PedAM
Pediatric Disease Annotations & Medicines
| gastrinoma | ||||
| Disease ID | 1466 |
|---|---|
| Disease | gastrinoma |
| Definition | A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1). |
| Synonym | [m]gastrinoma nos [m]gastrinoma nos (morphologic abnormality) g cell tumor g cell tumor, nos g cell tumour g-cell gastrin producing tumor g-cell tumor gastrin cell tumor gastrin cell tumour gastrin producing tumor gastrin secreting tumor gastrin-producing net gastrin-producing neuroendocrine tumor gastrin-producing tumor gastrin-producing tumors gastrinoma (disorder) gastrinoma (morphologic abnormality) gastrinoma [disease/finding] gastrinoma, nos gastrinomas islet cell tumor, ulcerogenic tumor, gastrin-producing tumors, gastrin-producing ulcerogenic islet cell tumor |
| DOID | |
| UMLS | C0017150 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:18) C0025267 | multiple endocrine neoplasia type 1 | 2 C0494165 | liver metastases | 2 C0043515 | zollinger-ellison syndrome | 2 C0494165 | liver metastasis | 2 C0027662 | multiple endocrine neoplasia | 2 C0494165 | hepatic metastases | 1 C1333321 | duodenal gastrinoma | 1 C0030920 | peptic ulcer disease | 1 C0021670 | insulinomas | 1 C0030920 | peptic ulcer | 1 C0013295 | duodenal ulcer | 1 C0013295 | duodenal ulcers | 1 C0085113 | neurofibromatosis | 1 C0392525 | nephrolithiasis | 1 C0038358 | gastric ulceration | 1 C0038358 | gastric ulcer | 1 C0206754 | neuroendocrine tumor | 1 C0206754 | neuroendocrine tumors | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:1) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:41) 6344 | SCTR | DISEASES 5837 | PYGM | DISEASES 6343 | SCT | DISEASES 1113 | CHGA | DISEASES 479 | ATP12A | DISEASES 5539 | PPY | DISEASES 2026 | ENO2 | DISEASES 583 | BBS2 | DISEASES 2864 | FFAR1 | DISEASES 3630 | INS | DISEASES 3727 | JUND | DISEASES 4922 | NTS | DISEASES 2922 | GRP | DISEASES 4829 | NMBR | DISEASES 495 | ATP4A | DISEASES 8455 | ATRN | DISEASES 6855 | SYP | DISEASES 5443 | POMC | DISEASES 9616 | RNF7 | DISEASES 5741 | PTH | DISEASES 6750 | SST | DISEASES 6755 | SSTR5 | DISEASES 6746 | SSR2 | DISEASES 5617 | PRL | DISEASES 5066 | PAM | DISEASES 56776 | FMN2 | DISEASES 2520 | GAST | DISEASES 796 | CALCA | DISEASES 885 | CCK | DISEASES 4221 | MEN1 | DISEASES 6752 | SSTR2 | DISEASES 259230 | SGMS1 | DISEASES 7432 | VIP | DISEASES 2740 | GLP1R | DISEASES 5089 | PBX2 | DISEASES 3274 | HRH2 | DISEASES 1114 | CHGB | DISEASES 4828 | NMB | DISEASES 6345 | SRL | DISEASES 2641 | GCG | DISEASES 4295 | MLN | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1466 |
|---|---|
| Disease | gastrinoma |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:9) HP:0002664 | Neoplasia | 4 HP:0100568 | Endocrine neoplasia | 3 HP:0002044 | Zollinger-Ellison syndrome | 2 HP:0000787 | Renal calculi | 1 HP:0002588 | Duodenal ulcer | 1 HP:0004398 | Peptic ulcer | 1 HP:0001289 | Confusion | 1 HP:0001067 | Neurofibromas | 1 HP:0002592 | Stomach ulcer | 1 |
| Disease ID | 1466 |
|---|---|
| Disease | gastrinoma |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:4) C0043515 | zollinger-ellison syndrome | 2 C0494165 | liver metastasis | 2 C0494165 | liver metastases | 2 C0494165 | hepatic metastases | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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GWASdb Annotation(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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Mapped by lexical matching(Total Items:0) |
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Mapped by homologous gene(Total Items:0) |
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Chemical(Total Drugs:0) | |
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FDA approved drug and dosage information(Total Drugs:0) | |
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FDA labeling changes(Total Drugs:0) | |
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