PedAM
Pediatric Disease Annotations & Medicines
| intermediate coronary syndrome | ||||
| Disease ID | 1109 |
|---|---|
| Disease | intermediate coronary syndrome |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | (Waiting for update.) |
| Disease ID | 1109 |
|---|---|
| Disease | intermediate coronary syndrome |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:5) | |||||||||||||
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| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs4244285 | 23993903 | 5444 | PON1 | umls:C0002965 | BeFree | This study aimed to evaluate the impact of PON1 Q192R in parallel to that of CYP2C19*2 (rs4244285) on clopidogrel responsiveness in a cohort of Chinese patients with unstable angina pectoris. | 0.000542884 | 2013 | CYP2C19 | 10 | 94781859 | G | A,C |
| rs4244285 | 23993903 | 1557 | CYP2C19 | umls:C0002965 | BeFree | This study aimed to evaluate the impact of PON1 Q192R in parallel to that of CYP2C19*2 (rs4244285) on clopidogrel responsiveness in a cohort of Chinese patients with unstable angina pectoris. | 0.002909916 | 2013 | CYP2C19 | 10 | 94781859 | G | A,C |
| rs662 | 23993903 | 5444 | PON1 | umls:C0002965 | BeFree | This study aimed to evaluate the impact of PON1 Q192R in parallel to that of CYP2C19*2 (rs4244285) on clopidogrel responsiveness in a cohort of Chinese patients with unstable angina pectoris. | 0.000542884 | 2013 | PON1 | 7 | 95308134 | T | C |
| rs662 | 23993903 | 1557 | CYP2C19 | umls:C0002965 | BeFree | This study aimed to evaluate the impact of PON1 Q192R in parallel to that of CYP2C19*2 (rs4244285) on clopidogrel responsiveness in a cohort of Chinese patients with unstable angina pectoris. | 0.002909916 | 2013 | PON1 | 7 | 95308134 | T | C |
| rs662 | 22368149 | 5444 | PON1 | umls:C0002965 | BeFree | Effect of PON1 Q192R genetic polymorphism on clopidogrel efficacy and cardiovascular events in the Clopidogrel in the Unstable Angina to Prevent Recurrent Events trial and the Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events. | 0.000542884 | 2012 | PON1 | 7 | 95308134 | T | C |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:4) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0002965 | acetylcysteine | D000111 | 616-91-1 | angina, unstable | MESH:D000789 | therapeutic | 3127076 | ||
| C0002965 | diltiazem | D004110 | 42399-41-7 | angina, unstable | MESH:D000789 | therapeutic | 3385716 | ||
| C0002965 | fluorouracil | D005472 | 51-21-8 | angina, unstable | MESH:D000789 | marker/mechanism | 10874764 | ||
| C0002965 | tretinoin | D014212 | 302-79-4 | angina, unstable | MESH:D000789 | marker/mechanism | 10025910 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |