PedAM
Pediatric Disease Annotations & Medicines
| influenza | ||||
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:8) | |||||||||||||
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| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs113488022 | 22887810 | 673 | BRAF | umls:C0021400 | BeFree | However, a subset of AUS/FLUS cases with the V600E BRAF mutation appeared to represent sampling variability of the classic or tall cell variants of PTC. | 0.001357209 | 2013 | BRAF | 7 | 140753336 | A | T,G,C |
| rs113488022 | 24261392 | 673 | BRAF | umls:C0021400 | BeFree | We also investigated the value of ultrasound features that predict malignancy and BRAF(V600E) mutation analysis and suggest strategies for the management of AUS/FLUS nodules. | 0.001357209 | 2014 | BRAF | 7 | 140753336 | A | T,G,C |
| rs12252 | 25942469 | 10331 | B3GNT3 | umls:C0021400 | BeFree | Interferon-Inducible Transmembrane Protein 3 Genetic Variant rs12252 and Influenza Susceptibility and Severity: A Meta-Analysis. | 0.000814326 | 2015 | IFITM3 | 11 | 320772 | A | G |
| rs12252 | NA | 10410 | IFITM3 | umls:C0021400 | CLINVAR | NA | 0.242442977 | NA | IFITM3 | 11 | 320772 | A | G |
| rs12252 | 25314048 | 10410 | IFITM3 | umls:C0021400 | BeFree | IFITM3 polymorphism rs12252-C restricts influenza A viruses. | 0.242442977 | 2014 | IFITM3 | 11 | 320772 | A | G |
| rs12252 | 23361009 | 10410 | IFITM3 | umls:C0021400 | BeFree | Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals. | 0.242442977 | 2013 | IFITM3 | 11 | 320772 | A | G |
| rs12252 | 25942469 | 10410 | IFITM3 | umls:C0021400 | BeFree | Our meta-analysis suggests a significant association between a minor IFITM3 allele (SNP rs12252-C) with severe influenza susceptibility, but not in mild influenza subjects, in both UK Caucasians and Han Chinese population. | 0.242442977 | 2015 | IFITM3 | 11 | 320772 | A | G |
| rs2229291 | 21277129 | 1376 | CPT2 | umls:C0021400 | BeFree | Recent studies suggested that the thermolabile phenotype of carnitine palmitoyltransferase II (CPT II) variation [F352C] was closely related to the pathomechanism of influenza-associated encephalopathy (IAE) in Japanese, causing mitochondrial ATP utilization failure during periods of high fever, resulting in brain edema. | 0.001628651 | 2012 | CPT2 | 1 | 53210729 | T | G |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:1) | |||||||||||||||||||||||||||||
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| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 1 | 207494416 | rs2564978 | T | C | rs2564978 | 22693232 | 0.0005 | NA | NA | NA | 51 Chinese individuals | Chinese(51) | ALL(51) | ASN(51) | ALL(51) | H1N1 influenza A virus infection | HPOID:0004429 | Recurrent viral infections | DOID:8469 | influenza | NA | NA | NA | NA | Influenza | NA | Research Support, Non-U.S. Gov't | C | CD55 |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:5) | |||||||||
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| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0021400 | azithromycin | D017963 | 83905-01-5 | influenza, human | MESH:D007251 | therapeutic | 8701248 | ||
| C0021400 | masoprocol | D009637 | - | influenza, human | MESH:D007251 | therapeutic | 18473937 | ||
| C0021400 | oseltamivir | D053139 | - | influenza, human | MESH:D007251 | therapeutic | 11043756 | ||
| C0021400 | rimantadine | D012299 | 13392-28-4 | influenza, human | MESH:D007251 | therapeutic | 10826462 | ||
| C0021400 | vitamin e | D014810 | 1406-18-4 | influenza, human | MESH:D007251 | therapeutic | 16624496 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |