PedAM
Pediatric Disease Annotations & Medicines
| gestational diabetes | ||||
| Disease ID | 665 |
|---|---|
| Disease | gestational diabetes |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:4) C0020538 | hypertension | 12 C0271650 | glucose intolerance | 5 C0032962 | pregnancy complications | 3 C0015938 | fetal macrosomia | 2 |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:240) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs10010131 | 18984664 | 7466 | WFS1 | umls:C0085207 | BeFree | All the risk alleles in the 11 examined type 2 diabetes risk variants showed an odds ratio (OR) greater than 1 for the GDM group compared with the control group ranging from 1.13 [95% confidence interval (CI) 0.88-1.46] to 1.44 (95% CI 1.19-1.74) except for the WFS1 rs10010131 variant with OR 0.87 (95% CI 0.73-1.05). | 0.000271442 | 2009 | WFS1 | 4 | 6291188 | A | G |
| rs1007888 | 25730019 | 4282 | MIF | umls:C0085207 | BeFree | Association between macrophage migration inhibitory factor rs1007888 and GDM. | 0.000542884 | 2016 | MIF-AS1 | 22 | 23898914 | C | T |
| rs10811661 | 19002430 | 3087 | HHEX | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 9 | 22134095 | T | C |
| rs10811661 | 19002430 | 1030 | CDKN2B | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 9 | 22134095 | T | C |
| rs10811661 | 19002430 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.123452799 | 2009 | NA | 9 | 22134095 | T | C |
| rs10811661 | 19002430 | 1029 | CDKN2A | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 9 | 22134095 | T | C |
| rs10811661 | 19002430 | 3630 | INS | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.023820871 | 2009 | NA | 9 | 22134095 | T | C |
| rs10811661 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | NA | 9 | 22134095 | T | C |
| rs10830963 | 24728128 | 3630 | INS | umls:C0085207 | BeFree | rs10830963 was associated cross-sectionally with fasting glucose (p = 0.0069), acute insulin response (AIR; p = 0.0013), disposition index (p = 0.00078), glucose effectiveness (p = 0.018) and gestational diabetes mellitus (OR 1.48; p = 0.012), but not with OGTT 30 min Δinsulin (the difference between the 30 min and fasting plasma insulin concentration) or 30 min insulin-based disposition index. | 0.023820871 | 2014 | MTNR1B | 11 | 92975544 | C | G |
| rs10830963 | 23690305 | 3667 | IRS1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.005352893 | 2013 | MTNR1B | 11 | 92975544 | C | G |
| rs10830963 | 22096510 | 3630 | INS | umls:C0085207 | BeFree | We also found that the risk alleles of rs2383208 (b = -0.085, p = 0.003), rs4402960 (b = -0.057, p = 0.046) and rs10830963 (b = -0.096, p = 0.001) were associated with HOMA-B, while rs7754840 was associated with decrease in insulin AUC during a 100 g OGTT given at the time of GDM diagnosis (b = -0.080, p = 0.007). | 0.023820871 | 2011 | MTNR1B | 11 | 92975544 | C | G |
| rs10830963 | 23690305 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.123452799 | 2013 | MTNR1B | 11 | 92975544 | C | G |
| rs10830963 | 22450346 | 4544 | MTNR1B | umls:C0085207 | BeFree | The rs10830963 variant of melatonin receptor MTNR1B is associated with increased risk for gestational diabetes mellitus in a Greek population. | 0.002171535 | 2012 | MTNR1B | 11 | 92975544 | C | G |
| rs10830963 | 23456907 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Among Caucasian women, GDM was associated with carriage of TCF7L2 rs7901695, MTNR1B rs10830963 and GCKR rs780094 alleles that are associated with T2DM and fasting glucose in nonpregnant populations. | 0.014254393 | 2014 | MTNR1B | 11 | 92975544 | C | G |
| rs10830963 | 23690305 | 4544 | MTNR1B | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.002171535 | 2013 | MTNR1B | 11 | 92975544 | C | G |
| rs10830963 | 23690305 | 3767 | KCNJ11 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.009172942 | 2013 | MTNR1B | 11 | 92975544 | C | G |
| rs10830963 | 23690305 | 10644 | IGF2BP2 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.12554839 | 2013 | MTNR1B | 11 | 92975544 | C | G |
| rs10830963 | 23690305 | 2645 | GCK | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.144808288 | 2013 | MTNR1B | 11 | 92975544 | C | G |
| rs1111875 | 19002430 | 1029 | CDKN2A | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 10 | 92703125 | C | T |
| rs1111875 | 19002430 | 3087 | HHEX | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 10 | 92703125 | C | T |
| rs1111875 | 19002430 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.123452799 | 2009 | NA | 10 | 92703125 | C | T |
| rs1111875 | 19002430 | 3630 | INS | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.023820871 | 2009 | NA | 10 | 92703125 | C | T |
| rs1111875 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | NA | 10 | 92703125 | C | T |
| rs1111875 | 19002430 | 1030 | CDKN2B | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 10 | 92703125 | C | T |
| rs1169288 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | HNF1A | 12 | 120978847 | A | C |
| rs1169288 | 16752173 | 6927 | HNF1A | umls:C0085207 | BeFree | The -30G-->A polymorphism of the beta-cell-specific promoter of GCK and the I27L polymorphism of HNF1A seem to increase the risk of GDM in Scandinavian women. | 0.010639772 | 2006 | HNF1A | 12 | 120978847 | A | C |
| rs1169288 | 16752173 | 2645 | GCK | umls:C0085207 | BeFree | The -30G-->A polymorphism of the beta-cell-specific promoter of GCK and the I27L polymorphism of HNF1A seem to increase the risk of GDM in Scandinavian women. | 0.144808288 | 2006 | HNF1A | 12 | 120978847 | A | C |
| rs1169288 | 16752173 | 5871 | MAP4K2 | umls:C0085207 | BeFree | The -30G-->A polymorphism of the beta-cell-specific promoter of GCK and the I27L polymorphism of HNF1A seem to increase the risk of GDM in Scandinavian women. | 0.000542884 | 2006 | HNF1A | 12 | 120978847 | A | C |
| rs11708067 | 23761423 | 7088 | TLE1 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | ADCY5 | 3 | 123346931 | A | G |
| rs11708067 | 23761423 | 111 | ADCY5 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | ADCY5 | 3 | 123346931 | A | G |
| rs11708067 | 23761423 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.014254393 | 2013 | ADCY5 | 3 | 123346931 | A | G |
| rs11708067 | 23761423 | 2646 | GCKR | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | ADCY5 | 3 | 123346931 | A | G |
| rs11708067 | 23761423 | 57818 | G6PC2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | ADCY5 | 3 | 123346931 | A | G |
| rs11708067 | 23761423 | 79068 | FTO | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000542884 | 2013 | ADCY5 | 3 | 123346931 | A | G |
| rs12243326 | 25973943 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Association with GDM was found for two of the most frequently replicated T2D loci: a TCF7L2 haplotype (CTTC: rs7901695, rs4506565, rs7903146, rs12243326; P=2.16 x 10(-06); OR=2.95) and a KCNQ1 haplotype (TTT: rs2237892, rs163184, rs2237897; P=1.98 x 10(-05); OR=0.55). | 0.014254393 | 2015 | TCF7L2 | 10 | 113029056 | T | C |
| rs12255372 | 23690305 | 2645 | GCK | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.144808288 | 2013 | TCF7L2 | 10 | 113049143 | G | T |
| rs12255372 | 23690305 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.123452799 | 2013 | TCF7L2 | 10 | 113049143 | G | T |
| rs12255372 | 23690305 | 3667 | IRS1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.005352893 | 2013 | TCF7L2 | 10 | 113049143 | G | T |
| rs12255372 | 23690305 | 10644 | IGF2BP2 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.12554839 | 2013 | TCF7L2 | 10 | 113049143 | G | T |
| rs12255372 | 23690305 | 3767 | KCNJ11 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.009172942 | 2013 | TCF7L2 | 10 | 113049143 | G | T |
| rs12255372 | 23690305 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Among them, genetic variants in TCF7L2 showed the strongest association with GDM risk, with ORs (95% CIs) of 1.44 (1.29-1.60, P < 0.001) per T allele of rs7903146 and 1.46 (1.15-1.84, P = 0.002) per T allele of rs12255372. | 0.014254393 | 2013 | TCF7L2 | 10 | 113049143 | G | T |
| rs12255372 | 23690305 | 4544 | MTNR1B | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.002171535 | 2013 | TCF7L2 | 10 | 113049143 | G | T |
| rs13266634 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | SLC30A8;LOC105375716 | 8 | 117172544 | C | T |
| rs137852671 | 20042013 | 6833 | ABCC8 | umls:C0085207 | BeFree | Hyperinsulinemic hypoglycemia evolving to gestational diabetes and diabetes mellitus in a family carrying the inactivating ABCC8 E1506K mutation. | 0.003181358 | 2010 | ABCC8 | 11 | 17394295 | C | T |
| rs1387153 | 23690305 | 3767 | KCNJ11 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.009172942 | 2013 | NA | 11 | 92940662 | C | T |
| rs1387153 | 23690305 | 3667 | IRS1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.005352893 | 2013 | NA | 11 | 92940662 | C | T |
| rs1387153 | 23690305 | 4544 | MTNR1B | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.002171535 | 2013 | NA | 11 | 92940662 | C | T |
| rs1387153 | 23690305 | 10644 | IGF2BP2 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.12554839 | 2013 | NA | 11 | 92940662 | C | T |
| rs1387153 | 23690305 | 2645 | GCK | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.144808288 | 2013 | NA | 11 | 92940662 | C | T |
| rs1387153 | 23690305 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.123452799 | 2013 | NA | 11 | 92940662 | C | T |
| rs1470579 | 22233651 | 10644 | IGF2BP2 | umls:C0085207 | GWASCAT | A genome-wide association study of gestational diabetes mellitus in Korean women. | 0.12554839 | 2012 | IGF2BP2 | 3 | 185811292 | A | C |
| rs1470579 | 22233651 | 10644 | IGF2BP2 | umls:C0085207 | GAD | [, we have confirmed that genetic variants in CDKAL1 and near MTNR1B are strongly associated with GDM in Korean women.] | 0.12554839 | 2012 | IGF2BP2 | 3 | 185811292 | A | C |
| rs1470579 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | IGF2BP2 | 3 | 185811292 | A | C |
| rs163184 | 25973943 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Association with GDM was found for two of the most frequently replicated T2D loci: a TCF7L2 haplotype (CTTC: rs7901695, rs4506565, rs7903146, rs12243326; P=2.16 x 10(-06); OR=2.95) and a KCNQ1 haplotype (TTT: rs2237892, rs163184, rs2237897; P=1.98 x 10(-05); OR=0.55). | 0.014254393 | 2015 | KCNQ1 | 11 | 2825839 | T | G |
| rs1799884 | 23690305 | 3767 | KCNJ11 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.009172942 | 2013 | GCK | 7 | 44189469 | C | T |
| rs1799884 | 23690305 | 4544 | MTNR1B | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.002171535 | 2013 | GCK | 7 | 44189469 | C | T |
| rs1799884 | 25633883 | 2645 | GCK | umls:C0085207 | BeFree | Association of the glucokinase gene promoter polymorphism -30G > A (rs1799884) with gestational diabetes mellitus susceptibility: a case-control study and meta-analysis. | 0.144808288 | 2015 | GCK | 7 | 44189469 | C | T |
| rs1799884 | 23690305 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.123452799 | 2013 | GCK | 7 | 44189469 | C | T |
| rs1799884 | 23690305 | 3667 | IRS1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.005352893 | 2013 | GCK | 7 | 44189469 | C | T |
| rs1799884 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | GCK | 7 | 44189469 | C | T |
| rs1799884 | 23690305 | 2645 | GCK | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.144808288 | 2013 | GCK | 7 | 44189469 | C | T |
| rs1799884 | 23690305 | 10644 | IGF2BP2 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.12554839 | 2013 | GCK | 7 | 44189469 | C | T |
| rs1799983 | 24403014 | 4846 | NOS3 | umls:C0085207 | BeFree | The association of endothelial nitric oxide synthase gene G894T polymorphism and serum nitric oxide concentration with microalbuminuria in patients with gestational diabetes. | 0.000542884 | 2014 | NOS3 | 7 | 150999023 | T | G |
| rs1799983 | 24403014 | 213 | ALB | umls:C0085207 | BeFree | The G894T polymorphism of eNOS gene and decreased NO concentration seem to be independent predictors of increased urinary excretion of albumin in patients with GDM. | 0.000542884 | 2014 | NOS3 | 7 | 150999023 | T | G |
| rs1800629 | 22070425 | 3586 | IL10 | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.002909916 | 2012 | TNF | 6 | 31575254 | G | A |
| rs1800629 | 22070425 | 7124 | TNF | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.026161616 | 2012 | TNF | 6 | 31575254 | G | A |
| rs1800629 | 22070425 | 3569 | IL6 | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.000814326 | 2012 | TNF | 6 | 31575254 | G | A |
| rs1800795 | 22070425 | 3586 | IL10 | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.002909916 | 2012 | IL6;LOC541472 | 7 | 22727026 | C | G |
| rs1800795 | 22070425 | 7124 | TNF | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.026161616 | 2012 | IL6;LOC541472 | 7 | 22727026 | C | G |
| rs1800795 | 22070425 | 3569 | IL6 | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.000814326 | 2012 | IL6;LOC541472 | 7 | 22727026 | C | G |
| rs1800896 | 22070425 | 7124 | TNF | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.026161616 | 2012 | IL10 | 1 | 206773552 | T | C |
| rs1800896 | 22070425 | 3586 | IL10 | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.002909916 | 2012 | IL10 | 1 | 206773552 | T | C |
| rs1800896 | 22070425 | 3569 | IL6 | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.000814326 | 2012 | IL10 | 1 | 206773552 | T | C |
| rs1801278 | 20540670 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Thus, our data suggest that the common T2D susceptibility polymorphism of TCF7L2 (rs7903146 C/T) gene, and the G972R polymorphism of the IRS1 gene, seem to predispose to GDM in Greek women. | 0.014254393 | 2011 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801278 | 16320083 | 3667 | IRS1 | umls:C0085207 | BeFree | Analysis of the IRS1 G972R polymorphism showed that RR homozygosity was found exclusively in women with GDM (91.0, 8.3 and 0.7% vs 90.7, 9.3 and 0.0% for GG, GR and RR genotypes, respectively; p=0.014). | 0.005352893 | 2005 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801278 | 23690305 | 3767 | KCNJ11 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.009172942 | 2013 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801278 | 17046546 | 155 | ADRB3 | umls:C0085207 | BeFree | We studied possible relations between GDM and both insulin receptor substrate 1 (IRS-1) (Gly972Arg) and beta3-adrenergic receptor (ADRB3 Trp64Arg, beta3-AR) gene mutations, considered potential modifying factors in the etiology of type 2 diabetes mellitus. | 0.003181358 | 2006 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801278 | 23690305 | 3667 | IRS1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.005352893 | 2013 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801278 | 23690305 | 10644 | IGF2BP2 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.12554839 | 2013 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801278 | 23690305 | 4544 | MTNR1B | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.002171535 | 2013 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801278 | 16522427 | 3667 | IRS1 | umls:C0085207 | BeFree | Association of insulin receptor substrate-1 G972R variant with baseline characteristics of the patients with gestational diabetes mellitus. | 0.005352893 | 2006 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801278 | 23690305 | 2645 | GCK | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.144808288 | 2013 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801278 | 20540670 | 3667 | IRS1 | umls:C0085207 | BeFree | Thus, our data suggest that the common T2D susceptibility polymorphism of TCF7L2 (rs7903146 C/T) gene, and the G972R polymorphism of the IRS1 gene, seem to predispose to GDM in Greek women. | 0.005352893 | 2011 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801278 | 23690305 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.123452799 | 2013 | IRS1 | 2 | 226795828 | C | T,G,A |
| rs1801282 | 17342473 | 155 | ADRB3 | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.003181358 | 2007 | PPARG | 3 | 12351626 | C | G |
| rs1801282 | 17342473 | 9370 | ADIPOQ | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.220427661 | 2007 | PPARG | 3 | 12351626 | C | G |
| rs1801282 | 17342473 | 2303 | FOXC2 | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.000271442 | 2007 | PPARG | 3 | 12351626 | C | G |
| rs1801282 | 18162503 | 5468 | PPARG | umls:C0085207 | BeFree | We hypothesized that interaction between PPARG2 Pro12Ala and variants in the promoter region of HNF4A are associated with type 2 diabetes-related quantitative traits in Mexican-American families of a proband with previous gestational diabetes. | 0.007177041 | 2008 | PPARG | 3 | 12351626 | C | G |
| rs1801282 | 17342473 | 5468 | PPARG | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.007177041 | 2007 | PPARG | 3 | 12351626 | C | G |
| rs1801282 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | PPARG | 3 | 12351626 | C | G |
| rs1801282 | 18162503 | 3172 | HNF4A | umls:C0085207 | BeFree | We hypothesized that interaction between PPARG2 Pro12Ala and variants in the promoter region of HNF4A are associated with type 2 diabetes-related quantitative traits in Mexican-American families of a proband with previous gestational diabetes. | 0.009544073 | 2008 | PPARG | 3 | 12351626 | C | G |
| rs1801282 | 23054024 | 5468 | PPARG | umls:C0085207 | BeFree | Quantitative assessment of the influence of PPARG P12A polymorphism on gestational diabetes mellitus risk. | 0.007177041 | 2013 | PPARG | 3 | 12351626 | C | G |
| rs1801282 | 21795447 | 5468 | PPARG | umls:C0085207 | BeFree | Association of the Pro12Ala and C1431T variants of PPARgamma and their haplotypes with susceptibility to gestational diabetes. | 0.007177041 | 2011 | PPARG | 3 | 12351626 | C | G |
| rs1801282 | 17342473 | 10891 | PPARGC1A | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.000542884 | 2007 | PPARG | 3 | 12351626 | C | G |
| rs1805097 | 24401133 | 8660 | IRS2 | umls:C0085207 | BeFree | The G1057D polymorphism of insulin receptor substrate-2 associated with gestational diabetes mellitus. | 0.000814326 | 2014 | IRS2 | 13 | 109782884 | C | T |
| rs1805192 | 18162503 | 5468 | PPARG | umls:C0085207 | BeFree | We hypothesized that interaction between PPARG2 Pro12Ala and variants in the promoter region of HNF4A are associated with type 2 diabetes-related quantitative traits in Mexican-American families of a proband with previous gestational diabetes. | 0.007177041 | 2008 | PPARG | 3 | 12379739 | C | G |
| rs1805192 | 23054024 | 5468 | PPARG | umls:C0085207 | BeFree | Quantitative assessment of the influence of PPARG P12A polymorphism on gestational diabetes mellitus risk. | 0.007177041 | 2013 | PPARG | 3 | 12379739 | C | G |
| rs1805192 | 17342473 | 5468 | PPARG | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.007177041 | 2007 | PPARG | 3 | 12379739 | C | G |
| rs1805192 | 21795447 | 5468 | PPARG | umls:C0085207 | BeFree | Association of the Pro12Ala and C1431T variants of PPARgamma and their haplotypes with susceptibility to gestational diabetes. | 0.007177041 | 2011 | PPARG | 3 | 12379739 | C | G |
| rs1805192 | 17342473 | 9370 | ADIPOQ | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.220427661 | 2007 | PPARG | 3 | 12379739 | C | G |
