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Pediatric Disease Annotations & Medicines



   exotropia
  

Disease ID 1557
Disease exotropia
Definition
A form of ocular misalignment where the visual axes diverge inappropriately. For example, medial rectus muscle weakness may produce this condition as the affected eye will deviate laterally upon attempted forward gaze. An exotropia occurs due to the relatively unopposed force exerted on the eye by the lateral rectus muscle, which pulls the eye in an outward direction.
Synonym
divergent concomitant strabismus
divergent concomitant strabismus (disorder)
divergent squint
divergent strabismus
exodeviation
exodeviations
exotropia (disorder)
exotropia [disease/finding]
exotropia nos
exotropia nos (disorder)
exotropia, nos
exotropia, unspecified
external strabismus
outward facing eye ball
strabismus, divergent
unspecified exotropia
unspecified exotropia (disorder)
xt - exotropia
DOID
ICD10
UMLS
C0015310
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:24)
C0038379  |  strabismus  |  8
C0152134  |  internuclear ophthalmoplegia  |  2
C0020575  |  hypertropia  |  2
C0005745  |  ptosis  |  2
C0002418  |  amblyopia  |  2
C0014877  |  esotropia  |  2
C0014306  |  enophthalmos  |  1
C0014544  |  epilepsy  |  1
C0013261  |  duane's retraction syndrome  |  1
C0155336  |  accommodative esotropia  |  1
C0003081  |  anisometropia  |  1
C0456909  |  vision loss  |  1
C0024796  |  marfan syndrome  |  1
C0010273  |  crouzon syndrome  |  1
C0007789  |  cerebral palsy  |  1
C0028866  |  oculomotor nerve palsy  |  1
C0029089  |  ophthalmoplegia  |  1
C0086543  |  cataracts  |  1
C0015300  |  proptosis  |  1
C0028866  |  third nerve palsy  |  1
C0004106  |  astigmatism  |  1
C0750903  |  strabismic amblyopia  |  1
C0011570  |  depression  |  1
C0022578  |  keratoconus  |  1
Curated Gene(Waiting for update.)
Inferring Gene(Waiting for update.)
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:83)
6820  |  SULT2B1  |  DISEASES
1947  |  EFNB1  |  DISEASES
1652  |  DDT  |  DISEASES
57167  |  SALL4  |  DISEASES
54623  |  PAF1  |  DISEASES
3191  |  HNRNPL  |  DISEASES
8929  |  PHOX2B  |  DISEASES
2069  |  EREG  |  DISEASES
80896  |  NPL  |  DISEASES
6386  |  SDCBP  |  DISEASES
6496  |  SIX3  |  DISEASES
8482  |  SEMA7A  |  DISEASES
25939  |  SAMHD1  |  DISEASES
10133  |  OPTN  |  DISEASES
4036  |  LRP2  |  DISEASES
374  |  AREG  |  DISEASES
10923  |  SUB1  |  DISEASES
4715  |  NDUFB9  |  DISEASES
701  |  BUB1B  |  DISEASES
54069  |  MIS18A  |  DISEASES
1409  |  CRYAA  |  DISEASES
84343  |  HPS3  |  DISEASES
401  |  PHOX2A  |  DISEASES
90167  |  FRMD7  |  DISEASES
322  |  APBB1  |  DISEASES
9427  |  ECEL1  |  DISEASES
27166  |  PRELID1  |  DISEASES
5308  |  PITX2  |  DISEASES
80025  |  PANK2  |  DISEASES
258  |  AMBN  |  DISEASES
6773  |  STAT2  |  DISEASES
64388  |  GREM2  |  DISEASES
2193  |  FARSA  |  DISEASES
11145  |  PLA2G16  |  DISEASES
2253  |  FGF8  |  DISEASES
2200  |  FBN1  |  DISEASES
2303  |  FOXC2  |  DISEASES
56478  |  EIF4ENIF1  |  DISEASES
6900  |  CNTN2  |  DISEASES
8398  |  PLA2G6  |  DISEASES
668  |  FOXL2  |  DISEASES
55589  |  BMP2K  |  DISEASES
5493  |  PPL  |  DISEASES
401138  |  AMTN  |  DISEASES
2066  |  ERBB4  |  DISEASES
1760  |  DMPK  |  DISEASES
1798  |  DPAGT1  |  DISEASES
54716  |  SLC6A20  |  DISEASES
1785  |  DNM2  |  DISEASES
157680  |  VPS13B  |  DISEASES
23607  |  CD2AP  |  DISEASES
11169  |  WDHD1  |  DISEASES
55605  |  KIF21A  |  DISEASES
3211  |  HOXB1  |  DISEASES
6905  |  TBCE  |  DISEASES
3664  |  IRF6  |  DISEASES
7827  |  NPHS2  |  DISEASES
1805  |  DPT  |  DISEASES
57216  |  VANGL2  |  DISEASES
4534  |  MTM1  |  DISEASES
9124  |  PDLIM1  |  DISEASES
1907  |  EDN2  |  DISEASES
2739  |  GLO1  |  DISEASES
7546  |  ZIC2  |  DISEASES
169522  |  KCNV2  |  DISEASES
9467  |  SH3BP5  |  DISEASES
51651  |  PTRH2  |  DISEASES
4287  |  ATXN3  |  DISEASES
685  |  BTC  |  DISEASES
10117  |  ENAM  |  DISEASES
64221  |  ROBO3  |  DISEASES
643418  |  LIPN  |  DISEASES
1123  |  CHN1  |  DISEASES
348180  |  CTU2  |  DISEASES
55636  |  CHD7  |  DISEASES
23210  |  JMJD6  |  DISEASES
57506  |  MAVS  |  DISEASES
7086  |  TKT  |  DISEASES
89782  |  LMLN  |  DISEASES
2533  |  FYB  |  DISEASES
100463289  |  MTRNR2L5  |  DISEASES
10381  |  TUBB3  |  DISEASES
4566  |  MT-TK  |  DISEASES
Locus(Waiting for update.)
Disease ID 1557
Disease exotropia
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:28)
HP:0000486  |  Squint eyes  |  9
HP:0000619  |  Convergence insufficiency  |  3
HP:0030773  |  Internuclear ophthalmoplegia  |  2
HP:0010877  |  Unilateral strabismus  |  2
HP:0000565  |  Inward turning of one or both eyes  |  2
HP:0000646  |  Wandering eyes  |  2
HP:0000508  |  Drooping upper eyelid  |  2
HP:0000572  |  Visual loss  |  2
HP:0001260  |  Dysarthric speech  |  1
HP:0012803  |  Anisometropia  |  1
HP:0009917  |  Persistent pupillary membrane  |  1
HP:0000563  |  Conical cornea  |  1
HP:0000520  |  Anterior bulging of the globe of eye  |  1
HP:0100021  |  Cerebral palsy  |  1
HP:0000518  |  Cataract  |  1
HP:0002664  |  Neoplasia  |  1
HP:0000613  |  Extreme light sensitivity  |  1
HP:0000716  |  Depression  |  1
HP:0000602  |  Ophthalmoplegia  |  1
HP:0007011  |  Superior oblique palsy  |  1
HP:0012246  |  Oculomotor nerve palsy  |  1
HP:0012531  |  Pain  |  1
HP:0000490  |  Sunken eyes  |  1
HP:0000483  |  Astigmatism  |  1
HP:0002273  |  Tetraparesis  |  1
HP:0004439  |  Crouzon syndrome  |  1
HP:0009916  |  Asymmetric pupil sizes  |  1
HP:0100022  |  Movement disorder  |  1
Disease ID 1557
Disease exotropia
Manually Symptom(Waiting for update.)
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:1)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0015310lorazepamD008140846-49-1exotropiaMESH:D005099marker/mechanism16586087
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)