PedAM
Pediatric Disease Annotations & Medicines
| juvenile pilocytic astrocytoma | ||||
| Disease ID | 912 |
|---|---|
| Disease | juvenile pilocytic astrocytoma |
| Definition | A slow-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain and spinal cord. Juvenile pilocytic astrocytoma usually occurs in children and young adults. It forms in the brain more often than the spinal cord. |
| Synonym | astrocytoma, juvenile pilocytic astrocytomas, juvenile pilocytic juvenile pilocytic astrocytomas pilocytic astrocytoma, juvenile pilocytic astrocytomas, juvenile |
| DOID | |
| UMLS | C0280783 |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:1) |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:18) 2026 | ENO2 | DISEASES 6945 | MLX | DISEASES 2670 | GFAP | DISEASES 2247 | FGF2 | DISEASES 7078 | TIMP3 | DISEASES 7157 | TP53 | DISEASES 55768 | NGLY1 | DISEASES 558 | AXL | DISEASES 5604 | MAP2K1 | DISEASES 3643 | INSR | DISEASES 80381 | CD276 | DISEASES 4978 | OPCML | DISEASES 4763 | NF1 | DISEASES 4155 | MBP | DISEASES 1654 | DDX3X | DISEASES 1029 | CDKN2A | DISEASES 50863 | NTM | DISEASES 26137 | ZBTB20 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 912 |
|---|---|
| Disease | juvenile pilocytic astrocytoma |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:2) |
| Disease ID | 912 |
|---|---|
| Disease | juvenile pilocytic astrocytoma |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:1) C0018784 | sensorineural hearing loss |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:1) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs113488022 | 20806365 | 673 | BRAF | umls:C0280783 | BeFree | AZD6244 was evaluated against two JPA xenografts, BT-35 (wild-type BRAF) and BT-40 (mutant [V600E] BRAF). | 0.000271442 | 2010 | BRAF | 7 | 140753336 | A | T,G,C |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0000407 | Sensorineural hearing impairment | MP:0006330 | syndromic hearing impairment; | |
Mapped by homologous gene(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0000407 | Sensorineural hearing impairment | MP:0000010 | abnormal abdominal fat pad morphology; | |
Chemical(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |