PedAM

Pediatric Disease Annotations & Medicines


	ganglioneuroblastoma

Disease ID	954
Disease	ganglioneuroblastoma
Definition	A moderately malignant neoplasm composed of primitive neuroectodermal cells dispersed in myxomatous or fibrous stroma intermixed with mature ganglion cells. It may undergo transformation into a neuroblastoma. It arises from the sympathetic trunk or less frequently from the adrenal medulla, cerebral cortex, and other locations. Cervical ganglioneuroblastomas may be associated with HORNER SYNDROME and the tumor may occasionally secrete vasoactive intestinal peptide, resulting in chronic diarrhea.
Synonym	ganglioneuroblastoma (disorder) ganglioneuroblastoma (morphologic abnormality) ganglioneuroblastoma [disease/finding] ganglioneuroblastoma, malignant ganglioneuroblastomas
Orphanet	ORPHANET:251877
DOID	DOID:4163
UMLS	C0206718
MeSH	D018305
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:4) C0014038 \| encephalitis \| 1 C0031511 \| pheochromocytoma \| 1 C0553580 \| ewing's sarcoma \| 1 C0027819 \| neuroblastoma \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:66) 51052 \| PRLH \| DISEASES 54474 \| KRT20 \| DISEASES 4804 \| NGFR \| DISEASES 6820 \| SULT2B1 \| DISEASES 1113 \| CHGA \| DISEASES 5949 \| RBP3 \| DISEASES 8929 \| PHOX2B \| DISEASES 3732 \| CD82 \| DISEASES 2597 \| GAPDH \| DISEASES 2026 \| ENO2 \| DISEASES 1611 \| DAP \| DISEASES 3398 \| ID2 \| DISEASES 2023 \| ENO1 \| DISEASES 4852 \| NPY \| DISEASES 10389 \| SCML2 \| DISEASES 9253 \| NUMBL \| DISEASES 4922 \| NTS \| DISEASES 2799 \| GNS \| DISEASES 6855 \| SYP \| DISEASES 5443 \| POMC \| DISEASES 2052 \| EPHX1 \| DISEASES 4915 \| NTRK2 \| DISEASES 4613 \| MYCN \| DISEASES 55294 \| FBXW7 \| DISEASES 6750 \| SST \| DISEASES 8566 \| PDXK \| DISEASES 643 \| CXCR5 \| DISEASES 57572 \| DOCK6 \| DISEASES 64320 \| RNF25 \| DISEASES 717 \| C2 \| DISEASES 10296 \| MAEA \| DISEASES 5598 \| MAPK7 \| DISEASES 3350 \| HTR1A \| DISEASES 10611 \| PDLIM5 \| DISEASES 2253 \| FGF8 \| DISEASES 2027 \| ENO3 \| DISEASES 7490 \| WT1 \| DISEASES 10810 \| WASF3 \| DISEASES 3266 \| ERAS \| DISEASES 9260 \| PDLIM7 \| DISEASES 5789 \| PTPRD \| DISEASES 85569 \| GALP \| DISEASES 4763 \| NF1 \| DISEASES 23560 \| GTPBP4 \| DISEASES 7432 \| VIP \| DISEASES 7391 \| USF1 \| DISEASES 2173 \| FABP7 \| DISEASES 5654 \| HTRA1 \| DISEASES 965 \| CD58 \| DISEASES 4803 \| NGF \| DISEASES 51684 \| SUFU \| DISEASES 1491 \| CTH \| DISEASES 27063 \| ANKRD1 \| DISEASES 4609 \| MYC \| DISEASES 57126 \| CD177 \| DISEASES 7054 \| TH \| DISEASES 238 \| ALK \| DISEASES 344022 \| NOTO \| DISEASES 23028 \| KDM1A \| DISEASES 3112 \| HLA-DOB \| DISEASES 10163 \| WASF2 \| DISEASES 2130 \| EWSR1 \| DISEASES 116 \| ADCYAP1 \| DISEASES 4914 \| NTRK1 \| DISEASES 10381 \| TUBB3 \| DISEASES 100507588 \| TGFBR3L \| DISEASES
Locus	(Waiting for update.)

Disease ID	954
Disease	ganglioneuroblastoma
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:6) HP:0002666 \| Pheochromocytoma \| 1 HP:0003006 \| Neuroblastoma \| 1 HP:0002383 \| Encephalitis \| 1 HP:0001336 \| Myoclonic jerks \| 1 HP:0012254 \| Ewing's sarcoma \| 1 HP:0010543 \| Opsoclonus \| 1

Disease ID	954
Disease	ganglioneuroblastoma
Manually Symptom	UMLS \| Name(Total Manually Symptoms:6) C1963091 \| diarrhea C0745186 \| hypoventilation syndrome C0700208 \| scoliosis C0030472 \| paraneoplastic syndromes C0030472 \| paraneoplastic syndrome C0010481 \| cushing's syndrome
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0206718	phenytoin	D010672	57-41-0	ganglioneuroblastoma	MESH:D018305	marker/mechanism	6106127

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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