PedAM

Pediatric Disease Annotations & Medicines


	iris disease

Disease ID	1323
Disease	iris disease
Definition	Diseases, dysfunctions, or disorders of or located in the iris.
Synonym	disease iris disease of iris disease, iris diseases iris diseases, iris disorder of iris disorder of iris (disorder) disorder of iris, nos disorders iris iris dis iris diseases iris diseases [disease/finding] iris disorder iris disorders
DOID	DOID:240
UMLS	C0022078
MeSH	D007499
SNOMED-CT	SNOMEDCT_US_2016_09_01:85478004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:4) C0020538 \| hypertension \| 1 C0017601 \| glaucoma \| 1 C0028840 \| ocular hypertension \| 1 C0206368 \| exfoliation syndrome \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:1) PAX6 \| 5080 \| GHR
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:186) 100048912 \| CDKN2B-AS1 \| DISEASES 4257 \| MGST1 \| DISEASES 4653 \| MYOC \| DISEASES 5954 \| RCN1 \| DISEASES 2928 \| GSC2 \| DISEASES 368 \| ABCC6 \| DISEASES 7049 \| TGFBR3 \| DISEASES 1472 \| CST4 \| DISEASES 7076 \| TIMP1 \| DISEASES 4313 \| MMP2 \| DISEASES 7040 \| TGFB1 \| DISEASES 7448 \| VTN \| DISEASES 4015 \| LOX \| DISEASES 847 \| CAT \| DISEASES 652 \| BMP4 \| DISEASES 6495 \| SIX1 \| DISEASES 2678 \| GGT1 \| DISEASES 9526 \| MPDU1 \| DISEASES 3859 \| KRT12 \| DISEASES 2006 \| ELN \| DISEASES 348 \| APOE \| DISEASES 2488 \| FSHB \| DISEASES 6538 \| SLC6A11 \| DISEASES 53 \| ACP2 \| DISEASES 79056 \| PRRG4 \| DISEASES 1545 \| CYP1B1 \| DISEASES 6496 \| SIX3 \| DISEASES 4016 \| LOXL1 \| DISEASES 4053 \| LTBP2 \| DISEASES 338917 \| VSX2 \| DISEASES 27443 \| CECR2 \| DISEASES 7077 \| TIMP2 \| DISEASES 10133 \| OPTN \| DISEASES 7299 \| TYR \| DISEASES 2651 \| GCNT2 \| DISEASES 1462 \| VCAN \| DISEASES 52 \| ACP1 \| DISEASES 2052 \| EPHX1 \| DISEASES 2620 \| GAS2 \| DISEASES 196294 \| IMMP1L \| DISEASES 5013 \| OTX1 \| DISEASES 392255 \| GDF6 \| DISEASES 6529 \| SLC6A1 \| DISEASES 79190 \| IRX6 \| DISEASES 1409 \| CRYAA \| DISEASES 4009 \| LMX1A \| DISEASES 4760 \| NEUROD1 \| DISEASES 213 \| ALB \| DISEASES 26610 \| ELP4 \| DISEASES 9317 \| PTER \| DISEASES 54765 \| TRIM44 \| DISEASES 146167 \| SLC38A8 \| DISEASES 161514 \| TBC1D21 \| DISEASES 3233 \| HOXD4 \| DISEASES 613 \| BCR \| DISEASES 5308 \| PITX2 \| DISEASES 8419 \| BFSP2 \| DISEASES 56246 \| MRAP \| DISEASES 30008 \| EFEMP2 \| DISEASES 196883 \| ADCY4 \| DISEASES 219902 \| TMEM136 \| DISEASES 1191 \| CLU \| DISEASES 80207 \| OPA3 \| DISEASES 23019 \| CNOT1 \| DISEASES 10782 \| ZNF274 \| DISEASES 8818 \| DPM2 \| DISEASES 4312 \| MMP1 \| DISEASES 6657 \| SOX2 \| DISEASES 977 \| CD151 \| DISEASES 2200 \| FBN1 \| DISEASES 4990 \| SIX6 \| DISEASES 7490 \| WT1 \| DISEASES 5271 \| SERPINB8 \| DISEASES 79191 \| IRX3 \| DISEASES 25834 \| MGAT4C \| DISEASES 9573 \| GDF3 \| DISEASES 6899 \| TBX1 \| DISEASES 60529 \| ALX4 \| DISEASES 81565 \| NDEL1 \| DISEASES 2301 \| FOXE3 \| DISEASES 338645 \| LUZP2 \| DISEASES 1209 \| CLPTM1 \| DISEASES 10554 \| AGPAT1 \| DISEASES 64778 \| FNDC3B \| DISEASES 395 \| ARHGAP6 \| DISEASES 6540 \| SLC6A13 \| DISEASES 5078 \| PAX4 \| DISEASES 7477 \| WNT7B \| DISEASES 6731 \| SRP72 \| DISEASES 81551 \| STMN4 \| DISEASES 2138 \| EYA1 \| DISEASES 10979 \| FERMT2 \| DISEASES 5015 \| OTX2 \| DISEASES 9672 \| SDC3 \| DISEASES 347 \| APOD \| DISEASES 57556 \| SEMA6A \| DISEASES 797 \| CALCB \| DISEASES 1413 \| CRYBA4 \| DISEASES 204 \| AK2 \| DISEASES 54899 \| PXK \| DISEASES 1121 \| CHM \| DISEASES 744 \| MPPED2 \| DISEASES 55102 \| ATG2B \| DISEASES 127343 \| DMBX1 \| DISEASES 773 \| CACNA1A \| DISEASES 10367 \| MICU1 \| DISEASES 1745 \| DLX1 \| DISEASES 26047 \| CNTNAP2 \| DISEASES 55605 \| KIF21A \| DISEASES 56259 \| CTNNBL1 \| DISEASES 5083 \| PAX9 \| DISEASES 4509 \| MT-ATP8 \| DISEASES 7052 \| TGM2 \| DISEASES 5664 \| PSEN2 \| DISEASES 7042 \| TGFB2 \| DISEASES 6648 \| SOD2 \| DISEASES 252839 \| TMEM9 \| DISEASES 54823 \| SWT1 \| DISEASES 10223 \| GPA33 \| DISEASES 1490 \| CTGF \| DISEASES 5824 \| PEX19 \| DISEASES 93183 \| PIGM \| DISEASES 7101 \| NR2E1 \| DISEASES 26227 \| PHGDH \| DISEASES 8266 \| UBL4A \| DISEASES 5309 \| PITX3 \| DISEASES 959 \| CD40LG \| DISEASES 51013 \| EXOSC1 \| DISEASES 4318 \| MMP9 \| DISEASES 50945 \| TBX22 \| DISEASES 154467 \| CCDC167 \| DISEASES 4237 \| MFAP2 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 4524 \| MTHFR \| DISEASES 84678 \| KDM2B \| DISEASES 631 \| BFSP1 \| DISEASES 390992 \| HES3 \| DISEASES 388585 \| HES5 \| DISEASES 5080 \| PAX6 \| DISEASES 55366 \| LGR4 \| DISEASES 5251 \| PHEX \| DISEASES 146 \| ADRA1D \| DISEASES 148 \| ADRA1A \| DISEASES 2762 \| GMDS \| DISEASES 2296 \| FOXC1 \| DISEASES 3651 \| PDX1 \| DISEASES 169792 \| GLIS3 \| DISEASES 10457 \| GPNMB \| DISEASES 60312 \| AFAP1 \| DISEASES 27303 \| RBMS3 \| DISEASES 7306 \| TYRP1 \| DISEASES 4017 \| LOXL2 \| DISEASES 10716 \| TBR1 \| DISEASES 1130 \| LYST \| DISEASES 22900 \| CARD8 \| DISEASES 5077 \| PAX3 \| DISEASES 1415 \| CRYBB2 \| DISEASES 5075 \| PAX1 \| DISEASES 2199 \| FBLN2 \| DISEASES 728441 \| GGT2 \| DISEASES 3778 \| KCNMA1 \| DISEASES 4052 \| LTBP1 \| DISEASES 758 \| MPPED1 \| DISEASES 100506627 \| DCDC5 \| DISEASES 3481 \| IGF2 \| DISEASES 5076 \| PAX2 \| DISEASES 7124 \| TNF \| DISEASES 51317 \| PHF21A \| DISEASES 8522 \| GAS7 \| DISEASES 3850 \| KRT3 \| DISEASES 627 \| BDNF \| DISEASES 7045 \| TGFBI \| DISEASES 4935 \| GPR143 \| DISEASES 120526 \| DNAJC24 \| DISEASES 134430 \| WDR36 \| DISEASES 346007 \| EYS \| DISEASES 11331 \| PHB2 \| DISEASES 3939 \| LDHA \| DISEASES 4522 \| MTHFD1 \| DISEASES 11217 \| AKAP2 \| DISEASES 54749 \| EPDR1 \| DISEASES 27229 \| TUBGCP4 \| DISEASES 10896 \| OCLM \| DISEASES 4782 \| NFIC \| DISEASES 100287616 \| LOXL1-AS1 \| DISEASES 51352 \| WT1-AS \| DISEASES
Locus	(Waiting for update.)

Disease ID	1323
Disease	iris disease
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:2) HP:0000501 \| Glaucoma \| 1 HP:0000822 \| Hypertension \| 1

Disease ID	1323
Disease	iris disease
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:223)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	22336277	rs3820285	C	G	rs3820285	21835309	7.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	33614162	rs3912145	T	C	rs3912145	21835309	1.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	40680128	rs12144950	A	G	rs12144950	21835309	4.80E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	56771709	rs3005884	C	T	rs3005884	23118974	6.41E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
1	75014195	rs7541513	G	A	rs7541513	21835309	2.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	82960385	rs2225083	G	A	rs2225083	23118974	9.58E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	107557477	rs6675948	C	G	rs6675948	21835309	3.80E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	114591798	rs2938334	T	C	rs2938334	21835309	2.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	158580759	rs12601	G	A	rs12601	21835309	3.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	181645227	rs3753737	G	A	rs3753737	21835309	7.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	182319935	rs2256956	G	A	rs2256956	18252221	1.56E-07	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	A
1	182543331	rs11072	A	G	rs11072	21835309	5.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	213126565	rs3002288	G	A	rs3002288	23548203	7.00E-08	Brown eye color	0.22	[0.14-0.30] unit decrease	3871 European ancestry individuals	European(3871)	ALL(3871)	EUR(3871)	ALL(3871)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs3002288-A	Research Support, N.I.H., Extramural	G	VASH2
1	213181916	rs3002284	T	C	rs3002284	21835309	8.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	235701864	rs10802790	G	C	rs10802790	21835309	5.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	25453968	rs13420827	C	G	rs13420827	21835309	1.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	74406055	rs1667601	G	T	rs1667601	21835309	2.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	74972081	rs205611	A	G	rs205611	21835309	1.00E-06	Crypts	0.12	[0.06-0.18] unit decrease	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	rs205611-A	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	80605790	rs13431891	A	G	rs13431891	23486544	4.06E-08	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	A	CTNNA2
2	85811229	rs1254901	G	A	rs1254901	21835309	3.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	99803998	rs13009147	T	G	rs13009147	21835309	7.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	101881980	rs13015194	T	G	rs13015194	21835309	1.50E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	102479029	rs3771903	G	A	rs3771903	21835309	2.80E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	102534237	rs7568226	T	A	rs7568226	21835309	1.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	102574838	rs1019031	G	T	rs1019031	21835309	2.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	102648609	rs4851531	C	T	rs4851531	21835309	3.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	131489113	rs13400337	C	T	rs13400337	21835309	6.10E-06	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	143550868	rs6712291	T	C	rs6712291	23118974	5.25E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
2	167228744	rs10930218	T	G	rs10930218	21835309	2.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	184005606	rs2675098	G	A	rs2675098	23118974	4.59E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	189588880	rs1395864	A	G	rs1395864	21835309	4.80E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	203550741	rs7577225	T	C	rs7577225	21835309	7.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	203699740	rs12053074	G	C	rs12053074	21835309	4.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	206965837	rs6718656	T	G	rs6718656	21835309	6.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	217411246	rs922987	T	C	rs922987	21835309	2.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	222280806	rs4674596	C	G	rs4674596	21835309	2.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	239306268	rs3739070	A	C	rs3739070	21835309	2.00E-12	Furrows	0.25	[0.19-0.31] unit increase	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	rs3739070-A	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	239306268	rs3739070	A	C	rs3739070	21835309	6.00E-06	Crypts	0.16	[0.10-0.22] unit decrease	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	rs3739070-A	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	46892161	rs1077216	C	T	rs1077216	21835309	2.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	48170521	rs10446426	C	G	rs10446426	21835309	2.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	58050265	rs9809315	C	T	rs9809315	23118974	2.84E-05	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	100247165	rs3924054	G	A	rs3924054	21835309	6.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	108656151	rs751298	T	C	rs751298	21835309	2.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	112512819	rs6775807	T	C	rs6775807	21835309	1.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	156915650	rs2133952	C	T	rs2133952	21835309	9.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	156962761	rs1587534	A	C	rs1587534	21835309	9.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	183601498	rs2056332	T	C	rs2056332	21835309	2.80E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	71575239	rs6813178	G	A	rs6813178	21835309	6.90E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	71583087	rs7678779	C	A	rs7678779	21835309	1.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	71695541	rs1020929	G	C	rs1020929	21835309	4.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	76550861	rs1464071	T	C	rs1464071	21835309	8.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	76684108	rs10028884	A	G	rs10028884	21835309	3.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	98950296	rs12233741	C	T	rs12233741	21835309	6.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	111030787	rs6533491	T	C	rs6533491	21835309	4.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	115805292	rs7673947	A	G	rs7673947	21835309	4.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	5491290	rs4702271	T	C	rs4702271	21835309	1.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	6767312	rs12520016	T	G	rs12520016	23548203	9.00E-07	Intermediate/Green eye color	0.42	[0.26-0.58] unit increase	3871 European ancestry individuals	European(3871)	ALL(3871)	EUR(3871)	ALL(3871)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12520016-G	Research Support, N.I.H., Extramural	T	NA
5	33951693	rs16891982	C	G	rs16891982	20585627	1.00E-12	eye color	0.84	NA	9,126 European ancestry individuals	European(9126)	ALL(9126)	EUR(9126)	ALL(9126)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	C	NA
5	107400505	rs288139	G	A	rs288139	23118974	1.00E-06	NA	0.21	[0.12-0.29] unit increase	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs288139-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	136953007	rs757157	T	C	rs757157	21835309	1.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	169272610	rs30079	C	T	rs30079	21835309	8.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	396321	rs12203592	C	T	rs12203592	20585627	2.00E-15	eye color	0.42	[NA] unit increase	9,126 European ancestry individuals	European(9126)	ALL(9126)	EUR(9126)	ALL(9126)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12203592-T	Research Support, Non-U.S. Gov't	C	IRF4
6	46807040	rs1059276	C	A	rs1059276	21835309	1.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	111848191	rs3851228	A	T	rs3851228	21835309	6.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	148781825	rs9399650	T	C	rs9399650	21835309	3.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	151572523	rs10499266	G	A	rs10499266	23118974	3.03E-05	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
7	1076010	rs2030958	G	T	rs2030958	21835309	4.90E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	1153141	rs12112166	T	C	rs12112166	21835309	9.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	4539599	rs7799050	A	C	rs7799050	23118974	4.04E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	20604449	rs2188866	C	T	rs2188866	23118974	9.69E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
7	83656800	rs10235789	T	C	rs10235789	21835309	3.00E-06	Furrows	0.09	[0.05-0.13] unit decrease	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	rs10235789-C	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	83656800	rs10235789	T	C	rs10235789	21835309	7.00E-11	Crypts	0.12	[0.08-0.16] unit increase	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	rs10235789-C	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	87492141	rs10216040	A	T	rs10216040	21835309	9.90E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	87513567	rs10225955	C	T	rs10225955	21835309	9.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	92437786	rs11974095	T	C	rs11974095	21835309	1.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	95081990	rs10225097	G	C	rs10225097	21835309	1.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	98225036	rs817771	A	G	rs817771	21835309	1.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	139786186	rs11972958	G	A	rs11972958	21835309	3.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
8	69580838	rs11989456	G	A	rs11989456	21835309	5.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
8	81467155	rs474402	G	C	rs474402	21835309	9.50E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
8	81733727	rs3907424	C	A	rs3907424	21835309	2.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
8	99008727	rs2513852	C	A	rs2513852	23118974	6.45E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
8	99428499	rs17370425	C	T	rs17370425	21835309	2.90E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
8	104121274	rs2515173	G	T	rs2515173	21835309	5.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
8	129117936	rs2720672	A	G	rs2720672	23118974	6.71E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
8	132353735	rs4596632	G	A	rs4596632	23118974	3.00E-06	NA	0.17	[0.098-0.236] unit increase	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs4596632-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
9	12672097	rs1408799	T	C	rs1408799	18488028	6.00E-17	NA	1.4	[1.25-1.57]	5,130 individuals	NOPOP(5130)	ALL(5130)	NOPOP(5130)	ALL(5130)	Blue vs. green eyes	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs1408799-C	Research Support, N.I.H., Intramural	T	NA
9	12672097	rs1408799	T	C	rs1408799	23548203	5.00E-07	Blue eye color	0.27	[0.17-0.37] unit decrease	3871 European ancestry individuals	European(3871)	ALL(3871)	EUR(3871)	ALL(3871)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs1408799-C	Research Support, N.I.H., Extramural	T	NA
9	14631836	rs2382492	G	T	rs2382492	21835309	1.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	19402041	rs10757054	G	A	rs10757054	21835309	7.80E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
10	2864447	rs7080882	G	A	rs7080882	23118974	1.57E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
10	28260543	rs12218330	A	G	rs12218330	21835309	1.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
10	117932193	rs11197567	G	A	rs11197567	23118974	3.99E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
11	1115911	rs10902095	T	C	rs10902095	21835309	3.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	2228952	rs7126629	C	A	rs7126629	21835309	1.80E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	3645345	rs10834648	G	A	rs10834648	21835309	3.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	9559481	rs12272194	T	C	rs12272194	21835309	8.70E-06	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	14508698	rs11023238	T	C	rs11023238	21835309	2.50E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	14798806	rs6486202	A	C	rs6486202	21835309	2.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	17107163	rs17560341	G	A	rs17560341	21835309	5.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	17267164	rs7108315	C	T	rs7108315	21835309	7.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	22686050	rs10833798	A	T	rs10833798	21835309	6.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	48535205	rs10838924	C	T	rs10838924	21835309	4.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	75860179	rs660981	C	A	rs660981	21835309	8.10E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	87829246	rs501234	G	A	rs501234	23118974	2.46E-04	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
11	89005253	rs1847134	A	C	rs1847134	20585627	1.00E-15	green eyes	1.58	NA	9,126 European ancestry individuals	European(9126)	ALL(9126)	EUR(9126)	ALL(9126)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs1847134-A	Research Support, Non-U.S. Gov't	A	TYR
11	89011046	rs1393350	G	A	rs1393350	17952075	3.00E-12	NA	1.52	[1.28-1.81]	2,986 individuals	NOPOP(2986)	ALL(2986)	NOPOP(2986)	ALL(2986)	Blue vs. green eyes	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs1393350-A	NA	G	TYR
11	89011046	rs1393350	G	A	rs1393350	20585627	3.00E-09	NA	0.28	[NA] unit decrease	9,126 European ancestry individuals	European(9126)	ALL(9126)	EUR(9126)	ALL(9126)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs1393350-A	Research Support, Non-U.S. Gov't	G	TYR
11	93767116	rs4753115	G	A	rs4753115	21835309	4.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	120012390	rs470411	G	C	rs470411	21835309	7.50E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	122932123	rs10892958	C	G	rs10892958	21835309	4.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	56032766	rs7978340	G	A	rs7978340	21835309	3.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	95928560	rs2197973	C	T	rs2197973	21835309	5.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	102162325	rs10492085	G	A	rs10492085	21835309	1.50E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	111833589	rs10774623	A	G	rs10774623	21835309	9.50E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	112062875	rs1544396	T	C	rs1544396	21835309	4.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	112228714	rs440	T	C	rs440	21835309	1.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	112246954	rs7296651	C	G	rs7296651	21835309	3.80E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	112490764	rs2339941	G	A,C,T	rs2339941	21835309	2.80E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
13	28506003	rs4769581	T	C	rs4769581	21835309	3.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
13	48640749	rs2104480	C	G	rs2104480	21835309	1.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
14	92763391	rs4900109	G	T	rs4900109	21835309	8.00E-21	Pigmented Ring	0.17	[0.13-0.21] unit increase	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	rs4900109-G	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
14	92773663	rs12896399	G	T	rs12896399	17952075	4.00E-38		2.06	[1.76-2.42]	2,986 individuals	NOPOP(2986)	ALL(2986)	NOPOP(2986)	ALL(2986)	Blue vs. green eyes	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12896399-T	NA	G	NA
14	92773663	rs12896399	G	T	rs12896399	20585627	1.00E-16	eye color	0.34	[NA] unit decrease	9,126 European ancestry individuals	European(9126)	ALL(9126)	EUR(9126)	ALL(9126)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12896399-T	Research Support, Non-U.S. Gov't	G	NA
14	92773663	rs12896399	G	T	rs12896399	20585627	2.00E-23	green eyes	1.73	NA	9,126 European ancestry individuals	European(9126)	ALL(9126)	EUR(9126)	ALL(9126)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12896399-G	Research Support, Non-U.S. Gov't	G	NA
14	92773663	rs12896399	G	T	rs12896399	23548203	3.00E-07	Intermediate/Green eye color	0.27	[0.17-0.37] unit decrease	3871 European ancestry individuals	European(3871)	ALL(3871)	EUR(3871)	ALL(3871)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12896399-G	Research Support, N.I.H., Extramural	G	NA
14	92773663	rs12896399	G	T	rs12896399	23548203	4.00E-11	Blue eye color	0.33	[0.23-0.43] unit increase	3871 European ancestry individuals	European(3871)	ALL(3871)	EUR(3871)	ALL(3871)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12896399-G	Research Support, N.I.H., Extramural	G	NA
15	27706279	rs6497269	G	A	rs6497269	18252221	2.80E-267	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	G
15	27776043	rs3097489	T	C	rs3097489	21835309	8.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	28185038	rs2594935	G	A	rs2594935	18252221	1.45E-10	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	A
15	28196821	rs7173419	T	C	rs7173419	23548203	1.00E-07	Brown eye color	0.33	[0.21-0.45] unit increase	3871 European ancestry individuals	European(3871)	ALL(3871)	EUR(3871)	ALL(3871)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs7173419-T	Research Support, N.I.H., Extramural	C	OCA2
15	28199853	rs728405	C	A	rs728405	18252221	3.75E-09	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	G
15	28272065	rs3794604	C	T	rs3794604	18252221	8.50E-12	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	G
15	28281765	rs4778232	C	T	rs4778232	18252221	2.47E-13	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	T
15	28282741	rs1448485	G	T	rs1448485	18252221	3.39E-08	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	A
15	28283689	rs8024968	C	T	rs8024968	18252221	1.48E-11	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	C
15	28294922	rs1597196	G	T	rs1597196	18252221	9.10E-18	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	T
15	28323770	rs7179994	A	G	rs7179994	18252221	5.35E-13	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	G
15	28335820	rs4778138	A	G	rs4778138	18252221	5.40E-211	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	G
15	28338713	rs4778241	A	C	rs4778241	18252221	3.66E-19	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	A
15	28344238	rs7495174	A	G	rs7495174	18252221	1.40E-239	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	G
15	28344238	rs7495174	A	G	rs7495174	23486544	1.45E-08	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Brown eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	NA	NA	NA	NA	Eye disease	NA	Research Support, Non-U.S. Gov't	G	OCA2
15	28344238	rs7495174	A	G	rs7495174	23486544	4.51E-09	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	G	OCA2
15	28356859	rs1129038	C	T	rs1129038	23486544	3.61E-31	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Brown eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	NA	NA	NA	NA	Eye disease	NA	Research Support, Non-U.S. Gov't	G	HERC2
15	28356859	rs1129038	C	T	rs1129038	23486544	4.99E-37	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	G	HERC2
15	28359258	rs12593929	G	A	rs12593929	23486544	1.01E-09	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	G	HERC2
15	28359258	rs12593929	G	A	rs12593929	23486544	1.94E-09	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Brown eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	NA	NA	NA	NA	Eye disease	NA	Research Support, Non-U.S. Gov't	G	HERC2
15	28365618	rs12913832	A	G	rs12913832	20463881	1.00E-300	RS123 cohort	NA	NA	5,951 Dutch individuals	Dutch(5951)	ALL(5951)	EUR(5951)	ALL(5951)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	28365618	rs12913832	A	G	rs12913832	20585627	1.00E-300	eye color	2.49	[NA] unit increase	9,126 European ancestry individuals	European(9126)	ALL(9126)	EUR(9126)	ALL(9126)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12913832-A	Research Support, Non-U.S. Gov't	A	HERC2
15	28365618	rs12913832	A	G	rs12913832	20585627	3.00E-52	green eyes	8.43	NA	9,126 European ancestry individuals	European(9126)	ALL(9126)	EUR(9126)	ALL(9126)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12913832-A	Research Support, Non-U.S. Gov't	A	HERC2
15	28365618	rs12913832	A	G	rs12913832	23486544	3.61E-31	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Brown eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	NA	NA	NA	NA	Eye disease	NA	Research Support, Non-U.S. Gov't	A	HERC2
15	28365618	rs12913832	A	G	rs12913832	23486544	4.99E-37	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	A	HERC2
15	28365618	rs12913832	A	G	rs12913832	23548203	1.00E-158	Blue eye color	2.84	[2.62-3.06] unit decrease	3871 European ancestry individuals	European(3871)	ALL(3871)	EUR(3871)	ALL(3871)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12913832-G	Research Support, N.I.H., Extramural	A	HERC2
15	28365618	rs12913832	A	G	rs12913832	23548203	1.00E-177	Brown eye color	2.82	[2.62-3.02] unit increase	3871 European ancestry individuals	European(3871)	ALL(3871)	EUR(3871)	ALL(3871)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs12913832-A	Research Support, N.I.H., Extramural	A	HERC2
15	28365733	rs7183877	C	A	rs7183877	18252221	6.18E-11	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	C
15	28374012	rs3935591	T	C	rs3935591	23486544	1.44E-13	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	A	HERC2
15	28374012	rs3935591	T	C	rs3935591	23486544	6.23E-12	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Brown eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	NA	NA	NA	NA	Eye disease	NA	Research Support, Non-U.S. Gov't	A	HERC2
15	28386626	rs11636232	C	T	rs11636232	23486544	1.28E-10	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	C	HERC2
15	28386626	rs11636232	C	T	rs11636232	23486544	4.27E-09	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Brown eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	NA	NA	NA	NA	Eye disease	NA	Research Support, Non-U.S. Gov't	C	HERC2
15	28440287	rs6497287	T	C	rs6497287	18252221	5.05E-15	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	T
15	28443658	rs8041209	G	T	rs8041209	18252221	6.60E-22	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	T
15	28488888	rs8028689	T	C	rs8028689	18252221	1.22E-21	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	C
15	28488888	rs8028689	T	C	rs8028689	23118974	1.11E-07	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
15	28494032	rs2240204	G	A	rs2240204	18252221	7.15E-11	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	C
15	28496195	rs6497292	A	G	rs6497292	18252221	8.16E-14	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	G
15	28510895	rs2240202	G	A	rs2240202	18252221	2.23E-22	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	C
15	28513364	rs916977	T	C	rs916977	18252221	1.00E-43	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	A
15	28513364	rs916977	T	C	rs916977	23486544	3.29E-16	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	A	HERC2
15	28513364	rs916977	T	C	rs916977	23486544	6.35E-14	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Brown eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	NA	NA	NA	NA	Eye disease	NA	Research Support, Non-U.S. Gov't	A	HERC2
15	28516084	rs8039195	C	T	rs8039195	18252221	1.78E-23	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	C
15	28516084	rs8039195	C	T	rs8039195	23118974	2.77E-18	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
15	28520506	rs16950979	A	G	rs16950979	18252221	7.02E-11	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	A
15	28522684	rs2346050	T	C	rs2346050	18252221	6.32E-19	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	G
15	28526228	rs16950987	G	A	rs16950987	18252221	8.28E-11	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	A
15	28526228	rs16950987	G	A	rs16950987	23118974	1.12E-08	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
15	28530182	rs1667394	C	T	rs1667394	17952075	1.00E-241		29.43	[21.47-40.35]	2,986 individuals	NOPOP(2986)	ALL(2986)	NOPOP(2986)	ALL(2986)	Blue vs. brown eyes	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs1667394-A	NA	G	HERC2
15	28530182	rs1667394	C	T	rs1667394	17952075	2.00E-53		6.74	[4.61-9.83]	2,986 individuals	NOPOP(2986)	ALL(2986)	NOPOP(2986)	ALL(2986)	Blue vs. green eyes	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs1667394-A	NA	G	HERC2
15	28530182	rs1667394	C	T	rs1667394	18252221	8.47E-31	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	G
15	28530182	rs1667394	C	T	rs1667394	23118974	2.00E-20	Eye color	0.35	[0.28-0.42] unit increase	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs1667394-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
15	28530182	rs1667394	C	T	rs1667394	23486544	4.92E-16	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	G	HERC2
15	28530182	rs1667394	C	T	rs1667394	23486544	7.95E-14	NA	NA	NA	710 individuals	NOPOP(710)	ALL(710)	NOPOP(710)	ALL(710)	Brown eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	NA	NA	NA	NA	Eye disease	NA	Research Support, Non-U.S. Gov't	G	HERC2
15	28530359	rs12592730	G	A	rs12592730	18252221	2.58E-22	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	G
15	28535266	rs1635168	A	C	rs1635168	18252221	1.48E-11	NA	NA	NA	1,406 individuals	NOPOP(1406)	ALL(1406)	NOPOP(1406)	ALL(1406)	Iris color	HPOID:0001100	Heterochromia iridis	DOID:240	iris disease	D007499	Iris Diseases	EFOID:0003949	eye color	Eye disease	NA	Research Support, Non-U.S. Gov't	Comparative Study	T
15	28535266	rs1635168	A	C	rs1635168	23118974	1.17E-09	NA	NA	NA	175 European ancestry individuals	European(175)	ALL(175)	EUR(175)	ALL(175)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
15	40681676	rs6492944	T	A	rs6492944	21835309	9.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	40707456	rs875767	C	T	rs875767	21835309	2.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	63915786	rs11630290	C	T	rs11630290	21835309	1.00E-06	Iris Nevi	0.09	[0.05-0.13] unit increase	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	rs11630290-C	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	74116224	rs1478558	G	A	rs1478558	21835309	1.20E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	74535158	rs11858661	C	T	rs11858661	21835309	7.50E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	90332639	rs16974181	C	G	rs16974181	21835309	6.20E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
16	69055675	rs251100	C	A	rs251100	21835309	2.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
16	69102989	rs12325454	T	C	rs12325454	21835309	9.50E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	19594008	rs2386142	A	G	rs2386142	21835309	6.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	27072463	rs4795456	G	A	rs4795456	21835309	8.50E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	27119524	rs12453504	C	A	rs12453504	21835309	6.90E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	27185827	rs2242345	C	T	rs2242345	21835309	4.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	43036260	rs7225162	C	T	rs7225162	21835309	3.50E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	49009532	rs1860443	C	G	rs1860443	21835309	2.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	65894542	rs6504550	A	G	rs6504550	21835309	7.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	66455904	rs1108683	T	A	rs1108683	21835309	5.30E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	79596811	rs9894429	C	T	rs9894429	20463881	9.00E-14	CHS1	0.12	[NA] % increase	5,951 Dutch individuals	Dutch(5951)	ALL(5951)	EUR(5951)	ALL(5951)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs9894429-T	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	80842251	rs3744159	G	A	rs3744159	21835309	5.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
18	12999964	rs12605081	A	G	rs12605081	21835309	9.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
18	13174963	rs17604778	C	T	rs17604778	21835309	6.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
18	18671098	rs8085504	G	A	rs8085504	21835309	5.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
19	17422833	rs971694	T	C	rs971694	21835309	2.70E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
19	35422808	rs10422961	C	T	rs10422961	21835309	3.00E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
19	35449760	rs2651080	G	C	rs2651080	21835309	3.20E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
19	36147315	rs7254601	A	G	rs7254601	21835309	2.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
19	47600601	rs8101091	A	G	rs8101091	21835309	4.20E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
19	48330297	rs11665715	C	T	rs11665715	21835309	7.30E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
19	49618778	rs1009213	A	G	rs1009213	21835309	8.60E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
19	55033973	rs8109847	G	T	rs8109847	21835309	2.80E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
20	60765422	rs6062130	C	T	rs6062130	21835309	1.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
21	28324568	rs233896	T	G	rs233896	21835309	7.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
21	38491095	rs1003719	A	G	rs1003719	20463881	2.00E-10	CHS1	0.1	[NA] % decrease	5,951 Dutch individuals	Dutch(5951)	ALL(5951)	EUR(5951)	ALL(5951)	Eye color	HPOID:0000478	Abnormality of the eye	DOID:240	iris disease	D003117	Color Vision Defects	EFOID:0003949	eye color	Eye disease	rs1003719-A	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
21	45721192	rs2236669	T	C	rs2236669	21835309	4.80E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
21	47431917	rs13047753	G	A	rs13047753	21835309	1.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
21	47442576	rs13046217	T	C	rs13046217	21835309	9.00E-05	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
22	20946302	rs165591	G	T	rs165591	21835309	2.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
22	31018646	rs2301955	C	T	rs2301955	21835309	3.10E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
22	42461918	rs2854827	G	A	rs2854827	21835309	4.90E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
22	42552253	rs742086	T	G	rs742086	21835309	3.40E-04	NA	NA	NA	2,121 European ancestry individuals	European(2121)	ALL(2121)	EUR(2121)	ALL(2121)	Iris characteristics	HPOID:0000525	Abnormality of the iris	DOID:240	iris disease	NA	NA	EFOID:0004731	eye measurement	Eye disease	NA	Twin Study	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0022078	mitomycin	D016685	1950/7/7	iris diseases	MESH:D007499	marker/mechanism	1454338

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)