PedAM
Pediatric Disease Annotations & Medicines
| il13 gene | ||||
| Disease ID | 1032 |
|---|---|
| Disease | il13 gene |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:23) C0004096 | asthma | 95 C0014457 | eosinophilia | 18 C0002111 | allergy | 17 C0231918 | nasal symptoms | 10 C0009763 | conjunctivitis | 10 C0085129 | bronchial hyperreactivity | 7 C0334108 | polyposis | 6 C0422833 | ent symptoms | 5 C0037199 | sinusitis | 5 C0155877 | allergic asthma | 4 C0004096 | bronchial asthma | 4 C0027424 | nasal congestion | 3 C0009450 | infection | 2 C0021311 | infections | 2 C0026635 | mouth breathing | 2 C0035243 | respiratory infection | 2 C0085129 | bronchial hyperresponsiveness | 2 C1260880 | rhinorrhea | 1 C0847614 | nasal allergy | 1 C0149512 | acute sinusitis | 1 C0001883 | airway obstruction | 1 C0022073 | iridocyclitis | 1 C1260880 | rhinorrhoea | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:5) | |||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chr | Pos | SNP_Id | RefGene | EnsemblGene | ENCODE_Factor | ENCODE_TFBS | Chromosome_interaction | GTEx_eQTL | SNP_TFBS_affinity_GWAS3D | SNP_miRNA_target_affinity_PolymiRTS | SNP_splicing_effect_Skippy | SNP_splicing_effect_MutPred_Splice | SNP_ns_protein_effect_dbNSFP | SNP_syn_effect_Silva | SNP_phosphorylation_effect_PhosSNP | PhastCons_score | PhyloP_score | GERP++_RS | Segway_state | Ancestral_allele | ESP_AF | ESP_AFR | ESP_AFR | ESP_EUR | TG_ASN | TG_AMR | TG_AFR | TG_EUR | Type | Consequence | bStatistic | EncH3K27Ac | EncH3K4Me1 | EncH3K4Me3 | EncNucleo | OMIM | Clinvar |
| 1 | 19402390 | rs10158468 | NM_020765,UBR4 | ENST00000429347,ENSG00000127481 | ENST00000375217,ENSG00000127481 | ENST00000375226,ENSG00000127481 | ENST00000375267,ENSG00000127481 | ENST00000375254,ENSG00000127481 | ENST00000375225,ENSG00000127481 | ENST00000375224,ENSG00000127481 | ENST00000459947,ENSG00000127481 | ENST00000486515,ENSG00000127481 | MCV-1 | NA | chr1,19400001,19410000,chr1,19480001,19490000,28,Hi-C | chr1,19400001,19410000,chr3,20060001,20070000,30,Hi-C | chr1,19400001,19410000,chr1,19070001,19080000,5,Hi-C | chr1,19400001,19410000,chr10,123070001,123080000,5,Hi-C | chr1,19400001,19410000,chr1,19200001,19210000,7,Hi-C | chr1,19400001,19410000,chr3,154190001,154200000,10,Hi-C | chr1,19400001,19410000,chr12,84080001,84090000,6,Hi-C | NA | LM217,5.8887 | HMG-IY,1.3806 | ACTAYRNNNCCCR,1.9517 | v-Myb,1.3711 | c-Myb,3.2344 | NA | NA | NA | NA | NA | NA | 0.000 | -0.264 | -1.55 | TF1 |
| 1 | 19405237 | rs2146866 | NM_020765,UBR4 | ENST00000429347,ENSG00000127481 | ENST00000375217,ENSG00000127481 | ENST00000375226,ENSG00000127481 | ENST00000375267,ENSG00000127481 | ENST00000375254,ENSG00000127481 | ENST00000375225,ENSG00000127481 | ENST00000375224,ENSG00000127481 | ENST00000459947,ENSG00000127481 | ENST00000486515,ENSG00000127481 | TFP.CTCF | MCV-4 | NA | chr1,19400001,19410000,chr1,19480001,19490000,28,Hi-C | chr1,19400001,19410000,chr3,20060001,20070000,30,Hi-C | chr1,19400001,19410000,chr1,19070001,19080000,5,Hi-C | chr1,19400001,19410000,chr10,123070001,123080000,5,Hi-C | chr1,19400001,19410000,chr1,19200001,19210000,7,Hi-C | chr1,19400001,19410000,chr3,154190001,154200000,10,Hi-C | chr1,19400001,19410000,chr12,84080001,84090000,6,Hi-C | NA | NA | NA | NA | NA | NA | NA | NA | 0.091 | 1.342 | 4.2 | GE2 | A | NA | NA |
| 1 | 19437923 | rs12740975 | NM_020765,UBR4 | ENST00000429347,ENSG00000127481 | ENST00000375217,ENSG00000127481 | ENST00000375226,ENSG00000127481 | ENST00000375267,ENSG00000127481 | ENST00000375254,ENSG00000127481 | ENST00000494503,ENSG00000127481 | ENST00000466969,ENSG00000127481 | ENST00000375218,ENSG00000127481 | NA | NA | chr1,19430001,19440000,chr1,19470001,19480000,28,Hi-C | chr1,19430001,19440000,chr1,19450001,19460000,35,Hi-C | chr1,19430001,19440000,chr1,19460001,19470000,37,Hi-C | chr1,19430001,19440000,chr17,78160001,78170000,4,Hi-C | chr1,19430001,19440000,chr2,241990001,242000000,5,Hi-C | NA | LM47,1.3251 | LM130,3.4153 | FOXC1,1.7025 | CAGNWMCNNNGAC,1.9773 | at_AC_acceptor,1.2782 | NA | NA | NA | NA | NA | NA | 0.000 | -2.073 | -5.05 | GE2 | G | NA | NA |
| 1 | 19464773 | rs2274001 | NM_020765,UBR4 | ENST00000429347,ENSG00000127481 | ENST00000375217,ENSG00000127481 | ENST00000375226,ENSG00000127481 | ENST00000375267,ENSG00000127481 | ENST00000375254,ENSG00000127481 | ENST00000425413,ENSG00000127481 | ENST00000417040,ENSG00000127481 | MCV-1 | NA | chr1,19460001,19470000,chr1,19500001,19510000,25,Hi-C | chr1,19460001,19470000,chr1,19410001,19420000,28,Hi-C | chr1,19460001,19470000,chr1,19490001,19500000,29,Hi-C | chr1,19460001,19470000,chr1,19440001,19450000,32,Hi-C | chr1,19460001,19470000,chr1,19430001,19440000,37,Hi-C | NA | LM2,1.8049 | LM33,4.5693 | LM43,3.3406 | LM44,4.636 | LM49,2.3062 | NA | NA | NA | NA | NA | NA | 0.000 | -0.429 | -3.99 | GE2 | T | NA | NA | NA |
| 1 | 19500551 | rs1009806 | NM_020765,UBR4 | ENST00000429347,ENSG00000127481 | ENST00000375217,ENSG00000127481 | ENST00000375226,ENSG00000127481 | ENST00000375267,ENSG00000127481 | ENST00000375254,ENSG00000127481 | ENST00000419533,ENSG00000127481 | NA | NA | chr1,19500001,19510000,chr1,19460001,19470000,25,Hi-C | chr1,19500001,19510000,chr1,19480001,19490000,30,Hi-C | chr1,19500001,19510000,chr1,20000001,20010000,6,Hi-C | NA | LM54,2.0459 | LM77,1.9979 | LM110,1.6846 | LM119,2.2511 | LM151,1.5055 | NA | NA | NA | NA | NA | NA | 0.000 | -1.045 | -6.07 | GE1 | T | NA | NA | NA | NA | NA | NA |
GWASdb Snp Trait(Total Genotypes:18) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 1 | 17216331 | rs6586513 | C | A | rs6586513 | 22036096 | 4.00E-06 | NA | 1.24 | [1.13-1.36] | 3,933 European ancestry cases; 8,965 European ancestry controls | European(12898) | ALL(12898) | EUR(12898) | ALL(12898) | Allergic rhinitis | HPOID:0003193 | Allergic rhinitis | DOID:4481 | allergic rhinitis | D012221 | Rhinitis, Allergic, Perennial | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs6586513-C | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 1 | 51859242 | rs6673480 | C | T | rs6673480 | 22036096 | 2.00E-06 | NA | 1.35 | [1.19-1.52] | 2,315 Caucasian cases; 10,032 Caucasian controls | Caucasian(12347) | ALL(12347) | EUR(12347) | ALL(12347) | IgE grass sensitization | HPOID:0010701 | Abnormal immunoglobulin level | DOID:4481 | allergic rhinitis | D006969 | Hypersensitivity, Immediate | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs6673480-T | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 1 | 179071756 | rs1325195 | G | A | rs1325195 | 22036096 | 5.00E-06 | NA | 1.17 | [1.10-1.26] | 2,315 Caucasian cases; 10,032 Caucasian controls | Caucasian(12347) | ALL(12347) | EUR(12347) | ALL(12347) | IgE grass sensitization | HPOID:0010701 | Abnormal immunoglobulin level | DOID:4481 | allergic rhinitis | D006969 | Hypersensitivity, Immediate | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs1325195-A | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 3 | 132727903 | rs7617456 | G | A | rs7617456 | 22036096 | 3.00E-06 | NA | 1.18 | [1.10-1.26] | 2,315 Caucasian cases; 10,032 Caucasian controls | Caucasian(12347) | ALL(12347) | EUR(12347) | ALL(12347) | IgE grass sensitization | HPOID:0010701 | Abnormal immunoglobulin level | DOID:4481 | allergic rhinitis | D006969 | Hypersensitivity, Immediate | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs7617456-G | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 4 | 123373133 | rs2069772 | T | C | rs2069772 | 22036096 | 1.00E-06 | NA | 1.19 | [1.11-1.28] | 2,315 Caucasian cases; 10,032 Caucasian controls | Caucasian(12347) | ALL(12347) | EUR(12347) | ALL(12347) | IgE grass sensitization | HPOID:0010701 | Abnormal immunoglobulin level | DOID:4481 | allergic rhinitis | D006969 | Hypersensitivity, Immediate | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs2069772-C | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 5 | 13740976 | rs6554809 | C | T | rs6554809 | 22036096 | 3.00E-06 | NA | 1.29 | [1.16-1.43] | 2,315 Caucasian cases; 10,032 Caucasian controls | Caucasian(12347) | ALL(12347) | EUR(12347) | ALL(12347) | IgE grass sensitization | HPOID:0010701 | Abnormal immunoglobulin level | DOID:4481 | allergic rhinitis | D006969 | Hypersensitivity, Immediate | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs6554809-C | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 5 | 110146446 | rs17513503 | C | G | rs17513503 | 22036096 | 1.00E-08 | NA | 1.39 | [1.24-1.56] | 2,315 Caucasian cases; 10,032 Caucasian controls | Caucasian(12347) | ALL(12347) | EUR(12347) | ALL(12347) | IgE grass sensitization | HPOID:0010701 | Abnormal immunoglobulin level | DOID:4481 | allergic rhinitis | D006969 | Hypersensitivity, Immediate | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs17513503-G | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 5 | 110146446 | rs17513503 | C | G | rs17513503 | 22036096 | 7.00E-07 | NA | 1.28 | [1.16-1.41] | 3,933 European ancestry cases; 8,965 European ancestry controls | European(12898) | ALL(12898) | EUR(12898) | ALL(12898) | Allergic rhinitis | HPOID:0003193 | Allergic rhinitis | DOID:4481 | allergic rhinitis | D012221 | Rhinitis, Allergic, Perennial | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs17513503-G | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 5 | 110408002 | rs1898671 | C | T | rs1898671 | 22036096 | 5.00E-06 | NA | 1.15 | [1.08-1.22] | 3,933 European ancestry cases; 8,965 European ancestry controls | European(12898) | ALL(12898) | EUR(12898) | ALL(12898) | Allergic rhinitis | HPOID:0003193 | Allergic rhinitis | DOID:4481 | allergic rhinitis | D012221 | Rhinitis, Allergic, Perennial | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs1898671-T | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 5 | 115975656 | rs6898653 | A | G | rs6898653 | 22036096 | 1.00E-06 | NA | 1.23 | [1.13-1.34] | 3,933 European ancestry cases; 8,965 European ancestry controls | European(12898) | ALL(12898) | EUR(12898) | ALL(12898) | Allergic rhinitis | HPOID:0003193 | Allergic rhinitis | DOID:4481 | allergic rhinitis | D012221 | Rhinitis, Allergic, Perennial | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs6898653-G | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 6 | 32658079 | rs7775228 | T | C | rs7775228 | 22036096 | 2.00E-09 | NA | 1.33 | [1.21-1.45] | 2,315 Caucasian cases; 10,032 Caucasian controls | Caucasian(12347) | ALL(12347) | EUR(12347) | ALL(12347) | IgE grass sensitization | HPOID:0010701 | Abnormal immunoglobulin level | DOID:4481 | allergic rhinitis | D006969 | Hypersensitivity, Immediate | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs7775228-C | Meta-Analysis | Research Support, Non-U.S. Gov't | T,C |
| 7 | 42264679 | rs4724100 | T | C | rs4724100 | 22036096 | 2.00E-06 | NA | 1.14 | [1.08-1.21] | 3,933 European ancestry cases; 8,965 European ancestry controls | European(12898) | ALL(12898) | EUR(12898) | ALL(12898) | Allergic rhinitis | HPOID:0003193 | Allergic rhinitis | DOID:4481 | allergic rhinitis | D012221 | Rhinitis, Allergic, Perennial | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs4724100-C | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 11 | 76299194 | rs2155219 | G | T | rs2155219 | 22036096 | 1.00E-08 | NA | 1.22 | [1.14-1.31] | 2,315 Caucasian cases; 10,032 Caucasian controls | Caucasian(12347) | ALL(12347) | EUR(12347) | ALL(12347) | IgE grass sensitization | HPOID:0010701 | Abnormal immunoglobulin level | DOID:4481 | allergic rhinitis | D006969 | Hypersensitivity, Immediate | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs2155219-T | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 11 | 76299194 | rs2155219 | G | T | rs2155219 | 22036096 | 4.00E-08 | NA | 1.17 | [1.11-1.24] | 3,933 European ancestry cases; 8,965 European ancestry controls | European(12898) | ALL(12898) | EUR(12898) | ALL(12898) | Allergic rhinitis | HPOID:0003193 | Allergic rhinitis | DOID:4481 | allergic rhinitis | D012221 | Rhinitis, Allergic, Perennial | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs2155219-T | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 14 | 60683430 | rs216518 | C | A | rs216518 | 22036096 | 2.00E-06 | NA | 1.21 | [1.12-1.31] | 3,933 European ancestry cases; 8,965 European ancestry controls | European(12898) | ALL(12898) | EUR(12898) | ALL(12898) | Allergic rhinitis | HPOID:0003193 | Allergic rhinitis | DOID:4481 | allergic rhinitis | D012221 | Rhinitis, Allergic, Perennial | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs216518-A | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 16 | 9399724 | rs631208 | A | G | rs631208 | 22036096 | 2.00E-06 | NA | 1.18 | [1.10-1.26] | 2,315 Caucasian cases; 10,032 Caucasian controls | Caucasian(12347) | ALL(12347) | EUR(12347) | ALL(12347) | IgE grass sensitization | HPOID:0010701 | Abnormal immunoglobulin level | DOID:4481 | allergic rhinitis | D006969 | Hypersensitivity, Immediate | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs631208-A | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 16 | 11158885 | rs887864 | G | A | rs887864 | 22036096 | 1.00E-06 | NA | 1.16 | [1.09-1.23] | 3,933 European ancestry cases; 8,965 European ancestry controls | European(12898) | ALL(12898) | EUR(12898) | ALL(12898) | Allergic rhinitis | HPOID:0003193 | Allergic rhinitis | DOID:4481 | allergic rhinitis | D012221 | Rhinitis, Allergic, Perennial | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs887864-A | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 20 | 25206654 | rs1044573 | A | G | rs1044573 | 22036096 | 1.00E-06 | NA | 1.15 | [1.09-1.21] | 3,933 European ancestry cases; 8,965 European ancestry controls | European(12898) | ALL(12898) | EUR(12898) | ALL(12898) | Allergic rhinitis | HPOID:0003193 | Allergic rhinitis | DOID:4481 | allergic rhinitis | D012221 | Rhinitis, Allergic, Perennial | EFOID:0003956 | seasonal allergic rhinitis | Atopic rhinitis | rs1044573-A | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
Chemical(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |