PedAM
Pediatric Disease Annotations & Medicines
| desmoplastic small round cell tumor | ||||
| Disease ID | 346 |
|---|---|
| Disease | desmoplastic small round cell tumor |
| Definition | A rare, aggressive soft tissue sarcoma that primarily affects adolescents and young adults. It is most commonly found in the abdomen. |
| Synonym | desmoplas. small round cell tumor desmoplastic small cell tumor desmoplastic small round cell tumor (morphologic abnormality) desmoplastic small round cell tumor [disease/finding] desmoplastic small round cell tumour desmoplastic small round-cell neoplasm desmoplastic small round-cell tumor desmoplastic small-cell tumor desmoplastic small-cell tumors dsrct polyphenotypic small round cell tumor small-cell tumor, desmoplastic small-cell tumors, desmoplastic tumor, desmoplastic small-cell tumors, desmoplastic small-cell |
| Orphanet | |
| DOID | |
| UMLS | C0281508 |
| MeSH | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:8) C1261473 | sarcoma | 2 C0019829 | hodgkin lymphoma | 1 C0024305 | non-hodgkin lymphoma | 1 C0020538 | hypertension | 1 C0155616 | secondary hypertension | 1 C0024299 | lymphoma | 1 C0034072 | cor pulmonale | 1 C0700251 | brachial plexopathy | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:2) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | Symbol | Locus(Total Locus:2) |
| Disease ID | 346 |
|---|---|
| Disease | desmoplastic small round cell tumor |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:18) HP:0002240 | Hepatomegaly HP:0001903 | Anemia HP:0003270 | Abdominal distention HP:0004326 | Cachexia HP:0100242 | Sarcoma HP:0100721 | Mediastinal lymphadenopathy HP:0002585 | Abnormality of the peritoneum HP:0001824 | Weight loss HP:0002595 | Ileus HP:0002894 | Neoplasm of the pancreas HP:0002017 | Nausea and vomiting HP:0001541 | Ascites HP:0100526 | Neoplasm of the lung HP:0002027 | Abdominal pain HP:0010788 | Testicular neoplasm HP:0100006 | Neoplasm of the central nervous system HP:0100615 | Ovarian neoplasm HP:0002716 | Lymphadenopathy |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:7) HP:0100242 | Sarcoma | 2 HP:0012539 | Non-Hodgkin lymphoma | 1 HP:0012189 | Hodgkin disease | 1 HP:0002665 | Lymphoma | 1 HP:0000822 | Hypertension | 1 HP:0002664 | Neoplasia | 1 HP:0001648 | Cor pulmonale | 1 |
| Disease ID | 346 |
|---|---|
| Disease | desmoplastic small round cell tumor |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:1) C0494165 | hepatic metastasis |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0002585 | Abnormality of the peritoneum | MP:0000662 | abnormal branching of the mammary ductal tree;HP:0000035 | Abnormality of the testis |
Mapped by homologous gene(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0100615 | Ovarian neoplasm | MP:0000260 | abnormal angiogenesis;HP:0001541 | Ascites |
Chemical(Total Drugs:3) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0281508 | cyclophosphamide | D003520 | 50-18-0 | desmoplastic small round cell tumor | MESH:D058405 | therapeutic | 10555010 | ||
| C0281508 | ifosfamide | D007069 | 3778-73-2 | desmoplastic small round cell tumor | MESH:D058405 | therapeutic | 10555010 | ||
| C0281508 | vincristine | D014750 | - | desmoplastic small round cell tumor | MESH:D058405 | therapeutic | 10555010 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |