PedAM

Pediatric Disease Annotations & Medicines


	impulse control disorder

Disease ID	1306
Disease	impulse control disorder
Definition	Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.
Synonym	control disorder impulse disorders, impulse control disruptive, impulse control, and conduct disorders disruptive, impulse control, and conduct disorders [disease/finding] impulse control dis impulse control dis nos impulse control disorder (disorder) impulse control disorder nos impulse control disorder nos (disorder) impulse control disorder, nos impulse control disorder, unspecified impulse control disorder, unspecified (disorder) impulse control disorders impulse-control disorder impulse-control disorders
DOID	DOID:10937
UMLS	C0021122
MeSH	D007174
SNOMED-CT	SNOMEDCT_US_2016_09_01:66347000
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:17) C0030567 \| parkinson's disease \| 44 C0030567 \| parkinson disease \| 11 C0030662 \| pathological gambling \| 2 C0011570 \| depression \| 2 C0003467 \| anxiety \| 1 C0005586 \| bipolar disorder \| 1 C0751772 \| rem sleep behavior disorder \| 1 C0013384 \| dyskinesias \| 1 C0035258 \| restless legs \| 1 C0013421 \| dystonia \| 1 C0003469 \| anxiety disorder \| 1 C0004943 \| behcet's disease \| 1 C0003469 \| anxiety disorders \| 1 C0033375 \| prolactinomas \| 1 C1389280 \| basal ganglia calcification \| 1 C0035258 \| restless legs syndrome \| 1 C0338451 \| frontotemporal dementia \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:3) DRD2 \| 1813 \| CTD_human FOSB \| 2354 \| CTD_human DRD3 \| 1814 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:7) 1812 \| DRD1 \| infer 1813 \| DRD2 \| infer 1814 \| DRD3 \| infer 1815 \| DRD4 \| infer 1816 \| DRD5 \| infer 3356 \| HTR2A \| infer 6532 \| SLC6A4 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:89) 1815 \| DRD4 \| DISEASES 1512 \| CTSH \| DISEASES 4669 \| NAGLU \| DISEASES 116449 \| CLNK \| DISEASES 11211 \| FZD10 \| DISEASES 5754 \| PTK7 \| DISEASES 58512 \| DLGAP3 \| DISEASES 3218 \| HOXB8 \| DISEASES 7291 \| TWIST1 \| DISEASES 5552 \| SRGN \| DISEASES 2354 \| FOSB \| DISEASES 51540 \| SCLY \| DISEASES 29113 \| C6orf15 \| DISEASES 9360 \| PPIG \| DISEASES 5687 \| PSMA6 \| DISEASES 6532 \| SLC6A4 \| DISEASES 10049 \| DNAJB6 \| DISEASES 4969 \| OGN \| DISEASES 2033 \| EP300 \| DISEASES 30846 \| EHD2 \| DISEASES 492 \| ATP2B3 \| DISEASES 64083 \| GOLPH3 \| DISEASES 10058 \| ABCB6 \| DISEASES 55749 \| CCAR1 \| DISEASES 6531 \| SLC6A3 \| DISEASES 3358 \| HTR2C \| DISEASES 5047 \| PAEP \| DISEASES 5531 \| PPP4C \| DISEASES 2904 \| GRIN2B \| DISEASES 4154 \| MBNL1 \| DISEASES 3973 \| LHCGR \| DISEASES 256471 \| MFSD8 \| DISEASES 89832 \| CHRFAM7A \| DISEASES 6632 \| SNRPD1 \| DISEASES 4054 \| LTBP3 \| DISEASES 116844 \| LRG1 \| DISEASES 9482 \| STX8 \| DISEASES 1816 \| DRD5 \| DISEASES 255239 \| ANKK1 \| DISEASES 157570 \| ESCO2 \| DISEASES 3642 \| INSM1 \| DISEASES 6448 \| SGSH \| DISEASES 3350 \| HTR1A \| DISEASES 2744 \| GLS \| DISEASES 4026 \| LPP \| DISEASES 4691 \| NCL \| DISEASES 8607 \| RUVBL1 \| DISEASES 23017 \| FAIM2 \| DISEASES 5663 \| PSEN1 \| DISEASES 23400 \| ATP13A2 \| DISEASES 1812 \| DRD1 \| DISEASES 9735 \| KNTC1 \| DISEASES 57142 \| RTN4 \| DISEASES 3363 \| HTR7 \| DISEASES 23583 \| SMUG1 \| DISEASES 4128 \| MAOA \| DISEASES 10019 \| SH2B3 \| DISEASES 2879 \| GPX4 \| DISEASES 2555 \| GABRA2 \| DISEASES 8936 \| WASF1 \| DISEASES 23230 \| VPS13A \| DISEASES 170482 \| CLEC4C \| DISEASES 1002 \| CDH4 \| DISEASES 1312 \| COMT \| DISEASES 1813 \| DRD2 \| DISEASES 153 \| ADRB1 \| DISEASES 1081 \| CGA \| DISEASES 9446 \| GSTO1 \| DISEASES 4534 \| MTM1 \| DISEASES 5832 \| ALDH18A1 \| DISEASES 2902 \| GRIN1 \| DISEASES 5453 \| POU3F1 \| DISEASES 114798 \| SLITRK1 \| DISEASES 4129 \| MAOB \| DISEASES 3356 \| HTR2A \| DISEASES 138050 \| HGSNAT \| DISEASES 8544 \| PIR \| DISEASES 2618 \| GART \| DISEASES 7436 \| VLDLR \| DISEASES 1814 \| DRD3 \| DISEASES 9467 \| SH3BP5 \| DISEASES 4501 \| MT1X \| DISEASES 152 \| ADRA2C \| DISEASES 10163 \| WASF2 \| DISEASES 57506 \| MAVS \| DISEASES 2593 \| GAMT \| DISEASES 1139 \| CHRNA7 \| DISEASES 627 \| BDNF \| DISEASES 488 \| ATP2A2 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1306
Disease	impulse control disorder
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:10) HP:0000716 \| Depression \| 2 HP:0002135 \| Basal ganglia calcification \| 1 HP:0012167 \| Trichotillomania \| 1 HP:0012452 \| Restless legs \| 1 HP:0007302 \| Bipolar disorder \| 1 HP:0002145 \| Frontotemporal dementia \| 1 HP:0100022 \| Movement disorder \| 1 HP:0001300 \| Parkinsonism \| 1 HP:0000739 \| Anxiety \| 1 HP:0001332 \| Dystonia \| 1

Disease ID	1306
Disease	impulse control disorder
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
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All Snps(Total Genotypes:0)
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GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
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Mapped by lexical matching(Total Items:0)
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Mapped by homologous gene(Total Items:0)
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Chemical(Total Drugs:17)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0021122	amitriptyline	D000639	50-48-6	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	6458665
C0021122	amphetamine	D000661	300-62-9	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	19784636
C0021122	citalopram	D015283	59729-33-8	disruptive, impulse control, and conduct disorders	MESH:D007174	therapeutic	12014784
C0021122	clonidine	D003000	4205-90-7	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	1125640
C0021122	clonidine	D003000	4205-90-7	disruptive, impulse control, and conduct disorders	MESH:D007174	therapeutic	18280681
C0021122	clozapine	D003024	5786-21-0	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	1527237
C0021122	clozapine	D003024	5786-21-0	disruptive, impulse control, and conduct disorders	MESH:D007174	therapeutic	11728832
C0021122	doxapram	D004315	309-29-5	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	964272
C0021122	fluoxetine	D005473	54910-89-3	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	25369145
C0021122	fluvoxamine	D016666	54739-18-3	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	12680750
C0021122	imipramine	D007099	50-49-7	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	6458665
C0021122	imipramine	D007099	50-49-7	disruptive, impulse control, and conduct disorders	MESH:D007174	therapeutic	6251483
C0021122	methylphenidate	D008774	113-45-1	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	11392335
C0021122	pramipexole	C061333	-	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	20457959
C0021122	ropinirole	C046649	91374-21-9	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	20447020
C0021122	theophylline	D013806	58-55-9	disruptive, impulse control, and conduct disorders	MESH:D007174	marker/mechanism	6093179
C0021122	valproic acid	D014635	99-66-1	disruptive, impulse control, and conduct disorders	MESH:D007174	therapeutic	17201610

FDA approved drug and dosage information(Total Drugs:0)
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FDA labeling changes(Total Drugs:0)
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