PedAM

Pediatric Disease Annotations & Medicines


	generalized anxiety disorder

Disease ID	807
Disease	generalized anxiety disorder
Definition	A condition marked by excessive worry and feelings of fear, dread, and uneasiness that last six months or longer. Other symptoms of GAD include being restless, being tired or irritable, muscle tension, not being able to concentrate or sleep well, shortness of breath, fast heartbeat, sweating, and dizziness.
Synonym	anxiety disorder generalize anxiety disorder generalized anxiety disorders generalized gad gad - generalised anxiety disorder gad - generalized anxiety disorder gads generalised anxiety disorder generalised anxiety disorder (disorder) generalised anxiety disorder [ambiguous] generalized anxiety dis generalized anxiety disorder (disorder) generalized anxiety disorders
OMIM	OMIM:605363 OMIM:604518
DOID	DOID:14320
ICD10	ICD10CM:F41.1
UMLS	C0270549
SNOMED-CT	SNOMEDCT_US_2016_09_01:21897009
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:28) C0003467 \| anxiety \| 14 C0001818 \| agoraphobia \| 13 C0011570 \| depression \| 9 C0003469 \| anxiety disorder \| 5 C0003469 \| anxiety disorders \| 4 C0030319 \| panic disorder \| 3 C0041696 \| major depressive disorder \| 3 C0041696 \| major depression \| 2 C0006325 \| bruxism \| 2 C0031572 \| social phobia \| 2 C0012236 \| 22q11.2 deletion syndrome \| 1 C0795690 \| omphalocele \| 1 C0037317 \| sleep disturbance \| 1 C0018799 \| heart disease \| 1 C0236801 \| specific phobia \| 1 C0019196 \| hepatitis c \| 1 C0032460 \| polycystic ovary syndrome \| 1 C0032460 \| polycystic ovary \| 1 C0236792 \| asperger's disorder \| 1 C0040128 \| thyroid disorders \| 1 C0851578 \| sleep disorders \| 1 C0013395 \| dyspepsia \| 1 C0013415 \| dysthymic disorder \| 1 C0019158 \| hepatitis \| 1 C0038436 \| posttraumatic stress disorder \| 1 C0948265 \| metabolic syndrome \| 1 C0037317 \| sleep disturbances \| 1 C0010068 \| coronary heart disease \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:2) GRAP2 \| 9402 \| OMIM GAD1 \| 2571 \| OMIM
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:151) 4710 \| NDUFB4 \| DISEASES 27248 \| ERLEC1 \| DISEASES 6530 \| SLC6A2 \| DISEASES 1158 \| CKM \| DISEASES 41 \| ASIC1 \| DISEASES 55907 \| CMAS \| DISEASES 23438 \| HARS2 \| DISEASES 2908 \| NR3C1 \| DISEASES 11334 \| TUSC2 \| DISEASES 5997 \| RGS2 \| DISEASES 134637 \| ADAT2 \| DISEASES 140735 \| DYNLL2 \| DISEASES 7291 \| TWIST1 \| DISEASES 5552 \| SRGN \| DISEASES 5184 \| PEPD \| DISEASES 5880 \| RAC2 \| DISEASES 7166 \| TPH1 \| DISEASES 8220 \| DGCR14 \| DISEASES 7136 \| TNNI2 \| DISEASES 9113 \| LATS1 \| DISEASES 8572 \| PDLIM4 \| DISEASES 55145 \| THAP1 \| DISEASES 51540 \| SCLY \| DISEASES 1401 \| CRP \| DISEASES 3357 \| HTR2B \| DISEASES 2572 \| GAD2 \| DISEASES 6519 \| SLC3A1 \| DISEASES 9360 \| PPIG \| DISEASES 3093 \| UBE2K \| DISEASES 6532 \| SLC6A4 \| DISEASES 4969 \| OGN \| DISEASES 2033 \| EP300 \| DISEASES 8452 \| CUL3 \| DISEASES 51665 \| ASB1 \| DISEASES 5443 \| POMC \| DISEASES 64083 \| GOLPH3 \| DISEASES 55749 \| CCAR1 \| DISEASES 56938 \| ARNTL2 \| DISEASES 93650 \| ACPT \| DISEASES 3756 \| KCNH1 \| DISEASES 3358 \| HTR2C \| DISEASES 1392 \| CRH \| DISEASES 5047 \| PAEP \| DISEASES 150 \| ADRA2A \| DISEASES 51594 \| NBAS \| DISEASES 55079 \| FEZF2 \| DISEASES 6529 \| SLC6A1 \| DISEASES 4681 \| NBL1 \| DISEASES 2560 \| GABRB1 \| DISEASES 50852 \| TRAT1 \| DISEASES 6632 \| SNRPD1 \| DISEASES 6786 \| STIM1 \| DISEASES 4054 \| LTBP3 \| DISEASES 116844 \| LRG1 \| DISEASES 140738 \| TMEM37 \| DISEASES 51181 \| DCXR \| DISEASES 6869 \| TACR1 \| DISEASES 1816 \| DRD5 \| DISEASES 255239 \| ANKK1 \| DISEASES 1501 \| CTNND2 \| DISEASES 134 \| ADORA1 \| DISEASES 51172 \| NAGPA \| DISEASES 10713 \| USP39 \| DISEASES 3352 \| HTR1D \| DISEASES 3350 \| HTR1A \| DISEASES 147912 \| SIX5 \| DISEASES 4026 \| LPP \| DISEASES 10938 \| EHD1 \| DISEASES 6863 \| TAC1 \| DISEASES 7156 \| TOP3A \| DISEASES 23017 \| FAIM2 \| DISEASES 5021 \| OXTR \| DISEASES 1812 \| DRD1 \| DISEASES 5074 \| PAWR \| DISEASES 706 \| TSPO \| DISEASES 277 \| AMY1B \| DISEASES 5136 \| PDE1A \| DISEASES 170392 \| OIT3 \| DISEASES 887 \| CCKBR \| DISEASES 3988 \| LIPA \| DISEASES 64359 \| NXN \| DISEASES 3363 \| HTR7 \| DISEASES 9402 \| GRAP2 \| DISEASES 6540 \| SLC6A13 \| DISEASES 4128 \| MAOA \| DISEASES 1395 \| CRHR2 \| DISEASES 1544 \| CYP1A2 \| DISEASES 1508 \| CTSB \| DISEASES 132884 \| EVC2 \| DISEASES 10166 \| SLC25A15 \| DISEASES 5348 \| FXYD1 \| DISEASES 23481 \| PES1 \| DISEASES 3359 \| HTR3A \| DISEASES 5979 \| RET \| DISEASES 51114 \| ZDHHC9 \| DISEASES 2571 \| GAD1 \| DISEASES 8936 \| WASF1 \| DISEASES 6539 \| SLC6A12 \| DISEASES 387129 \| NPSR1 \| DISEASES 1066 \| CES1 \| DISEASES 11169 \| WDHD1 \| DISEASES 1565 \| CYP2D6 \| DISEASES 5167 \| ENPP1 \| DISEASES 1312 \| COMT \| DISEASES 4860 \| PNP \| DISEASES 1813 \| DRD2 \| DISEASES 7058 \| THBS2 \| DISEASES 2058 \| EPRS \| DISEASES 5362 \| PLXNA2 \| DISEASES 2494 \| NR5A2 \| DISEASES 4014 \| LOR \| DISEASES 3713 \| IVL \| DISEASES 3351 \| HTR1B \| DISEASES 278 \| AMY1C \| DISEASES 276 \| AMY1A \| DISEASES 115004 \| MB21D1 \| DISEASES 81030 \| ZBP1 \| DISEASES 11128 \| POLR3A \| DISEASES 79717 \| PPCS \| DISEASES 23569 \| PADI4 \| DISEASES 1325 \| CORT \| DISEASES 4129 \| MAOB \| DISEASES 3356 \| HTR2A \| DISEASES 2625 \| GATA3 \| DISEASES 146 \| ADRA1D \| DISEASES 148 \| ADRA1A \| DISEASES 1814 \| DRD3 \| DISEASES 9901 \| SRGAP3 \| DISEASES 3426 \| CFI \| DISEASES 5660 \| PSAP \| DISEASES 2912 \| GRM2 \| DISEASES 1394 \| CRHR1 \| DISEASES 210 \| ALAD \| DISEASES 9048 \| ARTN \| DISEASES 348180 \| CTU2 \| DISEASES 65250 \| C5orf42 \| DISEASES 23210 \| JMJD6 \| DISEASES 10163 \| WASF2 \| DISEASES 8910 \| SGCE \| DISEASES 6635 \| SNRPE \| DISEASES 9278 \| ZBTB22 \| DISEASES 83871 \| RAB34 \| DISEASES 389549 \| FEZF1 \| DISEASES 627 \| BDNF \| DISEASES 3035 \| HARS \| DISEASES 54970 \| TTC12 \| DISEASES 4925 \| NUCB2 \| DISEASES 5715 \| PSMD9 \| DISEASES 169355 \| IDO2 \| DISEASES 91056 \| AP5B1 \| DISEASES 4782 \| NFIC \| DISEASES
Locus	(Waiting for update.)

Disease ID	807
Disease	generalized anxiety disorder
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:17) HP:0000739 \| Anxiety \| 14 HP:0000756 \| Fear of open spaces \| 13 HP:0000716 \| Depression \| 9 HP:0003763 \| Bruxism \| 2 HP:0011675 \| Arrhythmias \| 1 HP:0001539 \| Omphalocele \| 1 HP:0001397 \| Hepatic steatosis \| 1 HP:0000360 \| Ringing in the ears \| 1 HP:0002315 \| Headaches \| 1 HP:0012115 \| Liver inflammation \| 1 HP:0000147 \| Sclerocystic ovaries \| 1 HP:0001511 \| Prenatal onset growth retardation \| 1 HP:0100710 \| Impulsivity \| 1 HP:0000708 \| Behavioral problems \| 1 HP:0002500 \| Leukoaraiosis \| 1 HP:0002360 \| Sleep disturbance \| 1 HP:0100543 \| Cognitive deficits \| 1

Disease ID	807
Disease	generalized anxiety disorder
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:1) C0011570 \| depression \| 9

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:12)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs12454712	20122683	596	BCL2	umls:C0270549	BeFree	BCL2 rs12454712 (p = .0029) and DRD2 rs4245146 (p = .0010) showed evidence for association to generalized anxiety disorder, whereas rs2463107 (p = .0064) in PAWR and rs4245146 (p = .0029) in DRD2 showed evidence for association to the pooled group of all anxiety disorders.	0.000271442	2010	BCL2	18	63178651	T	C
rs12454712	20122683	5074	PAWR	umls:C0270549	BeFree	BCL2 rs12454712 (p = .0029) and DRD2 rs4245146 (p = .0010) showed evidence for association to generalized anxiety disorder, whereas rs2463107 (p = .0064) in PAWR and rs4245146 (p = .0029) in DRD2 showed evidence for association to the pooled group of all anxiety disorders.	0.000271442	2010	BCL2	18	63178651	T	C
rs12454712	20122683	1813	DRD2	umls:C0270549	BeFree	BCL2 rs12454712 (p = .0029) and DRD2 rs4245146 (p = .0010) showed evidence for association to generalized anxiety disorder, whereas rs2463107 (p = .0064) in PAWR and rs4245146 (p = .0029) in DRD2 showed evidence for association to the pooled group of all anxiety disorders.	0.000542884	2010	BCL2	18	63178651	T	C
rs2463107	20122683	1813	DRD2	umls:C0270549	BeFree	BCL2 rs12454712 (p = .0029) and DRD2 rs4245146 (p = .0010) showed evidence for association to generalized anxiety disorder, whereas rs2463107 (p = .0064) in PAWR and rs4245146 (p = .0029) in DRD2 showed evidence for association to the pooled group of all anxiety disorders.	0.000542884	2010	NA	12	79699537	A	C
rs2463107	20122683	596	BCL2	umls:C0270549	BeFree	BCL2 rs12454712 (p = .0029) and DRD2 rs4245146 (p = .0010) showed evidence for association to generalized anxiety disorder, whereas rs2463107 (p = .0064) in PAWR and rs4245146 (p = .0029) in DRD2 showed evidence for association to the pooled group of all anxiety disorders.	0.000271442	2010	NA	12	79699537	A	C
rs2463107	20122683	5074	PAWR	umls:C0270549	BeFree	BCL2 rs12454712 (p = .0029) and DRD2 rs4245146 (p = .0010) showed evidence for association to generalized anxiety disorder, whereas rs2463107 (p = .0064) in PAWR and rs4245146 (p = .0029) in DRD2 showed evidence for association to the pooled group of all anxiety disorders.	0.000271442	2010	NA	12	79699537	A	C
rs386602276	11444684	3356	HTR2A	umls:C0270549	BeFree	The authors tested for association of the 5-HT2A receptor polymorphism (T102C) and the intron 7 tryptophan hydroxylase (TPH) polymorphism (A218C) among 176 alcohol dependent patients, 35 patients with panic disorder, 50 patients with generalized anxiety disorder, 55 patients with narcolepsy and 87 healthy controls.	0.000814326	2001	NA	NA	NA	NA	NA
rs4245146	20122683	596	BCL2	umls:C0270549	BeFree	BCL2 rs12454712 (p = .0029) and DRD2 rs4245146 (p = .0010) showed evidence for association to generalized anxiety disorder, whereas rs2463107 (p = .0064) in PAWR and rs4245146 (p = .0029) in DRD2 showed evidence for association to the pooled group of all anxiety disorders.	0.000271442	2010	DRD2	11	113447251	T	C
rs4245146	20122683	5074	PAWR	umls:C0270549	BeFree	BCL2 rs12454712 (p = .0029) and DRD2 rs4245146 (p = .0010) showed evidence for association to generalized anxiety disorder, whereas rs2463107 (p = .0064) in PAWR and rs4245146 (p = .0029) in DRD2 showed evidence for association to the pooled group of all anxiety disorders.	0.000271442	2010	DRD2	11	113447251	T	C
rs4245146	20122683	1813	DRD2	umls:C0270549	BeFree	BCL2 rs12454712 (p = .0029) and DRD2 rs4245146 (p = .0010) showed evidence for association to generalized anxiety disorder, whereas rs2463107 (p = .0064) in PAWR and rs4245146 (p = .0029) in DRD2 showed evidence for association to the pooled group of all anxiety disorders.	0.000542884	2010	DRD2	11	113447251	T	C
rs4792888	22249355	1394	CRHR1	umls:C0270549	BeFree	Only rs4792888 in CRHR1 showed modest evidence of association with duloxetine response in MDD (P=0.029 in GAD, P=0.054 in MDD).	0.000542884	2013	CRHR1;MGC57346-CRHR1	17	45800588	A	G
rs6313	11444684	3356	HTR2A	umls:C0270549	BeFree	The authors tested for association of the 5-HT2A receptor polymorphism (T102C) and the intron 7 tryptophan hydroxylase (TPH) polymorphism (A218C) among 176 alcohol dependent patients, 35 patients with panic disorder, 50 patients with generalized anxiety disorder, 55 patients with narcolepsy and 87 healthy controls.	0.000814326	2001	HTR2A	13	46895805	G	A

GWASdb Annotation(Total Genotypes:10)
Chr	Pos	SNP_Id	RefGene	EnsemblGene	ENCODE_Factor	ENCODE_TFBS	Chromosome_interaction	GTEx_eQTL	SNP_TFBS_affinity_GWAS3D	SNP_miRNA_target_affinity_PolymiRTS	SNP_splicing_effect_Skippy	SNP_splicing_effect_MutPred_Splice	SNP_ns_protein_effect_dbNSFP	SNP_syn_effect_Silva	SNP_phosphorylation_effect_PhosSNP	PhastCons_score	PhyloP_score	GERP++_RS	Segway_state	Ancestral_allele	ESP_AF	ESP_AFR	ESP_AFR	ESP_EUR	TG_ASN	TG_AMR	TG_AFR	TG_EUR	Type	Consequence	bStatistic	EncH3K27Ac	EncH3K4Me1	EncH3K4Me3	EncNucleo	OMIM	Clinvar
2	171688593	rs10191129	NM_000817,GAD1	NM_013445,GAD1	ENST00000358196,ENSG00000128683	ENST00000375273,ENSG00000128683	ENST00000493875,ENSG00000128683	ENST00000414527,ENSG00000128683	ENST00000375272,ENSG00000128683	ENST00000344257,ENSG00000128683	ENST00000429023,ENSG00000128683	ENST00000493270,ENSG00000128683	MCV-2	NA	chr2,171680001,171690000,chr9,44590001,44600000,18,Hi-C	NA	Cha4-primary,3.4605	Cutl1_3494,1.4168	Gln3-primary,1.544	Gzf3-primary,1.9512	Hoxc13_3127,1.3052	NA	NA	NA	NA	NA	NA	0.038	0.380	1.43	GM0	C	NA	NA	NA	NA	NA
2	171695070	rs3791853	NM_000817,GAD1	NM_013445,GAD1	ENST00000358196,ENSG00000128683	ENST00000375273,ENSG00000128683	ENST00000493875,ENSG00000128683	ENST00000414527,ENSG00000128683	ENST00000375272,ENSG00000128683	ENST00000344257,ENSG00000128683	ENST00000429023,ENSG00000128683	NA	NA	chr2,171690001,171700000,chr12,88780001,88790000,4,Hi-C	chr2,171690001,171700000,chr2,172330001,172340000,5,Hi-C	chr2,171690001,171700000,chr14,39570001,39580000,6,Hi-C	NA	Lys14-primary,1.4423	Pho2-DBD-primary,3.5931	Smp1-primary,4.7276	Yrm1-primary,2.1908	Yrr1-FL-primary,1.4803	NA	NA	NA	NA	NA	NA	0.000	-0.344	-2.13	R4	G	NA	NA	NA	NA
22	40303934	rs137963	NM_004810,GRAP2	ENST00000344138,ENSG00000100351	MCV-4	TFP.USF2	NA	chr22,40300001,40310000,chr22,40930001,40940000,7,Hi-C	chr22,40300001,40310000,chr10,37260001,37270000,8,Hi-C	chr22,40300001,40310000,chr2,61030001,61040000,8,Hi-C	NA	LM90,1.4251	LM90,1.5106	LM120,2.0575	LM128,1.3303	Arnt,10.7157	NA	NA	NA	NA	NA	NA	0.000	-1.984	-4.81	GM1	C	NA	NA	NA	NA	NA	NA	NA	NA	Transcript	INTRONIC
22	40320361	rs137977	NM_004810,GRAP2	ENST00000344138,ENSG00000100351	NA	NA	NA	NA	Cutl1_3494,3.842	Cutl1_3494,7.3201	Hoxa5_3415,5.0077	Hoxc8_3429,10.1588	Rsc3-primary,1.9231	NA	NA	NA	NA	NA	NA	0.000	-0.014	0.112	TF2	A	NA	NA	NA	0.600	0.740	0.470	0.840	0.420	Transcript	INTRONIC	667	1.08	5.64
22	40336845	rs137989	NM_004810,GRAP2	ENST00000344138,ENSG00000100351	ENST00000420971,ENSG00000100351	ENST00000478445,ENSG00000100351	ENST00000461082,ENSG00000100351	MCV-4	TFP.RAD21	TFP.SMC3	TFP.CTCF	NA	NA	NA	Pax-5,3.683	Cart-1,1.6686	HTF,9.003	RFX,5.1188	FOXP3,3.726	NA	NA	NA	NA	NA	NA	0.001	0.910	2.93	C1	T	NA	NA	NA	NA	NA	NA	NA
22	40340775	rs137991	NM_004810,GRAP2	ENST00000344138,ENSG00000100351	ENST00000420971,ENSG00000100351	ENST00000478445,ENSG00000100351	ENST00000461082,ENSG00000100351	NA	NA	chr22,40340001,40350000,chr9,113170001,113180000,6,Hi-C	chr22,40340001,40350000,chr10,81960001,81970000,7,Hi-C	chr22,40340001,40350000,chr12,69000001,69010000,6,Hi-C	chr22,40340001,40350000,chr15,74640001,74650000,9,Hi-C	NA	Gal4-primary,1.3497	Gal4-primary,1.3403	Lhx6_2272,2.3444	Rph1-primary,1.7391	LM134,2.2951	NA	NA	NA	NA	NA	NA	0.001	0.199	0.926	E/GM	T	NA	NA	NA	NA	NA	NA	NA
22	40348520	rs2267420	NM_004810,GRAP2	ENST00000344138,ENSG00000100351	ENST00000420971,ENSG00000100351	ENST00000478445,ENSG00000100351	ENST00000407075,ENSG00000100351	MCV-4	NA	chr22,40340001,40350000,chr9,113170001,113180000,6,Hi-C	chr22,40340001,40350000,chr10,81960001,81970000,7,Hi-C	chr22,40340001,40350000,chr12,69000001,69010000,6,Hi-C	chr22,40340001,40350000,chr15,74640001,74650000,9,Hi-C	NA	Cha4-primary,1.5884	Mig2-primary,1.5883	Mig3-primary,1.3813	Pbf1-primary,1.6666	Pbf2-primary,2.4298	NA	NA	NA	NA	NA	NA	0.000	-0.710	-4.36	GM1	A	NA	NA	NA	0.110	0.120	0.110	0.020
22	40357667	rs9611234	NM_004810,GRAP2	ENST00000344138,ENSG00000100351	ENST00000478445,ENSG00000100351	ENST00000407075,ENSG00000100351	ENST00000424496,ENSG00000225528	TFP.CEBPB	TFP.STAT3	TFP.TCF12	TFP.FOSL1	TFP.EP300	TFP.JUND	TFP.MAX	CHMM	TFP.HDAC2	TFP.JUN	TFP.E2F6	TFP.FOS	TFP.JUNB	TFP.MYC	TFP.PAX5	TFP.MAFK	TFP.IRF4	TFP.BCL11A	TFP.RXRA	TFP.GATA2	TFP.CCNT2	TFP.BATF	TFP.TAL1	TFP.POU2F2	MCV-85	NA	chr22,40350001,40360000,chr2,96710001,96720000,246,Hi-C	chr22,40350001,40360000,chr4,190700001,190710000,5,Hi-C	NA	LM9,3.4226
22	40362946	rs138006	NM_004810,GRAP2	ENST00000344138,ENSG00000100351	ENST00000478445,ENSG00000100351	ENST00000407075,ENSG00000100351	ENST00000481263,ENSG00000100351	TFP.JUND	CHMM	TFP.CEBPB	TFP.EP300	TFP.TBP	TFP.STAT3	TFP.GATA1	MCV-2	NA	chr22,40360001,40370000,chr19,14300001,14310000,30,Hi-C	chr22,40360001,40370000,chr22,39010001,39020000,5,Hi-C	chr22,40360001,40370000,chr22,42970001,42980000,12,Hi-C	NA	MEF-2,1.3035	PR,1.2838	PR,1.2639	SRF,16.2319	NA	NA	NA	NA	NA	NA	0.000	0.268	0.814	E/GM	G	NA	NA
22	40363778	rs2284078	NM_004810,GRAP2	ENST00000344138,ENSG00000100351	ENST00000407075,ENSG00000100351	ENST00000481263,ENSG00000100351	CHMM	TFP.CEBPB	TFP.TBP	TFP.GATA1	TFP.TFAP2C	TFP.TFAP2A	TFP.EP300	TFP.GATA2	TFP.CCNT2	TFP.TAL1	NA	chr22,40360001,40370000,chr19,14300001,14310000,30,Hi-C	chr22,40360001,40370000,chr22,39010001,39020000,5,Hi-C	chr22,40360001,40370000,chr22,42970001,42980000,12,Hi-C	NA	Nkx2-9_3082,1.8884	Obox1_3970,1.3041	Obox6_3440,2.3031	Rsc30-primary,1.3003	Rsc30-primary,2.1369	NA	NA	NA	NA	NA	NA	0.000	-0.591	-2.68	GM0	A

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:0)
(Waiting for update.)

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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