PedAM
Pediatric Disease Annotations & Medicines
| giant cell myocarditis | ||||
| Disease ID | 1143 |
|---|---|
| Disease | giant cell myocarditis |
| Definition | An often fatal inflammatory disorder that affects the myocardium. Morphologically, it is characterized by the presence of an inflammatory infiltrate in the myocardial tissue that includes multinucleated giant cells. It is often associated with the presence of an autoimmune disorder. Patients present with arrhythmias and/or heart failure. Heart transplantation is the only treatment option available. |
| Synonym | giant cell myocarditis (disorder) myocarditis, giant cell |
| UMLS | C0264856 |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:12) C0040100 | thymoma | 2 C0949691 | spondyloarthropathy | 1 C0032453 | relapsing polychondritis | 1 C0020437 | hypercalcemia | 1 C0021390 | inflammatory bowel disease | 1 C0205969 | malignant thymoma | 1 C0004245 | atrioventricular block | 1 C0021831 | bowel disease | 1 C0018801 | cardiac failure | 1 C0026896 | myasthenia gravis | 1 C0278846 | invasive thymoma | 1 C0042769 | virus infection | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1143 |
|---|---|
| Disease | giant cell myocarditis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:9) HP:0100522 | Thymoma | 2 HP:0001678 | Atrioventricular block | 1 HP:0001635 | Congestive heart failure | 1 HP:0003072 | Hypercalcemia | 1 HP:0003473 | Fatigable weakness | 1 HP:0004756 | Ventricular tachycardia | 1 HP:0004308 | Ventricular arrhythmia | 1 HP:0011675 | Arrhythmias | 1 HP:0001649 | Tachycardia | 1 |
| Disease ID | 1143 |
|---|---|
| Disease | giant cell myocarditis |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:6) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:2) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0001635 | Congestive heart failure | MP:0006113 | abnormal heart septum morphology; | |
Mapped by homologous gene(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0001649 | Tachycardia | MP:0005402 | abnormal action potential;HP:0001635 | Congestive heart failure |
Chemical(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |