PedAM

Pediatric Disease Annotations & Medicines


	gastroparesis

Disease ID	833
Disease	gastroparesis
Definition	Chronic delayed gastric emptying. Gastroparesis may be caused by motor dysfunction or paralysis of STOMACH muscles or may be associated with other systemic diseases such as DIABETES MELLITUS.
Synonym	atony stomach delayed gastric emptying gastric atonia gastric atonia (disorder) gastric atony gastric paralysis gastric stases gastric stasis gastroparalysis gastropareses gastroparesis (disorder) gastroparesis [disease/finding] gastroparesis syndrome gastroparesis syndrome (disorder) gastroparesis syndrome (disorder) [ambiguous] gastroparesis syndrome, nos paralysis gastric stases, gastric stasis, gastric stomach atony
DOID	DOID:11914
ICD10	ICD10CM:K31.84
UMLS	C0152020
MeSH	D018589
SNOMED-CT	SNOMEDCT_US_2016_09_01:196753007;SNOMEDCT_US_2016_09_01:235675006
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:22) C0011847 \| diabetes \| 17 C0011849 \| diabetes mellitus \| 7 C0003467 \| anxiety \| 2 C0011860 \| type 2 diabetes \| 2 C0023890 \| cirrhosis \| 2 C0023890 \| liver cirrhosis \| 2 C0011854 \| type 1 diabetes \| 2 C0011854 \| type 1 diabetes mellitus \| 2 C0030567 \| parkinson's disease \| 2 C0001173 \| gastric outlet obstruction \| 1 C0442874 \| neuropathy \| 1 C0011880 \| diabetic ketoacidosis \| 1 C0751651 \| mitochondrial disorder \| 1 C0001418 \| adenocarcinoma \| 1 C0162429 \| poor nutrition \| 1 C0009319 \| colitis \| 1 C0011570 \| depression \| 1 C0038353 \| gastric dilatation \| 1 C0017178 \| gastrointestinal disorders \| 1 C0017178 \| gastrointestinal disorder \| 1 C0035309 \| retinopathy \| 1 C0259749 \| autonomic neuropathy \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:1) HMOX1 \| 3162 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:10) 5243 \| ABCB1 \| infer 148 \| ADRA1A \| infer 147 \| ADRA1B \| infer 146 \| ADRA1D \| infer 1565 \| CYP2D6 \| infer 1813 \| DRD2 \| infer 3753 \| KCNE1 \| infer 9992 \| KCNE2 \| infer 3757 \| KCNH2 \| infer 3784 \| KCNQ1 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:95) 10573 \| MRPL28 \| DISEASES 28954 \| REM1 \| DISEASES 9552 \| SPAG7 \| DISEASES 3162 \| HMOX1 \| DISEASES 479 \| ATP12A \| DISEASES 2862 \| MLNR \| DISEASES 5216 \| PFN1 \| DISEASES 5539 \| PPY \| DISEASES 4254 \| KITLG \| DISEASES 2729 \| GCLC \| DISEASES 5754 \| PTK7 \| DISEASES 8574 \| AKR7A2 \| DISEASES 4360 \| MRC1 \| DISEASES 2693 \| GHSR \| DISEASES 8189 \| SYMPK \| DISEASES 7166 \| TPH1 \| DISEASES 3630 \| INS \| DISEASES 384 \| ARG2 \| DISEASES 3757 \| KCNH2 \| DISEASES 495 \| ATP4A \| DISEASES 25939 \| SAMHD1 \| DISEASES 126374 \| WTIP \| DISEASES 3782 \| KCNN3 \| DISEASES 90226 \| UCN2 \| DISEASES 2746 \| GLUD1 \| DISEASES 6327 \| SCN2B \| DISEASES 7345 \| UCHL1 \| DISEASES 6750 \| SST \| DISEASES 3815 \| KIT \| DISEASES 9992 \| KCNE2 \| DISEASES 6285 \| S100B \| DISEASES 114757 \| CYGB \| DISEASES 4880 \| NPPC \| DISEASES 886 \| CCKAR \| DISEASES 213 \| ALB \| DISEASES 94274 \| PPP1R14A \| DISEASES 2353 \| FOS \| DISEASES 147 \| ADRA1B \| DISEASES 3352 \| HTR1D \| DISEASES 619373 \| MBOAT4 \| DISEASES 3350 \| HTR1A \| DISEASES 147912 \| SIX5 \| DISEASES 8630 \| HSD17B6 \| DISEASES 6863 \| TAC1 \| DISEASES 64840 \| PORCN \| DISEASES 7485 \| WRB \| DISEASES 8905 \| AP1S2 \| DISEASES 4105 \| MAGEA6 \| DISEASES 8519 \| IFITM1 \| DISEASES 2520 \| GAST \| DISEASES 3751 \| KCND2 \| DISEASES 51738 \| GHRL \| DISEASES 885 \| CCK \| DISEASES 1103 \| CHAT \| DISEASES 4842 \| NOS1 \| DISEASES 3363 \| HTR7 \| DISEASES 54468 \| MIOS \| DISEASES 80320 \| SP6 \| DISEASES 4882 \| NPR2 \| DISEASES 259307 \| IL4I1 \| DISEASES 55107 \| ANO1 \| DISEASES 3359 \| HTR3A \| DISEASES 6525 \| SMTN \| DISEASES 5697 \| PYY \| DISEASES 3360 \| HTR4 \| DISEASES 1813 \| DRD2 \| DISEASES 28514 \| DLL1 \| DISEASES 7432 \| VIP \| DISEASES 4881 \| NPR1 \| DISEASES 2730 \| GCLM \| DISEASES 23413 \| NCS1 \| DISEASES 51230 \| PHF20 \| DISEASES 1041 \| CDSN \| DISEASES 1804 \| DPP6 \| DISEASES 146 \| ADRA1D \| DISEASES 114131 \| UCN3 \| DISEASES 7054 \| TH \| DISEASES 1814 \| DRD3 \| DISEASES 9290 \| GPR55 \| DISEASES 100131390 \| SP9 \| DISEASES 594857 \| NPS \| DISEASES 643418 \| LIPN \| DISEASES 2115 \| ETV1 \| DISEASES 2641 \| GCG \| DISEASES 4295 \| MLN \| DISEASES 5817 \| PVR \| DISEASES 221833 \| SP8 \| DISEASES 51227 \| PIGP \| DISEASES 149466 \| C1orf210 \| DISEASES 56 \| ACRV1 \| DISEASES 5125 \| PCSK5 \| DISEASES 102723508 \| KANTR \| DISEASES 103752588 \| PACERR \| DISEASES 692149 \| SCARNA14 \| DISEASES 100128252 \| ZNF667-AS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	833
Disease	gastroparesis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:16) HP:0002018 \| Nausea \| 9 HP:0002013 \| Emesis \| 8 HP:0002017 \| Nausea and vomiting \| 7 HP:0000819 \| Diabetes mellitus \| 7 HP:0002578 \| Gastroparesis \| 5 HP:0002835 \| Aspiration \| 2 HP:0001394 \| Hepatic cirrhosis \| 2 HP:0000739 \| Anxiety \| 2 HP:0012531 \| Pain \| 1 HP:0001993 \| Ketoacidosis \| 1 HP:0012378 \| Fatigue \| 1 HP:0000488 \| Noninflammatory retina disease \| 1 HP:0001953 \| Diabetic ketosis \| 1 HP:0000716 \| Depression \| 1 HP:0001944 \| Dehydration \| 1 HP:0002583 \| Colitis \| 1

Disease ID	833
Disease	gastroparesis
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:7) C0027497 \| nausea \| 9 C0042963 \| vomiting \| 8 C0011849 \| diabetes mellitus \| 7 C0003467 \| anxiety \| 2 C0750323 \| intractable vomiting \| 1 C0011570 \| depression \| 1 C0030193 \| pain \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:2)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0152020	cisapride	D020117	81098-60-4	gastroparesis	MESH:D018589	therapeutic	11578711
C0152020	vincristine	D014750	-	gastroparesis	MESH:D018589	marker/mechanism	19448908

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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