIITA-SOCS1 as new susceptibility genes for leprosy.	0.240271442	2015	CCDC88B;LOC102723878	11	64340263	G	A
rs663743	25642632	102723878	LOC102723878	umls:C0023343	GWASCAT	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	0.12	2015	CCDC88B;LOC102723878	11	64340263	G	A
rs687582	NA	144811	LACC1	umls:C0023343	GAD	NA	0.12554839	NA	NA	13	43933553	T	C
rs7194886	NA	124460	SNX20	umls:C0023343	GAD	NA	0.124734064	NA	NA	16	50691282	C	T
rs7281762	21917900	3569	IL6	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.003181358	2011	IL10RB	21	33297267	G	A
rs7281762	21917900	3588	IL10RB	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL10RB	21	33297267	G	A
rs7281762	21917900	3586	IL10	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.015092462	2011	IL10RB	21	33297267	G	A
rs7281762	21917900	7048	TGFBR2	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	IL10RB	21	33297267	G	A
rs73058713	25642632	1016	CDH18	umls:C0023343	GWASCAT	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	0.12	2015	CDH18	5	20374104	C	A
rs744751	21917900	3586	IL10	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.015092462	2011	TGFBR2	3	30694445	G	A
rs744751	21917900	3569	IL6	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.003181358	2011	TGFBR2	3	30694445	G	A
rs744751	21917900	7048	TGFBR2	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	TGFBR2	3	30694445	G	A
rs744751	21917900	3588	IL10RB	umls:C0023343	BeFree	Significant associations (P < .05) were observed for 8 polymorphisms (rs1800871, rs1800872, and rs1554286 of IL-10; rs3171425 and rs7281762 of IL-10RB; rs2228048 and rs744751 of TGFBR2; and rs1800797 of IL-6) with leprosy.	0.000271442	2011	TGFBR2	3	30694445	G	A
rs76886731	25642632	9173	IL1RL1	umls:C0023343	GWASCAT	Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.	0.12	2015	IL1RL1	2	102328956	A	T
rs7759127	NA	3107	HLA-C	umls:C0023343	GAD	NA	0.005276948	NA	HLA-C;LOC101929772	6	31273211	T	G
rs7866342	NA	9966	TNFSF15	umls:C0023343	GAD	NA	0.125276948	NA	NA	9	114865289	G	T
rs9268528	NA	56244	BTNL2	umls:C0023343	GAD	NA	0.003181358	NA	NA	6	32415331	A	G
rs9268542	NA	56244	BTNL2	umls:C0023343	GAD	NA	0.003181358	NA	NA	6	32416944	A	G
rs9268585	NA	56244	BTNL2	umls:C0023343	GAD	NA	0.003181358	NA	NA	6	32429626	T	G
rs9268589	NA	56244	BTNL2	umls:C0023343	GAD	NA	0.003181358	NA	NA	6	32430425	G	A
rs9268615	NA	56244	BTNL2	umls:C0023343	GAD	NA	0.003181358	NA	NA	6	32435112	G	A
rs9274407	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	NA	NA	NA	NA
rs9274689	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32669153	T	C
rs9274741	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32670217	T	C
rs9274759	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32670538	G	A
rs9275141	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32683340	T	G
rs9275224	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32692101	A	G
rs9275245	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32693166	A	G
rs9275596	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32713854	C	T
rs9302752	NA	124460	SNX20	umls:C0023343	GAD	NA	0.124734064	NA	NA	16	50685192	T	C
rs9302752	20018961	64127	NOD2	umls:C0023343	GAD	[Genomewide association study of leprosy.]	0.009272631	2009	NA	16	50685192	T	C
rs9302752	20018961	124460	SNX20	umls:C0023343	GAD	[Variants of genes in the NOD2-mediated signaling pathway (which regulates the innate immune response) are associated with susceptibility to infection with M. leprae.]	0.124734064	2009	NA	16	50685192	T	C
rs9356058	21816242	135138	PACRG	umls:C0023343	BeFree	The results of our study show the association of polymorphisms rs9356058 and rs1040079 in gene PARK2/PACRG with leprosy.	0.127448483	2011	PACRG	6	162730367	C	T
rs9356058	21816242	5071	PARK2	umls:C0023343	BeFree	The results of our study indicate that exposure to leprosy and mortality in the population caused by leprosy on Mljet resulted in the selection of rs9356058 protective C allele in the PARK2 gene, while this was not observed in the two control groups.	0.127448483	2011	PACRG	6	162730367	C	T
rs9357152	NA	3119	HLA-DQB1	umls:C0023343	GAD	NA	0.007729856	NA	NA	6	32697183	A	G
rs9501626	NA	56244	BTNL2	umls:C0023343	GAD	NA	0.003181358	NA	NA	6	32432567	C	A

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:151)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	26779270	rs4659374	C	T	rs4659374	22019778	4.95E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	DHDDS
1	56745004	rs1581995	C	T	rs1581995	22019778	1.44E-05	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	G	NA
1	67597119	rs3762318	G	A	rs3762318	22019778	3.00E-11	NA	1.45	[1.30-1.61]	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	rs3762318-A	Research Support, Non-U.S. Gov't	T	NA
1	67652984	rs6588248	T	G	rs6588248	22019778	8.81E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	IL23R
1	231220364	rs4388693	G	A	rs4388693	pha002872	3.06E-06	phs000217	1.69	[1.37-2.08]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
2	158893323	rs7605276	T	G	rs7605276	22019778	7.11E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	UPP2
3	16233242	rs11128786	T	C	rs11128786	22019778	1.84E-05	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	GALNTL2
3	16581660	rs3856834	T	C	rs3856834	22019778	5.28E-13	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	NA
3	46728659	rs7633016	G	A	rs7633016	pha002872	3.19E-06	phs000217	1.52	[1.28-1.82]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	ALS2CL	intron	NM_147129
3	46730749	rs4076927	A	G	rs4076927	pha002872	2.53E-06	phs000217	1.53	[1.28-1.82]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	ALS2CL	intron	NM_147129
4	124784773	rs3097940	C	T	rs3097940	22019778	1.13E-08	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	LOC285419
5	18624481	rs1390566	C	T	rs1390566	pha002872	9.56E-06	phs000217	1.44	[1.22-1.69]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
5	18629409	rs1845830	G	A	rs1845830	pha002872	9.81E-06	phs000217	1.44	[1.22-1.69]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
5	35254610	rs1587601	A	G	rs1587601	22019778	3.78E-09	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	NA
5	73159601	rs6869486	T	C	rs6869486	pha002872	4.61E-06	phs000217	1.48	[1.26-1.75]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	RGNEF	intron	NM_001177693
5	123296147	rs2250107	G	A	rs2250107	pha002872	3.01E-06	phs000217	2.13	[1.54-2.94]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	30889260	rs2517467	G	A	rs2517467	pha002872	8.78E-06	phs000217	1.49	[1.25-1.77]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	VARS2	intron	NM_020442
6	30890871	rs753725	T	C	rs753725	pha002872	1.05E-05	phs000217	1.48	[1.24-1.77]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	VARS2	intron	NM_020442
6	30894759	rs2532934	G	A	rs2532934	pha002872	8.78E-06	phs000217	1.49	[1.25-1.77]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	31081409	rs1265048	T	C	rs1265048	pha002872	5.92E-06	phs000217	1.47	[1.25-1.72]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	C6orf15	nearGene-5	NM_014070
6	31090583	rs542150497	C	T	rs9295953	pha002872	2.87E-06	phs000217	1.99	[1.49-2.65]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	PSORS1C1	intron	NM_014068
6	31090583	rs9295953	C	T	rs9295953	pha002872	2.87E-06	phs000217	1.99	[1.49-2.65]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	PSORS1C1	intron	NM_014068
6	31240988	rs7759127	T	G	rs7759127	20018961	1.50E-07	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	HLA-C
6	31240988	rs7759127	T	G	rs7759127	pha002872	1.50E-07	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	HLA-C	nearGene-5	XM_003403570
6	31244235	rs2524073	G	A	rs2524073	pha002872	2.71E-07	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	31244520	rs2524070	G	A	rs2524070	20018961	1.97E-06	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	NA
6	31244520	rs2524070	G	A	rs2524070	pha002872	1.97E-06	phs000217	1.79	[1.41-2.28]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	31245061	rs2524068	G	T	rs2524068	pha002872	2.40E-06	phs000217	1.78	[1.40-2.26]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	31255424	rs2853930	A	C	rs2853930	20018961	4.74E-07	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	NA
6	31255424	rs2853930	A	C	rs2853930	pha002872	4.74E-07	phs000217	1.91	[1.48-2.46]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	31255541	rs2524050	T	C	rs2524050	pha002872	4.74E-07	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	31259137	rs1819788	T	C	rs1819788	pha002872	3.16E-06	phs000217	1.86	[1.43-2.41]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	31264912	rs2524132	G	A	rs2524132	20018961	1.95E-07	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	NA
6	31264912	rs2524132	G	A	rs2524132	pha002872	1.95E-07	phs000217	1.95	[1.51-2.50]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	31265146	rs2853924	A	T	rs2853924	pha002872	2.31E-07	phs000217	1.11	[0.93-1.32]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	31266299	rs16899202	G	C	rs16899202	pha002872	5.26E-06	phs000217	1.83	[1.41-2.37]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	31271601	rs9264868	A	G	rs9264868	20018961	1.18E-07	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	G,A	NA
6	31271601	rs9264868	A	G	rs9264868	pha002872	1.18E-07	phs000217	2.02	[1.58-2.58]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G,A	NA	NA	NA
6	31271630	rs9264869	A	G	rs9264869	pha002872	1.95E-07	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A,G	NA	NA	NA
6	31271662	rs9264870	G	A	rs9264870	pha002872	1.95E-07	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A,G	NA	NA	NA
6	31271958	rs9264885	G	C,T	rs9264885	pha002872	6.30E-07	phs000217	1.9	[1.48-2.44]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	32343369	rs3117106	T	C	rs3117106	pha002872	8.77E-08	phs000217	1.74	[1.42-2.13]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32383108	rs9268528	A	G	rs9268528	pha002872	3.12E-06	phs000217	1.49	[1.27-1.75]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32384721	rs9268542	A	G	rs9268542	pha002872	3.12E-06	phs000217	1.49	[1.27-1.75]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32397403	rs9268585	T	G	rs9268585	pha002872	9.27E-06	phs000217	1.45	[1.23-1.69]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	32398202	rs9268589	G	A	rs9268589	pha002872	1.45E-06	phs000217	1.49	[1.27-1.76]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	32400344	rs9501626	C	A	rs9501626	pha002872	1.39E-09	phs000217	1.9	[1.54-2.34]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32401217	rs3135338	C	T	rs3135338	pha002872	1.31E-09	phs000217	1.73	[1.45-2.07]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A,G	NA	NA	NA
6	32402705	rs2027856	G	A	rs2027856	pha002872	1.11E-09	phs000217	1.91	[1.55-2.35]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32402889	rs9268615	G	A	rs9268615	pha002872	1.46E-06	phs000217	1.49	[1.27-1.76]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	32404859	rs2395173	A	G	rs2395173	pha002872	1.31E-09	phs000217	1.73	[1.45-2.07]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	32406342	rs3129871	A	C	rs3129871	pha002872	1.75E-07	phs000217	1.58	[1.33-1.88]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	HLA-DRA	nearGene-5	NM_019111
6	32418031	rs6937545	A	C	rs6937545	pha002872	4.29E-06	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32420179	rs7754768	C	T	rs7754768	pha002872	1.21E-06	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	32424882	rs7763262	T	C	rs7763262	pha002872	4.29E-06	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32519005	rs28490179	C	T	rs28490179	20018961	1.42E-13	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	NA
6	32519005	rs28490179	C	T	rs28490179	pha002872	1.42E-13	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	32540041	rs9269329	T	C	rs9269329	pha002872	1.94E-16	phs000217	2.18	[1.80-2.63]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32558946	rs9270467	G	A	rs9270467	pha002872	7.00E-17	phs000217	2.19	[1.82-2.63]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32570839	rs9270856	A	G	rs9270856	20018961	3.56E-17	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	LOC100507709
6	32570839	rs9270856	A	G	rs9270856	pha002872	3.56E-17	phs000217	2.21	[1.83-2.66]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	LOC100507709	intron	XM_003119260
6	32573991	rs9270984	T	G	rs9270984	pha002872	2.73E-15	phs000217	2.14	[1.77-2.59]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	LOC100507709	intron	XM_003119260
6	32575369	rs9271055	G	T	rs9271055	pha002872	2.22E-15	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	LOC100507709	nearGene-5	XM_003119259
6	32576478	rs9271100	T	C	rs9271100	pha002872	4.92E-17	phs000217	2.19	[1.82-2.64]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	32577889	rs9271170	T	C	rs9271170	pha002872	4.92E-17	phs000217	2.19	[1.82-2.64]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	32582075	rs642093	G	A	rs642093	pha002872	1.10E-08	phs000217	1.72	[1.43-2.08]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	32583742	rs9271348	G	A	rs9271348	20018961	1.71E-15	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	NA
6	32583742	rs9271348	G	A	rs9271348	pha002872	1.71E-15	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32586854	rs9271366	G	A	rs9271366	20018961	1.46E-17	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	NA
6	32586854	rs9271366	G	A	rs9271366	pha002872	1.46E-17	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32602482	rs3104369	T	C	rs3104369	pha002872	9.94E-09	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A,G	NA	NA	NA
6	32615710	rs17612633	G	C	rs17612633	pha002872	6.97E-13	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	32620283	rs17843604	C	T	rs17843604	pha002872	2.52E-10	phs000217	1.69	[1.45-2.00]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32620622	rs17612858	A	T	rs17612858	pha002872	1.24E-10	phs000217	1.79	[1.52-2.13]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32625869	rs9273349	T	C	rs9273349	pha002872	8.31E-13	phs000217	1.83	[1.55-2.15]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	32627714	rs1063355	T	G	rs1063355	pha002872	8.09E-13	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	HLA-DQB1	UTR-3	NM_002123
6	32627747	rs1049225	A	G	rs1049225	pha002872	3.04E-11	phs000217	1.08	[0.78-1.49]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	HLA-DQB1	UTR-3	NM_002123
6	32632832	rs9274407	A	T	rs9274407	pha002872	6.72E-08	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	HLA-DQB1	missense	NM_002123
6	32636930	rs9274689	T	C	rs9274689	pha002872	6.50E-09	phs000217	1.64	[1.39-1.93]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C,T	NA	NA	NA
6	32637994	rs9274741	T	C	rs9274741	pha002872	4.72E-10	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32638315	rs9274759	G	A	rs9274759	pha002872	7.24E-10	phs000217	1.76	[1.49-2.09]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	32640336	rs28891406	G	A	rs28891406	pha002872	1.62E-09	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	32650809	rs17212090	C	T	rs17212090	pha002872	7.46E-10	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32651117	rs9275141	T	G	rs9275141	pha002872	2.61E-10	phs000217	1.74	[1.47-2.07]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	32651894	rs2856695	A	G	rs2856695	pha002872	7.66E-08	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32652400	rs17212420	C	T	rs17212420	pha002872	1.11E-09	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32657334	rs4538747	T	A	rs4538747	pha002872	6.53E-10	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	32659878	rs9275224	A	G	rs9275224	pha002872	2.32E-10	phs000217	1.69	[1.45-2.00]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G,A	NA	NA	NA
6	32660943	rs9275245	A	G	rs9275245	pha002872	2.28E-10	phs000217	1.69	[1.45-2.00]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32663564	rs5000634	A	G	rs5000634	pha002872	7.40E-12	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	32663631	rs3129720	T	C	rs3129720	pha002872	4.91E-11	phs000217	1.93	[1.59-2.35]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32663851	rs6457617	C	T	rs6457617	pha002872	1.31E-08	phs000217	NA	NA	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	32664458	rs2647012	T	C	rs2647012	pha002872	3.97E-08	phs000217	1.64	[1.38-1.96]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
6	32664960	rs9357152	A	G	rs9357152	pha002872	1.80E-08	phs000217	1.67	[1.39-1.96]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32666738	rs2856725	C	T	rs2856725	pha002872	2.05E-08	phs000217	1.67	[1.40-1.99]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32670308	rs2856717	A	G	rs2856717	pha002872	1.70E-07	phs000217	1.6	[1.34-1.91]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32670464	rs2858305	G	T	rs2858305	pha002872	1.70E-07	phs000217	1.6	[1.34-1.91]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32681631	rs9275596	C	T	rs9275596	pha002872	1.21E-07	phs000217	1.66	[1.38-1.99]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T,C	NA	NA	NA
6	32682308	rs3104405	C	A	rs3104405	pha002872	3.47E-06	phs000217	1.52	[1.27-1.81]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
6	32745043	rs9276644	T	C	rs9276644	pha002872	2.04E-06	phs000217	1.56	[1.32-1.89]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
6	32784676	rs2071554	C	T	rs2071554	pha002872	2.30E-07	phs000217	1.92	[1.49-2.47]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	HLA-DOB	missense	NM_002120
6	32788511	rs9784758	T	C	rs9784758	pha002872	2.30E-07	phs000217	1.92	[1.49-2.47]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
6	32789807	rs16870907	C	T	rs16870907	pha002872	2.46E-06	phs000217	1.92	[1.45-2.53]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	TAP2	UTR-3	NM_018833
6	76174857	rs2951916	A	G	rs2951916	22019778	3.87E-16	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	FILIP1
6	130190985	rs2127706	G	A	rs2127706	22019778	5.12E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	G	NA
6	146918950	rs2275606	G	A	rs2275606	22019778	4.00E-14	NA	1.3	[1.21-1.39]	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	rs2275606-A	Research Support, Non-U.S. Gov't	G	NA
8	90778513	rs42490	G	A	rs42490	20018961	1.00E-16	NA	1.32	[1.23-1.41]	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	rs42490-G	Research Support, Non-U.S. Gov't	G	RIPK2
8	90778513	rs42490	G	A	rs42490	22019778	1.01E-07	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	G	RIPK2
8	90823687	rs40457	A	G	rs40457	20018961	1.00E-12	NA	1.3	[1.20-1.39]	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	rs40457-A	Research Support, Non-U.S. Gov't	A	NA
9	17761379	rs1886589	C	T	rs1886589	22019778	5.13E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	SH3GL2
9	17938351	rs1755289	T	C	rs1755289	pha002872	9.84E-06	phs000217	1.45	[1.22-1.69]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
9	117493017	rs10982385	T	G	rs10982385	20018961	8.73E-08	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	NA
9	117538334	rs4574921	C	T	rs4574921	20018961	2.17E-16	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	NA
9	117547772	rs10114470	T	C	rs10114470	20018961	5.42E-14	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	TNFSF15
9	117547772	rs10114470	T	C	rs10114470	pha002872	4.08E-06	phs000217	1.47	[1.25-1.72]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	TNFSF15	UTR-3	NM_005118
9	117558703	rs6478108	C	T	rs6478108	20018961	3.00E-21	NA	1.37	[1.28-1.46]	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	rs6478108-A	Research Support, Non-U.S. Gov't	T	TNFSF15
9	117558703	rs6478108	C	T	rs6478108	22019778	7.01E-09	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	TNFSF15
9	117558703	rs6478108	C	T	rs6478108	pha002872	4.11E-07	phs000217	1.52	[1.30-1.79]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	TNFSF15	intron	NM_005118
9	117568766	rs6478109	A	G	rs6478109	pha002872	9.12E-08	phs000217	1.56	[1.33-1.82]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	TNFSF15	nearGene-5	NM_005118
9	117627569	rs7866342	G	T	rs7866342	pha002872	1.01E-05	phs000217	1.43	[1.22-1.69]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	T	NA	NA	NA
10	7144255	rs2462692	T	A,C,G	rs2462692	20018961	5.15E-06	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	NA
10	7144255	rs2462692	T	A,C,G	rs2462692	pha002872	1.57E-06	phs000217	3.23	[2.08-5.26]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
10	13388584	rs1004621	G	C	rs1004621	22019778	3.26E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	SEPHS1
11	64129722	rs538147	G	A	rs538147	22019778	7.00E-06	NA	1.17	[1.09-1.25]	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	rs538147-A	Research Support, Non-U.S. Gov't	G	RPS6KA4
11	64591679	rs670358	G	A	rs670358	pha002872	7.71E-06	phs000217	1.2	[0.91-1.61]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	CDC42BPG	UTR-3	NM_017525
12	25844865	rs4963910	C	T	rs4963910	pha002872	8.37E-06	phs000217	3.23	[1.92-5.26]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
12	40552417	rs1873613	T	C	rs1873613	20018961	5.10E-05	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	NA
13	44397815	rs9533634	T	C	rs9533634	20018961	4.77E-12	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	T	NA
13	44433630	rs3088362	C	A	rs3088362	20018961	1.36E-31	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	CCDC122
13	44433630	rs3088362	C	A	rs3088362	22019778	3.84E-13	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	CCDC122
13	44433630	rs3088362	C	A	rs3088362	pha002872	1.37E-09	phs000217	1.72	[1.44-2.05]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	CCDC122	intron	NM_144974
13	44457925	rs3764147	A	G	rs3764147	20018961	4.00E-54	NA	1.68	[1.57-1.80]	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	rs3764147-G	Research Support, Non-U.S. Gov't	A	LACC1
13	44457925	rs3764147	A	G	rs3764147	22019778	3.83E-18	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	LACC1
13	44457925	rs3764147	A	G	rs3764147	pha002872	1.21E-10	phs000217	1.75	[1.48-2.07]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	LACC1	missense	NM_153218
13	44479000	rs10507522	A	G	rs10507522	20018961	4.64E-24	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	NA
13	44479000	rs10507522	A	G	rs10507522	pha002872	1.33E-08	phs000217	1.72	[1.43-2.04]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	NA	NA	NA
13	44507689	rs687582	T	C	rs687582	pha002872	6.19E-06	phs000217	1.45	[1.23-1.69]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	G	NA	NA	NA
14	52355387	rs10133203	A	G	rs10133203	pha002872	1.06E-05	phs000217	1.67	[1.32-2.08]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	A	GNG2	intron	NM_053064
14	57204059	rs4901735	A	G	rs4901735	22019778	1.10E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	NA
14	96013584	rs9323927	A	G	rs9323927	22019778	1.65E-05	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	A	NA
16	50719103	rs9302752	T	C	rs9302752	20018961	4.00E-40	NA	1.59	[1.49-1.71]	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	rs9302752-G	Research Support, Non-U.S. Gov't	C	NA
16	50719103	rs9302752	T	C	rs9302752	22019778	4.24E-18	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	NA
16	50719103	rs9302752	T	C	rs9302752	pha002872	1.45E-12	phs000217	1.86	[1.57-2.21]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
16	50725193	rs7194886	C	T	rs7194886	20018961	1.77E-30	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	NA
16	50725193	rs7194886	C	T	rs7194886	pha002872	2.42E-07	phs000217	1.78	[1.43-2.20]	NA	ALL(0)	ALL(0)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	NA	C	NA	NA	NA
16	50737980	rs8057341	A	G	rs8057341	20018961	5.53E-05	NA	NA	NA	706 Han Chinese cases; 1,225 Han Chinese controls	Han Chinese(1931)	ALL(1931)	ASN(1931)	ALL(1931)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	G	NOD2
16	50854418	rs16948876	G	A	rs16948876	22019778	2.00E-10	NA	1.56	[1.36-1.79]	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	rs16948876-A	Research Support, Non-U.S. Gov't	G	NA
16	65891108	rs8060933	G	T	rs8060933	22019778	4.09E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	G	NA
16	77309963	rs4411511	G	A	rs4411511	22019778	9.55E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	G	NA
20	11368551	rs8119692	G	A	rs8119692	22019778	4.54E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	G	NA
20	43923473	rs2743396	T	C	rs2743396	22019778	1.95E-06	NA	NA	NA	706 Chinese ancestry cases; 5,581 Chinese ancestry controls	Chinese(6287)	ALL(6287)	ASN(6287)	ALL(6287)	Leprosy	HPOID:0002955	Granulomatosis	DOID:1024	leprosy	D007918	Leprosy	EFOID:0001054	leprosy	Leprosy	NA	Research Support, Non-U.S. Gov't	C	MATN4

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:5)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0023343	chloroquine	D002738	1954/5/7	leprosy	MESH:D007918	therapeutic	9715604
C0023343	clofazimine	D002991	2030-63-9	leprosy	MESH:D007918	therapeutic	16015260
C0023343	dapsone	D003622	80-08-0	leprosy	MESH:D007918	therapeutic	1184260
C0023343	rifampin	D012293	13292-46-1	leprosy	MESH:D007918	therapeutic	16015260
C0023343	thalidomide	D013792	50-35-1	leprosy	MESH:D007918	therapeutic	12483964

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)