PedAM

Pediatric Disease Annotations & Medicines


	graves disease

Disease ID	507
Disease	graves disease
Definition	a condition usually caused by excessive production of thyroid hormone and characterized by an enlarged thyroid gland
Synonym	basedow dis basedow disease basedow's disease basedow's disease (disorder) basedows dis basedows disease disease graves disease graves' disease, basedow disease, basedow's disease, graves disease, graves' diseases graves exophthalmic goiter exophthalmic goiters exophthalmic goitre flajani disease goiter exophthalmic goiter, exophthalmic goiters, exophthalmic grave's disease graves dis graves disease [disease/finding] graves' disease graves' disease (disorder) graves' disease - hyperthyroidism graves' disease [ambiguous] graves' disease with exophthalmos hyperthyroidism hyperthyroidism graves disease hyperthyroidism, autoimmune morbus basedow toxic diffuse goiter with exophthalmos toxic diffuse goiter with exophthalmos (disorder) toxic diffuse goitre with exophthalmos
OMIM	OMIM:275000
DOID	DOID:12361
UMLS	C0018213
MeSH	D006111
SNOMED-CT	SNOMEDCT_US_2016_09_01:55807009;SNOMEDCT_US_2016_09_01:353295004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:113) C0020550 \| hyperthyroidism \| 61 C0040156 \| thyrotoxicosis \| 20 C0007115 \| thyroid ca \| 15 C0007115 \| thyroid cancer \| 11 C0026654 \| moyamoya \| 11 C0018021 \| goiter \| 9 C0026654 \| moyamoya disease \| 8 C0011847 \| diabetes \| 5 C0549473 \| thyroid carcinoma \| 5 C0745140 \| hyperthyroid \| 5 C0040137 \| thyroid nodule \| 5 C0019158 \| hepatitis \| 5 C0040137 \| thyroid nodules \| 5 C0026654 \| moyamoya syndrome \| 4 C0878544 \| cardiomyopathy \| 4 C0027145 \| myxedema \| 4 C0020538 \| hypertension \| 4 C0021053 \| immune disease \| 4 C0339143 \| graves' ophthalmopathy \| 4 C0030443 \| periodic paralysis \| 4 C0040127 \| thyroid storm \| 4 C0042870 \| vitamin d deficiency \| 3 C0030312 \| pancytopenia \| 3 C0019196 \| hepatitis c \| 3 C0024299 \| lymphoma \| 3 C0020676 \| hypothyroidism \| 3 C0020542 \| pulmonary hypertension \| 3 C0042870 \| vitamin d defic \| 3 C0040128 \| thyroid disease \| 3 C0011854 \| type 1 diabetes \| 3 C0002871 \| anemia \| 3 C0238463 \| papillary thyroid carcinoma \| 2 C0033975 \| psychosis \| 2 C0001824 \| agranulocytosis \| 2 C0007570 \| celiac disease \| 2 C0241910 \| autoimmune hepatitis \| 2 C0042900 \| vitiligo \| 2 C0020437 \| hypercalcemia \| 2 C0011849 \| diabetes mellitus \| 2 C0342122 \| diffuse toxic goiter \| 2 C0040127 \| thyrotoxic crisis \| 2 C0004134 \| ataxia \| 2 C0022658 \| nephropathy \| 2 C0040147 \| thyroiditis \| 2 C0015300 \| exophthalmos \| 2 C0001430 \| adenoma \| 2 C0238462 \| medullary thyroid cancer \| 1 C0221002 \| primary hyperparathyroidism \| 1 C0342127 \| toxic nodular goiter \| 1 C0042384 \| vasculitis \| 1 C0271333 \| orbital lymphoma \| 1 C0018021 \| struma \| 1 C0314719 \| dry eye \| 1 C0264832 \| peripartum cardiomyopathy \| 1 C0042109 \| hives \| 1 C0029132 \| optic neuropathy \| 1 C0022408 \| arthropathy \| 1 C0002170 \| alopecia \| 1 C0011570 \| depression \| 1 C0238358 \| hypokalemic periodic paralysis \| 1 C0027121 \| myositis \| 1 C0032460 \| polycystic ovary \| 1 C0238461 \| anaplastic thyroid carcinoma \| 1 C0042373 \| vascular disease \| 1 C0020255 \| hydrocephalus \| 1 C0001403 \| addison's disease \| 1 C0002171 \| alopecia areata \| 1 C0262587 \| parathyroid adenoma \| 1 C0743098 \| dermopathy \| 1 C0003467 \| anxiety \| 1 C0020502 \| hyperparathyroidism \| 1 C0553662 \| juvenile idiopathic arthritis \| 1 C0021359 \| infertility \| 1 C0001623 \| hypoadrenalism \| 1 C1509147 \| histiocytoma \| 1 C0242342 \| sheehan's syndrome \| 1 C0040053 \| thrombosis \| 1 C0677607 \| hashimoto's thyroiditis \| 1 C0162855 \| mucinosis \| 1 C0151468 \| thyroid adenoma \| 1 C0085278 \| antiphospholipid antibody syndrome \| 1 C0026848 \| myopathy \| 1 C0014130 \| endocrine disorders \| 1 C0085278 \| antiphospholipid syndrome \| 1 C0018021 \| goiters \| 1 C0272126 \| evans syndrome \| 1 C0339143 \| thyroid-associated ophthalmopathy \| 1 C0031046 \| pericarditis \| 1 C0020626 \| hypoparathyroidism \| 1 C0021345 \| infectious mononucleosis \| 1 C0334634 \| mantle cell lymphoma \| 1 C0016719 \| friedreich's ataxia \| 1 C0002453 \| amenorrhea \| 1 C0442874 \| neuropathy \| 1 C0346303 \| tshoma \| 1 C0026769 \| multiple sclerosis \| 1 C0014038 \| encephalitis \| 1 C0018801 \| cardiac failure \| 1 C0085655 \| polymyositis \| 1 C0015397 \| eye disease \| 1 C0022573 \| keratoconjunctivitis \| 1 C0015300 \| proptosis \| 1 C0038478 \| struma ovarii \| 1 C0011854 \| type 1 diabetes mellitus \| 1 C0039446 \| telangiectases \| 1 C1619734 \| pulmonary arterial hypertension \| 1 C0017661 \| iga nephropathy \| 1 C0032460 \| polycystic ovary syndrome \| 1 C0011880 \| diabetic ketoacidosis \| 1 C0031511 \| pheochromocytoma \| 1 C0021345 \| mononucleosis \| 1 C1261473 \| sarcoma \| 1 C0023895 \| liver disease \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:23) HLA-DRB1 \| 3123 \| GHR ITPR3 \| 3710 \| GWASCAT CTLA4 \| 1493 \| CTD_human;GHR CD40 \| 958 \| GHR GC \| 2638 \| CTD_human TSHR \| 7253 \| CTD_human;GWASCAT;GHR C6orf10 \| 10665 \| GWASCAT SCGB3A2 \| 117156 \| GHR TG \| 7038 \| GWASCAT;GHR PTPN22 \| 26191 \| CTD_human;GHR IL2RA \| 3559 \| GHR ARID5B \| 84159 \| CTD_human IFIH1 \| 64135 \| CTD_human C1QTNF6 \| 114904 \| GWASCAT ABO \| 28 \| GWASCAT B3GNT2 \| 10678 \| CTD_human MUC22 \| 100507679 \| GWASCAT SLAMF6 \| 114836 \| GWASCAT ABCF1 \| 23 \| GWASCAT HLA-J \| 3137 \| GWASCAT FCRL3 \| 115352 \| CTD_human;GWASCAT HLA-DPA2 \| 646702 \| GWASCAT RNASET2 \| 8635 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:86) 23 \| ABCF1 \| infer 28 \| ABO \| infer 328 \| APEX1 \| infer 60468 \| BACH2 \| infer 720 \| C4A \| infer 10665 \| C6orf10 \| infer 29126 \| CD274 \| infer 958 \| CD40 \| infer 1493 \| CTLA4 \| infer 1543 \| CYP1A1 \| infer 1565 \| CYP2D6 \| infer 2100 \| ESR2 \| infer 355 \| FAS \| infer 115352 \| FCRL3 \| infer 2638 \| GC \| infer 2944 \| GSTM1 \| infer 2950 \| GSTP1 \| infer 2952 \| GSTT1 \| infer 285834 \| HCG22 \| infer 3106 \| HLA-B \| infer 646702 \| HLA-DPA2 \| infer 3117 \| HLA-DQA1 \| infer 3119 \| HLA-DQB1 \| infer 3123 \| HLA-DRB1 \| infer 267015 \| HLA-S \| infer 3586 \| IL10 \| infer 3596 \| IL13 \| infer 3603 \| IL16 \| infer 3552 \| IL1A \| infer 3553 \| IL1B \| infer 3557 \| IL1RN \| infer 3562 \| IL3 \| infer 3565 \| IL4 \| infer 3630 \| INS \| infer 3710 \| ITPR3 \| infer 3802 \| KIR2DL1 \| infer 3803 \| KIR2DL2 \| infer 3804 \| KIR2DL3 \| infer 57292 \| KIR2DL5A \| infer 3806 \| KIR2DS1 \| infer 100132285 \| KIR2DS2 \| infer 3808 \| KIR2DS3 \| infer 3809 \| KIR2DS4 \| infer 3810 \| KIR2DS5 \| infer 3811 \| KIR3DL1 \| infer 3813 \| KIR3DS1 \| infer 344462 \| KRT18P39 \| infer 4295 \| MLN \| infer 394263 \| MUC21 \| infer 4792 \| NFKBIA \| infer 4795 \| NFKBIL1 \| infer 5133 \| PDCD1 \| infer 80380 \| PDCD1LG2 \| infer 5698 \| PSMB9 \| infer 5782 \| PTPN12 \| infer 26191 \| PTPN22 \| infer 399 \| RHOH \| infer 8635 \| RNASET2 \| infer 117156 \| SCGB3A2 \| infer 6401 \| SELE \| infer 7038 \| TG \| infer 7040 \| TGFB1 \| infer 7068 \| THRB \| infer 7124 \| TNF \| infer 7157 \| TP53 \| infer 7253 \| TSHR \| infer 7351 \| UCP2 \| infer 7421 \| VDR \| infer 7515 \| XRCC1 \| infer 56244 \| BTNL2 \| infer 868 \| CBLB \| infer 959 \| CD40LG \| infer 1628 \| DBP \| infer 2099 \| ESR1 \| infer 356 \| FASLG \| infer 3383 \| ICAM1 \| infer 3458 \| IFNG \| infer 3559 \| IL2RA \| infer 3569 \| IL6 \| infer 3659 \| IRF1 \| infer 4049 \| LTA \| infer 11099 \| PTPN21 \| infer 6402 \| SELL \| infer 387082 \| SUMO4 \| infer 6890 \| TAP1 \| infer 6891 \| TAP2 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:352) 50508 \| NOX3 \| DISEASES 3385 \| ICAM3 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 6480 \| ST6GAL1 \| DISEASES 27102 \| EIF2AK1 \| DISEASES 3956 \| LGALS1 \| DISEASES 140733 \| MACROD2 \| DISEASES 23439 \| ATP1B4 \| DISEASES 8237 \| USP11 \| DISEASES 7038 \| TG \| DISEASES 9694 \| EMC2 \| DISEASES 8797 \| TNFRSF10A \| DISEASES 973 \| CD79A \| DISEASES 9545 \| RAB3D \| DISEASES 6528 \| SLC5A5 \| DISEASES 10061 \| ABCF2 \| DISEASES 4353 \| MPO \| DISEASES 1440 \| CSF3 \| DISEASES 8688 \| KRT37 \| DISEASES 6198 \| RPS6KB1 \| DISEASES 8402 \| SLC25A11 \| DISEASES 4790 \| NFKB1 \| DISEASES 3558 \| IL2 \| DISEASES 969 \| CD69 \| DISEASES 1594 \| CYP27B1 \| DISEASES 3458 \| IFNG \| DISEASES 389434 \| IYD \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 7903 \| ST8SIA4 \| DISEASES 56920 \| SEMA3G \| DISEASES 5657 \| PRTN3 \| DISEASES 6402 \| SELL \| DISEASES 7276 \| TTR \| DISEASES 134637 \| ADAT2 \| DISEASES 1843 \| DUSP1 \| DISEASES 57616 \| TSHZ3 \| DISEASES 8997 \| KALRN \| DISEASES 1211 \| CLTA \| DISEASES 3759 \| KCNJ2 \| DISEASES 6431 \| SRSF6 \| DISEASES 8339 \| HIST1H2BG \| DISEASES 3306 \| HSPA2 \| DISEASES 4708 \| NDUFB2 \| DISEASES 5782 \| PTPN12 \| DISEASES 611 \| OPN1SW \| DISEASES 482 \| ATP1B2 \| DISEASES 3630 \| INS \| DISEASES 3958 \| LGALS3 \| DISEASES 759 \| CA1 \| DISEASES 7252 \| TSHB \| DISEASES 80263 \| TRIM45 \| DISEASES 2694 \| GIF \| DISEASES 60468 \| BACH2 \| DISEASES 90070 \| LACRT \| DISEASES 80896 \| NPL \| DISEASES 3569 \| IL6 \| DISEASES 2572 \| GAD2 \| DISEASES 27348 \| TOR1B \| DISEASES 7111 \| TMOD1 \| DISEASES 29953 \| TRHDE \| DISEASES 54665 \| RSBN1 \| DISEASES 845 \| CASQ2 \| DISEASES 51637 \| C14orf166 \| DISEASES 10681 \| GNB5 \| DISEASES 84888 \| SPPL2A \| DISEASES 23531 \| MMD \| DISEASES 6604 \| SMARCD3 \| DISEASES 671 \| BPI \| DISEASES 27178 \| IL37 \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 735 \| C9 \| DISEASES 55717 \| WDR11 \| DISEASES 64135 \| IFIH1 \| DISEASES 6403 \| SELP \| DISEASES 4036 \| LRP2 \| DISEASES 84273 \| NOA1 \| DISEASES 941 \| CD80 \| DISEASES 79031 \| PDCL3 \| DISEASES 56925 \| LXN \| DISEASES 59067 \| IL21 \| DISEASES 7067 \| THRA \| DISEASES 3818 \| KLKB1 \| DISEASES 5443 \| POMC \| DISEASES 2355 \| FOSL2 \| DISEASES 3383 \| ICAM1 \| DISEASES 1950 \| EGF \| DISEASES 10058 \| ABCB6 \| DISEASES 5172 \| SLC26A4 \| DISEASES 3480 \| IGF1R \| DISEASES 83417 \| FCRL4 \| DISEASES 3697 \| ITIH1 \| DISEASES 134864 \| TAAR1 \| DISEASES 5127 \| CDK16 \| DISEASES 56548 \| CHST7 \| DISEASES 84636 \| GPR174 \| DISEASES 8795 \| TNFRSF10B \| DISEASES 3439 \| IFNA1 \| DISEASES 84159 \| ARID5B \| DISEASES 10666 \| CD226 \| DISEASES 3606 \| IL18 \| DISEASES 283635 \| FAM177A1 \| DISEASES 7292 \| TNFSF4 \| DISEASES 5741 \| PTH \| DISEASES 1420 \| CRYGC \| DISEASES 7345 \| UCHL1 \| DISEASES 129831 \| RBM45 \| DISEASES 6750 \| SST \| DISEASES 5468 \| PPARG \| DISEASES 3017 \| HIST1H2BD \| DISEASES 539 \| ATP5O \| DISEASES 326 \| AIRE \| DISEASES 643 \| CXCR5 \| DISEASES 563 \| AZGP1 \| DISEASES 6352 \| CCL5 \| DISEASES 7412 \| VCAM1 \| DISEASES 2215 \| FCGR3B \| DISEASES 3973 \| LHCGR \| DISEASES 5798 \| PTPRN \| DISEASES 213 \| ALB \| DISEASES 132612 \| ADAD1 \| DISEASES 117156 \| SCGB3A2 \| DISEASES 7253 \| TSHR \| DISEASES 122769 \| LRR1 \| DISEASES 6778 \| STAT6 \| DISEASES 915 \| CD3D \| DISEASES 126306 \| JSRP1 \| DISEASES 3904 \| LAIR2 \| DISEASES 116285 \| ACSM1 \| DISEASES 5617 \| PRL \| DISEASES 129642 \| MBOAT2 \| DISEASES 3479 \| IGF1 \| DISEASES 10022 \| INSL5 \| DISEASES 3603 \| IL16 \| DISEASES 3308 \| HSPA4 \| DISEASES 3592 \| IL12A \| DISEASES 7200 \| TRH \| DISEASES 1493 \| CTLA4 \| DISEASES 260425 \| MAGI3 \| DISEASES 3596 \| IL13 \| DISEASES 154 \| ADRB2 \| DISEASES 10678 \| B3GNT2 \| DISEASES 3627 \| CXCL10 \| DISEASES 3575 \| IL7R \| DISEASES 2353 \| FOS \| DISEASES 6373 \| CXCL11 \| DISEASES 3037 \| HAS2 \| DISEASES 27087 \| B3GAT1 \| DISEASES 81793 \| TLR10 \| DISEASES 6169 \| RPL38 \| DISEASES 947 \| CD34 \| DISEASES 10008 \| KCNE3 \| DISEASES 57493 \| HEG1 \| DISEASES 84868 \| HAVCR2 \| DISEASES 3952 \| LEP \| DISEASES 55584 \| CHRNA9 \| DISEASES 23 \| ABCF1 \| DISEASES 55075 \| UACA \| DISEASES 57633 \| LRRN1 \| DISEASES 10859 \| LILRB1 \| DISEASES 79966 \| SCD5 \| DISEASES 4684 \| NCAM1 \| DISEASES 387082 \| SUMO4 \| DISEASES 7173 \| TPO \| DISEASES 29851 \| ICOS \| DISEASES 7358 \| UGDH \| DISEASES 80381 \| CD276 \| DISEASES 55024 \| BANK1 \| DISEASES 9370 \| ADIPOQ \| DISEASES 149233 \| IL23R \| DISEASES 8347 \| HIST1H2BC \| DISEASES 3039 \| HBA1 \| DISEASES 2027 \| ENO3 \| DISEASES 91012 \| CERS5 \| DISEASES 29122 \| PRSS50 \| DISEASES 353500 \| BMP8A \| DISEASES 284359 \| IZUMO1 \| DISEASES 6906 \| SERPINA7 \| DISEASES 11099 \| PTPN21 \| DISEASES 2520 \| GAST \| DISEASES 5136 \| PDE1A \| DISEASES 6401 \| SELE \| DISEASES 796 \| CALCA \| DISEASES 942 \| CD86 \| DISEASES 2152 \| F3 \| DISEASES 5138 \| PDE2A \| DISEASES 5133 \| PDCD1 \| DISEASES 6400 \| SEL1L \| DISEASES 8409 \| UXT \| DISEASES 84186 \| ZCCHC7 \| DISEASES 114904 \| C1QTNF6 \| DISEASES 1235 \| CCR6 \| DISEASES 3117 \| HLA-DQA1 \| DISEASES 966 \| CD59 \| DISEASES 117178 \| SSX2IP \| DISEASES 83659 \| TEKT1 \| DISEASES 79722 \| ANKRD55 \| DISEASES 921 \| CD5 \| DISEASES 23405 \| DICER1 \| DISEASES 3605 \| IL17A \| DISEASES 7332 \| UBE2L3 \| DISEASES 1861 \| TOR1A \| DISEASES 538 \| ATP7A \| DISEASES 64094 \| SMOC2 \| DISEASES 23111 \| SPG20 \| DISEASES 50488 \| MINK1 \| DISEASES 5979 \| RET \| DISEASES 355 \| FAS \| DISEASES 3841 \| KPNA5 \| DISEASES 8345 \| HIST1H2BH \| DISEASES 7068 \| THRB \| DISEASES 170685 \| NUDT10 \| DISEASES 8344 \| HIST1H2BE \| DISEASES 723961 \| INS-IGF2 \| DISEASES 3683 \| ITGAL \| DISEASES 987 \| LRBA \| DISEASES 60 \| ACTB \| DISEASES 6752 \| SSTR2 \| DISEASES 2764 \| GMFB \| DISEASES 3698 \| ITIH2 \| DISEASES 6775 \| STAT4 \| DISEASES 10004 \| NAALADL1 \| DISEASES 26191 \| PTPN22 \| DISEASES 8343 \| HIST1H2BF \| DISEASES 51150 \| SDF4 \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 7037 \| TFRC \| DISEASES 5646 \| PRSS3 \| DISEASES 83416 \| FCRL5 \| DISEASES 4283 \| CXCL9 \| DISEASES 10580 \| SORBS1 \| DISEASES 779 \| CACNA1S \| DISEASES 7052 \| TGM2 \| DISEASES 11116 \| FGFR1OP \| DISEASES 6993 \| DYNLT1 \| DISEASES 25802 \| LMOD1 \| DISEASES 5788 \| PTPRC \| DISEASES 51696 \| HECA \| DISEASES 356 \| FASLG \| DISEASES 84824 \| FCRLA \| DISEASES 2214 \| FCGR3A \| DISEASES 844 \| CASQ1 \| DISEASES 115350 \| FCRL1 \| DISEASES 115352 \| FCRL3 \| DISEASES 632 \| BGLAP \| DISEASES 3570 \| IL6R \| DISEASES 64077 \| LHPP \| DISEASES 4942 \| OAT \| DISEASES 153 \| ADRB1 \| DISEASES 965 \| CD58 \| DISEASES 10745 \| PHTF1 \| DISEASES 2773 \| GNAI3 \| DISEASES 2556 \| GABRA3 \| DISEASES 959 \| CD40LG \| DISEASES 292 \| SLC25A5 \| DISEASES 8022 \| LHX3 \| DISEASES 7422 \| VEGFA \| DISEASES 958 \| CD40 \| DISEASES 100 \| ADA \| DISEASES 9452 \| ITM2A \| DISEASES 2833 \| CXCR3 \| DISEASES 3710 \| ITPR3 \| DISEASES 3108 \| HLA-DMA \| DISEASES 5698 \| PSMB9 \| DISEASES 5696 \| PSMB8 \| DISEASES 3118 \| HLA-DQA2 \| DISEASES 2304 \| FOXE1 \| DISEASES 3303 \| HSPA1A \| DISEASES 3305 \| HSPA1L \| DISEASES 10673 \| TNFSF13B \| DISEASES 7918 \| GPANK1 \| DISEASES 50943 \| FOXP3 \| DISEASES 100507436 \| MICA \| DISEASES 3107 \| HLA-C \| DISEASES 2794 \| GNL1 \| DISEASES 3105 \| HLA-A \| DISEASES 7712 \| ZNF157 \| DISEASES 8346 \| HIST1H2BI \| DISEASES 8718 \| TNFRSF25 \| DISEASES 57623 \| ZFAT \| DISEASES 6520 \| SLC3A2 \| DISEASES 414062 \| CCL3L3 \| DISEASES 9308 \| CD83 \| DISEASES 7293 \| TNFRSF4 \| DISEASES 6643 \| SNX2 \| DISEASES 10186 \| LHFP \| DISEASES 3559 \| IL2RA \| DISEASES 3456 \| IFNB1 \| DISEASES 6462 \| SHBG \| DISEASES 3486 \| IGFBP3 \| DISEASES 3898 \| LAD1 \| DISEASES 122618 \| PLD4 \| DISEASES 3703 \| STT3A \| DISEASES 440603 \| BCL2L15 \| DISEASES 164 \| AP1G1 \| DISEASES 116985 \| ARAP1 \| DISEASES 84109 \| QRFPR \| DISEASES 79168 \| LILRA6 \| DISEASES 3382 \| ICA1 \| DISEASES 133690 \| CAPSL \| DISEASES 2687 \| GGT5 \| DISEASES 3119 \| HLA-DQB1 \| DISEASES 23308 \| ICOSLG \| DISEASES 2492 \| FSHR \| DISEASES 91319 \| DERL3 \| DISEASES 25983 \| NGDN \| DISEASES 7852 \| CXCR4 \| DISEASES 23274 \| CLEC16A \| DISEASES 3267 \| AGFG1 \| DISEASES 5073 \| PARN \| DISEASES 3384 \| ICAM2 \| DISEASES 3120 \| HLA-DQB2 \| DISEASES 7849 \| PAX8 \| DISEASES 6329 \| SCN4A \| DISEASES 720 \| C4A \| DISEASES 7124 \| TNF \| DISEASES 3106 \| HLA-B \| DISEASES 83463 \| MXD3 \| DISEASES 4049 \| LTA \| DISEASES 3115 \| HLA-DPB1 \| DISEASES 4050 \| LTB \| DISEASES 442721 \| LMOD2 \| DISEASES 3586 \| IL10 \| DISEASES 10665 \| C6orf10 \| DISEASES 3699 \| ITIH3 \| DISEASES 721 \| C4B \| DISEASES 8552 \| INE1 \| DISEASES 143662 \| MUC15 \| DISEASES 135656 \| DPCR1 \| DISEASES 56244 \| BTNL2 \| DISEASES 846 \| CASR \| DISEASES 2317 \| FLNB \| DISEASES 256987 \| SERINC5 \| DISEASES 2638 \| GC \| DISEASES 51428 \| DDX41 \| DISEASES 8635 \| RNASET2 \| DISEASES 930 \| CD19 \| DISEASES 55733 \| HHAT \| DISEASES 3684 \| ITGAM \| DISEASES 7421 \| VDR \| DISEASES 2972 \| BRF1 \| DISEASES 1734 \| DIO2 \| DISEASES 567 \| B2M \| DISEASES 9692 \| KIAA0391 \| DISEASES 10866 \| HCP5 \| DISEASES 102723508 \| KANTR \| DISEASES 348120 \| LINC01193 \| DISEASES 359809 \| PEG13 \| DISEASES 6023 \| RMRP \| DISEASES 677833 \| SNORA54 \| DISEASES 27004 \| TCL6 \| DISEASES
Locus	(Waiting for update.)

Disease ID	507
Disease	graves disease
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:92) HP:0000836 \| Overactive thyroid \| 61 HP:0000853 \| Goitre \| 9 HP:0030731 \| Carcinoma \| 7 HP:0002901 \| Hypocalcemia \| 6 HP:0002960 \| Autoimmune condition \| 6 HP:0012115 \| Liver inflammation \| 5 HP:0002890 \| Thyroid carcinoma \| 5 HP:0005110 \| Atrial fibrillation \| 4 HP:0000822 \| Hypertension \| 4 HP:0003470 \| Inability to move \| 4 HP:0001638 \| Cardiomyopathy \| 4 HP:0100512 \| Vitamin D deficiency \| 3 HP:0200028 \| Pretibial myxedema \| 3 HP:0000820 \| Thyroid abnormality \| 3 HP:0002665 \| Lymphoma \| 3 HP:0001903 \| Anemia \| 3 HP:0002930 \| Resistance to thyroid hormone \| 3 HP:0000821 \| Underactive thyroid \| 3 HP:0001876 \| Low blood cell count \| 3 HP:0000520 \| Anterior bulging of the globe of eye \| 3 HP:0003768 \| Periodic paralysis \| 3 HP:0002092 \| Pulmonary artery hypertension \| 3 HP:0001337 \| Tremor \| 2 HP:0010516 \| Enlarged thymus \| 2 HP:0100646 \| Thyroiditis \| 2 HP:0000112 \| Nephropathy \| 2 HP:0012234 \| Agranulocytosis \| 2 HP:0000855 \| Insulin resistance \| 2 HP:0002895 \| Papillary thyroid carcinoma \| 2 HP:0002608 \| Celiac disease \| 2 HP:0001045 \| Blotchy loss of skin color \| 2 HP:0003072 \| Hypercalcemia \| 2 HP:0001297 \| Cerebral vascular events \| 2 HP:0000709 \| Psychosis \| 2 HP:0001251 \| Ataxia \| 2 HP:0100028 \| Abnormal thryoid location \| 1 HP:0000789 \| Infertility \| 1 HP:0010871 \| Ataxia, sensory \| 1 HP:0011779 \| Anaplastic thyroid carcinoma \| 1 HP:0005681 \| Juvenile idiopathic arthritis \| 1 HP:0100614 \| Muscle inflammation \| 1 HP:0200123 \| Chronic liver inflammation \| 1 HP:0002716 \| Lymph node hyperplasia \| 1 HP:0100644 \| Melanonychia \| 1 HP:0001701 \| Pericarditis \| 1 HP:0012156 \| Hemophagocytosis \| 1 HP:0001663 \| Ventricular fibrillation \| 1 HP:0003198 \| Myopathic changes \| 1 HP:0001953 \| Diabetic ketosis \| 1 HP:0000819 \| Diabetes mellitus \| 1 HP:0100242 \| Sarcoma \| 1 HP:0012315 \| Histiocytoma \| 1 HP:0000739 \| Anxiety \| 1 HP:0008207 \| Addison's disease \| 1 HP:0001635 \| Congestive heart failure \| 1 HP:0000846 \| Hypoadrenalism \| 1 HP:0003613 \| Antiphospholipid antibodies \| 1 HP:0100013 \| Tumours of the breast \| 1 HP:0000854 \| Thyroid adenoma \| 1 HP:0002633 \| Vasculitis \| 1 HP:0000843 \| Hyperparathyroidism \| 1 HP:0000829 \| Hypoparathyroidism \| 1 HP:0008200 \| Primary hyperparathyroidism \| 1 HP:0001138 \| Damaged optic nerve \| 1 HP:0012579 \| Minimal change glomerulonephritis \| 1 HP:0001298 \| Encephalopathy \| 1 HP:0000147 \| Sclerocystic ovaries \| 1 HP:0000952 \| Yellow skin \| 1 HP:0002383 \| Encephalitis \| 1 HP:0100029 \| Lingual thyroid \| 1 HP:0003326 \| Muscle pain \| 1 HP:0001096 \| Keratoconjunctivitis \| 1 HP:0002666 \| Pheochromocytoma \| 1 HP:0011780 \| Thyroid hemiagenesis \| 1 HP:0011665 \| Takotsubo cardiomyopathy \| 1 HP:0002229 \| Alopecia areata \| 1 HP:0003040 \| Arthropathy \| 1 HP:0000572 \| Visual loss \| 1 HP:0001609 \| Hoarseness \| 1 HP:0000951 \| dermatopathy \| 1 HP:0000238 \| Nonsyndromal hydrocephalus \| 1 HP:0001009 \| Telangiectases \| 1 HP:0001399 \| Liver failure \| 1 HP:0002910 \| Elevated transaminases \| 1 HP:0002897 \| Parathyroid adenoma \| 1 HP:0001596 \| Hair loss \| 1 HP:0001266 \| Choreoathetosis \| 1 HP:0000141 \| Abnormal absence of menstruation \| 1 HP:0001025 \| Hives \| 1 HP:0000872 \| Hashimoto's thyroiditis \| 1 HP:0000708 \| Behavioral problems \| 1 HP:0000716 \| Depression \| 1

Disease ID	507
Disease	graves disease
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:51) C0020550 \| hyperthyroidism \| 61 C0040156 \| thyrotoxicosis \| 20 C0007115 \| thyroid cancer \| 10 C0026654 \| moyamoya disease \| 7 C0018021 \| goiter \| 7 C0549473 \| thyroid carcinoma \| 5 C0026654 \| moyamoya syndrome \| 4 C0339143 \| graves' ophthalmopathy \| 4 C0020598 \| hypocalcemia \| 3 C0020676 \| hypothyroidism \| 3 C0040137 \| thyroid nodules \| 3 C0745140 \| hyperthyroid \| 3 C0030443 \| periodic paralysis \| 3 C0878544 \| cardiomyopathy \| 2 C0001430 \| adenoma \| 2 C0042900 \| vitiligo \| 2 C0001824 \| agranulocytosis \| 2 C0241910 \| autoimmune hepatitis \| 2 C0040137 \| thyroid nodule \| 2 C0040127 \| thyrotoxic crisis \| 2 C0004364 \| autoimmune diseases \| 2 C0020542 \| pulmonary hypertension \| 2 C0020437 \| hypercalcemia \| 2 C0015300 \| exophthalmos \| 2 C0018213 \| autoimmune hyperthyroidism \| 1 C0232197 \| fibrillation \| 1 C0743098 \| dermopathy \| 1 C0854359 \| insulin autoimmune syndrome \| 1 C0021053 \| immune disease \| 1 C0085584 \| encephalopathy \| 1 C0029132 \| optic neuropathy \| 1 C0240318 \| mediastinal mass \| 1 C0869147 \| neonatal hyperthyroidism \| 1 C0234665 \| lid retraction \| 1 C0040127 \| thyroid storm \| 1 C0238461 \| anaplastic thyroid carcinoma \| 1 C0033103 \| pretibial myxedema \| 1 C0042384 \| vasculitis \| 1 C0011854 \| type 1 diabetes mellitus \| 1 C0268446 \| thyrotoxic periodic paralysis \| 1 C0234665 \| eyelid retraction \| 1 C0040115 \| thymus hyperplasia \| 1 C0238358 \| hypokalemic periodic paralysis \| 1 C1619734 \| pulmonary arterial hypertension \| 1 C0264832 \| peripartum cardiomyopathy \| 1 C0238463 \| papillary thyroid carcinoma \| 1 C0027145 \| myxedema \| 1 C0015300 \| proptosis \| 1 C0334634 \| mantle cell lymphoma \| 1 C0342122 \| diffuse toxic goiter \| 1 C1998045 \| subclinical hyperthyroidism \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:127)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1053005	24081513	6774	STAT3	umls:C0018213	BeFree	We genotyped six single-nucleotide polymorphisms (SNPs) rs1053005, rs2293152, rs744166, rs17593222, rs2291281, and rs2291282 of STAT3 gene in 667 patients with autoimmune thyroid disease (417 Graves' disease (GD) and 250 Hashimoto's thyroiditis (HT)) and 301 healthy controls.	0.000271442	2013	STAT3	17	42313892	T	C
rs11652878	20417566	3682	ITGAE	umls:C0018213	BeFree	These data suggest that patients with Graves' disease in the presence of the G allele of SNP rs11652878, especially Ht5-GCGCG, in CD103 are less susceptible toward the development of GO.	0.000271442	2010	ITGAE	17	3751686	A	G
rs12101255	25122677	7253	TSHR	umls:C0018213	BeFree	We mapped an open chromatin region overlapping two adjacent GD-associated SNPs (rs12101255 and rs12101261) in intron 1 of the thyroid stimulating hormone receptor (TSHR) gene.	0.297858183	2014	TSHR	14	80984708	C	T
rs12101261	21841780	7253	TSHR	umls:C0018213	GWASCAT	Moreover, we identified strong associations of TSHR and major histocompatibility complex class II variants with persistently TRAb-positive Graves' disease.	0.297858183	2011	TSHR	14	80984885	C	T
rs12101261	24144966	7253	TSHR	umls:C0018213	BeFree	These findings indicate that rs12101261 and rs179243 are the possible causal SNPs for GD susceptibility in the TSHR gene and could serve as genetic markers to predict the outcome of pTRAb+ in GD patients.	0.297858183	2014	TSHR	14	80984885	C	T
rs12101261	25122677	7253	TSHR	umls:C0018213	BeFree	We mapped an open chromatin region overlapping two adjacent GD-associated SNPs (rs12101255 and rs12101261) in intron 1 of the thyroid stimulating hormone receptor (TSHR) gene.	0.297858183	2014	TSHR	14	80984885	C	T
rs12101261	21841780	7253	TSHR	umls:C0018213	GAD	[Moreover, we identified strong associations of TSHR and major histocompatibility complex class II variants with persistently TRAb-positive Graves' disease.]	0.297858183	2011	TSHR	14	80984885	C	T
rs12136280	24780075	3491	CYR61	umls:C0018213	BeFree	SNPs rs12136280 (odds ratio [OR] 1.29, p=0.002), rs6663606 (OR 1.26, p=0.004), and rs17534202 (OR 1.21, p=0.02) in BTG2 and rs3753793 (OR 1.21, p=0.03) in CYR61 were associated with GD.	0.000271442	2015	LINC01136	1	203302802	G	T
rs12136280	24780075	7832	BTG2	umls:C0018213	BeFree	SNPs rs12136280 (odds ratio [OR] 1.29, p=0.002), rs6663606 (OR 1.26, p=0.004), and rs17534202 (OR 1.21, p=0.02) in BTG2 and rs3753793 (OR 1.21, p=0.03) in CYR61 were associated with GD.	0.000271442	2015	LINC01136	1	203302802	G	T
rs12147587	23118423	7253	TSHR	umls:C0018213	BeFree	Fine mapping of the GD locus, 14q, revealed replicated association of the GD phenotype with two markers, rs12147587 and rs2284720, located within the NRXN3 and TSHR genes, respectively.	0.297858183	2013	NRXN3	14	78599316	G	T
rs12147587	23118423	9369	NRXN3	umls:C0018213	BeFree	Fine mapping of the GD locus, 14q, revealed replicated association of the GD phenotype with two markers, rs12147587 and rs2284720, located within the NRXN3 and TSHR genes, respectively.	0.000271442	2013	NRXN3	14	78599316	G	T
rs1265883	23612905	114836	SLAMF6	umls:C0018213	GWASCAT	In this study, we carried out a three-stage study in 9529 patients with GD and 9984 controls to identify new risk loci for GD and found genome-wide significant associations in the overall populations for five novel susceptibility loci: the GPR174-ITM2A at Xq21.1, C1QTNF6-RAC2 at 22q12.3-13.1, SLAMF6 at 1q23.2, ABO at 9q34.2 and an intergenic region harboring two non-coding RNAs at 14q32.2 and one previous indefinite locus, TG at 8q24.22 (Pcombined < 5 × 10(-8)).	0.120271442	2014	SLAMF6	1	160495121	C	A
rs1269486	22014209	2625	GATA3	umls:C0018213	BeFree	We genotyped -1514T/C (rs17250932) and -1993T/C (rs4794067) polymorphisms of TBX21, - 742C/G polymorphism (rs2184658) of HLX and -1420G/A polymorphism (rs1269486) of GATA3 in genomic DNA samples from Japanese patients; 51 patients with severe Hashimoto's disease (HD), 39 with mild HD, 66 with intractable Graves' disease (GD), in whom remission was difficult to induce, 47 with GD in remission and 79 healthy volunteers.	0.000271442	2012	GATA3;GATA3-AS1	10	8054236	A	G
rs12760457	20615141	26191	PTPN22	umls:C0018213	BeFree	We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3789604) of the PTPN22 and the two SNPs (rs706778 and rs3118470 in the IL2RA gene) in 456 Japanese patients with AITD (286 with GD, 170 with Hashimoto's thyroiditis) and 221 matched Japanese control subjects.	0.144722412	2010	PTPN22;AP4B1-AS1	1	113847126	C	T
rs1310182	20615141	26191	PTPN22	umls:C0018213	BeFree	We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3789604) of the PTPN22 and the two SNPs (rs706778 and rs3118470 in the IL2RA gene) in 456 Japanese patients with AITD (286 with GD, 170 with Hashimoto's thyroiditis) and 221 matched Japanese control subjects.	0.144722412	2010	PTPN22;AP4B1-AS1	1	113830881	A	G
rs1368408	20210668	3562	IL3	umls:C0018213	BeFree	Recently, two studies have reported association of single-nucleotide polymorphism (SNP) rs31480 in interleukin 3 (IL-3) and the rs1368408 and SNP75 (-623 approximately -622 AG/-T) SNPs in secretoglobulin family 3a member 2 (SCGB3A2) with GD and suggested that this may account for linkage to the 5q31-33 region in Oriental GD datasets.	0.00554839	2010	SCGB3A2	5	147878599	G	A
rs1368408	20210668	117156	SCGB3A2	umls:C0018213	BeFree	Association between the SCGB3A2 rs1368408 SNP and GD was detected (p = 0.007, odds ratio = 1.18, 95% confidence intervals = 1.05-1.33).	0.008458305	2010	SCGB3A2	5	147878599	G	A
rs17250932	22014209	2625	GATA3	umls:C0018213	BeFree	We genotyped -1514T/C (rs17250932) and -1993T/C (rs4794067) polymorphisms of TBX21, - 742C/G polymorphism (rs2184658) of HLX and -1420G/A polymorphism (rs1269486) of GATA3 in genomic DNA samples from Japanese patients; 51 patients with severe Hashimoto's disease (HD), 39 with mild HD, 66 with intractable Graves' disease (GD), in whom remission was difficult to induce, 47 with GD in remission and 79 healthy volunteers.	0.000271442	2012	TBX21	17	47731941	T	C
rs17534202	24780075	3491	CYR61	umls:C0018213	BeFree	SNPs rs12136280 (odds ratio [OR] 1.29, p=0.002), rs6663606 (OR 1.26, p=0.004), and rs17534202 (OR 1.21, p=0.02) in BTG2 and rs3753793 (OR 1.21, p=0.03) in CYR61 were associated with GD.	0.000271442	2015	NA	1	203312047	G	C
rs17534202	24780075	7832	BTG2	umls:C0018213	BeFree	SNPs rs12136280 (odds ratio [OR] 1.29, p=0.002), rs6663606 (OR 1.26, p=0.004), and rs17534202 (OR 1.21, p=0.02) in BTG2 and rs3753793 (OR 1.21, p=0.03) in CYR61 were associated with GD.	0.000271442	2015	NA	1	203312047	G	C
rs17593222	24081513	6774	STAT3	umls:C0018213	BeFree	We genotyped six single-nucleotide polymorphisms (SNPs) rs1053005, rs2293152, rs744166, rs17593222, rs2291281, and rs2291282 of STAT3 gene in 667 patients with autoimmune thyroid disease (417 Graves' disease (GD) and 250 Hashimoto's thyroiditis (HT)) and 301 healthy controls.	0.000271442	2013	STAT3	17	42360972	C	G
rs179243	24144966	7253	TSHR	umls:C0018213	BeFree	These findings indicate that rs12101261 and rs179243 are the possible causal SNPs for GD susceptibility in the TSHR gene and could serve as genetic markers to predict the outcome of pTRAb+ in GD patients.	0.297858183	2014	TSHR	14	80962220	T	C
rs179247	25061884	7253	TSHR	umls:C0018213	BeFree	Allele A of the rs179247 polymorphism in the TSHR gene is associated with lower risk of GO in young GD patients.	0.297858183	2014	TSHR	14	80966202	A	G
rs1799969	23242661	7066	THPO	umls:C0018213	BeFree	Although there is not association between ICAM1 (G241R and K469E), VCAM1 (T-1591C and T-833C), and E-selectin (S128R) SNPs and susceptibility to GD, higher anti-TPO in E-selectin 128 SR + RR, and lower TSH in ICAM1 469 KE + EE subjects suspect that these genotypes are prone to increased antithyroid autoantibody production with more accentuated TSH suppression in GD.	0.000814326	2012	ICAM1;LOC105372272	19	10284116	G	A
rs1800471	24742542	7040	TGFB1	umls:C0018213	BeFree	Arg25Pro (c.915G>C) polymorphism of transforming growth factor β1 gene increases the risk of developing Graves' disease.	0.005276948	2014	TGFB1	19	41352971	C	G
rs1801282	18624999	5468	PPARG	umls:C0018213	BeFree	The distribution of the Pro(12)Ala PPAR gamma gene polymorphism is equally present in patients with GD with or without TAO.	0.003452799	2009	PPARG	3	12351626	C	G
rs1805192	18624999	5468	PPARG	umls:C0018213	BeFree	The distribution of the Pro(12)Ala PPAR gamma gene polymorphism is equally present in patients with GD with or without TAO.	0.003452799	2009	PPARG	3	12379739	C	G
rs1990760	23734776	64135	IFIH1	umls:C0018213	BeFree	This meta-analysis demonstrates that the IFIH1 rs1990760 T-allele confers susceptibility to T1D, SLE, MS and RA and suggests that the IFIH1 rs1990760 polymorphism might have no effect on GD and AAD.	0.123181358	2014	IFIH1	2	162267541	C	T
rs1990760	18026693	64135	IFIH1	umls:C0018213	BeFree	Therefore we were unable to find the association of A946T polymorphism of the IFIH1 gene with the development of GD in a Chinese population.	0.123181358	2007	IFIH1	2	162267541	C	T
rs1991517	11887032	7253	TSHR	umls:C0018213	BeFree	The D727E variant of the TSHR gene is associated with Graves' disease in a Russian population.	0.297858183	2002	TSHR;LOC101928462	14	81144239	G	C
rs201796235	23242661	7066	THPO	umls:C0018213	BeFree	Although there is not association between ICAM1 (G241R and K469E), VCAM1 (T-1591C and T-833C), and E-selectin (S128R) SNPs and susceptibility to GD, higher anti-TPO in E-selectin 128 SR + RR, and lower TSH in ICAM1 469 KE + EE subjects suspect that these genotypes are prone to increased antithyroid autoantibody production with more accentuated TSH suppression in GD.	0.000814326	2012	THPO	3	184373513	C	T
rs2069812	20332709	3567	IL5	umls:C0018213	BeFree	The results suggested that the polymorphism of IL-3 (rs40401) and IL-5 (rs2069812) were associated with GD and GO susceptibility in Chinese population.	0.000542884	2010	IL5	5	132544224	A	G
rs2069812	20332709	3562	IL3	umls:C0018213	BeFree	The results suggested that the polymorphism of IL-3 (rs40401) and IL-5 (rs2069812) were associated with GD and GO susceptibility in Chinese population.	0.00554839	2010	IL5	5	132544224	A	G
rs2076530	16984233	56244	BTNL2	umls:C0018213	BeFree	Association of the BTNL2 rs2076530 single nucleotide polymorphism with Graves' disease appears to be secondary to DRB1 exon 2 position beta74.	0.002638474	2006	BTNL2;LOC101929163	6	32396039	T	C
rs2076530	16984233	129831	RBM45	umls:C0018213	BeFree	Association of the BTNL2 rs2076530 single nucleotide polymorphism with Graves' disease appears to be secondary to DRB1 exon 2 position beta74.	0.008414698	2006	BTNL2;LOC101929163	6	32396039	T	C
rs2184658	22014209	2625	GATA3	umls:C0018213	BeFree	We genotyped -1514T/C (rs17250932) and -1993T/C (rs4794067) polymorphisms of TBX21, - 742C/G polymorphism (rs2184658) of HLX and -1420G/A polymorphism (rs1269486) of GATA3 in genomic DNA samples from Japanese patients; 51 patients with severe Hashimoto's disease (HD), 39 with mild HD, 66 with intractable Graves' disease (GD), in whom remission was difficult to induce, 47 with GD in remission and 79 healthy volunteers.	0.000271442	2012	HLX;HLX-AS1;LOC105373280	1	220879115	C	G
rs2234919	10651846	7253	TSHR	umls:C0018213	BeFree	We determined the genetic variability of the 1st (CCC/ACC, P52T polymorphic variant) and 10th exons (bp 1012-1704) of the TSH receptor (TSHR) gene in Graves' disease.	0.297858183	2000	TSHR;CEP128	14	80955834	C	A,G
rs2234919	10924276	3557	IL1RN	umls:C0018213	BeFree	We studied polymorphism of Ala17Thr CTLA4, H60R LMP2, Pro52Thr TSHR, and IL1RN-VNTR in healthy controls (n = 93) and patients with Graves disease (n = 78) using PCR.	0.009815515	2000	TSHR;CEP128	14	80955834	C	A,G
rs2234919	10924276	7253	TSHR	umls:C0018213	BeFree	We studied polymorphism of Ala17Thr CTLA4, H60R LMP2, Pro52Thr TSHR, and IL1RN-VNTR in healthy controls (n = 93) and patients with Graves disease (n = 78) using PCR.	0.297858183	2000	TSHR;CEP128	14	80955834	C	A,G
rs2239610	19438904	26191	PTPN22	umls:C0018213	BeFree	The AA genotype of PTPN22 rs3789604 and AA genotype of FCRL3 rs7528684 were correlated with a reduced risk of GD, while the CC genotype of TSHR rs2239610 was associated with higher serum concentrations of FT4 and TRAb.	0.144722412	2010	TSHR;CEP128	14	80955913	G	C
rs2239610	19438904	7253	TSHR	umls:C0018213	BeFree	In addition, the TSHR rs2239610 SNP is related to the severity of Graves' disease.	0.297858183	2010	TSHR;CEP128	14	80955913	G	C
rs2243250	17208210	3569	IL6	umls:C0018213	BeFree	This study aimed to examine the association between promoter polymorphisms of Th1 and Th2 cytokine genes [interleukin-4 (IL-4 T-34C, A-81G, C-285T and T-589C), IL-6 (G-174C), IL-10 (A-592C and T-819C) and tumour necrosis factor-alpha (TNF-alpha G-238A and G-308A)] and Graves' disease (GD) in Taiwanese population.	0.007177041	2007	IL4	5	132673462	C	T
rs2243250	17208210	3586	IL10	umls:C0018213	BeFree	This study aimed to examine the association between promoter polymorphisms of Th1 and Th2 cytokine genes [interleukin-4 (IL-4 T-34C, A-81G, C-285T and T-589C), IL-6 (G-174C), IL-10 (A-592C and T-819C) and tumour necrosis factor-alpha (TNF-alpha G-238A and G-308A)] and Graves' disease (GD) in Taiwanese population.	0.006634157	2007	IL4	5	132673462	C	T
rs2243250	17208210	3565	IL4	umls:C0018213	BeFree	This study aimed to examine the association between promoter polymorphisms of Th1 and Th2 cytokine genes [interleukin-4 (IL-4 T-34C, A-81G, C-285T and T-589C), IL-6 (G-174C), IL-10 (A-592C and T-819C) and tumour necrosis factor-alpha (TNF-alpha G-238A and G-308A)] and Graves' disease (GD) in Taiwanese population.	0.012453989	2007	IL4	5	132673462	C	T
rs2243250	17208210	7124	TNF	umls:C0018213	BeFree	This study aimed to examine the association between promoter polymorphisms of Th1 and Th2 cytokine genes [interleukin-4 (IL-4 T-34C, A-81G, C-285T and T-589C), IL-6 (G-174C), IL-10 (A-592C and T-819C) and tumour necrosis factor-alpha (TNF-alpha G-238A and G-308A)] and Graves' disease (GD) in Taiwanese population.	0.032009073	2007	IL4	5	132673462	C	T
rs2243250	24628947	3565	IL4	umls:C0018213	BeFree	However, we failed to reveal any association between IL-4 rs2243250 polymorphism and systemic lupus erythematosus (SLE), type 1 diabetes (T1D) or Graves' disease (GD).	0.012453989	2014	IL4	5	132673462	C	T
rs225014	15542398	1734	DIO2	umls:C0018213	BeFree	This suggests that the Thr92Ala variant of the DIO2 gene is associated or may be in linkage disequilibrium with a functional DIO2 polymorphism which involves in the development of GD in a Russian population.	0.003452799	2004	DIO2	14	80203237	T	C
rs2273017	21900946	10665	C6orf10	umls:C0018213	GWASCAT	Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.	0.122367032	2011	C6orf10;LOC101929163	6	32369853	G	A
rs2273017	21900946	10665	C6orf10	umls:C0018213	GAD	[Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.]	0.122367032	2011	C6orf10;LOC101929163	6	32369853	G	A
rs2281388	21841780	646702	HLA-DPA2	umls:C0018213	GWASCAT	A genome-wide association study identifies two new risk loci for Graves' disease.	0.12	2011	NA	6	33092341	G	A
rs2284720	23118423	9369	NRXN3	umls:C0018213	BeFree	Fine mapping of the GD locus, 14q, revealed replicated association of the GD phenotype with two markers, rs12147587 and rs2284720, located within the NRXN3 and TSHR genes, respectively.	0.000271442	2013	TSHR	14	80976823	A	G
rs2284720	23118423	7253	TSHR	umls:C0018213	BeFree	Fine mapping of the GD locus, 14q, revealed replicated association of the GD phenotype with two markers, rs12147587 and rs2284720, located within the NRXN3 and TSHR genes, respectively.	0.297858183	2013	TSHR	14	80976823	A	G
rs2291281	24081513	6774	STAT3	umls:C0018213	BeFree	We genotyped six single-nucleotide polymorphisms (SNPs) rs1053005, rs2293152, rs744166, rs17593222, rs2291281, and rs2291282 of STAT3 gene in 667 patients with autoimmune thyroid disease (417 Graves' disease (GD) and 250 Hashimoto's thyroiditis (HT)) and 301 healthy controls.	0.000271442	2013	STAT3	17	42346443	G	A
rs2291282	24081513	6774	STAT3	umls:C0018213	BeFree	We genotyped six single-nucleotide polymorphisms (SNPs) rs1053005, rs2293152, rs744166, rs17593222, rs2291281, and rs2291282 of STAT3 gene in 667 patients with autoimmune thyroid disease (417 Graves' disease (GD) and 250 Hashimoto's thyroiditis (HT)) and 301 healthy controls.	0.000271442	2013	STAT3	17	42346547	T	C
rs2293152	24081513	6774	STAT3	umls:C0018213	BeFree	We genotyped six single-nucleotide polymorphisms (SNPs) rs1053005, rs2293152, rs744166, rs17593222, rs2291281, and rs2291282 of STAT3 gene in 667 patients with autoimmune thyroid disease (417 Graves' disease (GD) and 250 Hashimoto's thyroiditis (HT)) and 301 healthy controls.	0.000271442	2013	STAT3	17	42329511	G	T,C,A
rs2294025	23612905	7038	TG	umls:C0018213	GWASCAT	Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.	0.155362183	2014	TG	8	133133268	G	A
rs229527	23612905	114904	C1QTNF6	umls:C0018213	GWASCAT	In this study, we carried out a three-stage study in 9529 patients with GD and 9984 controls to identify new risk loci for GD and found genome-wide significant associations in the overall populations for five novel susceptibility loci: the GPR174-ITM2A at Xq21.1, C1QTNF6-RAC2 at 22q12.3-13.1, SLAMF6 at 1q23.2, ABO at 9q34.2 and an intergenic region harboring two non-coding RNAs at 14q32.2 and one previous indefinite locus, TG at 8q24.22 (Pcombined < 5 × 10(-8)).	0.120271442	2014	C1QTNF6	22	37185445	C	A
rs231775	12610047	1493	CTLA4	umls:C0018213	BeFree	The CTLA-4 49 A/G polymorphism was detected by the PCR-restriction fragment-length polymorphism (RFLP) method in 97 type 1 diabetic subjects and 20 patients with Graves' disease, a cohort which included 4 patients who also had type 1 diabetes.	0.228259749	2003	CTLA4	2	203867991	A	G,T
rs231775	18752454	1493	CTLA4	umls:C0018213	BeFree	Particularly, association of three polymorphic markers of CTLA4 gene, namely, C(-318)T, A49G, and (AT)n dinucleotide repeat, with Graves' disease was demonstrated in most of the population-based investigations.	0.228259749	2008	CTLA4	2	203867991	A	G,T
rs237025	15730420	387082	SUMO4	umls:C0018213	BeFree	No association of the codon 55 methionine to valine polymorphism in the SUMO4 gene with Graves' disease.	0.000271442	2005	TAB2;SUMO4	6	149400554	G	A
rs2476599	20615141	26191	PTPN22	umls:C0018213	BeFree	We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3789604) of the PTPN22 and the two SNPs (rs706778 and rs3118470 in the IL2RA gene) in 456 Japanese patients with AITD (286 with GD, 170 with Hashimoto's thyroiditis) and 221 matched Japanese control subjects.	0.144722412	2010	PTPN22;AP4B1-AS1	1	113820837	G	A
rs2476601	15531553	26191	PTPN22	umls:C0018213	GAD	[The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease.]	0.144722412	2004	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	16893384	26191	PTPN22	umls:C0018213	BeFree	Recently, a gain of function variant C1858T of the lymphoid-specific protein tyrosine phosphatase non-receptor (LYP, PTPN22) gene has been reported to be associated with several autoimmune disorders including Graves' disease, type 1 diabetes, rheumatoid arthritis and vitiligo.	0.144722412	2006	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	18305142	52	ACP1	umls:C0018213	BeFree	The disease association of the common 1858C>T Arg620Trp (rs2476601) nonsynonymous single nucleotide polymorphism (SNP) of protein tyrosine phosphatase; nonreceptor type 22 (PTPN22) on chromosome 1p13 has been confirmed in type 1 diabetes and also in other autoimmune diseases, including rheumatoid arthritis and Graves' disease.	0.000814326	2008	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	20615141	52	ACP1	umls:C0018213	BeFree	A missence single-nucleotide polymorphism (SNP) in the protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene known as R620W (rs2476601) was recently reported to be associated with several autoimmune diseases including Graves' disease (GD).	0.000814326	2010	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	19343596	26191	PTPN22	umls:C0018213	BeFree	Stratifying patients affected with AITDs according to their phenotype (Graves' disease and Hashimoto's thyroiditis) and RA patients according to the presence of rheumatoid factor (RF) and antibodies against cyclic citrullinated peptides (ACPA) did not show any significant association with PTPN22 R620W allele (p>0.05).	0.144722412	2009	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	21467606	26191	PTPN22	umls:C0018213	BeFree	We found a significant association between PTPN22 1858 C/T SNP and T1D and GD.	0.144722412	2011	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	18305142	26191	PTPN22	umls:C0018213	BeFree	The disease association of the common 1858C>T Arg620Trp (rs2476601) nonsynonymous single nucleotide polymorphism (SNP) of protein tyrosine phosphatase; nonreceptor type 22 (PTPN22) on chromosome 1p13 has been confirmed in type 1 diabetes and also in other autoimmune diseases, including rheumatoid arthritis and Graves' disease.	0.144722412	2008	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2797415	20615141	26191	PTPN22	umls:C0018213	BeFree	We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3789604) of the PTPN22 and the two SNPs (rs706778 and rs3118470 in the IL2RA gene) in 456 Japanese patients with AITD (286 with GD, 170 with Hashimoto's thyroiditis) and 221 matched Japanese control subjects.	0.144722412	2010	NA	NA	NA	NA	NA
rs3087243	20300120	348120	LINC01193	umls:C0018213	BeFree	In this study, we investigated 329 (240 TBII-positive and 89 TBII-negative) GD patients and 378 controls for the polymorphisms in HLA-A, -DPB1 and CTLA4 (CT60, rs3087243, A/G) to investigate the contribution of these factors in the susceptibility to GD.	0.005157396	2010	CTLA4	2	203874196	G	A
rs3087243	24697361	1493	CTLA4	umls:C0018213	BeFree	Taken together, our study suggested that the CT60 polymorphism (rs3087243) in CTLA-4 gene might confer susceptibility to the AITDs (GD/HT).	0.228259749	2015	CTLA4	2	203874196	G	A
rs3087243	24697361	348120	LINC01193	umls:C0018213	BeFree	Taken together, our study suggested that the CT60 polymorphism (rs3087243) in CTLA-4 gene might confer susceptibility to the AITDs (GD/HT).	0.005157396	2015	CTLA4	2	203874196	G	A
rs3118470	20615141	3559	IL2RA	umls:C0018213	BeFree	The GG allele of rs3118470 in the IL2RA gene was significantly associated with GD (p = 0.03), although the association was weak.	0.004538567	2010	IL2RA	10	6059750	T	A,C
rs3118470	20615141	26191	PTPN22	umls:C0018213	BeFree	We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3789604) of the PTPN22 and the two SNPs (rs706778 and rs3118470 in the IL2RA gene) in 456 Japanese patients with AITD (286 with GD, 170 with Hashimoto's thyroiditis) and 221 matched Japanese control subjects.	0.144722412	2010	IL2RA	10	6059750	T	A,C
rs3132613	21900946	23	ABCF1	umls:C0018213	GAD	[Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.]	0.122638474	2011	ABCF1	6	30569829	C	G
rs3132613	21900946	23	ABCF1	umls:C0018213	GWASCAT	Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.	0.122638474	2011	ABCF1	6	30569829	C	G
rs31480	20210668	3562	IL3	umls:C0018213	BeFree	Recently, two studies have reported association of single-nucleotide polymorphism (SNP) rs31480 in interleukin 3 (IL-3) and the rs1368408 and SNP75 (-623 approximately -622 AG/-T) SNPs in secretoglobulin family 3a member 2 (SCGB3A2) with GD and suggested that this may account for linkage to the 5q31-33 region in Oriental GD datasets.	0.00554839	2010	IL3;LOC105379174	5	132060639	C	T
rs3170794	23242661	7066	THPO	umls:C0018213	BeFree	Although there is not association between ICAM1 (G241R and K469E), VCAM1 (T-1591C and T-833C), and E-selectin (S128R) SNPs and susceptibility to GD, higher anti-TPO in E-selectin 128 SR + RR, and lower TSH in ICAM1 469 KE + EE subjects suspect that these genotypes are prone to increased antithyroid autoantibody production with more accentuated TSH suppression in GD.	0.000814326	2012	VCAM1	1	100719028	T	C
rs370409	21841780	60468	BACH2	umls:C0018213	GAD	[A genome-wide association study identifies two new risk loci for Graves' disease.]	0.003181358	2011	BACH2	6	90212021	C	A
rs3753793	24780075	7832	BTG2	umls:C0018213	BeFree	SNPs rs12136280 (odds ratio [OR] 1.29, p=0.002), rs6663606 (OR 1.26, p=0.004), and rs17534202 (OR 1.21, p=0.02) in BTG2 and rs3753793 (OR 1.21, p=0.03) in CYR61 were associated with GD.	0.000271442	2015	CYR61;DDAH1	1	85580205	A	C
rs3753793	24780075	3491	CYR61	umls:C0018213	BeFree	SNPs rs12136280 (odds ratio [OR] 1.29, p=0.002), rs6663606 (OR 1.26, p=0.004), and rs17534202 (OR 1.21, p=0.02) in BTG2 and rs3753793 (OR 1.21, p=0.03) in CYR61 were associated with GD.	0.000271442	2015	CYR61;DDAH1	1	85580205	A	C
rs3761548	24035934	50943	FOXP3	umls:C0018213	BeFree	Because a single nucleotide polymorphism (SNP) within the FoxP3 gene (rs3761548 in the promoter region) is associated with susceptibility to Graves' disease, this study detected rs3761548 in a hospital-based case-control study.	0.006634157	2013	FOXP3	X	49261784	G	T
rs3761549	24784317	50943	FOXP3	umls:C0018213	BeFree	In conclusion, these results may suggest that rs3761549G/A polymorphism in Foxp3 gene could contribute to GD development in females.	0.006634157	2015	FOXP3	X	49260888	G	A
rs3761959	21841780	115352	FCRL3	umls:C0018213	GAD	[A genome-wide association study identifies two new risk loci for Graves' disease.]	0.248729747	2011	FCRL3	1	157699488	C	T
rs3761959	21841780	115352	FCRL3	umls:C0018213	GWASCAT	A genome-wide association study identifies two new risk loci for Graves' disease.	0.248729747	2011	FCRL3	1	157699488	C	T
rs3789604	19438904	26191	PTPN22	umls:C0018213	BeFree	The AA genotype of PTPN22 rs3789604 and AA genotype of FCRL3 rs7528684 were correlated with a reduced risk of GD, while the CC genotype of TSHR rs2239610 was associated with higher serum concentrations of FT4 and TRAb.	0.144722412	2010	RSBN1;AP4B1-AS1	1	113812320	T	C,G
rs3789604	19438904	1493	CTLA4	umls:C0018213	BeFree	These preliminary results demonstrate that the immune-regulatory gene CTLA-4 and the thyroid-specific gene Tg contribute to the risk of Graves' disease with additive effects, while PTPN22 rs3789604 and FCRL3 rs7528684 polymorphisms are protective against the disease.	0.228259749	2010	RSBN1;AP4B1-AS1	1	113812320	T	C,G
rs3789604	20615141	26191	PTPN22	umls:C0018213	BeFree	We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3789604) of the PTPN22 and the two SNPs (rs706778 and rs3118470 in the IL2RA gene) in 456 Japanese patients with AITD (286 with GD, 170 with Hashimoto's thyroiditis) and 221 matched Japanese control subjects.	0.144722412	2010	RSBN1;AP4B1-AS1	1	113812320	T	C,G
rs3792876	26329403	6583	SLC22A4	umls:C0018213	BeFree	These results suggest a lack of association between the SLC22A4 gene polymorphism rs3792876 and susceptibility to GD, HT and AITD in a Chinese Han population.	0.000271442	2015	SLC22A4	5	132301616	C	T
rs3819025	22816799	3605	IL17A	umls:C0018213	BeFree	In conclusion, the results indicate that IL-17F/rs763780 polymorphisms may affect the susceptibility to AITD, and IL-17A/rs3819025 SNP is likely a protective factor to GD in the Chinese population.	0.001628651	2012	IL17A	6	52186476	G	A
rs3819025	22816799	112744	IL17F	umls:C0018213	BeFree	In conclusion, the results indicate that IL-17F/rs763780 polymorphisms may affect the susceptibility to AITD, and IL-17A/rs3819025 SNP is likely a protective factor to GD in the Chinese population.	0.000542884	2012	IL17A	6	52186476	G	A
rs3827440	24289805	84636	GPR174	umls:C0018213	BeFree	rs3827440, a nonsynonymous single nucleotide polymorphism within GPR174 gene in X chromosome, is associated with Graves' disease in Polish Caucasian population.	0.000814326	2013	GPR174	X	79171491	T	C,A
rs40401	20332709	3562	IL3	umls:C0018213	BeFree	The results suggested that the polymorphism of IL-3 (rs40401) and IL-5 (rs2069812) were associated with GD and GO susceptibility in Chinese population.	0.00554839	2010	IL3;LOC105379174	5	132060785	C	T
rs40401	20332709	3567	IL5	umls:C0018213	BeFree	The results suggested that the polymorphism of IL-3 (rs40401) and IL-5 (rs2069812) were associated with GD and GO susceptibility in Chinese population.	0.000542884	2010	IL3;LOC105379174	5	132060785	C	T
rs4248154	21900946	100507679	MUC22	umls:C0018213	GWASCAT	Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.	0.12	2011	MUC22	6	31034839	C	T
rs4248154	21900946	394263	MUC21	umls:C0018213	GAD	[Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.]	0.002367032	2011	MUC22	6	31034839	C	T
rs4313034	21900946	3137	HLA-J	umls:C0018213	GWASCAT	Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.	0.12	2011	HLA-J;ZNRD1-AS1	6	30006148	C	T
rs4313034	21900946	80862	ZNRD1-AS1	umls:C0018213	GWASCAT	Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.	0.12	2011	HLA-J;ZNRD1-AS1	6	30006148	C	T
rs4553808	16893393	1493	CTLA4	umls:C0018213	BeFree	In this study, associations of five CTLA4 single nucleotide polymorphisms (-1722A/G, -1661A/G, -318C/T, +49G/A, CT60) with GD risk and GO susceptibility in GD patients were investigated in a Chinese population.	0.228259749	2006	CTLA4	2	203866282	A	G
rs4713693	21900946	4295	MLN	umls:C0018213	GAD	[Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.]	0.002367032	2011	NA	6	33850152	T	C
rs4794067	22014209	2625	GATA3	umls:C0018213	BeFree	We genotyped -1514T/C (rs17250932) and -1993T/C (rs4794067) polymorphisms of TBX21, - 742C/G polymorphism (rs2184658) of HLX and -1420G/A polymorphism (rs1269486) of GATA3 in genomic DNA samples from Japanese patients; 51 patients with severe Hashimoto's disease (HD), 39 with mild HD, 66 with intractable Graves' disease (GD), in whom remission was difficult to induce, 47 with GD in remission and 79 healthy volunteers.	0.000271442	2012	TBX21	17	47731462	T	C
rs4947296	21841780	285834	HCG22	umls:C0018213	GAD	[A genome-wide association study identifies two new risk loci for Graves' disease.]	0.002367032	2011	NA	6	31090401	T	C
rs4969170	25770161	9021	SOCS3	umls:C0018213	BeFree	Patients with GD who carry the AA genotype of the rs4969170 SNP in SOCS3 are more susceptible to the development of GO.	0.000271442	2015	LOC101928674	17	78364457	A	G
rs4986938	20961965	2100	ESR2	umls:C0018213	BeFree	The association between rs4986938 (ESR2) and aSLE is a novel finding, consistent with our recent report associating this variant with Graves' disease.	0.003181358	2011	ESR2	14	64233098	C	T
rs505922	23612905	28	ABO	umls:C0018213	GWASCAT	In this study, we carried out a three-stage study in 9529 patients with GD and 9984 controls to identify new risk loci for GD and found genome-wide significant associations in the overall populations for five novel susceptibility loci: the GPR174-ITM2A at Xq21.1, C1QTNF6-RAC2 at 22q12.3-13.1, SLAMF6 at 1q23.2, ABO at 9q34.2 and an intergenic region harboring two non-coding RNAs at 14q32.2 and one previous indefinite locus, TG at 8q24.22 (Pcombined < 5 × 10(-8)).	0.122638474	2014	NA	NA	NA	NA	NA
rs505922	21841780	28	ABO	umls:C0018213	GAD	[A genome-wide association study identifies two new risk loci for Graves' disease.]	0.122638474	2011	NA	NA	NA	NA	NA
rs5498	23242661	6401	SELE	umls:C0018213	BeFree	ICAM1 K469E and E-selectin S128R polymorphisms could predispose to increased autoantibody production and TSH suppression in Graves' disease.	0.002909916	2012	ICAM1;ICAM4;LOC105372272	19	10285007	A	G
rs5498	23242661	3383	ICAM1	umls:C0018213	BeFree	ICAM1 K469E and E-selectin S128R polymorphisms could predispose to increased autoantibody production and TSH suppression in Graves' disease.	0.006091273	2012	ICAM1;ICAM4;LOC105372272	19	10285007	A	G
rs5498	23242661	7066	THPO	umls:C0018213	BeFree	Although there is not association between ICAM1 (G241R and K469E), VCAM1 (T-1591C and T-833C), and E-selectin (S128R) SNPs and susceptibility to GD, higher anti-TPO in E-selectin 128 SR + RR, and lower TSH in ICAM1 469 KE + EE subjects suspect that these genotypes are prone to increased antithyroid autoantibody production with more accentuated TSH suppression in GD.	0.000814326	2012	ICAM1;ICAM4;LOC105372272	19	10285007	A	G
rs598493	24798189	472	ATM	umls:C0018213	BeFree	The ATC haplotype (rs598493, rs661561 and rs610604) was associated with a decreased risk of GD.	0.000271442	2015	TNFAIP3	6	137874265	T	C
rs610604	24798189	472	ATM	umls:C0018213	BeFree	The ATC haplotype (rs598493, rs661561 and rs610604) was associated with a decreased risk of GD.	0.000271442	2015	TNFAIP3	6	137878280	G	T
rs6457617	21841780	3119	HLA-DQB1	umls:C0018213	GAD	[A genome-wide association study identifies two new risk loci for Graves' disease.]	0.035753177	2011	NA	6	32696074	C	T
rs661561	24798189	472	ATM	umls:C0018213	BeFree	The ATC haplotype (rs598493, rs661561 and rs610604) was associated with a decreased risk of GD.	0.000271442	2015	TNFAIP3	6	137876194	A	C
rs6663606	24780075	3491	CYR61	umls:C0018213	BeFree	SNPs rs12136280 (odds ratio [OR] 1.29, p=0.002), rs6663606 (OR 1.26, p=0.004), and rs17534202 (OR 1.21, p=0.02) in BTG2 and rs3753793 (OR 1.21, p=0.03) in CYR61 were associated with GD.	0.000271442	2015	NA	1	203295900	T	A
rs6663606	24780075	7832	BTG2	umls:C0018213	BeFree	SNPs rs12136280 (odds ratio [OR] 1.29, p=0.002), rs6663606 (OR 1.26, p=0.004), and rs17534202 (OR 1.21, p=0.02) in BTG2 and rs3753793 (OR 1.21, p=0.03) in CYR61 were associated with GD.	0.000271442	2015	NA	1	203295900	T	A
rs6832151	21841780	399	RHOH	umls:C0018213	GAD	[A genome-wide association study identifies two new risk loci for Graves' disease.]	0.002367032	2011	NA	4	40301616	G	A,T
rs706778	20615141	26191	PTPN22	umls:C0018213	BeFree	We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3789604) of the PTPN22 and the two SNPs (rs706778 and rs3118470 in the IL2RA gene) in 456 Japanese patients with AITD (286 with GD, 170 with Hashimoto's thyroiditis) and 221 matched Japanese control subjects.	0.144722412	2010	IL2RA	10	6056986	C	T
rs744166	24081513	6774	STAT3	umls:C0018213	BeFree	We genotyped six single-nucleotide polymorphisms (SNPs) rs1053005, rs2293152, rs744166, rs17593222, rs2291281, and rs2291282 of STAT3 gene in 667 patients with autoimmune thyroid disease (417 Graves' disease (GD) and 250 Hashimoto's thyroiditis (HT)) and 301 healthy controls.	0.000271442	2013	STAT3	17	42362183	A	G
rs7528684	23505439	115352	FCRL3	umls:C0018213	BeFree	Above data indicated that FCRL3 gene and its proxy SNP rs7528684 may be involved in the pathogenesis of GD by excessive inhibiting B cell receptor signaling and the impairment of suppressing function of Tregs.	0.248729747	2013	FCRL3	1	157701026	A	G
rs7528684	19438904	26191	PTPN22	umls:C0018213	BeFree	The AA genotype of PTPN22 rs3789604 and AA genotype of FCRL3 rs7528684 were correlated with a reduced risk of GD, while the CC genotype of TSHR rs2239610 was associated with higher serum concentrations of FT4 and TRAb.	0.144722412	2010	FCRL3	1	157701026	A	G
rs7528684	19438904	1493	CTLA4	umls:C0018213	BeFree	These preliminary results demonstrate that the immune-regulatory gene CTLA-4 and the thyroid-specific gene Tg contribute to the risk of Graves' disease with additive effects, while PTPN22 rs3789604 and FCRL3 rs7528684 polymorphisms are protective against the disease.	0.228259749	2010	FCRL3	1	157701026	A	G
rs763780	22816799	3605	IL17A	umls:C0018213	BeFree	In conclusion, the results indicate that IL-17F/rs763780 polymorphisms may affect the susceptibility to AITD, and IL-17A/rs3819025 SNP is likely a protective factor to GD in the Chinese population.	0.001628651	2012	IL17F;LOC105375088	6	52236941	T	C
rs763780	22816799	112744	IL17F	umls:C0018213	BeFree	In conclusion, the results indicate that IL-17F/rs763780 polymorphisms may affect the susceptibility to AITD, and IL-17A/rs3819025 SNP is likely a protective factor to GD in the Chinese population.	0.000542884	2012	IL17F;LOC105375088	6	52236941	T	C
rs9355610	25928629	8635	RNASET2	umls:C0018213	BeFree	Our results suggest that the rs9355610 tag SNP of RNASET2 gene is positively associated with susceptibility to GD in the Chinese Han population.	0.122638474	2015	LOC105378120	6	166969587	G	A
rs9355610	21841780	8635	RNASET2	umls:C0018213	GAD	[A genome-wide association study identifies two new risk loci for Graves' disease.]	0.122638474	2011	LOC105378120	6	166969587	G	A
rs9394159	21900946	3710	ITPR3	umls:C0018213	GWASCAT	Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.	0.125005506	2011	ITPR3	6	33650385	A	T
rs9394159	21900946	3710	ITPR3	umls:C0018213	GAD	[Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.]	0.125005506	2011	ITPR3	6	33650385	A	T

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:200)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	2529097	rs2843403	T	C	rs2843403	22922229	0.000000794	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
1	114377568	rs2476601	A	G	rs2476601	22922229	4.03E-16	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G,C
1	157641683	rs10908583	C	T	rs10908583	21841780	1.02E-08	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
1	157643867	rs2210911	A	G	rs2210911	21841780	6.28E-08	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
1	157668390	rs7522061	T	C	rs7522061	21841780	1.65E-08	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	FCRL3
1	157668390	rs7522061	T	C	rs7522061	22922229	0.0000108	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	157669278	rs3761959	C	T	rs3761959	21841780	2.00E-13	NA	1.23	[1.17-1.30]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs3761959-A	Research Support, Non-U.S. Gov't	A	FCRL3
1	157717028	rs7517644	A	G	rs7517644	21841780	5.59E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	FCRL2
1	157754359	rs12743184	A	G	rs12743184	21841780	1.16E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
1	157770241	rs2050568	C	T	rs2050568	21841780	3.70E-08	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	FCRL1
1	157780892	rs6689427	A	G	rs6689427	21841780	1.13E-08	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	FCRL1
1	157798000	rs2765493	G	A	rs2765493	21841780	6.73E-08	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
1	157805107	rs2765502	G	A	rs2765502	21841780	1.66E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	CD5L
1	157811392	rs2260040	G	A	rs2260040	21841780	9.13E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	CD5L
1	160441241	rs1149386	G	C	rs1149386	21900946	1.50E-08	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
1	160464911	rs1265883	C	A	rs1265883	23612905	2.00E-18	NA	1.34	[1.25-1.43]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs1265883-C	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	7051171	rs1013864	G	A	rs1013864	21841780	1.21E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
2	7056183	rs3806609	T	C	rs3806609	21841780	2.00E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	LOC386597
2	7060629	rs771274	C	T	rs771274	21841780	2.22E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	RNF144A
2	12640741	rs1534422	G	A	rs1534422	22922229	0.00000469	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G,A
2	204708646	rs231804	C	T	rs231804	21841780	2.12E-11	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
2	204721752	rs1024161	T	C	rs1024161	21841780	2.00E-17	NA	1.3	[1.23-1.38]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs1024161-T	Research Support, Non-U.S. Gov't	T	NA
2	204722752	rs926169	G	T	rs926169	21841780	8.48E-08	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
2	204740866	rs231726	C	T	rs231726	21841780	1.16E-13	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
2	204745003	rs11571297	T	C	rs11571297	22922229	2.81E-23	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	204763044	rs10197319	G	A	rs10197319	21841780	2.87E-08	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
2	204763882	rs3096851	A	C	rs3096851	21841780	3.69E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
2	204769054	rs3116504	A	G	rs3116504	21841780	3.57E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
3	36517935	rs9881075	C	A	rs9881075	21841780	6.39E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	STAC
3	124412153	rs333284	T	C	rs333284	21841780	1.57E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	KALRN
3	188125120	rs13093110	C	T	rs13093110	22922229	0.000000817	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	40303633	rs6832151	G	T	rs6832151	21841780	1.00E-13	NA	1.24	[1.17-1.31]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs6832151-G	Research Support, Non-U.S. Gov't	T	NA
4	72425266	rs1377528	G	T	rs1377528	21841780	7.46E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	SLC4A4
4	72425863	rs1453458	C	T	rs1453458	21841780	4.18E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
4	72428081	rs1563091	T	C	rs1563091	21841780	3.66E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	SLC4A4
6	29488249	rs2745400	A	G	rs2745400	21900946	9.00E-09	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G,A	NA
6	29510325	rs362540	G	A	rs362540	21900946	8.20E-09	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	29520787	rs446145	G	C	rs446145	21900946	2.10E-06	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
6	29520787	rs562085911	G	GCCAC	rs446145	21900946	2.10E-06	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
6	29635317	rs2071652	C	T	rs2071652	21900946	1.80E-10	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	MOG
6	29677835	rs1610591	A	C,G,T	rs1610591	21900946	1.10E-08	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	NA	NA
6	29731687	rs7759482	A	G	rs7759482	21900946	4.90E-11	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
6	29801474	rs2517892	T	C	rs2517892	21900946	3.90E-13	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G,A	NA
6	29806062	rs2254071	T	C	rs2254071	21900946	3.90E-12	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
6	29935250	rs3893464	G	A	rs3893464	21900946	2.00E-20	NA	1.53	[1.39-1.67]	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs3893464-G	Research Support, Non-U.S. Gov't	C	NA
6	29973925	rs4313034	C	T	rs4313034	21900946	2.00E-15	NA	1.67	[1.47-1.90]	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs4313034-T	Research Support, Non-U.S. Gov't	T	HLA-J
6	30055643	rs6909253	G	T	rs6909253	21900946	4.10E-10	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	30537606	rs3132613	C	G	rs3132613	21900946	1.00E-13	NA	1.43	[1.30-1.57]	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs3132613-C	Research Support, Non-U.S. Gov't	C	ABCF1
6	31002616	rs4248154	C	T	rs4248154	21900946	1.00E-13	NA	1.38	[1.27-1.50]	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs4248154-C	Research Support, Non-U.S. Gov't	T	MUC22
6	31058178	rs4947296	T	C	rs4947296	21841780	4.00E-51	NA	1.77	[1.65-1.91]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs4947296-C	Research Support, Non-U.S. Gov't	T	NA
6	31085382	rs3094214	C	A	rs3094214	21900946	5.20E-08	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	CDSN
6	31085382	rs540385376	C	A	rs3094214	21900946	5.20E-08	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	CDSN
6	31091273	rs3131000	G	C	rs3131000	21900946	2.60E-09	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	PSORS1C1
6	31091273	rs534526282	G	C	rs3131000	21900946	2.60E-09	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	PSORS1C1
6	31114573	rs2240064	G	A	rs2240064	21900946	1.40E-05	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	CCHCR1
6	31118565	rs130078	C	G	rs130078	21900946	3.90E-14	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	CCHCR1
6	31126944	rs3094187	C	T	rs3094187	21900946	2.80E-09	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	TCF19
6	31130078	rs2073723	T	C	rs2073723	21900946	1.00E-14	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	TCF19
6	31203886	rs6457349	A	T	rs6457349	21900946	5.10E-08	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
6	31254664	rs9380236	A	G	rs9380236	21900946	1.50E-11	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
6	31350704	rs1521	C	T	rs1521	21841780	2.00E-65	NA	1.92	[1.78-2.08]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs1521-T	Research Support, Non-U.S. Gov't	T	NA
6	31448563	rs2516512	C	T	rs2516512	21900946	7.80E-09	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	NA	NA
6	31503975	rs2075580	G	C	rs2075580	21900946	1.00E-09	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	DDX39B
6	31506648	rs933208	G	T	rs933208	21900946	2.10E-08	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	DDX39B
6	31543827	rs1800610	G	A	rs1800610	21900946	8.00E-08	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	TNF
6	31919578	rs2072633	A	G	rs2072633	21900946	6.60E-06	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	CFB
6	31922254	rs630379	A	C	rs630379	21900946	2.40E-07	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	RDBP
6	32337630	rs2273017	G	A	rs2273017	21900946	2.00E-22	NA	1.53	[1.40-1.66]	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs2273017-A	Research Support, Non-U.S. Gov't	C	C6orf10
6	32428285	rs6903608	C	T	rs6903608	21841780	5.12E-24	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	32663851	rs6457617	C	T	rs6457617	21841780	7.00E-33	NA	1.4	[1.32-1.48]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs6457617-T	Research Support, Non-U.S. Gov't	T	NA
6	32793981	rs1044043	A	C	rs1044043	21900946	9.50E-07	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	TAP2
6	33060118	rs2281388	G	A	rs2281388	21841780	2.00E-65	NA	1.64	[1.55-1.74]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs2281388-T	Research Support, Non-U.S. Gov't	C	NA
6	33595399	rs4711332	A	G	rs4711332	21900946	8.60E-09	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	ITPR3
6	33618162	rs9394159	A	T	rs9394159	21900946	4.00E-12	NA	1.36	[1.24-1.48]	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs9394159-T	Research Support, Non-U.S. Gov't	A	ITPR3
6	33817929	rs4713693	T	C	rs4713693	21900946	7.00E-13	NA	1.4	[1.28-1.53]	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs4713693-T	Research Support, Non-U.S. Gov't	T	NA
6	90876844	rs2474618	T	C	rs2474618	21841780	1.26E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	BACH2
6	90880035	rs2474619	C	A	rs2474619	21841780	1.07E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	BACH2
6	90899561	rs2501720	G	A	rs2501720	21841780	4.49E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	BACH2
6	90912594	rs12209546	C	T	rs12209546	21841780	1.48E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	BACH2
6	90921740	rs370409	C	A	rs370409	21841780	2.00E-06	NA	1.15	[1.09-1.22]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs370409-T	Research Support, Non-U.S. Gov't	T	BACH2
6	90927728	rs206916	T	C	rs206916	21841780	3.60E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	BACH2
6	90929301	rs9344996	T	C	rs9344996	21841780	7.68E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	BACH2
6	90929301	rs9344996	T	C	rs9344996	23612905	1.90E-05	NA	1.1	[1.05-1.14]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs9344996-G	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	90936894	rs206913	C	A	rs206913	21841780	2.85E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	BACH2
6	90947998	rs2655387	T	C	rs2655387	21841780	2.54E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	BACH2
6	90957463	rs3757247	C	T	rs3757247	21841780	8.18E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	BACH2
6	90975999	rs661713	G	A	rs661713	21841780	1.26E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	BACH2
6	90976768	rs72928038	G	A	rs72928038	22922229	0.00000363	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	90995817	rs953233	C	T	rs953233	21841780	7.86E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	BACH2
6	90999602	rs10498965	A	G	rs10498965	21841780	1.03E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	BACH2
6	91002494	rs597325	A	G	rs597325	21841780	1.02E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	BACH2
6	167352104	rs3777722	C	A	rs3777722	21841780	1.02E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	RNASET2
6	167353701	rs3777723	G	A	rs3777723	21841780	7.00E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	RNASET2
6	167360104	rs2236312	G	A	rs2236312	21841780	2.36E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	RNASET2
6	167360389	rs2236313	T	C	rs2236313	21841780	3.02E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	RNASET2
6	167360724	rs1079145	G	A	rs1079145	21841780	2.60E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	RNASET2
6	167373708	rs9366076	C	T	rs9366076	21841780	3.99E-09	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
6	167383075	rs9355610	G	A	rs9355610	21841780	7.00E-10	NA	1.19	[1.13-1.26]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs9355610-G	Research Support, Non-U.S. Gov't	G	NA
6	167383972	rs429083	T	C	rs429083	21841780	3.64E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
6	167399512	rs9366078	A	G	rs9366078	21841780	1.31E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
6	167403873	rs933243	C	A	rs933243	21841780	1.50E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
6	167411008	rs400837	T	C	rs400837	21841780	2.26E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
6	167418111	rs368397331	A	C	rs56101842	22922229	0.00000033	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	NA
6	167431147	rs12526548	C	T	rs12526548	21841780	5.98E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	FGFR1OP
6	167437988	rs2301436	C	T	rs2301436	21841780	1.37E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	FGFR1OP
6	167454097	rs162295	A	C	rs162295	21841780	1.13E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	167455139	rs162297	A	G	rs162297	21841780	3.75E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	167461501	rs12529876	G	A	rs12529876	21841780	1.04E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
6	167461562	rs10484530	C	T	rs10484530	21841780	1.26E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
6	167494397	rs6921588	C	A	rs6921588	21841780	1.38E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
6	167500562	rs204295	C	T	rs204295	21841780	7.79E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
6	167502638	rs1331301	A	C	rs1331301	21841780	4.61E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	167505791	rs6902119	T	C	rs6902119	21841780	1.33E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	167511766	rs150110	G	A	rs150110	21841780	8.28E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
7	23355241	rs17740440	C	T	rs17740440	21841780	5.69E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T,C	IGF2BP3
7	34940039	rs10252228	A	G	rs10252228	21841780	8.13E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
7	79595829	rs981490	A	C	rs981490	21841780	2.49E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
7	134652029	rs17168135	G	A	rs17168135	21841780	1.65E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	CALD1
7	146701480	rs12669418	G	T	rs12669418	21841780	8.32E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	CNTNAP2
8	106903519	rs2088267	C	T	rs2088267	21841780	8.21E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
8	114440178	rs16884651	G	T	rs16884651	21841780	7.63E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	CSMD3
8	134087450	rs4301434	A	G	rs4301434	23612905	4.57E-07	NA	1.13	[1.08-1.18]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs4301434-G	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	134145512	rs2294025	G	A	rs2294025	23612905	8.00E-09	NA	1.16	[1.10-1.22]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs2294025-T	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	134185668	rs4736437	T	G	rs4736437	23612905	1.14E-08	NA	1.15	[1.10-1.21]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs4736437-C	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	134189138	rs10956695	T	C	rs10956695	23612905	2.19E-06	NA	1.13	[1.07-1.19]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs10956695-G	Meta-Analysis	Research Support, Non-U.S. Gov't	C
8	134214204	rs7005834	C	T	rs7005834	21841780	6.36E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	WISP1
8	143193540	rs728827	T	C	rs728827	21841780	5.61E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
9	136131188	rs8176749	C	T	rs8176749	21841780	2.59E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	ABO
9	136131322	rs8176746	G	T	rs8176746	21841780	4.56E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C,A	ABO
9	136131322	rs8176746	G	T	rs8176746	23612905	4.00E-06	NA	1.23	[1.06-1.18]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C,A
9	136139265	rs657152	C	A	rs657152	21841780	3.35E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	ABO
9	136149229	rs505922	T	C	rs505922	21841780	8.00E-06	NA	1.13	[1.07-1.20]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs505922-T	Research Support, Non-U.S. Gov't	T	ABO
9	136149229	rs505922	T	C	rs505922	23612905	2.00E-10	NA	1.14	[1.10-1.19]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
9	136149722	rs630014	A	G	rs630014	21841780	7.10E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	ABO
10	6098824	rs706779	T	C	rs706779	22922229	0.00000227	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
10	56742013	rs1219525	A	G	rs1219525	21841780	8.50E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
10	63982668	rs4147233	A	G	rs4147233	21841780	6.49E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	RTKN2
10	64067508	rs3910172	C	T	rs3910172	21841780	9.12E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
10	64069035	rs3864806	T	G	rs3864806	21841780	7.63E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
11	95311422	rs4409785	T	C	rs4409785	22922229	0.00000537	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	7600674	rs12368910	C	T	rs12368910	21841780	2.66E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
12	42869140	rs4768412	C	T	rs4768412	22922229	0.00000033	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	48434507	rs2240306	G	A	rs2240306	21900946	1.70E-08	NA	NA	NA	1,119 Japanese ancestry cases; 2,718 Japanese ancestry controls	Japanese(3837)	ALL(3837)	ASN(3837)	ALL(3837)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
12	104506318	rs10861159	G	A	rs10861159	21841780	4.49E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
12	126301003	rs6489020	C	T	rs6489020	21841780	4.30E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
12	126303338	rs10846982	G	A	rs10846982	21841780	4.75E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
12	126317824	rs2345779	G	T	rs2345779	21841780	8.64E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
12	126326568	rs1859943	A	G	rs1859943	21841780	8.73E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
12	126345752	rs733361	T	G	rs733361	21841780	6.96E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
12	126347014	rs929423	T	C	rs929423	21841780	5.42E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
14	77492891	rs879027	G	A	rs879027	21841780	9.51E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	IRF2BPL
14	77507205	rs10873301	G	T	rs10873301	21841780	5.43E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
14	77519693	rs4021419	T	C	rs4021419	21841780	2.04E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
14	77524587	rs8022640	G	A	rs8022640	21841780	5.36E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	NA
14	77532688	rs4903539	T	G	rs4903539	21841780	3.26E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
14	77581481	rs3813543	C	A	rs3813543	21841780	5.78E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	KIAA1737
14	81260377	rs162171	A	C	rs162171	21841780	4.55E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	CEP128
14	81271071	rs327434	G	A	rs327434	21841780	2.70E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	CEP128
14	81294256	rs162174	C	T	rs162174	21841780	5.08E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	CEP128
14	81315792	rs7158936	A	G	rs7158936	21841780	2.65E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A,G	CEP128
14	81346166	rs2556611	G	A	rs2556611	21841780	9.81E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	CEP128
14	81368817	rs12050151	T	C	rs12050151	21841780	3.88E-10	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	CEP128
14	81415154	rs2217177	T	C	rs2217177	21841780	8.43E-09	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
14	81420774	rs2371462	T	C	rs2371462	21841780	7.70E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	TSHR
14	81421423	rs8022600	G	T	rs8022600	21841780	4.80E-09	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	TSHR
14	81432546	rs179247	A	G	rs179247	21841780	5.83E-22	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	TSHR
14	81435199	rs179249	C	T	rs179249	21841780	2.05E-10	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	TSHR
14	81443167	rs2284720	A	G	rs2284720	21841780	1.63E-10	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	TSHR
14	81444367	rs2284722	G	A	rs2284722	21841780	5.15E-15	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	TSHR
14	81448382	rs3783949	T	G	rs3783949	21841780	3.45E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	TSHR
14	81451229	rs12101261	C	T	rs12101261	21841780	7.00E-24	NA	1.35	[1.28-1.43]	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs12101261-T	Research Support, Non-U.S. Gov't	T	TSHR
14	81456694	rs10145099	C	T	rs10145099	21841780	6.49E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	TSHR
14	81457572	rs17545038	T	C	rs17545038	21841780	1.56E-10	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	TSHR
14	81458762	rs2300519	T	A	rs2300519	22922229	1.34E-38	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
14	81458762	rs56885347	T	TAAA	rs2300519	22922229	1.34E-38	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
14	81468954	rs4903964	G	A	rs4903964	21841780	1.28E-18	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	TSHR
14	81471446	rs3783943	A	G	rs3783943	21841780	6.96E-06	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	TSHR
14	81497393	rs2300525	T	C	rs2300525	21841780	6.66E-07	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	TSHR
14	81523128	rs17111394	T	C	rs17111394	21841780	1.64E-09	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	TSHR
14	81524407	rs2268474	T	C	rs2268474	21841780	2.04E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	TSHR
14	98488007	rs1456988	G	T	rs1456988	23612905	5.00E-09	NA	1.12	[1.09-1.18]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
15	31665443	rs4779520	C	T	rs4779520	23612905	3.55E-05	NA	1.09	[1.05-1.14]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	rs4779520-G	Meta-Analysis	Research Support, Non-U.S. Gov't	T
15	63423739	rs1472631	A	G	rs1472631	21841780	2.80E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	LACTB
15	63435196	rs12899931	T	C	rs12899931	21841780	6.79E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
15	63436628	rs2729812	A	C	rs2729812	21841780	6.72E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
15	63445144	rs953978	C	T	rs953978	21841780	9.22E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
15	66990232	rs2053424	T	G	rs2053424	21841780	1.50E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	A	NA
16	31185882	rs57348955	G	A	rs57348955	22922229	3.76E-08	NA	NA	NA	2285 Graves' disease cases; 462 Hashimoto's thyroiditis cases; and 9364 controls	NOPOP(12111)	ALL(12111)	NOPOP(12111)	ALL(12111)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
16	89170171	rs7184784	T	C	rs7184784	21841780	8.77E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	ACSF3
16	89201805	rs4530136	A	G	rs4530136	21841780	6.07E-04	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	ACSF3
18	66930261	rs605314	G	T	rs605314	21841780	2.16E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	NA
19	6808656	rs12610223	G	A	rs12610223	21841780	3.67E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	VAV1
19	54989236	rs10425613	T	C	rs10425613	21841780	5.12E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	NA
20	13607380	rs6033777	C	T	rs6033777	21841780	7.35E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	TASP1
20	13618382	rs2423729	A	G	rs2423729	21841780	5.31E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	G	TASP1
20	19915251	rs16981330	G	T	rs16981330	21841780	8.25E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	T	RIN2
20	19916144	rs16981333	T	C	rs16981333	21841780	9.31E-05	NA	NA	NA	1,468 Chinese ancestry cases; 1,490 Chinese ancestry controls	Chinese(2958)	ALL(2958)	ASN(2958)	ALL(2958)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Research Support, Non-U.S. Gov't	C	RIN2
22	37581485	rs229527	C	A	rs229527	23612905	5.00E-20	NA	1.23	[1.19-1.30]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
22	37635055	rs2284038	A	G	rs2284038	23612905	6.40E-08	NA	1.12	[1.07-1.18]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
X	78497118	rs5912838	A	C	rs5912838	23612905	2.00E-33	NA	1.32	[1.25-1.37]	1,442 Han Chinese ancestry cases; 1,468 Han Chinese ancestry controls	Han Chinese(2910)	ALL(2910)	ASN(2910)	ALL(2910)	Graves' disease	HPOID:0100647	Graves disease	DOID:12361	Graves' disease	D006111	Graves Disease	EFOID:0004237	graves disease	Graves' disease	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:3)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0018213	carbimazole	D002231	22232-54-8	graves disease	MESH:D006111	therapeutic	12201214
C0018213	propranolol	D011433	525-66-6	graves disease	MESH:D006111	therapeutic	17462097
C0018213	propylthiouracil	D011441	51-52-5	graves disease	MESH:D006111	therapeutic	11922496

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)