PedAM

Pediatric Disease Annotations & Medicines


	epilepsy

Disease ID	532
Disease	epilepsy
Definition	A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
Synonym	(epilepsy) or (epileptic attack) (epilepsy) or (epileptic attack) (disorder) attack - epileptic attacks epileptic convulsion epileptic disorder epilepsy disorder seizure disorder seizures disorders epileptic disorders seizure disorders seizures ef - epileptic fit ep - epilepsy epilectic attack, nos epilepsia epilepsies epilepsis epilepsy (disorder) epilepsy [disease/finding] epilepsy all types epilepsy nos epilepsy nos (disorder) epilepsy types epilepsy, nos epilepsy, unspecified epileptic epileptic attack epileptic attack, nos epileptic convulsion epileptic convulsions epileptic convulsions, nos epileptic disorder epileptic disorder, nos epileptic fit epileptic fits epileptic fits, nos epileptic seizure epileptic seizure (finding) epileptic seizures epileptic seizures, nos epileptics seizure dis seizure disorder seizure disorder (disorder) seizure disorder nos seizure disorders seizure epileptic seizure syndrome seizure, epileptic seizures syndrome seizures syndromes seizures, epileptic syndrome seizure
DOID	DOID:1826
UMLS	C0014544
MeSH	D004827
SNOMED-CT	SNOMEDCT_US_2016_09_01:128613002;SNOMEDCT_US_2016_09_01:84757009;SNOMEDCT_US_2016_09_01:313307000
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:287) C0011570 \| depression \| 65 C0003467 \| anxiety \| 36 C0025362 \| mental retardation \| 36 C0004352 \| autism \| 35 C0041341 \| tuberous sclerosis \| 32 C0038220 \| status epilepticus \| 27 C0033975 \| psychosis \| 21 C0014544 \| epileptic seizure \| 20 C0014544 \| epileptic seizures \| 18 C0041341 \| tuberous sclerosis complex \| 18 C0149931 \| migraine \| 13 C0004134 \| ataxia \| 13 C0014038 \| encephalitis \| 12 C0342418 \| hypothalamic hamartoma \| 12 C0035372 \| rett syndrome \| 11 C0014556 \| temporal lobe epilepsy \| 11 C0014553 \| absence seizures \| 10 C0007789 \| cerebral palsy \| 10 C0037317 \| sleep disturbance \| 9 C0007758 \| cerebellar ataxia \| 9 C0679466 \| cognitive deficits \| 9 C0497327 \| dementia \| 8 C0037317 \| sleep disturbances \| 8 C0014547 \| focal epilepsy \| 7 C0003469 \| anxiety disorder \| 7 C0026846 \| muscular atrophy \| 7 C0026847 \| spinal muscular atrophy \| 7 C0238111 \| lennox-gastaut syndrome \| 7 C0751122 \| dravet syndrome \| 7 C0042373 \| vascular disease \| 6 C0039614 \| tetanus \| 6 C0003469 \| anxiety disorders \| 6 C0014544 \| epilepsies \| 5 C0011847 \| diabetes \| 5 C0004936 \| mental disorders \| 5 C0018552 \| hamartomas \| 5 C0159020 \| neonatal seizures \| 5 C0751651 \| mitochondrial disease \| 5 C0851578 \| sleep disorders \| 5 C0005586 \| bipolar disorder \| 5 C0033975 \| psychotic disorder \| 5 C1861784 \| cerebral cavernous malformations \| 5 C0342418 \| hypothalamic hamartomas \| 5 C0024141 \| systemic lupus erythematosus \| 5 C0025958 \| microcephaly \| 5 C0009241 \| cognitive disorders \| 4 C0014544 \| epileptic attack \| 4 C0040188 \| tic disorders \| 4 C0020255 \| hydrocephalus \| 4 C0007570 \| celiac disease \| 4 C0014544 \| epilepsy \| 4 C1959589 \| cavernous angioma \| 4 C0010678 \| cysticercosis \| 4 C0018552 \| hamartoma \| 4 C0033975 \| psychoses \| 4 C0037769 \| infantile spasms \| 4 C0026769 \| multiple sclerosis \| 4 C0162635 \| angelman syndrome \| 4 C0013421 \| dystonia \| 4 C0007222 \| cardiovascular disease \| 4 C0409974 \| lupus erythematosus \| 4 C0036341 \| schizophrenia \| 4 C0002395 \| alzheimer's disease \| 4 C0948265 \| metabolic syndrome \| 3 C1266177 \| dysembryoplastic neuroepithelial tumor \| 3 C0014544 \| seizure disorder \| 3 C0037315 \| sleep apnea \| 3 C0034150 \| purpura \| 3 C0029001 \| onchocerciasis \| 3 C0004114 \| astrocytoma \| 3 C0007570 \| coeliac disease \| 3 C0041408 \| turner syndrome \| 3 C1856113 \| mowat-wilson syndrome \| 3 C0033975 \| psychotic disorders \| 3 C0023264 \| leigh syndrome \| 3 C0027765 \| neurological disorder \| 3 C1263846 \| attention deficit hyperactivity disorder \| 3 C0042769 \| viral illness \| 3 C0022716 \| menkes disease \| 3 C0040558 \| toxoplasmosis \| 2 C0268579 \| ketotic hyperglycinemia \| 2 C0027868 \| neuromuscular disease \| 2 C0547030 \| visual disturbances \| 2 C0236792 \| asperger's syndrome \| 2 C0013720 \| ehlers-danlos syndrome \| 2 C0030567 \| parkinson's disease \| 2 C0016667 \| fragile x syndrome \| 2 C0041696 \| major depression \| 2 C0019202 \| wilson's disease \| 2 C0751651 \| mitochondrial disorder \| 2 C0018916 \| angioma \| 2 C0751651 \| mitochondrial diseases \| 2 C0270853 \| juvenile myoclonic epilepsy \| 2 C0751651 \| mitochondrial disorders \| 2 C0028754 \| obesity \| 2 C0033953 \| sexual dysfunction \| 2 C0520679 \| obstructive sleep apnea \| 2 C0547030 \| visual disturbance \| 2 C0021053 \| immune disorders \| 2 C0029456 \| osteoporosis \| 2 C0013384 \| dyskinesia \| 2 C0036439 \| scoliosis \| 2 C0033953 \| sexual disorders \| 2 C0011854 \| type 1 diabetes \| 2 C0524851 \| neurodegenerative disorders \| 2 C1868720 \| periventricular nodular heterotopia \| 2 C0020676 \| hypothyroidism \| 2 C0042870 \| vitamin d deficiency \| 2 C0221355 \| macrocephaly \| 2 C0021053 \| immune disorder \| 2 C0026654 \| moyamoya disease \| 2 C0014547 \| partial epilepsy \| 2 C0042870 \| vitamin d defic \| 2 C0024530 \| malaria \| 2 C0085113 \| neurofibromatosis \| 2 C0019348 \| herpes simplex \| 2 C0030319 \| panic disorder \| 2 C0017636 \| glioblastoma \| 2 C0270850 \| idiopathic generalized epilepsy \| 2 C0023798 \| lipoma \| 2 C0011854 \| type 1 diabetes mellitus \| 2 C0206716 \| gangliogliomas \| 2 C0154723 \| migraine with aura \| 2 C0243010 \| viral encephalitis \| 2 C0023529 \| periventricular leukomalacia \| 2 C0035078 \| renal failure \| 2 C0752120 \| spinocerebellar ataxia type 1 \| 2 C0026654 \| moyamoya \| 2 C0004153 \| atherosclerosis \| 2 C0005940 \| osteopathy \| 1 C0000786 \| spontaneous abortion \| 1 C0042373 \| vascular disorders \| 1 C0004096 \| asthma \| 1 C0023891 \| alcoholic liver cirrhosis \| 1 C0022116 \| ischemia \| 1 C0153633 \| brain cancer \| 1 C0268583 \| methylmalonic acidemia \| 1 C1261175 \| pontocerebellar hypoplasia \| 1 C0014547 \| partial epilepsies \| 1 C0078981 \| arachnoid cyst \| 1 C0037315 \| sleep apnea syndrome \| 1 C0751748 \| non-ketotic hyperglycinemia \| 1 C0020619 \| hypogonadism \| 1 C0266526 \| norrie disease \| 1 C0038522 \| subacute sclerosing panencephalitis \| 1 C0037769 \| west syndrome \| 1 C0042075 \| urological disorders \| 1 C0234166 \| hyperexplexia \| 1 C0007785 \| cerebral infarct \| 1 C0006109 \| chronic enceph \| 1 C0751783 \| lafora disease \| 1 C0004114 \| astrocytic tumor \| 1 C0032460 \| polycystic ovary syndrome \| 1 C0002395 \| alzheimer disease \| 1 C0012546 \| diphtheria \| 1 C0878544 \| cardiomyopathy \| 1 C0019880 \| homocystinuria \| 1 C0018553 \| cowden syndrome \| 1 C0021831 \| bowel disease \| 1 C0007785 \| cerebral infarction \| 1 C0030443 \| periodic paralysis \| 1 C0442874 \| neuropathy \| 1 C0410528 \| skeletal dysplasia \| 1 C0030305 \| pancreatitis \| 1 C0004114 \| astrocytomas \| 1 C0032285 \| pneumonia \| 1 C0149931 \| migraine headaches \| 1 C0011849 \| diabetes mellitus \| 1 C0334583 \| pilocytic astrocytoma \| 1 C0205768 \| subependymal giant cell astrocytoma \| 1 C0014553 \| petit mal seizure \| 1 C0022658 \| nephropathy \| 1 C0015930 \| fetal distress \| 1 C0524851 \| neurodegenerative disease \| 1 C0017205 \| gaucher's disease \| 1 C0152025 \| polyneuropathy \| 1 C0038436 \| post-traumatic stress disorder \| 1 C0011615 \| atopic dermatitis \| 1 C0011854 \| type i diabetes \| 1 C0001339 \| acute pancreatitis \| 1 C0031212 \| personality disorders \| 1 C0041671 \| attention deficit disorder \| 1 C0743039 \| progressive dementia \| 1 C0266463 \| lissencephaly \| 1 C0033375 \| prolactinomas \| 1 C0020598 \| hypoglycaemia \| 1 C0006017 \| pertussis \| 1 C0175695 \| sotos syndrome \| 1 C0205710 \| alpers-huttenlocher syndrome \| 1 C0043325 \| xanthomatosis \| 1 C0206716 \| ganglioglioma \| 1 C0042373 \| vascular disorder \| 1 C0751778 \| progressive myoclonus epilepsy \| 1 C0151620 \| hypertensive encephalopathy \| 1 C0030805 \| pemphigoid \| 1 C0004943 \| behcet's disease \| 1 C0016395 \| focal dermal hypoplasia \| 1 C0011854 \| type i diabetes mellitus \| 1 C0022661 \| chronic renal failure \| 1 C0011334 \| caries \| 1 C0003857 \| arteriovenous malformation \| 1 C1096063 \| intractable epilepsy \| 1 C0039841 \| thiamine deficiency \| 1 C0238052 \| cerebrotendinous xanthomatosis \| 1 C0005586 \| bipolar affective disorder \| 1 C0027765 \| neurologic disorder \| 1 C0042961 \| volvulus \| 1 C0003537 \| aphasia \| 1 C0042769 \| virus infection \| 1 C0027765 \| neurological disease \| 1 C0268128 \| orotic aciduria \| 1 C0023890 \| liver cirrhosis \| 1 C0242350 \| erectile dysfunction \| 1 C0022283 \| hypomelanosis of ito \| 1 C0027051 \| myocardial infarction \| 1 C0041341 \| tuberose sclerosis \| 1 C0175713 \| aicardi syndrome \| 1 C0007820 \| cerebrovascular disorder \| 1 C0002453 \| amenorrhea \| 1 C0162429 \| malnutrition \| 1 C0796004 \| kabuki syndrome \| 1 C0023795 \| urbach-wiethe disease \| 1 C0025286 \| meningioma \| 1 C0268583 \| methylmalonic aciduria \| 1 C0751748 \| nonketotic hyperglycinemia \| 1 C0280793 \| oligoastrocytoma \| 1 C0553662 \| juvenile ra \| 1 C0282512 \| landau-kleffner syndrome \| 1 C1621958 \| glioblastoma multiforme \| 1 C0149931 \| migraine headache \| 1 C0015458 \| parry-romberg syndrome \| 1 C1956097 \| wolf-hirschhorn syndrome \| 1 C0009946 \| conversion disorder \| 1 C0152096 \| trisomy 18 \| 1 C0027765 \| neurological disorders \| 1 C0036323 \| schistosomiasis \| 1 C0014544 \| epilepsia \| 1 C0017205 \| gaucher disease \| 1 C0041696 \| major depressive disorder \| 1 C0270740 \| paroxysmal kinesigenic choreoathetosis \| 1 C0021400 \| influenza \| 1 C0037315 \| sleep apneas \| 1 C0007193 \| dilated cardiomyopathy \| 1 C1720189 \| episodic ataxia \| 1 C0014547 \| localization-related epilepsy \| 1 C0007820 \| cerebrovascular disorders \| 1 C0520679 \| obstructive sleep apnea syndrome \| 1 C0268631 \| succinic semialdehyde dehydrogenase deficiency \| 1 C0023520 \| leukodystrophy \| 1 C0039254 \| taeniasis \| 1 C0178664 \| glomerulosclerosis \| 1 C0030499 \| parasitic disease \| 1 C0220754 \| biotinidase deficiency \| 1 C0027765 \| neurologic disorders \| 1 C0014556 \| temporal lobe epilepsies \| 1 C0027051 \| myocardial infarct \| 1 C0220603 \| pediatric brain tumor \| 1 C0085417 \| complex partial epilepsy \| 1 C0029124 \| optic atrophy \| 1 C0022595 \| darier disease \| 1 C0085543 \| epilepsia partialis continua \| 1 C0023241 \| legionnaire's disease \| 1 C0040560 \| congenital toxoplasmosis \| 1 C0000786 \| spontaneous abortions \| 1 C0011603 \| dermatitis \| 1 C0030499 \| parasitic diseases \| 1 C0006111 \| brain disorders \| 1 C0002871 \| anemia \| 1 C0036454 \| visual field loss \| 1 C0008029 \| cherubism \| 1 C0002895 \| sickle cell anemia \| 1 C0037274 \| cutaneous disorders \| 1 C0175683 \| citrullinemia \| 1 C0006111 \| brain disorder \| 1 C0024534 \| cerebral malaria \| 1 C0743332 \| focal dystonia \| 1 C0013537 \| eclampsia \| 1 C0021390 \| inflammatory bowel disease \| 1 C0238358 \| hypokalemic periodic paralysis \| 1 C0751122 \| severe myoclonic epilepsy in infancy \| 1 C0029408 \| osteoarthritis \| 1 C0456909 \| blindness \| 1 C0042075 \| urological diseases \| 1 C0751265 \| learning disabilities \| 1 C0014060 \| encephalitis c \| 1 C0085541 \| frontal lobe epilepsy \| 1 C0035579 \| rickets \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:191) ABCB1 \| 5243 \| CTD_human SLC2A1 \| 6513 \| UniProtKB-KW CPA6 \| 57094 \| UniProtKB-KW KCNQ2 \| 3785 \| CTD_human;UniProtKB-KW;GHR NPY2R \| 4887 \| CTD_human POMC \| 5443 \| CTD_human GRIN2B \| 2904 \| CTD_human;UniProtKB-KW GRIN2A \| 2903 \| CTD_human;UniProtKB-KW GRIN2D \| 2906 \| UniProtKB-KW ATP2A2 \| 488 \| UniProtKB-KW CACNB4 \| 785 \| UniProtKB-KW;GHR ARX \| 170302 \| UniProtKB-KW;GHR GNAO1 \| 2775 \| UniProtKB-KW QARS \| 5859 \| UniProtKB-KW GRM1 \| 2911 \| CTD_human CHD2 \| 1106 \| CTD_human;UniProtKB-KW ZEB2 \| 9839 \| UniProtKB-KW SCN1A \| 6323 \| CTD_human;GWASCAT;UniProtKB-KW FRRS1L \| 23732 \| UniProtKB-KW CLN5 \| 1203 \| UniProtKB-KW CLN8 \| 2055 \| UniProtKB-KW GPX1 \| 2876 \| CTD_human HCN1 \| 348980 \| CTD_human;UniProtKB-KW PIGA \| 5277 \| UniProtKB-KW SLC1A2 \| 6506 \| CTD_human;UniProtKB-KW SLC1A3 \| 6507 \| CTD_human SLC1A4 \| 6509 \| UniProtKB-KW NPY \| 4852 \| CTD_human ALG13 \| 79868 \| UniProtKB-KW FOLR1 \| 2348 \| CTD_human SCN8A \| 6334 \| CTD_human;UniProtKB-KW CHRNA2 \| 1135 \| UniProtKB-KW CHRNA4 \| 1137 \| UniProtKB-KW SEPSECS \| 51091 \| UniProtKB-KW RELN \| 5649 \| UniProtKB-KW SLC9A6 \| 10479 \| UniProtKB-KW WDR73 \| 84942 \| UniProtKB-KW POLG \| 5428 \| CTD_human;UniProtKB-KW DENND5A \| 23258 \| UniProtKB-KW FLNA \| 2316 \| CTD_human AKT1 \| 207 \| CTD_human ATP6AP2 \| 10159 \| UniProtKB-KW PIGN \| 23556 \| UniProtKB-KW PIGT \| 51604 \| UniProtKB-KW ALB \| 213 \| CTD_human SPTAN1 \| 6709 \| UniProtKB-KW CNTN2 \| 6900 \| UniProtKB-KW MAPK10 \| 5602 \| UniProtKB-KW IER3IP1 \| 51124 \| UniProtKB-KW EPM2A \| 7957 \| UniProtKB-KW;GHR CHRNB2 \| 1141 \| UniProtKB-KW PNKP \| 11284 \| UniProtKB-KW HNRNPU \| 3192 \| UniProtKB-KW MAST4 \| 375449 \| GWASCAT PRICKLE1 \| 144165 \| UniProtKB-KW PRICKLE2 \| 166336 \| UniProtKB-KW UBE3A \| 7337 \| CTD_human SCN1B \| 6324 \| UniProtKB-KW MT-ND1 \| 4535 \| UniProtKB-KW SLC25A22 \| 79751 \| UniProtKB-KW ST3GAL3 \| 6487 \| UniProtKB-KW SLC4A10 \| 57282 \| CTD_human GABRA1 \| 2554 \| UniProtKB-KW;GHR CNNM2 \| 54805 \| UniProtKB-KW SRPX2 \| 27286 \| UniProtKB-KW MEF2C \| 4208 \| CTD_human;UniProtKB-KW ADRA2B \| 151 \| UniProtKB-KW KCNH1 \| 3756 \| CTD_human;UniProtKB-KW TSC1 \| 7248 \| CTD_human;UniProtKB-KW TSC2 \| 7249 \| CTD_human KCNJ10 \| 3766 \| UniProtKB-KW RAB39B \| 116442 \| CTD_human PCDH19 \| 57526 \| CTD_human;UniProtKB-KW CACNA1A \| 773 \| UniProtKB-KW KIF5A \| 3798 \| UniProtKB-KW SCN9A \| 6335 \| UniProtKB-KW TCF4 \| 6925 \| UniProtKB-KW EML1 \| 2009 \| UniProtKB-KW TPP1 \| 1200 \| UniProtKB-KW CAMSAP2 \| 23271 \| GWASCAT AARS \| 16 \| UniProtKB-KW DCX \| 1641 \| UniProtKB-KW SYN1 \| 6853 \| UniProtKB-KW FOS \| 2353 \| CTD_human SYNGAP1 \| 8831 \| CTD_human PCDH7 \| 5099 \| GWASCAT DNM1 \| 1759 \| UniProtKB-KW GABRG2 \| 2566 \| UniProtKB-KW CSTB \| 1476 \| UniProtKB-KW;GHR CAD \| 790 \| UniProtKB-KW KCTD7 \| 154881 \| UniProtKB-KW BDNF \| 627 \| CTD_human CACNA1H \| 8912 \| UniProtKB-KW CACNA1D \| 776 \| UniProtKB-KW FAR1 \| 84188 \| UniProtKB-KW ARHGEF9 \| 23229 \| UniProtKB-KW MTOR \| 2475 \| UniProtKB-KW TBC1D24 \| 57465 \| UniProtKB-KW PRRT2 \| 112476 \| UniProtKB-KW ALDH7A1 \| 501 \| UniProtKB-KW SLC6A1 \| 6529 \| UniProtKB-KW EFHC1 \| 114327 \| UniProtKB-KW;GHR SNIP1 \| 79753 \| UniProtKB-KW ILK \| 3611 \| CTD_human DEPDC5 \| 9681 \| UniProtKB-KW EXT2 \| 2132 \| UniProtKB-KW CNTNAP2 \| 26047 \| CTD_human;UniProtKB-KW FOSB \| 2354 \| CTD_human ATIC \| 471 \| UniProtKB-KW MMP8 \| 4317 \| GWASCAT STX1B \| 112755 \| CTD_human;UniProtKB-KW PTPRD \| 5789 \| GWASCAT DEAF1 \| 10522 \| UniProtKB-KW VDAC2 \| 7417 \| CTD_human SCARB2 \| 950 \| UniProtKB-KW ASAH1 \| 427 \| UniProtKB-KW OPRD1 \| 4985 \| CTD_human FGF12 \| 2257 \| UniProtKB-KW KCNC1 \| 3746 \| UniProtKB-KW CASR \| 846 \| UniProtKB-KW AUTS2 \| 26053 \| CTD_human SLC12A2 \| 6558 \| CTD_human OPRM1 \| 4988 \| CTD_human SLC35A3 \| 23443 \| UniProtKB-KW SIK1 \| 150094 \| UniProtKB-KW ITPA \| 3704 \| UniProtKB-KW GUF1 \| 60558 \| UniProtKB-KW L2HGDH \| 79944 \| CTD_human PHF6 \| 84295 \| UniProtKB-KW UBA5 \| 79876 \| UniProtKB-KW DOCK7 \| 85440 \| UniProtKB-KW LGI1 \| 9211 \| UniProtKB-KW VPS53 \| 55275 \| UniProtKB-KW CCDC88A \| 55704 \| UniProtKB-KW SLC1A1 \| 6505 \| CTD_human PLCB1 \| 23236 \| UniProtKB-KW SCN2A \| 6326 \| CTD_human;UniProtKB-KW LMNB2 \| 84823 \| UniProtKB-KW KCNMA1 \| 3778 \| UniProtKB-KW PROSC \| 11212 \| UniProtKB-KW ERN1 \| 2081 \| CTD_human SPATA5 \| 166378 \| UniProtKB-KW PNPO \| 55163 \| UniProtKB-KW CHRM3 \| 1131 \| GWASCAT SLC35A2 \| 7355 \| UniProtKB-KW CHRM1 \| 1128 \| CTD_human GAL \| 51083 \| UniProtKB-KW NAGA \| 4668 \| UniProtKB-KW CLPB \| 81570 \| UniProtKB-KW CDKL5 \| 6792 \| UniProtKB-KW;GHR CLCN2 \| 1181 \| UniProtKB-KW;GHR GABRB1 \| 2560 \| UniProtKB-KW GABRB3 \| 2562 \| CTD_human;UniProtKB-KW CHRM2 \| 1129 \| CTD_human GFAP \| 2670 \| CTD_human TXNRD1 \| 7296 \| CTD_human SPARCL1 \| 8404 \| CTD_human AP3B2 \| 8120 \| UniProtKB-KW ARV1 \| 64801 \| UniProtKB-KW WWOX \| 51741 \| UniProtKB-KW ADSL \| 158 \| UniProtKB-KW ST3GAL5 \| 8869 \| UniProtKB-KW SZT2 \| 23334 \| UniProtKB-KW ADRA2A \| 150 \| CTD_human KCNA2 \| 3737 \| UniProtKB-KW KCNB1 \| 3745 \| UniProtKB-KW EEF1A2 \| 1917 \| UniProtKB-KW NECAP1 \| 25977 \| UniProtKB-KW GABRD \| 2563 \| UniProtKB-KW;GHR STAMBP \| 10617 \| CTD_human GOSR2 \| 9570 \| UniProtKB-KW BRAT1 \| 221927 \| UniProtKB-KW KCNQ3 \| 3786 \| UniProtKB-KW;GHR KCNAB2 \| 8514 \| CTD_human KCNT1 \| 57582 \| UniProtKB-KW P2RX2 \| 22953 \| CTD_human P2RX4 \| 5025 \| CTD_human ATN1 \| 1822 \| UniProtKB-KW STXBP1 \| 6812 \| UniProtKB-KW VPS13A \| 23230 \| UniProtKB-KW KCND2 \| 3751 \| UniProtKB-KW PRDM8 \| 56978 \| UniProtKB-KW MDH2 \| 4191 \| UniProtKB-KW ROGDI \| 79641 \| UniProtKB-KW SLC12A5 \| 57468 \| CTD_human;UniProtKB-KW NPRL2 \| 10641 \| UniProtKB-KW NPRL3 \| 8131 \| UniProtKB-KW NHLRC1 \| 378884 \| UniProtKB-KW;GHR CERS1 \| 10715 \| UniProtKB-KW DIAPH1 \| 1729 \| UniProtKB-KW VDAC1 \| 7416 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:65) 5243 \| ABCB1 \| infer 1244 \| ABCC2 \| infer 10947 \| AP3M2 \| infer 477 \| ATP1A2 \| infer 627 \| BDNF \| infer 773 \| CACNA1A \| infer 8913 \| CACNA1G \| infer 8912 \| CACNA1H \| infer 8911 \| CACNA1I \| infer 10368 \| CACNG3 \| infer 1135 \| CHRNA2 \| infer 1137 \| CHRNA4 \| infer 1141 \| CHRNB2 \| infer 1181 \| CLCN2 \| infer 26047 \| CNTNAP2 \| infer 1476 \| CSTB \| infer 1544 \| CYP1A2 \| infer 1548 \| CYP2A6 \| infer 1555 \| CYP2B6 \| infer 1557 \| CYP2C19 \| infer 1558 \| CYP2C8 \| infer 1559 \| CYP2C9 \| infer 1576 \| CYP3A4 \| infer 1577 \| CYP3A5 \| infer 1621 \| DBH \| infer 2052 \| EPHX1 \| infer 2550 \| GABBR1 \| infer 2554 \| GABRA1 \| infer 2558 \| GABRA5 \| infer 2560 \| GABRB1 \| infer 2562 \| GABRB3 \| infer 2563 \| GABRD \| infer 2566 \| GABRG2 \| infer 2897 \| GRIK1 \| infer 2914 \| GRM4 \| infer 2944 \| GSTM1 \| infer 2952 \| GSTT1 \| infer 3123 \| HLA-DRB1 \| infer 3240 \| HP \| infer 3553 \| IL1B \| infer 3766 \| KCNJ10 \| infer 3760 \| KCNJ3 \| infer 3763 \| KCNJ6 \| infer 3765 \| KCNJ9 \| infer 27094 \| KCNMB3 \| infer 3785 \| KCNQ2 \| infer 3786 \| KCNQ3 \| infer 10656 \| KHDRBS3 \| infer 163175 \| LGI4 \| infer 4128 \| MAOA \| infer 4524 \| MTHFR \| infer 4548 \| MTR \| infer 4552 \| MTRR \| infer 8856 \| NR1I2 \| infer 4988 \| OPRM1 \| infer 5080 \| PAX6 \| infer 5173 \| PDYN \| infer 10928 \| RALBP1 \| infer 6323 \| SCN1A \| infer 6324 \| SCN1B \| infer 6470 \| SHMT1 \| infer 6508 \| SLC4A3 \| infer 54658 \| UGT1A1 \| infer 54578 \| UGT1A6 \| infer 7364 \| UGT2B7 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:1351) 147429 \| AQP4-AS1 \| DISEASES 147081 \| CRHR1-IT1 \| DISEASES 6405 \| SEMA3F \| DISEASES 10368 \| CACNG3 \| DISEASES 10928 \| RALBP1 \| DISEASES 2554 \| GABRA1 \| DISEASES 84245 \| MRI1 \| DISEASES 65078 \| RTN4R \| DISEASES 340533 \| KIAA2022 \| DISEASES 4826 \| NNAT \| DISEASES 3631 \| INPP4A \| DISEASES 55650 \| PIGV \| DISEASES 3784 \| KCNQ1 \| DISEASES 53615 \| MBD3 \| DISEASES 3385 \| ICAM3 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 4804 \| NGFR \| DISEASES 10947 \| AP3M2 \| DISEASES 9741 \| LAPTM4A \| DISEASES 771 \| CA12 \| DISEASES 9108 \| MTMR7 \| DISEASES 9697 \| TRAM2 \| DISEASES 56131 \| PCDHB4 \| DISEASES 28954 \| REM1 \| DISEASES 343641 \| TGM6 \| DISEASES 23409 \| SIRT4 \| DISEASES 51324 \| SPG21 \| DISEASES 350 \| APOH \| DISEASES 2940 \| GSTA3 \| DISEASES 5603 \| MAPK13 \| DISEASES 28978 \| TMEM14A \| DISEASES 23411 \| SIRT1 \| DISEASES 112755 \| STX1B \| DISEASES 27006 \| FGF22 \| DISEASES 100037417 \| DDTL \| DISEASES 57026 \| PDXP \| DISEASES 3162 \| HMOX1 \| DISEASES 158 \| ADSL \| DISEASES 5816 \| PVALB \| DISEASES 3002 \| GZMB \| DISEASES 328 \| APEX1 \| DISEASES 9362 \| CPNE6 \| DISEASES 1591 \| CYP24A1 \| DISEASES 1917 \| EEF1A2 \| DISEASES 5173 \| PDYN \| DISEASES 5020 \| OXT \| DISEASES 140679 \| SLC32A1 \| DISEASES 1472 \| CST4 \| DISEASES 2742 \| GLRA2 \| DISEASES 7076 \| TIMP1 \| DISEASES 4313 \| MMP2 \| DISEASES 79152 \| FA2H \| DISEASES 9100 \| USP10 \| DISEASES 7249 \| TSC2 \| DISEASES 10273 \| STUB1 \| DISEASES 3163 \| HMOX2 \| DISEASES 6530 \| SLC6A2 \| DISEASES 1666 \| DECR1 \| DISEASES 2936 \| GSR \| DISEASES 4741 \| NEFM \| DISEASES 57030 \| SLC17A7 \| DISEASES 6511 \| SLC1A6 \| DISEASES 973 \| CD79A \| DISEASES 7087 \| ICAM5 \| DISEASES 6822 \| SULT2A1 \| DISEASES 1628 \| DBP \| DISEASES 2057 \| EPOR \| DISEASES 1749 \| DLX5 \| DISEASES 858 \| CAV2 \| DISEASES 6804 \| STX1A \| DISEASES 1577 \| CYP3A5 \| DISEASES 26157 \| GIMAP2 \| DISEASES 2218 \| FKTN \| DISEASES 9570 \| GOSR2 \| DISEASES 55163 \| PNPO \| DISEASES 6198 \| RPS6KB1 \| DISEASES 9487 \| PIGL \| DISEASES 40 \| ASIC2 \| DISEASES 6347 \| CCL2 \| DISEASES 786 \| CACNG1 \| DISEASES 24145 \| PANX1 \| DISEASES 341359 \| SYT10 \| DISEASES 55846 \| ITFG2 \| DISEASES 3458 \| IFNG \| DISEASES 4848 \| CNOT2 \| DISEASES 2597 \| GAPDH \| DISEASES 2026 \| ENO2 \| DISEASES 55907 \| CMAS \| DISEASES 1432 \| MAPK14 \| DISEASES 81491 \| GPR63 \| DISEASES 9896 \| FIG4 \| DISEASES 6908 \| TBP \| DISEASES 1007 \| CDH9 \| DISEASES 2916 \| GRM6 \| DISEASES 51294 \| PCDH12 \| DISEASES 51185 \| CRBN \| DISEASES 10641 \| NPRL2 \| DISEASES 7781 \| SLC30A3 \| DISEASES 5967 \| REG1A \| DISEASES 3485 \| IGFBP2 \| DISEASES 3769 \| KCNJ13 \| DISEASES 3554 \| IL1R1 \| DISEASES 1746 \| DLX2 \| DISEASES 5341 \| PLEK \| DISEASES 1185 \| CLCN6 \| DISEASES 6301 \| SARS \| DISEASES 8574 \| AKR7A2 \| DISEASES 6543 \| SLC8A2 \| DISEASES 9429 \| ABCG2 \| DISEASES 8987 \| STBD1 \| DISEASES 5507 \| PPP1R3C \| DISEASES 3641 \| INSL4 \| DISEASES 56122 \| PCDHB14 \| DISEASES 8600 \| TNFSF11 \| DISEASES 1958 \| EGR1 \| DISEASES 3764 \| KCNJ8 \| DISEASES 2703 \| GJA8 \| DISEASES 847 \| CAT \| DISEASES 4852 \| NPY \| DISEASES 7291 \| TWIST1 \| DISEASES 5552 \| SRGN \| DISEASES 1959 \| EGR2 \| DISEASES 35 \| ACADS \| DISEASES 206358 \| SLC36A1 \| DISEASES 3759 \| KCNJ2 \| DISEASES 5266 \| PI3 \| DISEASES 514 \| ATP5E \| DISEASES 5335 \| PLCG1 \| DISEASES 3991 \| LIPE \| DISEASES 56269 \| IRGC \| DISEASES 26268 \| FBXO9 \| DISEASES 51081 \| MRPS7 \| DISEASES 80255 \| SLC35F5 \| DISEASES 2354 \| FOSB \| DISEASES 64860 \| ARMCX5 \| DISEASES 7389 \| UROD \| DISEASES 7355 \| SLC35A2 \| DISEASES 26030 \| PLEKHG3 \| DISEASES 4974 \| OMG \| DISEASES 821 \| CANX \| DISEASES 391013 \| PLA2G2C \| DISEASES 3315 \| HSPB1 \| DISEASES 51657 \| STYXL1 \| DISEASES 57622 \| LRFN1 \| DISEASES 8484 \| GALR3 \| DISEASES 54982 \| CLN6 \| DISEASES 1315 \| COPB1 \| DISEASES 7166 \| TPH1 \| DISEASES 968 \| CD68 \| DISEASES 6351 \| CCL4 \| DISEASES 599 \| BCL2L2 \| DISEASES 5908 \| RAP1B \| DISEASES 3630 \| INS \| DISEASES 23503 \| ZFYVE26 \| DISEASES 259232 \| NALCN \| DISEASES 7283 \| TUBG1 \| DISEASES 1890 \| TYMP \| DISEASES 348 \| APOE \| DISEASES 1463 \| NCAN \| DISEASES 2056 \| EPO \| DISEASES 3727 \| JUND \| DISEASES 25814 \| ATXN10 \| DISEASES 1968 \| EIF2S3 \| DISEASES 6535 \| SLC6A8 \| DISEASES 23229 \| ARHGEF9 \| DISEASES 2670 \| GFAP \| DISEASES 1327 \| COX4I1 \| DISEASES 10328 \| EMC8 \| DISEASES 8572 \| PDLIM4 \| DISEASES 8500 \| PPFIA1 \| DISEASES 79652 \| TMEM204 \| DISEASES 2521 \| FUS \| DISEASES 57663 \| USP29 \| DISEASES 6538 \| SLC6A11 \| DISEASES 6616 \| SNAP25 \| DISEASES 1401 \| CRP \| DISEASES 4922 \| NTS \| DISEASES 759 \| CA1 \| DISEASES 78986 \| DUSP26 \| DISEASES 11161 \| C14orf1 \| DISEASES 57578 \| UNC79 \| DISEASES 51124 \| IER3IP1 \| DISEASES 3656 \| IRAK2 \| DISEASES 10752 \| CHL1 \| DISEASES 54407 \| SLC38A2 \| DISEASES 60561 \| RINT1 \| DISEASES 2016 \| EMX1 \| DISEASES 27345 \| KCNMB4 \| DISEASES 80896 \| NPL \| DISEASES 5279 \| PIGC \| DISEASES 1593 \| CYP27A1 \| DISEASES 26122 \| EPC2 \| DISEASES 3569 \| IL6 \| DISEASES 2572 \| GAD2 \| DISEASES 9649 \| RALGPS1 \| DISEASES 9568 \| GABBR2 \| DISEASES 347733 \| TUBB2B \| DISEASES 3134 \| HLA-F \| DISEASES 1588 \| CYP19A1 \| DISEASES 6496 \| SIX3 \| DISEASES 1559 \| CYP2C9 \| DISEASES 23314 \| SATB2 \| DISEASES 29081 \| METTL5 \| DISEASES 9360 \| PPIG \| DISEASES 3417 \| IDH1 \| DISEASES 1419 \| CRYGB \| DISEASES 9194 \| SLC16A7 \| DISEASES 6857 \| SYT1 \| DISEASES 3093 \| UBE2K \| DISEASES 5629 \| PROX1 \| DISEASES 23504 \| RIMBP2 \| DISEASES 7597 \| ZBTB25 \| DISEASES 6532 \| SLC6A4 \| DISEASES 59341 \| TRPV4 \| DISEASES 1143 \| CHRNB4 \| DISEASES 80208 \| SPG11 \| DISEASES 10021 \| HCN4 \| DISEASES 23531 \| MMD \| DISEASES 27092 \| CACNG4 \| DISEASES 79726 \| WDR59 \| DISEASES 7434 \| VIPR2 \| DISEASES 3757 \| KCNH2 \| DISEASES 6505 \| SLC1A1 \| DISEASES 56052 \| ALG1 \| DISEASES 6521 \| SLC4A1 \| DISEASES 284058 \| KANSL1 \| DISEASES 6558 \| SLC12A2 \| DISEASES 2775 \| GNAO1 \| DISEASES 9739 \| SETD1A \| DISEASES 5976 \| UPF1 \| DISEASES 7224 \| TRPC5 \| DISEASES 11043 \| MID2 \| DISEASES 25939 \| SAMHD1 \| DISEASES 3783 \| KCNN4 \| DISEASES 2901 \| GRIK5 \| DISEASES 9132 \| KCNQ4 \| DISEASES 5595 \| MAPK3 \| DISEASES 55526 \| DHTKD1 \| DISEASES 22858 \| ICK \| DISEASES 9609 \| RAB36 \| DISEASES 57084 \| SLC17A6 \| DISEASES 6855 \| SYP \| DISEASES 2033 \| EP300 \| DISEASES 55686 \| MREG \| DISEASES 2906 \| GRIN2D \| DISEASES 3553 \| IL1B \| DISEASES 8775 \| NAPA \| DISEASES 9424 \| KCNK6 \| DISEASES 23476 \| BRD4 \| DISEASES 5582 \| PRKCG \| DISEASES 55572 \| FOXRED1 \| DISEASES 25927 \| CNRIP1 \| DISEASES 7301 \| TYRO3 \| DISEASES 10000 \| AKT3 \| DISEASES 3791 \| KDR \| DISEASES 6548 \| SLC9A1 \| DISEASES 8527 \| DGKD \| DISEASES 8942 \| KYNU \| DISEASES 2557 \| GABRA4 \| DISEASES 7531 \| YWHAE \| DISEASES 2892 \| GRIA3 \| DISEASES 57575 \| PCDH10 \| DISEASES 8745 \| ADAM23 \| DISEASES 590 \| BCHE \| DISEASES 8452 \| CUL3 \| DISEASES 2891 \| GRIA2 \| DISEASES 2743 \| GLRB \| DISEASES 9693 \| RAPGEF2 \| DISEASES 2247 \| FGF2 \| DISEASES 27338 \| UBE2S \| DISEASES 6774 \| STAT3 \| DISEASES 84961 \| FBXL20 \| DISEASES 80725 \| SRCIN1 \| DISEASES 83891 \| SNX25 \| DISEASES 5443 \| POMC \| DISEASES 8626 \| TP63 \| DISEASES 3781 \| KCNN2 \| DISEASES 2162 \| F13A1 \| DISEASES 950 \| SCARB2 \| DISEASES 3827 \| KNG1 \| DISEASES 4171 \| MCM2 \| DISEASES 6507 \| SLC1A3 \| DISEASES 64374 \| SIL1 \| DISEASES 6722 \| SRF \| DISEASES 1390 \| CREM \| DISEASES 793 \| CALB1 \| DISEASES 9379 \| NRXN2 \| DISEASES 1181 \| CLCN2 \| DISEASES 4885 \| NPTX2 \| DISEASES 51083 \| GAL \| DISEASES 5243 \| ABCB1 \| DISEASES 53616 \| ADAM22 \| DISEASES 10863 \| ADAM28 \| DISEASES 6595 \| SMARCA2 \| DISEASES 3746 \| KCNC1 \| DISEASES 9044 \| BTAF1 \| DISEASES 22849 \| CPEB3 \| DISEASES 8892 \| EIF2B2 \| DISEASES 429 \| ASCL1 \| DISEASES 6821 \| SUOX \| DISEASES 79944 \| L2HGDH \| DISEASES 59274 \| MESDC1 \| DISEASES 1583 \| CYP11A1 \| DISEASES 3073 \| HEXA \| DISEASES 5428 \| POLG \| DISEASES 18 \| ABAT \| DISEASES 5373 \| PMM2 \| DISEASES 6687 \| SPG7 \| DISEASES 10939 \| AFG3L2 \| DISEASES 4864 \| NPC1 \| DISEASES 7157 \| TP53 \| DISEASES 57332 \| CBX8 \| DISEASES 5211 \| PFKL \| DISEASES 207 \| AKT1 \| DISEASES 6531 \| SLC6A3 \| DISEASES 93650 \| ACPT \| DISEASES 25888 \| ZNF473 \| DISEASES 55917 \| CTTNBP2NL \| DISEASES 3756 \| KCNH1 \| DISEASES 3782 \| KCNN3 \| DISEASES 2052 \| EPHX1 \| DISEASES 5972 \| REN \| DISEASES 805 \| CALM2 \| DISEASES 23233 \| EXOC6B \| DISEASES 165257 \| C1QL2 \| DISEASES 79634 \| SCRN3 \| DISEASES 6508 \| SLC4A3 \| DISEASES 25953 \| PNKD \| DISEASES 51143 \| DYNC1LI1 \| DISEASES 275 \| AMT \| DISEASES 8893 \| EIF2B5 \| DISEASES 58478 \| ENOPH1 \| DISEASES 100996939 \| PYURF \| DISEASES 8001 \| GLRA3 \| DISEASES 2559 \| GABRA6 \| DISEASES 2561 \| GABRB2 \| DISEASES 10667 \| FARS2 \| DISEASES 2041 \| EPHA1 \| DISEASES 57502 \| NLGN4X \| DISEASES 6872 \| TAF1 \| DISEASES 3358 \| HTR2C \| DISEASES 8973 \| CHRNA6 \| DISEASES 2796 \| GNRH1 \| DISEASES 1392 \| CRH \| DISEASES 29967 \| LRP12 \| DISEASES 4915 \| NTRK2 \| DISEASES 4851 \| NOTCH1 \| DISEASES 2746 \| GLUD1 \| DISEASES 64106 \| NPFFR1 \| DISEASES 27315 \| PGAP2 \| DISEASES 6506 \| SLC1A2 \| DISEASES 6327 \| SCN2B \| DISEASES 2904 \| GRIN2B \| DISEASES 161835 \| FSIP1 \| DISEASES 22948 \| CCT5 \| DISEASES 23657 \| SLC7A11 \| DISEASES 3742 \| KCNA6 \| DISEASES 288 \| ANK3 \| DISEASES 79731 \| NARS2 \| DISEASES 5860 \| QDPR \| DISEASES 7082 \| TJP1 \| DISEASES 26040 \| SETBP1 \| DISEASES 5741 \| PTH \| DISEASES 2893 \| GRIA4 \| DISEASES 5013 \| OTX1 \| DISEASES 2697 \| GJA1 \| DISEASES 2911 \| GRM1 \| DISEASES 170692 \| ADAMTS18 \| DISEASES 3192 \| HNRNPU \| DISEASES 5903 \| RANBP2 \| DISEASES 6328 \| SCN3A \| DISEASES 6326 \| SCN2A \| DISEASES 55079 \| FEZF2 \| DISEASES 22878 \| TRAPPC8 \| DISEASES 114791 \| TUBGCP5 \| DISEASES 22934 \| RPIA \| DISEASES 3773 \| KCNJ16 \| DISEASES 8526 \| DGKE \| DISEASES 404550 \| C16orf74 \| DISEASES 4900 \| NRGN \| DISEASES 351 \| APP \| DISEASES 80746 \| TSEN2 \| DISEASES 760 \| CA2 \| DISEASES 761 \| CA3 \| DISEASES 2890 \| GRIA1 \| DISEASES 483 \| ATP1B3 \| DISEASES 132 \| ADK \| DISEASES 4838 \| NODAL \| DISEASES 9131 \| AIFM1 \| DISEASES 6750 \| SST \| DISEASES 6529 \| SLC6A1 \| DISEASES 5468 \| PPARG \| DISEASES 26060 \| APPL1 \| DISEASES 3763 \| KCNJ6 \| DISEASES 84274 \| COQ5 \| DISEASES 56896 \| DPYSL5 \| DISEASES 57477 \| SHROOM4 \| DISEASES 8365 \| HIST1H4H \| DISEASES 3362 \| HTR6 \| DISEASES 50651 \| SLC45A1 \| DISEASES 1142 \| CHRNB3 \| DISEASES 9992 \| KCNE2 \| DISEASES 57369 \| GJD2 \| DISEASES 8659 \| ALDH4A1 \| DISEASES 114771 \| PGLYRP3 \| DISEASES 808 \| CALM3 \| DISEASES 1476 \| CSTB \| DISEASES 7109 \| TRAPPC10 \| DISEASES 5822 \| PWP2 \| DISEASES 10841 \| FTCD \| DISEASES 6285 \| S100B \| DISEASES 55129 \| ANO10 \| DISEASES 1627 \| DBN1 \| DISEASES 2905 \| GRIN2C \| DISEASES 3060 \| HCRT \| DISEASES 162417 \| NAGS \| DISEASES 50944 \| SHANK1 \| DISEASES 1742 \| DLG4 \| DISEASES 84219 \| WDR24 \| DISEASES 57465 \| TBC1D24 \| DISEASES 23498 \| HAAO \| DISEASES 3760 \| KCNJ3 \| DISEASES 4760 \| NEUROD1 \| DISEASES 151473 \| SLC16A14 \| DISEASES 30818 \| KCNIP3 \| DISEASES 27306 \| HPGDS \| DISEASES 2565 \| GABRG1 \| DISEASES 2560 \| GABRB1 \| DISEASES 8320 \| EOMES \| DISEASES 5274 \| SERPINI1 \| DISEASES 213 \| ALB \| DISEASES 166336 \| PRICKLE2 \| DISEASES 57406 \| ABHD6 \| DISEASES 6853 \| SYN1 \| DISEASES 7349 \| UCN \| DISEASES 8927 \| BSN \| DISEASES 327 \| APEH \| DISEASES 256471 \| MFSD8 \| DISEASES 153396 \| TMEM161B \| DISEASES 4724 \| NDUFS4 \| DISEASES 4131 \| MAP1B \| DISEASES 167153 \| PAPD4 \| DISEASES 63974 \| NEUROD6 \| DISEASES 6469 \| SHH \| DISEASES 27012 \| KCNV1 \| DISEASES 114788 \| CSMD3 \| DISEASES 4846 \| NOS3 \| DISEASES 9311 \| ASIC3 \| DISEASES 9907 \| AP5Z1 \| DISEASES 57094 \| CPA6 \| DISEASES 115825 \| WDFY2 \| DISEASES 6571 \| SLC18A2 \| DISEASES 7248 \| TSC1 \| DISEASES 143872 \| ARHGAP42 \| DISEASES 26610 \| ELP4 \| DISEASES 9317 \| PTER \| DISEASES 3990 \| LIPC \| DISEASES 55832 \| CAND1 \| DISEASES 2562 \| GABRB3 \| DISEASES 5092 \| PCBD1 \| DISEASES 79158 \| GNPTAB \| DISEASES 55800 \| SCN3B \| DISEASES 1200 \| TPP1 \| DISEASES 1138 \| CHRNA5 \| DISEASES 2587 \| GALR1 \| DISEASES 29781 \| NCAPH2 \| DISEASES 89832 \| CHRFAM7A \| DISEASES 10369 \| CACNG2 \| DISEASES 6866 \| TAC3 \| DISEASES 26585 \| GREM1 \| DISEASES 1292 \| COL6A2 \| DISEASES 762 \| CA4 \| DISEASES 7846 \| TUBA1A \| DISEASES 1548 \| CYP2A6 \| DISEASES 124936 \| CYB5D2 \| DISEASES 4909 \| NTF4 \| DISEASES 146434 \| ZNF597 \| DISEASES 117245 \| HRASLS5 \| DISEASES 5368 \| PNOC \| DISEASES 81603 \| TRIM8 \| DISEASES 5617 \| PRL \| DISEASES 51305 \| KCNK9 \| DISEASES 203190 \| LGI3 \| DISEASES 478 \| ATP1A3 \| DISEASES 51621 \| KLF13 \| DISEASES 9839 \| ZEB2 \| DISEASES 79663 \| HSPBAP1 \| DISEASES 598 \| BCL2L1 \| DISEASES 3479 \| IGF1 \| DISEASES 3308 \| HSPA4 \| DISEASES 54578 \| UGT1A6 \| DISEASES 43 \| ACHE \| DISEASES 8988 \| HSPB3 \| DISEASES 7200 \| TRH \| DISEASES 83660 \| TLN2 \| DISEASES 6869 \| TACR1 \| DISEASES 6323 \| SCN1A \| DISEASES 53343 \| NUDT9 \| DISEASES 6249 \| CLIP1 \| DISEASES 7804 \| LRP8 \| DISEASES 166614 \| DCLK2 \| DISEASES 7857 \| SCG2 \| DISEASES 1140 \| CHRNB1 \| DISEASES 7064 \| THOP1 \| DISEASES 5028 \| P2RY1 \| DISEASES 375611 \| SLC26A5 \| DISEASES 7364 \| UGT2B7 \| DISEASES 54658 \| UGT1A1 \| DISEASES 5354 \| PLP1 \| DISEASES 9482 \| STX8 \| DISEASES 57555 \| NLGN2 \| DISEASES 79042 \| TSEN34 \| DISEASES 10815 \| CPLX1 \| DISEASES 3954 \| LETM1 \| DISEASES 53944 \| CSNK1G1 \| DISEASES 161725 \| OTUD7A \| DISEASES 2915 \| GRM5 \| DISEASES 2353 \| FOS \| DISEASES 3708 \| ITPR1 \| DISEASES 3777 \| KCNK3 \| DISEASES 7532 \| YWHAG \| DISEASES 7386 \| UQCRFS1 \| DISEASES 79801 \| SHCBP1 \| DISEASES 1128 \| CHRM1 \| DISEASES 3761 \| KCNJ4 \| DISEASES 51029 \| DESI2 \| DISEASES 4761 \| NEUROD2 \| DISEASES 11337 \| GABARAP \| DISEASES 51255 \| RNF181 \| DISEASES 9451 \| EIF2AK3 \| DISEASES 5162 \| PDHB \| DISEASES 4176 \| MCM7 \| DISEASES 794 \| CALB2 \| DISEASES 5859 \| QARS \| DISEASES 11280 \| SCN11A \| DISEASES 54205 \| CYCS \| DISEASES 2752 \| GLUL \| DISEASES 2348 \| FOLR1 \| DISEASES 27289 \| RND1 \| DISEASES 29909 \| GPR171 \| DISEASES 2147 \| F2 \| DISEASES 134 \| ADORA1 \| DISEASES 1540 \| CYLD \| DISEASES 5340 \| PLG \| DISEASES 29925 \| GMPPB \| DISEASES 54715 \| RBFOX1 \| DISEASES 7534 \| YWHAZ \| DISEASES 1808 \| DPYSL2 \| DISEASES 3054 \| HCFC1 \| DISEASES 1072 \| CFL1 \| DISEASES 763 \| CA5A \| DISEASES 3265 \| HRAS \| DISEASES 947 \| CD34 \| DISEASES 8815 \| BANF1 \| DISEASES 23209 \| MLC1 \| DISEASES 54207 \| KCNK10 \| DISEASES 147323 \| STARD6 \| DISEASES 8722 \| CTSF \| DISEASES 836 \| CASP3 \| DISEASES 266743 \| NPAS4 \| DISEASES 200159 \| C1orf100 \| DISEASES 6712 \| SPTBN2 \| DISEASES 57493 \| HEG1 \| DISEASES 27239 \| GPR162 \| DISEASES 132112 \| RTP1 \| DISEASES 5978 \| REST \| DISEASES 4245 \| MGAT1 \| DISEASES 4744 \| NEFH \| DISEASES 7351 \| UCP2 \| DISEASES 163175 \| LGI4 \| DISEASES 1605 \| DAG1 \| DISEASES 78999 \| LRFN4 \| DISEASES 8557 \| TCAP \| DISEASES 64236 \| PDLIM2 \| DISEASES 3952 \| LEP \| DISEASES 51762 \| RAB8B \| DISEASES 124925 \| SEZ6 \| DISEASES 57231 \| SNX14 \| DISEASES 7681 \| MKRN3 \| DISEASES 713 \| C1QB \| DISEASES 6844 \| VAMP2 \| DISEASES 2907 \| GRINA \| DISEASES 998 \| CDC42 \| DISEASES 116068 \| LYSMD3 \| DISEASES 3737 \| KCNA2 \| DISEASES 7915 \| ALDH5A1 \| DISEASES 1191 \| CLU \| DISEASES 151188 \| ARL6IP6 \| DISEASES 1136 \| CHRNA3 \| DISEASES 9495 \| AKAP5 \| DISEASES 3350 \| HTR1A \| DISEASES 8239 \| USP9X \| DISEASES 10170 \| DHRS9 \| DISEASES 246213 \| SLC17A8 \| DISEASES 9478 \| CABP1 \| DISEASES 1960 \| EGR3 \| DISEASES 92609 \| TIMM50 \| DISEASES 114932 \| MRFAP1L1 \| DISEASES 4684 \| NCAM1 \| DISEASES 23621 \| BACE1 \| DISEASES 8630 \| HSD17B6 \| DISEASES 27319 \| BHLHE22 \| DISEASES 377677 \| CA13 \| DISEASES 54984 \| PINX1 \| DISEASES 118442 \| GPR62 \| DISEASES 27094 \| KCNMB3 \| DISEASES 3752 \| KCND3 \| DISEASES 205428 \| C3orf58 \| DISEASES 285195 \| SLC9A9 \| DISEASES 6683 \| SPAST \| DISEASES 4200 \| ME2 \| DISEASES 6863 \| TAC1 \| DISEASES 27133 \| KCNH5 \| DISEASES 1400 \| CRMP1 \| DISEASES 124222 \| PAQR4 \| DISEASES 134957 \| STXBP5 \| DISEASES 23017 \| FAIM2 \| DISEASES 54084 \| TSPEAR \| DISEASES 79751 \| SLC25A22 \| DISEASES 8818 \| DPM2 \| DISEASES 4723 \| NDUFV1 \| DISEASES 6330 \| SCN4B \| DISEASES 547 \| KIF1A \| DISEASES 79641 \| ROGDI \| DISEASES 3355 \| HTR1F \| DISEASES 8243 \| SMC1A \| DISEASES 11284 \| PNKP \| DISEASES 348932 \| SLC6A18 \| DISEASES 6657 \| SOX2 \| DISEASES 51341 \| ZBTB7A \| DISEASES 3309 \| HSPA5 \| DISEASES 5179 \| PENK \| DISEASES 51733 \| UPB1 \| DISEASES 23191 \| CYFIP1 \| DISEASES 1555 \| CYP2B6 \| DISEASES 2932 \| GSK3B \| DISEASES 3735 \| KARS \| DISEASES 64332 \| NFKBIZ \| DISEASES 7025 \| NR2F1 \| DISEASES 148252 \| DIRAS1 \| DISEASES 113457 \| TUBA3D \| DISEASES 54946 \| SLC41A3 \| DISEASES 5663 \| PSEN1 \| DISEASES 4191 \| MDH2 \| DISEASES 80758 \| PRR7 \| DISEASES 2863 \| GPR39 \| DISEASES 283989 \| TSEN54 \| DISEASES 5034 \| P4HB \| DISEASES 3768 \| KCNJ12 \| DISEASES 2055 \| CLN8 \| DISEASES 3739 \| KCNA4 \| DISEASES 1946 \| EFNA5 \| DISEASES 6331 \| SCN5A \| DISEASES 706 \| TSPO \| DISEASES 10456 \| HAX1 \| DISEASES 400451 \| FAM174B \| DISEASES 84295 \| PHF6 \| DISEASES 6906 \| SERPINA7 \| DISEASES 8811 \| GALR2 \| DISEASES 51400 \| PPME1 \| DISEASES 255022 \| CALHM1 \| DISEASES 6656 \| SOX1 \| DISEASES 8224 \| SYN3 \| DISEASES 842 \| CASP9 \| DISEASES 84679 \| SLC9A7 \| DISEASES 9021 \| SOCS3 \| DISEASES 79680 \| C22orf29 \| DISEASES 6900 \| CNTN2 \| DISEASES 402569 \| KPNA7 \| DISEASES 10215 \| OLIG2 \| DISEASES 129804 \| FBLN7 \| DISEASES 56001 \| NXF2 \| DISEASES 29035 \| C16orf72 \| DISEASES 2567 \| GABRG3 \| DISEASES 23545 \| ATP6V0A2 \| DISEASES 162540 \| SPPL2C \| DISEASES 2903 \| GRIN2A \| DISEASES 5813 \| PURA \| DISEASES 90249 \| UNC5A \| DISEASES 80311 \| KLHL15 \| DISEASES 9899 \| SV2B \| DISEASES 6546 \| SLC8A1 \| DISEASES 10052 \| GJC1 \| DISEASES 3916 \| LAMP1 \| DISEASES 8690 \| JRKL \| DISEASES 3751 \| KCND2 \| DISEASES 11212 \| PROSC \| DISEASES 5587 \| PRKD1 \| DISEASES 80258 \| EFHC2 \| DISEASES 170392 \| OIT3 \| DISEASES 10057 \| ABCC5 \| DISEASES 81565 \| NDEL1 \| DISEASES 139886 \| SPIN4 \| DISEASES 8912 \| CACNA1H \| DISEASES 10732 \| TCFL5 \| DISEASES 9456 \| HOMER1 \| DISEASES 401190 \| RGS7BP \| DISEASES 5787 \| PTPRB \| DISEASES 10810 \| WASF3 \| DISEASES 51738 \| GHRL \| DISEASES 60684 \| TRAPPC11 \| DISEASES 2558 \| GABRA5 \| DISEASES 8541 \| PPFIA3 \| DISEASES 885 \| CCK \| DISEASES 80254 \| CEP63 \| DISEASES 8856 \| NR1I2 \| DISEASES 5025 \| P2RX4 \| DISEASES 135 \| ADORA2A \| DISEASES 92335 \| STRADA \| DISEASES 25771 \| TBC1D22A \| DISEASES 4987 \| OPRL1 \| DISEASES 1103 \| CHAT \| DISEASES 3753 \| KCNE1 \| DISEASES 123606 \| NIPA1 \| DISEASES 4842 \| NOS1 \| DISEASES 10011 \| SRA1 \| DISEASES 81614 \| NIPA2 \| DISEASES 1641 \| DCX \| DISEASES 57142 \| RTN4 \| DISEASES 1576 \| CYP3A4 \| DISEASES 3363 \| HTR7 \| DISEASES 554 \| AVPR2 \| DISEASES 23369 \| PUM2 \| DISEASES 23236 \| PLCB1 \| DISEASES 4004 \| LMO1 \| DISEASES 79957 \| PAQR6 \| DISEASES 6622 \| SNCA \| DISEASES 9369 \| NRXN3 \| DISEASES 23583 \| SMUG1 \| DISEASES 9209 \| LRRFIP2 \| DISEASES 2290 \| FOXG1 \| DISEASES 6540 \| SLC6A13 \| DISEASES 5329 \| PLAUR \| DISEASES 84720 \| PIGO \| DISEASES 63826 \| SRR \| DISEASES 221927 \| BRAT1 \| DISEASES 817 \| CAMK2D \| DISEASES 56978 \| PRDM8 \| DISEASES 90139 \| TSPAN18 \| DISEASES 2261 \| FGFR3 \| DISEASES 1180 \| CLCN1 \| DISEASES 54468 \| MIOS \| DISEASES 3985 \| LIMK2 \| DISEASES 1982 \| EIF4G2 \| DISEASES 89910 \| UBE3B \| DISEASES 4128 \| MAOA \| DISEASES 1978 \| EIF4EBP1 \| DISEASES 85440 \| DOCK7 \| DISEASES 4137 \| MAPT \| DISEASES 4208 \| MEF2C \| DISEASES 7225 \| TRPC6 \| DISEASES 113675 \| SDSL \| DISEASES 9324 \| HMGN3 \| DISEASES 344838 \| PAQR9 \| DISEASES 25977 \| NECAP1 \| DISEASES 859 \| CAV3 \| DISEASES 1544 \| CYP1A2 \| DISEASES 1508 \| CTSB \| DISEASES 132884 \| EVC2 \| DISEASES 2066 \| ERBB4 \| DISEASES 7444 \| VRK2 \| DISEASES 9536 \| PTGES \| DISEASES 9031 \| BAZ1B \| DISEASES 11255 \| HRH3 \| DISEASES 3146 \| HMGB1 \| DISEASES 8360 \| HIST1H4D \| DISEASES 22953 \| P2RX2 \| DISEASES 124454 \| EARS2 \| DISEASES 1809 \| DPYSL3 \| DISEASES 5015 \| OTX2 \| DISEASES 54852 \| PAQR5 \| DISEASES 339451 \| KLHL17 \| DISEASES 26053 \| AUTS2 \| DISEASES 2918 \| GRM8 \| DISEASES 3605 \| IL17A \| DISEASES 1499 \| CTNNB1 \| DISEASES 875 \| CBS \| DISEASES 889 \| KRIT1 \| DISEASES 10617 \| STAMBP \| DISEASES 23114 \| NFASC \| DISEASES 31 \| ACACA \| DISEASES 56479 \| KCNQ5 \| DISEASES 144165 \| PRICKLE1 \| DISEASES 144404 \| TMEM120B \| DISEASES 378884 \| NHLRC1 \| DISEASES 4734 \| NEDD4 \| DISEASES 766 \| CA7 \| DISEASES 3767 \| KCNJ11 \| DISEASES 1861 \| TOR1A \| DISEASES 224 \| ALDH3A2 \| DISEASES 54820 \| NDE1 \| DISEASES 6176 \| RPLP1 \| DISEASES 1798 \| DPAGT1 \| DISEASES 9863 \| MAGI2 \| DISEASES 8294 \| HIST1H4I \| DISEASES 4205 \| MEF2A \| DISEASES 10533 \| ATG7 \| DISEASES 6925 \| TCF4 \| DISEASES 6334 \| SCN8A \| DISEASES 4948 \| OCA2 \| DISEASES 51385 \| ZNF589 \| DISEASES 116983 \| ACAP3 \| DISEASES 2335 \| FN1 \| DISEASES 84188 \| FAR1 \| DISEASES 204 \| AK2 \| DISEASES 8363 \| HIST1H4J \| DISEASES 375346 \| TMEM110 \| DISEASES 954 \| ENTPD2 \| DISEASES 50618 \| ITSN2 \| DISEASES 283385 \| MORN3 \| DISEASES 7453 \| WARS \| DISEASES 51760 \| SYT17 \| DISEASES 4010 \| LMX1B \| DISEASES 4983 \| OPHN1 \| DISEASES 6904 \| TBCD \| DISEASES 3359 \| HTR3A \| DISEASES 1785 \| DNM2 \| DISEASES 114785 \| MBD6 \| DISEASES 10656 \| KHDRBS3 \| DISEASES 8368 \| HIST1H4L \| DISEASES 27347 \| STK39 \| DISEASES 273 \| AMPH \| DISEASES 3476 \| IGBP1 \| DISEASES 11152 \| WDR45 \| DISEASES 2555 \| GABRA2 \| DISEASES 23237 \| ARC \| DISEASES 441478 \| NRARP \| DISEASES 1822 \| ATN1 \| DISEASES 3084 \| NRG1 \| DISEASES 781 \| CACNA2D1 \| DISEASES 57194 \| ATP10A \| DISEASES 9463 \| PICK1 \| DISEASES 801 \| CALM1 \| DISEASES 5625 \| PRODH \| DISEASES 1996 \| ELAVL4 \| DISEASES 51114 \| ZDHHC9 \| DISEASES 60 \| ACTB \| DISEASES 9961 \| MVP \| DISEASES 8362 \| HIST1H4K \| DISEASES 23556 \| PIGN \| DISEASES 2917 \| GRM7 \| DISEASES 57835 \| SLC4A5 \| DISEASES 6597 \| SMARCA4 \| DISEASES 121504 \| HIST4H4 \| DISEASES 1510 \| CTSE \| DISEASES 622 \| BDH1 \| DISEASES 2571 \| GAD1 \| DISEASES 4763 \| NF1 \| DISEASES 1524 \| CX3CR1 \| DISEASES 51592 \| TRIM33 \| DISEASES 404552 \| SCGB1D4 \| DISEASES 2996 \| GYPE \| DISEASES 112476 \| PRRT2 \| DISEASES 23271 \| CAMSAP2 \| DISEASES 57642 \| COL20A1 \| DISEASES 23644 \| EDC4 \| DISEASES 8913 \| CACNA1G \| DISEASES 3785 \| KCNQ2 \| DISEASES 5602 \| MAPK10 \| DISEASES 617 \| BCS1L \| DISEASES 23607 \| CD2AP \| DISEASES 9220 \| TIAF1 \| DISEASES 9464 \| HAND2 \| DISEASES 9179 \| AP4M1 \| DISEASES 1999 \| ELF3 \| DISEASES 6539 \| SLC6A12 \| DISEASES 130535 \| KCTD18 \| DISEASES 8359 \| HIST1H4A \| DISEASES 1201 \| CLN3 \| DISEASES 51150 \| SDF4 \| DISEASES 773 \| CACNA1A \| DISEASES 4134 \| MAP4 \| DISEASES 23230 \| VPS13A \| DISEASES 5599 \| MAPK8 \| DISEASES 4133 \| MAP2 \| DISEASES 222553 \| SLC35F1 \| DISEASES 8828 \| NRP2 \| DISEASES 8367 \| HIST1H4E \| DISEASES 1565 \| CYP2D6 \| DISEASES 104 \| ADARB1 \| DISEASES 85315 \| PAQR8 \| DISEASES 140803 \| TRPM6 \| DISEASES 6533 \| SLC6A6 \| DISEASES 80331 \| DNAJC5 \| DISEASES 58484 \| NLRC4 \| DISEASES 4916 \| NTRK3 \| DISEASES 10319 \| LAMC3 \| DISEASES 54981 \| NMRK1 \| DISEASES 1745 \| DLX1 \| DISEASES 477 \| ATP1A2 \| DISEASES 22871 \| NLGN1 \| DISEASES 4519 \| MT-CYB \| DISEASES 2475 \| MTOR \| DISEASES 4508 \| MT-ATP6 \| DISEASES 4886 \| NPY1R \| DISEASES 4541 \| MT-ND6 \| DISEASES 26047 \| CNTNAP2 \| DISEASES 4540 \| MT-ND5 \| DISEASES 1813 \| DRD2 \| DISEASES 4513 \| MT-CO2 \| DISEASES 2705 \| GJB1 \| DISEASES 79674 \| VEPH1 \| DISEASES 1756 \| DMD \| DISEASES 4538 \| MT-ND4 \| DISEASES 5455 \| POU3F3 \| DISEASES 4536 \| MT-ND2 \| DISEASES 56259 \| CTNNBL1 \| DISEASES 56853 \| CELF4 \| DISEASES 116443 \| GRIN3A \| DISEASES 9853 \| RUSC2 \| DISEASES 779 \| CACNA1S \| DISEASES 4537 \| MT-ND3 \| DISEASES 116461 \| TSEN15 \| DISEASES 2913 \| GRM3 \| DISEASES 23038 \| WDTC1 \| DISEASES 1527 \| TEX28 \| DISEASES 7052 \| TGM2 \| DISEASES 1270 \| CNTF \| DISEASES 25893 \| TRIM58 \| DISEASES 6262 \| RYR2 \| DISEASES 27185 \| DISC1 \| DISEASES 8443 \| GNPAT \| DISEASES 5664 \| PSEN2 \| DISEASES 2058 \| EPRS \| DISEASES 7779 \| SLC30A1 \| DISEASES 89796 \| NAV1 \| DISEASES 5110 \| PCMT1 \| DISEASES 5743 \| PTGS2 \| DISEASES 7957 \| EPM2A \| DISEASES 777 \| CACNA1E \| DISEASES 64222 \| TOR3A \| DISEASES 9293 \| GPR52 \| DISEASES 1805 \| DPT \| DISEASES 9287 \| TAAR2 \| DISEASES 3765 \| KCNJ9 \| DISEASES 3766 \| KCNJ10 \| DISEASES 93183 \| PIGM \| DISEASES 10763 \| NES \| DISEASES 632 \| BGLAP \| DISEASES 23208 \| SYT11 \| DISEASES 57657 \| HCN3 \| DISEASES 2173 \| FABP7 \| DISEASES 10654 \| PMVK \| DISEASES 103 \| ADAR \| DISEASES 1141 \| CHRNB2 \| DISEASES 4014 \| LOR \| DISEASES 79005 \| SCNM1 \| DISEASES 10500 \| SEMA6C \| DISEASES 1520 \| CTSS \| DISEASES 1893 \| ECM1 \| DISEASES 23632 \| CA14 \| DISEASES 9900 \| SV2A \| DISEASES 554313 \| HIST2H4B \| DISEASES 8370 \| HIST2H4A \| DISEASES 2018 \| EMX2 \| DISEASES 259217 \| HSPA12A \| DISEASES 26227 \| PHGDH \| DISEASES 116442 \| RAB39B \| DISEASES 1268 \| CNR1 \| DISEASES 4803 \| NGF \| DISEASES 57038 \| RARS2 \| DISEASES 1081 \| CGA \| DISEASES 8517 \| IKBKG \| DISEASES 6566 \| SLC16A1 \| DISEASES 9446 \| GSTO1 \| DISEASES 3738 \| KCNA3 \| DISEASES 3749 \| KCNC4 \| DISEASES 257 \| ALX3 \| DISEASES 9118 \| INA \| DISEASES 2316 \| FLNA \| DISEASES 3351 \| HTR1B \| DISEASES 3654 \| IRAK1 \| DISEASES 22854 \| NTNG1 \| DISEASES 23443 \| SLC35A3 \| DISEASES 79144 \| PPDPF \| DISEASES 1137 \| CHRNA4 \| DISEASES 2556 \| GABRA3 \| DISEASES 115004 \| MB21D1 \| DISEASES 1244 \| ABCC2 \| DISEASES 163351 \| GBP6 \| DISEASES 2334 \| AFF2 \| DISEASES 2332 \| FMR1 \| DISEASES 2258 \| FGF13 \| DISEASES 959 \| CD40LG \| DISEASES 10479 \| SLC9A6 \| DISEASES 653 \| BMP5 \| DISEASES 55227 \| LRRC1 \| DISEASES 5509 \| PPP1R3D \| DISEASES 114327 \| EFHC1 \| DISEASES 29929 \| ALG6 \| DISEASES 1791 \| DNTT \| DISEASES 3725 \| JUN \| DISEASES 1557 \| CYP2C19 \| DISEASES 200008 \| CDCP2 \| DISEASES 9211 \| LGI1 \| DISEASES 6512 \| SLC1A7 \| DISEASES 2902 \| GRIN1 \| DISEASES 7319 \| UBE2A \| DISEASES 3745 \| KCNB1 \| DISEASES 57582 \| KCNT1 \| DISEASES 186 \| AGTR2 \| DISEASES 10564 \| ARFGEF2 \| DISEASES 5728 \| PTEN \| DISEASES 7422 \| VEGFA \| DISEASES 4318 \| MMP9 \| DISEASES 9682 \| KDM4A \| DISEASES 7417 \| VDAC2 \| DISEASES 22845 \| DOLK \| DISEASES 6709 \| SPTAN1 \| DISEASES 728343 \| NXF2B \| DISEASES 1678 \| TIMM8A \| DISEASES 310 \| ANXA7 \| DISEASES 1759 \| DNM1 \| DISEASES 27286 \| SRPX2 \| DISEASES 7105 \| TSPAN6 \| DISEASES 57526 \| PCDH19 \| DISEASES 2899 \| GRIK3 \| DISEASES 27328 \| PCDH11X \| DISEASES 89822 \| KCNK17 \| DISEASES 254065 \| BRWD3 \| DISEASES 6812 \| STXBP1 \| DISEASES 546 \| ATRX \| DISEASES 84253 \| GARNL3 \| DISEASES 54657 \| UGT1A4 \| DISEASES 3208 \| HPCA \| DISEASES 3065 \| HDAC1 \| DISEASES 3061 \| HCRTR1 \| DISEASES 2170 \| FABP3 \| DISEASES 84890 \| ADO \| DISEASES 7099 \| TLR4 \| DISEASES 6572 \| SLC18A3 \| DISEASES 2914 \| GRM4 \| DISEASES 58493 \| INIP \| DISEASES 3710 \| ITPR3 \| DISEASES 1741 \| DLG3 \| DISEASES 7580 \| ZNF32 \| DISEASES 23732 \| FRRS1L \| DISEASES 249 \| ALPL \| DISEASES 8242 \| KDM5C \| DISEASES 2159 \| F10 \| DISEASES 54455 \| FBXO42 \| DISEASES 3303 \| HSPA1A \| DISEASES 7407 \| VARS \| DISEASES 1282 \| COL4A1 \| DISEASES 3055 \| HCK \| DISEASES 1460 \| CSNK2B \| DISEASES 199 \| AIF1 \| DISEASES 2259 \| FGF14 \| DISEASES 1041 \| CDSN \| DISEASES 57348 \| TTYH1 \| DISEASES 26090 \| ABHD12 \| DISEASES 8428 \| STK24 \| DISEASES 7091 \| TLE4 \| DISEASES 4524 \| MTHFR \| DISEASES 3105 \| HLA-A \| DISEASES 55071 \| C9orf40 \| DISEASES 6096 \| RORB \| DISEASES 63908 \| NAPB \| DISEASES 2550 \| GABBR1 \| DISEASES 23670 \| TMEM2 \| DISEASES 1325 \| CORT \| DISEASES 81562 \| LMAN2L \| DISEASES 51629 \| SLC25A39 \| DISEASES 256691 \| MAMDC2 \| DISEASES 1910 \| EDNRB \| DISEASES 8869 \| ST3GAL5 \| DISEASES 5293 \| PIK3CD \| DISEASES 8366 \| HIST1H4B \| DISEASES 765 \| CA6 \| DISEASES 1203 \| CLN5 \| DISEASES 8241 \| RBM10 \| DISEASES 8361 \| HIST1H4F \| DISEASES 1804 \| DPP6 \| DISEASES 8364 \| HIST1H4C \| DISEASES 387509 \| GPR153 \| DISEASES 27253 \| PCDH17 \| DISEASES 5100 \| PCDH8 \| DISEASES 4129 \| MAOB \| DISEASES 8514 \| KCNAB2 \| DISEASES 388585 \| HES5 \| DISEASES 3980 \| LIG3 \| DISEASES 2563 \| GABRD \| DISEASES 8803 \| SUCLA2 \| DISEASES 3356 \| HTR2A \| DISEASES 1114 \| CHGB \| DISEASES 170302 \| ARX \| DISEASES 5080 \| PAX6 \| DISEASES 6339 \| SCNN1D \| DISEASES 5251 \| PHEX \| DISEASES 1906 \| EDN1 \| DISEASES 5621 \| PRNP \| DISEASES 613212 \| CTXN3 \| DISEASES 22866 \| CNKSR2 \| DISEASES 7222 \| TRPC3 \| DISEASES 7223 \| TRPC4 \| DISEASES 5160 \| PDHA1 \| DISEASES 22836 \| RHOBTB3 \| DISEASES 6792 \| CDKL5 \| DISEASES 139105 \| BEND2 \| DISEASES 4810 \| NHS \| DISEASES 317762 \| CCDC85C \| DISEASES 551 \| AVP \| DISEASES 64949 \| MRPS26 \| DISEASES 7280 \| TUBB2A \| DISEASES 670 \| BPHL \| DISEASES 6194 \| RPS6 \| DISEASES 6462 \| SHBG \| DISEASES 10670 \| RRAGA \| DISEASES 3030 \| HADHA \| DISEASES 1183 \| CLCN4 \| DISEASES 1645 \| AKR1C1 \| DISEASES 83605 \| CCM2 \| DISEASES 415 \| ARSE \| DISEASES 7054 \| TH \| DISEASES 9189 \| ZBED1 \| DISEASES 6547 \| SLC8A3 \| DISEASES 105 \| ADARB2 \| DISEASES 6453 \| ITSN1 \| DISEASES 2731 \| GLDC \| DISEASES 51109 \| RDH11 \| DISEASES 427 \| ASAH1 \| DISEASES 169522 \| KCNV2 \| DISEASES 7436 \| VLDLR \| DISEASES 9681 \| DEPDC5 \| DISEASES 55203 \| LGI2 \| DISEASES 26278 \| SACS \| DISEASES 116448 \| OLIG1 \| DISEASES 3736 \| KCNA1 \| DISEASES 4155 \| MBP \| DISEASES 361 \| AQP4 \| DISEASES 9901 \| SRGAP3 \| DISEASES 3786 \| KCNQ3 \| DISEASES 22908 \| SACM1L \| DISEASES 2617 \| GARS \| DISEASES 10716 \| TBR1 \| DISEASES 152992 \| TRMT44 \| DISEASES 6833 \| ABCC8 \| DISEASES 130074 \| FAM168B \| DISEASES 250 \| ALPP \| DISEASES 9290 \| GPR55 \| DISEASES 51347 \| TAOK3 \| DISEASES 11235 \| PDCD10 \| DISEASES 1621 \| DBH \| DISEASES 57628 \| DPP10 \| DISEASES 84628 \| NTNG2 \| DISEASES 5803 \| PTPRZ1 \| DISEASES 2596 \| GAP43 \| DISEASES 92181 \| UBTD2 \| DISEASES 5091 \| PC \| DISEASES 1106 \| CHD2 \| DISEASES 60592 \| SCOC \| DISEASES 5627 \| PROS1 \| DISEASES 26468 \| LHX6 \| DISEASES 89970 \| RSPRY1 \| DISEASES 50801 \| KCNK4 \| DISEASES 79868 \| ALG13 \| DISEASES 2912 \| GRM2 \| DISEASES 56000 \| NXF3 \| DISEASES 83698 \| CALN1 \| DISEASES 6046 \| BRD2 \| DISEASES 9829 \| DNAJC6 \| DISEASES 23475 \| QPRT \| DISEASES 9315 \| NREP \| DISEASES 56666 \| PANX2 \| DISEASES 2737 \| GLI3 \| DISEASES 23096 \| IQSEC2 \| DISEASES 2628 \| GATM \| DISEASES 4338 \| MOCS2 \| DISEASES 3269 \| HRH1 \| DISEASES 64223 \| MLST8 \| DISEASES 23259 \| DDHD2 \| DISEASES 5048 \| PAFAH1B1 \| DISEASES 57471 \| ERMN \| DISEASES 9425 \| CDYL \| DISEASES 10195 \| ALG3 \| DISEASES 4308 \| TRPM1 \| DISEASES 7337 \| UBE3A \| DISEASES 594857 \| NPS \| DISEASES 144577 \| C12orf66 \| DISEASES 4905 \| NSF \| DISEASES 815 \| CAMK2A \| DISEASES 4356 \| MPP3 \| DISEASES 1859 \| DYRK1A \| DISEASES 4363 \| ABCC1 \| DISEASES 7442 \| TRPV1 \| DISEASES 81929 \| SEH1L \| DISEASES 2897 \| GRIK1 \| DISEASES 8131 \| NPRL3 \| DISEASES 23327 \| NEDD4L \| DISEASES 25974 \| MMACHC \| DISEASES 284403 \| WDR62 \| DISEASES 8911 \| CACNA1I \| DISEASES 1135 \| CHRNA2 \| DISEASES 9378 \| NRXN1 \| DISEASES 83873 \| GPR61 \| DISEASES 3033 \| HADH \| DISEASES 3778 \| KCNMA1 \| DISEASES 7018 \| TF \| DISEASES 55041 \| PLEKHB2 \| DISEASES 2570 \| GABRR2 \| DISEASES 55777 \| MBD5 \| DISEASES 93986 \| FOXP2 \| DISEASES 6335 \| SCN9A \| DISEASES 29072 \| SETD2 \| DISEASES 6332 \| SCN7A \| DISEASES 57703 \| CWC22 \| DISEASES 501 \| ALDH7A1 \| DISEASES 27247 \| NFU1 \| DISEASES 151 \| ADRA2B \| DISEASES 3267 \| AGFG1 \| DISEASES 57468 \| SLC12A5 \| DISEASES 1385 \| CREB1 \| DISEASES 8604 \| SLC25A12 \| DISEASES 57571 \| CARNS1 \| DISEASES 132158 \| GLYCTK \| DISEASES 404281 \| YY2 \| DISEASES 352954 \| GATS \| DISEASES 285346 \| ZNF852 \| DISEASES 6336 \| SCN10A \| DISEASES 285175 \| UNC80 \| DISEASES 10903 \| MTMR11 \| DISEASES 5649 \| RELN \| DISEASES 653269 \| POTEI \| DISEASES 89839 \| ARHGAP11B \| DISEASES 57282 \| SLC4A10 \| DISEASES 146713 \| RBFOX3 \| DISEASES 3800 \| KIF5C \| DISEASES 197 \| AHSG \| DISEASES 3776 \| KCNK2 \| DISEASES 4988 \| OPRM1 \| DISEASES 5538 \| PPT1 \| DISEASES 30820 \| KCNIP1 \| DISEASES 4204 \| MECP2 \| DISEASES 6560 \| SLC12A4 \| DISEASES 6329 \| SCN4A \| DISEASES 6324 \| SCN1B \| DISEASES 2898 \| GRIK2 \| DISEASES 5999 \| RGS4 \| DISEASES 4908 \| NTF3 \| DISEASES 83876 \| MRO \| DISEASES 154881 \| KCTD7 \| DISEASES 7124 \| TNF \| DISEASES 6474 \| SHOX2 \| DISEASES 8910 \| SGCE \| DISEASES 387 \| RHOA \| DISEASES 9228 \| DLGAP2 \| DISEASES 3908 \| LAMA2 \| DISEASES 6635 \| SNRPE \| DISEASES 55275 \| VPS53 \| DISEASES 54893 \| MTMR10 \| DISEASES 10715 \| CERS1 \| DISEASES 2593 \| GAMT \| DISEASES 8831 \| SYNGAP1 \| DISEASES 2900 \| GRIK4 \| DISEASES 9465 \| AKAP7 \| DISEASES 79718 \| TBL1XR1 \| DISEASES 9852 \| EPM2AIP1 \| DISEASES 5424 \| POLD1 \| DISEASES 91833 \| WDR20 \| DISEASES 399697 \| CTXN2 \| DISEASES 151295 \| SLC23A3 \| DISEASES 1139 \| CHRNA7 \| DISEASES 284252 \| KCTD1 \| DISEASES 3798 \| KIF5A \| DISEASES 2668 \| GDNF \| DISEASES 8867 \| SYNJ1 \| DISEASES 834 \| CASP1 \| DISEASES 2566 \| GABRG2 \| DISEASES 23658 \| LSM5 \| DISEASES 2632 \| GBE1 \| DISEASES 10900 \| RUNDC3A \| DISEASES 23270 \| TSPYL4 \| DISEASES 389549 \| FEZF1 \| DISEASES 2741 \| GLRA1 \| DISEASES 116 \| ADCYAP1 \| DISEASES 3586 \| IL10 \| DISEASES 6628 \| SNRPB \| DISEASES 2257 \| FGF12 \| DISEASES 627 \| BDNF \| DISEASES 2859 \| GPR35 \| DISEASES 57670 \| KIAA1549 \| DISEASES 1967 \| EIF2B1 \| DISEASES 6513 \| SLC2A1 \| DISEASES 10243 \| GPHN \| DISEASES 5528 \| PPP2R5D \| DISEASES 79813 \| EHMT1 \| DISEASES 9254 \| CACNA2D2 \| DISEASES 132204 \| SYNPR \| DISEASES 266553 \| OFCC1 \| DISEASES 1020 \| CDK5 \| DISEASES 7881 \| KCNAB1 \| DISEASES 51555 \| PEX5L \| DISEASES 5542 \| PRB1 \| DISEASES 6949 \| TCOF1 \| DISEASES 79894 \| ZNF672 \| DISEASES 51428 \| DDX41 \| DISEASES 22987 \| SV2C \| DISEASES 100506742 \| CASP12 \| DISEASES 346007 \| EYS \| DISEASES 10687 \| PNMA2 \| DISEASES 23025 \| UNC13A \| DISEASES 4603 \| MYBL1 \| DISEASES 6586 \| SLIT3 \| DISEASES 3066 \| HDAC2 \| DISEASES 4914 \| NTRK1 \| DISEASES 7178 \| TPT1 \| DISEASES 3748 \| KCNC3 \| DISEASES 9152 \| SLC6A5 \| DISEASES 56140 \| PCDHA8 \| DISEASES 6230 \| RPS25 \| DISEASES 55862 \| ECHDC1 \| DISEASES 785 \| CACNB4 \| DISEASES 488 \| ATP2A2 \| DISEASES 57176 \| VARS2 \| DISEASES 64478 \| CSMD1 \| DISEASES 5099 \| PCDH7 \| DISEASES 5027 \| P2RX7 \| DISEASES 85358 \| SHANK3 \| DISEASES 375612 \| LHFPL3 \| DISEASES 8972 \| MGAM \| DISEASES 1649 \| DDIT3 \| DISEASES 10059 \| DNM1L \| DISEASES 53349 \| ZFYVE1 \| DISEASES 10381 \| TUBB3 \| DISEASES 161436 \| EML5 \| DISEASES 56963 \| RGMA \| DISEASES 9990 \| SLC12A6 \| DISEASES 283953 \| TMEM114 \| DISEASES 91056 \| AP5B1 \| DISEASES 81831 \| NETO2 \| DISEASES 392617 \| ELFN1 \| DISEASES 23334 \| SZT2 \| DISEASES 51741 \| WWOX \| DISEASES 3316 \| HSPB2 \| DISEASES 820 \| CAMP \| DISEASES 22861 \| NLRP1 \| DISEASES 54938 \| SARS2 \| DISEASES 352990 \| HCP5B \| DISEASES 102723508 \| KANTR \| DISEASES 100874251 \| KIRREL3-AS2 \| DISEASES 338799 \| LINC01089 \| DISEASES 378938 \| MALAT1 \| DISEASES 100128977 \| MAPT-AS1 \| DISEASES 100130148 \| MAPT-IT1 \| DISEASES 114614 \| MIR155HG \| DISEASES 4566 \| MT-TK \| DISEASES 4567 \| MT-TL1 \| DISEASES 4570 \| MT-TN \| DISEASES 4574 \| MT-TS1 \| DISEASES 4575 \| MT-TS2 \| DISEASES 7955 \| RNF217-AS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	532
Disease	epilepsy
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:259) HP:0001250 \| Seizures \| 495 HP:0002373 \| Febrile convulsions \| 95 HP:0000716 \| Depression \| 65 HP:0001249 \| Mental retardation \| 58 HP:0002539 \| Cortical dysplasia \| 39 HP:0000708 \| Behavioral problems \| 37 HP:0000739 \| Anxiety \| 36 HP:0000717 \| Autism \| 35 HP:0100543 \| Cognitive deficits \| 34 HP:0007359 \| Partial seizures \| 33 HP:0002133 \| Status epilepticus \| 27 HP:0001631 \| Atria septal defect \| 27 HP:0003200 \| Ragged-red fibers \| 25 HP:0002069 \| Generalized tonic clonic seizures \| 21 HP:0000709 \| Psychosis \| 21 HP:0001263 \| Developmental retardation \| 20 HP:0030692 \| Brain tumor \| 19 HP:0001297 \| Cerebral vascular events \| 16 HP:0002664 \| Neoplasia \| 15 HP:0001298 \| Encephalopathy \| 14 HP:0002315 \| Headaches \| 14 HP:0002076 \| Migraine headaches \| 13 HP:0001251 \| Ataxia \| 12 HP:0010819 \| drop attacks \| 12 HP:0002383 \| Encephalitis \| 12 HP:0002444 \| Hypothalamic hamartoma \| 12 HP:0001268 \| Mental deterioration \| 11 HP:0002197 \| Generalized seizures \| 11 HP:0002121 \| Petit mal seizures \| 11 HP:0009733 \| Glioma \| 11 HP:0007185 \| Loss of consciousness \| 10 HP:0100021 \| Cerebral palsy \| 10 HP:0002360 \| Sleep disturbance \| 9 HP:0000718 \| Aggressive behaviour \| 9 HP:0001337 \| Tremor \| 9 HP:0001336 \| Myoclonic jerks \| 8 HP:0100033 \| Tic disorder \| 8 HP:0000726 \| Dementia \| 8 HP:0003202 \| Neurogenic muscle atrophy, especially in the lower limbs \| 7 HP:0011150 \| Myoclonic absences \| 7 HP:0007269 \| Spinal muscle wasting \| 7 HP:0000078 \| Genital abnormalities \| 6 HP:0002282 \| Heterotopias \| 6 HP:0002529 \| Neuronal loss in central nervous system \| 6 HP:0007302 \| Bipolar disorder \| 6 HP:0000252 \| Small head circumference \| 5 HP:0011157 \| Auras \| 5 HP:0002725 \| Systemic lupus erythematosus \| 5 HP:0012005 \| Deja vu \| 5 HP:0000738 \| Sensory hallucination \| 5 HP:0200134 \| Epileptic encephalopathy \| 5 HP:0002353 \| Abnormal EEG \| 5 HP:0001279 \| Syncope \| 5 HP:0002500 \| Leukoaraiosis \| 5 HP:0002384 \| Dyscognitive seizures \| 5 HP:0011097 \| Salaam convulsions \| 5 HP:0100785 \| Insomnia \| 4 HP:0000238 \| Nonsyndromal hydrocephalus \| 4 HP:0002367 \| Visual hallucinations \| 4 HP:0002354 \| Memory loss \| 4 HP:0000992 \| Skin photosensitivity \| 4 HP:0012531 \| Pain \| 4 HP:0002104 \| Absence of spontaneous respiration \| 4 HP:0001048 \| Cavernous angioma \| 4 HP:0001332 \| Dystonia \| 4 HP:0010566 \| Hamartoma \| 4 HP:0000752 \| Hyperactive behavior \| 4 HP:0100753 \| Schizophrenia \| 4 HP:0002608 \| Celiac disease \| 4 HP:0012469 \| Infantile spasms \| 4 HP:0000729 \| Pervasive developmental disorder \| 3 HP:0002459 \| Dysautonomia \| 3 HP:0010636 \| Schizencephaly \| 3 HP:0000979 \| Purpura \| 3 HP:0002167 \| Speech disorder \| 3 HP:0002027 \| Abdominal pain \| 3 HP:0002376 \| Loss of developmental milestones \| 3 HP:0007018 \| Attention deficits \| 3 HP:0010535 \| Sleep apnea \| 3 HP:0011172 \| Complex febrile seizures \| 3 HP:0002960 \| Autoimmune condition \| 3 HP:0000805 \| Enuresis \| 3 HP:0002621 \| Atherosclerosis \| 2 HP:0002140 \| Ischemic stroke \| 2 HP:0010864 \| Early and severe mental retardation \| 2 HP:0001270 \| Motor retardation \| 2 HP:0000083 \| Renal insufficiency \| 2 HP:0001513 \| Obesity \| 2 HP:0009717 \| Cortical tubers \| 2 HP:0100318 \| Lafora bodies \| 2 HP:0002171 \| Cerebral gliosis \| 2 HP:0012032 \| Lipoma \| 2 HP:0012444 \| Brain wasting \| 2 HP:0100843 \| Glioblastoma \| 2 HP:0000821 \| Underactive thyroid \| 2 HP:0001262 \| Somnolence \| 2 HP:0002018 \| Nausea \| 2 HP:0002269 \| Neuronal migration disorder \| 2 HP:0009592 \| Astrocytoma \| 2 HP:0003470 \| Inability to move \| 2 HP:0100512 \| Vitamin D deficiency \| 2 HP:0002077 \| Migraine with aura \| 2 HP:0002126 \| Polymicrogyria \| 2 HP:0011170 \| Myoclonic atonic seizures \| 2 HP:0002180 \| Neurodegeneration \| 2 HP:0002013 \| Emesis \| 2 HP:0002870 \| Obstructive sleep apnea \| 2 HP:0002521 \| Hypsarrhythmia by EEG \| 2 HP:0008760 \| Violent behavior \| 2 HP:0002084 \| Bifid skull \| 2 HP:0001945 \| Fever \| 2 HP:0001695 \| Cardiac arrest \| 2 HP:0000256 \| Macrocrania \| 2 HP:0001067 \| Neurofibromas \| 2 HP:0002650 \| Scoliosis \| 2 HP:0000939 \| Osteoporosis \| 2 HP:0002901 \| Hypocalcemia \| 2 HP:0011153 \| Focal motor seizures \| 2 HP:0006970 \| Periventricular leukomalacia \| 2 HP:0001269 \| Hemiparesis \| 2 HP:0100660 \| Dyskinesis \| 2 HP:0011665 \| Takotsubo cardiomyopathy \| 2 HP:0003287 \| Abnormality of mitochondrial metabolism \| 2 HP:0000394 \| Lop ear \| 1 HP:0001638 \| Cardiomyopathy \| 1 HP:0002511 \| Late-onset form of familial Alzheimer disease \| 1 HP:0002189 \| Excessive daytime sleepiness \| 1 HP:0001256 \| Mild mental retardation \| 1 HP:0002156 \| High urine homocystine levels \| 1 HP:0003768 \| Periodic paralysis \| 1 HP:0001319 \| Hypotonia, in neonatal onset \| 1 HP:0011158 \| Auditory auras \| 1 HP:0100702 \| Arachnoid cyst \| 1 HP:0012418 \| Low blood oxygen level \| 1 HP:0004305 \| Involuntary muscle contractions \| 1 HP:0001548 \| Overgrowth \| 1 HP:0001266 \| Choreoathetosis \| 1 HP:0001272 \| Cerebellar atrophy \| 1 HP:0002415 \| Degeneration of white matter of brain \| 1 HP:0000141 \| Abnormal absence of menstruation \| 1 HP:0002321 \| Vertigo \| 1 HP:0012817 \| Noncompaction of the ventricular myocardium \| 1 HP:0002758 \| Osteoarthritis \| 1 HP:0007366 \| Brainstem atrophy \| 1 HP:0001649 \| Tachycardia \| 1 HP:0001061 \| Acne \| 1 HP:0000802 \| Erectile dysfunction \| 1 HP:0001335 \| Bimanual synkinesia \| 1 HP:0001342 \| Intracerebral hemorrhage \| 1 HP:0001259 \| Coma \| 1 HP:0007166 \| Paroxysmal dyskinesia \| 1 HP:0012378 \| Fatigue \| 1 HP:0002090 \| Pneumonia \| 1 HP:0002059 \| Degeneration of cerebrum \| 1 HP:0001987 \| Hyperammonemia \| 1 HP:0011162 \| Psychic auras \| 1 HP:0011165 \| Visual auras \| 1 HP:0012075 \| Personality disorder \| 1 HP:0003077 \| Hyperlipidemia \| 1 HP:0000815 \| Primary hypogonadism \| 1 HP:0002099 \| Asthma \| 1 HP:0005086 \| Knee osteoarthritis \| 1 HP:0001735 \| Acute pancreatitis \| 1 HP:0002381 \| Aphasia \| 1 HP:0012847 \| Epilepsia partialis continua \| 1 HP:0012120 \| Methymalonicaciduria \| 1 HP:0000360 \| Ringing in the ears \| 1 HP:0000819 \| Diabetes mellitus \| 1 HP:0006789 \| Mitochondrial encephalopathy \| 1 HP:0011675 \| Arrhythmias \| 1 HP:0002072 \| Chorea \| 1 HP:0006879 \| Pontocerebellar atrophy \| 1 HP:0001733 \| Pancreatic inflammation \| 1 HP:0030214 \| Sex addiction \| 1 HP:0000618 \| Blindness \| 1 HP:0007206 \| Hemimegalencephaly \| 1 HP:0002721 \| Immunodeficiency \| 1 HP:0002652 \| Skeletal dysplasia \| 1 HP:0004395 \| Malnutrition \| 1 HP:0001508 \| Weight faltering \| 1 HP:0000365 \| Hearing impairment \| 1 HP:0001644 \| Congestive cardiomyopathy \| 1 HP:0012668 \| Situational syncope \| 1 HP:0004373 \| Focal dystonia \| 1 HP:0000991 \| Xanthomata \| 1 HP:0002448 \| Progressive encephalopathy \| 1 HP:0002123 \| Myoclonus seizures \| 1 HP:0001658 \| Myocardial infarction \| 1 HP:0001339 \| Lissencephaly \| 1 HP:0012481 \| Developmental Venous Anomaly \| 1 HP:0002154 \| Hyperglycinaemia \| 1 HP:0002912 \| Methylmalonic acidemia \| 1 HP:0003219 \| Ethylmalonic aciduria \| 1 HP:0100723 \| Gastrointestinal stroma tumor \| 1 HP:0001252 \| Hypotonia \| 1 HP:0000135 \| Hypogonadism \| 1 HP:0001399 \| Liver failure \| 1 HP:0003418 \| Back pain \| 1 HP:0002858 \| Mengiomia \| 1 HP:0001518 \| Small for gestational age \| 1 HP:0100022 \| Movement disorder \| 1 HP:0001047 \| Atopic dermatitis \| 1 HP:0012721 \| Venous malformations \| 1 HP:0004308 \| Ventricular arrhythmia \| 1 HP:0001397 \| Hepatic steatosis \| 1 HP:0012758 \| Neurodevelopmental delay \| 1 HP:0005110 \| Atrial fibrillation \| 1 HP:0012174 \| Glioblastoma multiforme \| 1 HP:0011182 \| Epileptiform EEG discharges \| 1 HP:0000670 \| Dental caries \| 1 HP:0001155 \| Hand anomalies \| 1 HP:0002580 \| Volvulus \| 1 HP:0001892 \| Bleeding diathesis \| 1 HP:0000648 \| Optic-nerve degeneration \| 1 HP:0005484 \| Acquired microcephaly \| 1 HP:0002617 \| Aneurysmal dilatation \| 1 HP:0009879 \| Simplified gyral pattern \| 1 HP:0010532 \| Paroxysmal vertigo \| 1 HP:0010526 \| Dysgraphia \| 1 HP:0100026 \| Arteriovenous malformation \| 1 HP:0002748 \| Rickets \| 1 HP:0008765 \| Auditory hallucinations \| 1 HP:0002527 \| Falls \| 1 HP:0001627 \| Congenital heart defects \| 1 HP:0012072 \| Aciduria \| 1 HP:0000725 \| Psychotic episodes \| 1 HP:0002446 \| Astrocytosis \| 1 HP:0001943 \| Hypoglycemia \| 1 HP:0002020 \| Heartburn \| 1 HP:0000028 \| Cryptorchidism \| 1 HP:0000112 \| Nephropathy \| 1 HP:0001321 \| Small cerebellum \| 1 HP:0007373 \| Motor neuron atrophy \| 1 HP:0007105 \| Infantile encephalopathy \| 1 HP:0002411 \| Myokymia \| 1 HP:0001271 \| Polyneuropathy \| 1 HP:0003510 \| Proportionate dwarfism \| 1 HP:0000969 \| Dropsy \| 1 HP:0000096 \| Glomerulosclerosis \| 1 HP:0001941 \| acidemia \| 1 HP:0011450 \| CNS infection \| 1 HP:0011147 \| Typical absence seizures \| 1 HP:0002883 \| Rapid breathing \| 1 HP:0100651 \| Type I diabetes mellitus \| 1 HP:0011972 \| Decreased CSF glucose \| 1 HP:0008358 \| Prolinemia \| 1 HP:0040148 \| Cortical myoclonus \| 1 HP:0008288 \| Nonketotic hyperglycinemia \| 1 HP:0100601 \| Eclampsia \| 1 HP:0000271 \| Abnormal face \| 1 HP:0012229 \| Cerebrospinal fluid pleocytosis \| 1 HP:0010523 \| Alexia \| 1 HP:0001903 \| Anemia \| 1 HP:0012532 \| Chronic pain \| 1 HP:0002239 \| Gastrointestinal hemorrhage \| 1 HP:0003774 \| End-stage renal failure \| 1 HP:0002902 \| Hyponatremia \| 1 HP:0005268 \| Spontaneous abortion \| 1 HP:0002584 \| Intestinal hemorrhage \| 1

Disease ID	532
Disease	epilepsy
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:114) C0036572 \| seizures \| 334 C0036572 \| seizure \| 157 C1504404 \| hippocampal sclerosis \| 147 C0011570 \| depression \| 65 C0003467 \| anxiety \| 36 C0431380 \| cortical dysplasia \| 36 C0025362 \| mental retardation \| 34 C0277787 \| stigma \| 34 C0033975 \| psychosis \| 20 C0014544 \| epileptic seizures \| 18 C0038454 \| stroke \| 16 C0149931 \| migraine \| 13 C0751495 \| partial seizures \| 13 C0086132 \| depressive symptoms \| 13 C0235169 \| excitability \| 13 C0014038 \| encephalitis \| 11 C0004134 \| ataxia \| 11 C0748607 \| recurrent seizures \| 11 C0796095 \| c syndrome \| 10 C0342418 \| hypothalamic hamartoma \| 9 C0270846 \| atonic seizures \| 9 C0679466 \| cognitive deficits \| 9 C0040822 \| tremor \| 9 C0018681 \| headache \| 8 C0497327 \| dementia \| 7 C0027066 \| myoclonus \| 7 C0522224 \| palsy \| 7 C0003469 \| anxiety disorders \| 6 C0037317 \| sleep disturbance \| 6 C0004936 \| mental disorders \| 5 C0234428 \| impaired consciousness \| 5 C0018524 \| hallucinations \| 5 C0262405 \| brain dysfunction \| 5 C0149958 \| complex partial seizures \| 5 C0206715 \| neuroepithelial tumor \| 4 C0231303 \| distress \| 4 C0009241 \| cognitive disorders \| 4 C0040188 \| tic disorders \| 4 C0871189 \| psychotic symptoms \| 4 C0007570 \| celiac disease \| 4 C0005586 \| bipolar disorder \| 4 C0007222 \| cardiovascular disease \| 4 C0010678 \| cysticercosis \| 4 C0036341 \| schizophrenia \| 4 C0013421 \| dystonia \| 4 C0342418 \| hypothalamic hamartomas \| 3 C0037317 \| sleep disturbances \| 3 C0431380 \| cortical dysplasias \| 3 C2676454 \| h syndrome \| 3 C0020255 \| hydrocephalus \| 3 C0001726 \| affective symptoms \| 3 C1263846 \| attention deficit hyperactivity disorder \| 3 C0233401 \| psychiatric symptom \| 3 C0851578 \| sleep disorders \| 3 C0751494 \| convulsive seizures \| 3 C0037315 \| sleep apnea \| 3 C0221505 \| brain lesions \| 3 C0027765 \| neurological disorder \| 3 C0851578 \| sleep disorder \| 2 C0036857 \| severe mental retardation \| 2 C0547030 \| visual disturbances \| 2 C0033953 \| sexual disorder \| 2 C0152128 \| drug withdrawal \| 2 C0033975 \| psychotic disorders \| 2 C0041696 \| major depression \| 2 C0520679 \| obstructive sleep apnea \| 2 C0002622 \| amnesia \| 2 C0004153 \| atherosclerosis \| 2 C0422943 \| visual symptoms \| 2 C1739395 \| takotsubo cardiomyopathy \| 2 C0233401 \| psychiatric symptoms \| 2 C0042870 \| vitamin d deficiency \| 2 C0033953 \| sexual dysfunction \| 2 C0017638 \| gliomas \| 2 C1837249 \| neuronal migration disorder \| 2 C0033975 \| psychoses \| 2 C0393734 \| complex partial status epilepticus \| 2 C0235946 \| brain atrophy \| 2 C0024530 \| malaria \| 2 C1720983 \| channelopathy \| 1 C0740279 \| cerebellar atrophy \| 1 C0270862 \| hemiplegic migraine \| 1 C0751265 \| learning disabilities \| 1 C0018916 \| angiomas \| 1 C0549117 \| frontal lobe syndrome \| 1 C0235946 \| cerebral atrophy \| 1 C0042963 \| vomiting \| 1 C0026650 \| movement disorders \| 1 C0038454 \| strokes \| 1 C0262405 \| cerebral dysfunction \| 1 C0238421 \| selenium deficiency \| 1 C0025517 \| metabolic disorder \| 1 C0009951 \| convulsions \| 1 C0003537 \| aphasia \| 1 C0021051 \| immunodeficiency \| 1 C0022116 \| ischemia \| 1 C0042961 \| volvulus \| 1 C0078981 \| arachnoid cyst \| 1 C0029166 \| oral manifestations \| 1 C0221163 \| motor disorders \| 1 C0694563 \| excessive daytime sleepiness \| 1 C0743039 \| progressive dementia \| 1 C0233895 \| hyposexuality \| 1 C0013363 \| dysautonomia \| 1 C0442874 \| neuropathy \| 1 C0221503 \| insanity \| 1 C0233762 \| auditory hallucinations \| 1 C1848213 \| bilateral periventricular nodular heterotopia \| 1 C0005940 \| osteopathy \| 1 C0032460 \| polycystic ovary syndrome \| 1 C0009951 \| convulsion \| 1 C0020625 \| hyponatremia \| 1 C0041107 \| trisomy \| 1 C0031212 \| personality disorders \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:144)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1044352	25087078	5099	PCDH7	umls:C0014544	GWASCAT	Meta-analysis of the all-epilepsy cohort identified loci at 2q24.3 (p=8·71 × 10(-10)), implicating SCN1A, and at 4p15.1 (p=5·44 × 10(-9)), harbouring PCDH7, which encodes a protocadherin molecule not previously implicated in epilepsy.	0.120271442	2014	PCDH7	4	31146252	G	A,C,T
rs1045642	23984379	1577	CYP3A5	umls:C0014544	BeFree	The study failed to corroborate association between polymorphism CYP3A5*3 and C3435T polymorphism in MDR1 gene and pharmacoresistant epilepsy.	0.002909916	2013	ABCB1	7	87509329	A	T,G
rs1045642	24213830	5243	ABCB1	umls:C0014544	BeFree	The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children.	0.194338987	2013	ABCB1	7	87509329	A	T,G
rs1045642	24553780	5243	ABCB1	umls:C0014544	BeFree	All the case-control association researches evaluating the role of MDR1 C3435T polymorphism in childhood epilepsy to antiepileptic drugs were identified.	0.194338987	2014	ABCB1	7	87509329	A	T,G
rs1045642	25223475	5243	ABCB1	umls:C0014544	BeFree	The aim of our study was to investigate the relationship between C3435T polymorphism of the MDR1 gene and drug resistance in epilepsy with the consideration of 4 different criteria for qualification to groups sensitive and resistant to applied pharmacotherapy.	0.194338987	2015	ABCB1	7	87509329	A	T,G
rs1045642	20605481	5243	ABCB1	umls:C0014544	BeFree	ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis.	0.194338987	2010	ABCB1	7	87509329	A	T,G
rs1045642	25846690	5243	ABCB1	umls:C0014544	BeFree	Association of ABCB1 C3435T polymorphism with phenobarbital resistance in Thai patients with epilepsy.	0.194338987	2015	ABCB1	7	87509329	A	T,G
rs1045642	19178561	5243	ABCB1	umls:C0014544	BeFree	We included all published studies until September 2007, in which patients with responsive and unresponsive seizure disorders underwent genotyping for ABCB1 C3435T.	0.194338987	2009	ABCB1	7	87509329	A	T,G
rs1045642	15857428	5243	ABCB1	umls:C0014544	BeFree	This study failed to corroborate a previously reported association between the C3435T polymorphism in the human MDR1 gene and pharmacoresistant epilepsy.	0.194338987	2005	ABCB1	7	87509329	A	T,G
rs1045642	24300029	5243	ABCB1	umls:C0014544	BeFree	Significance of MDR1 gene polymorphism C3435T in predicting drug response in epilepsy.	0.194338987	2013	ABCB1	7	87509329	A	T,G
rs1045642	22239287	5243	ABCB1	umls:C0014544	BeFree	Role of MDR1 C3435T and GABRG2 C588T gene polymorphisms in seizure occurrence and MDR1 effect on anti-epileptic drug (phenytoin) absorption.	0.194338987	2012	ABCB1	7	87509329	A	T,G
rs1045642	17917461	5243	ABCB1	umls:C0014544	BeFree	Association of MDR1 (C3435T) polymorphism and resistance to carbamazepine in epileptic patients from Turkey.	0.194338987	2008	ABCB1	7	87509329	A	T,G
rs1045642	16542858	5243	ABCB1	umls:C0014544	BeFree	Lack of association between C3435T nucleotide MDR1 genetic polymorphism and multidrug-resistant epilepsy.	0.194338987	2006	ABCB1	7	87509329	A	T,G
rs1045642	23984379	5243	ABCB1	umls:C0014544	BeFree	The study failed to corroborate association between polymorphism CYP3A5*3 and C3435T polymorphism in MDR1 gene and pharmacoresistant epilepsy.	0.194338987	2013	ABCB1	7	87509329	A	T,G
rs1045642	23465586	5243	ABCB1	umls:C0014544	BeFree	Multidrug resistance 1 (MDR1) 3435C/T genotyping in childhood drug-resistant epilepsy.	0.194338987	2013	ABCB1	7	87509329	A	T,G
rs1045642	24794827	5243	ABCB1	umls:C0014544	BeFree	Previous studies have attempted to confirm the association between the ABCB1-C3435T polymorphism and drug-resistant epilepsy and produced discordant findings.	0.194338987	2014	ABCB1	7	87509329	A	T,G
rs1045642	22239287	2566	GABRG2	umls:C0014544	BeFree	To assess the role of MDR1 and gamma-aminobutyric acid receptor-gamma 2 sub unit (GABRG2) gene polymorphism in seizure susceptibility in generalized seizure (GS) and febrile seizure (FS) patients and to evaluate MDR1 C3435T gene polymorphism's role in absorption of the anti-epileptic drug, phenytoin (PHT) in a cohort of patients.	0.017806881	2012	ABCB1	7	87509329	A	T,G
rs1045642	25799371	5243	ABCB1	umls:C0014544	BeFree	ABCB1 gene C3435T polymorphism and drug resistance in epilepsy: evidence based on 8,604 subjects.	0.194338987	2015	ABCB1	7	87509329	A	T,G
rs1045642	19167193	5243	ABCB1	umls:C0014544	BeFree	Studies on epilepsy have focused on the C3435T polymorphism of the ABCB1 gene, but other ABC transporters are also thought to be involved in the transport of antiepileptic drugs.	0.194338987	2009	ABCB1	7	87509329	A	T,G
rs1045642	17521963	5243	ABCB1	umls:C0014544	BeFree	Association between ABCB1 C3435T polymorphism and drug-resistant epilepsy in Han Chinese.	0.194338987	2007	ABCB1	7	87509329	A	T,G
rs1045642	24953225	5243	ABCB1	umls:C0014544	BeFree	The relationship established in a subset of the Chinese population between the MDR1 C3435T polymorphism and refractory epilepsy will guide epilepsy treatment and development of new AEDs.	0.194338987	2014	ABCB1	7	87509329	A	T,G
rs104894718	21994374	6324	SCN1B	umls:C0014544	BeFree	In contrast, two other SCN1B mutations associated with epilepsy, p.C121W and p.R85H, are expressed at the cell surface.	0.01482102	2011	SCN1B	19	35033654	C	G,T
rs1128503	21079659	5243	ABCB1	umls:C0014544	BeFree	Association between ABCB1-T1236C polymorphism and drug-resistant epilepsy in Iranian female patients.	0.194338987	2010	ABCB1	7	87550285	A	G
rs1130183	23965030	3766	KCNJ10	umls:C0014544	BeFree	It was also observed that the variant, p.Arg271Cys in KCNJ10, previously thought to have a protective effect against seizure susceptibility, was found in a patient with Pendred syndrome with co-existing epilepsy.	0.005624334	2013	KCNJ10	1	160041722	G	A
rs113994049	18005052	8893	EIF2B5	umls:C0014544	BeFree	Pregnancy was complicated by a non-convulsive epileptic status leading to the identification of compound heterozygous EIF2B5 mutation (p.Arg113His and p.Arg299His).	0.000271442	2008	EIF2B5	3	184137637	G	A
rs113994060	18005052	8893	EIF2B5	umls:C0014544	BeFree	Pregnancy was complicated by a non-convulsive epileptic status leading to the identification of compound heterozygous EIF2B5 mutation (p.Arg113His and p.Arg299His).	0.000271442	2008	EIF2B5	3	184140470	G	A
rs113994095	21515089	5428	POLG	umls:C0014544	BeFree	Treatment of epilepsy in patients with a POLG1 compound heterozygous A467T/W748S genotype is very challenging; the epilepsy may preferentially respond to sodium channel blockers.	0.122985861	2011	POLG;MIR6766	15	89327201	C	T
rs113994097	21515089	5428	POLG	umls:C0014544	BeFree	Treatment of epilepsy in patients with a POLG1 compound heterozygous A467T/W748S genotype is very challenging; the epilepsy may preferentially respond to sodium channel blockers.	0.122985861	2011	POLG	15	89323426	C	G
rs115716690	20022885	3767	KCNJ11	umls:C0014544	BeFree	We report two novel mutations on the same haplotype (cis), F60Y and V64L, in the slide helix of Kir6.2 in a patient with neonatal diabetes, developmental delay and epilepsy.	0.010344586	2010	KCNJ11	11	17387902	C	A
rs118192207	18246739	3785	KCNQ2	umls:C0014544	BeFree	The absence of the mutation both in the healthy members of the family and in a control group, and the lack of any other change in the KCNQ2 gene of the patients indicate that N258S substitution is a pathogenic mutation leading to epileptic seizures in this family.	0.140030617	2007	KCNQ2	20	63442449	T	C
rs118192249	18425618	3786	KCNQ3	umls:C0014544	BeFree	Altered KCNQ3 potassium channel function caused by the W309R pore-helix mutation found in human epilepsy.	0.008967513	2008	KCNQ3	8	132175461	A	G
rs11890028	22949513	6323	SCN1A	umls:C0014544	BeFree	Suggestive evidence for an association with GGEs was found in the region 2q24.3 (rs11890028, P(meta) = 4.0 × 10(-6)) nearby the SCN1A gene, which is currently the gene with the largest number of known epilepsy-related mutations.	0.323466984	2012	SCN1A;LOC101929680	2	166086767	T	G
rs119488099	21504429	9211	LGI1	umls:C0014544	BeFree	We found two pathogenic LGI1 mutations with uncommonly low penetrance: the R136W mutation, previously detected in a sporadic case with telephone-induced partial seizures, gave rise to the epileptic phenotype in three of nine mutation carriers in one family; the novel C179R mutation caused epilepsy in an isolated patient from a family where the mutation segregated.	0.015687547	2011	LGI1;LOC105378437	10	93777592	C	T
rs12059546	22949513	1131	CHRM3	umls:C0014544	GWASCAT	Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32.	0.120271442	2012	CHRM3	1	239806797	A	G
rs121434610	18550699	6611	SMS	umls:C0014544	BeFree	This missense mutation, p.G56S, greatly reduces SMS activity and leads to severe epilepsy and cognitive impairment.	0.000271442	2008	SMS	X	21967312	G	A
rs121909674	26005849	2566	GABRG2	umls:C0014544	BeFree	The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration.	0.017806881	2015	GABRG2	5	162153132	C	T
rs121918622	21156207	6334	SCN8A	umls:C0014544	BeFree	Our results demonstrate that variants in Scn2a, Kcnq2, and Scn8a can dramatically influence the phenotype of mice carrying the Scn1a-R1648H mutation and suggest that ion channel variants may contribute to the clinical variation seen in patients with monogenic epilepsy.	0.124071628	2011	SCN1A;LOC102724058	2	165992332	C	T,A
rs121918622	21156207	3785	KCNQ2	umls:C0014544	BeFree	Our results demonstrate that variants in Scn2a, Kcnq2, and Scn8a can dramatically influence the phenotype of mice carrying the Scn1a-R1648H mutation and suggest that ion channel variants may contribute to the clinical variation seen in patients with monogenic epilepsy.	0.140030617	2011	SCN1A;LOC102724058	2	165992332	C	T,A
rs121918622	25378155	6323	SCN1A	umls:C0014544	BeFree	Here, we present a multisystem analysis of an SCN1A mouse model carrying the NaV1.1-R1648H mutation, which causes febrile seizures and epilepsy in humans.	0.323466984	2015	SCN1A;LOC102724058	2	165992332	C	T,A
rs121918622	21156207	6323	SCN1A	umls:C0014544	BeFree	Our results demonstrate that variants in Scn2a, Kcnq2, and Scn8a can dramatically influence the phenotype of mice carrying the Scn1a-R1648H mutation and suggest that ion channel variants may contribute to the clinical variation seen in patients with monogenic epilepsy.	0.323466984	2011	SCN1A;LOC102724058	2	165992332	C	T,A
rs121918628	16054936	6323	SCN1A	umls:C0014544	BeFree	Sequencing of candidate genes in this region revealed a heterozygous missense mutation (Gln1489Lys) in the neuronal voltage-gated sodium channel gene SCN1A, mutations of which have been associated with epilepsy.	0.323466984	2005	SCN1A;LOC102724058	2	165998049	G	T
rs121918799	23398611	6323	SCN1A	umls:C0014544	BeFree	To report the identification of the T1174S SCN1A (NaV 1.1) mutation in a three-generation family with both epileptic and familial hemiplegic migraine (FHM) phenotypes and clarify the pathomechanism.	0.323466984	2013	SCN1A;LOC102724058	2	166015636	G	C
rs122460159	17993579	6792	CDKL5	umls:C0014544	BeFree	We screened the entire coding region of CDKL5 in 151 affected girls with a clinically heterogeneous phenotype ranging from encephalopathy with epilepsy to atypical Rett syndrome by denaturing high liquid performance chromatography and direct sequencing, and we identified three novel missense mutations located in catalytic domain (p.Ala40Val, p.Arg65Gln, p.Leu220Pro).	0.02005048	2008	CDKL5	X	18564496	C	T
rs12912233	25668517	6323	SCN1A	umls:C0014544	BeFree	RORA gene rs12912233 and rs880626 polymorphisms and their interaction with SCN1A rs3812718 in the risk of epilepsy: a case-control study in Malaysia.	0.323466984	2015	RORA	15	60974897	C	T
rs12912233	25668517	6095	RORA	umls:C0014544	BeFree	RORA gene rs12912233 and rs880626 polymorphisms and their interaction with SCN1A rs3812718 in the risk of epilepsy: a case-control study in Malaysia.	0.000271442	2015	RORA	15	60974897	C	T
rs12987787	25087078	6323	SCN1A	umls:C0014544	GWASCAT	Meta-analysis of the all-epilepsy cohort identified loci at 2q24.3 (p=8·71 × 10(-10)), implicating SCN1A, and at 4p15.1 (p=5·44 × 10(-9)), harbouring PCDH7, which encodes a protocadherin molecule not previously implicated in epilepsy.	0.323466984	2014	SCN1A;LOC102724058	2	166001881	T	C
rs12987787	25087078	102724058	LOC102724058	umls:C0014544	GWASCAT	Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies.	0.12	2014	SCN1A;LOC102724058	2	166001881	T	C
rs13026414	22949513	101927235	LOC101927235	umls:C0014544	GWASCAT	Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32.	0.12	2012	LOC101927235;LOC105377629;LOC105377630;LOC105377632	2	57706920	C	T
rs149055334	25489633	114327	EFHC1	umls:C0014544	BeFree	Public databases also show that the EFHC1 P77T-R221H JME haplotype is present in unphenotyped West African ancestry populations, and we show that it can be found at appreciable frequency in healthy individuals with no family history of epilepsy.	0.004895885	2014	EFHC1	6	52424111	C	A
rs1611115	22881836	1621	DBH	umls:C0014544	BeFree	Stage 1 analysis included 290 patients with epilepsy and revealed a higher load of adverse psychotropic side effects of LEV in patients carrying genetic variants associated with decreased dopaminergic activity: rs1611115 (dopamine-β-hydroxylase, DBH), rs4680 (catechol-O-methyltransferase, COMT), and rs1800497 (dopamine receptor D2-associated ANKK1 TAQ-1A).	0.000271442	2013	DBH	9	133635393	T	C
rs1611115	22881836	1312	COMT	umls:C0014544	BeFree	Stage 1 analysis included 290 patients with epilepsy and revealed a higher load of adverse psychotropic side effects of LEV in patients carrying genetic variants associated with decreased dopaminergic activity: rs1611115 (dopamine-β-hydroxylase, DBH), rs4680 (catechol-O-methyltransferase, COMT), and rs1800497 (dopamine receptor D2-associated ANKK1 TAQ-1A).	0.000271442	2013	DBH	9	133635393	T	C
rs16944	22578659	3569	IL6	umls:C0014544	BeFree	To understand the role of genes encoding pro-inflammatory cytokines in epilepsy, this study aimed to evaluate the polymorphisms of the promoter regions of IL-1β-511C>T (rs16944), TNF-α-308G>A (rs1800629) and IL-6-174G>C (rs1800795) genes and to look into the interaction between these genes in influencing seizure susceptibility, seizure frequency and response to therapy.	0.001357209	2012	IL1B	2	112837290	A	G
rs16944	22578659	3553	IL1B	umls:C0014544	BeFree	To understand the role of genes encoding pro-inflammatory cytokines in epilepsy, this study aimed to evaluate the polymorphisms of the promoter regions of IL-1β-511C>T (rs16944), TNF-α-308G>A (rs1800629) and IL-6-174G>C (rs1800795) genes and to look into the interaction between these genes in influencing seizure susceptibility, seizure frequency and response to therapy.	0.002442977	2012	IL1B	2	112837290	A	G
rs16969925	21994374	6324	SCN1B	umls:C0014544	BeFree	In contrast, two other SCN1B mutations associated with epilepsy, p.C121W and p.R85H, are expressed at the cell surface.	0.01482102	2011	SCN1B	19	35033545	G	A
rs1800497	22881836	1621	DBH	umls:C0014544	BeFree	Stage 1 analysis included 290 patients with epilepsy and revealed a higher load of adverse psychotropic side effects of LEV in patients carrying genetic variants associated with decreased dopaminergic activity: rs1611115 (dopamine-β-hydroxylase, DBH), rs4680 (catechol-O-methyltransferase, COMT), and rs1800497 (dopamine receptor D2-associated ANKK1 TAQ-1A).	0.000271442	2013	ANKK1	11	113400106	G	A
rs1800497	22881836	1312	COMT	umls:C0014544	BeFree	Stage 1 analysis included 290 patients with epilepsy and revealed a higher load of adverse psychotropic side effects of LEV in patients carrying genetic variants associated with decreased dopaminergic activity: rs1611115 (dopamine-β-hydroxylase, DBH), rs4680 (catechol-O-methyltransferase, COMT), and rs1800497 (dopamine receptor D2-associated ANKK1 TAQ-1A).	0.000271442	2013	ANKK1	11	113400106	G	A
rs1800629	22578659	3553	IL1B	umls:C0014544	BeFree	To understand the role of genes encoding pro-inflammatory cytokines in epilepsy, this study aimed to evaluate the polymorphisms of the promoter regions of IL-1β-511C>T (rs16944), TNF-α-308G>A (rs1800629) and IL-6-174G>C (rs1800795) genes and to look into the interaction between these genes in influencing seizure susceptibility, seizure frequency and response to therapy.	0.002442977	2012	TNF	6	31575254	G	A
rs1800629	22578659	3569	IL6	umls:C0014544	BeFree	To understand the role of genes encoding pro-inflammatory cytokines in epilepsy, this study aimed to evaluate the polymorphisms of the promoter regions of IL-1β-511C>T (rs16944), TNF-α-308G>A (rs1800629) and IL-6-174G>C (rs1800795) genes and to look into the interaction between these genes in influencing seizure susceptibility, seizure frequency and response to therapy.	0.001357209	2012	TNF	6	31575254	G	A
rs1800795	22578659	3553	IL1B	umls:C0014544	BeFree	To understand the role of genes encoding pro-inflammatory cytokines in epilepsy, this study aimed to evaluate the polymorphisms of the promoter regions of IL-1β-511C>T (rs16944), TNF-α-308G>A (rs1800629) and IL-6-174G>C (rs1800795) genes and to look into the interaction between these genes in influencing seizure susceptibility, seizure frequency and response to therapy.	0.002442977	2012	IL6;LOC541472	7	22727026	C	G
rs1800795	22578659	3569	IL6	umls:C0014544	BeFree	To understand the role of genes encoding pro-inflammatory cytokines in epilepsy, this study aimed to evaluate the polymorphisms of the promoter regions of IL-1β-511C>T (rs16944), TNF-α-308G>A (rs1800629) and IL-6-174G>C (rs1800795) genes and to look into the interaction between these genes in influencing seizure susceptibility, seizure frequency and response to therapy.	0.001357209	2012	IL6;LOC541472	7	22727026	C	G
rs1801545	18625963	3785	KCNQ2	umls:C0014544	BeFree	In KCNQ2, a silent single nucleotide polymorphism (rs1801545) was found overrepresented in both epilepsy samples (IGE, p = 0.004).	0.140030617	2008	KCNQ2	20	63414925	G	C,A
rs1805087	21543238	4548	MTR	umls:C0014544	BeFree	The purpose of the study was to determine the frequency of occurrence of polymorphisms of genes MTHFR (C677T), MTR (A2756G), and MTHFD1 (G1958A), as well as to analyze the concentration of homocysteine (Hcy), methionine (Met), asymmetric dimethylarginine (ADMA), and arginine (Arg) in epileptics treatment with antiepileptic drugs (AEDs), and controls.	0.002909916	2011	MTR	1	236885200	A	G
rs1805087	21543238	4524	MTHFR	umls:C0014544	BeFree	The purpose of the study was to determine the frequency of occurrence of polymorphisms of genes MTHFR (C677T), MTR (A2756G), and MTHFD1 (G1958A), as well as to analyze the concentration of homocysteine (Hcy), methionine (Met), asymmetric dimethylarginine (ADMA), and arginine (Arg) in epileptics treatment with antiepileptic drugs (AEDs), and controls.	0.022636753	2011	MTR	1	236885200	A	G
rs1939012	25087078	4317	MMP8	umls:C0014544	GWASCAT	Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies.	0.12	2014	MMP8	11	102724404	T	C
rs193929358	17259376	3767	KCNJ11	umls:C0014544	BeFree	Here we describe a patient with severe PNDM, which includes developmental delay and epilepsy, in addition to neonatal diabetes (developmental delay, epilepsy, and neonatal diabetes [DEND]), due to a G334D mutation in the Kir6.2 subunit of K(ATP) channel.	0.010344586	2007	KCNJ11	11	17387091	C	T
rs2032582	24213830	5243	ABCB1	umls:C0014544	BeFree	The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children.	0.194338987	2013	ABCB1	7	87531302	A	T,C
rs2071197	24384557	8856	NR1I2	umls:C0014544	BeFree	The common polymorphisms of nuclear receptors--a tentative pregnane X receptor (PXR)1B, hepatocyte nuclear factor 4α (HNF4α) rs2071197 (c.115+308G>A), and cytochrome P450 3A53 polymorphisms--were genotyped in 168 Japanese patients with epilepsy.	0.003181358	2014	HNF4A	20	44401795	G	A
rs2071197	24384557	1577	CYP3A5	umls:C0014544	BeFree	The common polymorphisms of nuclear receptors--a tentative pregnane X receptor (PXR)1B, hepatocyte nuclear factor 4α (HNF4α) rs2071197 (c.115+308G>A), and cytochrome P450 3A53 polymorphisms--were genotyped in 168 Japanese patients with epilepsy.	0.002909916	2014	HNF4A	20	44401795	G	A
rs2071197	24384557	3172	HNF4A	umls:C0014544	BeFree	The common polymorphisms of nuclear receptors--a tentative pregnane X receptor (PXR)1B, hepatocyte nuclear factor 4α (HNF4α) rs2071197 (c.115+308G>A), and cytochrome P450 3A53 polymorphisms--were genotyped in 168 Japanese patients with epilepsy.	0.000271442	2014	HNF4A	20	44401795	G	A
rs211037	22239287	5243	ABCB1	umls:C0014544	BeFree	Role of MDR1 C3435T and GABRG2 C588T gene polymorphisms in seizure occurrence and MDR1 effect on anti-epileptic drug (phenytoin) absorption.	0.194338987	2012	GABRG2	5	162101274	C	T
rs211037	24061200	2554	GABRA1	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.004810009	2014	GABRG2	5	162101274	C	T
rs211037	24061200	2559	GABRA6	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.000542884	2014	GABRG2	5	162101274	C	T
rs211037	23140995	2566	GABRG2	umls:C0014544	BeFree	GABRG2 rs211037 polymorphism and epilepsy: a systematic review and meta-analysis.	0.017806881	2013	GABRG2	5	162101274	C	T
rs211037	24061200	2566	GABRG2	umls:C0014544	BeFree	GABRG2, rs211037 is associated with epilepsy susceptibility, but not with antiepileptic drug resistance and febrile seizures.	0.017806881	2014	GABRG2	5	162101274	C	T
rs211037	24061200	2561	GABRB2	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.000814326	2014	GABRG2	5	162101274	C	T
rs2229944	24061200	2554	GABRA1	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.004810009	2014	GABRB2	5	161294312	G	A
rs2229944	24061200	2561	GABRB2	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.000814326	2014	GABRB2	5	161294312	G	A
rs2229944	24061200	2559	GABRA6	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.000542884	2014	GABRB2	5	161294312	G	A
rs2273697	25847339	1244	ABCC2	umls:C0014544	BeFree	The recessive model of MRP2 G1249A polymorphism decrease the risk of drug-resistant in Asian Epilepsy: a systematic review and meta-analysis.	0.009348576	2015	ABCC2	10	99804058	G	A
rs2273697	24624913	1244	ABCC2	umls:C0014544	BeFree	ABCC2 rs2273697 and rs3740066 polymorphisms and resistance to antiepileptic drugs in Asia Pacific epilepsy cohorts.	0.009348576	2015	ABCC2	10	99804058	G	A
rs2279020	24061200	2559	GABRA6	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.000542884	2014	GABRA1	5	161895883	G	A
rs2279020	24061200	2554	GABRA1	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.004810009	2014	GABRA1	5	161895883	G	A
rs2279020	24061200	2561	GABRB2	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.000814326	2014	GABRA1	5	161895883	G	A
rs2292096	22116939	23271	CAMSAP2	umls:C0014544	GAD	[Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese.]	0.122909916	2012	CAMSAP2	1	200857641	A	G
rs2292096	22116939	23271	CAMSAP2	umls:C0014544	GWASCAT	Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese.	0.122909916	2012	CAMSAP2	1	200857641	A	G
rs2304016	18784617	6326	SCN2A	umls:C0014544	GAD	[Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.]	0.143688845	2008	SCN2A	2	165311993	A	G
rs267608436	17993579	6792	CDKL5	umls:C0014544	BeFree	We screened the entire coding region of CDKL5 in 151 affected girls with a clinically heterogeneous phenotype ranging from encephalopathy with epilepsy to atypical Rett syndrome by denaturing high liquid performance chromatography and direct sequencing, and we identified three novel missense mutations located in catalytic domain (p.Ala40Val, p.Arg65Gln, p.Leu220Pro).	0.02005048	2008	CDKL5	X	18575402	G	A
rs267608511	17993579	6792	CDKL5	umls:C0014544	BeFree	We screened the entire coding region of CDKL5 in 151 affected girls with a clinically heterogeneous phenotype ranging from encephalopathy with epilepsy to atypical Rett syndrome by denaturing high liquid performance chromatography and direct sequencing, and we identified three novel missense mutations located in catalytic domain (p.Ala40Val, p.Arg65Gln, p.Leu220Pro).	0.02005048	2008	CDKL5	X	18588058	T	C
rs267608665	19428276	6792	CDKL5	umls:C0014544	BeFree	A novel p.Arg970X mutation in the last exon of the CDKL5 gene resulting in late-onset seizure disorder.	0.02005048	2010	RS1;CDKL5	X	18650520	C	T
rs281865071	15964197	1141	CHRNB2	umls:C0014544	BeFree	The CHRNB2 mutation I312M is associated with epilepsy and distinct memory deficits.	0.001085767	2005	CHRNB2	1	154571759	C	G
rs28934906	20231667	4204	MECP2	umls:C0014544	BeFree	MECP2 mutations most frequently associated with epilepsy were T158M (74%) and R106W (78%), and less frequently R255X and R306C (both 49%).	0.014168516	2010	MECP2	X	154031355	G	A
rs28934907	20231667	4204	MECP2	umls:C0014544	BeFree	MECP2 mutations most frequently associated with epilepsy were T158M (74%) and R106W (78%), and less frequently R255X and R306C (both 49%).	0.014168516	2010	MECP2	X	154032268	G	C,A
rs28935468	20231667	4204	MECP2	umls:C0014544	BeFree	MECP2 mutations most frequently associated with epilepsy were T158M (74%) and R106W (78%), and less frequently R255X and R306C (both 49%).	0.014168516	2010	MECP2	X	154030912	G	A
rs2920502	25595263	6854	SYN2	umls:C0014544	BeFree	Evidence has shown linkage disequilibrium between rs3755724 (-55C/T) of this gene with synapsin 2 (SYN2) rs3773364 and peroxisome proliferator-activated G receptor (PPARG) rs2920502 loci, which contribute to epilepsy in Caucasians.	0.003181358	2014	PPARG	3	12287696	G	C
rs3219151	24061200	2561	GABRB2	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.000814326	2014	GABRA6	5	161701908	C	T
rs3219151	24061200	2559	GABRA6	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.000542884	2014	GABRA6	5	161701908	C	T
rs3219151	24061200	2554	GABRA1	umls:C0014544	BeFree	We investigated the association of single-nucleotide polymorphisms in GABA(A) receptor subunit subtype genes namely; rs2279020 (GABRA1), rs3219151 (GABRA6), rs2229944 (GABRB2), and rs211037 (GABRG2) with predisposition to epilepsy and AED resistance.	0.004810009	2014	GABRA6	5	161701908	C	T
rs3740066	24624913	1244	ABCC2	umls:C0014544	BeFree	ABCC2 rs2273697 and rs3740066 polymorphisms and resistance to antiepileptic drugs in Asia Pacific epilepsy cohorts.	0.009348576	2015	ABCC2	10	99844450	C	T,G
rs3755724	25595263	6854	SYN2	umls:C0014544	BeFree	Evidence has shown linkage disequilibrium between rs3755724 (-55C/T) of this gene with synapsin 2 (SYN2) rs3773364 and peroxisome proliferator-activated G receptor (PPARG) rs2920502 loci, which contribute to epilepsy in Caucasians.	0.003181358	2014	SYN2;TIMP4	3	12159406	C	T
rs3773364	25595263	6854	SYN2	umls:C0014544	BeFree	Evidence has shown linkage disequilibrium between rs3755724 (-55C/T) of this gene with synapsin 2 (SYN2) rs3773364 and peroxisome proliferator-activated G receptor (PPARG) rs2920502 loci, which contribute to epilepsy in Caucasians.	0.003181358	2014	SYN2	3	12148468	A	G
rs3812718	24076350	6323	SCN1A	umls:C0014544	BeFree	SCN1A rs3812718 polymorphism and susceptibility to epilepsy with febrile seizures: a meta-analysis.	0.323466984	2013	SCN1A	2	166053034	C	T
rs3812718	25668517	6323	SCN1A	umls:C0014544	BeFree	RORA gene rs12912233 and rs880626 polymorphisms and their interaction with SCN1A rs3812718 in the risk of epilepsy: a case-control study in Malaysia.	0.323466984	2015	SCN1A	2	166053034	C	T
rs3812718	25668517	6095	RORA	umls:C0014544	BeFree	RORA gene rs12912233 and rs880626 polymorphisms and their interaction with SCN1A rs3812718 in the risk of epilepsy: a case-control study in Malaysia.	0.000271442	2015	SCN1A	2	166053034	C	T
rs3815823	23751308	9961	MVP	umls:C0014544	BeFree	We conclude that rs4788187, rs3815824, rs3815823 variants of the MVP gene are associated neither with predisposition for epilepsy nor with AED-resistance in the population that we have studied.	0.000542884	2013	MVP	16	29847228	G	A
rs3815824	23751308	9961	MVP	umls:C0014544	BeFree	We conclude that rs4788187, rs3815824, rs3815823 variants of the MVP gene are associated neither with predisposition for epilepsy nor with AED-resistance in the population that we have studied.	0.000542884	2013	MVP	16	29841539	C	T
rs386596107	22119635	6648	SOD2	umls:C0014544	BeFree	The association between the superoxide dismutase 2 (SOD2) Val16Ala polymorphism and the serum aminotransferase levels was retrospectively investigated in 207 valproic acid-treated patients with epilepsy.	0.000542884	2012	NA	NA	NA	NA	NA
rs386596107	25372290	6648	SOD2	umls:C0014544	BeFree	Our results showed that the SOD2 Val16Ala polymorphism has an impact on the relationship between VPA exposure and γ-GT elevation in patients with epilepsy.	0.000542884	2014	NA	NA	NA	NA	NA
rs386602118	21890420	627	BDNF	umls:C0014544	BeFree	The Val66Met polymorphism in the BDNF gene may be involved in the alteration of normal secretion of the mature peptide and may modulate the epileptic phenotype observed in some patients with FXS.	0.13062984	2011	NA	NA	NA	NA	NA
rs386833981	17607606	1203	CLN5	umls:C0014544	BeFree	We report two sibs harbouring a novel mutation (p.Tyr258Asp) in the CLN5 gene and displaying behaviour disturbances and mental deterioration, rather than epilepsy, as the dominant disease manifestation at onset.	0.000542884	2007	CLN5	13	77000517	T	G
rs387906783	20022885	3767	KCNJ11	umls:C0014544	BeFree	We report two novel mutations on the same haplotype (cis), F60Y and V64L, in the slide helix of Kir6.2 in a patient with neonatal diabetes, developmental delay and epilepsy.	0.010344586	2010	KCNJ11	11	17387913	A	T
rs397507444	15970629	4524	MTHFR	umls:C0014544	BeFree	Screening for C677T and A1298C MTHFR polymorphisms in patients with epilepsy and risk of hyperhomocysteinemia.	0.022636753	2004	MTHFR	1	11794407	T	G
rs397507444	24183735	4524	MTHFR	umls:C0014544	BeFree	The role of C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene (MTHFR) on the increase of plasma tHcy in patients with epilepsy taking AEDs is still controversial.	0.022636753	2013	MTHFR	1	11794407	T	G
rs39861	22949513	375449	MAST4	umls:C0014544	GWASCAT	Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32.	0.12	2012	MAST4	5	66856430	A	G
rs4680	22881836	1621	DBH	umls:C0014544	BeFree	Stage 1 analysis included 290 patients with epilepsy and revealed a higher load of adverse psychotropic side effects of LEV in patients carrying genetic variants associated with decreased dopaminergic activity: rs1611115 (dopamine-β-hydroxylase, DBH), rs4680 (catechol-O-methyltransferase, COMT), and rs1800497 (dopamine receptor D2-associated ANKK1 TAQ-1A).	0.000271442	2013	COMT;MIR4761	22	19963748	G	A
rs4680	22881836	1312	COMT	umls:C0014544	BeFree	Stage 1 analysis included 290 patients with epilepsy and revealed a higher load of adverse psychotropic side effects of LEV in patients carrying genetic variants associated with decreased dopaminergic activity: rs1611115 (dopamine-β-hydroxylase, DBH), rs4680 (catechol-O-methyltransferase, COMT), and rs1800497 (dopamine receptor D2-associated ANKK1 TAQ-1A).	0.000271442	2013	COMT;MIR4761	22	19963748	G	A
rs4788187	23751308	9961	MVP	umls:C0014544	BeFree	We conclude that rs4788187, rs3815824, rs3815823 variants of the MVP gene are associated neither with predisposition for epilepsy nor with AED-resistance in the population that we have studied.	0.000542884	2013	MVP	16	29834364	T	C
rs4828696	24236484	2555	GABRA2	umls:C0014544	BeFree	Further multivariate logistic regression and multifactor dimensionality reduction analyses of interactions between these genes showed that under adjustment of clinical factors, the epilepsy treatment outcomes were significantly associated with the genotype combinations of GABRA1 rs6883877, GABRA2 rs511310 and GABRA3 rs4828696 (p < 0.0001; adjusted r(2) = 0.149).	0.000271442	2014	GABRA3	X	152413524	T	C
rs4828696	24236484	2554	GABRA1	umls:C0014544	BeFree	Further multivariate logistic regression and multifactor dimensionality reduction analyses of interactions between these genes showed that under adjustment of clinical factors, the epilepsy treatment outcomes were significantly associated with the genotype combinations of GABRA1 rs6883877, GABRA2 rs511310 and GABRA3 rs4828696 (p < 0.0001; adjusted r(2) = 0.149).	0.004810009	2014	GABRA3	X	152413524	T	C
rs4828696	24236484	2556	GABRA3	umls:C0014544	BeFree	Further multivariate logistic regression and multifactor dimensionality reduction analyses of interactions between these genes showed that under adjustment of clinical factors, the epilepsy treatment outcomes were significantly associated with the genotype combinations of GABRA1 rs6883877, GABRA2 rs511310 and GABRA3 rs4828696 (p < 0.0001; adjusted r(2) = 0.149).	0.000271442	2014	GABRA3	X	152413524	T	C
rs4880	22119635	6648	SOD2	umls:C0014544	BeFree	The association between the superoxide dismutase 2 (SOD2) Val16Ala polymorphism and the serum aminotransferase levels was retrospectively investigated in 207 valproic acid-treated patients with epilepsy.	0.000542884	2012	SOD2	6	159692840	A	G
rs4880	25372290	6648	SOD2	umls:C0014544	BeFree	Our results showed that the SOD2 Val16Ala polymorphism has an impact on the relationship between VPA exposure and γ-GT elevation in patients with epilepsy.	0.000542884	2014	SOD2	6	159692840	A	G
rs4986790	20807077	7099	TLR4	umls:C0014544	BeFree	A total of 140 patients with NCC (82 symptomatic [ie, with active epilepsy] and 58 asymptomatic) and 150 healthy control subjects were examined for TLR4 Asp299Gly and Thr399Ile polymorphisms by means of polymerase chain reaction and restriction fragment-length polymorphism.	0.003181358	2010	TLR4	9	117713024	A	G
rs4986791	20807077	7099	TLR4	umls:C0014544	BeFree	A total of 140 patients with NCC (82 symptomatic [ie, with active epilepsy] and 58 asymptomatic) and 150 healthy control subjects were examined for TLR4 Asp299Gly and Thr399Ile polymorphisms by means of polymerase chain reaction and restriction fragment-length polymorphism.	0.003181358	2010	TLR4	9	117713324	C	T
rs511310	24236484	2554	GABRA1	umls:C0014544	BeFree	Further multivariate logistic regression and multifactor dimensionality reduction analyses of interactions between these genes showed that under adjustment of clinical factors, the epilepsy treatment outcomes were significantly associated with the genotype combinations of GABRA1 rs6883877, GABRA2 rs511310 and GABRA3 rs4828696 (p < 0.0001; adjusted r(2) = 0.149).	0.004810009	2014	NA	4	46237987	A	G
rs511310	24236484	2555	GABRA2	umls:C0014544	BeFree	Further multivariate logistic regression and multifactor dimensionality reduction analyses of interactions between these genes showed that under adjustment of clinical factors, the epilepsy treatment outcomes were significantly associated with the genotype combinations of GABRA1 rs6883877, GABRA2 rs511310 and GABRA3 rs4828696 (p < 0.0001; adjusted r(2) = 0.149).	0.000271442	2014	NA	4	46237987	A	G
rs511310	24236484	2556	GABRA3	umls:C0014544	BeFree	Further multivariate logistic regression and multifactor dimensionality reduction analyses of interactions between these genes showed that under adjustment of clinical factors, the epilepsy treatment outcomes were significantly associated with the genotype combinations of GABRA1 rs6883877, GABRA2 rs511310 and GABRA3 rs4828696 (p < 0.0001; adjusted r(2) = 0.149).	0.000271442	2014	NA	4	46237987	A	G
rs59007384	24786335	10452	TOMM40	umls:C0014544	BeFree	Compared with children carrying the GG allele, children with genotype GT or TT in a specific genetic variation (rs59007384 located in the nearby TOMM40 gene) had excess risk for worse fine motor function (Odds ratio (OR): 1.82; 95% Confidence interval (CI): 1.10-2.99; p = 0.019) and epilepsy (OR: 2.32; CI: 1.17-4.61; p = 0.016).	0.000271442	2014	TOMM40	19	44893408	G	T
rs61749721	20231667	4204	MECP2	umls:C0014544	BeFree	MECP2 mutations most frequently associated with epilepsy were T158M (74%) and R106W (78%), and less frequently R255X and R306C (both 49%).	0.014168516	2010	MECP2	X	154031065	G	A
rs635311	19605733	3497	IGHE	umls:C0014544	BeFree	The AE3-A867D allele in humans has been associated with the development of IGE (IGE), which accounts for approximately 30% of all epilepsies.	0.001357209	2009	SLC4A3	2	219637645	A	C,T
rs635311	19605733	6508	SLC4A3	umls:C0014544	BeFree	The AE3-A867D allele in humans has been associated with the development of IGE (IGE), which accounts for approximately 30% of all epilepsies.	0.002909916	2009	SLC4A3	2	219637645	A	C,T
rs63750231	15230697	5663	PSEN1	umls:C0014544	BeFree	CA1 hippocampal neuronal loss in familial Alzheimer's disease presenilin-1 E280A mutation is related to epilepsy.	0.000814326	2004	PSEN1	14	73198100	A	C,G
rs671	25313998	1991	ELANE	umls:C0014544	BeFree	The ALDH2 rs671 polymorphism affects post-stroke epilepsy susceptibility and plasma 4-HNE levels.	0.000271442	2014	ALDH2	12	111803962	G	A
rs671	25313998	217	ALDH2	umls:C0014544	BeFree	The ALDH2 rs671 polymorphism affects post-stroke epilepsy susceptibility and plasma 4-HNE levels.	0.000271442	2014	ALDH2	12	111803962	G	A
rs6732655	25087078	6323	SCN1A	umls:C0014544	GWASCAT	Meta-analysis of the all-epilepsy cohort identified loci at 2q24.3 (p=8·71 × 10(-10)), implicating SCN1A, and at 4p15.1 (p=5·44 × 10(-9)), harbouring PCDH7, which encodes a protocadherin molecule not previously implicated in epilepsy.	0.323466984	2014	SCN1A	2	166038556	A	T
rs6883877	24236484	2554	GABRA1	umls:C0014544	BeFree	Further multivariate logistic regression and multifactor dimensionality reduction analyses of interactions between these genes showed that under adjustment of clinical factors, the epilepsy treatment outcomes were significantly associated with the genotype combinations of GABRA1 rs6883877, GABRA2 rs511310 and GABRA3 rs4828696 (p < 0.0001; adjusted r(2) = 0.149).	0.004810009	2014	GABRA1	5	161851332	C	T
rs6883877	24236484	2556	GABRA3	umls:C0014544	BeFree	Further multivariate logistic regression and multifactor dimensionality reduction analyses of interactions between these genes showed that under adjustment of clinical factors, the epilepsy treatment outcomes were significantly associated with the genotype combinations of GABRA1 rs6883877, GABRA2 rs511310 and GABRA3 rs4828696 (p < 0.0001; adjusted r(2) = 0.149).	0.000271442	2014	GABRA1	5	161851332	C	T
rs6883877	24236484	2555	GABRA2	umls:C0014544	BeFree	Further multivariate logistic regression and multifactor dimensionality reduction analyses of interactions between these genes showed that under adjustment of clinical factors, the epilepsy treatment outcomes were significantly associated with the genotype combinations of GABRA1 rs6883877, GABRA2 rs511310 and GABRA3 rs4828696 (p < 0.0001; adjusted r(2) = 0.149).	0.000271442	2014	GABRA1	5	161851332	C	T
rs72700966	23962720	5789	PTPRD	umls:C0014544	GWASCAT	A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy.	0.12	2014	PTPRD	9	10505224	C	T
rs79761183	25489633	114327	EFHC1	umls:C0014544	BeFree	Public databases also show that the EFHC1 P77T-R221H JME haplotype is present in unphenotyped West African ancestry populations, and we show that it can be found at appreciable frequency in healthy individuals with no family history of epilepsy.	0.004895885	2014	EFHC1	6	52452776	G	A
rs80356616	16087682	3767	KCNJ11	umls:C0014544	BeFree	Recent studies have shown that heterozygous mutations in KCNJ11, which encodes Kir6.2, the pore-forming subunit of the ATP-sensitive potassium (K(ATP)) channel, cause permanent neonatal diabetes either alone (R201C, R201H) or in association with developmental delay, muscle weakness and epilepsy (V59G,V59M).	0.010344586	2005	KCNJ11	11	17387917	C	T
rs80356617	16087682	3767	KCNJ11	umls:C0014544	BeFree	Recent studies have shown that heterozygous mutations in KCNJ11, which encodes Kir6.2, the pore-forming subunit of the ATP-sensitive potassium (K(ATP)) channel, cause permanent neonatal diabetes either alone (R201C, R201H) or in association with developmental delay, muscle weakness and epilepsy (V59G,V59M).	0.010344586	2005	KCNJ11	11	17387916	A	C
rs80356624	16087682	3767	KCNJ11	umls:C0014544	BeFree	Recent studies have shown that heterozygous mutations in KCNJ11, which encodes Kir6.2, the pore-forming subunit of the ATP-sensitive potassium (K(ATP)) channel, cause permanent neonatal diabetes either alone (R201C, R201H) or in association with developmental delay, muscle weakness and epilepsy (V59G,V59M).	0.010344586	2005	KCNJ11	11	17387490	C	T,A
rs880626	25668517	6323	SCN1A	umls:C0014544	BeFree	RORA gene rs12912233 and rs880626 polymorphisms and their interaction with SCN1A rs3812718 in the risk of epilepsy: a case-control study in Malaysia.	0.323466984	2015	RORA	15	60691230	G	A
rs880626	25668517	6095	RORA	umls:C0014544	BeFree	RORA gene rs12912233 and rs880626 polymorphisms and their interaction with SCN1A rs3812718 in the risk of epilepsy: a case-control study in Malaysia.	0.000271442	2015	RORA	15	60691230	G	A

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:207)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	3275149	rs12748963	C	T	rs12748963	22116939	1.74E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
1	4748305	rs1076944	G	T	rs1076944	22116939	2.04E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
1	34750936	rs771390	T	C	rs771390	22949513	6.00E-07	All GGE	1.22	[1.12-1.32]	702 European ancestry GAE cases; 586 European ancestry JME cases; 239 European ancestry other GGE cases; 2,461 European ancestry controls	European(3988)	ALL(3988)	EUR(3988)	ALL(3988)	Epilepsy (generalized)	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	rs771390-C	Research Support, Non-U.S. Gov't	C	NA
1	77751193	rs10747353	A	C	rs10747353	22116939	3.49E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
1	77768778	rs10493603	A	G	rs10493603	22116939	3.26E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
1	77784762	rs12751884	A	G	rs12751884	22116939	3.11E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
1	77815566	rs1010196	C	T	rs1010196	22116939	4.34E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
1	96025546	rs1396626	G	A	rs1396626	22116939	3.32E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
1	97316690	rs11584143	G	A	rs11584143	22116939	1.22E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
1	115877522	rs10858075	C	T	rs10858075	22116939	3.37E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
1	146969411	rs12406844	C	T	rs12406844	22116939	2.98E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
1	169405517	rs12092506	A	G	rs12092506	22116939	2.13E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
1	186870072	rs12720541	G	T	rs12720541	22949513	9.00E-06	GAE	1.21	[1.10-1.35]	702 European ancestry GAE cases; 586 European ancestry JME cases; 239 European ancestry other GGE cases; 2,461 European ancestry controls	European(3988)	ALL(3988)	EUR(3988)	ALL(3988)	Epilepsy (generalized)	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	rs12720541-T	Research Support, Non-U.S. Gov't	G	PLA2G4A
1	200703541	rs6660197	C	T	rs6660197	22116939	6.78E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
1	200811765	rs12742404	A	G	rs12742404	22116939	6.39E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
1	200826769	rs2292096	A	G	rs2292096	22116939	1.00E-08	NA	1.59	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
1	239970097	rs12059546	A	G	rs12059546	22949513	4.00E-08	JME	1.42	[1.26-1.61]	702 European ancestry GAE cases; 586 European ancestry JME cases; 239 European ancestry other GGE cases; 2,461 European ancestry controls	European(3988)	ALL(3988)	EUR(3988)	ALL(3988)	Epilepsy (generalized)	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	rs12059546-G	Research Support, Non-U.S. Gov't	A	CHRM3
2	15106804	rs4670047	C	T	rs4670047	22116939	6.02E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	15110323	rs7587023	C	T	rs7587023	22116939	4.37E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	57934055	rs13026414	C	T	rs13026414	22949513	2.00E-09	All GGE	1.23	[1.15-1.32]	702 European ancestry GAE cases; 586 European ancestry JME cases; 239 European ancestry other GGE cases; 2,461 European ancestry controls	European(3988)	ALL(3988)	EUR(3988)	ALL(3988)	Epilepsy (generalized)	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	rs13026414-C	Research Support, Non-U.S. Gov't	C	NA
2	58094873	rs2717068	A	C	rs2717068	22949513	4.00E-07	GAE	1.27	[1.16-1.40]	702 European ancestry GAE cases; 586 European ancestry JME cases; 239 European ancestry other GGE cases; 2,461 European ancestry controls	European(3988)	ALL(3988)	EUR(3988)	ALL(3988)	Epilepsy (generalized)	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	rs2717068-T	Research Support, Non-U.S. Gov't	G	NA
2	67952811	rs4671197	T	C	rs4671197	22116939	2.96E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	78117502	rs10865432	C	A	rs10865432	22116939	1.93E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	78120305	rs1897616	C	T	rs1897616	22116939	3.68E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	78124090	rs10172925	G	A	rs10172925	22116939	1.47E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	78133560	rs7602889	T	C	rs7602889	22116939	1.30E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	78139549	rs4853352	G	A	rs4853352	22116939	5.50E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	78144479	rs4853355	G	A	rs4853355	22116939	3.88E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	78145340	rs1433197	T	C	rs1433197	22116939	6.06E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	78170534	rs1368502	G	A	rs1368502	22116939	2.15E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	78199268	rs1074192	C	T	rs1074192	22116939	6.97E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	78214766	rs1609077	T	C	rs1609077	22116939	6.34E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	78221253	rs2163873	T	G	rs2163873	22116939	8.01E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	78263883	rs1527194	T	C	rs1527194	22116939	7.08E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	78302215	rs2164851	G	A	rs2164851	22116939	1.49E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	78311781	rs1437985	T	C	rs1437985	22116939	3.57E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	78314039	rs6547183	T	C	rs6547183	22116939	3.59E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	78332806	rs10173591	C	T	rs10173591	22116939	4.93E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	78341245	rs1370637	C	A	rs1370637	22116939	5.57E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	86683642	rs2030259	A	G	rs2030259	22116939	4.14E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	86720841	rs2367575	C	T	rs2367575	22116939	3.19E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	145359909	rs10496964	C	T	rs10496964	22949513	9.00E-09	GAE	1.47	[1.28-1.67]	702 European ancestry GAE cases; 586 European ancestry JME cases; 239 European ancestry other GGE cases; 2,461 European ancestry controls	European(3988)	ALL(3988)	EUR(3988)	ALL(3988)	Epilepsy (generalized)	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	rs10496964-C	Research Support, Non-U.S. Gov't	C	NA
2	154745009	rs16834756	A	G	rs16834756	22116939	3.68E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	166943277	rs11890028	T	G	rs11890028	22949513	4.00E-06	All GGE	1.18	[1.09-1.27]	702 European ancestry GAE cases; 586 European ancestry JME cases; 239 European ancestry other GGE cases; 2,461 European ancestry controls	European(3988)	ALL(3988)	EUR(3988)	ALL(3988)	Epilepsy (generalized)	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	rs11890028-T	Research Support, Non-U.S. Gov't	G	SCN1A
2	212350245	rs13021324	T	C	rs13021324	22116939	1.59E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	212351667	rs9941626	T	G	rs9941626	22116939	1.23E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	223567016	rs951997	A	G	rs951997	22116939	4.53E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	237531788	rs7588302	T	C	rs7588302	22116939	1.78E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	21686466	rs1387822	G	A	rs1387822	22116939	2.51E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
3	21701712	rs1320292	A	G	rs1320292	22116939	1.82E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	21719246	rs1490157	C	T	rs1490157	22116939	2.36E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	31851726	rs6773772	T	C	rs6773772	22116939	3.41E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	40267321	rs2679822	T	C	rs2679822	22116939	6.76E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	40273500	rs6599081	A	G	rs6599081	22116939	1.29E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	40275655	rs2371136	C	T	rs2371136	22116939	1.29E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	106928929	rs11915523	A	G	rs11915523	22116939	1.36E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
3	115522560	rs1062118	A	G	rs1062118	22116939	2.96E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	171292911	rs387048	C	A	rs387048	22116939	7.26E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	171301434	rs626270	T	C	rs626270	22116939	1.62E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	171304058	rs372623	C	T	rs372623	22116939	6.40E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	183425850	rs7612556	A	G	rs7612556	22116939	4.97E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	183455153	rs262977	A	G	rs262977	22116939	2.72E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	183476685	rs262993	G	A	rs262993	22116939	4.62E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	183517999	rs263044	A	G	rs263044	22116939	3.52E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	183527618	rs263025	T	C	rs263025	22116939	4.76E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
3	192223737	rs4687336	G	A	rs4687336	22116939	7.06E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
4	27298305	rs6821695	T	C	rs6821695	22116939	5.23E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
4	55455944	rs17826780	C	T	rs17826780	22116939	4.31E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
4	77763998	rs10518159	C	T	rs10518159	22116939	9.32E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
4	78193913	rs10518170	A	G	rs10518170	22116939	1.12E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
4	127213903	rs10011584	T	G	rs10011584	22116939	7.03E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
4	150457508	rs1394028	C	T	rs1394028	22116939	5.46E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
4	150483241	rs2654798	A	G	rs2654798	22116939	5.20E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
4	150520884	rs2654831	T	G	rs2654831	22116939	3.93E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
4	150725212	rs10030601	T	C	rs10030601	22949513	1.00E-06	GAE	1.58	[1.29-1.93]	702 European ancestry GAE cases; 586 European ancestry JME cases; 239 European ancestry other GGE cases; 2,461 European ancestry controls	European(3988)	ALL(3988)	EUR(3988)	ALL(3988)	Epilepsy (generalized)	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	rs10030601-C	Research Support, Non-U.S. Gov't	C	LOC285423
4	165404456	rs4691122	T	G	rs4691122	22116939	4.58E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
4	170146632	rs1876398	G	A	rs1876398	22116939	2.57E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
4	170166749	rs1876396	C	T	rs1876396	22116939	1.99E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
4	170203848	rs13112591	A	C	rs13112591	22116939	1.33E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
4	171634933	rs7663379	T	C	rs7663379	22116939	5.47E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
5	28585628	rs4478333	G	A	rs4478333	22116939	4.09E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	35668036	rs2172754	A	G	rs2172754	22116939	1.89E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G,A
5	35677385	rs6872795	A	G	rs6872795	22116939	1.32E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	41302815	rs320614	G	A	rs320614	22116939	4.24E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	66152258	rs39861	A	G	rs39861	22949513	3.00E-07	JME	1.26	[1.13-1.41]	702 European ancestry GAE cases; 586 European ancestry JME cases; 239 European ancestry other GGE cases; 2,461 European ancestry controls	European(3988)	ALL(3988)	EUR(3988)	ALL(3988)	Epilepsy (generalized)	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	rs39861-C	Research Support, Non-U.S. Gov't	T	MAST4
5	104490887	rs10043572	C	T	rs10043572	22116939	4.10E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
5	120369453	rs17147260	A	C	rs17147260	22116939	1.49E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	133023122	rs10751462	A	G	rs10751462	22116939	1.43E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	133037459	rs720770	C	T	rs720770	22116939	1.81E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	133047775	rs6596147	T	C	rs6596147	22116939	2.97E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
5	142529960	rs258799	T	G	rs258799	22116939	1.90E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
5	164148566	rs1293554	G	A	rs1293554	22116939	2.14E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	166887629	rs1864975	T	C	rs1864975	22116939	3.39E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	7267582	rs2842363	A	G	rs2842363	22116939	1.75E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	22365762	rs1205918	A	G	rs1205918	22116939	5.40E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	80564519	rs9341799	T	C	rs9341799	22116939	2.08E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	80564836	rs346291	C	T	rs346291	22116939	2.51E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
6	93942185	rs1486756	A	G	rs1486756	22116939	1.85E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	101957291	rs7747072	T	C	rs7747072	22116939	1.56E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	101964914	rs9390754	A	G	rs9390754	22116939	5.46E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	102307069	rs9390790	G	A	rs9390790	22116939	6.00E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	102327303	rs4840200	T	C	rs4840200	22116939	1.42E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	133350936	rs3012465	A	G	rs3012465	22116939	1.57E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	133768525	rs17062561	A	G	rs17062561	22116939	4.31E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	133803682	rs6905892	C	T	rs6905892	22116939	8.98E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
7	5618237	rs2693946	C	T	rs2693946	22116939	9.12E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
7	24468539	rs12533743	T	C	rs12533743	22116939	3.64E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
7	49362161	rs1529590	C	T	rs1529590	22116939	2.20E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
7	97857675	rs2270604	T	C	rs2270604	22116939	4.17E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
7	97880226	rs954050	T	C	rs954050	22116939	1.18E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
7	97965016	rs3801263	A	G	rs3801263	22116939	3.02E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T,C
7	97972946	rs6945554	T	C	rs6945554	22116939	3.02E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
7	97975542	rs6961129	T	G	rs6961129	22116939	2.91E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
7	120155270	rs702416	C	T	rs702416	22116939	2.61E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
7	120156307	rs802333	T	C	rs802333	22116939	5.12E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
7	120169316	rs802372	A	G	rs802372	22116939	4.16E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
7	157700614	rs6944306	C	T	rs6944306	22116939	7.59E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
7	157734314	rs920023	A	G	rs920023	22116939	4.02E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
7	157735966	rs12670619	G	T	rs12670619	22116939	6.76E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
7	157736936	rs10249811	T	G	rs10249811	22116939	2.32E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
7	157743779	rs2164217	C	T	rs2164217	22116939	3.56E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
8	53031607	rs1346159	G	A	rs1346159	22116939	1.61E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G,A
8	53393301	rs2613258	C	A	rs2613258	22116939	6.85E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	59254904	rs7820691	T	C	rs7820691	22116939	1.93E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
8	66690822	rs974149	A	G	rs974149	22116939	3.02E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	66753261	rs6472225	C	T	rs6472225	22116939	7.09E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
8	92970153	rs4500123	A	G	rs4500123	22116939	1.39E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
8	129314766	rs976226	G	A	rs976226	22116939	3.00E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
8	132531794	rs273413	G	A	rs273413	22116939	7.24E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C,T
8	139379964	rs340707	T	C	rs340707	22116939	4.05E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
9	2640805	rs10967306	G	A	rs10967306	22116939	3.94E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
9	20219315	rs2034875	G	A	rs2034875	22116939	6.64E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
9	26117767	rs16910176	T	C	rs16910176	22116939	1.87E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
9	36154678	rs10814339	A	C	rs10814339	22116939	3.47E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
9	89327192	rs4878007	T	C	rs4878007	22116939	6.54E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
9	110280496	rs7041758	C	T	rs7041758	22116939	3.14E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
9	110418574	rs7849612	G	A	rs7849612	22116939	8.36E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
9	117120680	rs7866925	C	T	rs7866925	22116939	5.01E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
9	120031365	rs4837062	G	A	rs4837062	22116939	1.31E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
9	120043171	rs7026789	T	C	rs7026789	22116939	1.35E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
9	131953598	rs10760593	C	T	rs10760593	22116939	2.20E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
10	56411659	rs1414686	T	C	rs1414686	22116939	3.14E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
10	57578424	rs4935610	G	T	rs4935610	22116939	2.14E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
10	67653901	rs1942006	C	T	rs1942006	22116939	4.07E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
10	127738918	rs1710278	G	A	rs1710278	22116939	5.49E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
10	127744829	rs1710293	A	C	rs1710293	22116939	1.67E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
10	127755544	rs1278280	T	G	rs1278280	22116939	6.67E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
11	4953462	rs840716	G	T	rs840716	22116939	2.66E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
11	29897097	rs10501120	G	A	rs10501120	22116939	7.46E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
11	29938269	rs12222280	T	C	rs12222280	22116939	1.12E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
11	40276725	rs1037412	A	G	rs1037412	22116939	1.01E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
11	85526151	rs11607789	C	T	rs11607789	22116939	4.08E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
11	105503658	rs4754133	T	C	rs4754133	22116939	5.29E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
11	105588070	rs12808612	A	G	rs12808612	22116939	9.92E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
11	118793613	rs11217091	T	C	rs11217091	22116939	4.89E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
12	3374675	rs7296705	T	C	rs7296705	22116939	6.20E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
12	32378417	rs792853	G	A	rs792853	22116939	1.50E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
12	40697434	rs10784498	G	A	rs10784498	22116939	4.37E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
12	40768582	rs4768239	G	A	rs4768239	22116939	1.30E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
12	40792224	rs11564172	C	A	rs11564172	22116939	7.98E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
12	98208150	rs11109229	G	T	rs11109229	22116939	4.30E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
12	109432616	rs1865147	G	T	rs1865147	22116939	8.52E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
12	125778841	rs12146745	G	T	rs12146745	22116939	8.15E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	31958011	rs1571029	G	A	rs1571029	22116939	1.74E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	51588003	rs9526715	C	T	rs9526715	22116939	4.28E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	85528032	rs4911044	T	G	rs4911044	22116939	3.14E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	85588545	rs1354033	T	C	rs1354033	22116939	1.12E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	85605946	rs2485241	T	C	rs2485241	22116939	1.07E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	85609277	rs2485247	T	C	rs2485247	22116939	3.97E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
14	44130700	rs4900643	G	T	rs4900643	22116939	1.94E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
14	97331618	rs10135704	T	C	rs10135704	22116939	9.51E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
15	25063397	rs17114774	G	A	rs17114774	22116939	1.11E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
15	25064483	rs7171320	T	C	rs7171320	22116939	1.20E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
15	55125380	rs8025011	G	T	rs8025011	22116939	1.47E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
15	58992591	rs11853043	T	C	rs11853043	22116939	1.00E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
15	60983429	rs880626	G	A	rs880626	22116939	1.51E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
15	95473145	rs4281667	T	G	rs4281667	22116939	1.62E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
15	95479659	rs8037155	T	G	rs8037155	22116939	2.35E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
16	4103871	rs2601828	T	C	rs2601828	22116939	1.04E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
16	23959420	rs1989647	G	A	rs1989647	22116939	8.89E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
16	49997941	rs6500271	G	T	rs6500271	22116939	1.48E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
16	65170890	rs3890768	C	A	rs3890768	22116939	2.38E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
16	84448418	rs17741422	T	C	rs17741422	22116939	3.31E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
17	40219433	rs1076188	T	G	rs1076188	22116939	3.61E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
17	40224118	rs4796768	C	T	rs4796768	22116939	1.21E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
17	46123004	rs72823592	G	A	rs72823592	22949513	9.00E-09	All GGE	1.3	[1.20-1.41]	702 European ancestry GAE cases; 586 European ancestry JME cases; 239 European ancestry other GGE cases; 2,461 European ancestry controls	European(3988)	ALL(3988)	EUR(3988)	ALL(3988)	Epilepsy (generalized)	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	rs72823592-G	Research Support, Non-U.S. Gov't	G	NA
17	48195818	rs531650995	CACAG	C	rs739500	22116939	2.27E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
17	48195818	rs739500	C	T	rs739500	22116939	2.27E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
18	196829	rs655781	G	A	rs655781	22116939	1.56E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
18	204232	rs585578	G	A	rs585578	22116939	1.40E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
18	218695	rs481077	T	C	rs481077	22116939	1.82E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
18	220658	rs672856	G	A	rs672856	22116939	1.57E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
18	250047	rs577454	T	C	rs577454	22116939	1.76E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
18	286971	rs620837	C	A	rs620837	22116939	7.83E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
18	287648	rs16941940	T	G	rs16941940	22116939	7.06E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
18	322183	rs554821	G	A	rs554821	22116939	2.62E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
18	322522	rs621636	C	T	rs621636	22116939	2.59E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
18	22714149	rs7228750	G	A	rs7228750	22116939	3.53E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
19	57109821	rs10420820	C	T	rs10420820	22116939	2.19E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
19	57113178	rs3752183	C	T	rs3752183	22116939	1.60E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
20	6700202	rs6054486	T	G	rs6054486	22116939	9.16E-06	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
21	18863967	rs2824332	C	T	rs2824332	22116939	1.22E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
21	18900044	rs2824335	C	A	rs2824335	22116939	4.30E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
21	20124969	rs1573443	C	T	rs1573443	22116939	2.06E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
21	20126875	rs11700947	C	T	rs11700947	22116939	1.13E-04	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
21	31196773	rs9983495	G	T	rs9983495	22116939	5.49E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
21	41743639	rs1980406	T	C	rs1980406	22116939	1.12E-05	NA	NA	NA	504 Han Chinese cases; 2,947 Han Chinese controls	Han Chinese(3451)	ALL(3451)	ASN(3451)	ALL(3451)	Epilepsy	HPOID:0001250	Seizures	DOID:1826	epilepsy syndrome	D004827	Epilepsy	EFOID:0000474	epilepsy	Epilepsy	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:50)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0014544	amitriptyline	D000639	50-48-6	epilepsy	MESH:D004827	marker/mechanism	5823053
C0014544	amphetamine	D000661	300-62-9	epilepsy	MESH:D004827	marker/mechanism	8765941
C0014544	amphetamine	D000661	300-62-9	epilepsy	MESH:D004827	therapeutic	7715822
C0014544	ampicillin	D000667	69-53-4	epilepsy	MESH:D004827	marker/mechanism	8487076
C0014544	atropine	D001285	51-55-8	epilepsy	MESH:D004827	therapeutic	4058572
C0014544	busulfan	D002066	55-98-1	epilepsy	MESH:D004827	marker/mechanism	2041395
C0014544	carbachol	D002217	-	epilepsy	MESH:D004827	marker/mechanism	4058572
C0014544	carbamazepine	D002220	298-46-4	epilepsy	MESH:D004827	therapeutic	10371552
C0014544	chloramphenicol	D002701	56-75-7	epilepsy	MESH:D004827	marker/mechanism	8487076
C0014544	cimetidine	D002927	51481-61-9	epilepsy	MESH:D004827	marker/mechanism	6489391
C0014544	ciprofloxacin	D002939	85721-33-1	epilepsy	MESH:D004827	marker/mechanism	8487076
C0014544	citalopram	D015283	59729-33-8	epilepsy	MESH:D004827	therapeutic	20707986
C0014544	clonidine	D003000	4205-90-7	epilepsy	MESH:D004827	marker/mechanism	15792900
C0014544	clozapine	D003024	5786-21-0	epilepsy	MESH:D004827	marker/mechanism	1480676
C0014544	clozapine	D003024	5786-21-0	epilepsy	MESH:D004827	therapeutic	3751418
C0014544	dronabinol	D013759	-	epilepsy	MESH:D004827	therapeutic	821787
C0014544	cisplatin	D002945	15663-27-1	epilepsy	MESH:D004827	marker/mechanism	15354722
C0014544	enoxacin	D015365	74011-58-8	epilepsy	MESH:D004827	marker/mechanism	9010832
C0014544	erythromycin	D004917	114-07-8	epilepsy	MESH:D004827	marker/mechanism	8487076
C0014544	ethosuximide	D005013	77-67-8	epilepsy	MESH:D004827	therapeutic	812426
C0014544	felbamate	C047360	25451-15-4	epilepsy	MESH:D004827	therapeutic	7705426
C0014544	fluoxetine	D005473	54910-89-3	epilepsy	MESH:D004827	therapeutic	12632110
C0014544	fluvoxamine	D016666	54739-18-3	epilepsy	MESH:D004827	marker/mechanism	1958958
C0014544	folic acid	D005492	59-30-3	epilepsy	MESH:D004827	marker/mechanism	1115018
C0014544	gabapentin	C040029	60142-96-3	epilepsy	MESH:D004827	therapeutic	16675199
C0014544	griseofulvin	D006118	126-07-8	epilepsy	MESH:D004827	marker/mechanism	595848
C0014544	haloperidol	D006220	52-86-8	epilepsy	MESH:D004827	marker/mechanism	3751418
C0014544	metaraminol	D008680	54-49-9	epilepsy	MESH:D004827	marker/mechanism	2524805
C0014544	ifosfamide	D007069	3778-73-2	epilepsy	MESH:D004827	marker/mechanism	15354722
C0014544	imipramine	D007099	50-49-7	epilepsy	MESH:D004827	marker/mechanism	5823053
C0014544	lamotrigine	C047781	84057-84-1	epilepsy	MESH:D004827	therapeutic	10948577
C0014544	lidocaine	D008012	137-58-6	epilepsy	MESH:D004827	marker/mechanism	9768791
C0014544	mephenytoin	D008617	1950/12/4	epilepsy	MESH:D004827	therapeutic	1001284
C0014544	methohexital	D008723	18652-93-2	epilepsy	MESH:D004827	marker/mechanism	9701374
C0014544	methotrexate	D008727	1959/5/2	epilepsy	MESH:D004827	marker/mechanism	11019787
C0014544	morphine	D009020	57-27-2	epilepsy	MESH:D004827	marker/mechanism	1331416
C0014544	norepinephrine	D009638	51-41-2	epilepsy	MESH:D004827	therapeutic	821787
C0014544	pefloxacin	D015366	70458-92-3	epilepsy	MESH:D004827	marker/mechanism	2503281
C0014544	pentobarbital	D010424	76-74-4	epilepsy	MESH:D004827	therapeutic	7705426
C0014544	phenytoin	D010672	57-41-0	epilepsy	MESH:D004827	therapeutic	10219285
C0014544	picrotoxin	D010852	124-87-8	epilepsy	MESH:D004827	marker/mechanism	1922924
C0014544	pilocarpine	D010862	92-13-7	epilepsy	MESH:D004827	marker/mechanism	10401644
C0014544	pregabalin	D000069583	-	epilepsy	MESH:D004827	therapeutic	25290014
C0014544	protriptyline	D011530	438-60-8	epilepsy	MESH:D004827	marker/mechanism	5823053
C0014544	thalidomide	D013792	50-35-1	epilepsy	MESH:D004827	marker/mechanism	1278626
C0014544	topiramate	C052342	97240-79-4	epilepsy	MESH:D004827	therapeutic	12042105
C0014544	trimethadione	D014293	127-48-0	epilepsy	MESH:D004827	therapeutic	413897
C0014544	valproic acid	D014635	99-66-1	epilepsy	MESH:D004827	marker/mechanism	10846716
C0014544	valproic acid	D014635	99-66-1	epilepsy	MESH:D004827	therapeutic	10371552
C0014544	vigabatrin	D020888	60643-86-9	epilepsy	MESH:D004827	therapeutic	10219272

FDA approved drug and dosage information(Total Drugs:29)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D004827	neurontin	gabapentin	100MG	CAPSULE;ORAL	Prescription	AB	Yes	No
MESH:D004827	neurontin	gabapentin	600MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D004827	neurontin	gabapentin	250MG/5ML	SOLUTION;ORAL	Prescription	AA	Yes	Yes
MESH:D004827	neurontin	gabapentin	0	SOLUTION; ORAL	Prescription	None	No	No
MESH:D004827	neurontin	gabapentin	600MG	TABLET; ORAL	Prescription	None	No	No
MESH:D004827	neurontin	gabapentin	800MG	CAPSULE; ORAL	Prescription	None	No	No
MESH:D004827	neurontin	gabapentin	250MG/5ML	SOLUTION; ORAL	Prescription	None	No	No
MESH:D004827	busulfex	busulfan	6MG/ML	INJECTABLE;INJECTION	Prescription	AP	Yes	Yes
MESH:D004827	lamictal	lamotrigine	100MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D004827	lamictal	lamotrigine	100MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D004827	lamictal	lamotrigine	100MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D004827	lamictal xr	lamotrigine	25MG	TABLET, EXTENDED RELEASE;ORAL	Prescription	AB	Yes	No
MESH:D004827	lamictal xr	lamotrigine	25MG	TABLET, EXTENDED RELEASE;ORAL	Prescription	AB	Yes	No
MESH:D004827	lamictal xr	lamotrigine	25MG	TABLET, EXTENDED RELEASE;ORAL	Prescription	AB	Yes	No
MESH:D004827	cipro	ciprofloxacin	400MG/40ML (10MG/ML)	INJECTABLE;INJECTION	Discontinued	None	Yes	No
MESH:D004827	cipro	ciprofloxacin	250MG/5ML	FOR SUSPENSION;ORAL	Prescription	AB	Yes	No
MESH:D004827	topamax	topiramate	100MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D004827	topamax	topiramate	15MG	CAPSULE;ORAL	Prescription	AB	Yes	No
MESH:D004827	topamax	topiramate	100MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D004827	topamax	topiramate	15MG	CAPSULE;ORAL	Prescription	AB	Yes	No
MESH:D004827	topamax	topiramate	100MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D004827	topamax	topiramate	15MG	CAPSULE;ORAL	Prescription	AB	Yes	No
MESH:D004827	topamax	topiramate	100MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D004827	topamax	topiramate	15MG	CAPSULE;ORAL	Prescription	AB	Yes	No
MESH:D004827	sabril	vigabatrin	500MG	TABLET;ORAL	Prescription	None	Yes	Yes
MESH:D004827	sabril	vigabatrin	500MG/PACKET	FOR SOLUTION;ORAL	Prescription	AA	Yes	Yes
MESH:D004827	lyrica	pregabalin	25MG	CAPSULE;ORAL	Prescription	None	Yes	No
MESH:D004827	lyrica	pregabalin	25MG	CAPSULE; ORAL	Prescription	None	No	No
MESH:D004827	lyrica	pregabalin	25MG	CAPSULE; ORAL	Prescription	None	No	No

FDA labeling changes(Total Drugs:29)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D004827	12/10/2000	neurontin	gabapentin	Adjunctive therapy in the treatment of partial seizures	Safety and effectiveness established down to 3 years Neuropsychiatric AE's identified in 3-12 year olds Oral clearance normalized per body weight increased in children	Labeling	B	-	-	-	Parke-Davis	2/2/2000	FALSE'
MESH:D004827	12/10/2000	neurontin	gabapentin	Adjunctive therapy in the treatment of partial seizures	Safety and effectiveness established down to 3 years Neuropsychiatric AE's identified in 3-12 year olds Oral clearance normalized per body weight increased in children	Labeling	B	-	-	-	Parke-Davis	2/2/2000	FALSE'
MESH:D004827	12/10/2000	neurontin	gabapentin	Adjunctive therapy in the treatment of partial seizures	Safety and effectiveness established down to 3 years Neuropsychiatric AE's identified in 3-12 year olds Oral clearance normalized per body weight increased in children	Labeling	B	-	-	-	Parke-Davis	2/2/2000	FALSE'
MESH:D004827	12/10/2000	neurontin	gabapentin	Adjunctive therapy in the treatment of partial seizures	Safety and effectiveness established down to 3 years Neuropsychiatric AE's identified in 3-12 year olds Oral clearance normalized per body weight increased in children	Labeling	B	-	-	-	Parke-Davis	2/2/2000	FALSE'
MESH:D004827	12/10/2000	neurontin	gabapentin	Adjunctive therapy in the treatment of partial seizures	Safety and effectiveness established down to 3 years Neuropsychiatric AE's identified in 3-12 year olds Oral clearance normalized per body weight increased in children	Labeling	B	-	-	-	Parke-Davis	2/2/2000	FALSE'
MESH:D004827	12/10/2000	neurontin	gabapentin	Adjunctive therapy in the treatment of partial seizures	Safety and effectiveness established down to 3 years Neuropsychiatric AE's identified in 3-12 year olds Oral clearance normalized per body weight increased in children	Labeling	B	-	-	-	Parke-Davis	2/2/2000	FALSE'
MESH:D004827	12/10/2000	neurontin	gabapentin	Adjunctive therapy in the treatment of partial seizures	Safety and effectiveness established down to 3 years Neuropsychiatric AE's identified in 3-12 year olds Oral clearance normalized per body weight increased in children	Labeling	B	-	-	-	Parke-Davis	2/2/2000	FALSE'
MESH:D004827	01/13/2003	busulfex	busulfan	Part of a conditioning regimen administered prior to hematopoietic progenitor cell transplantation for a variety of malignant hematologic or non-malignant diseases	The population pharmacokinetic estimates of busulfan for clearance and volume of distribution were determined in an open-label, uncontrolled PK study in 24 pediatric patients 5 months to 16 years who received busulfan as part of a conditioning regimen administered prior to hematopoietic progenitor cell transplantation for a variety of malignant hematologic or non-malignant diseases Suggested dosing regimen	Labeling	B	-	-	-	Orphan Medical	12/3/2002	FALSE'
MESH:D004827	01/17/2003	lamictal	lamotrigine	Adjunctive therapy for partial seizures	Extended indication from adults to pediatric patients e 2 years Patients aged 2 - 18 years had clearance influenced predominantly by total body weight and concurrent antiepileptic drug (AED) therapy. The oral clearance was higher, on a body weight basis, in pediatric patients than in adults Because of increased clearance in pediatrics, maintenance doses in patients weighing < 30 kg may need an increase of as much as 50% based upon clinical response Evidence shows that the inclusion of VPA in a multi-drug regimen increases the risk of serious, potentially life-threatening rash in pediatric patients Approximately 11.5% of the 1,081 pediatric patients who received the drug as adjunctive therapy in clinical trials discontinued treatment because of an AE	Labeling	B	-	-	-	GlaxoSmithKline	02/14/2007	FALSE'
MESH:D004827	8/5/2009	lamictal	lamotrigine	Adjunctive treatment for partial seizures in pediatric patients 1 24 months	Safety and effectiveness as adjunctive treatment for partial seizures were not demonstrated in a small randomized, double-blind, placebo-controlled, withdrawal study in pediatric patients 1 - 24 months Immediate release tablets were associated with an increased risk for infectious adverse reactions including bronchiolitis, bronchitis, ear infection, eye infection, otitis externa, pharyngitis, urinary tract infection, and viral infection (Lamictal 37%, Placebo 5%), and respiratory adverse reactions including nasal congestion, cough, and apnea. (Lamictal 26%, Placebo 5%)	Labeling	B	-	-	-	GlaxoSmithKline	02/14/2007	FALSE'
MESH:D004827	05/18/2015	lamictal	lamotrigine	Maintenance treatment of bipolar disorder	Safety and efficacy for the maintenance treatment of bipolar disorder were not established in a double-blind, placebo-controlled trial that evaluated 301 pediatric patients aged 10 to 17 Information on clinical trial and adverse reactions Postmarketing study	Labeling	-	P	-	-	GlaxoSmithKline	-	FALSE
MESH:D004827	05/29/2009	lamictal xr	lamotrigine	Adjunctive therapy for partial onset seizures in patients e13 years of age	Extended release tablets are indicated as adjunctive therapy for partial onset seizures with or without secondary generalization in patients e13 years Safety and effectiveness of extended release tablets for any use in patients below the age of 13 have not been established Information on adverse event profile, and clinical studies New dosage form	Labeling	-	P	-	-	GlaxoSmithKline	-	FALSE'
MESH:D004827	01/29/2010	lamictal xr	lamotrigine	Adjunctive therapy for Primary Generalized Tonic-Clonic seizures	New indication for adjunctive therapy for primary generalized tonic-clonic seizures in patients e 13 years of age Safety and effectiveness for any use in patients < 13 years have not been established Information on dosing, adverse reactions, and clinical studies	Labeling	-	P	-	-	GlaxoSmithKline	-	FALSE'
MESH:D004827	04/25/2011	lamictal xr	lamotrigine	Monotherapy in patients 13 years of age and older with partial seizures who are receiving therapy with a single antiepileptic drug (AED)	Approved for conversion to monotherapy in patients e13 years of age with partial seizures receiving treatment with a single antiepileptic drug (AED).Safety and effectiveness have not been established (1) as initial monotherapy or (2) for simultaneous conversion to monotherapy from two or more concomitant AEDsInformation on conversion to monotherapy, adverse reactions, clinical trialNew indication	Labeling	-	P	-	-	GlaxoSmithKline	-	FALSE'
MESH:D004827	03/25/2004	cipro	ciprofloxacin	Complicated UTI and pyelonephritis	Indicated for the treatment of complicated urinary tract infections (cUTIs) and pyelonephritis in pediatric patients 1 17 years of age Not drug of first choice due to increased adverse events compared to controls including events related to joints and/or surrounding tissues Information on PK and dose in pediatric patients 1 17 years of age The most frequent adverse events observed within 6 weeks of treatment initiation during the cUTI clinical trial were gastrointestinal 15% compared to 9% and musculoskeletal 9.3% compared to 6% in ciprofloxacin-treated compared to control-treated patients, respectively	Labeling	B	-	-	-	Bayer	12/18/2003	FALSE'
MESH:D004827	03/25/2004	cipro	ciprofloxacin	Complicated UTI and pyelonephritis	Indicated for the treatment of complicated urinary tract infections (cUTIs) and pyelonephritis in pediatric patients 1 17 years of age Not drug of first choice due to increased adverse events compared to controls including events related to joints and/or surrounding tissues Information on PK and dose in pediatric patients 1 17 years of age The most frequent adverse events observed within 6 weeks of treatment initiation during the cUTI clinical trial were gastrointestinal 15% compared to 9% and musculoskeletal 9.3% compared to 6% in ciprofloxacin-treated compared to control-treated patients, respectively	Labeling	B	-	-	-	Bayer	12/18/2003	FALSE'
MESH:D004827	12/22/2009	topamax	topiramate	Migraine Prophylaxis	Safety and effectiveness for migraine prevention in pediatric patients have not been established Dose-related increased shift in serum creatinine in adolescent patients occurred in a clinical study Information added to Warnings and Precautions and Pediatric Use	Labeling	-	P	-	-	Ortho-McNeil-Janssen	-	FALSE'
MESH:D004827	12/22/2009	topamax	topiramate	Migraine Prophylaxis	Safety and effectiveness for migraine prevention in pediatric patients have not been established Dose-related increased shift in serum creatinine in adolescent patients occurred in a clinical study Information added to Warnings and Precautions and Pediatric Use	Labeling	-	P	-	-	Ortho-McNeil-Janssen	-	FALSE'
MESH:D004827	12/22/2009	topamax	topiramate	Adjunctive Treatment for Partial Onset Epilepsy in Infants and Toddlers 1 to 24 months	Effectiveness was not demonstrated as adjunctive therapy in a randomized, double-blind trial in infants/toddlers 1 to 24 months of age with refractory partial onset seizures Trials in infants/toddlers 1 to 24 months suggested some adverse reactions/toxicities not previously observed in older pediatric patients and adults; i.e, growth/length retardation, certain clinical laboratory abnormalities, and other adverse reactions/toxicities that occurred with a greater frequency and/or greater severity than had been recognized previously from studies in older pediatric patients or adults for various indications. Information added to Warnings and Precautions and Pediatric Use	Labeling	B	-	-	-	Ortho-McNeil-Janssen	07/24/2008	FALSE'
MESH:D004827	12/22/2009	topamax	topiramate	Adjunctive Treatment for Partial Onset Epilepsy in Infants and Toddlers 1 to 24 months	Effectiveness was not demonstrated as adjunctive therapy in a randomized, double-blind trial in infants/toddlers 1 to 24 months of age with refractory partial onset seizures Trials in infants/toddlers 1 to 24 months suggested some adverse reactions/toxicities not previously observed in older pediatric patients and adults; i.e, growth/length retardation, certain clinical laboratory abnormalities, and other adverse reactions/toxicities that occurred with a greater frequency and/or greater severity than had been recognized previously from studies in older pediatric patients or adults for various indications. Information added to Warnings and Precautions and Pediatric Use	Labeling	B	-	-	-	Ortho-McNeil-Janssen	07/24/2008	FALSE'
MESH:D004827	07/15/2011	topamax	topiramate	Monotherapy for partial onset or primary generalized tonic-clonic seizures	Expanded age range down to 2 years; previously approved for monotherapy for partial onset or primary generalized tonic-clonic seizures in patients10 years and older Information on weight based dosing in 2 to < 10 yearsPostmarketing study	Labeling	-	P	-	-	Janssen	-	FALSE'
MESH:D004827	07/15/2011	topamax	topiramate	Monotherapy for partial onset or primary generalized tonic-clonic seizures	Expanded age range down to 2 years; previously approved for monotherapy for partial onset or primary generalized tonic-clonic seizures in patients10 years and older Information on weight based dosing in 2 to < 10 yearsPostmarketing study	Labeling	-	P	-	-	Janssen	-	FALSE'
MESH:D004827	03/28/2014	topamax	topiramate	Prophylaxis of migraine headache	Approved for use in pediatric patients 12 years and older Safety and effectiveness in pediatric patients less than12 years have not been established for the prophylaxis treatment of migraine headache In the adolescent migraine trials (12 to 17 years), the most commonly observed adverse reactions were: paresthesia, upper respiratory tract infection, anorexia, and abdominal pain The most common cognitive adverse reaction in pooled double-blind studies in adolescent patients 12 to 17 years was difficulty with concentration/attention Markedly abnormally low serum bicarbonate values indicative of metabolic acidosis were reported in topiramate-treated adolescent migraine patients In topiramate-treated patients 12 to 17 years compared to placebo-treated patients, abnormally increased results were more frequent for creatinine, BUN, uric acid, chloride, ammonia, total protein, and platelets. Abnormally decreased results were observed with topiramate vs placebo treatment for phosphorus and bicarbonate Notable changes (increases and decreases) from baseline in systolic blood pressure, diastolic blood pressure, and pulse were observed more commonly in adolescents treated with topiramate compared to adolescents treated with placebo Information on dosing, adverse reactions, laboratory abnormalities, and clinical trials Postmarketing study	Labeling	-	P	-	-	Janssen	-	FALSE'
MESH:D004827	03/28/2014	topamax	topiramate	Prophylaxis of migraine headache	Approved for use in pediatric patients 12 years and older Safety and effectiveness in pediatric patients less than12 years have not been established for the prophylaxis treatment of migraine headache In the adolescent migraine trials (12 to 17 years), the most commonly observed adverse reactions were: paresthesia, upper respiratory tract infection, anorexia, and abdominal pain The most common cognitive adverse reaction in pooled double-blind studies in adolescent patients 12 to 17 years was difficulty with concentration/attention Markedly abnormally low serum bicarbonate values indicative of metabolic acidosis were reported in topiramate-treated adolescent migraine patients In topiramate-treated patients 12 to 17 years compared to placebo-treated patients, abnormally increased results were more frequent for creatinine, BUN, uric acid, chloride, ammonia, total protein, and platelets. Abnormally decreased results were observed with topiramate vs placebo treatment for phosphorus and bicarbonate Notable changes (increases and decreases) from baseline in systolic blood pressure, diastolic blood pressure, and pulse were observed more commonly in adolescents treated with topiramate compared to adolescents treated with placebo Information on dosing, adverse reactions, laboratory abnormalities, and clinical trials Postmarketing study	Labeling	-	P	-	-	Janssen	-	FALSE'
MESH:D004827	10/26/2013	sabril	vigabatrin	Refractory complex partial seizures (rCPS)	Approved as adjunctive therapy for pediatric patients 10 years and older with rCPS for whom the potential benefits outweigh the risk of vision loss. Sabril is not a first line agent for rCPS Safety and effectiveness for pediatric patients less than 10 years with refractory rCPS have not been established Pooled data from 3 controlled trials in pediatric patients demonstrated that 6% (10/165) of Sabril patients experienced somnolence compared to 5% (5/104) of placebo patients. In those same studies, 10% (17/165) of Sabril patients experienced fatigue compared to 7% (7/104) of placebo patients; 47% (77/163) of Sabril patients versus 19% (19/102) of placebo patients gained greater than or equal to 7% of baseline body weight Adverse reactions (ARs) in the pediatric population were similar to those reported in adults. Overall, ARs in pediatric patients 10-16 years included increased weight, upper respiratory tract infection, tremor, fatigue, aggression and diplopia Information on weight based dosing, dosing in renal impairment, safety information and clinical trials	Labeling	-	-	B,P	-	Lundbeck LLC	3/10/2013	FALSE'
MESH:D004827	10/26/2013	sabril	vigabatrin	Refractory complex partial seizures (rCPS)	Approved as adjunctive therapy for pediatric patients 10 years and older with rCPS for whom the potential benefits outweigh the risk of vision loss. Sabril is not a first line agent for rCPS Safety and effectiveness for pediatric patients less than 10 years with refractory rCPS have not been established Pooled data from 3 controlled trials in pediatric patients demonstrated that 6% (10/165) of Sabril patients experienced somnolence compared to 5% (5/104) of placebo patients. In those same studies, 10% (17/165) of Sabril patients experienced fatigue compared to 7% (7/104) of placebo patients; 47% (77/163) of Sabril patients versus 19% (19/102) of placebo patients gained greater than or equal to 7% of baseline body weight Adverse reactions (ARs) in the pediatric population were similar to those reported in adults. Overall, ARs in pediatric patients 10-16 years included increased weight, upper respiratory tract infection, tremor, fatigue, aggression and diplopia Information on weight based dosing, dosing in renal impairment, safety information and clinical trials	Labeling	-	-	B,P	-	Lundbeck LLC	3/10/2013	FALSE'
MESH:D004827	12/22/2016	lyrica	pregabalin	Fibromyalgia	Safety and efficacy in pediatric patients have not been established. A 15-week, placebo-controlled trial was conducted with 107 pediatric patients with fibromyalgia, ages 12 through 17 years . The primary efficacy endpoint of change from baseline to Week 15 in mean pain intensity showed numerically greater improvement for the pregabalin-treated patients compared to placebo-treated patients, but did not reach statistical significance. The most frequently observed adverse reactions in the clinical trial included dizziness, nausea, headache, weight increased, and fatigue. The overall safety profile in adolescents was similar to that observed in adults with fibromyalgia. Postmarketing study.	Labeling	-	P	-	-	PF Prism CV	-	FALSE
MESH:D004827	12/22/2016	lyrica	pregabalin	Fibromyalgia	Safety and efficacy in pediatric patients have not been established. A 15-week, placebo-controlled trial was conducted with 107 pediatric patients with fibromyalgia, ages 12 through 17 years . The primary efficacy endpoint of change from baseline to Week 15 in mean pain intensity showed numerically greater improvement for the pregabalin-treated patients compared to placebo-treated patients, but did not reach statistical significance. The most frequently observed adverse reactions in the clinical trial included dizziness, nausea, headache, weight increased, and fatigue. The overall safety profile in adolescents was similar to that observed in adults with fibromyalgia. Postmarketing study.	Labeling	-	P	-	-	PF Prism CV	-	FALSE
MESH:D004827	12/22/2016	lyrica	pregabalin	Fibromyalgia	Safety and efficacy in pediatric patients have not been established. A 15-week, placebo-controlled trial was conducted with 107 pediatric patients with fibromyalgia, ages 12 through 17 years . The primary efficacy endpoint of change from baseline to Week 15 in mean pain intensity showed numerically greater improvement for the pregabalin-treated patients compared to placebo-treated patients, but did not reach statistical significance. The most frequently observed adverse reactions in the clinical trial included dizziness, nausea, headache, weight increased, and fatigue. The overall safety profile in adolescents was similar to that observed in adults with fibromyalgia. Postmarketing study.	Labeling	-	P	-	-	PF Prism CV	-	FALSE