PedAM
Pediatric Disease Annotations & Medicines
| gliomatosis cerebri | ||||
| Disease ID | 1157 |
|---|---|
| Disease | gliomatosis cerebri |
| Definition | A diffuse glial tumor which infiltrates the brain extensively, involving more than two lobes. It is frequently bilateral and often extends to the infratentorial structures, even to the spinal cord. It is probably of astrocytic origin, although GFAP expression may be scant or absent. (Adapted from WHO.) |
| Synonym | astrocytosis cerebri gliomatosis gliomatosis cerebri (morphologic abnormality) |
| Orphanet | |
| DOID | |
| UMLS | C0334576 |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:3) C1855995 | l-2-hydroxyglutaric aciduria | 1 C0014084 | ollier disease | 1 C0243010 | viral encephalitis | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:42) 123263 | MTFMT | DISEASES 4292 | MLH1 | DISEASES 4436 | MSH2 | DISEASES 2956 | MSH6 | DISEASES 968 | CD68 | DISEASES 2670 | GFAP | DISEASES 3021 | H3F3B | DISEASES 3417 | IDH1 | DISEASES 2581 | GALC | DISEASES 6855 | SYP | DISEASES 10000 | AKT3 | DISEASES 60482 | SLC5A7 | DISEASES 7297 | TYK2 | DISEASES 5395 | PMS2 | DISEASES 7157 | TP53 | DISEASES 1956 | EGFR | DISEASES 2264 | FGFR4 | DISEASES 84315 | MON1A | DISEASES 4255 | MGMT | DISEASES 23209 | MLC1 | DISEASES 10215 | OLIG2 | DISEASES 3418 | IDH2 | DISEASES 1641 | DCX | DISEASES 57142 | RTN4 | DISEASES 23583 | SMUG1 | DISEASES 5910 | RAP1GDS1 | DISEASES 4763 | NF1 | DISEASES 1969 | EPHA2 | DISEASES 3020 | H3F3A | DISEASES 10763 | NES | DISEASES 6280 | S100A9 | DISEASES 9118 | INA | DISEASES 3897 | L1CAM | DISEASES 5728 | PTEN | DISEASES 7422 | VEGFA | DISEASES 2170 | FABP3 | DISEASES 199 | AIF1 | DISEASES 974 | CD79B | DISEASES 1267 | CNP | DISEASES 57670 | KIAA1549 | DISEASES 4193 | MDM2 | DISEASES 79104 | MEG8 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1157 |
|---|---|
| Disease | gliomatosis cerebri |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:3) HP:0003150 | Glutaric aciduria | 1 HP:0002664 | Neoplasia | 1 HP:0040144 | L-2-hydroxyglutaric aciduria | 1 |
| Disease ID | 1157 |
|---|---|
| Disease | gliomatosis cerebri |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:3) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:2) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs121913500 | 21516462 | 9118 | INA | umls:C0334576 | BeFree | These data strongly suggest that INA and IDH1(R132H) mutant protein immunohistochemical analysis is of a great prognostic value in biopsied GC. | 0.000271442 | 2011 | IDH1 | 2 | 208248388 | C | T |
| rs121913500 | 21516462 | 3417 | IDH1 | umls:C0334576 | BeFree | These data strongly suggest that INA and IDH1(R132H) mutant protein immunohistochemical analysis is of a great prognostic value in biopsied GC. | 0.001085767 | 2011 | IDH1 | 2 | 208248388 | C | T |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |