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Pediatric Disease Annotations & Medicines



   hyperostosis
  

Disease ID 1791
Disease hyperostosis
Definition
Increase in the mass of bone per unit volume.
Synonym
bone hypertrophies
bone hypertrophy
bone overgrowth
bony overgrowth
hyperostoses
hyperostosis [disease/finding]
hyperostosis, nos
hypertrophies, bone
hypertrophy of bone
hypertrophy of bone (disorder)
hypertrophy of bone (morphologic abnormality)
hypertrophy of bone, nos
hypertrophy, bone
DOID
UMLS
C0020492
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:27)
C0025286  |  meningiomas  |  3
C0025286  |  meningioma  |  3
C0029443  |  osteomyelitis  |  2
C0936248  |  chondroma  |  1
C1956089  |  osteophytes  |  1
C0085681  |  hyperphosphatemia  |  1
C0442874  |  neuropathy  |  1
C0030354  |  papilloma  |  1
C0037274  |  dermatosis  |  1
C0029454  |  osteopetrosis  |  1
C0005940  |  osteopathy  |  1
C0019829  |  hodgkin's lymphoma  |  1
C0206721  |  inverted papilloma  |  1
C0035579  |  rickets  |  1
C0085261  |  proteus syndrome  |  1
C0024299  |  lymphoma  |  1
C0038013  |  ankylosing spondylitis  |  1
C0281784  |  benign meningiomas  |  1
C0023798  |  lipoma  |  1
C0011847  |  diabetes  |  1
C0029132  |  optic neuropathy  |  1
C0005940  |  bone disease  |  1
C0020498  |  forestier disease  |  1
C0003864  |  arthritis  |  1
C0003872  |  psoriatic arthritis  |  1
C1956089  |  osteophyte  |  1
C0349604  |  intracranial meningioma  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:7)
EXT1  |  2131  |  UniProtKB-KW;GHR
SQSTM1  |  8878  |  GHR
TNFRSF11A  |  8792  |  GHR
TNFRSF11B  |  4982  |  GHR
SOST  |  50964  |  GHR
EXT2  |  2132  |  UniProtKB-KW;GHR
PTH  |  5741  |  CTD_human
Inferring Gene(Waiting for update.)
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:201)
11345  |  GABARAPL2  |  DISEASES
28962  |  OSTM1  |  DISEASES
6820  |  SULT2B1  |  DISEASES
8646  |  CHRD  |  DISEASES
6576  |  SLC25A1  |  DISEASES
79890  |  RIN3  |  DISEASES
54  |  ACP5  |  DISEASES
2137  |  EXTL3  |  DISEASES
8797  |  TNFRSF10A  |  DISEASES
7040  |  TGFB1  |  DISEASES
51510  |  CHMP5  |  DISEASES
1277  |  COL1A1  |  DISEASES
3381  |  IBSP  |  DISEASES
1075  |  CTSC  |  DISEASES
4256  |  MGP  |  DISEASES
6678  |  SPARC  |  DISEASES
51146  |  A4GNT  |  DISEASES
8074  |  FGF23  |  DISEASES
63923  |  TNN  |  DISEASES
8600  |  TNFSF11  |  DISEASES
23435  |  TARDBP  |  DISEASES
652  |  BMP4  |  DISEASES
5732  |  PTGER2  |  DISEASES
53947  |  A4GALT  |  DISEASES
79977  |  GRHL2  |  DISEASES
26290  |  GALNT8  |  DISEASES
78992  |  YIPF2  |  DISEASES
1401  |  CRP  |  DISEASES
2012  |  EMP1  |  DISEASES
9958  |  USP15  |  DISEASES
1593  |  CYP27A1  |  DISEASES
3569  |  IL6  |  DISEASES
11227  |  GALNT5  |  DISEASES
3557  |  IL1RN  |  DISEASES
26525  |  IL36RN  |  DISEASES
5037  |  PEBP1  |  DISEASES
4040  |  LRP6  |  DISEASES
9663  |  LPIN2  |  DISEASES
88455  |  ANKRD13A  |  DISEASES
7011  |  TEP1  |  DISEASES
10133  |  OPTN  |  DISEASES
7353  |  UFD1L  |  DISEASES
3553  |  IL1B  |  DISEASES
9917  |  FAM20B  |  DISEASES
26511  |  CHIC2  |  DISEASES
6883  |  TAF12  |  DISEASES
3299  |  HSF4  |  DISEASES
1950  |  EGF  |  DISEASES
7375  |  USP4  |  DISEASES
91179  |  SCARF2  |  DISEASES
1513  |  CTSK  |  DISEASES
5921  |  RASA1  |  DISEASES
8817  |  FGF18  |  DISEASES
222663  |  SCUBE3  |  DISEASES
170589  |  GPHA2  |  DISEASES
5741  |  PTH  |  DISEASES
83734  |  ATG10  |  DISEASES
654  |  BMP6  |  DISEASES
56172  |  ANKH  |  DISEASES
89780  |  WNT3A  |  DISEASES
340665  |  CYP26C1  |  DISEASES
23165  |  NUP205  |  DISEASES
342096  |  GOLGA6A  |  DISEASES
23474  |  ETHE1  |  DISEASES
7471  |  WNT1  |  DISEASES
4041  |  LRP5  |  DISEASES
3549  |  IHH  |  DISEASES
23001  |  WDFY3  |  DISEASES
5364  |  PLXNB1  |  DISEASES
84135  |  UTP15  |  DISEASES
1278  |  COL1A2  |  DISEASES
4982  |  TNFRSF11B  |  DISEASES
81501  |  DCSTAMP  |  DISEASES
5913  |  RAPSN  |  DISEASES
79158  |  GNPTAB  |  DISEASES
113201  |  CASC4  |  DISEASES
26585  |  GREM1  |  DISEASES
80700  |  UBXN6  |  DISEASES
50964  |  SOST  |  DISEASES
337876  |  CHSY3  |  DISEASES
3479  |  IGF1  |  DISEASES
121340  |  SP7  |  DISEASES
25928  |  SOSTDC1  |  DISEASES
6726  |  SRP9  |  DISEASES
1469  |  CST1  |  DISEASES
56246  |  MRAP  |  DISEASES
10238  |  DCAF7  |  DISEASES
23592  |  LEMD3  |  DISEASES
81029  |  WNT5B  |  DISEASES
3964  |  LGALS8  |  DISEASES
6578  |  SLCO2A1  |  DISEASES
118430  |  MUCL1  |  DISEASES
219855  |  SLC37A2  |  DISEASES
57592  |  ZNF687  |  DISEASES
4222  |  MEOX1  |  DISEASES
2253  |  FGF8  |  DISEASES
5745  |  PTH1R  |  DISEASES
56975  |  FAM20C  |  DISEASES
10491  |  CRTAP  |  DISEASES
1303  |  COL12A1  |  DISEASES
1435  |  CSF1  |  DISEASES
4772  |  NFATC1  |  DISEASES
9241  |  NOG  |  DISEASES
23046  |  KIF21B  |  DISEASES
9074  |  CLDN6  |  DISEASES
29110  |  TBK1  |  DISEASES
83999  |  KREMEN1  |  DISEASES
55666  |  NPLOC4  |  DISEASES
796  |  CALCA  |  DISEASES
60529  |  ALX4  |  DISEASES
2689  |  GH2  |  DISEASES
150372  |  NFAM1  |  DISEASES
3840  |  KPNA4  |  DISEASES
7189  |  TRAF6  |  DISEASES
2182  |  ACSL4  |  DISEASES
2261  |  FGFR3  |  DISEASES
4208  |  MEF2C  |  DISEASES
1758  |  DMP1  |  DISEASES
5781  |  PTPN11  |  DISEASES
7477  |  WNT7B  |  DISEASES
3178  |  HNRNPA1  |  DISEASES
4077  |  NBR1  |  DISEASES
6035  |  RNASE1  |  DISEASES
1499  |  CTNNB1  |  DISEASES
9672  |  SDC3  |  DISEASES
4205  |  MEF2A  |  DISEASES
3181  |  HNRNPA2B1  |  DISEASES
1785  |  DNM2  |  DISEASES
10656  |  KHDRBS3  |  DISEASES
2224  |  FDPS  |  DISEASES
55288  |  RHOT1  |  DISEASES
157680  |  VPS13B  |  DISEASES
9652  |  TTC37  |  DISEASES
7415  |  VCP  |  DISEASES
55102  |  ATG2B  |  DISEASES
80274  |  SCUBE1  |  DISEASES
5693  |  PSMB5  |  DISEASES
9859  |  CEP170  |  DISEASES
2590  |  GALNT2  |  DISEASES
632  |  BGLAP  |  DISEASES
2316  |  FLNA  |  DISEASES
10451  |  VAV3  |  DISEASES
2135  |  EXTL2  |  DISEASES
860  |  RUNX2  |  DISEASES
8471  |  IRS4  |  DISEASES
129685  |  TAF8  |  DISEASES
22943  |  DKK1  |  DISEASES
2134  |  EXTL1  |  DISEASES
3339  |  HSPG2  |  DISEASES
79695  |  GALNT12  |  DISEASES
81569  |  ACTL8  |  DISEASES
84701  |  COX4I2  |  DISEASES
7133  |  TNFRSF1B  |  DISEASES
4943  |  TBC1D25  |  DISEASES
26586  |  CKAP2  |  DISEASES
2131  |  EXT1  |  DISEASES
4038  |  LRP4  |  DISEASES
221044  |  UCMA  |  DISEASES
650  |  BMP2  |  DISEASES
5251  |  PHEX  |  DISEASES
4712  |  NDUFB6  |  DISEASES
203228  |  C9orf72  |  DISEASES
9365  |  KL  |  DISEASES
6902  |  TBCA  |  DISEASES
390874  |  ONECUT3  |  DISEASES
2254  |  FGF9  |  DISEASES
1186  |  CLCN7  |  DISEASES
8878  |  SQSTM1  |  DISEASES
11009  |  IL24  |  DISEASES
9208  |  LRRFIP1  |  DISEASES
220988  |  HNRNPA3  |  DISEASES
2591  |  GALNT3  |  DISEASES
114805  |  GALNT13  |  DISEASES
126549  |  ANKLE1  |  DISEASES
6164  |  RPL34  |  DISEASES
2132  |  EXT2  |  DISEASES
655  |  BMP7  |  DISEASES
5744  |  PTHLH  |  DISEASES
10020  |  GNE  |  DISEASES
55234  |  SMU1  |  DISEASES
9050  |  PSTPIP2  |  DISEASES
3267  |  AGFG1  |  DISEASES
6916  |  TBXAS1  |  DISEASES
3481  |  IGF2  |  DISEASES
197  |  AHSG  |  DISEASES
283463  |  MUC19  |  DISEASES
83876  |  MRO  |  DISEASES
7124  |  TNF  |  DISEASES
6424  |  SFRP4  |  DISEASES
10043  |  TOM1  |  DISEASES
151871  |  DPPA2  |  DISEASES
3712  |  IVD  |  DISEASES
6452  |  SH3BP2  |  DISEASES
9791  |  PTDSS1  |  DISEASES
7421  |  VDR  |  DISEASES
5053  |  PAH  |  DISEASES
3892  |  KRT86  |  DISEASES
9051  |  PSTPIP1  |  DISEASES
3949  |  LDLR  |  DISEASES
8792  |  TNFRSF11A  |  DISEASES
5886  |  RAD23A  |  DISEASES
Locus(Waiting for update.)
Disease ID 1791
Disease hyperostosis
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:20)
HP:0002015  |  Swallowing difficulty  |  3
HP:0002858  |  Mengiomia  |  3
HP:0002754  |  Bone infection  |  2
HP:0002664  |  Neoplasia  |  2
HP:0012189  |  Hodgkin disease  |  1
HP:0000365  |  Hearing impairment  |  1
HP:0001369  |  Arthritis  |  1
HP:0002797  |  Increased bone resorption  |  1
HP:0002176  |  Spinal cord compression  |  1
HP:0012740  |  Papilloma  |  1
HP:0100033  |  Tic disorder  |  1
HP:0002748  |  Rickets  |  1
HP:0000405  |  Conductive hearing loss  |  1
HP:0008513  |  Bilateral conductive hearing impairment  |  1
HP:0001138  |  Damaged optic nerve  |  1
HP:0002665  |  Lymphoma  |  1
HP:0012032  |  Lipoma  |  1
HP:0100009  |  Intracranial meningioma  |  1
HP:0002905  |  Hyperphosphatemia  |  1
HP:0011002  |  Osteopetrosis  |  1
Disease ID 1791
Disease hyperostosis
Manually Symptom(Waiting for update.)
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:0)
(Waiting for update.)
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)