PedAM
Pediatric Disease Annotations & Medicines
| epidural abscess | ||||
| Disease ID | 1521 |
|---|---|
| Disease | epidural abscess |
| Definition | Circumscribed collections of suppurative material occurring in the spinal or intracranial EPIDURAL SPACE. The majority of epidural abscesses occur in the spinal canal and are associated with OSTEOMYELITIS of a vertebral body; ANALGESIA, EPIDURAL; and other conditions. Clinical manifestations include local and radicular pain, weakness, sensory loss, URINARY INCONTINENCE, and FECAL INCONTINENCE. Cranial epidural abscesses are usually associated with OSTEOMYELITIS of a cranial bone, SINUSITIS, or OTITIS MEDIA. (From Adams et al., Principles of Neurology, 6th ed, p710 and pp1240-1; J Neurol Neurosurg Psychiatry 1998 Aug;65(2):209-12) |
| Synonym | abscess, epidural abscess, extradural abscesses epidural epidural abscess (disorder) epidural abscess [disease/finding] extradural abscess |
| DOID | |
| UMLS | C0270629 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:28) C0012624 | spondylodiscitis | 19 C0029443 | osteomyelitis | 11 C0025289 | meningitis | 5 C0003864 | arthritis | 2 C0026975 | myelitis | 2 C0038012 | spondylitis | 2 C1704275 | pyomyositis | 2 C0014118 | endocarditis | 2 C0392548 | cauda equina syndrome | 2 C0034372 | tetraplegia | 1 C0022658 | renal disease | 1 C0011847 | diabetes | 1 C0041188 | tropical pyomyositis | 1 C0037944 | spinal stenosis | 1 C0025295 | pneumococcal meningitis | 1 C0003873 | rheumatoid arthritis | 1 C0010346 | crohn's disease | 1 C0011849 | diabetes mellitus | 1 C0151740 | intracranial hypertension | 1 C0003874 | septic arthritis | 1 C0022661 | end-stage renal disease | 1 C0006309 | brucellosis | 1 C0011334 | cavities | 1 C0020538 | hypertension | 1 C0018203 | chronic granulomatous disease | 1 C0030486 | paraplegia | 1 C0037199 | sinusitis | 1 C1565489 | renal insufficiency | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:23) 84245 | MRI1 | DISEASES 2645 | GCK | DISEASES 3110 | MNX1 | DISEASES 1401 | CRP | DISEASES 590 | BCHE | DISEASES 56606 | SLC2A9 | DISEASES 593 | BCKDHA | DISEASES 2495 | FTH1 | DISEASES 199699 | DAND5 | DISEASES 923 | CD6 | DISEASES 3052 | HCCS | DISEASES 6938 | TCF12 | DISEASES 7080 | NKX2-1 | DISEASES 26580 | BSCL2 | DISEASES 56955 | MEPE | DISEASES 28514 | DLL1 | DISEASES 2316 | FLNA | DISEASES 5453 | POU3F1 | DISEASES 650 | BMP2 | DISEASES 3440 | IFNA2 | DISEASES 6164 | RPL34 | DISEASES 3712 | IVD | DISEASES 10687 | PNMA2 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1521 |
|---|---|
| Disease | epidural abscess |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:26) HP:0002754 | Bone infection | 9 HP:0002176 | Spinal cord compression | 5 HP:0001287 | Meningitis | 5 HP:0100806 | Sepsis | 2 HP:0001369 | Arthritis | 2 HP:0012531 | Pain | 2 HP:0100584 | Endocarditis | 2 HP:0012486 | Inflammation of spinal cord | 2 HP:0001945 | Fever | 1 HP:0002273 | Tetraparesis | 1 HP:0001254 | Lethargy | 1 HP:0000083 | Renal insufficiency | 1 HP:0003095 | Septic arthritis | 1 HP:0000822 | Hypertension | 1 HP:0002664 | Neoplasia | 1 HP:0002445 | Paralysis of all four limbs | 1 HP:0001370 | Rheumatoid arthritis | 1 HP:0003416 | Spinal canal stenosis | 1 HP:0000819 | Diabetes mellitus | 1 HP:0002385 | Paraparesis | 1 HP:0002025 | Narrowing of anal opening | 1 HP:0003201 | Rhabdomyolysis | 1 HP:0010550 | Paraplegia | 1 HP:0002516 | Intracranial pressure elevation | 1 HP:0003774 | End-stage renal failure | 1 HP:0100280 | Morbus Crohn | 1 |
| Disease ID | 1521 |
|---|---|
| Disease | epidural abscess |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:4) C0012624 | spondylodiscitis | 17 C0452221 | vertebral osteomyelitis | 7 C0037926 | spinal cord compression | 5 C0006309 | brucellosis | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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GWASdb Annotation(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0270629 | vancomycin | D014640 | 1404-90-6 | epidural abscess | MESH:D020802 | therapeutic | 11171681 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |