PedAM

Pediatric Disease Annotations & Medicines


	cryptogenic organizing pneumonia

Disease ID	461
Disease	cryptogenic organizing pneumonia
Definition	A disease formerly considered a form of interstitial pneumonia. Its etiology is obscure but it may be associated with toxic fumes, infection, and connective tissue disease. Clinical symptoms include cough, dyspnea and influenza-like symptoms with the development of the usual interstitial pneumonia in many cases. Obstructive symptoms are limited to smokers. There are patchy polypoid masses of intra-alveolar granulation tissue in small airway lumina and alveolar ducts. "Organizing" refers to unresolved pneumonia (in which the alveolar exudate persists and eventually undergoes fibrosis) in which fibrous tissue forms in the alveoli.(MeSH)
Synonym	boop boop - bronchiolitis obliterans and organising pneumonitis boop - bronchiolitis obliterans and organizing pneumonitis boop - bronchiolitis obliterans organising pneumonia boop - bronchiolitis obliterans organizing pneumonia bronchiolitis obliterans and organising pneumonitis bronchiolitis obliterans and organizing pneumonitis bronchiolitis obliterans organising pneumonia bronchiolitis obliterans organizing pneumonia bronchiolitis obliterans organizing pneumonia (boop) bronchiolitis obliterans organizing pneumonia (disorder) bronchiolitis obliterans with organising pneumonia bronchiolitis obliterans with organizing pneumonia cop - cryptogenic organising pneumonitis cop - cryptogenic organizing pneumonitis cryptogenic organising pneumonia cryptogenic organising pneumonitis cryptogenic organiz pneu cryptogenic organizing pneumonia (disorder) cryptogenic organizing pneumonia [disease/finding] cryptogenic organizing pneumonias cryptogenic organizing pneumonitis organizing pneumonia, cryptogenic organizing pneumonias, cryptogenic pneumonia, cryptogenic organizing pneumonias, cryptogenic organizing
Orphanet	ORPHANET:1302
DOID	DOID:0050157
ICD10	ICD10CM:J84.116
UMLS	C0242770
MeSH	D018549
SNOMED-CT	SNOMEDCT_US_2016_09_01:129458007
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:10) C0242770 \| cryptogenic organizing pneumonia \| 8 C0085253 \| adult onset still's disease \| 1 C0021400 \| influenza \| 1 C0004030 \| aspergillosis \| 1 C0027121 \| myositis \| 1 C0006272 \| bronchiolitis obliterans \| 1 C0003873 \| rheumatoid arthritis \| 1 C1145670 \| respiratory failure \| 1 C0006271 \| bronchiolitis \| 1 C0007120 \| bronchioloalveolar carcinoma \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:69) 6362 \| CCL18 \| DISEASES 920 \| CD4 \| DISEASES 1634 \| DCN \| DISEASES 7076 \| TIMP1 \| DISEASES 4313 \| MMP2 \| DISEASES 1512 \| CTSH \| DISEASES 7431 \| VIM \| DISEASES 6347 \| CCL2 \| DISEASES 3567 \| IL5 \| DISEASES 5657 \| PRTN3 \| DISEASES 54210 \| TREM1 \| DISEASES 968 \| CD68 \| DISEASES 10452 \| TOMM40 \| DISEASES 1401 \| CRP \| DISEASES 29109 \| FHOD1 \| DISEASES 3569 \| IL6 \| DISEASES 26525 \| IL36RN \| DISEASES 4316 \| MMP7 \| DISEASES 8766 \| RAB11A \| DISEASES 7077 \| TIMP2 \| DISEASES 3553 \| IL1B \| DISEASES 8626 \| TP63 \| DISEASES 1462 \| VCAN \| DISEASES 5286 \| PIK3C2A \| DISEASES 925 \| CD8A \| DISEASES 2215 \| FCGR3B \| DISEASES 152185 \| SPICE1 \| DISEASES 213 \| ALB \| DISEASES 3562 \| IL3 \| DISEASES 1437 \| CSF2 \| DISEASES 1672 \| DEFB1 \| DISEASES 3611 \| ILK \| DISEASES 1673 \| DEFB4A \| DISEASES 136 \| ADORA2B \| DISEASES 27087 \| B3GAT1 \| DISEASES 947 \| CD34 \| DISEASES 633 \| BGN \| DISEASES 9075 \| CLDN2 \| DISEASES 9094 \| UNC119 \| DISEASES 3932 \| LCK \| DISEASES 23583 \| SMUG1 \| DISEASES 1364 \| CLDN4 \| DISEASES 871 \| SERPINH1 \| DISEASES 1366 \| CLDN7 \| DISEASES 356 \| FASLG \| DISEASES 1805 \| DPT \| DISEASES 2214 \| FCGR3A \| DISEASES 4582 \| MUC1 \| DISEASES 4942 \| OAT \| DISEASES 2010 \| EMD \| DISEASES 959 \| CD40LG \| DISEASES 4318 \| MMP9 \| DISEASES 3339 \| HSPG2 \| DISEASES 444 \| ASPH \| DISEASES 51466 \| EVL \| DISEASES 51520 \| LARS \| DISEASES 1365 \| CLDN3 \| DISEASES 3965 \| LGALS9 \| DISEASES 3652 \| IPP \| DISEASES 51147 \| ING4 \| DISEASES 7122 \| CLDN5 \| DISEASES 7124 \| TNF \| DISEASES 388372 \| CCL4L1 \| DISEASES 7555 \| CNBP \| DISEASES 3586 \| IL10 \| DISEASES 23218 \| NBEAL2 \| DISEASES 727897 \| MUC5B \| DISEASES 401505 \| TOMM5 \| DISEASES 100128731 \| OST4 \| DISEASES
Locus	(Waiting for update.)

Disease ID	461
Disease	cryptogenic organizing pneumonia
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:8) HP:0011945 \| Cryptogenic organizing pneumonia \| 8 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0011946 \| Constrictive bronchiolitis \| 1 HP:0100614 \| Muscle inflammation \| 1 HP:0004313 \| Decreased immunoglobulin level \| 1 HP:0011950 \| Bronchiolitis \| 1 HP:0002878 \| Respiratory failure \| 1 HP:0030731 \| Carcinoma \| 1

Disease ID	461
Disease	cryptogenic organizing pneumonia
Manually Symptom	UMLS \| Name(Total Manually Symptoms:4) C0398367 \| kikuchi fujimoto disease C0240035 \| interstitial fibrosis C0036416 \| scleritis C0027121 \| myositis
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0027121 \| myositis \| 1 C0398367 \| kikuchi fujimoto disease \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0242770	phenytoin	D010672	57-41-0	cryptogenic organizing pneumonia	MESH:D018549	marker/mechanism	9404778

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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