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Pediatric Disease Annotations & Medicines



   dermatitis herpetiformis
  

Disease ID 138
Disease dermatitis herpetiformis
Definition
Rare, chronic, papulo-vesicular disease characterized by an intensely pruritic eruption consisting of various combinations of symmetrical, erythematous, papular, vesicular, or bullous lesions. The disease is strongly associated with the presence of HLA-B8 and HLA-DR3 antigens. A variety of different autoantibodies has been detected in small numbers in patients with dermatitis herpetiformis.
Synonym
dermatitis herpetiformis (disorder)
dermatitis herpetiformis [disease/finding]
dermatitis herpetiformis [dup] (disorder)
dermatitis, herpetiformis
dermatosis herpetiformis
dh - dermatitis herpetiformis
disease duhring's
disease, duhring
disease, duhring's
duhring dis
duhring disease
duhring's disease
duhring-brocq disease
duhrings dis
duhrings disease
herpetiformis dermatitis
Orphanet
DOID
ICD10
UMLS
C0011608
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:21)
C0024299  |  lymphoma  |  2
C0007570  |  gluten-sensitive enteropathy  |  2
C0015230  |  rash  |  1
C0007570  |  celiac disease  |  1
C0024305  |  non-hodgkin lymphoma  |  1
C0017152  |  gastritis  |  1
C0018799  |  heart disease  |  1
C0042900  |  vitiligo  |  1
C0263398  |  erythema elevatum diutinum  |  1
C0024141  |  systemic lupus erythematosus  |  1
C0019829  |  hodgkin lymphoma  |  1
C0007570  |  coeliac disease  |  1
C0206180  |  anaplastic large cell lymphoma  |  1
C0021831  |  enteropathy  |  1
C0013595  |  eczema  |  1
C0409974  |  lupus erythematosus  |  1
C0242379  |  lung cancer  |  1
C0027873  |  neuromyelitis optica  |  1
C0151436  |  leukocytoclastic vasculitis  |  1
C0024302  |  large cell lymphoma  |  1
C0010068  |  coronary heart disease  |  1
Curated Gene(Waiting for update.)
Inferring Gene(Waiting for update.)
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:83)
343641  |  TGM6  |  DISEASES
973  |  CD79A  |  DISEASES
51200  |  CPA4  |  DISEASES
3458  |  IFNG  |  DISEASES
3565  |  IL4  |  DISEASES
3567  |  IL5  |  DISEASES
28981  |  IFT81  |  DISEASES
667  |  DST  |  DISEASES
5199  |  CFP  |  DISEASES
92797  |  HELB  |  DISEASES
1215  |  CMA1  |  DISEASES
2006  |  ELN  |  DISEASES
3911  |  LAMA5  |  DISEASES
3337  |  DNAJB1  |  DISEASES
1830  |  DSG3  |  DISEASES
1828  |  DSG1  |  DISEASES
1823  |  DSC1  |  DISEASES
2694  |  GIF  |  DISEASES
8728  |  ADAM19  |  DISEASES
4316  |  MMP7  |  DISEASES
10162  |  LPCAT3  |  DISEASES
7188  |  TRAF5  |  DISEASES
3290  |  HSD11B1  |  DISEASES
1991  |  ELANE  |  DISEASES
3938  |  LCT  |  DISEASES
3371  |  TNC  |  DISEASES
170589  |  GPHA2  |  DISEASES
4319  |  MMP10  |  DISEASES
11167  |  FSTL1  |  DISEASES
1359  |  CPA3  |  DISEASES
4314  |  MMP3  |  DISEASES
6866  |  TAC3  |  DISEASES
94235  |  GNG8  |  DISEASES
6356  |  CCL11  |  DISEASES
5036  |  PA2G4  |  DISEASES
5340  |  PLG  |  DISEASES
1657  |  DMXL1  |  DISEASES
5519  |  PPP2R1B  |  DISEASES
1240  |  CMKLR1  |  DISEASES
2907  |  GRINA  |  DISEASES
4026  |  LPP  |  DISEASES
10409  |  BASP1  |  DISEASES
4312  |  MMP1  |  DISEASES
5339  |  PLEC  |  DISEASES
10669  |  CGREF1  |  DISEASES
5178  |  PEG3  |  DISEASES
2520  |  GAST  |  DISEASES
3320  |  HSP90AA1  |  DISEASES
1665  |  DHX15  |  DISEASES
10011  |  SRA1  |  DISEASES
3117  |  HLA-DQA1  |  DISEASES
1308  |  COL17A1  |  DISEASES
7177  |  TPSAB1  |  DISEASES
1861  |  TOR1A  |  DISEASES
2204  |  FCAR  |  DISEASES
3240  |  HP  |  DISEASES
85301  |  COL27A1  |  DISEASES
219844  |  HYLS1  |  DISEASES
5625  |  PRODH  |  DISEASES
9464  |  HAND2  |  DISEASES
4976  |  OPA1  |  DISEASES
7052  |  TGM2  |  DISEASES
51696  |  HECA  |  DISEASES
3428  |  IFI16  |  DISEASES
284486  |  THEM5  |  DISEASES
959  |  CD40LG  |  DISEASES
680  |  BRS3  |  DISEASES
5737  |  PTGFR  |  DISEASES
3118  |  HLA-DQA2  |  DISEASES
3105  |  HLA-A  |  DISEASES
8718  |  TNFRSF25  |  DISEASES
7053  |  TGM3  |  DISEASES
9467  |  SH3BP5  |  DISEASES
2524  |  FUT2  |  DISEASES
29994  |  BAZ2B  |  DISEASES
4650  |  MYO9B  |  DISEASES
23150  |  FRMD4B  |  DISEASES
3119  |  HLA-DQB1  |  DISEASES
3120  |  HLA-DQB2  |  DISEASES
720  |  C4A  |  DISEASES
3115  |  HLA-DPB1  |  DISEASES
721  |  C4B  |  DISEASES
8754  |  ADAM9  |  DISEASES
Locus(Waiting for update.)
Disease ID 138
Disease dermatitis herpetiformis
Integrated Phenotype
HPO | Name(Total Integrated Phenotypes:14)
HP:0002757  |  Recurrent fractures
HP:0012733  |  Macule
HP:0000989  |  Pruritus
HP:0200037  |  Skin vesicle
HP:0002960  |  Autoimmunity
HP:0010783  |  Erythema
HP:0100725  |  Lichenification
HP:0000964  |  Eczema
HP:0000969  |  Edema
HP:0002653  |  Bone pain
HP:0002024  |  Malabsorption
HP:0008066  |  Abnormal blistering of the skin
HP:0001025  |  Urticaria
HP:0001935  |  Microcytic anemia
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:14)
HP:0002665  |  Lymphoma  |  2
HP:0010783  |  Erythema  |  1
HP:0002608  |  Celiac disease  |  1
HP:0002242  |  Enteropathy  |  1
HP:0001045  |  Blotchy loss of skin color  |  1
HP:0002725  |  Systemic lupus erythematosus  |  1
HP:0012189  |  Hodgkin disease  |  1
HP:0005231  |  Chronic gastritis  |  1
HP:0200037  |  Skin vesicle  |  1
HP:0000964  |  Eczema  |  1
HP:0005263  |  Gastritis  |  1
HP:0012539  |  Non-Hodgkin lymphoma  |  1
HP:0000961  |  Cyanosis  |  1
HP:0000967  |  Petechiae  |  1
Disease ID 138
Disease dermatitis herpetiformis
Manually Symptom
UMLS  | Name(Total Manually Symptoms:41)
C1963165  |  malabsorption
C1368041  |  pancreatic somatostatinoma
C0848454  |  uterine carcinoma
C0679408  |  gastric lesion
C0679407  |  gastrointestinal dysfunction
C0409977  |  bullous systemic lupus erythematosus
C0340987  |  splenic atrophy
C0272132  |  drug-induced haemolytic anaemia
C0263367  |  koebner phenomenon
C0156084  |  gastric dysfunction
C0152025  |  polyneuropathies
C0151744  |  ischaemic heart disease
C0151313  |  sensory neuropathy
C0079746  |  immunoblastic sarcoma
C0037285  |  skin manifestations
C0037284  |  skin lesions
C0037274  |  skin diseases
C0034150  |  purpura
C0033680  |  protein-losing enteropathy
C0031256  |  petechiae
C0031117  |  peripheral neuropathy
C0029166  |  oral manifestations
C0025637  |  methaemoglobinaemia
C0024299  |  lymphoma
C0021831  |  intestinal disease
C0021831  |  enteropathy
C0017658  |  glomerulonephritis
C0017657  |  glomerulitis
C0017152  |  gastritis
C0015230  |  skin rash
C0015230  |  rash
C0013720  |  ehlers-danlos syndrome
C0011854  |  type 1 diabetes
C0011854  |  insulin-dependent diabetes mellitus
C0011633  |  polymyositis/dermatomyositis
C0007570  |  gluten-sensitive enteropathy
C0007570  |  gluten sensitive enteropathy
C0007570  |  gluten enteropathy
C0007570  |  coeliac syndrome
C0002886  |  macrocytic anaemia
C0002871  |  anaemia
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:8)
C0007570  |  gluten-sensitive enteropathy  |  2
C0024299  |  lymphoma  |  2
C0037284  |  skin lesions  |  1
C0017152  |  gastritis  |  1
C0031256  |  petechiae  |  1
C0021831  |  enteropathy  |  1
C0409977  |  bullous systemic lupus erythematosus  |  1
C0015230  |  rash  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:1)
HP ID HP Name MP ID MP Name Annotation
HP:0100651Type I diabetes mellitusMP:0004701decreased circulating insulin-like growth factor I level;HP:0002242Abnormality of the intestine
Mapped by homologous gene(Total Items:1)
HP ID HP Name MP ID MP Name Annotation
HP:0000099GlomerulonephritisMP:0005193abnormal anterior eye segment morphology;HP:0002665Lymphoma
Chemical(Total Drugs:1)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0011608dapsoneD00362280-08-0dermatitis herpetiformisMESH:D003874therapeutic10971353
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)