PedAM
Pediatric Disease Annotations & Medicines
| large intestine adenocarcinoma | ||||
| Disease ID | 1769 |
|---|---|
| Disease | large intestine adenocarcinoma |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:8) HP:0002664 | Neoplasia | 6 HP:0006254 | Increased serum alpha-fetoprotein | 1 HP:0100273 | Colon tumor | 1 HP:0005202 | Helicobacter pylori infection | 1 HP:0002716 | Lymph node hyperplasia | 1 HP:0030731 | Carcinoma | 1 HP:0001638 | Cardiomyopathy | 1 HP:0001945 | Fever | 1 |
| Disease ID | 1769 |
|---|---|
| Disease | large intestine adenocarcinoma |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:5) C0494165 | liver metastases | 1 C0040053 | thrombosis | 1 C0009450 | infection | 1 C0494165 | liver metastasis | 1 C0494165 | hepatic metastasis | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:13) | |||||||||||||
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| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs1042522 | 18507052 | 7157 | TP53 | umls:C1319315 | BeFree | The current case-control study was conducted in order to elucidate any possible association of the single nucleotide polymorphism (SNP) of codon 72 of the p53 gene (Arg72Pro) and sporadic colorectal adenocarcinoma development in a Caucasian population in Greece. | 0.007328931 | 2008 | TP53 | 17 | 7676154 | G | T,C |
| rs1045642 | 16107775 | 4363 | ABCC1 | umls:C1319315 | BeFree | In this study, 3 genotypes of MDR1, 4 genotypes of MRP1, and 6 genotypes of MRP2 were additionally evaluated, and it was suggested that MDR1 C3435T and MRP2 G1249A were related with the susceptibility to colorectal adenocarcinoma. | 0.000542884 | 2004 | ABCB1 | 7 | 87509329 | A | T,G |
| rs1045642 | 16107775 | 5243 | ABCB1 | umls:C1319315 | BeFree | In this study, 3 genotypes of MDR1, 4 genotypes of MRP1, and 6 genotypes of MRP2 were additionally evaluated, and it was suggested that MDR1 C3435T and MRP2 G1249A were related with the susceptibility to colorectal adenocarcinoma. | 0.001085767 | 2004 | ABCB1 | 7 | 87509329 | A | T,G |
| rs1045642 | 16107775 | 4194 | MDM4 | umls:C1319315 | BeFree | In this study, 3 genotypes of MDR1, 4 genotypes of MRP1, and 6 genotypes of MRP2 were additionally evaluated, and it was suggested that MDR1 C3435T and MRP2 G1249A were related with the susceptibility to colorectal adenocarcinoma. | 0.000542884 | 2004 | ABCB1 | 7 | 87509329 | A | T,G |
| rs1045642 | 16107775 | 4437 | MSH3 | umls:C1319315 | BeFree | In this study, 3 genotypes of MDR1, 4 genotypes of MRP1, and 6 genotypes of MRP2 were additionally evaluated, and it was suggested that MDR1 C3435T and MRP2 G1249A were related with the susceptibility to colorectal adenocarcinoma. | 0.000542884 | 2004 | ABCB1 | 7 | 87509329 | A | T,G |
| rs113488022 | 23763264 | 673 | BRAF | umls:C1319315 | BeFree | Immunohistochemistry using the BRAF V600E mutation-specific monoclonal antibody VE1 is not a useful surrogate for genotyping in colorectal adenocarcinoma. | 0.002171535 | 2013 | BRAF | 7 | 140753336 | A | T,G,C |
| rs11540654 | 18507052 | 7157 | TP53 | umls:C1319315 | BeFree | The current case-control study was conducted in order to elucidate any possible association of the single nucleotide polymorphism (SNP) of codon 72 of the p53 gene (Arg72Pro) and sporadic colorectal adenocarcinoma development in a Caucasian population in Greece. | 0.007328931 | 2008 | TP53 | 17 | 7676040 | C | T,G,A |
| rs13207351 | 15522212 | 7422 | VEGFA | umls:C1319315 | BeFree | T-1498C (G-1190A) and C-7T were found to be associated with higher levels of VEGF mRNA, and may be a risk factor for the development of liver metastasis and/or prognosis of colorectal adenocarcinoma. | 0.001628651 | 2004 | VEGFA | 6 | 43770057 | A | G |
| rs2273697 | 16107775 | 4363 | ABCC1 | umls:C1319315 | BeFree | In this study, 3 genotypes of MDR1, 4 genotypes of MRP1, and 6 genotypes of MRP2 were additionally evaluated, and it was suggested that MDR1 C3435T and MRP2 G1249A were related with the susceptibility to colorectal adenocarcinoma. | 0.000542884 | 2004 | ABCC2 | 10 | 99804058 | G | A |
| rs2273697 | 16107775 | 5243 | ABCB1 | umls:C1319315 | BeFree | In this study, 3 genotypes of MDR1, 4 genotypes of MRP1, and 6 genotypes of MRP2 were additionally evaluated, and it was suggested that MDR1 C3435T and MRP2 G1249A were related with the susceptibility to colorectal adenocarcinoma. | 0.001085767 | 2004 | ABCC2 | 10 | 99804058 | G | A |
| rs2273697 | 16107775 | 4437 | MSH3 | umls:C1319315 | BeFree | In this study, 3 genotypes of MDR1, 4 genotypes of MRP1, and 6 genotypes of MRP2 were additionally evaluated, and it was suggested that MDR1 C3435T and MRP2 G1249A were related with the susceptibility to colorectal adenocarcinoma. | 0.000542884 | 2004 | ABCC2 | 10 | 99804058 | G | A |
| rs2273697 | 16107775 | 4194 | MDM4 | umls:C1319315 | BeFree | In this study, 3 genotypes of MDR1, 4 genotypes of MRP1, and 6 genotypes of MRP2 were additionally evaluated, and it was suggested that MDR1 C3435T and MRP2 G1249A were related with the susceptibility to colorectal adenocarcinoma. | 0.000542884 | 2004 | ABCC2 | 10 | 99804058 | G | A |
| rs833061 | 15522212 | 7422 | VEGFA | umls:C1319315 | BeFree | T-1498C (G-1190A) and C-7T were found to be associated with higher levels of VEGF mRNA, and may be a risk factor for the development of liver metastasis and/or prognosis of colorectal adenocarcinoma. | 0.001628651 | 2004 | VEGFA | 6 | 43769749 | C | T |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |