PedAM

Pediatric Disease Annotations & Medicines


	gingivitis

Disease ID	1254
Disease	gingivitis
Definition	Inflammation of gum tissue (GINGIVA) without loss of connective tissue.
Synonym	gingival inflammation gingivitides gingivitis (disorder) gingivitis [disease/finding] gingivitis nos gingivitis, nos gum inflammation inflamed gums inflammation gum red and swollen gums
DOID	DOID:3087
UMLS	C0017574
MeSH	D005891
SNOMED-CT	SNOMEDCT_US_2016_09_01:66383009
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:16) C0031099 \| periodontitis \| 12 C0023646 \| lichen planus \| 3 C0011847 \| diabetes \| 2 C0011334 \| dental caries \| 2 C0011334 \| caries \| 2 C0028754 \| obesity \| 2 C0031090 \| periodontal disease \| 1 C0027726 \| nephrotic syndrome \| 1 C0037199 \| sinusitis \| 1 C0011854 \| type 1 diabetes \| 1 C0013298 \| duodenitis \| 1 C0030805 \| pemphigoid \| 1 C0030809 \| pemphigus vulgaris \| 1 C0022593 \| keratosis \| 1 C0022596 \| palmoplantar keratoderma \| 1 C0030807 \| pemphigus \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:6) 3586 \| IL10 \| infer 3606 \| IL18 \| infer 3552 \| IL1A \| infer 3553 \| IL1B \| infer 3557 \| IL1RN \| infer 4318 \| MMP9 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:189) 4710 \| NDUFB4 \| DISEASES 343641 \| TGM6 \| DISEASES 5008 \| OSM \| DISEASES 1511 \| CTSG \| DISEASES 3002 \| GZMB \| DISEASES 6655 \| SOS2 \| DISEASES 1472 \| CST4 \| DISEASES 7076 \| TIMP1 \| DISEASES 4313 \| MMP2 \| DISEASES 79650 \| USB1 \| DISEASES 10404 \| CPQ \| DISEASES 5327 \| PLAT \| DISEASES 973 \| CD79A \| DISEASES 10135 \| NAMPT \| DISEASES 5054 \| SERPINE1 \| DISEASES 5919 \| RARRES2 \| DISEASES 4353 \| MPO \| DISEASES 1440 \| CSF3 \| DISEASES 40 \| ASIC2 \| DISEASES 6347 \| CCL2 \| DISEASES 3558 \| IL2 \| DISEASES 1075 \| CTSC \| DISEASES 41 \| ASIC1 \| DISEASES 3458 \| IFNG \| DISEASES 3565 \| IL4 \| DISEASES 4057 \| LTF \| DISEASES 566 \| AZU1 \| DISEASES 9927 \| MFN2 \| DISEASES 6402 \| SELL \| DISEASES 1509 \| CTSD \| DISEASES 4317 \| MMP8 \| DISEASES 80306 \| MED28 \| DISEASES 8600 \| TNFSF11 \| DISEASES 3346 \| HTN1 \| DISEASES 22879 \| MON1B \| DISEASES 3976 \| LIF \| DISEASES 968 \| CD68 \| DISEASES 1215 \| CMA1 \| DISEASES 3630 \| INS \| DISEASES 55821 \| ALLC \| DISEASES 6382 \| SDC1 \| DISEASES 57050 \| UTP3 \| DISEASES 1401 \| CRP \| DISEASES 3569 \| IL6 \| DISEASES 4836 \| NMT1 \| DISEASES 3557 \| IL1RN \| DISEASES 7097 \| TLR2 \| DISEASES 4316 \| MMP7 \| DISEASES 4322 \| MMP13 \| DISEASES 4069 \| LYZ \| DISEASES 4025 \| LPO \| DISEASES 7077 \| TIMP2 \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 9424 \| KCNK6 \| DISEASES 1991 \| ELANE \| DISEASES 84680 \| ACCS \| DISEASES 10382 \| TUBB4A \| DISEASES 10190 \| TXNDC9 \| DISEASES 3589 \| IL11 \| DISEASES 3383 \| ICAM1 \| DISEASES 1161 \| ERCC8 \| DISEASES 9061 \| PAPSS1 \| DISEASES 6595 \| SMARCA2 \| DISEASES 55749 \| CCAR1 \| DISEASES 4060 \| LUM \| DISEASES 7112 \| TMPO \| DISEASES 5045 \| FURIN \| DISEASES 6455 \| SH3GL1 \| DISEASES 1513 \| CTSK \| DISEASES 133 \| ADM \| DISEASES 3606 \| IL18 \| DISEASES 163786 \| SASS6 \| DISEASES 146433 \| IL34 \| DISEASES 5739 \| PTGIR \| DISEASES 9442 \| MED27 \| DISEASES 6352 \| CCL5 \| DISEASES 213 \| ALB \| DISEASES 4982 \| TNFRSF11B \| DISEASES 1672 \| DEFB1 \| DISEASES 9311 \| ASIC3 \| DISEASES 84889 \| SLC7A3 \| DISEASES 5055 \| SERPINB2 \| DISEASES 4314 \| MMP3 \| DISEASES 56547 \| MMP26 \| DISEASES 116285 \| ACSM1 \| DISEASES 2990 \| GUSB \| DISEASES 140738 \| TMEM37 \| DISEASES 1673 \| DEFB4A \| DISEASES 4323 \| MMP14 \| DISEASES 5340 \| PLG \| DISEASES 92745 \| SLC38A5 \| DISEASES 258 \| AMBN \| DISEASES 931 \| MS4A1 \| DISEASES 414325 \| DEFB103A \| DISEASES 5345 \| SERPINF2 \| DISEASES 4312 \| MMP1 \| DISEASES 10615 \| SPAG5 \| DISEASES 284273 \| ZADH2 \| DISEASES 2 \| A2M \| DISEASES 2027 \| ENO3 \| DISEASES 55894 \| DEFB103B \| DISEASES 55258 \| THNSL2 \| DISEASES 633 \| BGN \| DISEASES 64806 \| IL25 \| DISEASES 1668 \| DEFA3 \| DISEASES 10456 \| HAX1 \| DISEASES 277 \| AMY1B \| DISEASES 6401 \| SELE \| DISEASES 682 \| BSG \| DISEASES 112744 \| IL17F \| DISEASES 64386 \| MMP25 \| DISEASES 391 \| RHOG \| DISEASES 3329 \| HSPD1 \| DISEASES 6575 \| SLC20A2 \| DISEASES 2804 \| GOLGB1 \| DISEASES 1508 \| CTSB \| DISEASES 6590 \| SLPI \| DISEASES 6633 \| SNRPD2 \| DISEASES 9536 \| PTGES \| DISEASES 3605 \| IL17A \| DISEASES 2879 \| GPX4 \| DISEASES 79661 \| NEIL1 \| DISEASES 5265 \| SERPINA1 \| DISEASES 3683 \| ITGAL \| DISEASES 6597 \| SMARCA4 \| DISEASES 6364 \| CCL20 \| DISEASES 5294 \| PIK3CG \| DISEASES 140803 \| TRPM6 \| DISEASES 10256 \| CNKSR1 \| DISEASES 9851 \| KIAA0753 \| DISEASES 54737 \| MPHOSPH8 \| DISEASES 5788 \| PTPRC \| DISEASES 5743 \| PTGS2 \| DISEASES 6675 \| UAP1 \| DISEASES 9191 \| DEDD \| DISEASES 632 \| BGLAP \| DISEASES 51175 \| TUBE1 \| DISEASES 6280 \| S100A9 \| DISEASES 4942 \| OAT \| DISEASES 1520 \| CTSS \| DISEASES 278 \| AMY1C \| DISEASES 276 \| AMY1A \| DISEASES 959 \| CD40LG \| DISEASES 7422 \| VEGFA \| DISEASES 4318 \| MMP9 \| DISEASES 1503 \| CTPS1 \| DISEASES 6406 \| SEMG1 \| DISEASES 57158 \| JPH2 \| DISEASES 50945 \| TBX22 \| DISEASES 7099 \| TLR4 \| DISEASES 23013 \| SPEN \| DISEASES 10673 \| TNFSF13B \| DISEASES 80324 \| PUS1 \| DISEASES 1471 \| CST3 \| DISEASES 7102 \| TSPAN7 \| DISEASES 9308 \| CD83 \| DISEASES 5272 \| SERPINB9 \| DISEASES 90865 \| IL33 \| DISEASES 2878 \| GPX3 \| DISEASES 3886 \| KRT35 \| DISEASES 9255 \| AIMP1 \| DISEASES 54826 \| GIN1 \| DISEASES 6654 \| SOS1 \| DISEASES 7009 \| TMBIM6 \| DISEASES 23210 \| JMJD6 \| DISEASES 7124 \| TNF \| DISEASES 7072 \| TIA1 \| DISEASES 8831 \| SYNGAP1 \| DISEASES 388372 \| CCL4L1 \| DISEASES 2821 \| GPI \| DISEASES 3612 \| IMPA1 \| DISEASES 55655 \| NLRP2 \| DISEASES 3586 \| IL10 \| DISEASES 629 \| CFB \| DISEASES 100289462 \| DEFB4B \| DISEASES 253970 \| SFTA3 \| DISEASES 930 \| CD19 \| DISEASES 441864 \| TARM1 \| DISEASES 3684 \| ITGAM \| DISEASES 8725 \| URI1 \| DISEASES 56342 \| PPAN \| DISEASES 820 \| CAMP \| DISEASES 1506 \| CTRL \| DISEASES 8792 \| TNFRSF11A \| DISEASES 5608 \| MAP2K6 \| DISEASES 246734 \| NPCDR1 \| DISEASES 6689 \| SPIB \| DISEASES 23642 \| SNHG1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1254
Disease	gingivitis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:21) HP:0000704 \| Pyorrhea \| 12 HP:0000670 \| Dental caries \| 3 HP:0006480 \| Premature loss of teeth \| 3 HP:0000230 \| Inflamed gums \| 3 HP:0002721 \| Immunodeficiency \| 2 HP:0001513 \| Obesity \| 2 HP:0010783 \| Erythema \| 1 HP:0000217 \| Dry mouth syndrome \| 1 HP:0000969 \| Dropsy \| 1 HP:0001065 \| Purplish striae \| 1 HP:0200034 \| Papule \| 1 HP:0000100 \| Nephrosis \| 1 HP:0030757 \| Dental abscess \| 1 HP:0000246 \| Sinus inflammation \| 1 HP:0000225 \| Gingival hemorrhage \| 1 HP:0000752 \| Hyperactive behavior \| 1 HP:0100825 \| Inflammation of the lips \| 1 HP:0012531 \| Pain \| 1 HP:0000982 \| Palmoplantar keratoderma \| 1 HP:0002653 \| Bone pain \| 1 HP:0012224 \| Circulating immune complexes \| 1

Disease ID	1254
Disease	gingivitis
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0031099 \| periodontitis \| 12 C0011389 \| dental plaque \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:2)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0017574	cyclosporine	D016572	59865-13-3	gingivitis	MESH:D005891	marker/mechanism	8176015
C0017574	lidocaine	D008012	137-58-6	gingivitis	MESH:D005891	marker/mechanism	11217590

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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