PedAM

Pediatric Disease Annotations & Medicines


	exanthem

Disease ID	664
Disease	exanthem
Definition	Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.
Synonym	[d]exanthem [d]exanthem (context-dependent category) [d]exanthem (situation) [d]rash and other nonspecific skin eruption [d]rash and other nonspecific skin eruption (context-dependent category) [d]rash and other nonspecific skin eruption (situation) [d]rash and other nonspecific skin eruption nos [d]rash and other nonspecific skin eruption nos (context-dependent category) [d]rash and other nonspecific skin eruption nos (situation) [d]spots breaking out - eruption cutaneous eruption cutaneous eruption (morphologic abnormality) cutaneous eruption on skin cutaneous eruption, nos cutaneous eruptions efflorescence eruption eruption (disorder) eruption of skin eruption of skin (disorder) eruption, nos exanthema exanthema [disease/finding] exanthemas exanthemata exanthems nonspecif skin erupt nec rash rash and other nonspecific skin eruption rash, nos rash, skin rashes skin eruption skin rash skin rashes spots spots [d]
DOID	DOID:0050486
ICD10	ICD10CM:R21
UMLS	C0015230
MeSH	D005076
SNOMED-CT	SNOMEDCT_US_2016_09_01:271807003
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:6) C0022660 \| acute renal failure \| 1 C0042769 \| viral infections \| 1 C0026393 \| molluscum contagiosum \| 1 C0032285 \| pneumoniae \| 1 C0042769 \| viral infection \| 1 C0035078 \| renal failure \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:3) MVK \| 4598 \| CTD_human HLA-B \| 3106 \| CTD_human C1QA \| 712 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:353) 5898 \| RALA \| DISEASES 920 \| CD4 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 6128 \| RPL6 \| DISEASES 22798 \| LAMB4 \| DISEASES 350 \| APOH \| DISEASES 2099 \| ESR1 \| DISEASES 201294 \| UNC13D \| DISEASES 5711 \| PSMD5 \| DISEASES 2940 \| GSTA3 \| DISEASES 3002 \| GZMB \| DISEASES 6790 \| AURKA \| DISEASES 10857 \| PGRMC1 \| DISEASES 64743 \| WDR13 \| DISEASES 479 \| ATP12A \| DISEASES 123876 \| ACSM2A \| DISEASES 6361 \| CCL17 \| DISEASES 79650 \| USB1 \| DISEASES 4210 \| MEFV \| DISEASES 2137 \| EXTL3 \| DISEASES 7038 \| TG \| DISEASES 8797 \| TNFRSF10A \| DISEASES 166 \| AES \| DISEASES 973 \| CD79A \| DISEASES 4818 \| NKG7 \| DISEASES 1048 \| CEACAM5 \| DISEASES 1577 \| CYP3A5 \| DISEASES 4353 \| MPO \| DISEASES 1440 \| CSF3 \| DISEASES 9487 \| PIGL \| DISEASES 6347 \| CCL2 \| DISEASES 3558 \| IL2 \| DISEASES 4598 \| MVK \| DISEASES 3458 \| IFNG \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 374291 \| NDUFS7 \| DISEASES 5657 \| PRTN3 \| DISEASES 6402 \| SELL \| DISEASES 4317 \| MMP8 \| DISEASES 9429 \| ABCG2 \| DISEASES 8997 \| KALRN \| DISEASES 2322 \| FLT3 \| DISEASES 80352 \| RNF39 \| DISEASES 2069 \| EREG \| DISEASES 718 \| C3 \| DISEASES 1773 \| DNASE1 \| DISEASES 5199 \| CFP \| DISEASES 29108 \| PYCARD \| DISEASES 968 \| CD68 \| DISEASES 3630 \| INS \| DISEASES 5894 \| RAF1 \| DISEASES 4695 \| NDUFA2 \| DISEASES 6155 \| RPL27 \| DISEASES 6737 \| TRIM21 \| DISEASES 1401 \| CRP \| DISEASES 3845 \| KRAS \| DISEASES 5156 \| PDGFRA \| DISEASES 269 \| AMHR2 \| DISEASES 3569 \| IL6 \| DISEASES 3557 \| IL1RN \| DISEASES 26525 \| IL36RN \| DISEASES 10850 \| CCL27 \| DISEASES 2766 \| GMPR \| DISEASES 1588 \| CYP19A1 \| DISEASES 6496 \| SIX3 \| DISEASES 1559 \| CYP2C9 \| DISEASES 6741 \| SSB \| DISEASES 9360 \| PPIG \| DISEASES 4069 \| LYZ \| DISEASES 23483 \| TGDS \| DISEASES 1800 \| DPEP1 \| DISEASES 5159 \| PDGFRB \| DISEASES 2324 \| FLT4 \| DISEASES 9172 \| MYOM2 \| DISEASES 945 \| CD33 \| DISEASES 6521 \| SLC4A1 \| DISEASES 51816 \| CECR1 \| DISEASES 495 \| ATP4A \| DISEASES 23523 \| CABIN1 \| DISEASES 3553 \| IL1B \| DISEASES 64135 \| IFIH1 \| DISEASES 10578 \| GNLY \| DISEASES 3791 \| KDR \| DISEASES 943 \| TNFRSF8 \| DISEASES 5317 \| PKP1 \| DISEASES 5290 \| PIK3CA \| DISEASES 1001 \| CDH3 \| DISEASES 2817 \| GPC1 \| DISEASES 1615 \| DARS \| DISEASES 8808 \| IL1RL2 \| DISEASES 59067 \| IL21 \| DISEASES 6774 \| STAT3 \| DISEASES 80725 \| SRCIN1 \| DISEASES 3383 \| ICAM1 \| DISEASES 3827 \| KNG1 \| DISEASES 1950 \| EGF \| DISEASES 22797 \| TFEC \| DISEASES 5243 \| ABCB1 \| DISEASES 5286 \| PIK3C2A \| DISEASES 121260 \| SLC15A4 \| DISEASES 2065 \| ERBB3 \| DISEASES 2252 \| FGF7 \| DISEASES 3480 \| IGF1R \| DISEASES 7157 \| TP53 \| DISEASES 2064 \| ERBB2 \| DISEASES 207 \| AKT1 \| DISEASES 2212 \| FCGR2A \| DISEASES 5972 \| REN \| DISEASES 285362 \| SUMF1 \| DISEASES 55435 \| AP1AR \| DISEASES 9180 \| OSMR \| DISEASES 167410 \| LIX1 \| DISEASES 1956 \| EGFR \| DISEASES 3439 \| IFNA1 \| DISEASES 710 \| SERPING1 \| DISEASES 2206 \| MS4A2 \| DISEASES 7108 \| TM7SF2 \| DISEASES 3606 \| IL18 \| DISEASES 5805 \| PTS \| DISEASES 54842 \| MFSD6 \| DISEASES 2321 \| FLT1 \| DISEASES 10 \| NAT2 \| DISEASES 10563 \| CXCL13 \| DISEASES 163786 \| SASS6 \| DISEASES 6750 \| SST \| DISEASES 3815 \| KIT \| DISEASES 1636 \| ACE \| DISEASES 114757 \| CYGB \| DISEASES 6352 \| CCL5 \| DISEASES 2215 \| FCGR3B \| DISEASES 213 \| ALB \| DISEASES 4724 \| NDUFS4 \| DISEASES 3562 \| IL3 \| DISEASES 1437 \| CSF2 \| DISEASES 5896 \| RAG1 \| DISEASES 201161 \| CENPV \| DISEASES 5347 \| PLK1 \| DISEASES 64127 \| NOD2 \| DISEASES 55957 \| LIN37 \| DISEASES 54442 \| KCTD5 \| DISEASES 80150 \| ASRGL1 \| DISEASES 6356 \| CCL11 \| DISEASES 5604 \| MAP2K1 \| DISEASES 414301 \| DDI1 \| DISEASES 116984 \| ARAP2 \| DISEASES 143501 \| C11orf40 \| DISEASES 83987 \| CCDC8 \| DISEASES 6036 \| RNASE2 \| DISEASES 51181 \| DCXR \| DISEASES 1493 \| CTLA4 \| DISEASES 171558 \| PTCRA \| DISEASES 54658 \| UGT1A1 \| DISEASES 8625 \| RFXANK \| DISEASES 340024 \| SLC6A19 \| DISEASES 118429 \| ANTXR2 \| DISEASES 6504 \| SLAMF1 \| DISEASES 686 \| BTD \| DISEASES 56246 \| MRAP \| DISEASES 9451 \| EIF2AK3 \| DISEASES 126669 \| SHE \| DISEASES 2147 \| F2 \| DISEASES 8534 \| CHST1 \| DISEASES 3265 \| HRAS \| DISEASES 6868 \| ADAM17 \| DISEASES 23536 \| ADAT1 \| DISEASES 947 \| CD34 \| DISEASES 26470 \| SEZ6L2 \| DISEASES 4179 \| CD46 \| DISEASES 354 \| KLK3 \| DISEASES 1776 \| DNASE1L3 \| DISEASES 1775 \| DNASE1L2 \| DISEASES 10044 \| SH2D3C \| DISEASES 10318 \| TNIP1 \| DISEASES 4684 \| NCAM1 \| DISEASES 64388 \| GREM2 \| DISEASES 91662 \| NLRP12 \| DISEASES 158056 \| MAMDC4 \| DISEASES 10938 \| EHD1 \| DISEASES 149830 \| PRNT \| DISEASES 1351 \| COX8A \| DISEASES 9920 \| KBTBD11 \| DISEASES 2274 \| FHL2 \| DISEASES 199699 \| DAND5 \| DISEASES 56984 \| PSMG2 \| DISEASES 5663 \| PSEN1 \| DISEASES 716 \| C1S \| DISEASES 29933 \| GPR132 \| DISEASES 338324 \| S100A7A \| DISEASES 8971 \| H1FX \| DISEASES 6401 \| SELE \| DISEASES 796 \| CALCA \| DISEASES 338321 \| NLRP9 \| DISEASES 140691 \| TRIM69 \| DISEASES 113179 \| ADAT3 \| DISEASES 340075 \| ARSI \| DISEASES 150372 \| NFAM1 \| DISEASES 117194 \| MRGPRX2 \| DISEASES 3043 \| HBB \| DISEASES 2152 \| F3 \| DISEASES 5133 \| PDCD1 \| DISEASES 1665 \| DHX15 \| DISEASES 81608 \| FIP1L1 \| DISEASES 114548 \| NLRP3 \| DISEASES 51477 \| ISYNA1 \| DISEASES 1576 \| CYP3A4 \| DISEASES 3141 \| HLCS \| DISEASES 23583 \| SMUG1 \| DISEASES 123228 \| SENP8 \| DISEASES 5781 \| PTPN11 \| DISEASES 374393 \| FAM111B \| DISEASES 5064 \| PALM \| DISEASES 2066 \| ERBB4 \| DISEASES 921 \| CD5 \| DISEASES 3605 \| IL17A \| DISEASES 54716 \| SLC6A20 \| DISEASES 4948 \| OCA2 \| DISEASES 7267 \| TTC3 \| DISEASES 5979 \| RET \| DISEASES 51155 \| HN1 \| DISEASES 64067 \| NPAS3 \| DISEASES 6288 \| SAA1 \| DISEASES 5169 \| ENPP3 \| DISEASES 7867 \| MAPKAPK3 \| DISEASES 6714 \| SRC \| DISEASES 51592 \| TRIM33 \| DISEASES 2526 \| FUT4 \| DISEASES 6364 \| CCL20 \| DISEASES 57162 \| PELI1 \| DISEASES 5336 \| PLCG2 \| DISEASES 6693 \| SPN \| DISEASES 1565 \| CYP2D6 \| DISEASES 54106 \| TLR9 \| DISEASES 58484 \| NLRC4 \| DISEASES 7150 \| TOP1 \| DISEASES 2475 \| MTOR \| DISEASES 9760 \| TOX \| DISEASES 4283 \| CXCL9 \| DISEASES 7052 \| TGM2 \| DISEASES 28514 \| DLL1 \| DISEASES 5743 \| PTGS2 \| DISEASES 8676 \| STX11 \| DISEASES 3459 \| IFNGR1 \| DISEASES 1805 \| DPT \| DISEASES 7371 \| UCK2 \| DISEASES 2214 \| FCGR3A \| DISEASES 912 \| CD1D \| DISEASES 6278 \| S100A7 \| DISEASES 6283 \| S100A12 \| DISEASES 54855 \| FAM46C \| DISEASES 914 \| CD2 \| DISEASES 4893 \| NRAS \| DISEASES 8517 \| IKBKG \| DISEASES 7272 \| TTK \| DISEASES 1806 \| DPYD \| DISEASES 2334 \| AFF2 \| DISEASES 959 \| CD40LG \| DISEASES 93377 \| OPALIN \| DISEASES 1558 \| CYP2C8 \| DISEASES 1557 \| CYP2C19 \| DISEASES 5728 \| PTEN \| DISEASES 7422 \| VEGFA \| DISEASES 25 \| ABL1 \| DISEASES 9338 \| TCEAL1 \| DISEASES 100 \| ADA \| DISEASES 54657 \| UGT1A4 \| DISEASES 2833 \| CXCR3 \| DISEASES 253430 \| IPMK \| DISEASES 1043 \| CD52 \| DISEASES 7780 \| SLC30A2 \| DISEASES 3339 \| HSPG2 \| DISEASES 5696 \| PSMB8 \| DISEASES 55920 \| RCC2 \| DISEASES 3376 \| IARS \| DISEASES 3055 \| HCK \| DISEASES 50943 \| FOXP3 \| DISEASES 3107 \| HLA-C \| DISEASES 7133 \| TNFRSF1B \| DISEASES 1041 \| CDSN \| DISEASES 9576 \| SPAG6 \| DISEASES 3105 \| HLA-A \| DISEASES 5394 \| EXOSC10 \| DISEASES 3274 \| HRH2 \| DISEASES 765 \| CA6 \| DISEASES 8718 \| TNFRSF25 \| DISEASES 64421 \| DCLRE1C \| DISEASES 768 \| CA9 \| DISEASES 3980 \| LIG3 \| DISEASES 9445 \| ITM2B \| DISEASES 8559 \| PRPF18 \| DISEASES 2683 \| B4GALT1 \| DISEASES 3301 \| DNAJA1 \| DISEASES 54790 \| TET2 \| DISEASES 7010 \| TEK \| DISEASES 3704 \| ITPA \| DISEASES 3440 \| IFNA2 \| DISEASES 3456 \| IFNB1 \| DISEASES 29126 \| CD274 \| DISEASES 79954 \| NOL10 \| DISEASES 10457 \| GPNMB \| DISEASES 6736 \| SRY \| DISEASES 28227 \| PPP2R3B \| DISEASES 26091 \| HERC4 \| DISEASES 54535 \| CCHCR1 \| DISEASES 5609 \| MAP2K7 \| DISEASES 161357 \| MDGA2 \| DISEASES 23515 \| MORC3 \| DISEASES 728441 \| GGT2 \| DISEASES 9048 \| ARTN \| DISEASES 2641 \| GCG \| DISEASES 4295 \| MLN \| DISEASES 414918 \| DENND6B \| DISEASES 100144748 \| KLLN \| DISEASES 57801 \| HES4 \| DISEASES 197 \| AHSG \| DISEASES 720 \| C4A \| DISEASES 7124 \| TNF \| DISEASES 3106 \| HLA-B \| DISEASES 159371 \| SLC35G1 \| DISEASES 7072 \| TIA1 \| DISEASES 6490 \| PMEL \| DISEASES 9278 \| ZBTB22 \| DISEASES 84148 \| KAT8 \| DISEASES 81704 \| DOCK8 \| DISEASES 204801 \| NLRP11 \| DISEASES 834 \| CASP1 \| DISEASES 3586 \| IL10 \| DISEASES 51686 \| OAZ3 \| DISEASES 3712 \| IVD \| DISEASES 79012 \| CAMKV \| DISEASES 30816 \| ERVW-1 \| DISEASES 4345 \| CD200 \| DISEASES 131870 \| NUDT16 \| DISEASES 51428 \| DDX41 \| DISEASES 727897 \| MUC5B \| DISEASES 930 \| CD19 \| DISEASES 567 \| B2M \| DISEASES 7732 \| RNF112 \| DISEASES 51741 \| WWOX \| DISEASES 820 \| CAMP \| DISEASES 6625 \| SNRNP70 \| DISEASES 102723508 \| KANTR \| DISEASES 103752588 \| PACERR \| DISEASES 677777 \| SCARNA12 \| DISEASES 677767 \| SCARNA7 \| DISEASES 654321 \| SNORA75 \| DISEASES 9301 \| SNORD27 \| DISEASES 9298 \| SNORD31 \| DISEASES 26802 \| SNORD47 \| DISEASES 26770 \| SNORD79 \| DISEASES 692225 \| SNORD94 \| DISEASES 102659353 \| THRIL \| DISEASES 100128252 \| ZNF667-AS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	664
Disease	exanthem
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:6) HP:0002373 \| Febrile convulsions \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0001945 \| Fever \| 1 HP:0001250 \| Seizures \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0040189 \| Desquamation \| 1

Disease ID	664
Disease	exanthem
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:3) C0009450 \| infection \| 1 C0032285 \| pneumoniae \| 1 C0042769 \| viral infections \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:56)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs104894833	22305854	2717	GLA	umls:C0015230	BeFree	Recently, male subjects harboring the c.196G>C nucleotide change which leads to the E66Q enzyme having low α-galactosidase A (GLA) activity have been identified at an unexpectedly high frequency on Japanese and Korean screening for Fabry disease involving dry blood spots and plasma/serum samples.	0.002171535	2012	GLA;RPL36A-HNRNPH2	X	101403984	C	G
rs121912438	15501831	6647	SOD1	umls:C0015230	BeFree	Nine and 36 protein spots displayed elevated and suppressed abundance respectively in G93A-SOD1-expressing cells.	0.000814326	2004	SOD1	21	31667299	G	C
rs121918456	12161596	5781	PTPN11	umls:C0015230	BeFree	We hypothesise that some PTPN11 mutations are associated with the typical Noonan syndrome phenotype and that other mutations, such as the Y279C mutation reported here, are associated with both the Noonan syndrome phenotype and with skin pigmentation anomalies, such as multiple lentigines or café au lait spots.	0.001085767	2002	PTPN11	12	112473023	A	C,G
rs1799782	14716779	27306	HPGDS	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000814326	2004	XRCC1	19	43553422	G	A
rs1799782	14716779	4552	MTRR	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43553422	G	A
rs1799782	14716779	1728	NQO1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43553422	G	A
rs1799782	14716779	4353	MPO	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43553422	G	A
rs1799782	14716779	7515	XRCC1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43553422	G	A
rs1799782	14716779	2944	GSTM1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.001357209	2004	XRCC1	19	43553422	G	A
rs1799782	14716779	2952	GSTT1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000542884	2004	XRCC1	19	43553422	G	A
rs1801394	14716779	2944	GSTM1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.001357209	2004	MTRR;FASTKD3	5	7870860	A	G
rs1801394	14716779	7515	XRCC1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	MTRR;FASTKD3	5	7870860	A	G
rs1801394	14716779	4552	MTRR	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	MTRR;FASTKD3	5	7870860	A	G
rs1801394	14716779	2952	GSTT1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000542884	2004	MTRR;FASTKD3	5	7870860	A	G
rs1801394	14716779	1728	NQO1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	MTRR;FASTKD3	5	7870860	A	G
rs1801394	14716779	4353	MPO	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	MTRR;FASTKD3	5	7870860	A	G
rs1801394	14716779	27306	HPGDS	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000814326	2004	MTRR;FASTKD3	5	7870860	A	G
rs1893592	25843625	53347	UBASH3A	umls:C0015230	BeFree	A statistically significant association was observed between UBASH3A rs1893592 C allele and skin rash, oral ulcer and arthritis (p<0.05).	0.000271442	2015	UBASH3A	21	42434957	A	C
rs25487	14716779	2952	GSTT1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000542884	2004	XRCC1	19	43551574	T	C
rs25487	14716779	4552	MTRR	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43551574	T	C
rs25487	14716779	2944	GSTM1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.001357209	2004	XRCC1	19	43551574	T	C
rs25487	14716779	4353	MPO	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43551574	T	C
rs25487	14716779	7515	XRCC1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43551574	T	C
rs25487	14716779	27306	HPGDS	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000814326	2004	XRCC1	19	43551574	T	C
rs25487	14716779	1728	NQO1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43551574	T	C
rs25489	14716779	4552	MTRR	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43552260	C	T,G
rs25489	14716779	27306	HPGDS	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000814326	2004	XRCC1	19	43552260	C	T,G
rs25489	14716779	2952	GSTT1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000542884	2004	XRCC1	19	43552260	C	T,G
rs25489	14716779	2944	GSTM1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.001357209	2004	XRCC1	19	43552260	C	T,G
rs25489	14716779	7515	XRCC1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43552260	C	T,G
rs25489	14716779	1728	NQO1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43552260	C	T,G
rs25489	14716779	4353	MPO	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	XRCC1	19	43552260	C	T,G
rs267606990	19449407	5781	PTPN11	umls:C0015230	BeFree	The patient was found to carry a de novo PTPN11 mutation p.T2I as well as the maternally inherited NF1 mutation c.4661+1G>C. Her otherwise healthy mother and brother, who also had the NF1 mutation, showed few café-au-lait spots as the only sign of neurofibromatosis.	0.001085767	2009	PTPN11;RPL6	12	112419116	C	T
rs376919235	14716779	1728	NQO1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	MPO	17	58279366	A	G
rs376919235	14716779	4353	MPO	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	MPO	17	58279366	A	G
rs376919235	14716779	2952	GSTT1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000542884	2004	MPO	17	58279366	A	G
rs376919235	14716779	7515	XRCC1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	MPO	17	58279366	A	G
rs376919235	14716779	2944	GSTM1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.001357209	2004	MPO	17	58279366	A	G
rs376919235	14716779	27306	HPGDS	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000814326	2004	MPO	17	58279366	A	G
rs376919235	14716779	4552	MTRR	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	MPO	17	58279366	A	G
rs386493716	14716779	2952	GSTT1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000542884	2004	NA	NA	NA	NA	NA
rs386493716	14716779	27306	HPGDS	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000814326	2004	NA	NA	NA	NA	NA
rs386493716	14716779	1728	NQO1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	NA	NA	NA	NA	NA
rs386493716	14716779	7515	XRCC1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	NA	NA	NA	NA	NA
rs386493716	14716779	2944	GSTM1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.001357209	2004	NA	NA	NA	NA	NA
rs386493716	14716779	4552	MTRR	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	NA	NA	NA	NA	NA
rs386493716	14716779	4353	MPO	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	NA	NA	NA	NA	NA
rs386545546	14716779	2952	GSTT1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000542884	2004	NA	NA	NA	NA	NA
rs386545546	14716779	2944	GSTM1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.001357209	2004	NA	NA	NA	NA	NA
rs386545546	14716779	1728	NQO1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	NA	NA	NA	NA	NA
rs386545546	14716779	4353	MPO	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	NA	NA	NA	NA	NA
rs386545546	14716779	4552	MTRR	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	NA	NA	NA	NA	NA
rs386545546	14716779	27306	HPGDS	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000814326	2004	NA	NA	NA	NA	NA
rs386545546	14716779	7515	XRCC1	umls:C0015230	BeFree	Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), myeloperoxidase (MPO) (C(-)463T), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1) (C609T), 5,10-methylenetetrahydrofolate reductase (MTHFR) (C677T), MTHFR (A1298C), methionine synthase reductase (MTRR) (A66G), X-ray repair cross complementing 1 (XRCC1) 194 (Arg194Trp), XRCC1 280 (Arg280His), and XRCC1 399 (Arg399Gln) alleles was performed by TaqMan analysis using DNA isolated from newborn heel-stick spots provided by the Minnesota Department of Health.	0.000271442	2004	NA	NA	NA	NA	NA
rs397507531	19120036	5781	PTPN11	umls:C0015230	BeFree	We suggest that the atypical severe symptoms in the index patient may be caused by an additive effect on the F285L mutation in PTPN11 by another mutation, for example the NF1 R1809C or alternatively, the not yet identified gene mutation associated with CAL spots in this family.	0.001085767	2009	PTPN11	12	112473040	T	C,G
rs397516810	19120036	5781	PTPN11	umls:C0015230	BeFree	We suggest that the atypical severe symptoms in the index patient may be caused by an additive effect on the F285L mutation in PTPN11 by another mutation, for example the NF1 R1809C or alternatively, the not yet identified gene mutation associated with CAL spots in this family.	0.001085767	2009	PTPN11	12	112477652	T	G

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:18)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
2	60534199	rs6545803	G	T	rs6545803	21810746	6.00E-06	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	rs6545803-G	Research Support, Non-U.S. Gov't	G	NA	NA
5	89780971	rs2562519	C	T	rs2562519	21810746	5.00E-06	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	rs2562519-A	Research Support, Non-U.S. Gov't	G	POLR3G	intron
6	29913298	rs1061235	A	T	rs1061235	21428769	1.00E-07	NA	9.12	[4.03-20.65]	65 European ancestry cases; 3,987 European ancestry controls	European(4052)	ALL(4052)	EUR(4052)	ALL(4052)	Adverse response to carbamapezine	HPOID:0000988	Skin rash	DOID:37	DOID:0060056	skin disease	hypersensitivity reaction disease	D002220	Carbamazepine	response to anticonvulsant	Skin disease	Immunologic deficiency syndrome	NA	Research Support, N.I.H., Extramural
6	31109810	rs1265087	G	A	rs1265087	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	C	CCHCR1	nearGene-3
6	31109946	rs2523834	T	A	rs2523834	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	A	CCHCR1	nearGene-3
6	31109947	rs2523833	C	T	rs2523833	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	G	CCHCR1	nearGene-3
6	31110391	rs1576	G	C	rs1576	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	C	CCHCR1	missense
6	31112108	rs1265079	G	T	rs1265079	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	C	CCHCR1	intron
6	31112602	rs1265078	G	C	rs1265078	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	C	CCHCR1	intron
6	31113083	rs1265076	G	A	rs1265076	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	C	CCHCR1	intron
6	31113940	rs746646	T	C	rs746646	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	A	CCHCR1	intron
6	31114182	rs746647	A	G	rs746647	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	T	CCHCR1	intron
6	31115700	rs1265069	A	G	rs1265069	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	T	CCHCR1	intron
6	31116142	rs1265067	G	A	rs1265067	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	C	CCHCR1	intron
6	31117188	rs1265114	C	T	rs1265114	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	G	CCHCR1	intron
6	31118019	rs1265112	T	C	rs1265112	21810746	1.00E-08	NA	4.36	[2.58-7.36]	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	rs1265112-G	Research Support, Non-U.S. Gov't	A	CCHCR1	intron
6	31118942	rs2517985	T	C	rs2517985	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	A	CCHCR1	intron
6	31119380	rs1265111	G	A	rs1265111	21810746	1.21E-08	NA	NA	NA	72 Thai nevirapine-induced rash patients; 77 Thai nevirapine-tolerant rash patients	Thai(149)	ALL(149)	ASN(149)	ALL(149)	Nevirapine-induced rash	HPOID:0000988	Skin rash	DOID:0050486	exanthem	NA	NA	response to reverse transcriptase inhibitor	Skin disease	NA	Research Support, Non-U.S. Gov't	C,T	CCHCR1	intron

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:80)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0015230	acetaminophen	D000082	103-90-2	exanthema	MESH:D005076	marker/mechanism	18377375
C0015230	allopurinol	D000493	315-30-0	exanthema	MESH:D005076	marker/mechanism	11450872
C0015230	amcinonide	C012716	-	exanthema	MESH:D005076	marker/mechanism	10894975
C0015230	amifostine	D004999	20537-88-6	exanthema	MESH:D005076	marker/mechanism	10688811
C0015230	aminoglutethimide	D000616	125-84-8	exanthema	MESH:D005076	marker/mechanism	6123383
C0015230	amlodipine	D017311	88150-42-9	exanthema	MESH:D005076	marker/mechanism	10940749
C0015230	ampicillin	D000667	69-53-4	exanthema	MESH:D005076	marker/mechanism	4025903
C0015230	arsenic trioxide	C006632	1327-53-3	exanthema	MESH:D005076	marker/mechanism	9801394
C0015230	atenolol	D001262	29122-68-7	exanthema	MESH:D005076	marker/mechanism	1378155
C0015230	azithromycin	D017963	83905-01-5	exanthema	MESH:D005076	marker/mechanism	11247598
C0015230	aztreonam	D001398	78110-38-0	exanthema	MESH:D005076	marker/mechanism	2967033
C0015230	carbamazepine	D002220	298-46-4	exanthema	MESH:D005076	marker/mechanism	12005248
C0015230	carbimazole	D002231	22232-54-8	exanthema	MESH:D005076	marker/mechanism	15785249
C0015230	cefdinir	C056814	-	exanthema	MESH:D005076	marker/mechanism	18377375
C0015230	celecoxib	D000068579	-	exanthema	MESH:D005076	marker/mechanism	11390425
C0015230	chlorambucil	D002699	305-03-3	exanthema	MESH:D005076	marker/mechanism	19122478
C0015230	chloramphenicol	D002701	56-75-7	exanthema	MESH:D005076	marker/mechanism	4800729
C0015230	chlorpromazine	D002746	50-53-3	exanthema	MESH:D005076	marker/mechanism	4247303
C0015230	cimetidine	D002927	51481-61-9	exanthema	MESH:D005076	marker/mechanism	375397
C0015230	ciprofloxacin	D002939	85721-33-1	exanthema	MESH:D005076	marker/mechanism	10688811
C0015230	clonidine	D003000	4205-90-7	exanthema	MESH:D005076	marker/mechanism	3836300
C0015230	clozapine	D003024	5786-21-0	exanthema	MESH:D005076	marker/mechanism	15671137
C0015230	codeine	D003061	76-57-3	exanthema	MESH:D005076	marker/mechanism	4025903
C0015230	cyclophosphamide	D003520	50-18-0	exanthema	MESH:D005076	marker/mechanism	1677714
C0015230	cyclosporine	D016572	59865-13-3	exanthema	MESH:D005076	therapeutic	16114793
C0015230	dapsone	D003622	80-08-0	exanthema	MESH:D005076	marker/mechanism	10812824
C0015230	deferasirox	C415250	-	exanthema	MESH:D005076	marker/mechanism	17233848
C0015230	diatrizoate	D003973	117-96-4	exanthema	MESH:D005076	marker/mechanism	3972525
C0015230	cisplatin	D002945	15663-27-1	exanthema	MESH:D005076	marker/mechanism	21778302
C0015230	diclofenac	D004008	15307-86-5	exanthema	MESH:D005076	marker/mechanism	2033230
C0015230	dicloxacillin	D004009	3116-76-5	exanthema	MESH:D005076	marker/mechanism	8742666
C0015230	diltiazem	D004110	42399-41-7	exanthema	MESH:D005076	marker/mechanism	2699494
C0015230	doxycycline	D004318	564-25-0	exanthema	MESH:D005076	marker/mechanism	6268571
C0015230	enalapril	D004656	75847-73-3	exanthema	MESH:D005076	marker/mechanism	2541310
C0015230	ethambutol	D004977	74-55-5	exanthema	MESH:D005076	marker/mechanism	18583892
C0015230	everolimus	D000068338	-	exanthema	MESH:D005076	marker/mechanism	21306238
C0015230	fluconazole	D015725	86386-73-4	exanthema	MESH:D005076	therapeutic	10466905
C0015230	fluvoxamine	D016666	54739-18-3	exanthema	MESH:D005076	marker/mechanism	17644482
C0015230	leucovorin	D002955	1958/5/9	exanthema	MESH:D005076	therapeutic	6607976
C0015230	gemcitabine	C056507	103882-84-4	exanthema	MESH:D005076	marker/mechanism	10955861
C0015230	glutathione	D005978	70-18-8	exanthema	MESH:D005076	marker/mechanism	8377599
C0015230	imatinib mesylate	D000068877	-	exanthema	MESH:D005076	marker/mechanism	11549802
C0015230	imipramine	D007099	50-49-7	exanthema	MESH:D005076	marker/mechanism	4610613
C0015230	indomethacin	D007213	53-86-1	exanthema	MESH:D005076	marker/mechanism	16943303
C0015230	labetalol	D007741	36894-69-6	exanthema	MESH:D005076	marker/mechanism	2873208
C0015230	lamotrigine	C047781	84057-84-1	exanthema	MESH:D005076	marker/mechanism	10448828
C0015230	linezolid	D000069349	-	exanthema	MESH:D005076	marker/mechanism	19733945
C0015230	loracarbef	C054920	-	exanthema	MESH:D005076	marker/mechanism	1621750
C0015230	lovastatin	D008148	75330-75-5	exanthema	MESH:D005076	marker/mechanism	3055921
C0015230	medroxyprogesterone acetate	D017258	71-58-9	exanthema	MESH:D005076	marker/mechanism	6123383
C0015230	mephenytoin	D008617	1950/12/4	exanthema	MESH:D005076	marker/mechanism	1001284
C0015230	mesna	D015080	19767-45-4	exanthema	MESH:D005076	marker/mechanism	16333822
C0015230	methotrexate	D008727	1959/5/2	exanthema	MESH:D005076	marker/mechanism	1450620
C0015230	metoprolol	D008790	37350-58-6	exanthema	MESH:D005076	marker/mechanism	12090909
C0015230	morphine	D009020	57-27-2	exanthema	MESH:D005076	marker/mechanism	6111570
C0015230	nafcillin	D009254	147-52-4	exanthema	MESH:D005076	marker/mechanism	7467307
C0015230	nelfinavir	D019888	159989-64-7	exanthema	MESH:D005076	marker/mechanism	18176653
C0015230	nevirapine	D019829	129618-40-2	exanthema	MESH:D005076	marker/mechanism	10476768
C0015230	nicotine	D009538	-	exanthema	MESH:D005076	marker/mechanism	10392670
C0015230	nizatidine	D016567	76963-41-2	exanthema	MESH:D005076	marker/mechanism	7769203
C0015230	ofloxacin	D015242	82419-36-1	exanthema	MESH:D005076	marker/mechanism	11131957
C0015230	paclitaxel	D017239	-	exanthema	MESH:D005076	marker/mechanism	10955861
C0015230	phentermine	D010645	122-09-8	exanthema	MESH:D005076	marker/mechanism	9799071
C0015230	phenytoin	D010672	57-41-0	exanthema	MESH:D005076	marker/mechanism	10698845
C0015230	piperacillin	D010878	61477-96-1	exanthema	MESH:D005076	marker/mechanism	2755033
C0015230	prochlorperazine	D011346	58-38-8	exanthema	MESH:D005076	marker/mechanism	4025903
C0015230	propranolol	D011433	525-66-6	exanthema	MESH:D005076	marker/mechanism	1268509
C0015230	propylthiouracil	D011441	51-52-5	exanthema	MESH:D005076	marker/mechanism	15785249
C0015230	sirolimus	D020123	53123-88-9	exanthema	MESH:D005076	marker/mechanism	15102967
C0015230	sorafenib	C471405	-	exanthema	MESH:D005076	marker/mechanism	18796127
C0015230	sulindac	D013467	38194-50-2	exanthema	MESH:D005076	marker/mechanism	7450449
C0015230	temsirolimus	C401859	-	exanthema	MESH:D005076	marker/mechanism	20430774
C0015230	thalidomide	D013792	50-35-1	exanthema	MESH:D005076	marker/mechanism	11840256
C0015230	ticlopidine	D013988	55142-85-3	exanthema	MESH:D005076	marker/mechanism	10453975
C0015230	tramadol	D014147	27203-92-5	exanthema	MESH:D005076	marker/mechanism	12032009
C0015230	trimethoprim	D014295	738-70-5	exanthema	MESH:D005076	marker/mechanism	7481974
C0015230	valproic acid	D014635	99-66-1	exanthema	MESH:D005076	marker/mechanism	15229826
C0015230	vancomycin	D014640	1404-90-6	exanthema	MESH:D005076	marker/mechanism	14742796
C0015230	vincristine	D014750	-	exanthema	MESH:D005076	marker/mechanism	9434832
C0015230	zidovudine	D015215	30516-87-1	exanthema	MESH:D005076	marker/mechanism	11434632

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)