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PedAM

Pediatric Disease Annotations & Medicines



   fibrolamellar carcinoma
  

Disease ID 1446
Disease fibrolamellar carcinoma
Definition
A distinctive type of liver cell carcinoma that arises in non-cirrhotic livers and is seen predominantly in young patients. The tumor cells are polygonal and deeply eosinophilic, and are embedded in a fibrous stroma. The prognosis is similar to classical hepatocellular carcinoma that arises in non-cirrhotic livers, and better than hepatocellular carcinoma that arises in cirrhotic livers.
Synonym
[m] hepatocellular carcinoma, fibrolamellar
[m]hepatocellular carcinoma, fibrolamellar
fibrolamellar carcinoma of liver cells
fibrolamellar carcinoma of the liver cells
fibrolamellar hepatocellular carcinoma
fibrolamellar hepatocellular carcinoma (disorder)
fibrolamellar variant of hepatocellular carcinoma
flc
hepatocellular carcinoma (fibrolamellar variant)
hepatocellular carcinoma, fibrolamellar
hepatocellular carcinoma, fibrolamellar (morphologic abnormality)
hepatocellular fibrolamellar carcinoma
liver cell fibrolamellar carcinoma
oncocytic hepatocellular tumor
polygonal cell type hepatocellular carcinoma with fibrous stroma
Orphanet
DOID
UMLS
C0334287
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:1)
C0162510  |  caroli's syndrome  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:2)
DNAJB1  |  3337  |  ORPHANET
PRKACA  |  5566  |  ORPHANET
Inferring Gene(Waiting for update.)
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:39)
5009  |  OTC  |  DISEASES
6790  |  AURKA  |  DISEASES
7249  |  TSC2  |  DISEASES
4953  |  ODC1  |  DISEASES
1846  |  DUSP4  |  DISEASES
968  |  CD68  |  DISEASES
8431  |  NR0B2  |  DISEASES
3337  |  DNAJB1  |  DISEASES
4922  |  NTS  |  DISEASES
6947  |  TCN1  |  DISEASES
6521  |  SLC4A1  |  DISEASES
6502  |  SKP2  |  DISEASES
90737  |  PAGE5  |  DISEASES
10642  |  IGF2BP1  |  DISEASES
5122  |  PCSK1  |  DISEASES
81037  |  CLPTM1L  |  DISEASES
153562  |  MARVELD2  |  DISEASES
3855  |  KRT7  |  DISEASES
5133  |  PDCD1  |  DISEASES
9075  |  CLDN2  |  DISEASES
5329  |  PLAUR  |  DISEASES
1364  |  CLDN4  |  DISEASES
92737  |  DNER  |  DISEASES
5265  |  SERPINA1  |  DISEASES
11186  |  RASSF1  |  DISEASES
6597  |  SMARCA4  |  DISEASES
2475  |  MTOR  |  DISEASES
3880  |  KRT19  |  DISEASES
383  |  ARG1  |  DISEASES
169792  |  GLIS3  |  DISEASES
3083  |  HGFAC  |  DISEASES
2719  |  GPC3  |  DISEASES
174  |  AFP  |  DISEASES
7122  |  CLDN5  |  DISEASES
10551  |  AGR2  |  DISEASES
5578  |  PRKCA  |  DISEASES
23089  |  PEG10  |  DISEASES
6256  |  RXRA  |  DISEASES
220107  |  DLEU7  |  DISEASES
Locus(Waiting for update.)
Disease ID 1446
Disease fibrolamellar carcinoma
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype(Waiting for update.)
Disease ID 1446
Disease fibrolamellar carcinoma
Manually Symptom(Waiting for update.)
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:0)
(Waiting for update.)
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)