| rs1805192 | 17342473 | 2303 | FOXC2 | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.000271442 | 2007 | PPARG | 3 | 12379739 | C | G |
| rs1805192 | 17342473 | 10891 | PPARGC1A | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.000542884 | 2007 | PPARG | 3 | 12379739 | C | G |
| rs1805192 | 18162503 | 3172 | HNF4A | umls:C0085207 | BeFree | We hypothesized that interaction between PPARG2 Pro12Ala and variants in the promoter region of HNF4A are associated with type 2 diabetes-related quantitative traits in Mexican-American families of a proband with previous gestational diabetes. | 0.009544073 | 2008 | PPARG | 3 | 12379739 | C | G |
| rs1805192 | 17342473 | 155 | ADRB3 | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.003181358 | 2007 | PPARG | 3 | 12379739 | C | G |
| rs193922331 | NA | 2645 | GCK | umls:C0085207 | CLINVAR | NA | 0.144808288 | NA | GCK;LOC105375258 | 7 | 44147726 | A | G |
| rs2021966 | 25222839 | 5167 | ENPP1 | umls:C0085207 | BeFree | Body mass index associated to rs2021966 ENPP1 polymorphism increases the risk for gestational diabetes mellitus. | 0.000814326 | 2015 | ENPP1 | 6 | 131829299 | A | G |
| rs2237892 | 25973943 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Association with GDM was found for two of the most frequently replicated T2D loci: a TCF7L2 haplotype (CTTC: rs7901695, rs4506565, rs7903146, rs12243326; P=2.16 x 10(-06); OR=2.95) and a KCNQ1 haplotype (TTT: rs2237892, rs163184, rs2237897; P=1.98 x 10(-05); OR=0.55). | 0.014254393 | 2015 | KCNQ1 | 11 | 2818521 | C | T |
| rs2237895 | 19850681 | 3630 | INS | umls:C0085207 | BeFree | In the analyses of the GDM-related phenotype, only the risk allele of KCNQ1 rs2237895 was significantly associated with a high-level insulin sensitivity oral glucose tolerance test among patients with GDM (P = 0.0003, 0.004, and 0.05 for codominant, dominant, and recessive models, respectively). | 0.023820871 | 2010 | KCNQ1 | 11 | 2835964 | A | C |
| rs2237897 | 25973943 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Association with GDM was found for two of the most frequently replicated T2D loci: a TCF7L2 haplotype (CTTC: rs7901695, rs4506565, rs7903146, rs12243326; P=2.16 x 10(-06); OR=2.95) and a KCNQ1 haplotype (TTT: rs2237892, rs163184, rs2237897; P=1.98 x 10(-05); OR=0.55). | 0.014254393 | 2015 | KCNQ1 | 11 | 2837316 | C | T |
| rs2241766 | 22070425 | 3569 | IL6 | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.000814326 | 2012 | ADIPOQ;ADIPOQ-AS1 | 3 | 186853103 | T | G |
| rs2241766 | 22070425 | 3586 | IL10 | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.002909916 | 2012 | ADIPOQ;ADIPOQ-AS1 | 3 | 186853103 | T | G |
| rs2241766 | 22070425 | 7124 | TNF | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.026161616 | 2012 | ADIPOQ;ADIPOQ-AS1 | 3 | 186853103 | T | G |
| rs2383208 | 22096510 | 3630 | INS | umls:C0085207 | BeFree | We also found that the risk alleles of rs2383208 (b = -0.085, p = 0.003), rs4402960 (b = -0.057, p = 0.046) and rs10830963 (b = -0.096, p = 0.001) were associated with HOMA-B, while rs7754840 was associated with decrease in insulin AUC during a 100 g OGTT given at the time of GDM diagnosis (b = -0.080, p = 0.007). | 0.023820871 | 2011 | NA | 9 | 22132077 | A | G,T |
| rs266729 | 24068295 | 9370 | ADIPOQ | umls:C0085207 | BeFree | The rs266729 single-nucleotide polymorphism in the adiponectin gene shows association with gestational diabetes. | 0.220427661 | 2013 | ADIPOQ | 3 | 186841685 | C | G |
| rs266729 | 22070425 | 3569 | IL6 | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.000814326 | 2012 | ADIPOQ | 3 | 186841685 | C | G |
| rs266729 | 22070425 | 3586 | IL10 | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.002909916 | 2012 | ADIPOQ | 3 | 186841685 | C | G |
| rs266729 | 22070425 | 7124 | TNF | umls:C0085207 | BeFree | Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms. | 0.026161616 | 2012 | ADIPOQ | 3 | 186841685 | C | G |
| rs2796441 | 23761423 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.014254393 | 2013 | LOC101927502 | 9 | 81694033 | G | A |
| rs2796441 | 23761423 | 111 | ADCY5 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | LOC101927502 | 9 | 81694033 | G | A |
| rs2796441 | 23761423 | 2646 | GCKR | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | LOC101927502 | 9 | 81694033 | G | A |
| rs2796441 | 23761423 | 7088 | TLE1 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | LOC101927502 | 9 | 81694033 | G | A |
| rs2796441 | 23761423 | 57818 | G6PC2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | LOC101927502 | 9 | 81694033 | G | A |
| rs2796441 | 23761423 | 79068 | FTO | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000542884 | 2013 | LOC101927502 | 9 | 81694033 | G | A |
| rs3856806 | 21795447 | 5468 | PPARG | umls:C0085207 | BeFree | Association of the Pro12Ala and C1431T variants of PPARgamma and their haplotypes with susceptibility to gestational diabetes. | 0.007177041 | 2011 | PPARG | 3 | 12434058 | C | T |
| rs386597997 | 23690305 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.123452799 | 2013 | NA | NA | NA | NA | NA |
| rs386597997 | 23690305 | 10644 | IGF2BP2 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.12554839 | 2013 | NA | NA | NA | NA | NA |
| rs386597997 | 23690305 | 2645 | GCK | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.144808288 | 2013 | NA | NA | NA | NA | NA |
| rs386597997 | 23690305 | 3767 | KCNJ11 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.009172942 | 2013 | NA | NA | NA | NA | NA |
| rs386597997 | 16320083 | 3767 | KCNJ11 | umls:C0085207 | BeFree | Association of the E23K polymorphism in the KCNJ11 gene with gestational diabetes mellitus. | 0.009172942 | 2005 | NA | NA | NA | NA | NA |
| rs386597997 | 23690305 | 4544 | MTNR1B | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.002171535 | 2013 | NA | NA | NA | NA | NA |
| rs386597997 | 23690305 | 3667 | IRS1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.005352893 | 2013 | NA | NA | NA | NA | NA |
| rs4402960 | 22096510 | 3630 | INS | umls:C0085207 | BeFree | We also found that the risk alleles of rs2383208 (b = -0.085, p = 0.003), rs4402960 (b = -0.057, p = 0.046) and rs10830963 (b = -0.096, p = 0.001) were associated with HOMA-B, while rs7754840 was associated with decrease in insulin AUC during a 100 g OGTT given at the time of GDM diagnosis (b = -0.080, p = 0.007). | 0.023820871 | 2011 | IGF2BP2 | 3 | 185793899 | G | T |
| rs4402960 | 23690305 | 10644 | IGF2BP2 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.12554839 | 2013 | IGF2BP2 | 3 | 185793899 | G | T |
| rs4402960 | 23690305 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.123452799 | 2013 | IGF2BP2 | 3 | 185793899 | G | T |
| rs4402960 | 23690305 | 3767 | KCNJ11 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.009172942 | 2013 | IGF2BP2 | 3 | 185793899 | G | T |
| rs4402960 | 23690305 | 4544 | MTNR1B | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.002171535 | 2013 | IGF2BP2 | 3 | 185793899 | G | T |
| rs4402960 | 23690305 | 3667 | IRS1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.005352893 | 2013 | IGF2BP2 | 3 | 185793899 | G | T |
| rs4402960 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | IGF2BP2 | 3 | 185793899 | G | T |
| rs4402960 | 23690305 | 2645 | GCK | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.144808288 | 2013 | IGF2BP2 | 3 | 185793899 | G | T |
| rs4506565 | 25973943 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Association with GDM was found for two of the most frequently replicated T2D loci: a TCF7L2 haplotype (CTTC: rs7901695, rs4506565, rs7903146, rs12243326; P=2.16 x 10(-06); OR=2.95) and a KCNQ1 haplotype (TTT: rs2237892, rs163184, rs2237897; P=1.98 x 10(-05); OR=0.55). | 0.014254393 | 2015 | TCF7L2 | 10 | 112996282 | A | T |
| rs4994 | 17046546 | 155 | ADRB3 | umls:C0085207 | BeFree | We studied possible relations between GDM and both insulin receptor substrate 1 (IRS-1) (Gly972Arg) and beta3-adrenergic receptor (ADRB3 Trp64Arg, beta3-AR) gene mutations, considered potential modifying factors in the etiology of type 2 diabetes mellitus. | 0.003181358 | 2006 | ADRB3 | 8 | 37966280 | A | G |
| rs4994 | 17342473 | 5468 | PPARG | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.007177041 | 2007 | ADRB3 | 8 | 37966280 | A | G |
| rs4994 | 17342473 | 155 | ADRB3 | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.003181358 | 2007 | ADRB3 | 8 | 37966280 | A | G |
| rs4994 | 15334374 | 155 | ADRB3 | umls:C0085207 | BeFree | Our results indicated that the ADRB3 Trp64Arg variant is not related to the development of GDM and has no effect on obesity during pregnancy in a Taiwanese population. | 0.003181358 | 2004 | ADRB3 | 8 | 37966280 | A | G |
| rs4994 | 17342473 | 10891 | PPARGC1A | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.000542884 | 2007 | ADRB3 | 8 | 37966280 | A | G |
| rs4994 | 17342473 | 2303 | FOXC2 | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.000271442 | 2007 | ADRB3 | 8 | 37966280 | A | G |
| rs4994 | 17342473 | 9370 | ADIPOQ | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.220427661 | 2007 | ADRB3 | 8 | 37966280 | A | G |
| rs5015480 | 19002430 | 3630 | INS | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.023820871 | 2009 | NA | 10 | 92705802 | C | T |
| rs5015480 | 19002430 | 1029 | CDKN2A | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 10 | 92705802 | C | T |
| rs5015480 | 19002430 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.123452799 | 2009 | NA | 10 | 92705802 | C | T |
| rs5015480 | 19002430 | 1030 | CDKN2B | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 10 | 92705802 | C | T |
| rs5015480 | 19002430 | 3087 | HHEX | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 10 | 92705802 | C | T |
| rs5219 | 23690305 | 3767 | KCNJ11 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.009172942 | 2013 | KCNJ11 | 11 | 17388025 | T | C |
| rs5219 | 23690305 | 3667 | IRS1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.005352893 | 2013 | KCNJ11 | 11 | 17388025 | T | C |
| rs5219 | 23690305 | 2645 | GCK | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.144808288 | 2013 | KCNJ11 | 11 | 17388025 | T | C |
| rs5219 | 16320083 | 3767 | KCNJ11 | umls:C0085207 | BeFree | Association of the E23K polymorphism in the KCNJ11 gene with gestational diabetes mellitus. | 0.009172942 | 2005 | KCNJ11 | 11 | 17388025 | T | C |
| rs5219 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | KCNJ11 | 11 | 17388025 | T | C |
| rs5219 | 23690305 | 10644 | IGF2BP2 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.12554839 | 2013 | KCNJ11 | 11 | 17388025 | T | C |
| rs5219 | 23690305 | 4544 | MTNR1B | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.002171535 | 2013 | KCNJ11 | 11 | 17388025 | T | C |
| rs5219 | 23690305 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.123452799 | 2013 | KCNJ11 | 11 | 17388025 | T | C |
| rs560887 | 23761423 | 111 | ADCY5 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | G6PC2 | 2 | 168906638 | T | C |
| rs560887 | 23761423 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.014254393 | 2013 | G6PC2 | 2 | 168906638 | T | C |
| rs560887 | 23761423 | 79068 | FTO | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000542884 | 2013 | G6PC2 | 2 | 168906638 | T | C |
| rs560887 | 23761423 | 7088 | TLE1 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | G6PC2 | 2 | 168906638 | T | C |
| rs560887 | 23761423 | 2646 | GCKR | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | G6PC2 | 2 | 168906638 | T | C |
| rs560887 | 23761423 | 57818 | G6PC2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | G6PC2 | 2 | 168906638 | T | C |
| rs587780343 | NA | 2645 | GCK | umls:C0085207 | CLINVAR | NA | 0.144808288 | NA | GCK | 7 | 44145638 | C | A |
| rs587780345 | NA | 2645 | GCK | umls:C0085207 | CLINVAR | NA | 0.144808288 | NA | GCK;LOC105375258 | 7 | 44150004 | C | T |
| rs587780346 | NA | 2645 | GCK | umls:C0085207 | CLINVAR | NA | 0.144808288 | NA | GCK;LOC105375258 | 7 | 44149823 | T | G |
| rs587780347 | NA | 2645 | GCK | umls:C0085207 | CLINVAR | NA | 0.144808288 | NA | GCK;LOC105375258 | 7 | 44147807 | C | T |
| rs662 | 25036896 | 5444 | PON1 | umls:C0085207 | BeFree | Relationship between the paraoxonase 1 gene glutamine 192 to arginine polymorphism and gestational diabetes mellitus in Saudi women. | 0.000271442 | 2014 | PON1 | 7 | 95308134 | T | C |
| rs738409 | 25646328 | 80339 | PNPLA3 | umls:C0085207 | BeFree | Isoleucine-to-methionine substitution at residue 148 variant of PNPLA3 gene and metabolic outcomes in gestational diabetes. | 0.000271442 | 2015 | PNPLA3 | 22 | 43928847 | C | G |
| rs7754840 | 22096510 | 3630 | INS | umls:C0085207 | BeFree | We also found that the risk alleles of rs2383208 (b = -0.085, p = 0.003), rs4402960 (b = -0.057, p = 0.046) and rs10830963 (b = -0.096, p = 0.001) were associated with HOMA-B, while rs7754840 was associated with decrease in insulin AUC during a 100 g OGTT given at the time of GDM diagnosis (b = -0.080, p = 0.007). | 0.023820871 | 2011 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 22233651 | 54901 | CDKAL1 | umls:C0085207 | GWASCAT | In conclusion, we have confirmed that genetic variants in CDKAL1 and near MTNR1B are strongly associated with GDM in Korean women. | 0.123452799 | 2012 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 19002430 | 1029 | CDKN2A | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 23690305 | 3667 | IRS1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.005352893 | 2013 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 23690305 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.123452799 | 2013 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 19002430 | 3630 | INS | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.023820871 | 2009 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 23690305 | 4544 | MTNR1B | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.002171535 | 2013 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 19002430 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.123452799 | 2009 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 22233651 | 54901 | CDKAL1 | umls:C0085207 | GAD | [In conclusion, we have confirmed that genetic variants in CDKAL1 and near MTNR1B are strongly associated with GDM in Korean women.] | 0.123452799 | 2012 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 19002430 | 3087 | HHEX | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 23690305 | 2645 | GCK | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.144808288 | 2013 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 23690305 | 3767 | KCNJ11 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.009172942 | 2013 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 19002430 | 1030 | CDKN2B | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7754840 | 23690305 | 10644 | IGF2BP2 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.12554839 | 2013 | CDKAL1 | 6 | 20661019 | G | C,T |
| rs7756992 | 19002430 | 1030 | CDKN2B | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | CDKAL1 | 6 | 20679478 | A | G |
| rs7756992 | 19002430 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.123452799 | 2009 | CDKAL1 | 6 | 20679478 | A | G |
| rs7756992 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | CDKAL1 | 6 | 20679478 | A | G |
| rs7756992 | 19002430 | 1029 | CDKN2A | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | CDKAL1 | 6 | 20679478 | A | G |
| rs7756992 | 19002430 | 3630 | INS | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.023820871 | 2009 | CDKAL1 | 6 | 20679478 | A | G |
| rs7756992 | 19002430 | 3087 | HHEX | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | CDKAL1 | 6 | 20679478 | A | G |
| rs780094 | 23761423 | 111 | ADCY5 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | GCKR | 2 | 27518370 | T | C |
| rs780094 | 23761423 | 79068 | FTO | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000542884 | 2013 | GCKR | 2 | 27518370 | T | C |
| rs780094 | 23761423 | 7088 | TLE1 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | GCKR | 2 | 27518370 | T | C |
| rs780094 | 23761423 | 57818 | G6PC2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | GCKR | 2 | 27518370 | T | C |
| rs780094 | 23456907 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Among Caucasian women, GDM was associated with carriage of TCF7L2 rs7901695, MTNR1B rs10830963 and GCKR rs780094 alleles that are associated with T2DM and fasting glucose in nonpregnant populations. | 0.014254393 | 2014 | GCKR | 2 | 27518370 | T | C |
| rs780094 | 23761423 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.014254393 | 2013 | GCKR | 2 | 27518370 | T | C |
| rs780094 | 23761423 | 2646 | GCKR | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | GCKR | 2 | 27518370 | T | C |
| rs7901695 | 23456907 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Among Caucasian women, GDM was associated with carriage of TCF7L2 rs7901695, MTNR1B rs10830963 and GCKR rs780094 alleles that are associated with T2DM and fasting glucose in nonpregnant populations. | 0.014254393 | 2014 | TCF7L2 | 10 | 112994329 | T | C |
| rs7901695 | 25973943 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Association with GDM was found for two of the most frequently replicated T2D loci: a TCF7L2 haplotype (CTTC: rs7901695, rs4506565, rs7903146, rs12243326; P=2.16 x 10(-06); OR=2.95) and a KCNQ1 haplotype (TTT: rs2237892, rs163184, rs2237897; P=1.98 x 10(-05); OR=0.55). | 0.014254393 | 2015 | TCF7L2 | 10 | 112994329 | T | C |
| rs7903146 | 23761423 | 2646 | GCKR | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 25973943 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Association with GDM was found for two of the most frequently replicated T2D loci: a TCF7L2 haplotype (CTTC: rs7901695, rs4506565, rs7903146, rs12243326; P=2.16 x 10(-06); OR=2.95) and a KCNQ1 haplotype (TTT: rs2237892, rs163184, rs2237897; P=1.98 x 10(-05); OR=0.55). | 0.014254393 | 2015 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23761423 | 111 | ADCY5 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23761423 | 57818 | G6PC2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 22591707 | 79068 | FTO | umls:C0085207 | BeFree | The TCF7L2 rs7903146 and FTO rs8050136 polymorphisms, and particularly a weighted risk score of T2D risk alleles, predict diabetes after GDM. | 0.000542884 | 2012 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23690305 | 3667 | IRS1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.005352893 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 20540670 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Thus, our data suggest that the common T2D susceptibility polymorphism of TCF7L2 (rs7903146 C/T) gene, and the G972R polymorphism of the IRS1 gene, seem to predispose to GDM in Greek women. | 0.014254393 | 2011 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23690305 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.123452799 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23690305 | 2645 | GCK | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.144808288 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23761423 | 79068 | FTO | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000542884 