PedAM
Pediatric Disease Annotations & Medicines
| dengue hemorrhagic fever | ||||
| Disease ID | 805 |
|---|---|
| Disease | dengue hemorrhagic fever |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:19) HP:0001873 | Low platelet count | 7 HP:0001945 | Fever | 4 HP:0001733 | Pancreatic inflammation | 2 HP:0001298 | Encephalopathy | 2 HP:0001735 | Acute pancreatitis | 2 HP:0002098 | Respiratory distress | 1 HP:0000225 | Gingival hemorrhage | 1 HP:0003201 | Rhabdomyolysis | 1 HP:0001082 | Cholecystitis | 1 HP:0002664 | Neoplasia | 1 HP:0012819 | Myocarditis | 1 HP:0000952 | Yellow skin | 1 HP:0030005 | Capillary leak | 1 HP:0001953 | Diabetic ketosis | 1 HP:0001903 | Anemia | 1 HP:0012223 | Ruptured spleen | 1 HP:0002893 | Pituitary adenoma | 1 HP:0012234 | Agranulocytosis | 1 HP:0012151 | Hemothorax | 1 |
| Disease ID | 805 |
|---|---|
| Disease | dengue hemorrhagic fever |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:6) C0040034 | thrombocytopenia | 5 C0019080 | hemorrhage | 3 C0009450 | infection | 2 C0085584 | encephalopathy | 2 C1282609 | granulocytosis | 1 C0267842 | acute acalculous cholecystitis | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:7) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs1285933 | 24016730 | 23601 | CLEC5A | umls:C0019100 | BeFree | We demonstrated that the TT genotype of CLEC5A SNP (rs1285933 C>T) is associated with dengue severity (OR=2.25; p=0.03) and that GG genotype of -336G>A DCSIGN (CD209) SNP is associated with protection to severe dengue (OR=0.12; p=0.04). | 0.120542884 | 2013 | CLEC5A;OR9A4 | 7 | 141927349 | G | A |
| rs1285933 | 24016730 | 30835 | CD209 | umls:C0019100 | BeFree | We demonstrated that the TT genotype of CLEC5A SNP (rs1285933 C>T) is associated with dengue severity (OR=2.25; p=0.03) and that GG genotype of -336G>A DCSIGN (CD209) SNP is associated with protection to severe dengue (OR=0.12; p=0.04). | 0.000814326 | 2013 | CLEC5A;OR9A4 | 7 | 141927349 | G | A |
| rs1801274 | 24911936 | 2212 | FCGR2A | umls:C0019100 | BeFree | Two single nucleotide polymorphisms (SNPs), rs1801274 of FcγRIIa and rs4804803 of DC-SIGN, have been associated with protection from or susceptibility to severe dengue infection. | 0.000542884 | 2014 | FCGR2A | 1 | 161509955 | A | G |
| rs3765524 | 22001756 | 51196 | PLCE1 | umls:C0019100 | GAD | [Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1.] | 0.122638474 | 2011 | PLCE1 | 10 | 94298541 | C | T |
| rs4804803 | 21245921 | 30835 | CD209 | umls:C0019100 | BeFree | the rs4804803 SNP in the CD209 promoter contributed to susceptibility to dengue infection and complication of DHF. | 0.000814326 | 2011 | CD209 | 19 | 7747847 | A | G |
| rs4804803 | 24911936 | 2212 | FCGR2A | umls:C0019100 | BeFree | Two single nucleotide polymorphisms (SNPs), rs1801274 of FcγRIIa and rs4804803 of DC-SIGN, have been associated with protection from or susceptibility to severe dengue infection. | 0.000542884 | 2014 | CD209 | 19 | 7747847 | A | G |
| rs6500818 | 22001756 | 54715 | RBFOX1 | umls:C0019100 | GAD | [Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1.] | 0.002367032 | 2011 | RBFOX1 | 16 | 6767374 | C | T |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |