PedAM

Pediatric Disease Annotations & Medicines


	growth failure

Disease ID	1823
Disease	growth failure
Definition	A condition of substandard growth or diminished capacity to maintain normal function.
Synonym	[d]failure to thrive [d]failure to thrive (context-dependent category) [d]failure to thrive (situation) failure to thrive failure to thrive (disorder) failure to thrive [disease/finding] failure to thrive syndrome failure to thrive-child failure-to-thrive ftt - failure to thrive thrive, failure to
UMLS	C0015544
MeSH	D005183
SNOMED-CT	SNOMEDCT_US_2016_09_01:54840006
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:38) C0013338 \| growth hormone deficiency \| 3 C0025958 \| microcephaly \| 2 C0038015 \| spondyloepiphyseal dysplasia \| 2 C0010674 \| cystic fibrosis \| 2 C0024523 \| malabsorption \| 2 C0023473 \| chronic myeloid leukemia \| 1 C0039730 \| thalassemia \| 1 C0221406 \| cushing disease \| 1 C0020676 \| hypothyroidism \| 1 C0751651 \| mitochondrial disease \| 1 C0001768 \| agammaglobulinemia \| 1 C0162429 \| nutritional deficiencies \| 1 C0162429 \| malnourished \| 1 C0002871 \| anemia \| 1 C0022658 \| renal disease \| 1 C0152021 \| congenital heart disease \| 1 C0162429 \| malnutrition \| 1 C0023470 \| myeloid leukemia \| 1 C0035078 \| renal failure \| 1 C0009319 \| colitis \| 1 C0006625 \| cachectic \| 1 C0035579 \| rickets \| 1 C0020676 \| hypothyroid \| 1 C0014130 \| endocrinopathy \| 1 C0002895 \| sickle-cell disease \| 1 C0022661 \| end-stage renal disease \| 1 C0026850 \| muscular dystrophy \| 1 C0018799 \| heart disease \| 1 C0041296 \| tuberculosis \| 1 C0011849 \| diabetes mellitus \| 1 C0004775 \| bartter syndrome \| 1 C0023418 \| leukemia \| 1 C0039730 \| thalassaemia \| 1 C0037315 \| sleep disordered breathing \| 1 C0022661 \| chronic renal failure \| 1 C0021831 \| enteropathy \| 1 C0028754 \| obesity \| 1 C0751651 \| mitochondrial diseases \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	(Waiting for update.)
Locus	(Waiting for update.)

Disease ID	1823
Disease	growth failure
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:37) HP:0000824 \| Growth hormone deficiency \| 3 HP:0000124 \| Renal tubular defect \| 3 HP:0001511 \| Prenatal onset growth retardation \| 2 HP:0000252 \| Small head circumference \| 2 HP:0002024 \| Intestinal malabsorption \| 2 HP:0002656 \| Epiphyseal dysplasia \| 2 HP:0003774 \| End-stage renal failure \| 2 HP:0002655 \| Spondyloepiphyseal dysplasia \| 2 HP:0001510 \| Growth deficiency \| 2 HP:0005506 \| Chronic myeloid leukemia \| 1 HP:0003560 \| Muscular dystrophy \| 1 HP:0010885 \| Aseptic necrosis \| 1 HP:0100033 \| Tic disorder \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0004432 \| Agammaglobulinaemia \| 1 HP:0001263 \| Developmental retardation \| 1 HP:0000832 \| Primary hypothyroidism \| 1 HP:0003510 \| Proportionate dwarfism \| 1 HP:0001513 \| Obesity \| 1 HP:0000819 \| Diabetes mellitus \| 1 HP:0002242 \| Enteropathy \| 1 HP:0000821 \| Underactive thyroid \| 1 HP:0001433 \| Enlarged liver and spleen \| 1 HP:0002748 \| Rickets \| 1 HP:0100543 \| Cognitive deficits \| 1 HP:0000992 \| Skin photosensitivity \| 1 HP:0004395 \| Malnutrition \| 1 HP:0001909 \| Leukemia \| 1 HP:0030759 \| Fat cell hypertrophy \| 1 HP:0002583 \| Colitis \| 1 HP:0001750 \| Single ventricle \| 1 HP:0001903 \| Anemia \| 1 HP:0001744 \| Splenomegaly \| 1 HP:0011968 \| Feeding difficulties \| 1 HP:0001249 \| Mental retardation \| 1 HP:0012324 \| Myeloid leukemia \| 1 HP:0010655 \| Stippled epiphyses \| 1

Disease ID	1823
Disease	growth failure
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:3) C0024523 \| malabsorption \| 2 C0009450 \| infection \| 2 C0028754 \| obesity \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:2)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs386601896	17848410	2908	NR3C1	umls:C0015544	BeFree	The 23K variant of the R23K polymorphism in the glucocorticoid receptor gene protects against postnatal growth failure and insulin resistance after preterm birth.	0.000271442	2007	NA	NA	NA	NA	NA
rs386601896	17848410	2908	NR3C1	umls:C0878787	BeFree	The 23K variant of the R23K polymorphism in the glucocorticoid receptor gene protects against postnatal growth failure and insulin resistance after preterm birth.	0.000271442	2007	NA	NA	NA	NA	NA

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:2)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0015544	reserpine	D012110	50-55-5	failure to thrive	MESH:D005183	marker/mechanism	6519379
C0015544	zidovudine	D015215	30516-87-1	failure to thrive	MESH:D005183	marker/mechanism	17304745

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

Web
Analytics