PedAM
Pediatric Disease Annotations & Medicines
| eating disorder | ||||
| Disease ID | 499 |
|---|---|
| Disease | eating disorder |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:9) C0011570 | depression | 18 C0002020 | alexithymia | 4 C0031212 | personality disorders | 3 C0006012 | borderline personality disorder | 3 C0151723 | hypomagnesemia | 1 C0013146 | drug abuse | 1 C0001973 | alcoholism | 1 C0233397 | psychological symptoms | 1 C0037317 | sleep disturbances | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:29) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs1042778 | 25773927 | 5021 | OXTR | umls:C0013473 | BeFree | We genotyped six single nucleotide polymorphisms, rs53576, rs237879, rs2228485, rs13316193, rs2254298 and rs1042778, located within the OXTR gene in Korean patients with eating disorders using the single-base extension method. | 0.000271442 | 2015 | OXTR | 3 | 8752859 | G | C,T |
| rs13077017 | 23568457 | 2317 | FLNB | umls:C0013473 | GWASCAT | Genetic variants associated with disordered eating. | 0.12 | 2013 | FLNB | 3 | 58120049 | C | T |
| rs13316193 | 25773927 | 5021 | OXTR | umls:C0013473 | BeFree | We genotyped six single nucleotide polymorphisms, rs53576, rs237879, rs2228485, rs13316193, rs2254298 and rs1042778, located within the OXTR gene in Korean patients with eating disorders using the single-base extension method. | 0.000271442 | 2015 | OXTR | 3 | 8761057 | T | C |
| rs138206701 | 23568457 | 5924 | RASGRF2 | umls:C0013473 | GWASCAT | Genetic variants associated with disordered eating. | 0.12 | 2013 | RASGRF2 | 5 | 81110747 | A | G |
| rs1800497 | 22683321 | 1815 | DRD4 | umls:C0013473 | BeFree | We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. | 0.000271442 | 2012 | ANKK1 | 11 | 113400106 | G | A |
| rs1800497 | 22683321 | 1813 | DRD2 | umls:C0013473 | BeFree | We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. | 0.001085767 | 2012 | ANKK1 | 11 | 113400106 | G | A |
| rs1800497 | 22683321 | 1312 | COMT | umls:C0013473 | BeFree | We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. | 0.005819831 | 2012 | ANKK1 | 11 | 113400106 | G | A |
| rs1800497 | 22683321 | 6531 | SLC6A3 | umls:C0013473 | BeFree | We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. | 0.002909916 | 2012 | ANKK1 | 11 | 113400106 | G | A |
| rs2228485 | 25773927 | 5021 | OXTR | umls:C0013473 | BeFree | We genotyped six single nucleotide polymorphisms, rs53576, rs237879, rs2228485, rs13316193, rs2254298 and rs1042778, located within the OXTR gene in Korean patients with eating disorders using the single-base extension method. | 0.000271442 | 2015 | OXTR | 3 | 8768017 | G | A |
| rs2254298 | 25773927 | 5021 | OXTR | umls:C0013473 | BeFree | We genotyped six single nucleotide polymorphisms, rs53576, rs237879, rs2228485, rs13316193, rs2254298 and rs1042778, located within the OXTR gene in Korean patients with eating disorders using the single-base extension method. | 0.000271442 | 2015 | OXTR | 3 | 8760542 | G | A |
| rs237879 | 25773927 | 5021 | OXTR | umls:C0013473 | BeFree | We genotyped six single nucleotide polymorphisms, rs53576, rs237879, rs2228485, rs13316193, rs2254298 and rs1042778, located within the OXTR gene in Korean patients with eating disorders using the single-base extension method. | 0.000271442 | 2015 | CAV3;SSUH2 | 3 | 8741758 | C | T |
| rs386539811 | 21047193 | 51738 | GHRL | umls:C0013473 | BeFree | No association of the neuropeptide Y (Leu7Pro) and ghrelin gene (Arg51Gln, Leu72Met, Gln90Leu) single nucleotide polymorphisms with eating disorders. | 0.003181358 | 2011 | NA | NA | NA | NA | NA |
| rs386596687 | 16362631 | 2693 | GHSR | umls:C0013473 | BeFree | In the present study, we examined the 171T/C polymorphism of the ghrelin receptor (growth hormone secretagogue receptor, GHSR) gene in patients diagnosed with EDs, because the subjects having ghrelin gene polymorphism (Leu72Met) was not detected in a Japanese population, previously. | 0.000542884 | 2006 | NA | NA | NA | NA | NA |
| rs386602118 | 21851847 | 627 | BDNF | umls:C0013473 | BeFree | The aim of this study was to determine the association between the gene variants of the BDNF Val66Met polymorphism and obesity in 300 healthy Caucasian children and adolescents of the same ethnic background of Croatian origin, subdivided according to the BMI percentile, but without any form of eating disorders. | 0.008067311 | 2012 | NA | NA | NA | NA | NA |
| rs386602118 | 15108194 | 627 | BDNF | umls:C0013473 | BeFree | Association between the brain-derived neurotrophic factor 196G/A polymorphism and eating disorders. | 0.008067311 | 2004 | NA | NA | NA | NA | NA |
| rs386602118 | 20573217 | 627 | BDNF | umls:C0013473 | BeFree | We have not found an association between Val66Met (G196A) polymorphism of the BDNF and ED in schoolchildren from general population. | 0.008067311 | 2010 | NA | NA | NA | NA | NA |
| rs386602118 | 20537407 | 627 | BDNF | umls:C0013473 | BeFree | The Met-allele of the BDNF Val66Met polymorphism has been associated with eating disorders, but the underlying mechanism of its contribution is not known. | 0.008067311 | 2011 | NA | NA | NA | NA | NA |
| rs386602118 | 19526739 | 627 | BDNF | umls:C0013473 | BeFree | One example of shared genetic risk is the brain-derived neurotrophic factor (BNDF) gene, in which the valine allele of the Val66Met amino acid polymorphism predisposes to obesity, whereas the methionine allele predisposes to eating disorders. | 0.008067311 | 2009 | NA | NA | NA | NA | NA |
| rs41423247 | 25220664 | 2908 | NR3C1 | umls:C0013473 | BeFree | In this pilot study, we tested the hypothesis that an interaction between common variants in the MR (rs5522) or GR gene (rs41423247) and stressful life events influences perfectionism levels in a group of patients with an eating disorder (ED; n = 113). | 0.000814326 | 2014 | NR3C1 | 5 | 143399010 | G | C |
| rs4680 | 22683321 | 1815 | DRD4 | umls:C0013473 | BeFree | We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. | 0.000271442 | 2012 | COMT;MIR4761 | 22 | 19963748 | G | A |
| rs4680 | 22683321 | 1312 | COMT | umls:C0013473 | BeFree | We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. | 0.005819831 | 2012 | COMT;MIR4761 | 22 | 19963748 | G | A |
| rs4680 | 22683321 | 1813 | DRD2 | umls:C0013473 | BeFree | We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. | 0.001085767 | 2012 | COMT;MIR4761 | 22 | 19963748 | G | A |
| rs4680 | 22683321 | 6531 | SLC6A3 | umls:C0013473 | BeFree | We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. | 0.002909916 | 2012 | COMT;MIR4761 | 22 | 19963748 | G | A |
| rs4684677 | 21047193 | 51738 | GHRL | umls:C0013473 | BeFree | No association of the neuropeptide Y (Leu7Pro) and ghrelin gene (Arg51Gln, Leu72Met, Gln90Leu) single nucleotide polymorphisms with eating disorders. | 0.003181358 | 2011 | GHRL;GHRLOS | 3 | 10286769 | T | A |
| rs53576 | 25773927 | 5021 | OXTR | umls:C0013473 | BeFree | We genotyped six single nucleotide polymorphisms, rs53576, rs237879, rs2228485, rs13316193, rs2254298 and rs1042778, located within the OXTR gene in Korean patients with eating disorders using the single-base extension method. | 0.000271442 | 2015 | OXTR | 3 | 8762685 | A | G |
| rs5522 | 25220664 | 2908 | NR3C1 | umls:C0013473 | BeFree | In this pilot study, we tested the hypothesis that an interaction between common variants in the MR (rs5522) or GR gene (rs41423247) and stressful life events influences perfectionism levels in a group of patients with an eating disorder (ED; n = 113). | 0.000814326 | 2014 | NR3C2 | 4 | 148436323 | C | T |
| rs696217 | 21047193 | 51738 | GHRL | umls:C0013473 | BeFree | No association of the neuropeptide Y (Leu7Pro) and ghrelin gene (Arg51Gln, Leu72Met, Gln90Leu) single nucleotide polymorphisms with eating disorders. | 0.003181358 | 2011 | GHRL;GHRLOS | 3 | 10289773 | G | T |
| rs7322916 | 23568457 | 51761 | ATP8A2 | umls:C0013473 | GWASCAT | Genetic variants associated with disordered eating. | 0.12 | 2013 | ATP8A2 | 13 | 25433839 | G | A |
| rs9939609 | 22797368 | 79068 | FTO | umls:C0013473 | BeFree | Fat mass and obesity-associated gene (FTO) in eating disorders: evidence for association of the rs9939609 obesity risk allele with bulimia nervosa and anorexia nervosa. | 0.000542884 | 2012 | FTO | 16 | 53786615 | T | A |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:56) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 1 | 1029805 | rs6689308 | A | G | rs6689308 | 23568457 | 5.62E-04 | NA | 0.09 | [0.037-0.137] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs6689308-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 1 | 1031060 | rs7545952 | A | G | rs7545952 | 23568457 | 1.68E-04 | NA | 0.18 | [0.083-0.271] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs7545952-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 1 | 152318161 | rs3120667 | A | G | rs3120667 | 23568457 | 2.00E-06 | NA | 0.12 | [0.069-0.167] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs3120667-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 1 | 218094151 | rs6604568 | G | A | rs6604568 | 22911880 | 2.33E-05 | NA | NA | NA | Up to 2,567 European ancestry individuals | European(2567) | ALL(2567) | EUR(2567) | ALL(2567) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | NA | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 1 | 229469350 | rs163771 | G | A | rs163771 | 23568457 | 6.80E-05 | NA | 0.09 | [0.044-0.132] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs163771-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 2 | 60126311 | rs145433814 | G | A | rs145433814 | 23568457 | 6.00E-06 | NA | 0.24 | [0.14-0.34] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs145433814-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 2 | 216901933 | rs934154 | C | T | rs934154 | 23568457 | 4.20E-05 | NA | 0.06 | [0.03-0.086] unit increase | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs934154-T | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 2 | 228668322 | rs13385901 | C | A | rs13385901 | 23568457 | 4.00E-06 | NA | 0.1 | [0.054-0.138] unit increase | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs13385901-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 2 | 228668322 | rs367819358 | CTT | CAA | rs13385901 | 23568457 | 4.00E-06 | NA | 0.1 | [0.054-0.138] unit increase | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs13385901-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 2 | 228670575 | rs10175070 | G | A | rs10175070 | 23568457 | 2.00E-06 | NA | 0.12 | [0.073-0.175] unit increase | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs10175070-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 2 | 232298076 | rs12475512 | G | A | rs12475512 | 23568457 | 7.00E-07 | NA | 0.11 | [0.065-0.151] unit increase | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs12475512-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 2 | 234210972 | rs6759896 | G | A | rs6759896 | 23568457 | 1.70E-04 | NA | 0.07 | [0.032-0.108] unit increase | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs6759896-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 3 | 31040503 | rs1506203 | G | T | rs1506203 | 23568457 | 8.00E-06 | NA | 0.08 | [0.048-0.118] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs1506203-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 3 | 58105776 | rs13077017 | C | T | rs13077017 | 23568457 | 1.00E-06 | NA | 0.07 | [0.044-0.102] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs13077017-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 3 | 76261820 | rs1516459 | T | C | rs1516459 | 23568457 | 3.00E-06 | NA | 0.27 | [0.16-0.38] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs1516459-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 3 | 119913188 | rs4676822 | G | T | rs4676822 | 23568457 | 1.07E-04 | NA | 0.1 | [0.049-0.153] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs4676822-T | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 3 | 156836906 | rs7624327 | G | A | rs7624327 | 22911880 | 3.00E-06 | Bulimia | 1.13 | [1.06-1.16] | Up to 2,567 European ancestry individuals | European(2567) | ALL(2567) | EUR(2567) | ALL(2567) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs7624327-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 3 | 170080752 | rs13101192 | C | G | rs13101192 | 23568457 | 3.80E-05 | NA | 0.07 | [0.038-0.11] unit increase | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs13101192-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 3 | 170117518 | rs4292231 | C | G | rs4292231 | 23568457 | 2.45E-04 | NA | 0.09 | [0.042-0.142] unit increase | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs4292231-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 4 | 759733 | rs6816483 | T | C | rs6816483 | 23568457 | 7.00E-04 | NA | 0.06 | [0.026-0.102] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs6816483-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 4 | 100395414 | rs148915469 | A | C | rs148915469 | 23568457 | 8.00E-06 | NA | 0.28 | [0.16-0.4] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs148915469-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 4 | 133326395 | rs7690467 | T | C | rs7690467 | 22911880 | 7.00E-06 | OCPD | 1.12 | [1.07-1.18] | Up to 2,567 European ancestry individuals | European(2567) | ALL(2567) | EUR(2567) | ALL(2567) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs7690467-T | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 4 | 156735439 | rs17033585 | G | A | rs17033585 | 23568457 | 2.52E-04 | NA | 0.13 | [0.058-0.198] unit increase | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs17033585-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 5 | 65228251 | rs251614 | G | C | rs251614 | 23568457 | 5.70E-05 | NA | 0.1 | [0.052-0.156] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs251614-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 5 | 80406566 | rs138206701 | A | G | rs138206701 | 23568457 | 1.00E-07 | NA | 0.33 | [0.21-0.45] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs138206701-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 5 | 80406566 | rs138206701 | A | G | rs138206701 | 23568457 | 4.00E-06 | NA | 0.43 | [0.24-0.61] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs138206701-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 5 | 140595183 | rs2910330 | G | A,C,T | rs2910330 | 23568457 | 5.07E-04 | NA | 0.08 | [0.035-0.127] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs2910330-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 5 | 140653258 | rs10044936 | C | T | rs10044936 | 23568457 | 1.20E-05 | NA | 0.15 | [0.081-0.221] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs10044936-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 5 | 140668925 | rs113951537 | G | T | rs113951537 | 23568457 | 9.77E-06 | NA | 0.16 | [0.089-0.237] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs113951537-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 5 | 179032488 | rs6894268 | A | G | rs6894268 | 22911880 | 3.00E-06 | Body Dissatisfaction | 1.44 | [0.84-2.04] unit increase | Up to 2,567 European ancestry individuals | European(2567) | ALL(2567) | EUR(2567) | ALL(2567) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs6894268-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 6 | 36084672 | rs7752459 | C | T | rs7752459 | 23568457 | 8.10E-05 | NA | 0.09 | [0.045-0.141] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs7752459-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 6 | 39117698 | rs2115200 | T | G | rs2115200 | 23568457 | 2.00E-06 | NA | 0.1 | [0.057-0.139] unit increase | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs2115200-T | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 6 | 131526505 | rs3777474 | A | G | rs3777474 | 23568457 | 8.10E-05 | NA | 0.05 | [0.026-0.082] unit increase | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs3777474-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 7 | 83114212 | rs2713189 | C | T | rs2713189 | 23568457 | 1.39E-04 | NA | 0.05 | [0.024-0.076] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs2713189-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 8 | 3156220 | rs142816172 | C | T | rs142816172 | 23568457 | 6.00E-06 | NA | 0.27 | [0.16-0.39] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs142816172-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 8 | 116110725 | rs218361 | G | A | rs218361 | 22911880 | 7.00E-06 | WF | 1.06 | [1.03-1.08] | Up to 2,567 European ancestry individuals | European(2567) | ALL(2567) | EUR(2567) | ALL(2567) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs218361-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 8 | 124122514 | rs2385165 | A | C | rs2385165 | 23568457 | 3.80E-05 | NA | 0.06 | [0.031-0.091] unit increase | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs2385165-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 8 | 134778342 | rs74566133 | C | T | rs74566133 | 23568457 | 7.00E-07 | NA | 0.25 | [0.15-0.35] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs74566133-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 9 | 130504070 | rs514024 | G | A | rs514024 | 23568457 | 5.00E-06 | NA | 0.06 | [0.036-0.086] unit increase | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs514024-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 10 | 12875208 | rs10906233 | C | T | rs10906233 | 23568457 | 4.00E-06 | NA | 0.29 | [0.17-0.41] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs10906233-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 10 | 70014230 | rs10998035 | C | T | rs10998035 | 23568457 | 4.00E-06 | NA | 0.15 | [0.086-0.216] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs10998035-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 10 | 91116790 | rs627524 | A | C | rs627524 | 23568457 | 1.83E-05 | NA | 0.08 | [0.04-0.112] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs627524-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 10 | 102764047 | rs807029 | C | T | rs807029 | 23568457 | 1.86E-04 | NA | 0.08 | [0.035-0.119] unit increase | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs807029-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 11 | 27670108 | rs10501087 | T | C | rs10501087 | 22911880 | 3.01E-05 | NA | NA | NA | Up to 2,567 European ancestry individuals | European(2567) | ALL(2567) | EUR(2567) | ALL(2567) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | NA | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 11 | 27679916 | rs6265 | C | T | rs6265 | 22911880 | 2.33E-05 | NA | NA | NA | Up to 2,567 European ancestry individuals | European(2567) | ALL(2567) | EUR(2567) | ALL(2567) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | NA | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 11 | 69978638 | rs2509175 | T | A | rs2509175 | 23568457 | 9.80E-05 | NA | 0.11 | [0.052-0.16] unit increase | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs2509175-T | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 12 | 39122853 | rs864324 | G | A | rs864324 | 23568457 | 6.20E-05 | NA | 0.05 | [0.027-0.079] unit decrease | 600 female cases; 1,921 female controls | NOPOP(2521) | ALL(2521) | NOPOP(2521) | ALL(2521) | Eating disorders (purging via substances) | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs864324-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 13 | 26007977 | rs7322916 | G | A | rs7322916 | 23568457 | 8.00E-07 | NA | 0.09 | [0.054-0.124] unit increase | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs7322916-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 15 | 47892298 | rs1898111 | G | A | rs1898111 | 22911880 | 8.00E-06 | OCPD | 1.15 | [1.08-1.22] | Up to 2,567 European ancestry individuals | European(2567) | ALL(2567) | EUR(2567) | ALL(2567) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs1898111-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 15 | 49221591 | rs10519201 | G | T | rs10519201 | 22911880 | 6.00E-06 | OCPD | 1.16 | [1.09-1.23] | Up to 2,567 European ancestry individuals | European(2567) | ALL(2567) | EUR(2567) | ALL(2567) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs10519201-T | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 16 | 10663627 | rs2221433 | T | G | rs2221433 | 23568457 | 5.00E-06 | NA | 0.09 | [0.05-0.124] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs2221433-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 17 | 3899643 | rs9914203 | G | A | rs9914203 | 23568457 | 2.96E-04 | NA | 0.22 | [0.099-0.339] unit increase | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs9914203-G | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 18 | 4721359 | rs1557305 | C | T | rs1557305 | 22911880 | 5.00E-06 | OCPD | 1.11 | [1.06-1.16] | Up to 2,567 European ancestry individuals | European(2567) | ALL(2567) | EUR(2567) | ALL(2567) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs1557305-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 19 | 18053340 | rs4808105 | T | C | rs4808105 | 23568457 | 3.67E-04 | NA | 0.07 | [0.029-0.101] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs4808105-C | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 20 | 15120744 | rs11087123 | A | G | rs11087123 | 23568457 | 3.83E-06 | NA | 0.12 | [0.068-0.172] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs11087123-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 20 | 15120744 | rs11087123 | A | G | rs11087123 | 23568457 | 4.00E-06 | NA | 0.12 | [0.069-0.171] unit decrease | 543 female cases; 1,116 female controls | NOPOP(1659) | ALL(1659) | NOPOP(1659) | ALL(1659) | Eating disorders | HPOID:0100738 | Abnormal eating behavior | DOID:8670 | eating disorder | NA | NA | NA | NA | Eating disorder | rs11087123-A | Twin Study | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
Chemical(Total Drugs:23) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0013473 | amphetamine | D000661 | 300-62-9 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 9294377 | ||
| C0013473 | capsaicin | D002211 | 404-86-4 | feeding and eating disorders | MESH:D001068 | therapeutic | 20688118 | ||
| C0013473 | carbimazole | D002231 | 22232-54-8 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 8223196 | ||
| C0013473 | chlorpromazine | D002746 | 50-53-3 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 4562464 | ||
| C0013473 | clozapine | D003024 | 5786-21-0 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 18004133 | ||
| C0013473 | cyproheptadine | D003533 | 129-03-3 | feeding and eating disorders | MESH:D001068 | therapeutic | 264413 | ||
| C0013473 | cisplatin | D002945 | 15663-27-1 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 19710391 | ||
| C0013473 | digoxin | D004077 | 20830-75-5 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 618505 | ||
| C0013473 | fenfluramine | D005277 | 458-24-2 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 8223940 | ||
| C0013473 | fluoxetine | D005473 | 54910-89-3 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 11439417 | ||
| C0013473 | fluvoxamine | D016666 | 54739-18-3 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 11439417 | ||
| C0013473 | hydroxyurea | D006918 | 127-07-1 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 4883783 | ||
| C0013473 | lidocaine | D008012 | 137-58-6 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 6952075 | ||
| C0013473 | lindane | D001556 | 58-89-9 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 1711699 | ||
| C0013473 | lovastatin | D008148 | 75330-75-5 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 7909021 | ||
| C0013473 | mazindol | D008454 | 22232-71-9 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 2266990 | ||
| C0013473 | mefloquine | D015767 | 53230-10-7 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 20964849 | ||
| C0013473 | methylphenidate | D008774 | 113-45-1 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 14595084 | ||
| C0013473 | nicotine | D009538 | - | feeding and eating disorders | MESH:D001068 | marker/mechanism | 9746444 | ||
| C0013473 | olanzapine | C076029 | 132539-06-1 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 18004133 | ||
| C0013473 | ropinirole | C046649 | 91374-21-9 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 16534128 | ||
| C0013473 | rosiglitazone | C089730 | - | feeding and eating disorders | MESH:D001068 | marker/mechanism | 25788674 | ||
| C0013473 | sulpiride | D013469 | 15676-16-1 | feeding and eating disorders | MESH:D001068 | marker/mechanism | 2529418 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |