PedAM

Pediatric Disease Annotations & Medicines


	ectropion

Disease ID	1553
Disease	ectropion
Definition	The turning outward (eversion) of the edge of the eyelid, resulting in the exposure of the palpebral conjunctiva. (Dorland, 27th ed)
Synonym	ectropion (disorder) ectropion (m-31318) ectropion [disease/finding] ectropion eyelids ectropion nos ectropion nos (disorder) ectropion of eyelid ectropion of eyelid (disorder) ectropion, nos ectropion, unspecified ectropions eversion of the eyelid everted eyelid everted margin everted margin (morphologic abnormality) extropion eyelashes turned out eyelid ectropion eyelid everted eyelid folded out eyelid turned out unspecified ectropion unspecified ectropion (disorder)
DOID	DOID:1570
UMLS	C0013592
MeSH	D004483
SNOMED-CT	SNOMEDCT_US_2016_09_01:62909004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:24) C0017601 \| glaucoma \| 3 C0020758 \| lamellar ichthyosis \| 2 C0005745 \| ptosis \| 2 C0003076 \| aniridia \| 2 C0037274 \| skin disease \| 1 C0031099 \| periodontitis \| 1 C0162359 \| hypohidrotic ectodermal dysplasia \| 1 C0032027 \| pityriasis rubra pilaris \| 1 C0085113 \| neurofibromatosis \| 1 C0005741 \| blepharitis \| 1 C0020302 \| developmental glaucoma \| 1 C0009763 \| conjunctivitis \| 1 C0409974 \| lupus erythematosus \| 1 C0022568 \| keratitis \| 1 C0020302 \| juvenile glaucoma \| 1 C0013575 \| ectodermal dysplasia \| 1 C0155145 \| chronic conjunctivitis \| 1 C0010495 \| cutis laxa \| 1 C0376358 \| prostate cancer \| 1 C0152226 \| lagophthalmos \| 1 C0007117 \| basal cell carcinoma \| 1 C0152227 \| epiphora \| 1 C0037274 \| skin diseases \| 1 C0235270 \| keratopathy \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:71) 4653 \| MYOC \| DISEASES 3861 \| KRT14 \| DISEASES 7145 \| TNS1 \| DISEASES 7051 \| TGM1 \| DISEASES 55612 \| FERMT1 \| DISEASES 1723 \| DHODH \| DISEASES 13 \| AADAC \| DISEASES 374291 \| NDUFS7 \| DISEASES 3848 \| KRT1 \| DISEASES 29969 \| MDFIC \| DISEASES 1545 \| CYP1B1 \| DISEASES 23314 \| SATB2 \| DISEASES 10133 \| OPTN \| DISEASES 80725 \| SRCIN1 \| DISEASES 3858 \| KRT10 \| DISEASES 126410 \| CYP4F22 \| DISEASES 26154 \| ABCA12 \| DISEASES 5295 \| PIK3R1 \| DISEASES 4851 \| NOTCH1 \| DISEASES 204219 \| CERS3 \| DISEASES 760 \| CA2 \| DISEASES 6529 \| SLC6A1 \| DISEASES 5304 \| PIP \| DISEASES 1409 \| CRYAA \| DISEASES 121214 \| SDR9C7 \| DISEASES 10999 \| SLC27A4 \| DISEASES 4909 \| NTF4 \| DISEASES 332 \| BIRC5 \| DISEASES 51181 \| DCXR \| DISEASES 5308 \| PITX2 \| DISEASES 1816 \| DRD5 \| DISEASES 392 \| ARHGAP1 \| DISEASES 348938 \| NIPAL4 \| DISEASES 59344 \| ALOXE3 \| DISEASES 242 \| ALOX12B \| DISEASES 57381 \| RHOJ \| DISEASES 923 \| CD6 \| DISEASES 2 \| A2M \| DISEASES 2303 \| FOXC2 \| DISEASES 1538 \| CYLC1 \| DISEASES 668 \| FOXL2 \| DISEASES 26151 \| NAT9 \| DISEASES 4763 \| NF1 \| DISEASES 147409 \| DSG4 \| DISEASES 4014 \| LOR \| DISEASES 7390 \| UROS \| DISEASES 2312 \| FLG \| DISEASES 4952 \| OCRL \| DISEASES 26508 \| HEYL \| DISEASES 7403 \| KDM6A \| DISEASES 285440 \| CYP4V2 \| DISEASES 5080 \| PAX6 \| DISEASES 2296 \| FOXC1 \| DISEASES 352909 \| DNAAF3 \| DISEASES 285848 \| PNPLA1 \| DISEASES 1365 \| CLDN3 \| DISEASES 643418 \| LIPN \| DISEASES 22976 \| PAXIP1 \| DISEASES 55777 \| MBD5 \| DISEASES 51099 \| ABHD5 \| DISEASES 3481 \| IGF2 \| DISEASES 1638 \| DCT \| DISEASES 23705 \| CADM1 \| DISEASES 27151 \| CPAMD8 \| DISEASES 9278 \| ZBTB22 \| DISEASES 117581 \| TWIST2 \| DISEASES 54900 \| LAX1 \| DISEASES 81704 \| DOCK8 \| DISEASES 134430 \| WDR36 \| DISEASES 2053 \| EPHX2 \| DISEASES 102723508 \| KANTR \| DISEASES
Locus	(Waiting for update.)

Disease ID	1553
Disease	ectropion
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:24) HP:0000501 \| Glaucoma \| 3 HP:0000508 \| Drooping upper eyelid \| 3 HP:0100699 \| Scarring \| 2 HP:0000526 \| Absent iris \| 2 HP:0011498 \| Partial aniridia \| 2 HP:0000968 \| Ectodermal dysplasia \| 1 HP:0000509 \| Conjunctivitis \| 1 HP:0100693 \| Iridodonesis \| 1 HP:0000612 \| Iris coloboma \| 1 HP:0000166 \| Severe periodontal disease \| 1 HP:0002671 \| Basalioma \| 1 HP:0000589 \| Ocular coloboma \| 1 HP:0009926 \| Epiphora \| 1 HP:0000498 \| Inflammation of eyelids \| 1 HP:0000973 \| Dermatomegaly \| 1 HP:0007607 \| Hypohidrotic ectodermal dysplasia \| 1 HP:0012125 \| Prostate cancer \| 1 HP:0001128 \| Trichiasis of eyelid eyelashes \| 1 HP:0000704 \| Pyorrhea \| 1 HP:0001067 \| Neurofibromas \| 1 HP:0000491 \| Corneal inflammation \| 1 HP:0000637 \| Wide palpebral fissure \| 1 HP:0007417 \| Discoid lupus erythematosus \| 1 HP:0007529 \| Hidrotic ectodermal dysplasia \| 1

Disease ID	1553
Disease	ectropion
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:1) C0152227 \| epiphora \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:2)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0013592	fluorouracil	D005472	51-21-8	ectropion	MESH:D004483	marker/mechanism	12918558
C0013592	tretinoin	D014212	302-79-4	ectropion	MESH:D004483	marker/mechanism	1401316

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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