PedAM

Pediatric Disease Annotations & Medicines


	lassa fever

Disease ID	86
Disease	lassa fever
Definition	An acute febrile human disease caused by the LASSA VIRUS.
Synonym	fever lassa fever, lassa fevers, lassa lassa fever (disorder) lassa fever [disease/finding] lassa fevers lassa hemorrhagic fever
Orphanet	ORPHANET:99824
DOID	DOID:9537
ICD10	ICD10CM:A96.2
UMLS	C0023092
MeSH	D007835
SNOMED-CT	SNOMEDCT_US_2016_09_01:19065005
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:4) C0043395 \| yellow fever \| 1 C0011860 \| type 2 diabetes mellitus \| 1 C0032371 \| poliomyelitis \| 1 C0011860 \| type 2 diabetes \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:1) DAG1 \| 1605 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:58) 10942 \| PRSS21 \| DISEASES 3883 \| KRT33A \| DISEASES 3385 \| ICAM3 \| DISEASES 9567 \| GTPBP1 \| DISEASES 6783 \| SULT1E1 \| DISEASES 79441 \| HAUS3 \| DISEASES 7251 \| TSG101 \| DISEASES 3337 \| DNAJB1 \| DISEASES 5279 \| PIGC \| DISEASES 3569 \| IL6 \| DISEASES 2995 \| GYPC \| DISEASES 7301 \| TYRO3 \| DISEASES 59067 \| IL21 \| DISEASES 10058 \| ABCB6 \| DISEASES 5371 \| PML \| DISEASES 3687 \| ITGAX \| DISEASES 4864 \| NPC1 \| DISEASES 3454 \| IFNAR1 \| DISEASES 91937 \| TIMD4 \| DISEASES 3439 \| IFNA1 \| DISEASES 10461 \| MERTK \| DISEASES 6236 \| RRAD \| DISEASES 7184 \| HSP90B1 \| DISEASES 2923 \| PDIA3 \| DISEASES 558 \| AXL \| DISEASES 3627 \| CXCL10 \| DISEASES 3669 \| ISG20 \| DISEASES 6373 \| CXCL11 \| DISEASES 1605 \| DAG1 \| DISEASES 30835 \| CD209 \| DISEASES 4843 \| NOS2 \| DISEASES 339390 \| CLEC4G \| DISEASES 29933 \| GPR132 \| DISEASES 25834 \| MGAT4C \| DISEASES 3916 \| LAMP1 \| DISEASES 3329 \| HSPD1 \| DISEASES 6672 \| SP100 \| DISEASES 8720 \| MBTPS1 \| DISEASES 3516 \| RBPJ \| DISEASES 4734 \| NEDD4 \| DISEASES 6772 \| STAT1 \| DISEASES 23038 \| WDTC1 \| DISEASES 4288 \| MKI67 \| DISEASES 959 \| CD40LG \| DISEASES 9023 \| CH25H \| DISEASES 3980 \| LIG3 \| DISEASES 23586 \| DDX58 \| DISEASES 3456 \| IFNB1 \| DISEASES 2813 \| GP2 \| DISEASES 5888 \| RAD51 \| DISEASES 27032 \| ATP2C1 \| DISEASES 344022 \| NOTO \| DISEASES 5970 \| RELA \| DISEASES 131578 \| LRRC15 \| DISEASES 30816 \| ERVW-1 \| DISEASES 1977 \| EIF4E \| DISEASES 4065 \| LY75 \| DISEASES 284424 \| MIR7-3HG \| DISEASES
Locus	(Waiting for update.)

Disease ID	86
Disease	lassa fever
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:29) HP:0400008 \| Menometrorrhagia HP:0012735 \| Cough HP:0002239 \| Gastrointestinal hemorrhage HP:0002829 \| Arthralgia HP:0001882 \| Leukopenia HP:0000988 \| Skin rash HP:0002014 \| Diarrhea HP:0002202 \| Pleural effusion HP:0006543 \| Cardiorespiratory arrest HP:0002716 \| Lymphadenopathy HP:0003326 \| Myalgia HP:0002321 \| Vertigo HP:0001945 \| Fever HP:0001254 \| Lethargy HP:0002315 \| Headache HP:0001250 \| Seizures HP:0100776 \| Recurrent pharyngitis HP:0000365 \| Hearing impairment HP:0012375 \| Chemosis HP:0100749 \| Chest pain HP:0001873 \| Thrombocytopenia HP:0012378 \| Fatigue HP:0000509 \| Conjunctivitis HP:0100540 \| Palpebral edema HP:0002017 \| Nausea and vomiting HP:0002516 \| Increased intracranial pressure HP:0005268 \| Spontaneous abortion HP:0001482 \| Subcutaneous nodule HP:0002027 \| Abdominal pain
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:4) HP:0002027 \| Abdominal pain \| 1 HP:0012531 \| Pain \| 1 HP:0001892 \| Bleeding diathesis \| 1 HP:0001945 \| Fever \| 1

Disease ID	86
Disease	lassa fever
Manually Symptom	UMLS \| Name(Total Manually Symptoms:6) C2029884 \| hearing loss C0581883 \| deafness C0019158 \| hepatitis C0019080 \| hemorrhage C0018784 \| sensorineural hearing loss C0018784 \| sensorineural deafness
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:1) C0019080 \| hemorrhage \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:1)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0001645	Sudden cardiac death	MP:0003393	decreased cardiac output;HP:0100539	Periorbital edema

Mapped by homologous gene(Total Items:1)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0002716	Lymphadenopathy	MP:0002420	abnormal adaptive immunity;HP:0000365	Hearing impairment

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0023092	ribavirin	D012254	36791-04-5	lassa fever	MESH:D007835	therapeutic	2546248

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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