Home Contact Sitemap

PedAM

Pediatric Disease Annotations & Medicines



   fetal hydantoin syndrome
  

Disease ID 873
Disease fetal hydantoin syndrome
Definition
A teratogenic disorder observed in a newborn or child of a mother who was exposed to phenytoin during pregnancy. Manifestations include dysmorphic craniofacial features, hypoplastic distal phalanges and nails, growth delay and delayed psychomotor development.(NICHD)
Synonym
dilantin embryopathy
dilantin syndrome
fetal dilantin syndrome
fetal hydantoin syndrome (disorder)
fetal phenytoin syndrome
fetal phenytoin syndrome (disorder)
foetal hydantoin syndrome
hydantoin syndrome
meadow's syndrome
phenytoin embryopathy
Orphanet
ICD10
UMLS
C0265372
SNOMED-CT
Curated Gene(Waiting for update.)
Inferring Gene(Waiting for update.)
Text Mined Gene(Waiting for update.)
Locus(Waiting for update.)
Disease ID 873
Disease fetal hydantoin syndrome
Integrated Phenotype
HPO | Name(Total Integrated Phenotypes:30)
HP:0002208  |  Coarse hair
HP:0000364  |  Hearing abnormality
HP:0001804  |  Hypoplastic fingernail
HP:0007477  |  Abnormal dermatoglyphics
HP:0001263  |  Global developmental delay
HP:0000286  |  Epicanthus
HP:0001199  |  Triphalangeal thumb
HP:0004322  |  Short stature
HP:0000235  |  Abnormality of the fontanelles or cranial sutures
HP:0003196  |  Short nose
HP:0000474  |  Thickened nuchal skin fold
HP:0000486  |  Strabismus
HP:0001626  |  Abnormality of the cardiovascular system
HP:0000508  |  Ptosis
HP:0000377  |  Abnormality of the pinna
HP:0002162  |  Low posterior hairline
HP:0002664  |  Neoplasm
HP:0000154  |  Wide mouth
HP:0000316  |  Hypertelorism
HP:0009882  |  Short distal phalanx of finger
HP:0000028  |  Cryptorchidism
HP:0000368  |  Low-set, posteriorly rotated ears
HP:0001511  |  Intrauterine growth retardation
HP:0000457  |  Depressed nasal ridge
HP:0000048  |  Bifid scrotum
HP:0100790  |  Hernia
HP:0000252  |  Microcephaly
HP:0000175  |  Cleft palate
HP:0000232  |  Everted lower lip vermilion
HP:0006610  |  Wide intermamillary distance
Text Mined Phenotype(Waiting for update.)
Disease ID 873
Disease fetal hydantoin syndrome
Manually Symptom
UMLS  | Name(Total Manually Symptoms:3)
C1305909  |  truncus arteriosus
C0262585  |  onychopathy
C0020598  |  hypocalcemia
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:1)
HP ID HP Name MP ID MP Name Annotation
HP:0001660Truncus arteriosusMP:0011662persistent truncus arteriosus type ii;
Mapped by homologous gene(Total Items:1)
HP ID HP Name MP ID MP Name Annotation
HP:0002901HypocalcemiaMP:0010465aberrant origin of the right subclavian artery;HP:0001660Truncus arteriosus
Chemical(Total Drugs:1)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0265372phenytoinD01067257-41-0fetal hydantoin syndromeMESH:C537922marker/mechanism25726414
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)