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23761423 | 7088 | TLE1 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23690305 | 4544 | MTNR1B | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.002171535 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23690305 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Among them, genetic variants in TCF7L2 showed the strongest association with GDM risk, with ORs (95% CIs) of 1.44 (1.29-1.60, P < 0.001) per T allele of rs7903146 and 1.46 (1.15-1.84, P = 0.002) per T allele of rs12255372. | 0.014254393 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23855352 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Association of the rs7903146 polymorphism in transcription factor 7-like 2 (TCF7L2) gene with gestational diabetes mellitus: a meta-analysis. | 0.014254393 | 2014 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23690305 | 3767 | KCNJ11 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.009172942 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23761423 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.014254393 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 23690305 | 10644 | IGF2BP2 | umls:C0085207 | BeFree | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K, KCNJ11), rs7754840 (CDKAL1), rs4402960 (IGF2BP2), rs10830963 (MTNR1B), rs1387153 (MTNR1B) and rs1801278 (Gly972Arg, IRS1) were significantly associated with a higher risk of GDM. | 0.12554839 | 2013 | TCF7L2 | 10 | 112998590 | C | T |
| rs7903146 | 20540670 | 3667 | IRS1 | umls:C0085207 | BeFree | Thus, our data suggest that the common T2D susceptibility polymorphism of TCF7L2 (rs7903146 C/T) gene, and the G972R polymorphism of the IRS1 gene, seem to predispose to GDM in Greek women. | 0.005352893 | 2011 | TCF7L2 | 10 | 112998590 | C | T |
| rs7923837 | 19002430 | 1030 | CDKN2B | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 10 | 92722160 | G | A |
| rs7923837 | 19002430 | 1029 | CDKN2A | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 10 | 92722160 | G | A |
| rs7923837 | 19002430 | 3630 | INS | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.023820871 | 2009 | NA | 10 | 92722160 | G | A |
| rs7923837 | 19002430 | 54901 | CDKAL1 | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.123452799 | 2009 | NA | 10 | 92722160 | G | A |
| rs7923837 | 19002430 | 3087 | HHEX | umls:C0085207 | BeFree | The risk alleles of the SNPs rs7756992 and rs7754840 in CDKAL1; rs10811661 in the CDKN2A-CDKN2B region; and rs1111875, rs5015480 and rs7923837 in HHEX were associated with significant decreases in the insulin AUC during a 100 g OGTT performed at the time of diagnosis of GDM. | 0.000271442 | 2009 | NA | 10 | 92722160 | G | A |
| rs8050136 | 22591707 | 3767 | KCNJ11 | umls:C0085207 | BeFree | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs1169288, and KCNJ11 rs5219) were genotyped in 793 women with GDM after a median follow-up of 57 months. | 0.009172942 | 2012 | FTO | 16 | 53782363 | C | A |
| rs8050136 | 22591707 | 79068 | FTO | umls:C0085207 | BeFree | The TCF7L2 rs7903146 and FTO rs8050136 polymorphisms, and particularly a weighted risk score of T2D risk alleles, predict diabetes after GDM. | 0.000542884 | 2012 | FTO | 16 | 53782363 | C | A |
| rs8111699 | 23706335 | 6794 | STK11 | umls:C0085207 | BeFree | In pregnant women, the G allele for the rs8111699 variant in STK11 is associated with a more favorable metabolic phenotype and may protect against the development of GDM, particularly in heavier women. | 0.000271442 | 2013 | STK11 | 19 | 1209715 | C | G |
| rs8192678 | 17342473 | 2303 | FOXC2 | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.000271442 | 2007 | PPARGC1A | 4 | 23814039 | C | T |
| rs8192678 | 17342473 | 5468 | PPARG | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.007177041 | 2007 | PPARGC1A | 4 | 23814039 | C | T |
| rs8192678 | 17342473 | 10891 | PPARGC1A | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.000542884 | 2007 | PPARGC1A | 4 | 23814039 | C | T |
| rs8192678 | 17342473 | 155 | ADRB3 | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.003181358 | 2007 | PPARGC1A | 4 | 23814039 | C | T |
| rs8192678 | 17342473 | 9370 | ADIPOQ | umls:C0085207 | BeFree | The other polymorphisms studied were not significantly associated with gestational diabetes mellitus (ADIPOQ +276G > T: 1.17 [1.01-1.36], p = 0.039 [Pc = 0.23]; PPARG Pro12Ala: 1.06 [0.87-1.29], p = 0.53; PPARGC1A Gly482Ser: 0.96 [0.83-1.10], p = 0.54; FOXC2 -512C > T: 1.01 [0.87-1.16], p = 0.94; and ADRB3 Trp64Arg: 1.22 [0.95-1.56], p = 0.12). | 0.220427661 | 2007 | PPARGC1A | 4 | 23814039 | C | T |
| rs9939609 | 23761423 | 7088 | TLE1 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | FTO | 16 | 53786615 | T | A |
| rs9939609 | 23761423 | 57818 | G6PC2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | FTO | 16 | 53786615 | T | A |
| rs9939609 | 23761423 | 2646 | GCKR | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | FTO | 16 | 53786615 | T | A |
| rs9939609 | 23761423 | 79068 | FTO | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000542884 | 2013 | FTO | 16 | 53786615 | T | A |
| rs9939609 | 23761423 | 6934 | TCF7L2 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.014254393 | 2013 | FTO | 16 | 53786615 | T | A |
| rs9939609 | 23761423 | 111 | ADCY5 | umls:C0085207 | BeFree | Additionally, risk variants rs9939609 of FTO, rs2796441 of TLE1, rs560887 of G6PC2, rs780094 of GCKR, rs7903146 of TCF7L2 and rs11708067 of ADCY5 showed nominally significant associations with GDM (OR range from 1.25 to 1.30). | 0.000271442 | 2013 | FTO | 16 | 53786615 | T | A |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:47) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 1 | 5782769 | rs2649086 | T | C | rs2649086 | 22233651 | 8.96E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | NA |
| 1 | 18722737 | rs1336131 | G | T | rs1336131 | 22233651 | 5.74E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | NA |
| 1 | 65135341 | rs7513574 | G | T | rs7513574 | 22233651 | 1.75E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | CACHD1 |
| 1 | 92177062 | rs17512269 | C | T | rs17512269 | 22233651 | 5.82E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | TGFBR3 |
| 2 | 41535003 | rs13415944 | G | C | rs13415944 | 22233651 | 2.89E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | NA |
| 2 | 199753674 | rs12614240 | C | T | rs12614240 | 22233651 | 2.40E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | NA |
| 3 | 26775763 | rs1386886 | C | T | rs1386886 | 22233651 | 2.14E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | A | NA |
| 3 | 26778370 | rs9866020 | G | A | rs9866020 | 22233651 | 5.27E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | A | NA |
| 3 | 26843377 | rs1155107 | A | G | rs1155107 | 22233651 | 6.37E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | NA | NA |
| 3 | 26847785 | rs9848111 | A | G | rs9848111 | 22233651 | 2.47E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | NA |
| 3 | 35794900 | rs9865772 | C | T | rs9865772 | 22233651 | 6.13E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | ARPP21 |
| 3 | 66868609 | rs10049466 | C | T | rs10049466 | 22233651 | 9.66E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | NA |
| 3 | 171270483 | rs360457 | G | T | rs360457 | 22233651 | 3.02E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | NA |
| 3 | 185497635 | rs4376068 | A | C | rs4376068 | 22233651 | 6.37E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | IGF2BP2 |
| 3 | 185499057 | rs6801848 | C | G | rs6801848 | 22233651 | 1.00E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | IGF2BP2 |
| 3 | 185511687 | rs4402960 | G | T | rs4402960 | 22233651 | 7.72E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | IGF2BP2 |
| 3 | 185513392 | rs7651090 | A | G | rs7651090 | 22233651 | 2.47E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | IGF2BP2 |
| 3 | 185529080 | rs1470579 | A | C | rs1470579 | 22233651 | 2.00E-07 | NA | 1.33 | [1.20-1.48] | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | rs1470579-C | Research Support, Non-U.S. Gov't | C | IGF2BP2 |
| 5 | 173160684 | rs10071956 | T | C | rs10071956 | 22233651 | 5.92E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | NA |
| 5 | 173165659 | rs4868311 | T | C | rs4868311 | 22233651 | 5.08E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | NA |
| 5 | 173753469 | rs2913472 | C | A | rs2913472 | 22233651 | 2.89E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | A | NA |
| 6 | 20570039 | rs4291090 | C | T | rs4291090 | 22233651 | 5.01E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | CDKAL1 |
| 6 | 20599628 | rs9366357 | C | T | rs9366357 | 22233651 | 2.96E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | CDKAL1 |
| 6 | 20599888 | rs2294809 | C | T | rs2294809 | 22233651 | 1.90E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | CDKAL1 |
| 6 | 20639604 | rs7758612 | G | A | rs7758612 | 22233651 | 1.32E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | A | CDKAL1 |
| 6 | 20641336 | rs9348440 | C | T | rs9348440 | 22233651 | 4.01E-10 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | CDKAL1 |
| 6 | 20659806 | rs6456368 | T | C | rs6456368 | 22233651 | 3.46E-11 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | CDKAL1 |
| 6 | 20661034 | rs10946398 | A | C | rs10946398 | 22233651 | 1.76E-10 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | CDKAL1 |
| 6 | 20661250 | rs7754840 | G | C | rs7754840 | 22233651 | 7.00E-16 | NA | 1.52 | [1.37-1.68] | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | rs7754840-C | Research Support, Non-U.S. Gov't | G | CDKAL1 |
| 6 | 20717255 | rs9465871 | T | C | rs9465871 | 22233651 | 1.14E-07 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | CDKAL1 |
| 6 | 20718240 | rs2328549 | A | T | rs2328549 | 22233651 | 4.78E-08 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | A | CDKAL1 |
| 6 | 20725240 | rs7767391 | T | C | rs7767391 | 22233651 | 8.25E-09 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | CDKAL1 |
| 6 | 54247467 | rs1508635 | A | C | rs1508635 | 22233651 | 2.73E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | TINAG |
| 9 | 73164637 | rs2277188 | C | T | rs2277188 | 22233651 | 5.06E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | TRPM3 |
| 9 | 119392413 | rs1885245 | G | C | rs1885245 | 22233651 | 8.61E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | ASTN2 |
| 10 | 63613870 | rs10821926 | T | C | rs10821926 | 22233651 | 5.30E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | NA |
| 10 | 68125841 | rs7914106 | T | G | rs7914106 | 22233651 | 9.59E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | CTNNA3 |
| 11 | 62237317 | rs2513044 | A | G | rs2513044 | 22233651 | 5.69E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | AHNAK |
| 11 | 92698427 | rs10830962 | C | G | rs10830962 | 22233651 | 2.00E-13 | NA | 1.45 | [1.31-1.61] | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | rs10830962-G | Research Support, Non-U.S. Gov't | G | NA |
| 13 | 94209956 | rs9524131 | T | C | rs9524131 | 22233651 | 2.66E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | GPC6 |
| 13 | 110995528 | rs9559772 | C | G | rs9559772 | 22233651 | 4.14E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | COL4A2 |
| 14 | 99858970 | rs1257267 | C | A | rs1257267 | 22233651 | 8.55E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | NA |
| 15 | 68128117 | rs12898654 | C | G | rs12898654 | 22233651 | 4.37E-06 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | NA |
| 16 | 71207879 | rs9939485 | G | C | rs9939485 | 22233651 | 3.55E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | HYDIN |
| 16 | 87957458 | rs7499404 | T | C | rs7499404 | 22233651 | 8.88E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | T | CA5A |
| 19 | 2242829 | rs7249235 | A | C | rs7249235 | 22233651 | 8.55E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | C | SF3A2 |
| 20 | 44401404 | rs800684 | C | G | rs800684 | 22233651 | 9.62E-05 | NA | NA | NA | 468 cases of Korean ancestry; 1,242 controls of Korean ancestry | Korean(1710) | ALL(1710) | ASN(1710) | ALL(1710) | Diabetes (gestational) | HPOID:0009800 | Maternal diabetes | DOID:11714 | gestational diabetes | D016640 | Diabetes, Gestational | EFOID:0004593 | gestational diabetes | Gestational diabetes | NA | Research Support, Non-U.S. Gov't | G | NA |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:3) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0085207 | glutathione | D005978 | 70-18-8 | diabetes, gestational | MESH:D016640 | marker/mechanism | 23956348 | ||
| C0085207 | metformin | D008687 | 657-24-9 | diabetes, gestational | MESH:D016640 | therapeutic | 23457588 | ||
| C0085207 | prochlorperazine | D011346 | 58-38-8 | diabetes, gestational | MESH:D016640 | marker/mechanism | 18480684 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |