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PedAM

Pediatric Disease Annotations & Medicines



   diabetic angiopathy
  

Disease ID 1303
Disease diabetic angiopathy
Definition
VASCULAR DISEASES that are associated with DIABETES MELLITUS.
Synonym
angiopathies, diabetic
angiopathy, diabetic
diabetic angiopathies
diabetic angiopathies [disease/finding]
diabetic vascular complication
diabetic vascular complications
diabetic vascular disease
diabetic vascular diseases
diabetic vascular disorder
vascular complication, diabetic
vascular complications, diabetic
vascular disease, diabetic
vascular diseases, diabetic
DOID
UMLS
C0011875
MeSH
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:3)
C0007222  |  cardiovascular disease  |  2
C0042373  |  vascular disease  |  2
C0022658  |  nephropathy  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:7)
NOS3  |  4846  |  CTD_human
HMOX1  |  3162  |  CTD_human
HP  |  3240  |  CTD_human
ALB  |  213  |  CTD_human
AGER  |  177  |  CTD_human
MTHFR  |  4524  |  CTD_human
ASS1  |  445  |  CTD_human
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:1)
4524  |  MTHFR  |  infer
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:119)
2288  |  FKBP4  |  DISEASES
10911  |  UTS2  |  DISEASES
5607  |  MAP2K5  |  DISEASES
7049  |  TGFBR3  |  DISEASES
2287  |  FKBP3  |  DISEASES
4313  |  MMP2  |  DISEASES
7392  |  USF2  |  DISEASES
23770  |  FKBP8  |  DISEASES
55033  |  FKBP14  |  DISEASES
5054  |  SERPINE1  |  DISEASES
5216  |  PFN1  |  DISEASES
6347  |  CCL2  |  DISEASES
11211  |  FZD10  |  DISEASES
2597  |  GAPDH  |  DISEASES
4057  |  LTF  |  DISEASES
338  |  APOB  |  DISEASES
4488  |  MSX2  |  DISEASES
11328  |  FKBP9  |  DISEASES
10365  |  KLF2  |  DISEASES
10053  |  AP1M2  |  DISEASES
3630  |  INS  |  DISEASES
239  |  ALOX12  |  DISEASES
3040  |  HBA2  |  DISEASES
348  |  APOE  |  DISEASES
9945  |  GFPT2  |  DISEASES
314  |  AOC2  |  DISEASES
2995  |  GYPC  |  DISEASES
7057  |  THBS1  |  DISEASES
7450  |  VWF  |  DISEASES
645  |  BLVRB  |  DISEASES
6403  |  SELP  |  DISEASES
5007  |  OSBP  |  DISEASES
2247  |  FGF2  |  DISEASES
3383  |  ICAM1  |  DISEASES
3487  |  IGFBP4  |  DISEASES
207  |  AKT1  |  DISEASES
5972  |  REN  |  DISEASES
2180  |  ACSL1  |  DISEASES
3672  |  ITGA1  |  DISEASES
231  |  AKR1B1  |  DISEASES
1636  |  ACE  |  DISEASES
2220  |  FCN2  |  DISEASES
1173  |  AP2M1  |  DISEASES
5130  |  PCYT1A  |  DISEASES
7412  |  VCAM1  |  DISEASES
4880  |  NPPC  |  DISEASES
3490  |  IGFBP7  |  DISEASES
213  |  ALB  |  DISEASES
5473  |  PPBP  |  DISEASES
4982  |  TNFRSF11B  |  DISEASES
4846  |  NOS3  |  DISEASES
161742  |  SPRED1  |  DISEASES
1613  |  DAPK3  |  DISEASES
3479  |  IGF1  |  DISEASES
3037  |  HAS2  |  DISEASES
2820  |  GPD2  |  DISEASES
4973  |  OLR1  |  DISEASES
2286  |  FKBP2  |  DISEASES
5598  |  MAPK7  |  DISEASES
8639  |  AOC3  |  DISEASES
23166  |  STAB1  |  DISEASES
998  |  CDC42  |  DISEASES
285  |  ANGPT2  |  DISEASES
60681  |  FKBP10  |  DISEASES
7358  |  UGDH  |  DISEASES
3996  |  LLGL1  |  DISEASES
3039  |  HBA1  |  DISEASES
55511  |  SAGE1  |  DISEASES
2837  |  UTS2R  |  DISEASES
2  |  A2M  |  DISEASES
10498  |  CARM1  |  DISEASES
6401  |  SELE  |  DISEASES
2621  |  GAS6  |  DISEASES
2152  |  F3  |  DISEASES
1908  |  EDN3  |  DISEASES
2289  |  FKBP5  |  DISEASES
3146  |  HMGB1  |  DISEASES
864  |  RUNX3  |  DISEASES
545  |  ATR  |  DISEASES
6035  |  RNASE1  |  DISEASES
389421  |  LIN28B  |  DISEASES
3240  |  HP  |  DISEASES
8556  |  CDC14A  |  DISEASES
8678  |  BECN1  |  DISEASES
23038  |  WDTC1  |  DISEASES
116841  |  SNAP47  |  DISEASES
462  |  SERPINC1  |  DISEASES
27022  |  FOXD3  |  DISEASES
7422  |  VEGFA  |  DISEASES
4318  |  MMP9  |  DISEASES
1907  |  EDN2  |  DISEASES
2739  |  GLO1  |  DISEASES
8473  |  OGT  |  DISEASES
4153  |  MBL2  |  DISEASES
1650  |  DDOST  |  DISEASES
5089  |  PBX2  |  DISEASES
177  |  AGER  |  DISEASES
7056  |  THBD  |  DISEASES
1536  |  CYBB  |  DISEASES
1906  |  EDN1  |  DISEASES
7114  |  TMSB4X  |  DISEASES
2281  |  FKBP1B  |  DISEASES
2280  |  FKBP1A  |  DISEASES
6696  |  SPP1  |  DISEASES
83989  |  FAM172A  |  DISEASES
23365  |  ARHGEF12  |  DISEASES
4052  |  LTBP1  |  DISEASES
23210  |  JMJD6  |  DISEASES
23705  |  CADM1  |  DISEASES
7124  |  TNF  |  DISEASES
6464  |  SHC1  |  DISEASES
3276  |  PRMT1  |  DISEASES
5478  |  PPIA  |  DISEASES
9404  |  LPXN  |  DISEASES
8972  |  MGAM  |  DISEASES
7786  |  MAP3K12  |  DISEASES
51303  |  FKBP11  |  DISEASES
3949  |  LDLR  |  DISEASES
344  |  APOC2  |  DISEASES
Locus(Waiting for update.)
Disease ID 1303
Disease diabetic angiopathy
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:1)
HP:0000112  |  Nephropathy  |  1
Disease ID 1303
Disease diabetic angiopathy
Manually Symptom(Waiting for update.)
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:3)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs207060024418399177AGERumls:C0011875BeFreeThe study was designed to evaluate the association of -374T/A and -429T/C polymorphism in the promoter region and Gly82Ser polymorphism in exon 3 region of RAGE gene with diabetic vascular complications in Indian population.0.1289873762013AGER632183666CT
rs38655629324418399177AGERumls:C0011875BeFreeThe study was designed to evaluate the association of -374T/A and -429T/C polymorphism in the promoter region and Gly82Ser polymorphism in exon 3 region of RAGE gene with diabetic vascular complications in Indian population.0.1289873762013NANANANANA
rs4880207289556648SOD2umls:C0011875GAD[Association between the rs4880 superoxide dismutase 2 (C>T) gene variant and coronary heart disease in diabetes mellitus.]0.0047340642010SOD26159692840AG
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:7)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0011875acetylcysteineD000111616-91-1diabetic angiopathiesMESH:D003925therapeutic25381014
C0011875diltiazemD00411042399-41-7diabetic angiopathiesMESH:D003925therapeutic1833434
C0011875enalaprilD00465675847-73-3diabetic angiopathiesMESH:D003925therapeutic17970755
C0011875metforminD008687657-24-9diabetic angiopathiesMESH:D003925therapeutic16385087
C0011875rosiglitazoneC089730-diabetic angiopathiesMESH:D003925therapeutic17970755
C0011875streptozocinD01331118883-66-4diabetic angiopathiesMESH:D003925marker/mechanism19690068
C0011875troglitazoneC05769397322-87-7diabetic angiopathiesMESH:D003925therapeutic12601628
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)