PedAM

Pediatric Disease Annotations & Medicines


	ganglioneuroma

Disease ID	1467
Disease	ganglioneuroma
Definition	A benign neoplasm that usually arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. The tumor may present clinically with HORNER SYNDROME or diarrhea due to ectopic production of vasoactive intestinal peptide. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p966)
Synonym	gangliocytoma gangliocytoma (morphologic abnormality) gangliocytomas ganglioneurofibroma ganglioneuroma (disorder) ganglioneuroma (morphologic abnormality) ganglioneuroma (schwannian stroma-dominant) ganglioneuroma [disease/finding] ganglioneuroma [dup] (morphologic abnormality) ganglioneuroma, benign ganglioneuromas neural crest tumor, benign
Orphanet	ORPHANET:251992 ORPHANET:251937
DOID	DOID:4817 DOID:2426
UMLS	C0017075
MeSH	D005729
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:18) C0032000 \| pituitary adenoma \| 5 C0001430 \| adenoma \| 4 C0031511 \| pheochromocytoma \| 4 C0085113 \| neurofibromatosis \| 4 C0030421 \| paraganglioma \| 2 C0206654 \| leiomyomatosis \| 1 C0041408 \| turner syndrome \| 1 C0205698 \| undifferentiated carcinoma \| 1 C0032460 \| polycystic ovarian disease \| 1 C0001418 \| adenocarcinoma \| 1 C0032000 \| pituitary adenomas \| 1 C0023798 \| lipomas \| 1 C0023798 \| lipoma \| 1 C0494165 \| hepatic metastasis \| 1 C0221406 \| cushing's disease \| 1 C0346302 \| gh-secreting pituitary adenoma \| 1 C0751690 \| malignant peripheral nerve sheath tumor \| 1 C0001206 \| acromegaly \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:122) 4804 \| NGFR \| DISEASES 5816 \| PVALB \| DISEASES 1113 \| CHGA \| DISEASES 1113 \| CHGA \| DISEASES 5173 \| PDYN \| DISEASES 5173 \| PDYN \| DISEASES 79152 \| FA2H \| DISEASES 657 \| BMPR1A \| DISEASES 5539 \| PPY \| DISEASES 2735 \| GLI1 \| DISEASES 2026 \| ENO2 \| DISEASES 2026 \| ENO2 \| DISEASES 1611 \| DAP \| DISEASES 2691 \| GHRH \| DISEASES 4852 \| NPY \| DISEASES 5266 \| PI3 \| DISEASES 8484 \| GALR3 \| DISEASES 10389 \| SCML2 \| DISEASES 25796 \| PGLS \| DISEASES 9253 \| NUMBL \| DISEASES 9104 \| RGN \| DISEASES 2670 \| GFAP \| DISEASES 4922 \| NTS \| DISEASES 759 \| CA1 \| DISEASES 10752 \| CHL1 \| DISEASES 2799 \| GNS \| DISEASES 11019 \| LIAS \| DISEASES 2769 \| GNA15 \| DISEASES 6855 \| SYP \| DISEASES 6855 \| SYP \| DISEASES 790 \| CAD \| DISEASES 5443 \| POMC \| DISEASES 5443 \| POMC \| DISEASES 6389 \| SDHA \| DISEASES 793 \| CALB1 \| DISEASES 51083 \| GAL \| DISEASES 50846 \| DHH \| DISEASES 3073 \| HEXA \| DISEASES 7157 \| TP53 \| DISEASES 7157 \| TP53 \| DISEASES 5409 \| PNMT \| DISEASES 805 \| CALM2 \| DISEASES 9180 \| OSMR \| DISEASES 8795 \| TNFRSF10B \| DISEASES 1392 \| CRH \| DISEASES 4915 \| NTRK2 \| DISEASES 4613 \| MYCN \| DISEASES 6750 \| SST \| DISEASES 6750 \| SST \| DISEASES 808 \| CALM3 \| DISEASES 6271 \| S100A1 \| DISEASES 6271 \| S100A1 \| DISEASES 7805 \| LAPTM5 \| DISEASES 64320 \| RNF25 \| DISEASES 6853 \| SYN1 \| DISEASES 26266 \| SLC13A4 \| DISEASES 717 \| C2 \| DISEASES 322 \| APBB1 \| DISEASES 2587 \| GALR1 \| DISEASES 11318 \| GPR182 \| DISEASES 8772 \| FADD \| DISEASES 5617 \| PRL \| DISEASES 5604 \| MAP2K1 \| DISEASES 7857 \| SCG2 \| DISEASES 5066 \| PAM \| DISEASES 794 \| CALB2 \| DISEASES 1540 \| CYLD \| DISEASES 947 \| CD34 \| DISEASES 23262 \| PPIP5K2 \| DISEASES 27122 \| DKK3 \| DISEASES 4684 \| NCAM1 \| DISEASES 6863 \| TAC1 \| DISEASES 8811 \| GALR2 \| DISEASES 10215 \| OLIG2 \| DISEASES 2520 \| GAST \| DISEASES 9402 \| GRAP2 \| DISEASES 4771 \| NF2 \| DISEASES 26762 \| HAVCR1 \| DISEASES 5979 \| RET \| DISEASES 5789 \| PTPRD \| DISEASES 5725 \| PTBP1 \| DISEASES 801 \| CALM1 \| DISEASES 85569 \| GALP \| DISEASES 6752 \| SSTR2 \| DISEASES 4763 \| NF1 \| DISEASES 841 \| CASP8 \| DISEASES 2526 \| FUT4 \| DISEASES 4886 \| NPY1R \| DISEASES 4535 \| MT-ND1 \| DISEASES 7432 \| VIP \| DISEASES 6391 \| SDHC \| DISEASES 2173 \| FABP7 \| DISEASES 4288 \| MKI67 \| DISEASES 4803 \| NGF \| DISEASES 9118 \| INA \| DISEASES 51684 \| SUFU \| DISEASES 5728 \| PTEN \| DISEASES 5728 \| PTEN \| DISEASES 5081 \| PAX7 \| DISEASES 6390 \| SDHB \| DISEASES 6392 \| SDHD \| DISEASES 171023 \| ASXL1 \| DISEASES 8434 \| RECK \| DISEASES 54880 \| BCOR \| DISEASES 7054 \| TH \| DISEASES 1621 \| DBH \| DISEASES 7021 \| TFAP2B \| DISEASES 23164 \| MPRIP \| DISEASES 116372 \| LYPD1 \| DISEASES 594857 \| NPS \| DISEASES 344022 \| NOTO \| DISEASES 6295 \| SAG \| DISEASES 146713 \| RBFOX3 \| DISEASES 146713 \| RBFOX3 \| DISEASES 116 \| ADCYAP1 \| DISEASES 3831 \| KLC1 \| DISEASES 6513 \| SLC2A1 \| DISEASES 7033 \| TFF3 \| DISEASES 4914 \| NTRK1 \| DISEASES 10381 \| TUBB3 \| DISEASES 10381 \| TUBB3 \| DISEASES 100507588 \| TGFBR3L \| DISEASES
Locus	(Waiting for update.)

Disease ID	1467
Disease	ganglioneuroma
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:16) HP:0002574 \| Episodic abdominal pain HP:0002239 \| Gastrointestinal hemorrhage HP:0003005 \| Ganglioneuroma HP:0004390 \| Hamartomatous polyposis HP:0100631 \| Neoplasm of the adrenal gland HP:0002034 \| Abnormality of the rectum HP:0003330 \| Abnormal bone structure HP:0005220 \| Multiple intestinal neurofibromatosis HP:0000822 \| Hypertension HP:0200063 \| Colorectal polyposis HP:0007110 \| Central hypoventilation HP:0045026 \| Abnormality of the mediastinum HP:0008775 \| Abnormality of the prostate HP:0000315 \| Abnormality of the orbital region HP:0005249 \| Functional intestinal obstruction HP:0000834 \| Abnormality of the adrenal glands
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:10) HP:0002664 \| Neoplasia \| 5 HP:0002893 \| Pituitary adenoma \| 5 HP:0002666 \| Pheochromocytoma \| 4 HP:0001067 \| Neurofibromas \| 4 HP:0002668 \| Paragangliomas \| 2 HP:0100697 \| Neurofibrosarcoma \| 1 HP:0001250 \| Seizures \| 1 HP:0007332 \| Hemifacial seizures \| 1 HP:0000845 \| Acromegalic growth \| 1 HP:0012032 \| Lipoma \| 1

Disease ID	1467
Disease	ganglioneuroma
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0001206 \| acromegaly \| 1 C1608408 \| malignant transformation \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:0)
(Waiting for update.)

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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