fetal hydantoin syndrome |
Disease ID | 873 |
---|---|
Disease | fetal hydantoin syndrome |
Definition | A teratogenic disorder observed in a newborn or child of a mother who was exposed to phenytoin during pregnancy. Manifestations include dysmorphic craniofacial features, hypoplastic distal phalanges and nails, growth delay and delayed psychomotor development.(NICHD) |
Synonym | dilantin embryopathy dilantin syndrome fetal dilantin syndrome fetal hydantoin syndrome (disorder) fetal phenytoin syndrome fetal phenytoin syndrome (disorder) foetal hydantoin syndrome hydantoin syndrome meadow's syndrome phenytoin embryopathy |
Orphanet | |
ICD10 | |
UMLS | C0265372 |
SNOMED-CT | |
Curated Gene | (Waiting for update.) |
Inferring Gene | (Waiting for update.) |
Text Mined Gene | (Waiting for update.) |
Locus | (Waiting for update.) |
Disease ID | 873 |
---|---|
Disease | fetal hydantoin syndrome |
Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:30) HP:0002208 | Coarse hair HP:0000364 | Hearing abnormality HP:0001804 | Hypoplastic fingernail HP:0007477 | Abnormal dermatoglyphics HP:0001263 | Global developmental delay HP:0000286 | Epicanthus HP:0001199 | Triphalangeal thumb HP:0004322 | Short stature HP:0000235 | Abnormality of the fontanelles or cranial sutures HP:0003196 | Short nose HP:0000474 | Thickened nuchal skin fold HP:0000486 | Strabismus HP:0001626 | Abnormality of the cardiovascular system HP:0000508 | Ptosis HP:0000377 | Abnormality of the pinna HP:0002162 | Low posterior hairline HP:0002664 | Neoplasm HP:0000154 | Wide mouth HP:0000316 | Hypertelorism HP:0009882 | Short distal phalanx of finger HP:0000028 | Cryptorchidism HP:0000368 | Low-set, posteriorly rotated ears HP:0001511 | Intrauterine growth retardation HP:0000457 | Depressed nasal ridge HP:0000048 | Bifid scrotum HP:0100790 | Hernia HP:0000252 | Microcephaly HP:0000175 | Cleft palate HP:0000232 | Everted lower lip vermilion HP:0006610 | Wide intermamillary distance |
Text Mined Phenotype | (Waiting for update.) |
Disease ID | 873 |
---|---|
Disease | fetal hydantoin syndrome |
Manually Symptom | UMLS | Name(Total Manually Symptoms:3) |
Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
---|
(Waiting for update.) |
All Snps(Total Genotypes:0) | |
---|---|
(Waiting for update.) |
GWASdb Annotation(Total Genotypes:0) | |
---|---|
(Waiting for update.) |
GWASdb Snp Trait(Total Genotypes:0) | |
---|---|
(Waiting for update.) |
Mapped by lexical matching(Total Items:1) | ||||
---|---|---|---|---|
HP ID | HP Name | MP ID | MP Name | Annotation |
HP:0001660 | Truncus arteriosus | MP:0011662 | persistent truncus arteriosus type ii; |
Mapped by homologous gene(Total Items:1) | ||||
---|---|---|---|---|
HP ID | HP Name | MP ID | MP Name | Annotation |
HP:0002901 | Hypocalcemia | MP:0010465 | aberrant origin of the right subclavian artery;HP:0001660 | Truncus arteriosus |
Chemical(Total Drugs:1) | |||||||||
---|---|---|---|---|---|---|---|---|---|
CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
C0265372 | phenytoin | D010672 | 57-41-0 | fetal hydantoin syndrome | MESH:C537922 | marker/mechanism | 25726414 |
FDA approved drug and dosage information(Total Drugs:0) | |
---|---|
(Waiting for update.) |
FDA labeling changes(Total Drugs:0) | |
---|---|
(Waiting for update.) |