PedAM

Pediatric Disease Annotations & Medicines


	crohn disease

Disease ID	39
Disease	crohn disease
Definition	A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
Synonym	-- crohn's disease cd - crohn's disease crohn dis crohn disease [disease/finding] crohn diseases crohn s crohn s disease crohn's crohn's disease crohn's disease (disorder) crohn's disease nos crohn's disease, nos crohn's diseases crohn's enteritis crohn's regional enteritis crohns dis crohns disease crohns diseases crohns's crohns's disease disease crohn disease crohn's disease crohns eleocolitis enteritis (regional) enteritis regional granulomatous enteritis granulomatous enteritis and colitis granulomatous enteritis, nos ibd1 inflammatory bowel disease (crohn disease) 1 inflammatory bowel disease 1 inflammatory bowel disease, regional enteritis morbus crohn re - regional enteritis regional enteritis regional enteritis (crohn's disease) regional enteritis - crohn regional enteritis - crohn's disease regional enteritis, nos
OMIM	OMIM:266600
DOID	DOID:8778
UMLS	C0010346
MeSH	D003424
SNOMED-CT	SNOMEDCT_US_2016_09_01:34000006
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:269) C0021831 \| bowel disease \| 30 C0021390 \| inflammatory bowel disease \| 23 C0009319 \| colitis \| 22 C0009324 \| ulcerative colitis \| 13 C0030524 \| paratuberculosis \| 11 C0024299 \| lymphoma \| 11 C0042384 \| vasculitis \| 9 C0001418 \| adenocarcinoma \| 8 C0002871 \| anemia \| 7 C0034212 \| pyoderma \| 7 C0002726 \| amyloidosis \| 7 C0009402 \| colorectal cancer \| 6 C0033860 \| psoriasis \| 6 C0008313 \| sclerosing cholangitis \| 6 C0040053 \| thrombosis \| 6 C0566602 \| primary sclerosing cholangitis \| 6 C0011991 \| diarrhea \| 6 C0007113 \| rectal cancer \| 6 C0003864 \| arthritis \| 6 C0019348 \| herpes simplex \| 5 C0021390 \| inflammatory bowel diseases \| 5 C0021843 \| bowel obstruction \| 5 C0085652 \| pyoderma gangrenosum \| 5 C0008311 \| cholangitis \| 5 C0019158 \| hepatitis \| 5 C0029443 \| osteomyelitis \| 4 C0039263 \| takayasu's arteritis \| 4 C0021843 \| intestinal obstruction \| 4 C0442874 \| neuropathy \| 4 C0010414 \| cryptococcosis \| 4 C0017661 \| iga nephropathy \| 4 C0023418 \| leukemia \| 4 C0024141 \| systemic lupus erythematosus \| 4 C0001339 \| acute pancreatitis \| 4 C0409974 \| lupus erythematosus \| 4 C0030305 \| pancreatitis \| 4 C0022658 \| nephropathy \| 4 C0021845 \| bowel perforation \| 3 C0003873 \| rheumatoid arthritis \| 3 C0042900 \| vitiligo \| 3 C0085160 \| hidradenitis \| 3 C0037198 \| sinus thrombosis \| 3 C0018202 \| granulomatous vasculitis \| 3 C0032285 \| pneumonia \| 3 C0023524 \| progressive multifocal leukoencephalopathy \| 3 C0032285 \| pneumonitis \| 3 C0270612 \| leukoencephalopathy \| 3 C0041296 \| tuberculosis \| 3 C0155223 \| dacryoadenitis \| 3 C1258215 \| ileus \| 3 C0343386 \| clostridium difficile infection \| 3 C0020875 \| ileal disease \| 3 C0036202 \| sarcoidosis \| 3 C0276688 \| pulmonary cryptococcosis \| 3 C0035258 \| restless legs syndrome \| 3 C0028754 \| obesity \| 3 C0035258 \| restless legs \| 3 C0016412 \| folate deficiency \| 3 C0029456 \| osteoporosis \| 3 C0011570 \| depression \| 3 C0003509 \| aortitis \| 2 C0025162 \| toxic megacolon \| 2 C0019829 \| hodgkin's lymphoma \| 2 C0027813 \| neuritis \| 2 C0029134 \| optic neuritis \| 2 C0553662 \| juvenile idiopathic arthritis \| 2 C0013298 \| duodenitis \| 2 C0027726 \| nephrotic syndrome \| 2 C0341335 \| cmv colitis \| 2 C0021831 \| enteropathy \| 2 C0021831 \| intestinal disease \| 2 C0025160 \| megacolon \| 2 C0007102 \| colon cancer \| 2 C0162429 \| malnutrition \| 2 C0162836 \| hidradenitis suppurativa \| 2 C0025289 \| meningitis \| 2 C0015230 \| rash \| 2 C0008350 \| gallstone \| 2 C0041321 \| miliary tuberculosis \| 2 C0021933 \| intussusception \| 2 C0042870 \| vitamin d deficiency \| 2 C0024523 \| malabsorption \| 2 C0030312 \| pancytopenia \| 2 C0009447 \| common variable immunodeficiency \| 2 C0008350 \| gallstones \| 2 C0017152 \| gastritis \| 2 C0007570 \| celiac disease \| 2 C0949691 \| spondyloarthropathy \| 2 C0019829 \| hodgkin lymphoma \| 2 C0007113 \| rectal carcinoma \| 2 C0023467 \| acute myeloid leukemia \| 2 C0040053 \| thrombus \| 2 C0018203 \| chronic granulomatous disease \| 2 C0040034 \| thrombocytopenia \| 2 C0022568 \| keratitis \| 2 C0030920 \| peptic ulcer \| 2 C0868908 \| pancolitis \| 2 C0042870 \| vitamin d defic \| 2 C0018021 \| goiter \| 2 C0026718 \| mucormycosis \| 2 C0031154 \| peritonitis \| 2 C0027121 \| myositis \| 2 C0023470 \| myeloid leukemia \| 2 C0031090 \| periodontal disease \| 2 C0019204 \| hepatocellular carcinoma \| 2 C0003467 \| anxiety \| 2 C0162429 \| nutritional deficiencies \| 1 C0014527 \| epidermolysis bullosa \| 1 C0038362 \| stomatitis \| 1 C0024291 \| hemophagocytic syndrome \| 1 C0023827 \| liposarcoma \| 1 C0019360 \| herpes zoster \| 1 C0023895 \| liver disease \| 1 C0949690 \| spondyloarthritis \| 1 C0034150 \| purpura \| 1 C0034065 \| pulmonary embolism \| 1 C0022104 \| irritable bowel \| 1 C0022806 \| kwashiorkor \| 1 C0334254 \| lymphoepithelioma \| 1 C0023418 \| leukaemia \| 1 C0024314 \| lymphoproliferative disorders \| 1 C0021390 \| irritable bowel disease \| 1 C0026769 \| multiple sclerosis \| 1 C0178238 \| intestinal infection \| 1 C0001418 \| adenocarcinomas \| 1 C0004030 \| aspergillosis \| 1 C0007137 \| squamous cell carcinoma \| 1 C0002878 \| hemolytic anemia \| 1 C0238463 \| papillary thyroid carcinoma \| 1 C0017178 \| gastrointestinal disorder \| 1 C0030524 \| johne's disease \| 1 C0042721 \| virus hepatitis \| 1 C0026946 \| fungal infection \| 1 C0005741 \| blepharitis \| 1 C0019163 \| hepatitis b \| 1 C0699790 \| colon carcinoma \| 1 C0025037 \| meckel's diverticulum \| 1 C0024291 \| hemophagocytic lymphohistiocytosis \| 1 C0022116 \| ischemia \| 1 C0031069 \| familial mediterranean fever \| 1 C0011334 \| cavities \| 1 C0037274 \| skin diseases \| 1 C0393819 \| chronic inflammatory demyelinating polyradiculoneuropathy \| 1 C0346627 \| intestinal cancers \| 1 C0041331 \| splenic tuberculosis \| 1 C0085253 \| adult onset still's disease \| 1 C0037274 \| dermatosis \| 1 C0008312 \| biliary cirrhosis \| 1 C0018920 \| cavernoma \| 1 C0032305 \| pneumocystis jiroveci pneumonia \| 1 C0024299 \| malignant lymphoma \| 1 C0024299 \| malignant lymphomas \| 1 C0024205 \| lymphadenitis \| 1 C0023487 \| acute promyelocytic leukaemia \| 1 C0023448 \| lymphoblastic leukemia \| 1 C0270629 \| epidural abscess \| 1 C0031099 \| periodontitis \| 1 C0007104 \| carcinoma of the breast \| 1 C0751878 \| central nervous system vasculitis \| 1 C0030805 \| pemphigoid \| 1 C0039263 \| takayasu's disease \| 1 C0009402 \| colorectal carcinoma \| 1 C0035078 \| kidney failure \| 1 C0037274 \| dermatoses \| 1 C0002880 \| autoimmune hemolytic anemia \| 1 C0036992 \| short bowel syndrome \| 1 C0003615 \| appendicitis \| 1 C0003125 \| anorexia nervosa \| 1 C0019348 \| herpes simplex infection \| 1 C0028756 \| morbid obesity \| 1 C0008312 \| primary biliary cirrhosis \| 1 C0085655 \| polymyositis \| 1 C0024440 \| cystoid macular oedema \| 1 C0011854 \| type 1 diabetes \| 1 C0035854 \| rosacea \| 1 C0004943 \| behcet's disease \| 1 C0023890 \| cirrhosis \| 1 C0038220 \| status epilepticus \| 1 C0042769 \| viral infection \| 1 C0036416 \| scleritis \| 1 C0279637 \| carcinoma of the anus \| 1 C0006625 \| cachectic \| 1 C0026986 \| myelodysplastic syndrome \| 1 C0029132 \| optic neuropathy \| 1 C0024214 \| lymphangiectasia \| 1 C1527336 \| sjogren's syndrome \| 1 C0031117 \| peripheral neuropathy \| 1 C0162293 \| papillitis \| 1 C0025290 \| aseptic meningitis \| 1 C0002871 \| anemias \| 1 C0001430 \| adenoma \| 1 C0014236 \| endophthalmitis \| 1 C0598608 \| hyperhomocysteinemia \| 1 C0038041 \| spotted fever \| 1 C0026946 \| fungal infections \| 1 C0376175 \| bell's palsy \| 1 C0751711 \| anterior ischemic optic neuropathy \| 1 C0005940 \| bone disease \| 1 C0043117 \| idiopathic thrombocytopenic purpura \| 1 C0079293 \| epidermolysis bullosa acquisita \| 1 C0024299 \| lymphomas \| 1 C0017919 \| glycogen storage disease \| 1 C0032305 \| pneumocystis \| 1 C0002991 \| dermatofibroma \| 1 C0017178 \| gastrointestinal disorders \| 1 C0017661 \| iga glomerulonephritis \| 1 C0024221 \| lymphangioma \| 1 C0392525 \| nephrolithiasis \| 1 C0085167 \| granular cell tumour \| 1 C1412036 \| squamous cell carcinoma of the anus \| 1 C0032305 \| pneumocystosis \| 1 C0035309 \| retinopathy \| 1 C0022893 \| labyrinthitis \| 1 C0039446 \| telangiectasia \| 1 C0012739 \| disseminated intravascular coagulation \| 1 C0020877 \| ileitis \| 1 C0043092 \| wegener's granulomatosis \| 1 C0003874 \| septic arthritis \| 1 C0007113 \| carcinoma of the rectum \| 1 C0221036 \| acrodermatitis enteropathica \| 1 C0024314 \| lymphoproliferative disorder \| 1 C0005586 \| bipolar disorder \| 1 C0037274 \| skin disease \| 1 C0003872 \| psoriatic arthritis \| 1 C0021831 \| intestinal diseases \| 1 C0007115 \| thyroid ca \| 1 C0019655 \| histoplasmosis \| 1 C0002438 \| amoebiasis \| 1 C0024236 \| lymphedema \| 1 C0339962 \| pulmonary mucormycosis \| 1 C0011226 \| hepatitis d \| 1 C0014118 \| endocarditis \| 1 C0043117 \| immune thrombocytopenic purpura \| 1 C0027697 \| nephritis \| 1 C0033687 \| proteinuria \| 1 C0032587 \| polyradiculoneuropathy \| 1 C0018916 \| angioma \| 1 C0017105 \| gas gangrene \| 1 C0042769 \| virus infection \| 1 C0033680 \| protein losing enteropathy \| 1 C0036114 \| salmonellosis \| 1 C0079774 \| peripheral t-cell lymphoma \| 1 C0019196 \| hepatitis c \| 1 C0035258 \| restless legs syndrome (rls) \| 1 C0025202 \| malignant melanoma \| 1 C0024312 \| lymphopenia \| 1 C0017658 \| glomerulonephritis \| 1 C0410422 \| chronic recurrent multifocal osteomyelitis \| 1 C0022660 \| acute kidney failure \| 1 C0028242 \| nocardiosis \| 1 C0009806 \| constipation \| 1 C0027707 \| interstitial nephritis \| 1 C0039445 \| hereditary hemorrhagic telangiectasia \| 1 C0004245 \| atrioventricular block \| 1 C0027831 \| von recklinghausen disease \| 1 C0019360 \| zoster \| 1 C0006060 \| mediterranean spotted fever \| 1 C0029442 \| osteomalacia \| 1 C0017105 \| clostridial myonecrosis \| 1 C0014541 \| epiglottitis \| 1 C0011847 \| diabetes \| 1 C0549473 \| thyroid carcinoma \| 1 C0039263 \| takayasu disease \| 1 C0151436 \| leukocytoclastic vasculitis \| 1 C0025309 \| meningoencephalitis \| 1 C0005745 \| ptosis \| 1 C0041316 \| tuberculous lymphadenitis \| 1 C0025202 \| melanoma \| 1 C0026393 \| molluscum contagiosum \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:102) HLA-DRB1 \| 3123 \| CTD_human TNF \| 7124 \| CTD_human;GWASCAT IL6 \| 3569 \| CTD_human BACH2 \| 60468 \| CTD_human;GWASCAT STAT3 \| 6774 \| GWASCAT GPR65 \| 8477 \| GWASCAT SMAD3 \| 4088 \| CTD_human;GWASCAT IFNG \| 3458 \| CTD_human LEP \| 3952 \| CTD_human ADIPOQ \| 9370 \| CTD_human NOD2 \| 64127 \| CTD_human;GWASCAT;GHR CRP \| 1401 \| CTD_human DNMT3A \| 1788 \| CTD_human;GWASCAT CCL2 \| 6347 \| CTD_human THADA \| 63892 \| GWASCAT PPARA \| 5465 \| CTD_human C1orf106 \| 55765 \| GWASCAT CLN3 \| 1201 \| GWASCAT SOCS1 \| 8651 \| GWASCAT BTNL2 \| 56244 \| GWASCAT C21orf33 \| 8209 \| GWASCAT PHTF1 \| 10745 \| GWASCAT IL12B \| 3593 \| CTD_human TYK2 \| 7297 \| CTD_human;GWASCAT PTPN22 \| 26191 \| GWASCAT UBE2L3 \| 7332 \| GWASCAT NR1H4 \| 9971 \| CTD_human PHOX2B \| 8929 \| CTD_human GCKR \| 2646 \| GWASCAT ANKRD55 \| 79722 \| GWASCAT MST1 \| 4485 \| CTD_human;GWASCAT IL23R \| 149233 \| CTD_human;GWASCAT;GHR IL2RA \| 3559 \| CTD_human;GWASCAT FGFR1OP \| 11116 \| GWASCAT BANK1 \| 55024 \| GWASCAT IGF1 \| 3479 \| CTD_human IL10 \| 3586 \| CTD_human PPARG \| 5468 \| CTD_human SP140 \| 11262 \| GWASCAT NLRP3 \| 114548 \| CTD_human CCNY \| 219771 \| CTD_human;GWASCAT FUT2 \| 2524 \| CTD_human;GWASCAT SLC11A1 \| 6556 \| CTD_human PSMB10 \| 5699 \| GWASCAT ZGPAT \| 84619 \| GWASCAT SBSPON \| 157869 \| GWASCAT TAGAP \| 117289 \| CTD_human LACC1 \| 144811 \| GWASCAT PPP5C \| 5536 \| GWASCAT C5orf56 \| 441108 \| GWASCAT PTPN2 \| 5771 \| CTD_human;GWASCAT TLR4 \| 7099 \| CTD_human LTA \| 4049 \| GWASCAT SLC22A23 \| 63027 \| GWASCAT CPEB4 \| 80315 \| GWASCAT NCF4 \| 4689 \| CTD_human TMEM258 \| 746 \| GWASCAT ITLN1 \| 55600 \| GWASCAT ZNF365 \| 22891 \| GWASCAT IRGM \| 345611 \| CTD_human;GHR DENND1B \| 163486 \| CTD_human;GWASCAT PSORS1C3 \| 100130889 \| GWASCAT FAM92B \| 339145 \| CTD_human PTRF \| 284119 \| GWASCAT VTN \| 7448 \| CTD_human C1orf141 \| 400757 \| GWASCAT PUS10 \| 150962 \| GWASCAT JAZF1 \| 221895 \| GWASCAT CD244 \| 51744 \| GWASCAT ATG16L1 \| 55054 \| CTD_human;GWASCAT;GHR GPBAR1 \| 151306 \| CTD_human MLN \| 4295 \| GWASCAT NKX2-3 \| 159296 \| CTD_human;GWASCAT ZMIZ1 \| 57178 \| GWASCAT PER3 \| 8863 \| GWASCAT ERAP2 \| 64167 \| CTD_human;GWASCAT TNFSF15 \| 9966 \| GWASCAT SCAMP3 \| 10067 \| GWASCAT CARD9 \| 64170 \| GWASCAT BSN \| 8927 \| GWASCAT IFNGR2 \| 3460 \| GWASCAT FN1 \| 2335 \| CTD_human SKAP2 \| 8935 \| GWASCAT TLR9 \| 54106 \| CTD_human MUC19 \| 283463 \| GWASCAT ELF1 \| 1997 \| GWASCAT IL18RAP \| 8807 \| GWASCAT LINC00492 \| 100861468 \| GWASCAT CLCA2 \| 9635 \| GWASCAT CDKAL1 \| 54901 \| GWASCAT SLAIN2 \| 57606 \| GWASCAT LINC01475 \| 101927324 \| GWASCAT KSR1 \| 8844 \| GWASCAT SCARNA5 \| 677775 \| GWASCAT RSPO3 \| 84870 \| GWASCAT FCHSD2 \| 9873 \| GWASCAT MAGI1 \| 9223 \| GWASCAT FPR2 \| 2358 \| CTD_human SBNO2 \| 22904 \| GWASCAT MROH3P \| 647215 \| GWASCAT TMEM17 \| 200728 \| GWASCAT RNASET2 \| 8635 \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:150) 5243 \| ABCB1 \| infer 55054 \| ATG16L1 \| infer 10678 \| B3GNT2 \| infer 60468 \| BACH2 \| infer 91272 \| BOD1 \| infer 8927 \| BSN \| infer 256815 \| C10orf67 \| infer 8209 \| C21orf33 \| infer 441108 \| C5orf56 \| infer 100130988 \| C7orf72 \| infer 64170 \| CARD9 \| infer 842 \| CASP9 \| infer 6347 \| CCL2 \| infer 54901 \| CDKAL1 \| infer 1201 \| CLN3 \| infer 26047 \| CNTNAP2 \| infer 1601 \| DAB2 \| infer 1672 \| DEFB1 \| infer 163486 \| DENND1B \| infer 9231 \| DLG5 \| infer 1788 \| DNMT3A \| infer 64167 \| ERAP2 \| infer 56677 \| FABP3P2 \| infer 356 \| FASLG \| infer 2214 \| FCGR3A \| infer 11116 \| FGFR1OP \| infer 2524 \| FUT2 \| infer 2646 \| GCKR \| infer 2805 \| GOT1 \| infer 8477 \| GPR65 \| infer 3119 \| HLA-DQB1 \| infer 50941 \| IBD5 \| infer 340198 \| IFITM4P \| infer 3500 \| IGHG1 \| infer 3586 \| IL10 \| infer 3593 \| IL12B \| infer 8807 \| IL18RAP \| infer 149233 \| IL23R \| infer 3559 \| IL2RA \| infer 3562 \| IL3 \| infer 3569 \| IL6 \| infer 345611 \| IRGM \| infer 55600 \| ITLN1 \| infer 1316 \| KLF6 \| infer 134008 \| MRPL11P2 \| infer 359779 \| MRPS35P3 \| infer 4485 \| MST1 \| infer 4524 \| MTHFR \| infer 4548 \| MTR \| infer 4552 \| MTRR \| infer 4650 \| MYO9B \| infer 4745 \| NELL1 \| infer 79576 \| NKAP \| infer 159296 \| NKX2-3 \| infer 10392 \| NOD1 \| infer 64127 \| NOD2 \| infer 2908 \| NR3C1 \| infer 8204 \| NRIP1 \| infer 5155 \| PDGFB \| infer 8863 \| PER3 \| infer 5334 \| PLCL1 \| infer 5468 \| PPARG \| infer 25824 \| PRDX5 \| infer 5699 \| PSMB10 \| infer 56984 \| PSMG2 \| infer 26191 \| PTPN22 \| infer 150962 \| PUS10 \| infer 5820 \| PVT1 \| infer 10171 \| RCL1 \| infer 326275 \| RPL12P7 \| infer 100271305 \| RPL30P13 \| infer 728010 \| RPL35P3 \| infer 100271352 \| RPS12P16 \| infer 100271063 \| RPS14P1 \| infer 100271600 \| RPS3AP51 \| infer 6304 \| SATB1 \| infer 10067 \| SCAMP3 \| infer 63027 \| SLC22A23 \| infer 6583 \| SLC22A4 \| infer 6584 \| SLC22A5 \| infer 29015 \| SLC43A3 \| infer 56301 \| SLC7A10 \| infer 133482 \| SLCO6A1 \| infer 4088 \| SMAD3 \| infer 11262 \| SP140 \| infer 6774 \| STAT3 \| infer 117289 \| TAGAP \| infer 256536 \| TCERG1L \| infer 63892 \| THADA \| infer 134288 \| TMEM174 \| infer 7124 \| TNF \| infer 7132 \| TNFRSF1A \| infer 7133 \| TNFRSF1B \| infer 9966 \| TNFSF15 \| infer 10221 \| TRIB1 \| infer 7297 \| TYK2 \| infer 7332 \| UBE2L3 \| infer 84619 \| ZGPAT \| infer 57178 \| ZMIZ1 \| infer 22891 \| ZNF365 \| infer 124626 \| ZPBP2 \| infer 219771 \| CCNY \| infer 5771 \| PTPN2 \| infer 729230 \| CCR2 \| infer 1234 \| CCR5 \| infer 1235 \| CCR6 \| infer 929 \| CD14 \| infer 930 \| CD19 \| infer 1401 \| CRP \| infer 1436 \| CSF1R \| infer 1543 \| CYP1A1 \| infer 2052 \| EPHX1 \| infer 2944 \| GSTM1 \| infer 2950 \| GSTP1 \| infer 2952 \| GSTT1 \| infer 3106 \| HLA-B \| infer 3122 \| HLA-DRA \| infer 3123 \| HLA-DRB1 \| infer 3304 \| HSPA1B \| infer 3306 \| HSPA2 \| infer 3383 \| ICAM1 \| infer 23308 \| ICOSLG \| infer 3603 \| IL16 \| infer 3606 \| IL18 \| infer 3554 \| IL1R1 \| infer 3565 \| IL4 \| infer 3566 \| IL4R \| infer 3659 \| IRF1 \| infer 3717 \| JAK2 \| infer 120892 \| LRRK2 \| infer 4049 \| LTA \| infer 4153 \| MBL2 \| infer 4282 \| MIF \| infer 283463 \| MUC19 \| infer 4790 \| NFKB1 \| infer 4792 \| NFKBIA \| infer 94103 \| ORMDL3 \| infer 5027 \| P2RX7 \| infer 8974 \| P4HA2 \| infer 9124 \| PDLIM1 \| infer 170679 \| PSORS1C1 \| infer 5734 \| PTGER4 \| infer 5054 \| SERPINE1 \| infer 6556 \| SLC11A1 \| infer 7097 \| TLR2 \| infer 7099 \| TLR4 \| infer 54106 \| TLR9 \| infer 7172 \| TPMT \| infer 7421 \| VDR \| infer 1610 \| DAO \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:757) 100419743 \| DBET \| DISEASES 2288 \| FKBP4 \| DISEASES 6542 \| SLC7A2 \| DISEASES 10344 \| CCL26 \| DISEASES 6376 \| CX3CL1 \| DISEASES 8993 \| PGLYRP1 \| DISEASES 920 \| CD4 \| DISEASES 3385 \| ICAM3 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 602 \| BCL3 \| DISEASES 8974 \| P4HA2 \| DISEASES 6694 \| SPP2 \| DISEASES 3566 \| IL4R \| DISEASES 6343 \| SCT \| DISEASES 30009 \| TBX21 \| DISEASES 1361 \| CPB2 \| DISEASES 4680 \| CEACAM6 \| DISEASES 6583 \| SLC22A4 \| DISEASES 6583 \| SLC22A4 \| DISEASES 1725 \| DHPS \| DISEASES 8174 \| MADCAM1 \| DISEASES 4282 \| MIF \| DISEASES 6948 \| TCN2 \| DISEASES 3956 \| LGALS1 \| DISEASES 7494 \| XBP1 \| DISEASES 3162 \| HMOX1 \| DISEASES 158 \| ADSL \| DISEASES 11035 \| RIPK3 \| DISEASES 1511 \| CTSG \| DISEASES 3002 \| GZMB \| DISEASES 4792 \| NFKBIA \| DISEASES 3929 \| LBP \| DISEASES 7076 \| TIMP1 \| DISEASES 479 \| ATP12A \| DISEASES 54602 \| NDFIP2 \| DISEASES 2862 \| MLNR \| DISEASES 4313 \| MMP2 \| DISEASES 4210 \| MEFV \| DISEASES 343 \| AQP8 \| DISEASES 55192 \| DNAJC17 \| DISEASES 8767 \| RIPK2 \| DISEASES 10404 \| CPQ \| DISEASES 8797 \| TNFRSF10A \| DISEASES 4051 \| CYP4F3 \| DISEASES 56729 \| RETN \| DISEASES 7040 \| TGFB1 \| DISEASES 973 \| CD79A \| DISEASES 1048 \| CEACAM5 \| DISEASES 57817 \| HAMP \| DISEASES 10061 \| ABCF2 \| DISEASES 3912 \| LAMB1 \| DISEASES 10392 \| NOD1 \| DISEASES 10392 \| NOD1 \| DISEASES 6369 \| CCL24 \| DISEASES 5054 \| SERPINE1 \| DISEASES 944 \| TNFSF8 \| DISEASES 6348 \| CCL3 \| DISEASES 4353 \| MPO \| DISEASES 8288 \| EPX \| DISEASES 1440 \| CSF3 \| DISEASES 6347 \| CCL2 \| DISEASES 6357 \| CCL13 \| DISEASES 1277 \| COL1A1 \| DISEASES 7448 \| VTN \| DISEASES 6372 \| CXCL6 \| DISEASES 8929 \| PHOX2B \| DISEASES 4790 \| NFKB1 \| DISEASES 3558 \| IL2 \| DISEASES 24145 \| PANX1 \| DISEASES 3587 \| IL10RA \| DISEASES 969 \| CD69 \| DISEASES 51561 \| IL23A \| DISEASES 55801 \| IL26 \| DISEASES 3458 \| IFNG \| DISEASES 3820 \| KLRB1 \| DISEASES 1432 \| MAPK14 \| DISEASES 2690 \| GHR \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 2908 \| NR3C1 \| DISEASES 6556 \| SLC11A1 \| DISEASES 92840 \| REEP6 \| DISEASES 5967 \| REG1A \| DISEASES 3488 \| IGFBP5 \| DISEASES 4759 \| NEU2 \| DISEASES 3554 \| IL1R1 \| DISEASES 8809 \| IL18R1 \| DISEASES 566 \| AZU1 \| DISEASES 5657 \| PRTN3 \| DISEASES 9528 \| TMEM59 \| DISEASES 11126 \| CD160 \| DISEASES 6402 \| SELL \| DISEASES 7276 \| TTR \| DISEASES 7128 \| TNFAIP3 \| DISEASES 80306 \| MED28 \| DISEASES 23307 \| FKBP15 \| DISEASES 54812 \| AFTPH \| DISEASES 4360 \| MRC1 \| DISEASES 8600 \| TNFSF11 \| DISEASES 4852 \| NPY \| DISEASES 35 \| ACADS \| DISEASES 7130 \| TNFAIP6 \| DISEASES 5266 \| PI3 \| DISEASES 27189 \| IL17C \| DISEASES 54210 \| TREM1 \| DISEASES 4502 \| MT2A \| DISEASES 6555 \| SLC10A2 \| DISEASES 6584 \| SLC22A5 \| DISEASES 6584 \| SLC22A5 \| DISEASES 3659 \| IRF1 \| DISEASES 30833 \| NT5C \| DISEASES 718 \| C3 \| DISEASES 1236 \| CCR7 \| DISEASES 3306 \| HSPA2 \| DISEASES 7429 \| VIL1 \| DISEASES 2952 \| GSTT1 \| DISEASES 968 \| CD68 \| DISEASES 6351 \| CCL4 \| DISEASES 1215 \| CMA1 \| DISEASES 9459 \| ARHGEF6 \| DISEASES 3630 \| INS \| DISEASES 120400 \| NXPE1 \| DISEASES 9945 \| GFPT2 \| DISEASES 6382 \| SDC1 \| DISEASES 1401 \| CRP \| DISEASES 8546 \| AP3B1 \| DISEASES 1116 \| CHI3L1 \| DISEASES 3845 \| KRAS \| DISEASES 759 \| CA1 \| DISEASES 27299 \| ADAMDEC1 \| DISEASES 83998 \| REG4 \| DISEASES 60468 \| BACH2 \| DISEASES 4907 \| NT5E \| DISEASES 9038 \| TAAR5 \| DISEASES 80896 \| NPL \| DISEASES 80896 \| NPL \| DISEASES 55270 \| NUDT15 \| DISEASES 3569 \| IL6 \| DISEASES 10241 \| CALCOCO2 \| DISEASES 3557 \| IL1RN \| DISEASES 26525 \| IL36RN \| DISEASES 6366 \| CCL21 \| DISEASES 10850 \| CCL27 \| DISEASES 7097 \| TLR2 \| DISEASES 10068 \| IL18BP \| DISEASES 4316 \| MMP7 \| DISEASES 2984 \| GUCY2C \| DISEASES 11213 \| IRAK3 \| DISEASES 4069 \| LYZ \| DISEASES 23359 \| FAM189A1 \| DISEASES 29121 \| CLEC2D \| DISEASES 7450 \| VWF \| DISEASES 7188 \| TRAF5 \| DISEASES 51444 \| RNF138 \| DISEASES 999 \| CDH1 \| DISEASES 54825 \| CDHR2 \| DISEASES 4092 \| SMAD7 \| DISEASES 4087 \| SMAD2 \| DISEASES 945 \| CD33 \| DISEASES 3595 \| IL12RB2 \| DISEASES 9618 \| TRAF4 \| DISEASES 9739 \| SETD1A \| DISEASES 495 \| ATP4A \| DISEASES 23031 \| MAST3 \| DISEASES 671 \| BPI \| DISEASES 25939 \| SAMHD1 \| DISEASES 3783 \| KCNN4 \| DISEASES 5595 \| MAPK3 \| DISEASES 1326 \| MAP3K8 \| DISEASES 3682 \| ITGAE \| DISEASES 1 \| A1BG \| DISEASES 23523 \| CABIN1 \| DISEASES 55686 \| MREG \| DISEASES 27178 \| IL37 \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 9466 \| IL27RA \| DISEASES 54776 \| PPP1R12C \| DISEASES 1991 \| ELANE \| DISEASES 6403 \| SELP \| DISEASES 3574 \| IL7 \| DISEASES 943 \| TNFRSF8 \| DISEASES 4162 \| MCAM \| DISEASES 3938 \| LCT \| DISEASES 8540 \| AGPS \| DISEASES 941 \| CD80 \| DISEASES 59067 \| IL21 \| DISEASES 2247 \| FGF2 \| DISEASES 84162 \| KIAA1109 \| DISEASES 3589 \| IL11 \| DISEASES 3589 \| IL11 \| DISEASES 6774 \| STAT3 \| DISEASES 5443 \| POMC \| DISEASES 7297 \| TYK2 \| DISEASES 3383 \| ICAM1 \| DISEASES 7535 \| ZAP70 \| DISEASES 3827 \| KNG1 \| DISEASES 7416 \| VDAC1 \| DISEASES 5243 \| ABCB1 \| DISEASES 11234 \| HPS5 \| DISEASES 7078 \| TIMP3 \| DISEASES 939 \| CD27 \| DISEASES 55089 \| SLC38A4 \| DISEASES 3695 \| ITGB7 \| DISEASES 8477 \| GPR65 \| DISEASES 2252 \| FGF7 \| DISEASES 3687 \| ITGAX \| DISEASES 10261 \| IGSF6 \| DISEASES 3394 \| IRF8 \| DISEASES 54849 \| DEF8 \| DISEASES 6687 \| SPG7 \| DISEASES 7157 \| TP53 \| DISEASES 6455 \| SH3GL1 \| DISEASES 207 \| AKT1 \| DISEASES 2212 \| FCGR2A \| DISEASES 52 \| ACP1 \| DISEASES 8446 \| DUSP11 \| DISEASES 26154 \| ABCA12 \| DISEASES 2169 \| FABP2 \| DISEASES 54901 \| CDKAL1 \| DISEASES 222663 \| SCUBE3 \| DISEASES 2768 \| GNA12 \| DISEASES 7552 \| ZNF711 \| DISEASES 3934 \| LCN2 \| DISEASES 133 \| ADM \| DISEASES 6768 \| ST14 \| DISEASES 3606 \| IL18 \| DISEASES 112936 \| VPS26B \| DISEASES 7082 \| TJP1 \| DISEASES 7292 \| TNFSF4 \| DISEASES 5741 \| PTH \| DISEASES 23643 \| LY96 \| DISEASES 760 \| CA2 \| DISEASES 29761 \| USP25 \| DISEASES 10 \| NAT2 \| DISEASES 10538 \| BATF \| DISEASES 9073 \| CLDN8 \| DISEASES 6750 \| SST \| DISEASES 5468 \| PPARG \| DISEASES 3815 \| KIT \| DISEASES 171586 \| ABHD3 \| DISEASES 909 \| CD1A \| DISEASES 50848 \| F11R \| DISEASES 3588 \| IL10RB \| DISEASES 6781 \| STC1 \| DISEASES 114771 \| PGLYRP3 \| DISEASES 1636 \| ACE \| DISEASES 5681 \| PSKH1 \| DISEASES 7032 \| TFF2 \| DISEASES 7031 \| TFF1 \| DISEASES 2220 \| FCN2 \| DISEASES 729230 \| CCR2 \| DISEASES 1234 \| CCR5 \| DISEASES 221914 \| GPC2 \| DISEASES 150223 \| YDJC \| DISEASES 114757 \| CYGB \| DISEASES 6352 \| CCL5 \| DISEASES 6777 \| STAT5B \| DISEASES 1990 \| CELA1 \| DISEASES 58191 \| CXCL16 \| DISEASES 9965 \| FGF19 \| DISEASES 7412 \| VCAM1 \| DISEASES 2215 \| FCGR3B \| DISEASES 5966 \| REL \| DISEASES 151354 \| FAM84A \| DISEASES 27306 \| HPGDS \| DISEASES 84666 \| RETNLB \| DISEASES 213 \| ALB \| DISEASES 2921 \| CXCL3 \| DISEASES 6374 \| CXCL5 \| DISEASES 5473 \| PPBP \| DISEASES 5196 \| PF4 \| DISEASES 84343 \| HPS3 \| DISEASES 7349 \| UCN \| DISEASES 4486 \| MST1R \| DISEASES 308 \| ANXA5 \| DISEASES 132612 \| ADAD1 \| DISEASES 3600 \| IL15 \| DISEASES 51752 \| ERAP1 \| DISEASES 7098 \| TLR3 \| DISEASES 1437 \| CSF2 \| DISEASES 116379 \| IL22RA2 \| DISEASES 221955 \| DAGLB \| DISEASES 10569 \| SLU7 \| DISEASES 54882 \| ANKHD1 \| DISEASES 4982 \| TNFRSF11B \| DISEASES 1671 \| DEFA6 \| DISEASES 1672 \| DEFB1 \| DISEASES 157724 \| SLC7A13 \| DISEASES 79937 \| CNTNAP3 \| DISEASES 4783 \| NFIL3 \| DISEASES 283209 \| PGM2L1 \| DISEASES 5267 \| SERPINA4 \| DISEASES 120892 \| LRRK2 \| DISEASES 79803 \| HPS6 \| DISEASES 79158 \| GNPTAB \| DISEASES 5896 \| RAG1 \| DISEASES 338339 \| CLEC4D \| DISEASES 4314 \| MMP3 \| DISEASES 290 \| ANPEP \| DISEASES 6778 \| STAT6 \| DISEASES 6778 \| STAT6 \| DISEASES 5245 \| PHB \| DISEASES 64127 \| NOD2 \| DISEASES 64127 \| NOD2 \| DISEASES 4218 \| RAB8A \| DISEASES 353514 \| LILRA5 \| DISEASES 3816 \| KLK1 \| DISEASES 284110 \| GSDMA \| DISEASES 956 \| ENTPD3 \| DISEASES 474 \| ATOH1 \| DISEASES 6356 \| CCL11 \| DISEASES 6037 \| RNASE3 \| DISEASES 116844 \| LRG1 \| DISEASES 3479 \| IGF1 \| DISEASES 5734 \| PTGER4 \| DISEASES 3603 \| IL16 \| DISEASES 3308 \| HSPA4 \| DISEASES 5968 \| REG1B \| DISEASES 6869 \| TACR1 \| DISEASES 1673 \| DEFB4A \| DISEASES 1673 \| DEFB4A \| DISEASES 1493 \| CTLA4 \| DISEASES 5068 \| REG3A \| DISEASES 10663 \| CXCR6 \| DISEASES 94103 \| ORMDL3 \| DISEASES 3596 \| IL13 \| DISEASES 1901 \| S1PR1 \| DISEASES 3627 \| CXCL10 \| DISEASES 3575 \| IL7R \| DISEASES 2353 \| FOS \| DISEASES 56246 \| MRAP \| DISEASES 654483 \| BOLA2B \| DISEASES 6373 \| CXCL11 \| DISEASES 27087 \| B3GAT1 \| DISEASES 140886 \| PABPC5 \| DISEASES 197259 \| MLKL \| DISEASES 2147 \| F2 \| DISEASES 5897 \| RAG2 \| DISEASES 1540 \| CYLD \| DISEASES 5340 \| PLG \| DISEASES 171389 \| NLRP6 \| DISEASES 116535 \| MRGPRF \| DISEASES 3265 \| HRAS \| DISEASES 6868 \| ADAM17 \| DISEASES 947 \| CD34 \| DISEASES 3310 \| HSPA6 \| DISEASES 836 \| CASP3 \| DISEASES 6578 \| SLCO2A1 \| DISEASES 1521 \| CTSW \| DISEASES 84971 \| ATG4D \| DISEASES 5771 \| PTPN2 \| DISEASES 5319 \| PLA2G1B \| DISEASES 7172 \| TPMT \| DISEASES 201625 \| DNAH12 \| DISEASES 3952 \| LEP \| DISEASES 54472 \| TOLLIP \| DISEASES 30835 \| CD209 \| DISEASES 57217 \| TTC7A \| DISEASES 144811 \| LACC1 \| DISEASES 9377 \| COX5A \| DISEASES 2529 \| FUT7 \| DISEASES 89872 \| AQP10 \| DISEASES 260436 \| FDCSP \| DISEASES 4684 \| NCAM1 \| DISEASES 8630 \| HSD17B6 \| DISEASES 54984 \| PINX1 \| DISEASES 3579 \| CXCR2 \| DISEASES 9120 \| SLC16A6 \| DISEASES 80381 \| CD276 \| DISEASES 9370 \| ADIPOQ \| DISEASES 140596 \| DEFB104A \| DISEASES 90933 \| TRIM41 \| DISEASES 23765 \| IL17RA \| DISEASES 414325 \| DEFB103A \| DISEASES 6863 \| TAC1 \| DISEASES 149233 \| IL23R \| DISEASES 256815 \| C10orf67 \| DISEASES 503618 \| DEFB104B \| DISEASES 3039 \| HBA1 \| DISEASES 246330 \| PELI3 \| DISEASES 4312 \| MMP1 \| DISEASES 153562 \| MARVELD2 \| DISEASES 55600 \| ITLN1 \| DISEASES 8408 \| ULK1 \| DISEASES 55894 \| DEFB103B \| DISEASES 9235 \| IL32 \| DISEASES 4584 \| MUC3A \| DISEASES 940 \| CD28 \| DISEASES 150962 \| PUS10 \| DISEASES 9622 \| KLK4 \| DISEASES 89849 \| ATG16L2 \| DISEASES 6097 \| RORC \| DISEASES 4094 \| MAF \| DISEASES 146722 \| CD300LF \| DISEASES 4843 \| NOS2 \| DISEASES 1435 \| CSF1 \| DISEASES 3563 \| IL3RA \| DISEASES 10293 \| TRAIP \| DISEASES 8784 \| TNFRSF18 \| DISEASES 1668 \| DEFA3 \| DISEASES 23046 \| KIF21B \| DISEASES 50616 \| IL22 \| DISEASES 8651 \| SOCS1 \| DISEASES 1670 \| DEFA5 \| DISEASES 8624 \| PSMG1 \| DISEASES 9121 \| SLC16A5 \| DISEASES 9021 \| SOCS3 \| DISEASES 54014 \| BRWD1 \| DISEASES 8519 \| IFITM1 \| DISEASES 7850 \| IL1R2 \| DISEASES 552900 \| BOLA2 \| DISEASES 2520 \| GAST \| DISEASES 6401 \| SELE \| DISEASES 942 \| CD86 \| DISEASES 124460 \| SNX20 \| DISEASES 4088 \| SMAD3 \| DISEASES 3916 \| LAMP1 \| DISEASES 682 \| BSG \| DISEASES 51363 \| CHST15 \| DISEASES 2152 \| F3 \| DISEASES 57178 \| ZMIZ1 \| DISEASES 51738 \| GHRL \| DISEASES 124626 \| ZPBP2 \| DISEASES 8856 \| NR1I2 \| DISEASES 9075 \| CLDN2 \| DISEASES 1103 \| CHAT \| DISEASES 114548 \| NLRP3 \| DISEASES 55795 \| PCID2 \| DISEASES 112744 \| IL17F \| DISEASES 1576 \| CYP3A4 \| DISEASES 89781 \| HPS4 \| DISEASES 23583 \| SMUG1 \| DISEASES 3266 \| ERAS \| DISEASES 2309 \| FOXO3 \| DISEASES 85480 \| TSLP \| DISEASES 3329 \| HSPD1 \| DISEASES 7100 \| TLR5 \| DISEASES 6776 \| STAT5A \| DISEASES 84639 \| IL1F10 \| DISEASES 3804 \| KIR2DL3 \| DISEASES 1364 \| CLDN4 \| DISEASES 400935 \| IL17REL \| DISEASES 921 \| CD5 \| DISEASES 159296 \| NKX2-3 \| DISEASES 29949 \| IL19 \| DISEASES 3716 \| JAK1 \| DISEASES 9474 \| ATG5 \| DISEASES 3836 \| KPNA1 \| DISEASES 3605 \| IL17A \| DISEASES 7332 \| UBE2L3 \| DISEASES 1499 \| CTNNB1 \| DISEASES 199953 \| TMEM201 \| DISEASES 729967 \| MORN2 \| DISEASES 1861 \| TOR1A \| DISEASES 114770 \| PGLYRP2 \| DISEASES 9863 \| MAGI2 \| DISEASES 10533 \| ATG7 \| DISEASES 65251 \| ZNF649 \| DISEASES 100506658 \| OCLN \| DISEASES 79710 \| MORC4 \| DISEASES 331 \| XIAP \| DISEASES 355 \| FAS \| DISEASES 4698 \| NDUFA5 \| DISEASES 5265 \| SERPINA1 \| DISEASES 3240 \| HP \| DISEASES 3841 \| KPNA5 \| DISEASES 3476 \| IGBP1 \| DISEASES 5284 \| PIGR \| DISEASES 6288 \| SAA1 \| DISEASES 1822 \| ATN1 \| DISEASES 64116 \| SLC39A8 \| DISEASES 283234 \| CCDC88B \| DISEASES 10124 \| ARL4A \| DISEASES 3683 \| ITGAL \| DISEASES 5725 \| PTBP1 \| DISEASES 987 \| LRBA \| DISEASES 4745 \| NELL1 \| DISEASES 3663 \| IRF5 \| DISEASES 10807 \| SDCCAG3 \| DISEASES 5802 \| PTPRS \| DISEASES 60 \| ACTB \| DISEASES 10803 \| CCR9 \| DISEASES 1524 \| CX3CR1 \| DISEASES 6775 \| STAT4 \| DISEASES 841 \| CASP8 \| DISEASES 2526 \| FUT4 \| DISEASES 6364 \| CCL20 \| DISEASES 6364 \| CCL20 \| DISEASES 9332 \| CD163 \| DISEASES 5602 \| MAPK10 \| DISEASES 57115 \| PGLYRP4 \| DISEASES 26191 \| PTPN22 \| DISEASES 387129 \| NPSR1 \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 5697 \| PYY \| DISEASES 7037 \| TFRC \| DISEASES 4638 \| MYLK \| DISEASES 55876 \| GSDMB \| DISEASES 3135 \| HLA-G \| DISEASES 5599 \| MAPK8 \| DISEASES 54106 \| TLR9 \| DISEASES 2530 \| FUT8 \| DISEASES 58484 \| NLRC4 \| DISEASES 2673 \| GFPT1 \| DISEASES 6772 \| STAT1 \| DISEASES 22904 \| SBNO2 \| DISEASES 9181 \| ARHGEF2 \| DISEASES 4283 \| CXCL9 \| DISEASES 7096 \| TLR1 \| DISEASES 7052 \| TGM2 \| DISEASES 7042 \| TGFB2 \| DISEASES 6580 \| SLC22A1 \| DISEASES 25936 \| NSL1 \| DISEASES 117289 \| TAGAP \| DISEASES 92703 \| TMEM183A \| DISEASES 7432 \| VIP \| DISEASES 55765 \| C1orf106 \| DISEASES 5788 \| PTPRC \| DISEASES 5743 \| PTGS2 \| DISEASES 4688 \| NCF2 \| DISEASES 58527 \| ABRACL \| DISEASES 462 \| SERPINC1 \| DISEASES 356 \| FASLG \| DISEASES 2214 \| FCGR3A \| DISEASES 1490 \| CTGF \| DISEASES 910 \| CD1B \| DISEASES 911 \| CD1C \| DISEASES 115352 \| FCRL3 \| DISEASES 632 \| BGLAP \| DISEASES 3570 \| IL6R \| DISEASES 7170 \| TPM3 \| DISEASES 441168 \| FAM26F \| DISEASES 256536 \| TCERG1L \| DISEASES 6283 \| S100A12 \| DISEASES 6280 \| S100A9 \| DISEASES 4014 \| LOR \| DISEASES 10758 \| TRAF3IP2 \| DISEASES 262 \| AMD1 \| DISEASES 50624 \| CUZD1 \| DISEASES 1755 \| DMBT1 \| DISEASES 1893 \| ECM1 \| DISEASES 639 \| PRDM1 \| DISEASES 2209 \| FCGR1A \| DISEASES 2209 \| FCGR1A \| DISEASES 11085 \| ADAM30 \| DISEASES 58528 \| RRAGD \| DISEASES 914 \| CD2 \| DISEASES 8517 \| IKBKG \| DISEASES 3738 \| KCNA3 \| DISEASES 8771 \| TNFRSF6B \| DISEASES 84795 \| PYROXD2 \| DISEASES 959 \| CD40LG \| DISEASES 112817 \| HOGA1 \| DISEASES 84251 \| SGIP1 \| DISEASES 55225 \| RAVER2 \| DISEASES 5236 \| PGM1 \| DISEASES 1791 \| DNTT \| DISEASES 953 \| ENTPD1 \| DISEASES 3725 \| JUN \| DISEASES 64170 \| CARD9 \| DISEASES 7422 \| VEGFA \| DISEASES 115201 \| ATG4A \| DISEASES 958 \| CD40 \| DISEASES 4318 \| MMP9 \| DISEASES 9231 \| DLG5 \| DISEASES 9231 \| DLG5 \| DISEASES 2491 \| CENPI \| DISEASES 27035 \| NOX1 \| DISEASES 9436 \| NCR2 \| DISEASES 6865 \| TACR2 \| DISEASES 2833 \| CXCR3 \| DISEASES 54952 \| TRNAU1AP \| DISEASES 4153 \| MBL2 \| DISEASES 7099 \| TLR4 \| DISEASES 9966 \| TNFSF15 \| DISEASES 143162 \| FRMPD2 \| DISEASES 219771 \| CCNY \| DISEASES 56288 \| PARD3 \| DISEASES 5535 \| PPP3R2 \| DISEASES 3118 \| HLA-DQA2 \| DISEASES 5320 \| PLA2G2A \| DISEASES 30814 \| PLA2G2E \| DISEASES 23252 \| OTUD3 \| DISEASES 54546 \| RNF186 \| DISEASES 23569 \| PADI4 \| DISEASES 3055 \| HCK \| DISEASES 4795 \| NFKBIL1 \| DISEASES 50943 \| FOXP3 \| DISEASES 100507436 \| MICA \| DISEASES 100507436 \| MICA \| DISEASES 3107 \| HLA-C \| DISEASES 7133 \| TNFRSF1B \| DISEASES 6564 \| SLC15A1 \| DISEASES 4524 \| MTHFR \| DISEASES 11074 \| TRIM31 \| DISEASES 3105 \| HLA-A \| DISEASES 7056 \| THBD \| DISEASES 81696 \| OR5V1 \| DISEASES 23130 \| ATG2A \| DISEASES 51160 \| VPS28 \| DISEASES 8718 \| TNFRSF25 \| DISEASES 6520 \| SLC3A2 \| DISEASES 100505591 \| LRRC3C \| DISEASES 51131 \| PHF11 \| DISEASES 414062 \| CCL3L3 \| DISEASES 9445 \| ITM2B \| DISEASES 1536 \| CYBB \| DISEASES 1114 \| CHGB \| DISEASES 9308 \| CD83 \| DISEASES 2625 \| GATA3 \| DISEASES 11193 \| WBP4 \| DISEASES 387755 \| INSC \| DISEASES 23586 \| DDX58 \| DISEASES 3559 \| IL2RA \| DISEASES 3704 \| ITPA \| DISEASES 3456 \| IFNB1 \| DISEASES 9960 \| USP3 \| DISEASES 56265 \| CPXM1 \| DISEASES 51284 \| TLR7 \| DISEASES 25849 \| PARM1 \| DISEASES 3662 \| IRF4 \| DISEASES 1045 \| CDX2 \| DISEASES 3486 \| IGFBP3 \| DISEASES 2813 \| GP2 \| DISEASES 90865 \| IL33 \| DISEASES 3717 \| JAK2 \| DISEASES 10333 \| TLR6 \| DISEASES 255189 \| PLA2G4F \| DISEASES 50506 \| DUOX2 \| DISEASES 2877 \| GPX2 \| DISEASES 116534 \| MRGPRE \| DISEASES 6370 \| CCL25 \| DISEASES 2524 \| FUT2 \| DISEASES 22900 \| CARD8 \| DISEASES 11009 \| IL24 \| DISEASES 55054 \| ATG16L1 \| DISEASES 55054 \| ATG16L1 \| DISEASES 4216 \| MAP3K4 \| DISEASES 65057 \| ACD \| DISEASES 56954 \| NIT2 \| DISEASES 55773 \| TBC1D23 \| DISEASES 84299 \| MIEN1 \| DISEASES 6355 \| CCL8 \| DISEASES 6696 \| SPP1 \| DISEASES 1365 \| CLDN3 \| DISEASES 3122 \| HLA-DRA \| DISEASES 2919 \| CXCL1 \| DISEASES 6387 \| CXCL12 \| DISEASES 3174 \| HNF4G \| DISEASES 3676 \| ITGA4 \| DISEASES 4689 \| NCF4 \| DISEASES 4650 \| MYO9B \| DISEASES 594857 \| NPS \| DISEASES 3119 \| HLA-DQB1 \| DISEASES 123745 \| PLA2G4E \| DISEASES 7442 \| TRPV1 \| DISEASES 3803 \| KIR2DL2 \| DISEASES 1439 \| CSF2RB \| DISEASES 5970 \| RELA \| DISEASES 23308 \| ICOSLG \| DISEASES 221938 \| MMD2 \| DISEASES 63027 \| SLC22A23 \| DISEASES 7018 \| TF \| DISEASES 152789 \| JAKMIP1 \| DISEASES 9873 \| FCHSD2 \| DISEASES 22891 \| ZNF365 \| DISEASES 23274 \| CLEC16A \| DISEASES 9354 \| UBE4A \| DISEASES 2641 \| GCG \| DISEASES 3384 \| ICAM2 \| DISEASES 4295 \| MLN \| DISEASES 4295 \| MLN \| DISEASES 10551 \| AGR2 \| DISEASES 3718 \| JAK3 \| DISEASES 23005 \| MAPKBP1 \| DISEASES 388552 \| BLOC1S3 \| DISEASES 8399 \| PLA2G10 \| DISEASES 1438 \| CSF2RA \| DISEASES 283463 \| MUC19 \| DISEASES 100137049 \| PLA2G4B \| DISEASES 10107 \| TRIM10 \| DISEASES 91975 \| ZNF300 \| DISEASES 960 \| CD44 \| DISEASES 7124 \| TNF \| DISEASES 7124 \| TNF \| DISEASES 3106 \| HLA-B \| DISEASES 64167 \| ERAP2 \| DISEASES 4615 \| MYD88 \| DISEASES 27151 \| CPAMD8 \| DISEASES 3594 \| IL12RB1 \| DISEASES 4049 \| LTA \| DISEASES 25822 \| DNAJB5 \| DISEASES 388372 \| CCL4L1 \| DISEASES 4588 \| MUC6 \| DISEASES 2876 \| GPX1 \| DISEASES 160857 \| CCDC122 \| DISEASES 6349 \| CCL3L1 \| DISEASES 1154 \| CISH \| DISEASES 204801 \| NLRP11 \| DISEASES 834 \| CASP1 \| DISEASES 4050 \| LTB \| DISEASES 3586 \| IL10 \| DISEASES 58155 \| PTBP2 \| DISEASES 3441 \| IFNA4 \| DISEASES 4485 \| MST1 \| DISEASES 4583 \| MUC2 \| DISEASES 55230 \| USP40 \| DISEASES 2859 \| GPR35 \| DISEASES 721 \| C4B \| DISEASES 10201 \| NME6 \| DISEASES 138065 \| RNF183 \| DISEASES 4585 \| MUC4 \| DISEASES 111 \| ADCY5 \| DISEASES 56244 \| BTNL2 \| DISEASES 7511 \| XPNPEP1 \| DISEASES 2638 \| GC \| DISEASES 51428 \| DDX41 \| DISEASES 8635 \| RNASET2 \| DISEASES 51079 \| NDUFA13 \| DISEASES 100289462 \| DEFB4B \| DISEASES 9140 \| ATG12 \| DISEASES 2920 \| CXCL2 \| DISEASES 345611 \| IRGM \| DISEASES 151306 \| GPBAR1 \| DISEASES 3620 \| IDO1 \| DISEASES 7033 \| TFF3 \| DISEASES 59351 \| PBOV1 \| DISEASES 10978 \| CLP1 \| DISEASES 4586 \| MUC5AC \| DISEASES 727897 \| MUC5B \| DISEASES 930 \| CD19 \| DISEASES 1232 \| CCR3 \| DISEASES 3684 \| ITGAM \| DISEASES 11331 \| PHB2 \| DISEASES 5027 \| P2RX7 \| DISEASES 339145 \| FAM92B \| DISEASES 169355 \| IDO2 \| DISEASES 7421 \| VDR \| DISEASES 7421 \| VDR \| DISEASES 8972 \| MGAM \| DISEASES 317 \| APAF1 \| DISEASES 317 \| APAF1 \| DISEASES 567 \| B2M \| DISEASES 820 \| CAMP \| DISEASES 22861 \| NLRP1 \| DISEASES 100287879 \| LINC00994 \| DISEASES 348120 \| LINC01193 \| DISEASES 404663 \| LINC01194 \| DISEASES 404744 \| NPSR1-AS1 \| DISEASES 641373 \| NRON \| DISEASES 677768 \| SCARNA13 \| DISEASES 619383 \| SCARNA9 \| DISEASES 27099 \| SND1-IT1 \| DISEASES 26810 \| SNORD41 \| DISEASES 26796 \| SNORD53 \| DISEASES 652995 \| UCA1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	39
Disease	crohn disease
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:179) HP:0010447 \| Fistula in ano \| 43 HP:0002583 \| Colitis \| 22 HP:0002664 \| Neoplasia \| 14 HP:0100279 \| Ulcerative colitis \| 13 HP:0002665 \| Lymphoma \| 10 HP:0002633 \| Vasculitis \| 9 HP:0005214 \| Bowel obstruction \| 9 HP:0030731 \| Carcinoma \| 8 HP:0000999 \| Pyoderma \| 7 HP:0001903 \| Anemia \| 7 HP:0002014 \| Diarrhea \| 6 HP:0001369 \| Arthritis \| 6 HP:0000143 \| Rectovaginal fistula \| 6 HP:0004320 \| Vaginal fistula \| 6 HP:0003765 \| Psoriasis \| 6 HP:0011034 \| Amyloid disease \| 6 HP:0002239 \| Gastrointestinal hemorrhage \| 5 HP:0002584 \| Intestinal hemorrhage \| 5 HP:0002955 \| Granulomatosis \| 5 HP:0030151 \| Cholangitis \| 5 HP:0012531 \| Pain \| 5 HP:0001733 \| Pancreatic inflammation \| 4 HP:0001735 \| Acute pancreatitis \| 4 HP:0012115 \| Liver inflammation \| 4 HP:0012089 \| Arteritis \| 4 HP:0012189 \| Hodgkin disease \| 4 HP:0000112 \| Nephropathy \| 4 HP:0002754 \| Bone infection \| 4 HP:0001909 \| Leukemia \| 4 HP:0000716 \| Depression \| 3 HP:0001045 \| Blotchy loss of skin color \| 3 HP:0001945 \| Fever \| 3 HP:0001513 \| Obesity \| 3 HP:0001370 \| Rheumatoid arthritis \| 3 HP:0004871 \| Perineal fistula \| 3 HP:0100507 \| Folate deficiency \| 3 HP:0012452 \| Restless legs \| 3 HP:0002595 \| Gastrointestinal atony \| 3 HP:0002725 \| Systemic lupus erythematosus \| 3 HP:0012378 \| Fatigue \| 3 HP:0001297 \| Cerebral vascular events \| 3 HP:0002090 \| Pneumonia \| 3 HP:0100523 \| Hepatic abscess \| 3 HP:0000939 \| Osteoporosis \| 3 HP:0002352 \| Leukoencephalopathy \| 3 HP:0002721 \| Immunodeficiency \| 3 HP:0000969 \| Dropsy \| 3 HP:0100512 \| Vitamin D deficiency \| 2 HP:0012324 \| Myeloid leukemia \| 2 HP:0005681 \| Juvenile idiopathic arthritis \| 2 HP:0000100 \| Nephrosis \| 2 HP:0100653 \| Optic neuritis \| 2 HP:0004398 \| Peptic ulcer \| 2 HP:0003003 \| Colon cancer \| 2 HP:0000739 \| Anxiety \| 2 HP:0100614 \| Muscle inflammation \| 2 HP:0001287 \| Meningitis \| 2 HP:0001081 \| Gallstones \| 2 HP:0004808 \| Acute myelogenous leukemia \| 2 HP:0002140 \| Ischemic stroke \| 2 HP:0002024 \| Intestinal malabsorption \| 2 HP:0002586 \| Peritonitis \| 2 HP:0001824 \| Weight loss \| 2 HP:0001876 \| Low blood cell count \| 2 HP:0012190 \| T cell lymphoma \| 2 HP:0012219 \| Erythema nodosum \| 2 HP:0004395 \| Malnutrition \| 2 HP:0040154 \| Hidradenitis suppurativa \| 2 HP:0012390 \| Anal fissure \| 2 HP:0002573 \| Bloody diarrhea \| 2 HP:0002242 \| Enteropathy \| 2 HP:0005263 \| Gastritis \| 2 HP:0002027 \| Abdominal pain \| 2 HP:0002576 \| Intussusception \| 2 HP:0000491 \| Corneal inflammation \| 2 HP:0004936 \| Blood clot in vein \| 2 HP:0000853 \| Goitre \| 2 HP:0002608 \| Celiac disease \| 2 HP:0001873 \| Low platelet count \| 2 HP:0001402 \| Hepatocellular carcinoma \| 2 HP:0010783 \| Erythema \| 2 HP:0001004 \| Lymphatic obstruction \| 1 HP:0002840 \| Lymphadenitis \| 1 HP:0000093 \| Proteinuria \| 1 HP:0002013 \| Emesis \| 1 HP:0002890 \| Thyroid carcinoma \| 1 HP:0000579 \| Nasolacrimal duct obstruction \| 1 HP:0000938 \| Decreased bone mineral density \| 1 HP:0000704 \| Pyorrhea \| 1 HP:0001907 \| Thromboembolic disease \| 1 HP:0000787 \| Renal calculi \| 1 HP:0000508 \| Drooping upper eyelid \| 1 HP:0002566 \| Intestinal malrotation \| 1 HP:0100607 \| Painful menstruation \| 1 HP:0000010 \| Frequent urinary tract infections \| 1 HP:0000855 \| Insulin resistance \| 1 HP:0001395 \| Hepatic fibrosis \| 1 HP:0000099 \| Glomerular nephritis \| 1 HP:0012735 \| Coughing \| 1 HP:0001510 \| Growth deficiency \| 1 HP:0012714 \| Severe hearing loss \| 1 HP:0100825 \| Inflammation of the lips \| 1 HP:0001678 \| Atrioventricular block \| 1 HP:0007302 \| Bipolar disorder \| 1 HP:0005318 \| Cerebral vasculitis \| 1 HP:0002113 \| Pulmonary infiltrates \| 1 HP:0000123 \| Nephritis \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0000720 \| Mood swings \| 1 HP:0200029 \| Cutaneous vasculitis \| 1 HP:0100764 \| Lymphangioma \| 1 HP:0001548 \| Overgrowth \| 1 HP:0012851 \| Narrowing of the colon \| 1 HP:0001888 \| Lymphocytopenia \| 1 HP:0002039 \| Anorexia \| 1 HP:0011505 \| Cystoid macular edema \| 1 HP:0002613 \| Biliary cirrhosis \| 1 HP:0002861 \| Melanoma \| 1 HP:0000365 \| Hearing impairment \| 1 HP:0001394 \| Hepatic cirrhosis \| 1 HP:0002917 \| Low blood magnesium levels \| 1 HP:0005901 \| Chronic recurrent multifocal osteomyelitis \| 1 HP:0009830 \| Peripheral neuritis \| 1 HP:0001056 \| Milia \| 1 HP:0100584 \| Endocarditis \| 1 HP:0012223 \| Ruptured spleen \| 1 HP:0001660 \| Common arterial trunk \| 1 HP:0002251 \| Hirschsprung megacolon \| 1 HP:0100665 \| Angiooedema \| 1 HP:0001061 \| Acne \| 1 HP:0001138 \| Damaged optic nerve \| 1 HP:0002018 \| Nausea \| 1 HP:0100590 \| Rectal fistula \| 1 HP:0200123 \| Chronic liver inflammation \| 1 HP:0003419 \| Low back pain \| 1 HP:0001970 \| Interstitial nephritis \| 1 HP:0002500 \| Leukoaraiosis \| 1 HP:0001890 \| Autoimmune hemolytic anemia \| 1 HP:0005211 \| Midgut malrotation \| 1 HP:0002910 \| Elevated transaminases \| 1 HP:0010280 \| Stomatitis \| 1 HP:0001298 \| Encephalopathy \| 1 HP:0012538 \| Gluten sensitivity \| 1 HP:0004349 \| Reduced bone mineral density \| 1 HP:0002019 \| Dyschezia \| 1 HP:0002133 \| Status epilepticus \| 1 HP:0005523 \| Lymphoproliferative disorder \| 1 HP:0003095 \| Septic arthritis \| 1 HP:0100758 \| Gangrene \| 1 HP:0005224 \| Rectal abscess \| 1 HP:0002593 \| Intestinal lymphangiectasia \| 1 HP:0000498 \| Inflammation of eyelids \| 1 HP:0100796 \| Orchitis \| 1 HP:0001009 \| Telangiectases \| 1 HP:0000979 \| Purpura \| 1 HP:0004387 \| Enterocolitis \| 1 HP:0002860 \| Squamous cell carcinoma \| 1 HP:0002749 \| Osteomalacia \| 1 HP:0003613 \| Antiphospholipid antibodies \| 1 HP:0003418 \| Back pain \| 1 HP:0001878 \| Haemolytic anaemia \| 1 HP:0001820 \| Leukonychia \| 1 HP:0100532 \| Scleritis \| 1 HP:0004322 \| Stature below 3rd percentile \| 1 HP:0012034 \| Liposarcoma \| 1 HP:0000488 \| Noninflammatory retina disease \| 1 HP:0002863 \| Myelodysplastic syndrome \| 1 HP:0010628 \| Facial palsy, unilateral or bilateral \| 1 HP:0002895 \| Papillary thyroid carcinoma \| 1 HP:0200039 \| Pustules \| 1 HP:0002578 \| Gastroparesis \| 1 HP:0005521 \| Disseminated intravascular coagulation \| 1 HP:0003712 \| Hypertrophic muscles \| 1 HP:0002028 \| Chronic diarrhea \| 1 HP:0100819 \| Intestinal fistula \| 1 HP:0007606 \| Multiple cutaneous malignancies \| 1 HP:0005305 \| Cerebral vein thrombosis \| 1 HP:0002204 \| Pulmonary embolism \| 1 HP:0001289 \| Confusion \| 1

Disease ID	39
Disease	crohn disease
Manually Symptom	UMLS \| Name(Total Manually Symptoms:84) C2707258 \| infections C2697310 \| sarcoidosis C2678504 \| osteoporosis C2364133 \| infection C2318511 \| nonalcoholic steatohepatitis C2046121 \| aortic dissection C1963274 \| vasculitis C1963198 \| pancreatitis C1963184 \| nystagmus C1963091 \| diarrhea C1562901 \| peripheral ulcerative keratitis C1550639 \| fistula C1000483 \| anemia C0949690 \| spondylarthritis C0949022 \| rectal cancer C0749914 \| urethrocutaneous fistula C0748159 \| pulmonary involvement C0699791 \| gastric carcinoma C0582430 \| adenocarcinoma of the ileum C0566602 \| primary sclerosing cholangitis C0547058 \| pseudopolyposis C0409207 \| arthritis of the hip C0346627 \| intestinal cancer C0279637 \| anal carcinoma C0278803 \| small bowel adenocarcinoma C0278803 \| adenocarcinoma of the small intestine C0272404 \| hyposplenism C0267532 \| diversion colitis C0267465 \| intestinal stricture C0267373 \| intestinal bleeding C0243001 \| intra-abdominal abscesses C0243001 \| intra-abdominal abscess C0238419 \| fournier gangrene C0238196 \| carcinoma of the small intestine C0238196 \| carcinoma of the small bowel C0238051 \| cerebral vasculitis C0235950 \| zinc deficiency C0235329 \| small bowel obstruction C0221166 \| paraparesis C0175702 \| williams syndrome C0162429 \| malnutrition C0162323 \| polyarthritis C0156272 \| vesico-intestinal fistula C0156272 \| enterovesical fistula C0152026 \| retinal vasculitis C0086981 \| sicca C0085652 \| pyoderma gangrenosum C0085077 \| sweet syndrome C0040038 \| thromboembolism C0039263 \| takayasu disease C0038833 \| superior vena cava syndrome C0038450 \| stridor C0037293 \| skin tags C0037198 \| intracranial sinus thrombosis C0035067 \| renal artery stenosis C0034895 \| rectovaginal fistulas C0034212 \| pyoderma C0033860 \| psoriasis C0033845 \| pseudotumor cerebri C0032568 \| pseudopolyp C0032285 \| pneumoniae C0030246 \| palmoplantar pustulosis C0029166 \| oral manifestations C0029166 \| oral manifestation C0027720 \| nephrosis C0027033 \| intestinal myiasis C0025037 \| meckel diverticulum C0024299 \| lymphoma C0022951 \| lactose malabsorption C0022408 \| arthropathy C0022408 \| arthropathies C0021933 \| intussusception C0021833 \| intestinal fistula C0020295 \| hydronephrosis C0019080 \| hemorrhage C0017661 \| iga nephropathy C0017536 \| giardiasis C0017181 \| gastrointestinal hemorrhage C0014743 \| erythema nodosum C0009402 \| colorectal carcinomas C0007102 \| colonic cancer C0006413 \| burkitt's lymphoma C0003504 \| aortic valve insufficiency C0001339 \| acute pancreatitis
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:166) C0016169 \| fistula \| 44 C0021831 \| bowel disease \| 25 C0009319 \| colitis \| 18 C0009450 \| infection \| 15 C0009324 \| ulcerative colitis \| 12 C0000833 \| abscess \| 11 C0030524 \| paratuberculosis \| 9 C0024299 \| lymphoma \| 9 C0042384 \| vasculitis \| 8 C0009814 \| stenosis \| 7 C0278803 \| small bowel adenocarcinoma \| 7 C0002871 \| anemia \| 7 C0033860 \| psoriasis \| 6 C0042253 \| vaginal fistula \| 6 C0040053 \| thrombosis \| 6 C0566602 \| primary sclerosing cholangitis \| 6 C0008313 \| sclerosing cholangitis \| 6 C0001418 \| adenocarcinoma \| 6 C0003864 \| arthritis \| 5 C0011991 \| diarrhea \| 5 C0002726 \| amyloidosis \| 5 C0021390 \| inflammatory bowel diseases \| 5 C0521173 \| granulomatosis \| 5 C0085652 \| pyoderma gangrenosum \| 5 C0267373 \| intestinal bleeding \| 5 C0243001 \| intra-abdominal abscess \| 5 C0030193 \| pain \| 4 C0030305 \| pancreatitis \| 4 C0001339 \| acute pancreatitis \| 4 C0039263 \| takayasu's arteritis \| 4 C0009402 \| colorectal cancer \| 4 C0029443 \| osteomyelitis \| 4 C0019158 \| hepatitis \| 4 C0034895 \| rectovaginal fistula \| 4 C0007113 \| rectal cancer \| 4 C0028754 \| obesity \| 3 C0346627 \| intestinal cancer \| 3 C0018202 \| granulomatous vasculitis \| 3 C0024141 \| systemic lupus erythematosus \| 3 C0021843 \| intestinal obstruction \| 3 C0267000 \| pyostomatitis vegetans \| 3 C0029456 \| osteoporosis \| 3 C0015967 \| fever \| 3 C0409974 \| lupus erythematosus \| 3 C0032285 \| pneumonia \| 3 C0036202 \| sarcoidosis \| 3 C0267466 \| colonic stricture \| 3 C0021845 \| bowel perforation \| 3 C0399496 \| orofacial granulomatosis \| 3 C0016412 \| folate deficiency \| 3 C1609502 \| portal venous gas \| 3 C0015672 \| fatigue \| 3 C0021843 \| bowel obstruction \| 3 C0023524 \| progressive multifocal leukoencephalopathy \| 3 C0268380 \| systemic amyloidosis \| 3 C0023885 \| liver abscess \| 3 C0267358 \| duodenal fistula \| 3 C0021079 \| immunosuppression \| 2 C0042487 \| venous thrombosis \| 2 C0949691 \| spondyloarthropathy \| 2 C0025289 \| meningitis \| 2 C0021933 \| intussusception \| 2 C0019829 \| hodgkin's lymphoma \| 2 C1994997 \| intestinal symptoms \| 2 C0162429 \| malnutrition \| 2 C0030920 \| peptic ulcer \| 2 C0008350 \| gallstones \| 2 C0156156 \| gallstone ileus \| 2 C0221014 \| secondary amyloidosis \| 2 C0024523 \| malabsorption \| 2 C0451641 \| urolithiasis \| 2 C0426576 \| gastrointestinal symptoms \| 2 C0016167 \| anal fissure \| 2 C2350476 \| orbital myositis \| 2 C0027726 \| nephrotic syndrome \| 2 C0162836 \| hidradenitis suppurativa \| 2 C0018188 \| granuloma \| 2 C0007570 \| celiac disease \| 2 C0000737 \| abdominal pain \| 2 C0030312 \| pancytopenia \| 2 C0007102 \| colon cancer \| 2 C0027121 \| myositis \| 2 C1275022 \| parastomal pyoderma gangrenosum \| 2 C0023467 \| acute myeloid leukemia \| 2 C0153425 \| small bowel cancer \| 2 C0030785 \| pelvic abscess \| 2 C0243001 \| abdominal abscess \| 2 C0019204 \| hepatocellular carcinoma \| 2 C0034895 \| rectovaginal fistulas \| 2 C0037284 \| skin lesions \| 2 C0238196 \| carcinoma of the small bowel \| 2 C0346627 \| bowel cancer \| 2 C0948008 \| ischemic stroke \| 2 C0235329 \| small bowel obstruction \| 2 C0040034 \| thrombocytopenia \| 2 C0014743 \| erythema nodosum \| 2 C0017152 \| gastritis \| 2 C0267830 \| pyogenic liver abscess \| 1 C0238196 \| small bowel carcinoma \| 1 C0039263 \| takayasu disease \| 1 C0016171 \| intestinal fistula \| 1 C0349533 \| intestinal lymphoma \| 1 C0042769 \| virus infection \| 1 C0003509 \| aortitis \| 1 C0156272 \| enterovesical fistula \| 1 C0410422 \| chronic recurrent multifocal osteomyelitis \| 1 C0263210 \| pyoderma faciale \| 1 C0011570 \| depression \| 1 C0267467 \| colonic intussusception \| 1 C0037285 \| skin manifestations \| 1 C0748159 \| pulmonary involvement \| 1 C0243001 \| intra-abdominal abscesses \| 1 C1333984 \| hepatosplenic t-cell lymphoma \| 1 C0037274 \| dermatoses \| 1 C0009402 \| colorectal carcinoma \| 1 C0023895 \| liver disease \| 1 C0243001 \| abdominal abscesses \| 1 C0041331 \| splenic tuberculosis \| 1 C0024299 \| lymphomas \| 1 C0028709 \| nutritional problems \| 1 C0085584 \| encephalopathy \| 1 C0267465 \| intestinal stricture \| 1 C0017086 \| gangrene \| 1 C0025037 \| meckel's diverticulum \| 1 C0085077 \| sweet syndrome \| 1 C0235896 \| pulmonary infiltrate \| 1 C0025162 \| toxic megacolon \| 1 C0856169 \| endothelial dysfunction \| 1 C0279637 \| carcinoma of the anus \| 1 C0162316 \| iron deficiency \| 1 C0334108 \| polyposis \| 1 C0024312 \| lymphopenia \| 1 C0002880 \| autoimmune hemolytic anemia \| 1 C0012817 \| diverticulum \| 1 C0040038 \| thromboembolism \| 1 C0010823 \| cmv infection \| 1 C0278803 \| adenocarcinoma of the small bowel \| 1 C0272404 \| hyposplenism \| 1 C0600268 \| granulomatous cheilitis \| 1 C0085077 \| sweet's syndrome \| 1 C0155305 \| ischemic optic neuropathy \| 1 C0032568 \| pseudopolyposis \| 1 C0040053 \| thrombus \| 1 C0031117 \| peripheral neuropathy \| 1 C0005944 \| metabolic bone disease \| 1 C0333039 \| phytobezoar \| 1 C0042870 \| vitamin d deficiency \| 1 C0014118 \| endocarditis \| 1 C0004030 \| aspergillosis \| 1 C0003123 \| anorexia \| 1 C0001418 \| adenocarcinomas \| 1 C0392525 \| nephrolithiasis \| 1 C0267760 \| mesenteric abscess \| 1 C0029134 \| optic neuritis \| 1 C0267465 \| intestinal stenosis \| 1 C0025309 \| meningoencephalitis \| 1 C0014356 \| enterocolitis \| 1 C0008312 \| primary biliary cirrhosis \| 1 C0043092 \| wegener's granulomatosis \| 1 C0005940 \| bone disease \| 1 C0010823 \| cytomegalovirus infection \| 1 C1332257 \| anal adenocarcinoma \| 1 C0598608 \| hyperhomocysteinemia \| 1 C0003874 \| septic arthritis \| 1 C1562901 \| peripheral ulcerative keratitis \| 1 C0002878 \| hemolytic anemia \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:836)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs10045431	24522266	55054	ATG16L1	umls:C0010346	BeFree	Detection of Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease is unrelated to the presence of single nucleotide polymorphisms rs2241880 (ATG16L1) and rs10045431 (IL12B).	0.367863153	2014	NA	5	159387525	A	C
rs10045431	18587394	3593	IL12B	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.144832032	2008	NA	5	159387525	A	C
rs10045431	20570966	3593	IL12B	umls:C0010346	GAD	[Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.]	0.144832032	2010	NA	5	159387525	A	C
rs10045431	24522266	3593	IL12B	umls:C0010346	BeFree	Detection of Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease is unrelated to the presence of single nucleotide polymorphisms rs2241880 (ATG16L1) and rs10045431 (IL12B).	0.144832032	2014	NA	5	159387525	A	C
rs1004819	17786191	149233	IL23R	umls:C0010346	BeFree	rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.	0.370597435	2007	IL23R	1	67204530	G	A
rs1004819	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67204530	G	A
rs1004819	20066736	55054	ATG16L1	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.367863153	2010	IL23R	1	67204530	G	A
rs1004819	20066736	149233	IL23R	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.370597435	2010	IL23R	1	67204530	G	A
rs1004819	20066736	64127	NOD2	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.56	2010	IL23R	1	67204530	G	A
rs1004819	20066736	50941	IBD5	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.049616576	2010	IL23R	1	67204530	G	A
rs10063949	24284447	27034	ACAD8	umls:C0010346	BeFree	A genetic variant (rs10063949-G) in the SLC23A1 ascorbate transporter locus was identified and is associated with an increased risk of CD in a white Canadian IBD cohort.	0.012757768	2014	SLC23A1	5	139383837	T	C
rs10065172	24247223	55054	ATG16L1	umls:C0010346	BeFree	We found a genetic interaction between reference SNP (rs)2241880 (ATG16L1) and rs10065172 (IRGM) in CD.	0.367863153	2014	IRGM	5	150848436	C	T
rs10065637	23128233	79722	ANKRD55	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12	2012	ANKRD55	5	56143024	C	T
rs10181042	21102463	150962	PUS10	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.127372538	2010	PUS10	2	60997124	C	T
rs10181042	21102463	150962	PUS10	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.127372538	2010	PUS10	2	60997124	C	T
rs10210302	17554300	55054	ATG16L1	umls:C0010346	GWASCAT	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	0.367863153	2007	ATG16L1	2	233250193	C	T
rs102275	21102463	746	TMEM258	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.122367032	2010	TMEM258	11	61790331	T	C
rs102275	21102463	746	TMEM258	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.122367032	2010	TMEM258	11	61790331	T	C
rs1045642	17260353	5243	ABCB1	umls:C0010346	BeFree	A total of 211 patients with Crohn's disease (CD), 97 patients with ulcerative colitis (UC), and 212 control subjects were investigated for the presence of MDR1 G2677T/A and C3435T polymorphisms.	0.026003676	2007	ABCB1	7	87509329	A	T,G
rs1045642	16633048	5243	ABCB1	umls:C0010346	BeFree	The present study examined the association of ABCB1 C3435T and G2677T/A in a large British case-control cohort of 828 Crohn's disease, 580 ulcerative colitis (UC) cases, and 285 healthy controls.	0.026003676	2006	ABCB1	7	87509329	A	T,G
rs1045642	15685540	5243	ABCB1	umls:C0010346	BeFree	This was a case-control analysis of MDR1 C3435T and G2677T SNPs in a large well-characterized Scottish white cohort (335 with ulcerative colitis [UC], 268 with Crohn's disease [CD], and 370 healthy controls).	0.026003676	2005	ABCB1	7	87509329	A	T,G
rs10486483	23128233	8935	SKAP2	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12	2012	SKAP2;LOC105375204	7	26852821	G	A
rs10495903	21102463	63892	THADA	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.122367032	2010	THADA	2	43579779	C	T
rs10495903	21102463	63892	THADA	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.122367032	2010	THADA	2	43579779	C	T
rs1049793	19670078	1610	DAO	umls:C0010346	GAD	[To analyse the possible influence of a non-synonymous single nucleotide polymorphism (SNP) of the histamine-degrading enzyme diamine oxidase (DAO) on genetic susceptibility to Crohn's disease (CD).]	0.002367032	2009	AOC1;LOC105375567	7	150860577	C	G
rs10499563	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	NA	7	22720869	T	C
rs10499563	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	NA	7	22720869	T	C
rs10499563	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	NA	7	22720869	T	C
rs10499563	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	NA	7	22720869	T	C
rs10499563	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	NA	7	22720869	T	C
rs10499563	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	NA	7	22720869	T	C
rs10499563	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	NA	7	22720869	T	C
rs10499563	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	NA	7	22720869	T	C
rs10499563	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	NA	7	22720869	T	C
rs10499563	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	NA	7	22720869	T	C
rs10499563	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	NA	7	22720869	T	C
rs10499563	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	NA	7	22720869	T	C
rs1050152	19660151	6583	SLC22A4	umls:C0010346	BeFree	Carrying a functional single nucleotide polymorphism (L503F, c. 1672 C>T) in the gene for the Na-dependent organic cation transporter (OCTN1), increases the risk of Crohn's disease (CD) in some, but not all, populations.	0.079659542	2009	SLC22A4;LOC553103	5	132340627	C	T
rs1050152	22206629	6583	SLC22A4	umls:C0010346	BeFree	The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease.	0.079659542	2012	SLC22A4;LOC553103	5	132340627	C	T
rs10734105	22412388	256536	TCERG1L	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.002367032	2012	NA	10	131373856	G	A
rs10758669	22065112	3717	JAK2	umls:C0010346	BeFree	The JAK2 variant rs10758669 in Crohn's disease: altering the intestinal barrier as one mechanism of action.	0.014006695	2012	NA	9	4981602	C	A
rs10758669	18587394	3717	JAK2	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.014006695	2008	NA	9	4981602	C	A
rs10758669	24385239	3717	JAK2	umls:C0010346	BeFree	JAK2 rs10758669 polymorphisms and susceptibility to ulcerative colitis and Crohn's disease: a meta-analysis.	0.014006695	2015	NA	9	4981602	C	A
rs10758669	18587394	10171	RCL1	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.002367032	2008	NA	9	4981602	C	A
rs10761659	21102463	22891	ZNF365	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.137383549	2010	NA	10	62685804	A	G
rs10761659	17554300	22891	ZNF365	umls:C0010346	GAD	[Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.]	0.137383549	2007	NA	10	62685804	A	G
rs10801047	17554261	339479	BRINP3	umls:C0010346	GAD	[Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.]	0.002367032	2007	NA	1	191590226	A	T
rs10883365	21514341	159296	NKX2-3	umls:C0010346	BeFree	A total of 344 patients with Crohn's disease (CD), 253 patients with ulcerative colitis (UC), and 243 healthy controls (HCs) were genotyped for 3 tag-single nucleotide polymorphisms (SNPs; rs10883365, rs888208, and rs11596008) around NKX2.3.	0.274386036	2011	LINC01475	10	99528007	G	A
rs10883365	17554261	2805	GOT1	umls:C0010346	GAD	[Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.]	0.007372538	2007	LINC01475	10	99528007	G	A
rs10883365	17554300	2805	GOT1	umls:C0010346	GAD	[Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.]	0.007372538	2007	LINC01475	10	99528007	G	A
rs10883365	17554261	101927324	LINC01475	umls:C0010346	GWASCAT	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	0.12	2007	LINC01475	10	99528007	G	A
rs10883365	17554300	101927324	LINC01475	umls:C0010346	GWASCAT	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	0.12	2007	LINC01475	10	99528007	G	A
rs10889676	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67256884	C	A
rs10889677	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67259437	C	A
rs10947261	23850713	101929163	LOC101929163	umls:C0010346	GWASCAT	Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.	0.12	2014	BTNL2;LOC101929163	6	32405455	G	T
rs10947261	23850713	56244	BTNL2	umls:C0010346	GWASCAT	Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.	0.125362824	2014	BTNL2;LOC101929163	6	32405455	G	T
rs10975003	21831733	3717	JAK2	umls:C0010346	BeFree	Except rs10975003 from the JAK2 locus, none showed positive association with Crohn's disease.	0.014006695	2011	NA	9	5213687	T	C
rs10995271	18587394	22891	ZNF365	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.137383549	2008	NA	10	62678726	G	C
rs11175593	18587394	120892	LRRK2	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.006362715	2008	LOC105369735	12	40208138	C	T
rs11175593	18587394	283463	MUC19	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.125005506	2008	LOC105369735	12	40208138	C	T
rs11190140	18587394	101927324	LINC01475	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.12	2008	NKX2-3;LINC01475	10	99531836	T	C
rs11190140	18587394	159296	NKX2-3	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.274386036	2008	NKX2-3;LINC01475	10	99531836	T	C
rs11190141	22412388	159296	NKX2-3	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.274386036	2012	NKX2-3;LINC01475	10	99532633	C	T
rs11190141	22412388	101927324	LINC01475	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.12	2012	NKX2-3;LINC01475	10	99532633	C	T
rs11190141	22412388	159296	NKX2-3	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.274386036	2012	NKX2-3;LINC01475	10	99532633	C	T
rs11209002	17804789	400757	C1orf141	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.12	2007	C1orf141	1	67124778	T	C
rs11209003	17804789	400757	C1orf141	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.12	2007	C1orf141	1	67135449	G	T
rs11209026	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	IL23R	1	67240275	G	A
rs11209026	20082483	64127	NOD2	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.56	2010	IL23R	1	67240275	G	A
rs11209026	25259511	64127	NOD2	umls:C0010346	BeFree	We observed the association between Crohn's disease and NOD2 (rs17313265, 0.28 in CD, 0.19 in controls, OR 1.5, p = 9×10-6) and IL23R (rs11209026, 0.026 in CD, 0.0.071 in controls, OR 0.4, p = 3.8×10-4).	0.56	2014	IL23R	1	67240275	G	A
rs11209026	20192940	149233	IL23R	umls:C0010346	GAD	[Association of the interleukin-23 receptor gene variant rs11209026 with Crohn's disease in German children.]	0.370597435	2010	IL23R	1	67240275	G	A
rs11209026	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	IL23R	1	67240275	G	A
rs11209026	25259511	149233	IL23R	umls:C0010346	BeFree	We observed the association between Crohn's disease and NOD2 (rs17313265, 0.28 in CD, 0.19 in controls, OR 1.5, p = 9×10-6) and IL23R (rs11209026, 0.026 in CD, 0.0.071 in controls, OR 0.4, p = 3.8×10-4).	0.370597435	2014	IL23R	1	67240275	G	A
rs11209026	17894849	149233	IL23R	umls:C0010346	BeFree	IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease.	0.370597435	2007	IL23R	1	67240275	G	A
rs11209026	20082483	55054	ATG16L1	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.367863153	2010	IL23R	1	67240275	G	A
rs11209026	22293688	149233	IL23R	umls:C0010346	GAD	[One is SNP rs11209026 in exon 9 of IL23R for association with Crohn's disease, which is predicted to be probably damaging by PolyPhen2.]	0.370597435	2012	IL23R	1	67240275	G	A
rs11209026	17447842	149233	IL23R	umls:C0010346	GWASCAT	Two of these (IL23R on Chromosome 1 and CARD15 on Chromosome 16) correspond to genes previously reported to be associated with CD.	0.370597435	2007	IL23R	1	67240275	G	A
rs11209026	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	IL23R	1	67240275	G	A
rs11209026	17877509	149233	IL23R	umls:C0010346	BeFree	Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis.	0.370597435	2007	IL23R	1	67240275	G	A
rs11209026	22293688	149233	IL23R	umls:C0010346	GWASCAT	One is SNP rs11209026 in exon 9 of IL23R for association with Crohn's disease, which is predicted to be probably damaging by PolyPhen2.	0.370597435	2012	IL23R	1	67240275	G	A
rs11209026	17894849	55054	ATG16L1	umls:C0010346	BeFree	IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease.	0.367863153	2007	IL23R	1	67240275	G	A
rs11209026	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67240275	G	A
rs11209026	24971461	26191	PTPN22	umls:C0010346	BeFree	After Bonferroni correction for multiple testing, both the homozygous and the heterozygous variant genotypes of IL23R G>A(rs11209026) (OR(CD,adj): 0.38, 95% CI: 0.21-0.67, p = 0.03; OR(IBD,adj) 0.43, 95% CI: 0.28-0.67, p = 0.007) and PTPN22 1858 G>A(rs2476601) (OR(CD,unadj) 0.54, 95% CI: 0.41-0.72, p = 7*10-4; OR(IBD,unadj): 0.61, 95% CI: 0.48-0.77, p = 0.001) were associated with reduced risk of CD.	0.153757276	2014	IL23R	1	67240275	G	A
rs11209026	24971461	149233	IL23R	umls:C0010346	BeFree	After Bonferroni correction for multiple testing, both the homozygous and the heterozygous variant genotypes of IL23R G>A(rs11209026) (OR(CD,adj): 0.38, 95% CI: 0.21-0.67, p = 0.03; OR(IBD,adj) 0.43, 95% CI: 0.28-0.67, p = 0.007) and PTPN22 1858 G>A(rs2476601) (OR(CD,unadj) 0.54, 95% CI: 0.41-0.72, p = 7*10-4; OR(IBD,unadj): 0.61, 95% CI: 0.48-0.77, p = 0.001) were associated with reduced risk of CD.	0.370597435	2014	IL23R	1	67240275	G	A
rs11209026	21102463	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.370597435	2010	IL23R	1	67240275	G	A
rs11209026	18030204	149233	IL23R	umls:C0010346	BeFree	Evaluation of the interleukin-23 receptor gene coding variant R381Q in pediatric and adult Crohn disease.	0.370597435	2007	IL23R	1	67240275	G	A
rs11209026	20192940	149233	IL23R	umls:C0010346	BeFree	Association of the interleukin-23 receptor gene variant rs11209026 with Crohn's disease in German children.	0.370597435	2010	IL23R	1	67240275	G	A
rs11209026	20082483	149233	IL23R	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.370597435	2010	IL23R	1	67240275	G	A
rs11209026	22936669	149233	IL23R	umls:C0010346	GWASCAT	A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.	0.370597435	2013	IL23R	1	67240275	G	A
rs11209026	22412388	149233	IL23R	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.370597435	2012	IL23R	1	67240275	G	A
rs11209026	18383363	149233	IL23R	umls:C0010346	BeFree	Recent studies have shown that a nonsynonymous single-nucleotide polymorphism (SNP) (Arg381Gln; rs11209026) in the interleukin-23 receptor (IL-23R) gene on chromosome 1p31 is associated with Crohn's disease and psoriasis.	0.370597435	2008	IL23R	1	67240275	G	A
rs11209026	22293688	149233	IL23R	umls:C0010346	BeFree	One is SNP rs11209026 in exon 9 of IL23R for association with Crohn's disease, which is predicted to be probably damaging by PolyPhen2.	0.370597435	2012	IL23R	1	67240275	G	A
rs11229030	22412388	29015	SLC43A3	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.002367032	2012	NA	11	57435536	C	T
rs1142287	21102463	10067	SCAMP3	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.122367032	2010	SCAMP3	1	155260340	C	T
rs11465788	19700857	149233	IL23R	umls:C0010346	BeFree	Contribution of rs11465788 in IL23R gene to Crohn's disease susceptibility and phenotype in Chinese population.	0.370597435	2009	IL23R	1	67182611	C	T
rs11465802	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67219915	A	C,T
rs11465804	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67236843	T	G
rs11465804	18587394	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.370597435	2008	IL23R	1	67236843	T	G
rs11465804	20570966	149233	IL23R	umls:C0010346	GWASCAT	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	0.370597435	2010	IL23R	1	67236843	T	G
rs11465996	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	LY96	8	73989727	C	G
rs11465996	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	LY96	8	73989727	C	G
rs11465996	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	LY96	8	73989727	C	G
rs11465996	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	LY96	8	73989727	C	G
rs11465996	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	LY96	8	73989727	C	G
rs11465996	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	LY96	8	73989727	C	G
rs11465996	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	LY96	8	73989727	C	G
rs11465996	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	LY96	8	73989727	C	G
rs11465996	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	LY96	8	73989727	C	G
rs11465996	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	LY96	8	73989727	C	G
rs11465996	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	LY96	8	73989727	C	G
rs11465996	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	LY96	8	73989727	C	G
rs11465996	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	LY96	8	73989727	C	G
rs11465996	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	LY96	8	73989727	C	G
rs11465996	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	LY96	8	73989727	C	G
rs11564258	21102463	283463	MUC19	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.125005506	2010	MUC19;LOC105369736	12	40398498	G	A
rs11574514	22412388	5699	PSMB10	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.122638474	2012	PSMB10	16	67937477	C	T
rs11574514	22412388	5699	PSMB10	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.122638474	2012	PSMB10	16	67937477	C	T
rs11584383	18587394	647215	MROH3P	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.122367032	2008	MROH3P	1	200966738	T	C
rs11584383	18587394	647215	MROH3P	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.122367032	2008	MROH3P	1	200966738	T	C
rs11596008	21514341	159296	NKX2-3	umls:C0010346	BeFree	A total of 344 patients with Crohn's disease (CD), 253 patients with ulcerative colitis (UC), and 243 healthy controls (HCs) were genotyped for 3 tag-single nucleotide polymorphisms (SNPs; rs10883365, rs888208, and rs11596008) around NKX2.3.	0.274386036	2011	LINC01475	10	99527557	C	T
rs11676348	26071399	3579	CXCR2	umls:C0010346	BeFree	The minor allele (T) in SNP rs11676348, located downstream from CXCR2 that has been implicated in CRC progression, is associated with a lower risk of CRC, particularly tumors with a mucinous component, Crohn's-like reaction and MSI-high.	0.000271442	2015	NA	2	218145423	C	T
rs11742570	21102463	1601	DAB2	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.016569224	2010	NA	5	40410482	T	C
rs11805303	17554300	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	0.370597435	2007	IL23R	1	67209833	C	T
rs11871801	21102463	284119	PTRF	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.122367032	2010	PTRF	17	42418754	A	C
rs11924265	25557950	9223	MAGI1	umls:C0010346	GWASCAT	Identification of risk loci for Crohn's disease phenotypes using a genome-wide association study.	0.12	2014	MAGI1	3	65774667	T	C
rs11938228	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	TLR2	4	153700794	C	A
rs11938228	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	TLR2	4	153700794	C	A
rs11938228	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR2	4	153700794	C	A
rs11938228	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	TLR2	4	153700794	C	A
rs11938228	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	TLR2	4	153700794	C	A
rs11938228	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	TLR2	4	153700794	C	A
rs11938228	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	TLR2	4	153700794	C	A
rs11938228	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR2	4	153700794	C	A
rs11938228	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	TLR2	4	153700794	C	A
rs11938228	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	TLR2	4	153700794	C	A
rs11938228	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	TLR2	4	153700794	C	A
rs11938228	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	TLR2	4	153700794	C	A
rs1200332	25259511	11177	BAZ1A	umls:C0010346	BeFree	We also observed suggestive evidence for the association of the BAZ1A promoter SNP with CD (rs1200332, 0.45 in CD, 0.35 in controls, OR 1.5, p = 2×10-6).	0.000271442	2014	NA	14	34897929	T	C
rs12035082	17554261	356	FASLG	umls:C0010346	GAD	[Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.]	0.012378044	2007	NA	1	172929237	T	C
rs12212067	24035192	2309	FOXO3	umls:C0010346	BeFree	We identify a noncoding polymorphism in FOXO3A (rs12212067: T > G) at which the minor (G) allele, despite not being associated with disease susceptibility, is associated with a milder course of Crohn's disease and rheumatoid arthritis and with increased risk of severe malaria.	0.000814326	2013	FOXO3	6	108659993	T	G
rs12212067	25365249	64127	NOD2	umls:C0010346	BeFree	The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067.	0.56	2014	FOXO3	6	108659993	T	G
rs12212067	25365249	2309	FOXO3	umls:C0010346	BeFree	The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067.	0.000814326	2014	FOXO3	6	108659993	T	G
rs12242110	21102463	219771	CCNY	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.256926542	2010	CCNY	10	35246767	A	G
rs12377632	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	TLR4	9	117710452	T	C
rs12377632	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	TLR4	9	117710452	T	C
rs12377632	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	TLR4	9	117710452	T	C
rs1250544	22482804	57178	ZMIZ1	umls:C0010346	GWASCAT	We identified seven susceptibility loci outside the human leukocyte antigen region (9p24 near JAK2, 10q22 at ZMIZ1, 11q13 near PRDX5, 16p13 near SOCS1, 17q21 at STAT3, 19p13 near FUT2, and 22q11 at YDJC) shared between PS and CD with genome-wide significance (p < 5 × 10(-8)) and confirmed four already established PS and CD risk loci (IL23R, IL12B, REL, and TYK2).	0.125005506	2012	ZMIZ1	10	79273128	G	A
rs1250550	21102463	57178	ZMIZ1	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.125005506	2010	ZMIZ1	10	79300560	C	A
rs1250550	21102463	57178	ZMIZ1	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.125005506	2010	ZMIZ1	10	79300560	C	A
rs1250569	25489960	57178	ZMIZ1	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.125005506	2015	ZMIZ1	10	79285450	T	C
rs1250569	25489960	2859	GPR35	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.000271442	2015	ZMIZ1	10	79285450	T	C
rs1250569	25489960	29761	USP25	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.002638474	2015	ZMIZ1	10	79285450	T	C
rs1250569	25489960	159296	NKX2-3	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.274386036	2015	ZMIZ1	10	79285450	T	C
rs1250569	25489960	22891	ZNF365	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.137383549	2015	ZMIZ1	10	79285450	T	C
rs1250569	25489960	5771	PTPN2	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.269023212	2015	ZMIZ1	10	79285450	T	C
rs12521868	21102463	441108	C5orf56	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.127101096	2010	C5orf56	5	132448701	G	T
rs12521868	21102463	441108	C5orf56	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.127101096	2010	C5orf56	5	132448701	G	T
rs12677663	22412388	157869	SBSPON	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.122367032	2012	SBSPON	8	73095112	G	T
rs12677663	22412388	157869	SBSPON	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.122367032	2012	SBSPON	8	73095112	G	T
rs12720356	21102463	7297	TYK2	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.245005506	2010	TYK2	19	10359299	A	C
rs12720356	21102463	7297	TYK2	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.245005506	2010	TYK2	19	10359299	A	C
rs12721602	21830270	8856	NR1I2	umls:C0010346	BeFree	Genomic DNA from 2823 individuals of Caucasian origin including 859 patients with Crohn's disease (CD), 464 patients with ulcerative colitis (UC), and 1500 healthy, unrelated controls was analyzed for eight PXR/NR1I2 single nucleotide polymorphisms (SNPs) (rs12721602 (-25564), rs3814055 (-25385), rs1523128 (-24756), rs1523127 (-24381), rs45610735 = p.Gly36Arg (+106), rs6785049 (+7635), rs2276707 (+8055), and rs3814057 (+11156)).	0.006991475	2011	NR1I2	3	119781009	G	A
rs12721607	21830270	8856	NR1I2	umls:C0010346	BeFree	Genomic DNA from 2823 individuals of Caucasian origin including 859 patients with Crohn's disease (CD), 464 patients with ulcerative colitis (UC), and 1500 healthy, unrelated controls was analyzed for eight PXR/NR1I2 single nucleotide polymorphisms (SNPs) (rs12721602 (-25564), rs3814055 (-25385), rs1523128 (-24756), rs1523127 (-24381), rs45610735 = p.Gly36Arg (+106), rs6785049 (+7635), rs2276707 (+8055), and rs3814057 (+11156)).	0.006991475	2011	NR1I2	3	119807356	G	A
rs12722489	21102463	3559	IL2RA	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.24554839	2010	IL2RA	10	6060049	C	T
rs12722489	21102463	3559	IL2RA	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.24554839	2010	IL2RA	10	6060049	C	T
rs1297265	23511034	3717	JAK2	umls:C0010346	BeFree	FOS, UBE2L3, the JAK2 gene region, and rs1297265 at chromosome arm 21q21.1 likely play a role in both Crohn's disease and UC.	0.014006695	2013	LOC101927745	21	15444732	A	G
rs12994997	23128233	55054	ATG16L1	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.367863153	2012	ATG16L1	2	233264857	G	A
rs13003464	22412388	150962	PUS10	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.127372538	2012	PUS10	2	60959694	A	G
rs13003464	22412388	150962	PUS10	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.127372538	2012	PUS10	2	60959694	A	G
rs13073817	21102463	6304	SATB1	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.002367032	2010	NA	3	18665366	G	A
rs13126505	23128233	55024	BANK1	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12	2012	BANK1	4	101944147	G	A
rs13361189	19491842	345611	IRGM	umls:C0010346	BeFree	The aim of this study was to determine the role of the ATG16L1 (rs2241880) and IRGM (rs13361189 and rs4958847) genes polymorphism in Crohn's disease (CD) and ulcerative colitis (UC).	0.17026908	2009	NA	5	150843825	T	C
rs13361189	19491842	55054	ATG16L1	umls:C0010346	BeFree	The aim of this study was to determine the role of the ATG16L1 (rs2241880) and IRGM (rs13361189 and rs4958847) genes polymorphism in Crohn's disease (CD) and ulcerative colitis (UC).	0.367863153	2009	NA	5	150843825	T	C
rs13361189	17554261	85027	SMIM3	umls:C0010346	GAD	[Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.]	0.002367032	2007	NA	5	150843825	T	C
rs13428812	21102463	1788	DNMT3A	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.242367032	2010	DNMT3A	2	25269598	A	G
rs13428812	21102463	1788	DNMT3A	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.242367032	2010	DNMT3A	2	25269598	A	G
rs1343151	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67253446	G	A
rs1373692	17447842	1601	DAB2	umls:C0010346	GAD	[Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4.]	0.016569224	2007	NA	5	40431081	A	C
rs1398024	18723019	256815	C10orf67	umls:C0010346	GAD	[Our study demonstrates that the combined analysis of different, albeit clinically related, phenotypes can lead to the identification of common susceptibility loci.]	0.002367032	2008	NA	10	23376509	G	T
rs1405655	21245992	4790	NFKB1	umls:C0010346	BeFree	Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.	0.008262808	2011	NR1H2	19	50379362	T	C
rs1405655	21245992	8856	NR1I2	umls:C0010346	BeFree	Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.	0.006991475	2011	NR1H2	19	50379362	T	C
rs1456893	18587394	100130988	C7orf72	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.002367032	2008	NA	7	50230076	G	A
rs145922845	12825869	3586	IL10	umls:C0010346	BeFree	A Gly15Arg mutation in the interleukin-10 gene reduces secretion of interleukin-10 in Crohn disease.	0.165525085	2003	IL10	1	206772393	C	T
rs151181	21102463	1201	CLN3	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.122367032	2010	CLN3;NPIPB8	16	28479196	T	C
rs151181	21102463	1201	CLN3	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.122367032	2010	CLN3;NPIPB8	16	28479196	T	C
rs1523127	21245992	4790	NFKB1	umls:C0010346	BeFree	Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.	0.008262808	2011	NR1I2	3	119782192	C	A
rs1523127	21830270	8856	NR1I2	umls:C0010346	BeFree	Genomic DNA from 2823 individuals of Caucasian origin including 859 patients with Crohn's disease (CD), 464 patients with ulcerative colitis (UC), and 1500 healthy, unrelated controls was analyzed for eight PXR/NR1I2 single nucleotide polymorphisms (SNPs) (rs12721602 (-25564), rs3814055 (-25385), rs1523128 (-24756), rs1523127 (-24381), rs45610735 = p.Gly36Arg (+106), rs6785049 (+7635), rs2276707 (+8055), and rs3814057 (+11156)).	0.006991475	2011	NR1I2	3	119782192	C	A
rs1523127	21245992	8856	NR1I2	umls:C0010346	BeFree	Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.	0.006991475	2011	NR1I2	3	119782192	C	A
rs1523128	21830270	8856	NR1I2	umls:C0010346	BeFree	Genomic DNA from 2823 individuals of Caucasian origin including 859 patients with Crohn's disease (CD), 464 patients with ulcerative colitis (UC), and 1500 healthy, unrelated controls was analyzed for eight PXR/NR1I2 single nucleotide polymorphisms (SNPs) (rs12721602 (-25564), rs3814055 (-25385), rs1523128 (-24756), rs1523127 (-24381), rs45610735 = p.Gly36Arg (+106), rs6785049 (+7635), rs2276707 (+8055), and rs3814057 (+11156)).	0.006991475	2011	NR1I2	3	119781817	A	G
rs1551398	18587394	10221	TRIB1	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.007101096	2008	LOC105375745	8	125527809	G	A
rs1554973	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	NA	9	117718534	T	C
rs1554973	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	NA	9	117718534	T	C
rs1554973	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	NA	9	117718534	T	C
rs1554973	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	NA	9	117718534	T	C
rs1554973	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	NA	9	117718534	T	C
rs1554973	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	NA	9	117718534	T	C
rs1554973	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	NA	9	117718534	T	C
rs1554973	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	NA	9	117718534	T	C
rs1554973	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	NA	9	117718534	T	C
rs1554973	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	NA	9	117718534	T	C
rs1554973	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	NA	9	117718534	T	C
rs1554973	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	NA	9	117718534	T	C
rs1554973	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	NA	9	117718534	T	C
rs1554973	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	NA	9	117718534	T	C
rs1554973	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	NA	9	117718534	T	C
rs1568885	24707144	7124	TNF	umls:C0010346	BeFree	Association of rs1568885, rs1813443 and rs4411591 polymorphisms with anti-TNF medication response in Greek patients with Crohn's disease.	0.422294957	2014	NA	7	13597906	T	A
rs17221417	17554300	64127	NOD2	umls:C0010346	GWASCAT	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	0.56	2007	NOD2	16	50705671	C	G
rs17234657	17554300	1601	DAB2	umls:C0010346	GAD	[Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.]	0.016569224	2007	NA	5	40401407	T	G
rs17293632	21102463	4088	SMAD3	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.242638474	2010	SMAD3	15	67150258	C	T
rs17293632	21102463	4088	SMAD3	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.242638474	2010	SMAD3	15	67150258	C	T
rs17309827	21102463	63027	SLC22A23	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.13183516	2010	SLC22A23	6	3433084	T	G
rs17309827	21102463	63027	SLC22A23	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.13183516	2010	SLC22A23	6	3433084	T	G
rs17313265	25259511	149233	IL23R	umls:C0010346	BeFree	We observed the association between Crohn's disease and NOD2 (rs17313265, 0.28 in CD, 0.19 in controls, OR 1.5, p = 9×10-6) and IL23R (rs11209026, 0.026 in CD, 0.0.071 in controls, OR 0.4, p = 3.8×10-4).	0.370597435	2014	NOD2	16	50713793	C	T
rs17313265	25259511	64127	NOD2	umls:C0010346	BeFree	We observed the association between Crohn's disease and NOD2 (rs17313265, 0.28 in CD, 0.19 in controls, OR 1.5, p = 9×10-6) and IL23R (rs11209026, 0.026 in CD, 0.0.071 in controls, OR 0.4, p = 3.8×10-4).	0.56	2014	NOD2	16	50713793	C	T
rs1736135	18587394	8204	NRIP1	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.002367032	2008	LOC101927745	21	15432901	T	C
rs17695092	23128233	80315	CPEB4	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.122367032	2012	CPEB4	5	173910850	T	G
rs1793004	17684544	4745	NELL1	umls:C0010346	GAD	[Subsequent fine mapping and replication in an independent sample of 454 French/Canadian CD trios supported the authenticity of the NELL1 association.]	0.005005506	2007	NELL1	11	20677383	C	G
rs1799964	21102463	7124	TNF	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.422294957	2010	LTA;TNF;LOC100287329	6	31574531	T	C
rs1799964	21102463	4049	LTA	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.130911214	2010	LTA;TNF;LOC100287329	6	31574531	T	C
rs1800629	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	TNF	6	31575254	G	A
rs1800629	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	TNF	6	31575254	G	A
rs1800629	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	TNF	6	31575254	G	A
rs1801282	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	PPARG	3	12351626	C	G
rs1801282	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	PPARG	3	12351626	C	G
rs1801282	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	PPARG	3	12351626	C	G
rs1813443	24707144	7124	TNF	umls:C0010346	BeFree	Association of rs1568885, rs1813443 and rs4411591 polymorphisms with anti-TNF medication response in Greek patients with Crohn's disease.	0.422294957	2014	CNTN5	11	100140279	G	C
rs181359	21102463	7332	UBE2L3	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.125005506	2010	UBE2L3	22	21574352	G	A
rs181359	21102463	7332	UBE2L3	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.125005506	2010	UBE2L3	22	21574352	G	A
rs1816702	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	TLR2	4	153688371	T	C
rs1816702	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR2	4	153688371	T	C
rs1816702	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	TLR2	4	153688371	T	C
rs1816702	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	TLR2	4	153688371	T	C
rs1816702	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	TLR2	4	153688371	T	C
rs1816702	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	TLR2	4	153688371	T	C
rs1816702	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	TLR2	4	153688371	T	C
rs1816702	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	TLR2	4	153688371	T	C
rs1816702	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	TLR2	4	153688371	T	C
rs1816702	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	TLR2	4	153688371	T	C
rs1816702	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	TLR2	4	153688371	T	C
rs1816702	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	TLR2	4	153688371	T	C
rs1816702	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	TLR2	4	153688371	T	C
rs1816702	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	TLR2	4	153688371	T	C
rs1816702	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR2	4	153688371	T	C
rs181856615	20195480	56144	PCDHA4	umls:C0010346	BeFree	The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.	0.000271442	2010	PCDHA9;PCDHA11;PCDHA10;PCDHA8;PCDHA7;PCDHA6;PCDHA5;PCDHA4;PCDHA3;PCDHA2;PCDHA1	5	140870462	G	A
rs1847472	21102463	60468	BACH2	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.242909916	2010	BACH2	6	90263440	C	A
rs1847472	21102463	60468	BACH2	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.242909916	2010	BACH2	6	90263440	C	A
rs1861494	25171510	3458	IFNG	umls:C0010346	BeFree	Peripheral T cells of UC and Crohn's disease (CD) patients were genotyped for rs1861494 and analyzed for allele-specific and IFNG promoter methylation.	0.130334654	2015	IFNG	12	68157629	C	T
rs187084	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	TLR9	3	52227015	A	G
rs187084	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	TLR9	3	52227015	A	G
rs187084	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	TLR9	3	52227015	A	G
rs187084	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	TLR9	3	52227015	A	G
rs187084	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	TLR9	3	52227015	A	G
rs187084	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	TLR9	3	52227015	A	G
rs187084	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR9	3	52227015	A	G
rs187084	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	TLR9	3	52227015	A	G
rs187084	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	TLR9	3	52227015	A	G
rs187084	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	TLR9	3	52227015	A	G
rs187084	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR9	3	52227015	A	G
rs187084	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	TLR9	3	52227015	A	G
rs1893217	21102463	5771	PTPN2	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.269023212	2010	PTPN2	18	12809341	A	G
rs1906493	22412388	10221	TRIB1	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.007101096	2012	NA	8	126080638	G	T
rs191901394	18617779	64127	NOD2	umls:C0010346	BeFree	Our aim was to evaluate the frequency of CX3CR1 V249I and T280M polymorphisms and NOD2/CARD15 mutations in Crohn's disease patients and to search for a relationship with phenotype.	0.56	2008	NOD2	16	50710831	C	T
rs1992660	17684544	1601	DAB2	umls:C0010346	GAD	[Systematic association mapping identifies NELL1 as a novel IBD disease gene.]	0.016569224	2007	NA	5	40414965	C	T
rs1992660	17684544	5734	PTGER4	umls:C0010346	GAD	[Systematic association mapping identifies NELL1 as a novel IBD disease gene.]	0.018555193	2007	NA	5	40414965	C	T
rs1998598	21102463	163486	DENND1B	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.242367032	2010	DENND1B	1	197758512	A	G
rs1998598	21102463	163486	DENND1B	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.242367032	2010	DENND1B	1	197758512	A	G
rs2024092	23128233	22904	SBNO2	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.124734064	2012	SBNO2	19	1124032	G	A
rs2032582	15685540	5243	ABCB1	umls:C0010346	BeFree	This was a case-control analysis of MDR1 C3435T and G2677T SNPs in a large well-characterized Scottish white cohort (335 with ulcerative colitis [UC], 268 with Crohn's disease [CD], and 370 healthy controls).	0.026003676	2005	ABCB1	7	87531302	A	T,C
rs2032582	17260353	5243	ABCB1	umls:C0010346	BeFree	A total of 211 patients with Crohn's disease (CD), 97 patients with ulcerative colitis (UC), and 212 control subjects were investigated for the presence of MDR1 G2677T/A and C3435T polymorphisms.	0.026003676	2007	ABCB1	7	87531302	A	T,C
rs2032582	16633048	5243	ABCB1	umls:C0010346	BeFree	The present study examined the association of ABCB1 C3435T and G2677T/A in a large British case-control cohort of 828 Crohn's disease, 580 ulcerative colitis (UC) cases, and 285 healthy controls.	0.026003676	2006	ABCB1	7	87531302	A	T,C
rs2032582	19115152	5243	ABCB1	umls:C0010346	BeFree	In this study, the G2677T/A polymorphism observed in the MDR1 gene was not found to be a risk factor for Crohn's disease or ulcerative colitis.	0.026003676	2008	ABCB1	7	87531302	A	T,C
rs2043211	20182451	114548	NLRP3	umls:C0010346	BeFree	Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease.	0.140812605	2010	CARD8	19	48234449	A	T
rs2043211	18092344	22900	CARD8	umls:C0010346	BeFree	No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts.	0.008544182	2008	CARD8	19	48234449	A	T
rs2043211	20182451	64127	NOD2	umls:C0010346	BeFree	We found that the presence of the minor allele of rs2043211 with the major allele of rs35829419 conferred a protective effect against Crohn's disease (and vice versa), which intensified in the absence of NOD2 mutations (P(1,2/1,1)=0.009, odds ratio (OR)=0.66, 95% confidence interval (CI) (0.48-0.90); P(1,1/1,2)=0.015, OR=0.35, 95% CI (0.15-0.82)).	0.56	2010	CARD8	19	48234449	A	T
rs2043211	20182451	22900	CARD8	umls:C0010346	BeFree	Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease.	0.008544182	2010	CARD8	19	48234449	A	T
rs2043211	20182451	22900	CARD8	umls:C0010346	GAD	[Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease.]	0.008544182	2010	CARD8	19	48234449	A	T
rs2043211	23506543	22900	CARD8	umls:C0010346	BeFree	The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn's disease.	0.008544182	2013	CARD8	19	48234449	A	T
rs2058660	21102463	8807	IL18RAP	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.12973957	2010	IL18RAP	2	102437989	G	A
rs2058660	21102463	8807	IL18RAP	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.12973957	2010	IL18RAP	2	102437989	G	A
rs2064689	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67187327	G	A
rs2066842	18715515	6583	SLC22A4	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.079659542	2008	NOD2	16	50710713	C	A,T
rs2066842	18715515	64127	NOD2	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.56	2008	NOD2	16	50710713	C	A,T
rs2066842	18715515	6584	SLC22A5	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.079669474	2008	NOD2	16	50710713	C	A,T
rs2066842	18715515	55054	ATG16L1	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.367863153	2008	NOD2	16	50710713	C	A,T
rs2066842	12115195	64127	NOD2	umls:C0010346	BeFree	A case-control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro(268)Ser, Arg(702)Trp, Gly(908)Arg, and Leu(1007)fsinsC) was performed in 229 cases of primary AS with no diagnosed inflammatory bowel disease (IBD), 197 cases of AS associated with IBD (referred to as colitic spondylarthritis; comprising 78 with CD and 119 with ulcerative colitis [UC]), and 229 ethnically matched, healthy controls.	0.56	2002	NOD2	16	50710713	C	A,T
rs2066843	21209938	64127	NOD2	umls:C0010346	BeFree	The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.	0.56	2010	NOD2	16	50711288	C	A,T
rs2066844	18541930	64127	NOD2	umls:C0010346	BeFree	The R702W mutation of CARD15 gene was associated with Crohn's disease in the Iranian population.	0.56	2008	NOD2	16	50712015	C	T
rs2066844	16819970	64127	NOD2	umls:C0010346	BeFree	In cells carrying the Crohn-associated NOD2 variant R702W the NF-kappaB response was significantly diminished.	0.56	2006	NOD2	16	50712015	C	T
rs2066844	20082483	64127	NOD2	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.56	2010	NOD2	16	50712015	C	T
rs2066844	15527324	64127	NOD2	umls:C0010346	BeFree	Three mutations (R702W, G908R, and 1007fs) within the CARD15 gene have been identified as independent risk factors for the development of Crohn's disease (CD).	0.56	2004	NOD2	16	50712015	C	T
rs2066844	15202784	64127	NOD2	umls:C0010346	BeFree	A frameshift mutation (Leu1007fsinsC) and two missense mutations (Gly908Arg and Arg702Trp) in the NOD2/CARD15 gene are strongly associated with susceptibility to Crohn's disease.	0.56	2004	NOD2	16	50712015	C	T
rs2066844	17355968	64127	NOD2	umls:C0010346	BeFree	In this study, we demonstrate that membrane-bound versions of NOD2 and Crohn disease-associated mutants R702W and G908R are capable of responding to MDP and activating the NF-kappaB pathway from this location.	0.56	2007	NOD2	16	50712015	C	T
rs2066844	12115195	64127	NOD2	umls:C0010346	BeFree	A case-control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro(268)Ser, Arg(702)Trp, Gly(908)Arg, and Leu(1007)fsinsC) was performed in 229 cases of primary AS with no diagnosed inflammatory bowel disease (IBD), 197 cases of AS associated with IBD (referred to as colitic spondylarthritis; comprising 78 with CD and 119 with ulcerative colitis [UC]), and 229 ethnically matched, healthy controls.	0.56	2002	NOD2	16	50712015	C	T
rs2066844	21690088	64127	NOD2	umls:C0010346	BeFree	We also show that the three main Crohn disease-associated mutants of NOD2 (1007fs, R702W, G908R) form an interaction with RIG-I and negatively regulate its signaling to a greater extent than wild-type NOD2.	0.56	2011	NOD2	16	50712015	C	T
rs2066844	17355968	19	ABCA1	umls:C0010346	BeFree	In this study, we demonstrate that membrane-bound versions of NOD2 and Crohn disease-associated mutants R702W and G908R are capable of responding to MDP and activating the NF-kappaB pathway from this location.	0.000542884	2007	NOD2	16	50712015	C	T
rs2066844	19570052	64127	NOD2	umls:C0010346	BeFree	NOD2/CARD15 is involved in the innate immune response and three polymorphisms in this gene (Arg702Trp rs2066844, Gly908Arg rs2066845 and Leu1007fsinsC rs5743293) have been associated with risk of the rare Crohn's disease.	0.56	2010	NOD2	16	50712015	C	T
rs2066844	20082483	149233	IL23R	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.370597435	2010	NOD2	16	50712015	C	T
rs2066844	16133969	64127	NOD2	umls:C0010346	BeFree	Furthermore, the three main mutations of CARD15/NOD2 (R702W, G908R, and 1007fs) associated with susceptibility to Crohn's disease were not found in these patients.	0.56	2005	NOD2	16	50712015	C	T
rs2066844	12019468	317	APAF1	umls:C0010346	BeFree	CARD15 is related to the NOD1/Apaf-1 family of apoptosis regulators, and three sequence variants (Arg702Trp, Gly908Arg, and Leu1007fsinsC) in the gene were demonstrated to be associated with CD.	0.000271442	2002	NOD2	16	50712015	C	T
rs2066844	20082483	55054	ATG16L1	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.367863153	2010	NOD2	16	50712015	C	T
rs2066844	18616576	64127	NOD2	umls:C0010346	BeFree	Granulomatous rosacea and Crohn's disease in a patient homozygous for the Crohn-associated NOD2/CARD15 polymorphism R702W.	0.56	2008	NOD2	16	50712015	C	T
rs2066844	18715515	6584	SLC22A5	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.079669474	2008	NOD2	16	50712015	C	T
rs2066844	14762777	64127	NOD2	umls:C0010346	BeFree	Sera from 303 patients were tested for antibodies to the Crohn's disease-related bacterial sequence (I2), anti-Escherichia coli outer membrane porin C, anti-Saccharomyces cerevisiae, and perinuclear antineutrophil cytoplasmic antibodies and for 3 Crohn's disease-associated variants of the NOD2 gene (R702W, G908R, and 1007fs) and compared with clinical data.	0.56	2004	NOD2	16	50712015	C	T
rs2066844	18715515	64127	NOD2	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.56	2008	NOD2	16	50712015	C	T
rs2066844	18715515	55054	ATG16L1	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.367863153	2008	NOD2	16	50712015	C	T
rs2066844	18715515	6583	SLC22A4	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.079659542	2008	NOD2	16	50712015	C	T
rs2066844	15785318	64127	NOD2	umls:C0010346	BeFree	Three common NOD2 mutations -- 3020insC, G908R and R702W -- have been shown to be associated with chronic inflammatory disease such as Crohn's disease, the 3020insC also with human malignancy colorectal cancer.	0.56	2005	NOD2	16	50712015	C	T
rs2066844	24345423	64127	NOD2	umls:C0010346	BeFree	Three NOD2 polymorphisms (single nucleotide polymorphism [SNP]8 [2104C>T, Arg702Trp], SNP12 [2722G>C, Gly908Arg], and SNP13 [3020insC, Leu1007 fsins C]), identified as disease-associated variants in Crohn's disease, have recently been suggested as gene markers of the outcome of hematopoietic stem cell transplantation (HSCT).	0.56	2013	NOD2	16	50712015	C	T
rs2066844	18680223	64127	NOD2	umls:C0010346	BeFree	To evaluate the role of genetic factors in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC), we investigated the single nucleotide polymorphisms (SNPs) of NOD2/CARD15 (R702W, G908R and L1007finsC), and Toll-like receptor 4 (TLR4) genes (D299G and T399I) in a selected inflammatory bowel disease (IBD) population coming from Southern Italy.	0.56	2008	NOD2	16	50712015	C	T
rs2066844	15168811	64127	NOD2	umls:C0010346	BeFree	CARD15 mutation analysis in an Italian population: Leu1007fsinsC but neither Arg702Trp nor Gly908Arg mutations are associated with Crohn's disease.	0.56	2004	NOD2	16	50712015	C	T
rs2066844	23892590	64127	NOD2	umls:C0010346	BeFree	Activation of NOD2 in HEK293 cells overexpressing NOD2 induced the IL-17C promoter, an activity that was significantly reduced in cells overexpressing the Crohn's disease-associated NOD2 mutation 3020insC (1007fs) or the Crohn's disease- and atopic dermatitis-associated NOD2-R702W variant.	0.56	2013	NOD2	16	50712015	C	T
rs2066844	19748964	64127	NOD2	umls:C0010346	BeFree	It has been shown previously that three nucleotide-binding oligomerization domain containing 2 (NOD2) variants (Arg702Trp, Gly908Arg and Lue1007fs) are associated with Crohn's disease (CD), a disorder clinically resembling Behçet's disease (BD).	0.56	2009	NOD2	16	50712015	C	T
rs2066844	23892590	27189	IL17C	umls:C0010346	BeFree	Activation of NOD2 in HEK293 cells overexpressing NOD2 induced the IL-17C promoter, an activity that was significantly reduced in cells overexpressing the Crohn's disease-associated NOD2 mutation 3020insC (1007fs) or the Crohn's disease- and atopic dermatitis-associated NOD2-R702W variant.	0.000814326	2013	NOD2	16	50712015	C	T
rs2066844	18680223	7099	TLR4	umls:C0010346	BeFree	To evaluate the role of genetic factors in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC), we investigated the single nucleotide polymorphisms (SNPs) of NOD2/CARD15 (R702W, G908R and L1007finsC), and Toll-like receptor 4 (TLR4) genes (D299G and T399I) in a selected inflammatory bowel disease (IBD) population coming from Southern Italy.	0.182842621	2008	NOD2	16	50712015	C	T
rs2066844	16485124	64127	NOD2	umls:C0010346	BeFree	We performed a limited DNA sequence analysis of the CARD15 gene in 89 patients with Crohn's disease (CD), 19 patients with ulcerative colitis (UC), and three patients with indeterminate colitis (IC), who were heterozygous carriers of one of the common CARD15 mutations [c.2104C>T (p.R702W), c.2722G>C (p.G908R), or c.3019_3020insC (p.Leu1007fsX1008)], the c.2462+10A>C variant, or of a new amino acid substitution in the 3'-end of exon 4.	0.56	2006	NOD2	16	50712015	C	T
rs2066844	15367194	64127	NOD2	umls:C0010346	BeFree	Two functional mutations, an insertion mutation at nucleotide 3020 (3020insC) and a missense mutation C2104T in the CARD15 gene (originally NOD2 gene) have been reported to be associated with Crohn's disease.	0.56	2004	NOD2	16	50712015	C	T
rs2066844	22543157	64127	NOD2	umls:C0010346	BeFree	Only two patients with early onset Crohn's disease exhibited rare deleterious variations within NOD2: the previously described R702W variant was the sole NOD2 variant in one patient, while the second patient also carried the L1007 frameshift insertion.	0.56	2013	NOD2	16	50712015	C	T
rs2066844	22289211	64127	NOD2	umls:C0010346	BeFree	Crohn's disease-associated NOD 2 variants (Arg702Trp and 3020insC) were found to be monomorphic (wild), and 7 subjects were heterozygous for Gly908Arg SNP in 263 patients with tuberculosis, 260 patients with leprosy and 270 healthy controls residing in northern Indian states.	0.56	2012	NOD2	16	50712015	C	T
rs2066844	12019468	10392	NOD1	umls:C0010346	BeFree	CARD15 is related to the NOD1/Apaf-1 family of apoptosis regulators, and three sequence variants (Arg702Trp, Gly908Arg, and Leu1007fsinsC) in the gene were demonstrated to be associated with CD.	0.017088363	2002	NOD2	16	50712015	C	T
rs2066844	17661913	64127	NOD2	umls:C0010346	BeFree	Genomic DNA from 563 individuals (Crohn's disease: n = 205; ulcerative colitis: n = 154; controls: n = 204) was analyzed for the presence of the SELS-105G>A polymorphism and the three nucleotide-binding oligomerization domain-containing protein 2 (NOD2)/caspase recruitment domain-containing protein 15 (CARD15) variants p.Arg702Trp, p.Gly908Arg and p.Leu1007fsX1008.	0.56	2007	NOD2	16	50712015	C	T
rs2066844	17174426	64127	NOD2	umls:C0010346	BeFree	In the current study, the frequency of CARD15/NOD2 gene variants (R702W, G908R, L1007fs), previously associated with Crohn's disease--a common inflammatory bowel disease, have been examined in a group of 308 sporadic PD patients and 220 healthy controls.	0.56	2007	NOD2	16	50712015	C	T
rs2066844	20646002	64127	NOD2	umls:C0010346	BeFree	Particular mutations of the NOD2 gene are associated with Crohn's disease including gly908arg, leu1007finsc and arg702trp polymorphisms.	0.56	2010	NOD2	16	50712015	C	T
rs2066845	17489054	64127	NOD2	umls:C0010346	BeFree	In the Dutch population, CARD15 G908R and L1007fs are associated with Crohn's disease.	0.56	2007	NOD2	16	50722629	G	C,T
rs2066845	12019468	317	APAF1	umls:C0010346	BeFree	CARD15 is related to the NOD1/Apaf-1 family of apoptosis regulators, and three sequence variants (Arg702Trp, Gly908Arg, and Leu1007fsinsC) in the gene were demonstrated to be associated with CD.	0.000271442	2002	NOD2	16	50722629	G	C,T
rs2066845	15168811	64127	NOD2	umls:C0010346	BeFree	CARD15 mutation analysis in an Italian population: Leu1007fsinsC but neither Arg702Trp nor Gly908Arg mutations are associated with Crohn's disease.	0.56	2004	NOD2	16	50722629	G	C,T
rs2066845	20082483	64127	NOD2	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.56	2010	NOD2	16	50722629	G	C,T
rs2066845	18942754	64127	NOD2	umls:C0010346	BeFree	Our aim was to investigate associations among IL1B-511, IL1B-31, IL1RN, TNFA-307, TLR-2, TLR-4, IL2-330, NOD2 G908R, NOD2 L1007fsinsC polymorphisms and both Crohn's disease (CD) and ulcerative colitis (UC) in a Brazilian population.	0.56	2009	NOD2	16	50722629	G	C,T
rs2066845	21690088	64127	NOD2	umls:C0010346	BeFree	We also show that the three main Crohn disease-associated mutants of NOD2 (1007fs, R702W, G908R) form an interaction with RIG-I and negatively regulate its signaling to a greater extent than wild-type NOD2.	0.56	2011	NOD2	16	50722629	G	C,T
rs2066845	17355968	64127	NOD2	umls:C0010346	BeFree	In this study, we demonstrate that membrane-bound versions of NOD2 and Crohn disease-associated mutants R702W and G908R are capable of responding to MDP and activating the NF-kappaB pathway from this location.	0.56	2007	NOD2	16	50722629	G	C,T
rs2066845	12019468	10392	NOD1	umls:C0010346	BeFree	CARD15 is related to the NOD1/Apaf-1 family of apoptosis regulators, and three sequence variants (Arg702Trp, Gly908Arg, and Leu1007fsinsC) in the gene were demonstrated to be associated with CD.	0.017088363	2002	NOD2	16	50722629	G	C,T
rs2066845	16133969	64127	NOD2	umls:C0010346	BeFree	Furthermore, the three main mutations of CARD15/NOD2 (R702W, G908R, and 1007fs) associated with susceptibility to Crohn's disease were not found in these patients.	0.56	2005	NOD2	16	50722629	G	C,T
rs2066845	17278126	64127	NOD2	umls:C0010346	BeFree	Role of ASCA and the NOD2/CARD15 mutation Gly908Arg in predicting increased surgical costs in Crohn's disease patients: a project of the European Collaborative Study Group on Inflammatory Bowel Disease.	0.56	2007	NOD2	16	50722629	G	C,T
rs2066845	15527324	64127	NOD2	umls:C0010346	BeFree	Three mutations (R702W, G908R, and 1007fs) within the CARD15 gene have been identified as independent risk factors for the development of Crohn's disease (CD).	0.56	2004	NOD2	16	50722629	G	C,T
rs2066845	15785318	64127	NOD2	umls:C0010346	BeFree	Three common NOD2 mutations -- 3020insC, G908R and R702W -- have been shown to be associated with chronic inflammatory disease such as Crohn's disease, the 3020insC also with human malignancy colorectal cancer.	0.56	2005	NOD2	16	50722629	G	C,T
rs2066845	17355968	19	ABCA1	umls:C0010346	BeFree	In this study, we demonstrate that membrane-bound versions of NOD2 and Crohn disease-associated mutants R702W and G908R are capable of responding to MDP and activating the NF-kappaB pathway from this location.	0.000542884	2007	NOD2	16	50722629	G	C,T
rs2066845	15202784	64127	NOD2	umls:C0010346	BeFree	A frameshift mutation (Leu1007fsinsC) and two missense mutations (Gly908Arg and Arg702Trp) in the NOD2/CARD15 gene are strongly associated with susceptibility to Crohn's disease.	0.56	2004	NOD2	16	50722629	G	C,T
rs2066845	12595906	64127	NOD2	umls:C0010346	BeFree	An insertion mutation at nucleotide 3020 (3020insC) and a missense mutation G2722C in the CARD15 gene on chromosome 16p have been reported to be associated with Crohn's disease (CD).	0.56	2003	NOD2	16	50722629	G	C,T
rs2066845	16485124	64127	NOD2	umls:C0010346	BeFree	We performed a limited DNA sequence analysis of the CARD15 gene in 89 patients with Crohn's disease (CD), 19 patients with ulcerative colitis (UC), and three patients with indeterminate colitis (IC), who were heterozygous carriers of one of the common CARD15 mutations [c.2104C>T (p.R702W), c.2722G>C (p.G908R), or c.3019_3020insC (p.Leu1007fsX1008)], the c.2462+10A>C variant, or of a new amino acid substitution in the 3'-end of exon 4.	0.56	2006	NOD2	16	50722629	G	C,T
rs2066845	20082483	149233	IL23R	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.370597435	2010	NOD2	16	50722629	G	C,T
rs2066845	18680223	7099	TLR4	umls:C0010346	BeFree	To evaluate the role of genetic factors in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC), we investigated the single nucleotide polymorphisms (SNPs) of NOD2/CARD15 (R702W, G908R and L1007finsC), and Toll-like receptor 4 (TLR4) genes (D299G and T399I) in a selected inflammatory bowel disease (IBD) population coming from Southern Italy.	0.182842621	2008	NOD2	16	50722629	G	C,T
rs2066845	22289211	64127	NOD2	umls:C0010346	BeFree	Crohn's disease-associated NOD 2 variants (Arg702Trp and 3020insC) were found to be monomorphic (wild), and 7 subjects were heterozygous for Gly908Arg SNP in 263 patients with tuberculosis, 260 patients with leprosy and 270 healthy controls residing in northern Indian states.	0.56	2012	NOD2	16	50722629	G	C,T
rs2066845	17174426	64127	NOD2	umls:C0010346	BeFree	In the current study, the frequency of CARD15/NOD2 gene variants (R702W, G908R, L1007fs), previously associated with Crohn's disease--a common inflammatory bowel disease, have been examined in a group of 308 sporadic PD patients and 220 healthy controls.	0.56	2007	NOD2	16	50722629	G	C,T
rs2066845	24345423	64127	NOD2	umls:C0010346	BeFree	Three NOD2 polymorphisms (single nucleotide polymorphism [SNP]8 [2104C>T, Arg702Trp], SNP12 [2722G>C, Gly908Arg], and SNP13 [3020insC, Leu1007 fsins C]), identified as disease-associated variants in Crohn's disease, have recently been suggested as gene markers of the outcome of hematopoietic stem cell transplantation (HSCT).	0.56	2013	NOD2	16	50722629	G	C,T
rs2066845	20646002	64127	NOD2	umls:C0010346	BeFree	Particular mutations of the NOD2 gene are associated with Crohn's disease including gly908arg, leu1007finsc and arg702trp polymorphisms.	0.56	2010	NOD2	16	50722629	G	C,T
rs2066845	17661913	64127	NOD2	umls:C0010346	BeFree	Genomic DNA from 563 individuals (Crohn's disease: n = 205; ulcerative colitis: n = 154; controls: n = 204) was analyzed for the presence of the SELS-105G>A polymorphism and the three nucleotide-binding oligomerization domain-containing protein 2 (NOD2)/caspase recruitment domain-containing protein 15 (CARD15) variants p.Arg702Trp, p.Gly908Arg and p.Leu1007fsX1008.	0.56	2007	NOD2	16	50722629	G	C,T
rs2066845	23709157	64127	NOD2	umls:C0010346	BeFree	Three common NOD2 mutations are associated with Crohn's disease (p=5.08×10(-7), 1.67×10(-6), and 1.87×10(-2) for 1007fs, R720W, and G908R, respectively), but not with ulcerative colitis (p=0.1046, 0.1269, and 0.8929, respectively).	0.56	2013	NOD2	16	50722629	G	C,T
rs2066845	12115195	64127	NOD2	umls:C0010346	BeFree	A case-control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro(268)Ser, Arg(702)Trp, Gly(908)Arg, and Leu(1007)fsinsC) was performed in 229 cases of primary AS with no diagnosed inflammatory bowel disease (IBD), 197 cases of AS associated with IBD (referred to as colitic spondylarthritis; comprising 78 with CD and 119 with ulcerative colitis [UC]), and 229 ethnically matched, healthy controls.	0.56	2002	NOD2	16	50722629	G	C,T
rs2066845	18680223	64127	NOD2	umls:C0010346	BeFree	To evaluate the role of genetic factors in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC), we investigated the single nucleotide polymorphisms (SNPs) of NOD2/CARD15 (R702W, G908R and L1007finsC), and Toll-like receptor 4 (TLR4) genes (D299G and T399I) in a selected inflammatory bowel disease (IBD) population coming from Southern Italy.	0.56	2008	NOD2	16	50722629	G	C,T
rs2066845	19570052	64127	NOD2	umls:C0010346	BeFree	NOD2/CARD15 is involved in the innate immune response and three polymorphisms in this gene (Arg702Trp rs2066844, Gly908Arg rs2066845 and Leu1007fsinsC rs5743293) have been associated with risk of the rare Crohn's disease.	0.56	2010	NOD2	16	50722629	G	C,T
rs2066845	14762777	64127	NOD2	umls:C0010346	BeFree	Sera from 303 patients were tested for antibodies to the Crohn's disease-related bacterial sequence (I2), anti-Escherichia coli outer membrane porin C, anti-Saccharomyces cerevisiae, and perinuclear antineutrophil cytoplasmic antibodies and for 3 Crohn's disease-associated variants of the NOD2 gene (R702W, G908R, and 1007fs) and compared with clinical data.	0.56	2004	NOD2	16	50722629	G	C,T
rs2066845	19748964	64127	NOD2	umls:C0010346	BeFree	It has been shown previously that three nucleotide-binding oligomerization domain containing 2 (NOD2) variants (Arg702Trp, Gly908Arg and Lue1007fs) are associated with Crohn's disease (CD), a disorder clinically resembling Behçet's disease (BD).	0.56	2009	NOD2	16	50722629	G	C,T
rs2066845	20082483	55054	ATG16L1	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.367863153	2010	NOD2	16	50722629	G	C,T
rs2066847	25365249	64127	NOD2	umls:C0010346	BeFree	The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067.	0.56	2014	NOD2	16	50729867	-	C
rs2066847	23128233	64127	NOD2	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.56	2012	NOD2	16	50729867	-	C
rs2066847	20082483	149233	IL23R	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.370597435	2010	NOD2	16	50729867	-	C
rs2066847	18587394	64127	NOD2	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.56	2008	NOD2	16	50729867	-	C
rs2066847	20570966	64127	NOD2	umls:C0010346	GWASCAT	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	0.56	2010	NOD2	16	50729867	-	C
rs2066847	20082483	64127	NOD2	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.56	2010	NOD2	16	50729867	-	C
rs2066847	25365249	2309	FOXO3	umls:C0010346	BeFree	The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067.	0.000814326	2014	NOD2	16	50729867	-	C
rs2066847	20082483	55054	ATG16L1	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.367863153	2010	NOD2	16	50729867	-	C
rs2075820	17964870	10392	NOD1	umls:C0010346	BeFree	NOD1 gene E266K polymorphism is associated with disease susceptibility but not with disease phenotype or NOD2/CARD15 in Hungarian patients with Crohn's disease.	0.017088363	2007	NOD1	7	30452621	C	T
rs2075820	17964870	64127	NOD2	umls:C0010346	BeFree	NOD1 gene E266K polymorphism is associated with disease susceptibility but not with disease phenotype or NOD2/CARD15 in Hungarian patients with Crohn's disease.	0.56	2007	NOD1	7	30452621	C	T
rs2076756	22936669	64127	NOD2	umls:C0010346	GWASCAT	A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.	0.56	2013	NOD2	16	50722970	A	G
rs2076756	21209938	64127	NOD2	umls:C0010346	BeFree	The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.	0.56	2010	NOD2	16	50722970	A	G
rs2076756	21102463	64127	NOD2	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.56	2010	NOD2	16	50722970	A	G
rs2076756	22412388	64127	NOD2	umls:C0010346	GWASCAT	In all, the 16 replicated and newly discovered loci, in addition to the three coding NOD2 variants, accounted for 11.2% of the total genetic variance for CD risk in the AJ population.	0.56	2012	NOD2	16	50722970	A	G
rs2076756	17435756	64127	NOD2	umls:C0010346	GWASCAT	Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.	0.56	2007	NOD2	16	50722970	A	G
rs2076756	17684544	64127	NOD2	umls:C0010346	GWASCAT	Among the 116,161 single-nucleotide polymorphisms tested, an association with the known CD susceptibility gene NOD2, the 5q31 haplotype, and the recently reported CD locus at 5p13.1 was confirmed.	0.56	2007	NOD2	16	50722970	A	G
rs208294	17257221	5027	P2RX7	umls:C0010346	BeFree	Functional P2X7 receptor polymorphisms (His155Tyr, Arg307Gln, Glu496Ala) in patients with Crohn's disease.	0.000814326	2007	P2RX7;LOC105370032	12	121162450	T	G,C,A
rs212388	21102463	117289	TAGAP	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.123181358	2010	NA	6	159069404	C	T
rs2149085	23850713	8635	RNASET2	umls:C0010346	GWASCAT	Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.	0.122367032	2014	RNASET2	6	166957622	T	C
rs2165047	17476680	9231	DLG5	umls:C0010346	GAD	[Polymorphisms 3020insC in CARD15 and SNP rs3792876 in SLC22A4/5 occurred statistically significantly more often in patients with pediatric-onset CD than in patients with adult-onset CD. Polymorphisms 3020insC in CARD15 and SNP rs2165047 in DLG5 were assoc]	0.057008977	2007	DLG5	10	77791882	C	T
rs2188962	18587394	441108	C5orf56	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.127101096	2008	C5orf56	5	132435113	C	T
rs2188962	20570966	441108	C5orf56	umls:C0010346	GWASCAT	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	0.127101096	2010	C5orf56	5	132435113	C	T
rs2188962	18587394	441108	C5orf56	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.127101096	2008	C5orf56	5	132435113	C	T
rs2188962	20570966	441108	C5orf56	umls:C0010346	GAD	[Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.]	0.127101096	2010	C5orf56	5	132435113	C	T
rs2201841	20066736	64127	NOD2	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.56	2010	IL23R	1	67228519	A	G
rs2201841	20066736	55054	ATG16L1	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.367863153	2010	IL23R	1	67228519	A	G
rs2201841	20066736	50941	IBD5	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.049616576	2010	IL23R	1	67228519	A	G
rs2201841	20066736	149233	IL23R	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.370597435	2010	IL23R	1	67228519	A	G
rs2201841	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67228519	A	G
rs2229113	12759436	3587	IL10RA	umls:C0010346	BeFree	We decided to screen for mutations of the IL-10R1 cDNA in healthy volunteers and Crohn's disease patients and identified two novel variants: a serine 138-to-glycine (S138G) and a glycine 330-to-arginine (G330R) substitution.	0.001085767	2003	IL10RA	11	117998955	A	G
rs224136	17435756	22891	ZNF365	umls:C0010346	GAD	[Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.]	0.137383549	2007	NA	10	62710915	C	T
rs224136	19262523	4689	NCF4	umls:C0010346	BeFree	rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population.	0.128544182	2009	NA	10	62710915	C	T
rs224136	19262523	8929	PHOX2B	umls:C0010346	BeFree	rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population.	0.128186863	2009	NA	10	62710915	C	T
rs224136	19262523	339145	FAM92B	umls:C0010346	BeFree	rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population.	0.12554839	2009	NA	10	62710915	C	T
rs224143	25489960	29761	USP25	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.002638474	2015	NA	10	62718076	G	A
rs224143	25489960	5771	PTPN2	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.269023212	2015	NA	10	62718076	G	A
rs224143	25489960	22891	ZNF365	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.137383549	2015	NA	10	62718076	G	A
rs224143	25489960	159296	NKX2-3	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.274386036	2015	NA	10	62718076	G	A
rs224143	25489960	57178	ZMIZ1	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.125005506	2015	NA	10	62718076	G	A
rs224143	25489960	2859	GPR35	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.000271442	2015	NA	10	62718076	G	A
rs2241879	18162085	55054	ATG16L1	umls:C0010346	BeFree	The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.	0.367863153	2008	ATG16L1;SCARNA5	2	233274822	G	A
rs2241880	20082483	149233	IL23R	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.370597435	2010	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	17894849	55054	ATG16L1	umls:C0010346	BeFree	IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease.	0.367863153	2007	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	25159710	55054	ATG16L1	umls:C0010346	BeFree	However a possible role of ATG16L1 (T300A) on CD phenotype was suggested.	0.367863153	2014	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	22412388	55054	ATG16L1	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.367863153	2012	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	20066736	149233	IL23R	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.370597435	2010	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	19659808	55054	ATG16L1	umls:C0010346	BeFree	Genome-wide association studies have described an association of the ATG16L1 (autophagy 16-like 1) gene rs2241880 variant with Crohn's disease (CD).	0.367863153	2009	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	18715515	6584	SLC22A5	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.079669474	2008	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	24522266	3593	IL12B	umls:C0010346	BeFree	Detection of Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease is unrelated to the presence of single nucleotide polymorphisms rs2241880 (ATG16L1) and rs10045431 (IL12B).	0.144832032	2014	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	24522266	55054	ATG16L1	umls:C0010346	BeFree	Detection of Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease is unrelated to the presence of single nucleotide polymorphisms rs2241880 (ATG16L1) and rs10045431 (IL12B).	0.367863153	2014	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	19491842	345611	IRGM	umls:C0010346	BeFree	The aim of this study was to determine the role of the ATG16L1 (rs2241880) and IRGM (rs13361189 and rs4958847) genes polymorphism in Crohn's disease (CD) and ulcerative colitis (UC).	0.17026908	2009	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	20066736	55054	ATG16L1	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.367863153	2010	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	18715515	64127	NOD2	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.56	2008	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	17200669	64127	NOD2	umls:C0010346	BeFree	We found a statistically significant interaction with respect to Crohn disease risk between rs2241880 and the established CARD15 susceptibility variants (P = 0.039).	0.56	2007	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	20066736	64127	NOD2	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.56	2010	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	18715515	55054	ATG16L1	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.367863153	2008	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	20222171	55054	ATG16L1	umls:C0010346	BeFree	Publications addressing the relationship between rs2241880/T300A polymorphism of ATG16L1 and Crohn's disease (CD) and ulcerative colitis (UC) were selected from the MEDLINE and EMBASE databases.	0.367863153	2010	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	19491842	55054	ATG16L1	umls:C0010346	BeFree	The aim of this study was to determine the role of the ATG16L1 (rs2241880) and IRGM (rs13361189 and rs4958847) genes polymorphism in Crohn's disease (CD) and ulcerative colitis (UC).	0.367863153	2009	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	17894849	149233	IL23R	umls:C0010346	BeFree	IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease.	0.370597435	2007	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	20082483	55054	ATG16L1	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.367863153	2010	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	19575361	55054	ATG16L1	umls:C0010346	BeFree	Thr300Ala polymorphism in ATG16L1 was reported as a susceptibility factor to Crohn's disease (CD).	0.367863153	2009	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	20082483	64127	NOD2	umls:C0010346	BeFree	One hundred and eighty unrelated IBD patients [57 Crohn's disease (CD) and 123 ulcerative colitis (UC)] and 186 healthy controls were genotyped for the following known genetic susceptibility variants: NOD2 - Arg702Trp (rs2066844), Gly908Arg (rs2066845) and Leu1007insC (rs2066847), as well as IL23R - Arg381Gln (rs11209026) and ATG16L1 - Thr300Ala (rs2241880).	0.56	2010	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	18162085	55054	ATG16L1	umls:C0010346	BeFree	The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.	0.367863153	2008	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	22412388	677775	SCARNA5	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.12	2012	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	17435756	677775	SCARNA5	umls:C0010346	GWASCAT	Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.	0.12	2007	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	20066736	50941	IBD5	umls:C0010346	BeFree	To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.	0.049616576	2010	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	19337756	55054	ATG16L1	umls:C0010346	BeFree	ATG16L1 T300A polymorphism and Crohn's disease susceptibility: evidence from 13,022 cases and 17,532 controls.	0.367863153	2009	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	24022642	55054	ATG16L1	umls:C0010346	BeFree	T300A variant of autophagy ATG16L1 gene is associated with decreased antigen sampling and processing by dendritic cells in pediatric Crohn's disease.	0.367863153	2014	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	18715515	6583	SLC22A4	umls:C0010346	BeFree	We confirmed a strong association between three NOD2/CARD15 gene variants (Pro268Ser, OR = 2.52, 95% CI = 1.34-4.75); (Arg702Trp, OR = 6.65, 95% CI = 1.99-22.17); (1007fs, OR = 9.59, 95% CI = 3.94-23.29), and a weak association between both the protective OCTN1/OCTN2 CC haplotype (OR = 0.28, 95% CI = 0.08-0.94), and a variant of ATG16L1 gene (Thr300Ala, OR = 0.468, 95% CI = 0.24-0.90) with Crohn's disease.	0.079659542	2008	ATG16L1;SCARNA5	2	233274722	A	G
rs2241880	17435756	55054	ATG16L1	umls:C0010346	GWASCAT	Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.	0.367863153	2007	ATG16L1;SCARNA5	2	233274722	A	G
rs2249296	25557950	9635	CLCA2	umls:C0010346	GWASCAT	Identification of risk loci for Crohn's disease phenotypes using a genome-wide association study.	0.12	2014	CLCA2	1	86444581	T	C
rs2274910	18587394	55600	ITLN1	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.129825446	2008	ITLN1	1	160882256	T	C
rs2274910	18587394	55600	ITLN1	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.129825446	2008	ITLN1	1	160882256	T	C
rs2275913	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	IL17A	6	52186235	G	A
rs2275913	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	IL17A	6	52186235	G	A
rs2275913	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	IL17A	6	52186235	G	A
rs2275913	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	IL17A	6	52186235	G	A
rs2275913	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	IL17A	6	52186235	G	A
rs2275913	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	IL17A	6	52186235	G	A
rs2275913	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	IL17A	6	52186235	G	A
rs2275913	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	IL17A	6	52186235	G	A
rs2275913	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	IL17A	6	52186235	G	A
rs2275913	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	IL17A	6	52186235	G	A
rs2275913	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	IL17A	6	52186235	G	A
rs2275913	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	IL17A	6	52186235	G	A
rs2276707	21830270	8856	NR1I2	umls:C0010346	BeFree	Genomic DNA from 2823 individuals of Caucasian origin including 859 patients with Crohn's disease (CD), 464 patients with ulcerative colitis (UC), and 1500 healthy, unrelated controls was analyzed for eight PXR/NR1I2 single nucleotide polymorphisms (SNPs) (rs12721602 (-25564), rs3814055 (-25385), rs1523128 (-24756), rs1523127 (-24381), rs45610735 = p.Gly36Arg (+106), rs6785049 (+7635), rs2276707 (+8055), and rs3814057 (+11156)).	0.006991475	2011	NR1I2	3	119815306	C	G,T
rs2277680	18248772	58191	CXCL16	umls:C0010346	BeFree	In this study, we demonstrate that in Crohn's disease (CD), the CXCL16 p.Ala181Val polymorphism is not a disease susceptibility gene but associated with younger age at disease onset (p=0.016) and higher frequency of ileal involvement (p=0.024; OR 2.17; 95% CI 1.12-4.21) in ValVal carriers compared to a higher frequency of colonic involvement in AlaAla carriers (p=0.009; OR 2.60; CI 1.29-5.25).	0.003267234	2008	CXCL16	17	4735268	G	A
rs2284553	23128233	3460	IFNGR2	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12	2012	IFNGR2	21	33404389	A	G
rs2301436	20570966	11116	FGFR1OP	umls:C0010346	GWASCAT	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	0.127101096	2010	FGFR1OP	6	167024500	C	T
rs2301436	18587394	11116	FGFR1OP	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.127101096	2008	FGFR1OP	6	167024500	C	T
rs2301436	20570966	11116	FGFR1OP	umls:C0010346	GAD	[Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.]	0.127101096	2010	FGFR1OP	6	167024500	C	T
rs2301436	18587394	1235	CCR6	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.007915422	2008	FGFR1OP	6	167024500	C	T
rs2301436	18587394	11116	FGFR1OP	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.127101096	2008	FGFR1OP	6	167024500	C	T
rs2413583	21102463	5155	PDGFB	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.002367032	2010	NA	22	39263768	C	T
rs2430561	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	IFNG	12	68158742	T	A
rs2430561	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	IFNG	12	68158742	T	A
rs2430561	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	IFNG	12	68158742	T	A
rs2430561	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	IFNG	12	68158742	T	A
rs2430561	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	IFNG	12	68158742	T	A
rs2430561	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	IFNG	12	68158742	T	A
rs2430561	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	IFNG	12	68158742	T	A
rs2430561	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	IFNG	12	68158742	T	A
rs2430561	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	IFNG	12	68158742	T	A
rs2430561	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	IFNG	12	68158742	T	A
rs2430561	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	IFNG	12	68158742	T	A
rs2430561	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	IFNG	12	68158742	T	A
rs2476601	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	23913970	26191	PTPN22	umls:C0010346	BeFree	Our data not only demonstrate a critical role of PTPN22 in regulating macrophage polarization but also provide a molecular explanation for the protective effect of the C1858T SNP in Crohn's disease.	0.153757276	2013	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	24971461	26191	PTPN22	umls:C0010346	BeFree	After Bonferroni correction for multiple testing, both the homozygous and the heterozygous variant genotypes of IL23R G>A(rs11209026) (OR(CD,adj): 0.38, 95% CI: 0.21-0.67, p = 0.03; OR(IBD,adj) 0.43, 95% CI: 0.28-0.67, p = 0.007) and PTPN22 1858 G>A(rs2476601) (OR(CD,unadj) 0.54, 95% CI: 0.41-0.72, p = 7*10-4; OR(IBD,unadj): 0.61, 95% CI: 0.48-0.77, p = 0.001) were associated with reduced risk of CD.	0.153757276	2014	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	16391555	26191	PTPN22	umls:C0010346	GAD	[Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis.]	0.153757276	2006	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	21102463	26191	PTPN22	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.153757276	2010	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	18587394	26191	PTPN22	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.153757276	2008	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	24971461	149233	IL23R	umls:C0010346	BeFree	After Bonferroni correction for multiple testing, both the homozygous and the heterozygous variant genotypes of IL23R G>A(rs11209026) (OR(CD,adj): 0.38, 95% CI: 0.21-0.67, p = 0.03; OR(IBD,adj) 0.43, 95% CI: 0.28-0.67, p = 0.007) and PTPN22 1858 G>A(rs2476601) (OR(CD,unadj) 0.54, 95% CI: 0.41-0.72, p = 7*10-4; OR(IBD,unadj): 0.61, 95% CI: 0.48-0.77, p = 0.001) were associated with reduced risk of CD.	0.370597435	2014	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2542151	17554300	56984	PSMG2	umls:C0010346	GAD	[Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.]	0.007101096	2007	NA	18	12779948	G	T
rs2542151	17554261	56984	PSMG2	umls:C0010346	GAD	[Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.]	0.007101096	2007	NA	18	12779948	G	T
rs2542151	18587394	56984	PSMG2	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.007101096	2008	NA	18	12779948	G	T
rs2549794	21102463	64167	ERAP2	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.242367032	2010	ERAP1;ERAP2	5	96908845	C	T
rs2549794	21102463	64167	ERAP2	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.242367032	2010	ERAP1;ERAP2	5	96908845	C	T
rs2569190	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	CD14;TMCO6	5	140633331	A	G
rs2569190	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	CD14;TMCO6	5	140633331	A	G
rs2631367	16361305	6584	SLC22A5	umls:C0010346	BeFree	Genetic association between Crohn's disease (CD) and OCTN1 (SLC22A4) C1672T/OCTN2 (SLC22A5) G-207C variants in IBD5 has recently been reported.	0.079669474	2006	SLC22A5;LOC553103	5	132369766	C	G
rs2631367	16361305	6583	SLC22A4	umls:C0010346	BeFree	Genetic association between Crohn's disease (CD) and OCTN1 (SLC22A4) C1672T/OCTN2 (SLC22A5) G-207C variants in IBD5 has recently been reported.	0.079659542	2006	SLC22A5;LOC553103	5	132369766	C	G
rs2631367	21279723	6583	SLC22A4	umls:C0010346	BeFree	To evaluate the association of the IBD5 locus to the predisposition of inflammatory bowel diseases (IBDs), a series of meta-analyses between five IBD5 variants (OCTN1 C1672T, OCTN2 G-207C, OCTN1/2 TC haplotype, IGR2096a_1, IGR2198a_1 and IGR2230a_1) and Crohn's disease (CD) and ulcerative colitis (UC) were performed, which included a total of 26 studies.	0.079659542	2011	SLC22A5;LOC553103	5	132369766	C	G
rs2631367	17391561	6583	SLC22A4	umls:C0010346	BeFree	Plasma carnitine ester profiles in Crohn's disease patients characterized for SLC22A4 C1672T and SLC22A5 G-207C genotypes.	0.079659542	2007	SLC22A5;LOC553103	5	132369766	C	G
rs2631367	17391561	6584	SLC22A5	umls:C0010346	BeFree	Plasma carnitine ester profiles in Crohn's disease patients characterized for SLC22A4 C1672T and SLC22A5 G-207C genotypes.	0.079669474	2007	SLC22A5;LOC553103	5	132369766	C	G
rs2631367	16361305	50941	IBD5	umls:C0010346	BeFree	Genetic association between Crohn's disease (CD) and OCTN1 (SLC22A4) C1672T/OCTN2 (SLC22A5) G-207C variants in IBD5 has recently been reported.	0.049616576	2006	SLC22A5;LOC553103	5	132369766	C	G
rs2631367	21279723	6584	SLC22A5	umls:C0010346	BeFree	To evaluate the association of the IBD5 locus to the predisposition of inflammatory bowel diseases (IBDs), a series of meta-analyses between five IBD5 variants (OCTN1 C1672T, OCTN2 G-207C, OCTN1/2 TC haplotype, IGR2096a_1, IGR2198a_1 and IGR2230a_1) and Crohn's disease (CD) and ulcerative colitis (UC) were performed, which included a total of 26 studies.	0.079669474	2011	SLC22A5;LOC553103	5	132369766	C	G
rs2631367	21279723	50941	IBD5	umls:C0010346	BeFree	To evaluate the association of the IBD5 locus to the predisposition of inflammatory bowel diseases (IBDs), a series of meta-analyses between five IBD5 variants (OCTN1 C1672T, OCTN2 G-207C, OCTN1/2 TC haplotype, IGR2096a_1, IGR2198a_1 and IGR2230a_1) and Crohn's disease (CD) and ulcerative colitis (UC) were performed, which included a total of 26 studies.	0.049616576	2011	SLC22A5;LOC553103	5	132369766	C	G
rs2695121	21245992	4790	NFKB1	umls:C0010346	BeFree	Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.	0.008262808	2011	NR1H2	19	50377484	T	C
rs2695121	21245992	8856	NR1I2	umls:C0010346	BeFree	Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.	0.006991475	2011	NR1H2	19	50377484	T	C
rs2797685	21102463	8863	PER3	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.122367032	2010	PER3	1	7819003	C	T
rs2797685	21102463	8863	PER3	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.122367032	2010	PER3	1	7819003	C	T
rs2823256	25489960	29761	USP25	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.002638474	2015	LOC101927745	21	15412387	G	A
rs2823256	25489960	5771	PTPN2	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.269023212	2015	LOC101927745	21	15412387	G	A
rs2823256	25489960	57178	ZMIZ1	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.125005506	2015	LOC101927745	21	15412387	G	A
rs2823256	25489960	22891	ZNF365	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.137383549	2015	LOC101927745	21	15412387	G	A
rs2823256	25489960	2859	GPR35	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.000271442	2015	LOC101927745	21	15412387	G	A
rs2823256	25489960	159296	NKX2-3	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.274386036	2015	LOC101927745	21	15412387	G	A
rs2834215	22936669	3460	IFNGR2	umls:C0010346	GWASCAT	We also found suggestive evidence for the association of the IFNGR2 (21q22.11), FOXP2 (7q31), MACROD2 (20p12.1) and AIF1 (6p21.3) loci with CD risk.	0.12	2013	IFNGR2	21	33424579	A	G
rs28360457	17257221	5027	P2RX7	umls:C0010346	BeFree	Functional P2X7 receptor polymorphisms (His155Tyr, Arg307Gln, Glu496Ala) in patients with Crohn's disease.	0.000814326	2007	P2RX7;LOC105370032	12	121175426	G	A
rs28362491	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	NFKB1;LOC105377621	4	102500998	ATTG	-
rs28362491	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	NFKB1;LOC105377621	4	102500998	ATTG	-
rs28362491	21245992	8856	NR1I2	umls:C0010346	BeFree	Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.	0.006991475	2011	NFKB1;LOC105377621	4	102500998	ATTG	-
rs28362491	21245992	4790	NFKB1	umls:C0010346	BeFree	Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.	0.008262808	2011	NFKB1;LOC105377621	4	102500998	ATTG	-
rs28362491	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	NFKB1;LOC105377621	4	102500998	ATTG	-
rs2838519	21102463	8209	C21orf33	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.122367032	2010	LOC105377139	21	44195140	G	A
rs2872507	18587394	124626	ZPBP2	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.002367032	2008	NA	17	39884510	G	A
rs2872507	18587394	94103	ORMDL3	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.005276948	2008	NA	17	39884510	G	A
rs2872507	22694930	55876	GSDMB	umls:C0010346	BeFree	The minor allele A of rs2872507 in GSDMB is the protective allele for asthma but the risk allele for rheumatoid arthritis, Crohn disease, and ulcerative colitis.	0.007372538	2012	NA	17	39884510	G	A
rs2902440	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67205233	G	A
rs2945412	23128233	8844	KSR1	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12	2012	KSR1	17	27516617	G	A
rs3024505	20509889	3586	IL10	umls:C0010346	GAD	[The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study.]	0.165525085	2010	NA	1	206766559	G	A
rs3024505	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	NA	1	206766559	G	A
rs3024505	20509889	3586	IL10	umls:C0010346	BeFree	The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study.	0.165525085	2010	NA	1	206766559	G	A
rs3024505	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	NA	1	206766559	G	A
rs3024505	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	NA	1	206766559	G	A
rs3091315	21102463	6347	CCL2	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.135559401	2010	NA	17	34266646	A	G
rs3091316	22412388	6347	CCL2	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.135559401	2012	NA	17	34266955	G	A
rs3091338	22412388	3562	IL3	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.002367032	2012	NA	5	132067045	C	T
rs3094188	23266558	100130889	PSORS1C3	umls:C0010346	GWASCAT	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	0.12	2013	PSORS1C3	6	31174468	C	A
rs3135932	12759436	3587	IL10RA	umls:C0010346	BeFree	We decided to screen for mutations of the IL-10R1 cDNA in healthy volunteers and Crohn's disease patients and identified two novel variants: a serine 138-to-glycine (S138G) and a glycine 330-to-arginine (G330R) substitution.	0.001085767	2003	IL10RA	11	117993348	A	G
rs3180018	21102463	10067	SCAMP3	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.122367032	2010	NA	NA	NA	NA	NA
rs3197999	18587394	4485	MST1	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.255830843	2008	MST1	3	49684099	G	A
rs3197999	21102463	4485	MST1	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.255830843	2010	MST1	3	49684099	G	A
rs3197999	18587394	4485	MST1	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.255830843	2008	MST1	3	49684099	G	A
rs3197999	22087277	4485	MST1	umls:C0010346	BeFree	Protein characterization of a candidate mechanism SNP for Crohn's disease: the macrophage stimulating protein R689C substitution.	0.255830843	2011	MST1	3	49684099	G	A
rs324420	19053981	2166	FAAH	umls:C0010346	BeFree	To analyse FAAH expression and the FAAH 385 C/A (p.Pro129Thr; rs324420) single nucleotide polymorphism (SNP) in-patients with Crohn's disease (CD) and ulcerative colitis (UC).	0.002909916	2009	FAAH	1	46405089	C	A
rs324420	18493729	2166	FAAH	umls:C0010346	BeFree	Genomic DNA from 202 patients with Crohn's disease (CD) and 206 healthy controls was analyzed for the C385A polymorphism in the FAAH gene to address a possible role in humans.	0.002909916	2008	FAAH	1	46405089	C	A
rs352139	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	TLR9	3	52224356	T	C
rs352139	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	TLR9	3	52224356	T	C
rs352139	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	TLR9	3	52224356	T	C
rs352139	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	TLR9	3	52224356	T	C
rs352139	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	TLR9	3	52224356	T	C
rs352139	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR9	3	52224356	T	C
rs352139	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	TLR9	3	52224356	T	C
rs352139	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	TLR9	3	52224356	T	C
rs352139	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	TLR9	3	52224356	T	C
rs352139	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	TLR9	3	52224356	T	C
rs352139	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR9	3	52224356	T	C
rs352139	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	TLR9	3	52224356	T	C
rs352139	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	TLR9	3	52224356	T	C
rs352139	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	TLR9	3	52224356	T	C
rs352139	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	TLR9	3	52224356	T	C
rs35829419	20182451	22900	CARD8	umls:C0010346	BeFree	Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease.	0.008544182	2010	NLRP3	1	247425556	C	A
rs35829419	20182451	114548	NLRP3	umls:C0010346	GAD	[Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease.]	0.140812605	2010	NLRP3	1	247425556	C	A
rs35829419	20182451	114548	NLRP3	umls:C0010346	BeFree	Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease.	0.140812605	2010	NLRP3	1	247425556	C	A
rs35829419	20182451	64127	NOD2	umls:C0010346	BeFree	We found that the presence of the minor allele of rs2043211 with the major allele of rs35829419 conferred a protective effect against Crohn's disease (and vice versa), which intensified in the absence of NOD2 mutations (P(1,2/1,1)=0.009, odds ratio (OR)=0.66, 95% confidence interval (CI) (0.48-0.90); P(1,1/1,2)=0.015, OR=0.35, 95% CI (0.15-0.82)).	0.56	2010	NLRP3	1	247425556	C	A
rs35873774	18775308	7495	XBP1P1	umls:C0010346	BeFree	An association of XBP1 variants with both forms of human IBD (Crohn's disease and ulcerative colitis) was identified and replicated (rs35873774; p value 1.6 x 10(-5)) with novel, private hypomorphic variants identified as susceptibility factors.	0.001085767	2008	XBP1	22	28795944	A	G
rs359457	21102463	91272	BOD1	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.002367032	2010	NA	5	173852839	C	T
rs361525	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	TNF	6	31575324	G	A
rs361525	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	TNF	6	31575324	G	A
rs361525	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TNF	6	31575324	G	A
rs361525	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	TNF	6	31575324	G	A
rs361525	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	TNF	6	31575324	G	A
rs361525	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	TNF	6	31575324	G	A
rs361525	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	TNF	6	31575324	G	A
rs361525	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	TNF	6	31575324	G	A
rs361525	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TNF	6	31575324	G	A
rs361525	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	TNF	6	31575324	G	A
rs361525	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	TNF	6	31575324	G	A
rs361525	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	TNF	6	31575324	G	A
rs371209985	23709157	64127	NOD2	umls:C0010346	BeFree	Three common NOD2 mutations are associated with Crohn's disease (p=5.08×10(-7), 1.67×10(-6), and 1.87×10(-2) for 1007fs, R720W, and G908R, respectively), but not with ulcerative colitis (p=0.1046, 0.1269, and 0.8929, respectively).	0.56	2013	WDHD1	14	54957612	C	T
rs3732378	16405540	1524	CX3CR1	umls:C0010346	BeFree	Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype.	0.005905708	2006	CX3CR1	3	39265671	G	A
rs3732378	18617779	64127	NOD2	umls:C0010346	BeFree	Our aim was to evaluate the frequency of CX3CR1 V249I and T280M polymorphisms and NOD2/CARD15 mutations in Crohn's disease patients and to search for a relationship with phenotype.	0.56	2008	CX3CR1	3	39265671	G	A
rs3732379	18617779	1524	CX3CR1	umls:C0010346	BeFree	The V249I polymorphism of the CX3CR1 gene is associated with fibrostenotic disease behavior in patients with Crohn's disease.	0.005905708	2008	CX3CR1	3	39265765	C	T
rs3732379	18617779	64127	NOD2	umls:C0010346	BeFree	Our aim was to evaluate the frequency of CX3CR1 V249I and T280M polymorphisms and NOD2/CARD15 mutations in Crohn's disease patients and to search for a relationship with phenotype.	0.56	2008	CX3CR1	3	39265765	C	T
rs3749172	25489960	5771	PTPN2	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.269023212	2015	GPR35	2	240630832	A	C,T
rs3749172	25489960	29761	USP25	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.002638474	2015	GPR35	2	240630832	A	C,T
rs3749172	25489960	22891	ZNF365	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.137383549	2015	GPR35	2	240630832	A	C,T
rs3749172	25489960	159296	NKX2-3	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.274386036	2015	GPR35	2	240630832	A	C,T
rs3749172	25489960	57178	ZMIZ1	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.125005506	2015	GPR35	2	240630832	A	C,T
rs3749172	25489960	2859	GPR35	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.000271442	2015	GPR35	2	240630832	A	C,T
rs3751143	17257221	5027	P2RX7	umls:C0010346	BeFree	Functional P2X7 receptor polymorphisms (His155Tyr, Arg307Gln, Glu496Ala) in patients with Crohn's disease.	0.000814326	2007	P2RX7;LOC105370032	12	121184501	A	C
rs376377228	18088064	149233	IL23R	umls:C0010346	BeFree	Given the association of IL23R with inflammatory bowel disease (IBD), we characterized the role of IL-17F in IBD including its intestinal gene expression and the effect of the IL17F p.His161Arg polymorphism on disease susceptibility and phenotype of Crohn's disease (CD) and ulcerative colitis (UC).	0.370597435	2008	IL23R	1	67182950	A	G
rs3764147	18587394	144811	LACC1	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.12973957	2008	LACC1	13	43883789	A	G
rs3764147	18587394	144811	LACC1	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.12973957	2008	LACC1	13	43883789	A	G
rs3764147	21102463	144811	LACC1	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.12973957	2010	LACC1	13	43883789	A	G
rs3764147	23128233	144811	LACC1	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12973957	2012	LACC1	13	43883789	A	G
rs3792109	22936669	677775	SCARNA5	umls:C0010346	GWASCAT	A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.	0.12	2013	ATG16L1;SCARNA5	2	233275771	G	A
rs3792109	21102463	55054	ATG16L1	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.367863153	2010	ATG16L1;SCARNA5	2	233275771	G	A
rs3792109	21102463	677775	SCARNA5	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.12	2010	ATG16L1;SCARNA5	2	233275771	G	A
rs3792109	22936669	55054	ATG16L1	umls:C0010346	GWASCAT	A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300.	0.367863153	2013	ATG16L1;SCARNA5	2	233275771	G	A
rs3792876	17476680	6583	SLC22A4	umls:C0010346	GAD	[Polymorphisms 3020insC in CARD15 and SNP rs3792876 in SLC22A4/5 occurred statistically significantly more often in patients with pediatric-onset CD than in patients with adult-onset CD. Polymorphisms 3020insC in CARD15 and SNP rs2165047 in DLG5 were assoc]	0.079659542	2007	SLC22A4	5	132301616	C	T
rs3792876	17476680	6584	SLC22A5	umls:C0010346	GAD	[Polymorphisms 3020insC in CARD15 and SNP rs3792876 in SLC22A4/5 occurred statistically significantly more often in patients with pediatric-onset CD than in patients with adult-onset CD. Polymorphisms 3020insC in CARD15 and SNP rs2165047 in DLG5 were assoc]	0.079669474	2007	SLC22A4	5	132301616	C	T
rs3804099	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	TLR2	4	153703504	T	C
rs3804099	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR2	4	153703504	T	C
rs3804099	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	TLR2	4	153703504	T	C
rs3804099	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	TLR2	4	153703504	T	C
rs3804099	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	TLR2	4	153703504	T	C
rs3804099	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	TLR2	4	153703504	T	C
rs3804099	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	TLR2	4	153703504	T	C
rs3804099	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	TLR2	4	153703504	T	C
rs3804099	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	TLR2	4	153703504	T	C
rs3804099	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	TLR2	4	153703504	T	C
rs3804099	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR2	4	153703504	T	C
rs3804099	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	TLR2	4	153703504	T	C
rs3810936	21102463	9966	TNFSF15	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.164830311	2010	TNFSF15	9	114790605	T	C
rs3814055	21830270	8856	NR1I2	umls:C0010346	BeFree	Genomic DNA from 2823 individuals of Caucasian origin including 859 patients with Crohn's disease (CD), 464 patients with ulcerative colitis (UC), and 1500 healthy, unrelated controls was analyzed for eight PXR/NR1I2 single nucleotide polymorphisms (SNPs) (rs12721602 (-25564), rs3814055 (-25385), rs1523128 (-24756), rs1523127 (-24381), rs45610735 = p.Gly36Arg (+106), rs6785049 (+7635), rs2276707 (+8055), and rs3814057 (+11156)).	0.006991475	2011	NR1I2	3	119781188	C	T
rs3814057	21830270	8856	NR1I2	umls:C0010346	BeFree	Genomic DNA from 2823 individuals of Caucasian origin including 859 patients with Crohn's disease (CD), 464 patients with ulcerative colitis (UC), and 1500 healthy, unrelated controls was analyzed for eight PXR/NR1I2 single nucleotide polymorphisms (SNPs) (rs12721602 (-25564), rs3814055 (-25385), rs1523128 (-24756), rs1523127 (-24381), rs45610735 = p.Gly36Arg (+106), rs6785049 (+7635), rs2276707 (+8055), and rs3814057 (+11156)).	0.006991475	2011	NR1I2	3	119818407	A	C
rs3828309	18587394	55054	ATG16L1	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.367863153	2008	ATG16L1	2	233271764	A	G
rs386513644	20195480	56144	PCDHA4	umls:C0010346	BeFree	The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.	0.000271442	2010	NA	NA	NA	NA	NA
rs386525803	21830270	8856	NR1I2	umls:C0010346	BeFree	Genomic DNA from 2823 individuals of Caucasian origin including 859 patients with Crohn's disease (CD), 464 patients with ulcerative colitis (UC), and 1500 healthy, unrelated controls was analyzed for eight PXR/NR1I2 single nucleotide polymorphisms (SNPs) (rs12721602 (-25564), rs3814055 (-25385), rs1523128 (-24756), rs1523127 (-24381), rs45610735 = p.Gly36Arg (+106), rs6785049 (+7635), rs2276707 (+8055), and rs3814057 (+11156)).	0.006991475	2011	NA	NA	NA	NA	NA
rs386599677	23593463	7100	TLR5	umls:C0010346	BeFree	A non-synonymous coding variant (L616F) in the TLR5 gene is potentially associated with Crohn's disease and influences responses to bacterial flagellin.	0.003538676	2013	NA	NA	NA	NA	NA
rs3936503	19174780	219771	CCNY	umls:C0010346	GAD	[Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort.]	0.256926542	2009	CCNY	10	35260329	G	A
rs4077515	21102463	64170	CARD9	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.125005506	2010	CARD9	9	136372044	C	T
rs4077515	21102463	64170	CARD9	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.125005506	2010	CARD9	9	136372044	C	T
rs4149570	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TNFRSF1A	12	6342424	A	C
rs4149570	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	TNFRSF1A	12	6342424	A	C
rs4251961	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	IL1RN	2	113116890	T	C
rs4251961	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	IL1RN	2	113116890	T	C
rs4263839	21636646	9966	TNFSF15	umls:C0010346	BeFree	The Crohn's disease risk allele rs4263839 G in the TNFSF15 gene was significantly associated with an increased risk of both IBS (p=2.2×10(-5); OR 1.37) and more pronouncedly, IBS-C (p=8.7×10(-7); OR 1.79) in the entire sample.	0.164830311	2011	TNFSF15	9	114804160	A	G
rs4263839	18587394	9966	TNFSF15	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.164830311	2008	TNFSF15	9	114804160	A	G
rs4409764	25489960	22891	ZNF365	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.137383549	2015	NA	10	99524480	T	G
rs4409764	25489960	2859	GPR35	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.000271442	2015	NA	10	99524480	T	G
rs4409764	25489960	57178	ZMIZ1	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.125005506	2015	NA	10	99524480	T	G
rs4409764	25489960	29761	USP25	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.002638474	2015	NA	10	99524480	T	G
rs4409764	21102463	2805	GOT1	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.007372538	2010	NA	10	99524480	T	G
rs4409764	25489960	5771	PTPN2	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.269023212	2015	NA	10	99524480	T	G
rs4409764	25489960	159296	NKX2-3	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.274386036	2015	NA	10	99524480	T	G
rs4411591	24707144	7124	TNF	umls:C0010346	BeFree	Association of rs1568885, rs1813443 and rs4411591 polymorphisms with anti-TNF medication response in Greek patients with Crohn's disease.	0.422294957	2014	LINC01387	18	6550118	C	T
rs4537545	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	IL6R	1	154446403	C	T
rs4537545	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	IL6R	1	154446403	C	T
rs4537545	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	IL6R	1	154446403	C	T
rs45610735	21830270	8856	NR1I2	umls:C0010346	BeFree	Genomic DNA from 2823 individuals of Caucasian origin including 859 patients with Crohn's disease (CD), 464 patients with ulcerative colitis (UC), and 1500 healthy, unrelated controls was analyzed for eight PXR/NR1I2 single nucleotide polymorphisms (SNPs) (rs12721602 (-25564), rs3814055 (-25385), rs1523128 (-24756), rs1523127 (-24381), rs45610735 = p.Gly36Arg (+106), rs6785049 (+7635), rs2276707 (+8055), and rs3814057 (+11156)).	0.006991475	2011	NA	NA	NA	NA	NA
rs4613763	18587394	1601	DAB2	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.016569224	2008	NA	5	40392626	T	C
rs4613763	18587394	5734	PTGER4	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.018555193	2008	NA	5	40392626	T	C
rs4656940	21102463	51744	CD244	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.12	2010	CD244	1	160860478	A	G
rs4696480	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	TLR2	4	153685974	T	A
rs4696480	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	TLR2	4	153685974	T	A
rs4696480	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	TLR2	4	153685974	T	A
rs4696480	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	TLR2	4	153685974	T	A
rs4696480	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	TLR2	4	153685974	T	A
rs4696480	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR2	4	153685974	T	A
rs4696480	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR2	4	153685974	T	A
rs4696480	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	TLR2	4	153685974	T	A
rs4696480	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	TLR2	4	153685974	T	A
rs4696480	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	TLR2	4	153685974	T	A
rs4696480	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	TLR2	4	153685974	T	A
rs4696480	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	TLR2	4	153685974	T	A
rs4780355	22482804	8651	SOCS1	umls:C0010346	GWASCAT	In addition, we identified one susceptibility locus for CD (16p13 near SOCS1, p(rs4780355) = 4.99 × 10(-8)).	0.12	2012	SOCS1;LOC105371082	16	11254001	T	C
rs4802307	23128233	5536	PPP5C	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12	2012	PPP5C	19	46346549	G	T
rs4804803	18070336	30835	CD209	umls:C0010346	BeFree	A functional variant in the CD209 gene, rs4804803, does not seem to be influencing Crohn's disease susceptibility.	0.005362824	2007	CD209	19	7747847	A	G
rs4809330	21102463	84619	ZGPAT	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.127101096	2010	ZGPAT	20	63718234	A	G
rs4809330	21102463	84619	ZGPAT	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.127101096	2010	ZGPAT	20	63718234	A	G
rs4848306	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	NA	2	112840530	G	A
rs4848306	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	NA	2	112840530	G	A
rs4848306	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	NA	2	112840530	G	A
rs4848306	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	NA	2	112840530	G	A
rs4848306	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	NA	2	112840530	G	A
rs4848306	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	NA	2	112840530	G	A
rs4848306	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	NA	2	112840530	G	A
rs4848306	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	NA	2	112840530	G	A
rs4848306	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	NA	2	112840530	G	A
rs4848306	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	NA	2	112840530	G	A
rs4848306	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	NA	2	112840530	G	A
rs4848306	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	NA	2	112840530	G	A
rs4958847	19491842	55054	ATG16L1	umls:C0010346	BeFree	The aim of this study was to determine the role of the ATG16L1 (rs2241880) and IRGM (rs13361189 and rs4958847) genes polymorphism in Crohn's disease (CD) and ulcerative colitis (UC).	0.367863153	2009	IRGM	5	150860025	G	A
rs4958847	19491842	345611	IRGM	umls:C0010346	BeFree	The aim of this study was to determine the role of the ATG16L1 (rs2241880) and IRGM (rs13361189 and rs4958847) genes polymorphism in Crohn's disease (CD) and ulcerative colitis (UC).	0.17026908	2009	IRGM	5	150860025	G	A
rs4986790	18680223	64127	NOD2	umls:C0010346	BeFree	To evaluate the role of genetic factors in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC), we investigated the single nucleotide polymorphisms (SNPs) of NOD2/CARD15 (R702W, G908R and L1007finsC), and Toll-like receptor 4 (TLR4) genes (D299G and T399I) in a selected inflammatory bowel disease (IBD) population coming from Southern Italy.	0.56	2008	TLR4	9	117713024	A	G
rs4986790	20093834	7099	TLR4	umls:C0010346	BeFree	The Toll-like receptor 4 D299G and T399I polymorphisms are associated with Crohn's disease and ulcerative colitis: a meta-analysis.	0.182842621	2010	TLR4	9	117713024	A	G
rs4986790	17850411	7099	TLR4	umls:C0010346	BeFree	The TLR4 Asp299Gly and Thr399Ile polymorphisms were genotyped and tested for case-control frequency differences in a New Zealand white cohort of 389 Crohn's disease (CD) patients, 405 ulcerative colitis (UC) patients, and 416 population controls.	0.182842621	2007	TLR4	9	117713024	A	G
rs4986790	15973118	64127	NOD2	umls:C0010346	BeFree	The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease.	0.56	2005	TLR4	9	117713024	A	G
rs4986790	15973118	7099	TLR4	umls:C0010346	BeFree	The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease.	0.182842621	2005	TLR4	9	117713024	A	G
rs4986790	18174680	7099	TLR4	umls:C0010346	BeFree	In this two-center, retrospective German and Hungarian cohort study, patients with Crohn's disease (CD) (n = 379; German n = 235, Hungarian n = 144) and ulcerative colitis (UC) (n = 263; German n = 145, Hungarian n = 118) and healthy controls (n = 605; German n = 403, Hungarian n = 202) were genotyped for the presence of the CD14 c.1-260C>T promoter variant and the TLR4 c.896A>G (p.D299G) variant by melting curve analysis using fluorescence resonance energy transfer probes.	0.182842621	2007	TLR4	9	117713024	A	G
rs4986790	22918682	7099	TLR4	umls:C0010346	BeFree	Toll-like receptor (TLR) polymorphisms, and especially TLR-4 Asp299Gly and TLR-4 Thr399Ile, have been linked with Crohn's disease (CD) and to a lesser extent with ulcerative colitis (UC), CD behavior, and compromised seroreactivity to microbial antigens.	0.182842621	2013	TLR4	9	117713024	A	G
rs4986790	18493210	7099	TLR4	umls:C0010346	BeFree	To examine whether TLR4 Asp299Gly, CD14-260C/T, TNF-1031T/C, TNF-863C/A, TNF-857C/T, TACE-172C/T, and TACE-154C/A polymorphisms are associated with Crohn disease in the Ashkenazi Jewish population, we analyzed families with at least 1 child with Crohn disease for association with these mutations using a family-based association test (transmission disequilibrium test) for analysis.	0.182842621	2008	TLR4	9	117713024	A	G
rs4986790	18174680	929	CD14	umls:C0010346	BeFree	In this two-center, retrospective German and Hungarian cohort study, patients with Crohn's disease (CD) (n = 379; German n = 235, Hungarian n = 144) and ulcerative colitis (UC) (n = 263; German n = 145, Hungarian n = 118) and healthy controls (n = 605; German n = 403, Hungarian n = 202) were genotyped for the presence of the CD14 c.1-260C>T promoter variant and the TLR4 c.896A>G (p.D299G) variant by melting curve analysis using fluorescence resonance energy transfer probes.	0.031095058	2007	TLR4	9	117713024	A	G
rs4986790	18493210	6868	ADAM17	umls:C0010346	BeFree	To examine whether TLR4 Asp299Gly, CD14-260C/T, TNF-1031T/C, TNF-863C/A, TNF-857C/T, TACE-172C/T, and TACE-154C/A polymorphisms are associated with Crohn disease in the Ashkenazi Jewish population, we analyzed families with at least 1 child with Crohn disease for association with these mutations using a family-based association test (transmission disequilibrium test) for analysis.	0.002909916	2008	TLR4	9	117713024	A	G
rs4986790	18174680	4695	NDUFA2	umls:C0010346	BeFree	In this two-center, retrospective German and Hungarian cohort study, patients with Crohn's disease (CD) (n = 379; German n = 235, Hungarian n = 144) and ulcerative colitis (UC) (n = 263; German n = 145, Hungarian n = 118) and healthy controls (n = 605; German n = 403, Hungarian n = 202) were genotyped for the presence of the CD14 c.1-260C>T promoter variant and the TLR4 c.896A>G (p.D299G) variant by melting curve analysis using fluorescence resonance energy transfer probes.	0.004614512	2007	TLR4	9	117713024	A	G
rs4986790	18213697	7099	TLR4	umls:C0010346	BeFree	Novel NOD2 haplotype strengthens the association between TLR4 Asp299gly and Crohn's disease in an Australian population.	0.182842621	2008	TLR4	9	117713024	A	G
rs4986790	18680223	7099	TLR4	umls:C0010346	BeFree	To evaluate the role of genetic factors in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC), we investigated the single nucleotide polymorphisms (SNPs) of NOD2/CARD15 (R702W, G908R and L1007finsC), and Toll-like receptor 4 (TLR4) genes (D299G and T399I) in a selected inflammatory bowel disease (IBD) population coming from Southern Italy.	0.182842621	2008	TLR4	9	117713024	A	G
rs4986790	18213697	64127	NOD2	umls:C0010346	BeFree	Novel NOD2 haplotype strengthens the association between TLR4 Asp299gly and Crohn's disease in an Australian population.	0.56	2008	TLR4	9	117713024	A	G
rs4986791	15973118	7099	TLR4	umls:C0010346	BeFree	The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease.	0.182842621	2005	TLR4	9	117713324	C	T
rs4986791	22918682	7099	TLR4	umls:C0010346	BeFree	Toll-like receptor (TLR) polymorphisms, and especially TLR-4 Asp299Gly and TLR-4 Thr399Ile, have been linked with Crohn's disease (CD) and to a lesser extent with ulcerative colitis (UC), CD behavior, and compromised seroreactivity to microbial antigens.	0.182842621	2013	TLR4	9	117713324	C	T
rs4986791	17850411	7099	TLR4	umls:C0010346	BeFree	The TLR4 Asp299Gly and Thr399Ile polymorphisms were genotyped and tested for case-control frequency differences in a New Zealand white cohort of 389 Crohn's disease (CD) patients, 405 ulcerative colitis (UC) patients, and 416 population controls.	0.182842621	2007	TLR4	9	117713324	C	T
rs4986791	15973118	64127	NOD2	umls:C0010346	BeFree	The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease.	0.56	2005	TLR4	9	117713324	C	T
rs4986791	18680223	7099	TLR4	umls:C0010346	BeFree	To evaluate the role of genetic factors in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC), we investigated the single nucleotide polymorphisms (SNPs) of NOD2/CARD15 (R702W, G908R and L1007finsC), and Toll-like receptor 4 (TLR4) genes (D299G and T399I) in a selected inflammatory bowel disease (IBD) population coming from Southern Italy.	0.182842621	2008	TLR4	9	117713324	C	T
rs4986791	18680223	64127	NOD2	umls:C0010346	BeFree	To evaluate the role of genetic factors in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC), we investigated the single nucleotide polymorphisms (SNPs) of NOD2/CARD15 (R702W, G908R and L1007finsC), and Toll-like receptor 4 (TLR4) genes (D299G and T399I) in a selected inflammatory bowel disease (IBD) population coming from Southern Italy.	0.56	2008	TLR4	9	117713324	C	T
rs4986791	20093834	7099	TLR4	umls:C0010346	BeFree	The Toll-like receptor 4 D299G and T399I polymorphisms are associated with Crohn's disease and ulcerative colitis: a meta-analysis.	0.182842621	2010	TLR4	9	117713324	C	T
rs5030728	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR4	9	117712004	G	A
rs5030728	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	TLR4	9	117712004	G	A
rs5030728	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	TLR4	9	117712004	G	A
rs5030728	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	TLR4	9	117712004	G	A
rs5030728	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	TLR4	9	117712004	G	A
rs5030728	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	TLR4	9	117712004	G	A
rs5030728	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	TLR4	9	117712004	G	A
rs5030728	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	TLR4	9	117712004	G	A
rs5030728	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	TLR4	9	117712004	G	A
rs5030728	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	TLR4	9	117712004	G	A
rs5030728	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	TLR4	9	117712004	G	A
rs5030728	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	TLR4	9	117712004	G	A
rs504963	20570966	2524	FUT2	umls:C0010346	GWASCAT	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	0.247177041	2010	FUT2;LOC105447645	19	48705608	G	A
rs514000	25489960	5771	PTPN2	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.269023212	2015	PTPN2	18	12854073	C	T
rs514000	25489960	2859	GPR35	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.000271442	2015	PTPN2	18	12854073	C	T
rs514000	25489960	57178	ZMIZ1	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.125005506	2015	PTPN2	18	12854073	C	T
rs514000	25489960	22891	ZNF365	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.137383549	2015	PTPN2	18	12854073	C	T
rs514000	25489960	29761	USP25	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.002638474	2015	PTPN2	18	12854073	C	T
rs514000	25489960	159296	NKX2-3	umls:C0010346	BeFree	We confirmed 6 previously reported loci in Caucasian: GPR35 at 2q37 (rs3749172; P = 5.30 × 10, odds ratio [OR] = 1.45), ZNF365 at 10q21 (rs224143; P = 2.20 × 10, OR = 1.38), ZMIZ1 at 10q22 (rs1250569; P = 3.05 × 10, OR = 1.30), NKX2-3 at 10q24 (rs4409764; P = 7.93 × 10, OR = 1.32), PTPN2 at 18p11 (rs514000; P = 9.00 × 10, OR = 1.33), and USP25 at 21q11 (rs2823256; P = 2.49 × 10, OR = 1.35), bringing the number of known CD loci (including 3 in the HLA) in Koreans to 15.	0.274386036	2015	PTPN2	18	12854073	C	T
rs516246	23128233	2524	FUT2	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.247177041	2012	FUT2;LOC105447645	19	48702915	C	T
rs5743289	17447842	64127	NOD2	umls:C0010346	GWASCAT	Two of these (IL23R on Chromosome 1 and CARD15 on Chromosome 16) correspond to genes previously reported to be associated with CD.	0.56	2007	NOD2	16	50722863	C	G,T
rs5743289	17804789	64127	NOD2	umls:C0010346	GWASCAT	A proportion of these were replicated in two independent German Caucasian samples, including the established CD loci NOD2 and IBD5.	0.56	2007	NOD2	16	50722863	C	G,T
rs5743293	19570052	64127	NOD2	umls:C0010346	BeFree	NOD2/CARD15 is involved in the innate immune response and three polymorphisms in this gene (Arg702Trp rs2066844, Gly908Arg rs2066845 and Leu1007fsinsC rs5743293) have been associated with risk of the rare Crohn's disease.	0.56	2010	NOD2	16	50729870	-	C
rs5744174	23593463	7100	TLR5	umls:C0010346	BeFree	A non-synonymous coding variant (L616F) in the TLR5 gene is potentially associated with Crohn's disease and influences responses to bacterial flagellin.	0.003538676	2013	TLR5	1	223111186	A	G
rs60872763	21251066	1493	CTLA4	umls:C0010346	BeFree	Association of cytotoxic T lymphocyte associated antigen-4 gene (rs60872763) polymorphism with Crohn's disease and high levels of serum sCTLA-4 in Crohn's disease.	0.014635455	2011	CTLA4	2	203873378	ATATAT	-
rs6478106	23266558	3133	HLA-E	umls:C0010346	BeFree	We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)).	0.001628651	2013	NA	9	114783386	C	T
rs6478106	23266558	9966	TNFSF15	umls:C0010346	BeFree	We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)).	0.164830311	2013	NA	9	114783386	C	T
rs6478106	23266558	6774	STAT3	umls:C0010346	BeFree	We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)).	0.146189242	2013	NA	9	114783386	C	T
rs6545946	22412388	200728	TMEM17	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.12	2012	TMEM17	2	62486398	C	T
rs6545946	22412388	10678	B3GNT2	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.002367032	2012	TMEM17	2	62486398	C	T
rs6556412	21102463	285626	LOC285626	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.12	2010	LOC285626	5	159360377	G	A
rs6601764	17554300	1316	KLF6	umls:C0010346	GAD	[Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.]	0.002367032	2007	NA	10	3820350	C	T
rs6679677	23128233	10745	PHTF1	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12	2012	PHTF1	1	113761186	C	A
rs6716753	23128233	11262	SP140	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.122367032	2012	SP140	2	230232414	T	C
rs6738825	21102463	5334	PLCL1	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.002367032	2010	PLCL1	2	198032171	A	G
rs6785049	21830270	8856	NR1I2	umls:C0010346	BeFree	Genomic DNA from 2823 individuals of Caucasian origin including 859 patients with Crohn's disease (CD), 464 patients with ulcerative colitis (UC), and 1500 healthy, unrelated controls was analyzed for eight PXR/NR1I2 single nucleotide polymorphisms (SNPs) (rs12721602 (-25564), rs3814055 (-25385), rs1523128 (-24756), rs1523127 (-24381), rs45610735 = p.Gly36Arg (+106), rs6785049 (+7635), rs2276707 (+8055), and rs3814057 (+11156)).	0.006991475	2011	NR1I2	3	119814886	G	A
rs6837335	23128233	57606	SLAIN2	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12	2012	SLAIN2	4	48361966	A	G
rs6887695	25761185	3593	IL12B	umls:C0010346	BeFree	Our genetic association study revealed that the polymorphisms of IL12B rs6887695 were associated with both CD and ulcerative colitis (UC) susceptibility in Chinese population, but did not affect the serum IL12p40 level in either CD patients or UC patients.	0.144832032	2015	NA	5	159395637	G	C
rs6887695	17554261	3593	IL12B	umls:C0010346	GAD	[Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.]	0.144832032	2007	NA	5	159395637	G	C
rs6908425	18587394	54901	CDKAL1	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.136569224	2008	CDKAL1	6	20728500	T	C
rs6908425	21102463	54901	CDKAL1	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.136569224	2010	CDKAL1	6	20728500	T	C
rs6908425	18587394	54901	CDKAL1	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.136569224	2008	CDKAL1	6	20728500	T	C
rs6927172	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	NA	6	137681038	C	G
rs6927172	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	NA	6	137681038	C	G
rs6927172	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	NA	6	137681038	C	G
rs6927172	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	NA	6	137681038	C	G
rs6927172	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	NA	6	137681038	C	G
rs6927172	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	NA	6	137681038	C	G
rs6927172	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	NA	6	137681038	C	G
rs6927172	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	NA	6	137681038	C	G
rs6927172	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	NA	6	137681038	C	G
rs6927172	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	NA	6	137681038	C	G
rs6927172	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	NA	6	137681038	C	G
rs6927172	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	NA	6	137681038	C	G
rs694739	21102463	25824	PRDX5	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.002367032	2010	LOC102723878	11	64329761	A	G
rs694739	21102463	102723878	LOC102723878	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.12	2010	LOC102723878	11	64329761	A	G
rs696	24971461	7097	TLR2	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.008729747	2014	NFKBIA	14	35401887	C	T
rs696	24971461	7099	TLR4	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.182842621	2014	NFKBIA	14	35401887	C	T
rs696	24971461	5468	PPARG	umls:C0010346	BeFree	The polymorphisms TLR2 (rs1816702), NFKB1 (rs28362491), TNFRSF1A (rs4149570), IL6R (rs4537545), IL23R (rs11209026) and PTPN22 (rs2476601) were associated with risk of CD and the polymorphisms TLR2 (rs1816702), TLR4 (rs1554973 and rs12377632), TLR9 (rs352139), LY96 (rs11465996), NFKBIA (rs696), TNFA (rs1800629), TNFRSF1A (rs4149570), IL10 (rs3024505), IL23R (rs11209026), PTPN22 (rs2476601) and PPARG (rs1801282) were associated with risk of UC.	0.126091273	2014	NFKBIA	14	35401887	C	T
rs7076156	22412388	22891	ZNF365	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.137383549	2012	ZNF365;LOC105378327	10	62655424	A	G
rs7076156	22412388	22891	ZNF365	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.137383549	2012	ZNF365;LOC105378327	10	62655424	A	G
rs7222094	24776844	54106	TLR9	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130825337	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	7124	TNF	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.422294957	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	4790	NFKB1	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008262808	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	7099	TLR4	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.182842621	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	23643	LY96	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	9020	MAP3K14	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.000271442	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	3458	IFNG	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.130334654	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	7132	TNFRSF1A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.09801231	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	4695	NDUFA2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004614512	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	7097	TLR2	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.008729747	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	7128	TNFAIP3	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.003181358	2014	MAP3K14	17	45290287	T	C
rs7222094	24776844	3605	IL17A	umls:C0010346	BeFree	Nineteen functional polymorphisms that alter the NFκB-mediated inflammatory response (TLR2 (rs3804099, rs11938228, rs1816702, rs4696480), TLR4 (rs5030728, rs1554973), TLR9 (rs187084, rs352139), LY96 (MD-2) (rs11465996), CD14 (rs2569190), MAP3K14 (NIK) (rs7222094)), TNF-α signaling (TNFA (TNF-α) (rs361525), TNFRSF1A (TNFR1) (rs4149570), TNFAIP3(A20) (rs6927172)) and other cytokines regulated by NFκB (IL1B (rs4848306), IL1RN (rs4251961), IL6 (rs10499563), IL17A (rs2275913), IFNG (rs2430561)) were associated with response to anti-TNF therapy among patients with CD, UC or both CD and UC (P ⩽ 0.05).	0.004071628	2014	MAP3K14	17	45290287	T	C
rs7282490	24837102	64127	NOD2	umls:C0010346	BeFree	MDDC from rs7282490 GG risk-carriers had reduced ICOSL expression and PRR-initiated signaling and this loss-of-function ICOSLG risk allele associated with an ileal Crohn's disease phenotype, similar to polymorphisms in NOD2.	0.56	2014	LOC105377139	21	44195858	G	A
rs72981516	23266558	9873	FCHSD2	umls:C0010346	GWASCAT	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	0.12	2013	FCHSD2	11	72959855	T	G
rs7329174	23266558	1997	ELF1	umls:C0010346	GWASCAT	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	0.12	2013	ELF1	13	40983974	A	G
rs736289	21102463	56301	SLC7A10	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.002367032	2010	NA	19	33266156	T	C
rs740495	21102463	22904	SBNO2	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.124734064	2010	SBNO2	19	1124836	A	G
rs7423615	21102463	11262	SP140	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.122367032	2010	SP140	2	230252159	C	T
rs7423615	21102463	11262	SP140	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.122367032	2010	SP140	2	230252159	C	T
rs744166	18587394	6774	STAT3	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.146189242	2008	STAT3	17	42362183	A	G
rs744166	25286337	6774	STAT3	umls:C0010346	BeFree	Associations between STAT3 rs744166 polymorphisms and susceptibility to ulcerative colitis and Crohn's disease: a meta-analysis.	0.146189242	2014	STAT3	17	42362183	A	G
rs744166	18587394	6774	STAT3	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.146189242	2008	STAT3	17	42362183	A	G
rs74825699	21245992	8856	NR1I2	umls:C0010346	BeFree	Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.	0.006991475	2011	NR1I2	3	119783118	G	A
rs74825699	21245992	4790	NFKB1	umls:C0010346	BeFree	Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs 6785049); and liver X receptor (LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients, 495 ulcerative colitis (UC) patients, and 779 healthy controls.	0.008262808	2011	NR1I2	3	119783118	G	A
rs751728	23850713	4295	MLN	umls:C0010346	GWASCAT	Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.	0.120542884	2014	MLN;LOC105375024	6	33796256	C	T
rs7517847	17435756	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.	0.370597435	2007	IL23R	1	67215986	T	G
rs7517847	18383521	149233	IL23R	umls:C0010346	BeFree	The data show an association of both IL23R SNPs with overall IBD (statistically stronger, rs7517847; odds ratio [OR] = 0.79, 95% confidence interval [CI]: 0.67-0.94, minor allele frequencies: 0.355 in IBD patients versus 0.410 in controls; P = 0.005), somewhat stronger in Crohn's disease (OR = 0.74, 95% CI: 0.61-0.91) than in ulcerative colitis (OR = 0.84, 95% CI: 0.69-1.03).	0.370597435	2008	IL23R	1	67215986	T	G
rs7530511	25159710	149233	IL23R	umls:C0010346	BeFree	We found that IL23R (L310P) variant conferred a protective effect for crohn's disease (CD) but not ulcerative colitis (UC) patients.	0.370597435	2014	IL23R	1	67219704	T	C
rs7554511	21102463	55765	C1orf106	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.120271442	2010	C1orf106	1	200908434	C	A
rs7574865	18759272	6775	STAT4	umls:C0010346	BeFree	The association of STAT4 polymorphism rs7574865 with RA was validated in patients of Spanish origin (for T versus G, P = 1.2 x 10(-6), odds ratio [OR] 1.59, 95% confidence interval [95% CI] 1.31-1.92), and the association was described for the first time in both clinical forms of inflammatory bowel disease, Crohn's disease and ulcerative colitis (for T versus G, P = 0.006, OR 1.29, 95% CI 1.07-1.55), and in type 1 diabetes mellitus (for T versus G, P = 0.008, OR 1.36, 95% CI 1.07-1.71).	0.005819831	2008	STAT4	2	191099907	T	G
rs7574865	20454450	6775	STAT4	umls:C0010346	BeFree	Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.	0.005819831	2010	STAT4	2	191099907	T	G
rs762421	18587394	23308	ICOSLG	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.00764398	2008	LOC105377139	21	44195678	G	A
rs762421	18587394	8209	C21orf33	umls:C0010346	GWASCAT	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	0.122367032	2008	LOC105377139	21	44195678	G	A
rs762421	18587394	8209	C21orf33	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.122367032	2008	LOC105377139	21	44195678	G	A
rs763780	18088064	112744	IL17F	umls:C0010346	BeFree	Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD.	0.002909916	2008	IL17F;LOC105375088	6	52236941	T	C
rs763780	18088064	149233	IL23R	umls:C0010346	BeFree	Given the association of IL23R with inflammatory bowel disease (IBD), we characterized the role of IL-17F in IBD including its intestinal gene expression and the effect of the IL17F p.His161Arg polymorphism on disease susceptibility and phenotype of Crohn's disease (CD) and ulcerative colitis (UC).	0.370597435	2008	IL17F;LOC105375088	6	52236941	T	C
rs76418789	21672939	3605	IL17A	umls:C0010346	BeFree	A case-control analysis showed that development of Crohn's disease is associated with the IL-23R variant G149R (OR 0.32, 95% CI 0.15 to 0.68) and IL-17A variant IVS1+18G>C (OR 10.65, 95% CI 1.32 to 85.89).	0.004071628	2011	IL23R	1	67182913	G	A
rs76418789	21672939	149233	IL23R	umls:C0010346	BeFree	A case-control analysis showed that development of Crohn's disease is associated with the IL-23R variant G149R (OR 0.32, 95% CI 0.15 to 0.68) and IL-17A variant IVS1+18G>C (OR 10.65, 95% CI 1.32 to 85.89).	0.370597435	2011	IL23R	1	67182913	G	A
rs76418789	23850713	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.	0.370597435	2014	IL23R	1	67182913	G	A
rs7702331	21102463	134288	TMEM174	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.002367032	2010	LOC105379031	5	73255307	A	G
rs7705924	22412388	100861468	LINC00492	umls:C0010346	GWASCAT	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	0.12	2012	LINC00491;LINC00492	5	102611094	A	G
rs7705924	22412388	133482	SLCO6A1	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.002367032	2012	LINC00491;LINC00492	5	102611094	A	G
rs7765379	23266558	9966	TNFSF15	umls:C0010346	BeFree	We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)).	0.164830311	2013	NA	6	32713151	T	G
rs7765379	23266558	6774	STAT3	umls:C0010346	BeFree	We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)).	0.146189242	2013	NA	6	32713151	T	G
rs7765379	23266558	3133	HLA-E	umls:C0010346	BeFree	We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)).	0.001628651	2013	NA	6	32713151	T	G
rs780093	21102463	2646	GCKR	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.127101096	2010	GCKR	2	27519736	T	C
rs780093	21102463	2646	GCKR	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.127101096	2010	GCKR	2	27519736	T	C
rs7807268	17554300	26047	CNTNAP2	umls:C0010346	GAD	[Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.]	0.002367032	2007	LOC105375557	7	148560956	G	C
rs7927894	18587394	56946	C11orf30	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.004734064	2008	NA	11	76590272	C	T
rs8005161	21102463	8477	GPR65	umls:C0010346	GWASCAT	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	0.122367032	2010	GPR65	14	88006251	C	T
rs8005161	21102463	8477	GPR65	umls:C0010346	GAD	[Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.]	0.122367032	2010	GPR65	14	88006251	C	T
rs864745	23128233	221895	JAZF1	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12	2012	JAZF1	7	28140937	T	C
rs888208	21514341	159296	NKX2-3	umls:C0010346	BeFree	A total of 344 patients with Crohn's disease (CD), 253 patients with ulcerative colitis (UC), and 243 healthy controls (HCs) were genotyped for 3 tag-single nucleotide polymorphisms (SNPs; rs10883365, rs888208, and rs11596008) around NKX2.3.	0.274386036	2011	NKX2-3	10	99536106	A	G
rs9286879	18587394	356	FASLG	umls:C0010346	GAD	[Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.]	0.012378044	2008	NA	1	172893094	A	G
rs9292777	22412388	1601	DAB2	umls:C0010346	GAD	[A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.]	0.016569224	2012	NA	5	40437846	C	T
rs9292777	17554261	1601	DAB2	umls:C0010346	GAD	[Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.]	0.016569224	2007	NA	5	40437846	C	T
rs9469220	17554300	3119	HLA-DQB1	umls:C0010346	GAD	[Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.]	0.005005506	2007	NA	6	32690533	G	A
rs9491697	23128233	84870	RSPO3	umls:C0010346	GWASCAT	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	0.12	2012	RSPO3;LOC105377988	6	127134977	A	G
rs9858542	17554300	4485	MST1	umls:C0010346	GAD	[Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.]	0.255830843	2007	BSN	3	49664550	G	A
rs9858542	17554300	8927	BSN	umls:C0010346	GWASCAT	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	0.134473634	2007	BSN	3	49664550	G	A
rs9858542	17554261	8927	BSN	umls:C0010346	GAD	[Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.]	0.134473634	2007	BSN	3	49664550	G	A
rs9858542	17554300	8927	BSN	umls:C0010346	GAD	[Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.]	0.134473634	2007	BSN	3	49664550	G	A
rs9858542	17554261	8927	BSN	umls:C0010346	GWASCAT	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	0.134473634	2007	BSN	3	49664550	G	A
rs9858542	17554261	4485	MST1	umls:C0010346	GAD	[Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.]	0.255830843	2007	BSN	3	49664550	G	A
rs9891119	23266558	6774	STAT3	umls:C0010346	GWASCAT	We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)).	0.146189242	2013	STAT3	17	42355962	A	C
rs9891119	23266558	6774	STAT3	umls:C0010346	BeFree	We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)).	0.146189242	2013	STAT3	17	42355962	A	C
rs9891119	23266558	9966	TNFSF15	umls:C0010346	BeFree	We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)).	0.164830311	2013	STAT3	17	42355962	A	C
rs9891119	23266558	3133	HLA-E	umls:C0010346	BeFree	We confirmed associations of Crohn's disease with variants in MHC (rs7765379, P = 2.11 × 10(-59)), TNFSF15 (rs6478106, P = 3.87 × 10(-45)), and STAT3 (rs9891119, P = 2.24 × 10(-14)).	0.001628651	2013	STAT3	17	42355962	A	C
rs9988642	17804789	149233	IL23R	umls:C0010346	GWASCAT	Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.	0.370597435	2007	IL23R	1	67260421	T	C

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:1143)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	6672729	rs11583755	A	C	rs11583755	23665963	2.30E-05	NA	1.67	NA	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	7832212	rs707458	C	T	rs707458	18587394	6.82E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
1	7879063	rs2797685	C	T	rs2797685	21102463	7.00E-09	NA	1.05	[1.01-1.10]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2797685-A	Research Support, N.I.H., Extramural	Meta-Analysis
1	7906008	rs707472	G	T	rs707472	18587394	3.63E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
1	15440156	rs6659639	G	A	rs6659639	17684544	5.17E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	19718824	rs7667	G	A	rs7667	22482804	8.00E-06	NA	1.11	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
1	23160272	rs4654821	T	A,C,G	rs4654821	20570966	4.40E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	25273200	rs7551188	T	C	rs7551188	23266558	9.00E-06	NA	1.18	[1.10-1.28]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7551188-T	Research Support, Non-U.S. Gov't	Comparative Study
1	39164153	rs10493084	G	A	rs10493084	17684544	1.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	49463801	rs3118223	G	A	rs3118223	17684544	8.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	64231541	rs2819130	G	A	rs2819130	17435756	2.10E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
1	64277035	rs596985	A	G	rs596985	23850713	4.13E-05	NA	1.31	[1.15-1.48]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs596985-A	Research Support, Non-U.S. Gov't	Validation Studies
1	67370292	rs1925411	C	T	rs1925411	17804789	4.20E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67372061	rs1983860	G	T	rs1983860	17804789	3.58E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67449941	rs4620509	A	G	rs4620509	17804789	6.13E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
1	67460791	rs4486425	T	C	rs4486425	17804789	5.47E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67510857	rs2815380	G	A	rs2815380	17804789	8.04E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
1	67512695	rs1024228	A	G	rs1024228	17804789	1.23E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67513574	rs2208577	A	C	rs2208577	17804789	8.91E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
1	67517022	rs2755259	T	C	rs2755259	17804789	1.87E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67521736	rs2755262	T	C	rs2755262	17804789	2.01E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67525043	rs11208994	A	G	rs11208994	17804789	1.51E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67529243	rs2755263	A	G	rs2755263	17804789	5.13E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
1	67579395	rs17129659	C	T	rs17129659	17804789	8.32E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67590461	rs11209002	T	C	rs11209002	17804789	2.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67599657	rs4655679	C	T	rs4655679	17804789	2.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67601132	rs11209003	G	T	rs11209003	17804789	1.00E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67607082	rs9729046	C	G	rs9729046	17804789	5.87E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67611613	rs4655683	G	A	rs4655683	17068223	2.95E-04	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	A
1	67611613	rs4655683	G	A	rs4655683	17804789	4.76E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
1	67615487	rs10889657	T	C	rs10889657	17804789	2.31E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67623298	rs11209008	G	A	rs11209008	17804789	8.79E-09	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67625309	rs10889661	T	A	rs10889661	17804789	3.56E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67635475	rs10889664	C	T	rs10889664	17804789	4.15E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67648596	rs76418789	G	A	rs76418789	23850713	2.00E-10	NA	2.06	[1.64-2.58]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs76418789-G	Research Support, Non-U.S. Gov't	Validation Studies
1	67653010	rs2064689	G	A	rs2064689	17068223	8.52E-05	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	G
1	67653010	rs2064689	G	A	rs2064689	17804789	1.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67655147	rs17375018	G	A	rs17375018	17804789	8.71E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67656931	rs12401432	C	G	rs12401432	17804789	6.44E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67662622	rs10489630	A	C	rs10489630	17068223	7.07E-05	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	T
1	67662622	rs10489630	A	C	rs10489630	17804789	1.26E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67664154	rs714512	T	G	rs714512	17804789	1.60E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67665543	rs7556198	A	G	rs7556198	17804789	1.48E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67670133	rs1004820	T	G	rs1004820	17804789	4.58E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
1	67670213	rs1004819	G	A	rs1004819	17068223	1.78E-14	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	C
1	67670213	rs1004819	G	A	rs1004819	17804789	6.25E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67670916	rs2902440	G	A	rs2902440	17804789	8.81E-09	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67672765	rs7539625	G	A	rs7539625	17804789	2.15E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67675516	rs11805303	C	T	rs11805303	17554300	6.00E-12	NA	1.39	[1.22-1.58]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11805303-T	Multicenter Study	Research Support, N.I.H., Extramural
1	67675516	rs11805303	C	T	rs11805303	18587394	1.82E-39	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
1	67675728	rs10889669	T	G	rs10889669	17804789	6.53E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67679990	rs2019262	G	A	rs2019262	17804789	9.20E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67681669	rs7517847	T	G	rs7517847	17435756	3.00E-12	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
1	67681669	rs7517847	T	G	rs7517847	17804789	7.80E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67685443	rs7518660	G	A	rs7518660	17804789	6.18E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67685598	rs11465802	A	C	rs11465802	17804789	5.04E-07	NA	2.56	[1.75-3.70]	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
1	67687064	rs10789228	C	T	rs10789228	17804789	1.00E-04	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67688349	rs10489629	T	C	rs10489629	17068223	1.62E-11	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	G
1	67694202	rs2201841	A	G	rs2201841	17068223	1.10E-14	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	T
1	67694202	rs2201841	A	G	rs2201841	17804789	3.16E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67696547	rs12031203	G	A	rs12031203	17804789	1.33E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67699254	rs11804284	T	C	rs11804284	17804789	2.64E-17	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67701765	rs12030948	G	T	rs12030948	17068223	3.33E-05	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	G
1	67702526	rs11465804	T	G	rs11465804	17068223	3.33E-16	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	T
1	67702526	rs11465804	T	G	rs11465804	17447842	3.50E-15	NA	NA	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67702526	rs11465804	T	G	rs11465804	17804789	2.08E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67702526	rs11465804	T	G	rs11465804	18587394	7.00E-63	NA	2.5	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11465804-T	Research Support, N.I.H., Extramural	Meta-Analysis
1	67702526	rs11465804	T	G	rs11465804	20570966	1.00E-06	NA	1.89	[1.47-2.44]	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	67704107	rs10489628	G	A	rs10489628	17068223	1.96E-04	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	T
1	67705958	rs11209026	G	A	rs11209026	17447842	2.00E-18	NA	2.92	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67705958	rs11209026	G	A	rs11209026	17684544	2.17E-07	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67705958	rs11209026	G	A	rs11209026	17804789	1.32E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67705958	rs11209026	G	A	rs11209026	18587394	2.15E-68	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
1	67705958	rs11209026	G	A	rs11209026	21102463	1.00E-64	NA	2.66	[2.36-3.00]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11209026-G	Research Support, N.I.H., Extramural	Meta-Analysis
1	67705958	rs11209026	G	A	rs11209026	22293688	4.00E-21	NA	3.18	[2.91-3.44]	16,179 European ancestry individuals	European(16179)	ALL(16179)	EUR(16179)	ALL(16179)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	67705958	rs11209026	G	A	rs11209026	22412388	1.00E-18	NA	2.2	[2.10-2.35]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11209026-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	67705958	rs11209026	G	A	rs11209026	22936669	4.00E-14	NA	2.84	NA	1,277 European ancestry cases; 1,488 European ancestry controls	European(2765)	ALL(2765)	EUR(2765)	ALL(2765)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11209026-G	Research Support, Non-U.S. Gov't	G
1	67708670	rs6682033	A	G	rs6682033	17068223	4.10E-04	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	A
1	67719129	rs1343151	G	A	rs1343151	17068223	2.74E-12	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	T
1	67719129	rs1343151	G	A	rs1343151	17447842	2.30E-09	NA	NA	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67719129	rs1343151	G	A	rs1343151	17804789	3.16E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67722567	rs10889676	C	A	rs10889676	17804789	3.36E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67725120	rs10889677	C	A	rs10889677	17068223	3.40E-14	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	C
1	67725120	rs10889677	C	A	rs10889677	17447842	2.40E-06	NA	NA	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67725120	rs10889677	C	A	rs10889677	17804789	2.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67726104	rs9988642	T	C	rs9988642	17804789	3.16E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67728018	rs12567232	G	A	rs12567232	17804789	2.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67730055	rs6669582	A	G	rs6669582	17804789	1.38E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
1	67730628	rs10789230	G	T	rs10789230	17804789	2.37E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67731368	rs7547569	T	C	rs7547569	17804789	2.99E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67732603	rs7539328	G	A	rs7539328	17068223	8.44E-07	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	G
1	67735948	rs11583760	C	T	rs11583760	17804789	3.95E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67740092	rs11209032	G	A	rs11209032	17068223	5.50E-13	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	G
1	67744500	rs11209033	C	G	rs11209033	17804789	1.44E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	67747415	rs12119179	A	C	rs12119179	17804789	8.36E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
1	67750474	rs7546245	T	C	rs7546245	17804789	4.71E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	67752671	rs11209040	G	A,C	rs11209040	17804789	8.43E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	67753508	rs1495965	C	T	rs1495965	17068223	3.55E-09	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	G
1	67760140	rs924080	T	C	rs924080	17068223	3.83E-06	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	T
1	78623626	rs17391694	C	T	rs17391694	23128233	3.00E-09	NA	1.13	[1.08-1.19]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs17391694-C	Research Support, N.I.H., Extramural	Meta-Analysis
1	82210952	rs1391475	T	C	rs1391475	20570966	1.70E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	98928937	rs770918	A	G	rs770918	17684544	9.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	99458974	rs10489924	T	C	rs10489924	17684544	7.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	111823220	rs4323713	G	T	rs4323713	17684544	4.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	114303808	rs6679677	C	A	rs6679677	18587394	4.95E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
1	114303808	rs6679677	C	A	rs6679677	23128233	2.00E-15	NA	1.2	[1.13-1.27]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6679677-C	Research Support, N.I.H., Extramural	Meta-Analysis
1	114377568	rs2476601	A	G	rs2476601	18587394	1.00E-08	NA	1.31	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2476601-G	Research Support, N.I.H., Extramural	Meta-Analysis
1	114377568	rs2476601	A	G	rs2476601	21102463	4.00E-09	NA	1.26	[1.17-1.37]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2476601-G	Research Support, N.I.H., Extramural	Meta-Analysis
1	120451190	rs3897478	T	C	rs3897478	23128233	2.00E-11	NA	1.16	[1.10-1.22]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3897478-T	Research Support, N.I.H., Extramural	Meta-Analysis
1	147023894	rs10494251	C	T	rs10494251	17684544	9.83E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	147108260	rs10494248	G	A	rs10494248	17684544	7.90E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	147254256	rs1342705	C	T	rs1342705	17684544	2.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	147254569	rs10494257	T	C	rs10494257	17684544	5.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
1	155230131	rs1142287	C	T	rs1142287	21102463	2.00E-13	NA	NA	NA	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
1	155230131	rs1142287	C	T	rs3180018	21102463	2.00E-13	NA	1.13	[1.06-1.19]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3180018-A	Research Support, N.I.H., Extramural	Meta-Analysis
1	155282829	rs11264359	A	G	rs11264359	20570966	3.80E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	155478897	rs6688636	T	C	rs6688636	20570966	4.30E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	160830268	rs4656940	A	G	rs4656940	21102463	6.00E-07	NA	1.15	[1.09-1.21]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4656940-A	Research Support, N.I.H., Extramural	Meta-Analysis
1	160852046	rs2274910	T	C	rs2274910	18587394	1.00E-09	NA	1.14	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2274910-C	Research Support, N.I.H., Extramural	Meta-Analysis
1	160878913	rs11265519	C	A	rs11265519	18587394	3.82E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
1	162930820	rs2343331	C	T	rs2343331	17435756	2.49E-05	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
1	172853460	rs7517810	C	T	rs7517810	21102463	2.00E-15	NA	1.22	[1.16-1.28]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7517810-T	Research Support, N.I.H., Extramural	Meta-Analysis
1	172862234	rs9286879	A	G	rs9286879	18587394	2.00E-09	NA	1.19	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9286879-G	Research Support, N.I.H., Extramural	Meta-Analysis
1	172862234	rs9286879	A	G	rs9286879	23128233	6.00E-22	NA	1.13	[1.08-1.17]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9286879-G	Research Support, N.I.H., Extramural	Meta-Analysis
1	172862939	rs10489276	C	T	rs10489276	18587394	9.01E-08	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
1	172898377	rs12035082	T	C	rs12035082	17554261	2.00E-07		1.14	[1.02-1.27]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
1	190442971	rs2490271	G	A	rs2490271	17435756	3.44E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
1	191559356	rs10801047	A	T	rs10801047	17554261	3.00E-08		1.47	[1.22-1.76]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	192559646	rs10489873	G	A	rs10489873	22482804	7.42E-06	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
1	197727642	rs1998598	A	G	rs1998598	21102463	9.00E-09	NA	1.04	[1.00-1.09]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1998598-G	Research Support, N.I.H., Extramural	Meta-Analysis
1	197743506	rs1539414	G	A	rs1539414	20570966	4.70E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
1	200877562	rs7554511	C	A	rs7554511	21102463	2.00E-07	NA	1.14	[1.08-1.19]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7554511-C	Research Support, N.I.H., Extramural	Meta-Analysis
1	200935866	rs11584383	T	C	rs11584383	18587394	1.00E-11	NA	1.18	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11584383-T	Research Support, N.I.H., Extramural	Meta-Analysis
1	200960307	rs2297909	G	A	rs2297909	18587394	8.10E-10	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
1	204789624	rs2208843	G	A	rs2208843	22482804	5.83E-05	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
1	206939904	rs3024505	G	A	rs3024505	21102463	2.00E-14	NA	1.12	[1.07-1.17]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3024505-T	Research Support, N.I.H., Extramural	Meta-Analysis
1	209723420	rs6673693	T	G	rs6673693	17684544	6.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
1	226385623	rs10753415	T	C	rs10753415	18587394	5.08E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
1	228880021	rs1062060	C	T	rs1062060	20570966	4.20E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	5664008	rs11894081	G	T	rs11894081	23266558	4.00E-09	NA	1.22	[1.20-1.22]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11894081-T	Research Support, Non-U.S. Gov't	Comparative Study
2	21952204	rs6733000	C	T	rs6733000	17435756	3.03E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
2	23932461	rs2712102	C	T	rs2712102	20570966	8.40E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	25492467	rs13428812	A	G	rs13428812	21102463	9.00E-10	NA	1.06	[1.03-1.10]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs13428812-G	Research Support, N.I.H., Extramural	Meta-Analysis
2	27635463	rs1728918	A	G	rs1728918	23128233	5.00E-16	NA	1.12	[1.09-1.16]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1728918-A	Research Support, N.I.H., Extramural	Meta-Analysis
2	27730940	rs1260326	T	C	rs1260326	18587394	2.30E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
2	27741237	rs780094	T	C	rs780094	18587394	1.50E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
2	27742603	rs780093	T	C	rs780093	21102463	5.00E-11	NA	1.15	[1.10-1.21]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs780093-T	Research Support, N.I.H., Extramural	Meta-Analysis
2	28582597	rs10184619	C	T	rs10184619	22482804	5.85E-06	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
2	37599337	rs7582749	C	G	rs7582749	17684544	3.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
2	43806918	rs10495903	C	T	rs10495903	21102463	2.00E-14	NA	1.14	[1.09-1.20]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10495903-T	Research Support, N.I.H., Extramural	Meta-Analysis
2	56448266	rs10490395	A	C	rs10490395	17684544	4.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
2	61186829	rs13003464	A	G	rs13003464	18587394	1.57E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
2	61186829	rs13003464	A	G	rs13003464	22412388	5.00E-09	NA	1.05	[1.00-1.40]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs13003464-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	61217542	rs10188217	T	C	rs10188217	18587394	6.36E-08	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
2	61217542	rs10188217	T	C	rs10188217	21298027	1.00E-11	combined	NA	NA	3,230 European ancestry Crohn's disease cases; 768 European ancestry celiac disease cases; 6,251 European ancestry controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	61224259	rs10181042	C	T	rs10181042	21102463	7.00E-09	NA	1.14	[1.09-1.19]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10181042-T	Research Support, N.I.H., Extramural	Meta-Analysis
2	62551472	rs10865331	A	G	rs10865331	23128233	1.00E-09	NA	1.1	[1.06-1.13]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10865331-A	Research Support, N.I.H., Extramural	Meta-Analysis
2	62713533	rs6545946	C	T	rs6545946	22412388	7.00E-09	NA	1.16	[1.06-1.27]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6545946-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	65702803	rs840969	T	C	rs840969	23850713	8.59E-05	NA	1.18	[1.09-1.28]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs840969-T	Research Support, Non-U.S. Gov't	Validation Studies
2	66082204	rs2194782	A	G	rs2194782	20570966	1.60E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	102622376	rs4851527	A	G	rs4851527	22482804	2.26E-05	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
2	102971865	rs13015714	G	T	rs13015714	21298027	1.63E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	103019919	rs1035127	A	G	rs1035127	21298027	1.23E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	103024813	rs4851007	T	G	rs4851007	21298027	2.11E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	103035044	rs1420106	A	G	rs1420106	21298027	2.53E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	103038587	rs3755267	T	G	rs3755267	21298027	1.49E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	103049910	rs2041756	A	G	rs2041756	21298027	3.25E-05	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	103054449	rs2058660	G	A	rs2058660	21102463	2.00E-12	NA	1.19	[1.14-1.26]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2058660-G	Research Support, N.I.H., Extramural	Meta-Analysis
2	103063369	rs6708413	G	A	rs6708413	18587394	1.45E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
2	103063369	rs6708413	G	A	rs6708413	21298027	2.05E-05	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	103068787	rs7559479	G	A	rs7559479	21298027	3.03E-05	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	103070568	rs917997	T	C	rs917997	18587394	1.11E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
2	103070568	rs917997	T	C	rs917997	21298027	2.17E-05	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	103094213	rs759382	G	T	rs759382	21298027	2.03E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
2	123186585	rs10496586	C	T	rs10496586	17684544	3.90E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
2	125426455	rs4848966	T	G	rs4848966	23266558	7.55E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
2	145504693	rs7603516	T	G	rs7603516	17435756	3.10E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
2	160964700	rs10497212	T	G	rs10497212	17684544	7.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
2	161101169	rs2925757	G	A	rs2925757	17684544	2.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
2	165985503	rs17829596	T	C	rs17829596	20570966	5.70E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	180216731	rs13403289	C	A	rs13403289	23665963	4.10E-05	NA	1.67	NA	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	180216731	rs13403289	C	A	rs13403289	23665963	4.60E-05	NA	1.67	NA	239 European ancestry cases that required surgery within 5 year; 375 European ancestry cases that did not require surgery within 5 years	European(614)	ALL(614)	EUR(614)	ALL(614)	Crohn's disease (need for surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	181339431	rs934882	G	A	rs934882	20570966	4.30E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	198113157	rs2697290	A	G	rs2697290	20570966	9.80E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	198896895	rs6738825	A	G	rs6738825	21102463	4.00E-09	NA	1.06	[1.02-1.11]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6738825-A	Research Support, N.I.H., Extramural	Meta-Analysis
2	223930506	rs9283536	C	T	rs9283536	17684544	7.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
2	231091223	rs13397985	T	G	rs13397985	18587394	9.04E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
2	231097129	rs6716753	T	C	rs6716753	23128233	1.00E-16	NA	1.13	[1.09-1.18]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6716753-C	Research Support, N.I.H., Extramural	Meta-Analysis
2	231109329	rs6743984	T	C	rs6743984	18587394	2.48E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
2	231116874	rs7423615	C	T	rs7423615	21102463	3.00E-13	NA	1.12	[1.07-1.18]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7423615-T	Research Support, N.I.H., Extramural	Meta-Analysis
2	234158839	rs10210302	C	T	rs10210302	17554300	5.00E-14	NA	1.19	[1.01-1.41]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10210302-T	Multicenter Study	Research Support, N.I.H., Extramural
2	234173503	rs12994997	G	A	rs12994997	23128233	4.00E-70	NA	1.23	[1.19-1.27]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs12994997-A	Research Support, N.I.H., Extramural	Meta-Analysis
2	234180410	rs3828309	A	G	rs3828309	18587394	2.00E-32	NA	1.25	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3828309-G	Research Support, N.I.H., Extramural	Meta-Analysis
2	234183368	rs2241880	A	G	rs2241880	17435756	1.00E-13	NA	1.45	[1.27-1.64]	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2241880-G	Research Support, N.I.H., Extramural	Comparative Study
2	234183368	rs2241880	A	G	rs2241880	17684544	8.68E-07	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
2	234183368	rs2241880	A	G	rs2241880	18587394	4.61E-25	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
2	234183368	rs2241880	A	G	rs2241880	20570966	3.00E-06	NA	1.32	[1.18-1.47]	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	234183368	rs2241880	A	G	rs2241880	22412388	1.00E-12	NA	1.32	[1.24-1.41]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2241880-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
2	234184417	rs3792109	G	A	rs3792109	21102463	7.00E-41	NA	1.34	[1.29-1.40]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3792109-A	Research Support, N.I.H., Extramural	Meta-Analysis
2	234184417	rs3792109	G	A	rs3792109	22936669	5.00E-09	NA	1.38	NA	1,277 European ancestry cases; 1,488 European ancestry controls	European(2765)	ALL(2765)	EUR(2765)	ALL(2765)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3792109-A	Research Support, Non-U.S. Gov't	T
2	234210681	rs4663147	G	A	rs4663147	23850713	6.05E-05	NA	1.31	[1.15-1.49]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4663147-G	Research Support, Non-U.S. Gov't	Validation Studies
2	235446253	rs7592582	A	C	rs7592582	20570966	1.00E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
3	18706858	rs13073817	G	A	rs13073817	21102463	7.00E-09	NA	1.08	[1.03-1.13]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs13073817-A	Research Support, N.I.H., Extramural	Meta-Analysis
3	35539957	rs940070	C	G	rs940070	17684544	4.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	37574024	rs267567	G	A	rs267567	18587394	3.03E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
3	49326178	rs9874474	A	G	rs9874474	17804789	1.31E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49329090	rs4410472	A	T	rs4410472	17804789	1.53E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49343175	rs2230929	G	A,C,T	rs2230929	17804789	1.38E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49359943	rs9873994	T	C	rs9873994	17804789	1.63E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49366741	rs9863142	G	C	rs9863142	17804789	1.32E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49389842	rs17080528	C	T	rs17080528	17804789	8.75E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49406080	rs2878298	T	C	rs2878298	17804789	4.62E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	NA
3	49411404	rs7621003	T	C	rs7621003	17804789	4.76E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49416825	rs7648841	G	A	rs7648841	17804789	3.63E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49450864	rs6784820	A	G	rs6784820	18587394	1.20E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
3	49453834	rs6997	C	T	rs6997	17804789	3.16E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49459114	rs4855873	A	C	rs4855873	17804789	3.25E-15	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49463287	rs6446272	G	A	rs6446272	17804789	4.17E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49470668	rs7646366	G	A	rs7646366	17804789	5.82E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49497883	rs885592	T	G	rs885592	17804789	1.61E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
3	49499829	rs10865955	G	A	rs10865955	17804789	2.81E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49520958	rs1568661	A	G	rs1568661	17804789	1.92E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
3	49521974	rs4855864	C	T	rs4855864	17804789	2.03E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49524236	rs3924462	T	G	rs3924462	18587394	3.56E-08	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
3	49525962	rs4855861	G	T	rs4855861	17804789	1.53E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49535115	rs7637999	C	T	rs7637999	17804789	1.41E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49538799	rs11130199	T	C	rs11130199	17804789	1.85E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49557051	rs3870338	A	G	rs3870338	17804789	1.45E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49570882	rs1050088	T	C	rs1050088	17804789	1.40E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49580347	rs11720264	C	T	rs11720264	17804789	1.79E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49590770	rs3811697	C	T	rs3811697	17804789	3.19E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49626306	rs6446285	G	A	rs6446285	17804789	1.97E-04	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
3	49634696	rs9875617	G	A	rs9875617	17804789	1.95E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49649989	rs9827708	C	G	rs9827708	17804789	6.61E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49666964	rs1873625	C	A	rs1873625	17804789	6.61E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49675142	rs1873626	T	A	rs1873626	17804789	1.92E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49679072	rs2329021	G	A	rs2329021	17804789	2.69E-09	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49682311	rs9812791	G	A	rs9812791	17804789	1.61E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G,A
3	49696797	rs11718165	A	G	rs11718165	17804789	1.48E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
3	49701983	rs9858542	G	A	rs9858542	17554261	5.00E-08		1.17	[1.14-1.31]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49701983	rs9858542	G	A	rs9858542	17554300	4.00E-08	NA	1.09	[0.96-1.24]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9858542-A	Multicenter Study	Research Support, N.I.H., Extramural
3	49701983	rs9858542	G	A	rs9858542	18587394	3.55E-12	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
3	49714225	rs1131095	T	C	rs1131095	17804789	1.99E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49715446	rs4855881	G	A	rs4855881	17804789	1.09E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49719729	rs9822268	G	A	rs9822268	17804789	1.26E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49721532	rs3197999	G	A	rs3197999	18587394	1.00E-12	NA	1.2	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3197999-A	Research Support, N.I.H., Extramural	Meta-Analysis
3	49721532	rs3197999	G	A	rs3197999	21102463	6.00E-17	NA	1.22	[1.16-1.27]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3197999-A	Research Support, N.I.H., Extramural	Meta-Analysis
3	49772375	rs7649348	G	A	rs7649348	17804789	2.09E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
3	49788969	rs7372966	T	C	rs7372966	17804789	2.36E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49790544	rs7372725	C	A	rs7372725	17804789	1.52E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49807085	rs9859153	G	T	rs9859153	17804789	2.62E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49819102	rs11130221	C	G	rs11130221	17804789	2.33E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49842625	rs2234391	A	G	rs2234391	17804789	1.35E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C,T
3	49869158	rs695238	A	C	rs695238	17804789	1.09E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49882349	rs2247036	C	T	rs2247036	17804789	1.16E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49890613	rs2352974	C	T	rs2352974	17804789	2.02E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	49898000	rs2777888	A	G	rs2777888	17804789	1.32E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	49902544	rs9821675	A	G	rs9821675	17804789	2.57E-04	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G,A
3	49924424	rs11713193	G	A	rs11713193	17804789	2.57E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
3	49936102	rs2230590	T	C	rs2230590	17804789	3.91E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	49949834	rs7634084	A	T	rs7634084	17804789	3.20E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
3	50210289	rs1005678	C	G	rs1005678	17804789	9.95E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	50212512	rs2624833	G	T	rs2624833	17804789	5.45E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	59736299	rs812965	T	C	rs812965	17684544	4.80E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
3	106624294	rs1517605	T	C	rs1517605	21298027	1.98E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
3	106639719	rs1568206	C	G	rs1568206	21298027	2.90E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
3	113272208	rs1513287	G	A	rs1513287	17684544	9.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	113680951	rs1386478	A	G	rs1386478	22482804	7.00E-06	NA	1.12	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
3	121551570	rs12695416	A	G	rs12695416	17804789	6.31E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
3	132192129	rs9829140	T	C	rs9829140	18587394	6.21E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
3	133575865	rs7644124	T	C	rs7644124	17684544	2.90E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	138992418	rs10513059	C	T	rs10513059	17684544	2.07E-06	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	140169657	rs6439924	A	C	rs6439924	17435756	6.00E-05	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
3	175151789	rs10490876	C	T	rs10490876	17684544	3.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
3	192595307	rs2367129	A	C	rs2367129	17684544	1.90E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
4	6206784	rs10003892	G	A	rs10003892	17804789	3.65E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
4	6213622	rs4274923	G	A	rs4274923	17804789	3.00E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
4	6216955	rs13132796	C	G	rs13132796	17804789	5.83E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
4	6219929	rs4234723	A	G	rs4234723	17804789	4.89E-04	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
4	6222105	rs908016	A	T	rs908016	17804789	2.81E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
4	7531319	rs11931489	G	A	rs11931489	18587394	5.27E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
4	37967083	rs10517460	A	C	rs10517460	17684544	1.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
4	38322491	rs76273539	G	T	rs76273539	23266558	8.35E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38324906	rs4453942	A	C	rs4453942	23266558	4.68E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38325003	rs1906295	G	A	rs1906295	23266558	4.81E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38325036	rs6856616	T	C	rs6856616	23266558	3.57E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38325036	rs6856616	T	C	rs6856616	23850713	4.00E-14	NA	1.43	[1.31-1.57]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6856616-C	Research Support, Non-U.S. Gov't	Validation Studies
4	38325062	rs1906296	G	A	rs1906296	23266558	6.52E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38325105	rs1906297	T	C	rs1906297	23266558	5.80E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38327654	rs6822641	A	G	rs6822641	23266558	5.85E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38328777	rs6829875	A	G	rs6829875	23266558	5.94E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38330016	rs73243350	G	A	rs73243350	23266558	1.15E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38335067	rs73243351	G	A	rs73243351	23266558	1.51E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38335823	rs1487630	C	T	rs1487630	23266558	1.00E-11	NA	1.33	[1.22-1.44]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1487630-T	Research Support, Non-U.S. Gov't	Comparative Study
4	38337114	rs75918970	C	T	rs75918970	23266558	1.84E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38345898	rs73243354	A	C	rs73243354	23266558	1.16E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38361416	rs55843528	G	A	rs55843528	23266558	1.72E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38363406	rs6846728	T	G	rs6846728	23266558	1.51E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38364637	rs62294142	G	A	rs62294142	23266558	3.19E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38367910	rs55818238	T	C	rs55818238	23266558	1.12E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38369359	rs73243363	C	T	rs73243363	23266558	2.14E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	38379303	rs12330996	C	T	rs12330996	23266558	1.88E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	41753130	rs16853571	A	C	rs16853571	17435756	2.40E-07	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
4	48363983	rs6837335	A	G	rs6837335	23128233	2.00E-08	NA	1.09	[1.05-1.12]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6837335-G	Research Support, N.I.H., Extramural	Meta-Analysis
4	76134763	rs1845983	G	A	rs1845983	17684544	4.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
4	76161222	rs7681167	A	G	rs7681167	17684544	2.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
4	102865304	rs13126505	G	A	rs13126505	23128233	2.00E-12	NA	1.17	[1.10-1.25]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs13126505-A	Research Support, N.I.H., Extramural	Meta-Analysis
4	104665738	rs233991	C	A	rs233991	20570966	5.40E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
4	106106353	rs10010325	C	A	rs10010325	18587394	5.03E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
4	110175673	rs115921721	A	G	rs115921721	23266558	7.48E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
4	134471862	rs1493517	C	T	rs1493517	17684544	5.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
4	134487011	rs9307696	G	C	rs9307696	17684544	5.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
4	134530386	rs925084	T	G	rs925084	17684544	1.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
4	134536988	rs7674505	G	A	rs7674505	17684544	2.63E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
4	134554855	rs2660727	G	A	rs2660727	17684544	3.95E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
4	134600991	rs7700170	G	A	rs7700170	17684544	2.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
4	134619611	rs2660693	C	G	rs2660693	17684544	2.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
4	138225217	rs1559781	C	T	rs1559781	17684544	4.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
4	149835012	rs853727	C	T	rs853727	17684544	2.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
4	157145352	rs10517634	C	T	rs10517634	17684544	5.50E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
4	187201211	rs5974	A	G	rs5974	18587394	7.81E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
4	187210620	rs4253431	G	A	rs4253431	18587394	1.33E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
5	16178920	rs342549	G	A	rs342549	23266558	4.84E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
5	25781613	rs2928266	T	C	rs2928266	17684544	2.80E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	37913544	rs10512670	A	C	rs10512670	18587394	2.41E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
5	40319877	rs1445002	C	A	rs1445002	17684544	3.94E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	40320006	rs348601	T	C	rs348601	17447842	5.10E-07	NA	NA	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	40372223	rs7725523	A	G	rs7725523	17684544	7.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	40386555	rs1002922	T	C	rs1002922	17447842	1.70E-09	NA	NA	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	40392728	rs4613763	T	C	rs4613763	17435756	1.21E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
5	40392728	rs4613763	T	C	rs4613763	17447842	1.20E-09	NA	NA	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	40392728	rs4613763	T	C	rs4613763	18587394	7.00E-27	NA	1.32	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4613763-C	Research Support, N.I.H., Extramural	Meta-Analysis
5	40393605	rs10512734	A	G	rs10512734	17447842	9.20E-11	NA	NA	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	40393852	rs1992662	A	G	rs1992662	17684544	1.56E-07	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	40401509	rs17234657	T	G	rs17234657	17554300	2.00E-12	NA	1.54	[1.34-1.76]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs17234657-G	Multicenter Study	Research Support, N.I.H., Extramural
5	40401509	rs17234657	T	G	rs17234657	18587394	3.41E-27	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
5	40410584	rs11742570	T	C	rs11742570	21102463	7.00E-36	NA	1.33	[1.27-1.39]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11742570-C	Research Support, N.I.H., Extramural	Meta-Analysis
5	40410584	rs11742570	T	C	rs11742570	22936669	1.00E-06	NA	1.32	NA	1,277 European ancestry cases; 1,488 European ancestry controls	European(2765)	ALL(2765)	EUR(2765)	ALL(2765)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11742570-C	Research Support, Non-U.S. Gov't	C
5	40415067	rs1992660	C	T	rs1992660	17684544	4.00E-07	NA	1.42	[1.24-1.67]	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	40431183	rs1373692	A	C	rs1373692	17435756	5.37E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
5	40431183	rs1373692	A	C	rs1373692	17447842	2.00E-12	NA	1.46	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	40437948	rs9292777	C	T	rs9292777	17554261	3.00E-18	NA	1.34	[1.20-1.50]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	40437948	rs9292777	C	T	rs9292777	22412388	2.00E-11	NA	1.37	[1.28-1.48]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9292777-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	40463739	rs4957300	T	C	rs4957300	17684544	2.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	40477515	rs4495224	C	A	rs4495224	17447842	2.20E-07	NA	NA	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	40487270	rs7725052	C	T	rs7725052	17684544	3.24E-06	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	40502932	rs1553575	A	G	rs1553575	17684544	1.68E-06	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	40554269	rs6451525	C	T	rs6451525	17684544	1.64E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	45266589	rs4866929	A	G	rs4866929	20570966	9.10E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	55438851	rs10065637	C	T	rs10065637	23128233	4.00E-12	NA	1.12	[1.08-1.17]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10065637-C	Research Support, N.I.H., Extramural	Meta-Analysis
5	72551134	rs7702331	A	G	rs7702331	21102463	6.00E-12	NA	1.12	[1.07-1.17]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7702331-A	Research Support, N.I.H., Extramural	Meta-Analysis
5	72551134	rs7702331	A	G	rs7702331	23128233	6.00E-10	NA	1.09	[1.05-1.13]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7702331-A	Research Support, N.I.H., Extramural	Meta-Analysis
5	84758140	rs247660	A	C	rs247660	18587394	7.30E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
5	94649904	rs255969	C	T	rs255969	17804789	1.41E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	96244549	rs2549794	C	T	rs2549794	21102463	1.00E-10	NA	1.05	[1.02-1.09]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2549794-C	Research Support, N.I.H., Extramural	Meta-Analysis
5	101946798	rs7705924	A	G	rs7705924	22412388	2.00E-08	NA	1.48	[1.17-1.87]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7705924-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	115022257	rs249721	A	G	rs249721	17684544	2.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	115891083	rs254079	A	G	rs254079	18587394	2.55E-17	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
5	129149447	rs10053519	A	G	rs10053519	22482804	4.42E-06	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
5	129436666	rs10050470	G	A	rs10050470	17804789	5.07E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	129439574	rs6858978	A	G	rs6858978	17804789	7.14E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	129669537	rs6595948	C	T	rs6595948	17804789	4.93E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	129684556	rs6869287	G	T	rs6869287	17804789	8.81E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130104076	rs10051722	A	C	rs10051722	17804789	5.38E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	130603119	rs6596008	A	G	rs6596008	17804789	3.87E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130611700	rs1468328	A	T	rs1468328	17804789	5.56E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130616792	rs12513768	G	A	rs12513768	17804789	2.96E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	130626621	rs11242070	A	G	rs11242070	17804789	2.34E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130657418	rs2549011	G	C	rs2549011	17804789	2.31E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	NA
5	130657418	rs35707316	G	GC	rs2549011	17804789	2.31E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	NA
5	130674076	rs4706020	G	A	rs4706020	17804789	3.61E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	130688378	rs798407	C	G	rs798407	17804789	2.85E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	130709422	rs30735	G	A	rs30735	17804789	1.94E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130740005	rs257391	C	A	rs257391	17804789	1.15E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130753077	rs10040442	C	G	rs10040442	17804789	5.83E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	130769785	rs6596024	C	A	rs6596024	17804789	3.03E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130773561	rs6896132	G	C	rs6896132	17804789	1.78E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	130802970	rs3776027	T	C	rs3776027	17804789	2.89E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130808198	rs31241	T	C	rs31241	17804789	2.10E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130811146	rs31240	T	A	rs31240	17804789	4.25E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130813377	rs31239	T	G	rs31239	17804789	2.09E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130824536	rs31258	G	A	rs31258	17804789	3.70E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130828649	rs39600	A	T	rs39600	17804789	3.70E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130831365	rs40400	T	C	rs40400	17804789	4.25E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130833433	rs31252	T	C	rs31252	17804789	2.19E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130837077	rs7720194	T	C	rs7720194	17804789	2.37E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130855000	rs4705890	T	C	rs4705890	17804789	2.32E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130867404	rs3776013	C	T	rs3776013	17804789	2.42E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	130872520	rs994453	T	G	rs994453	17804789	2.05E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130875538	rs3776006	C	T	rs3776006	17804789	2.10E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	130891101	rs984616	C	T	rs984616	17804789	7.10E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	130902196	rs9327616	C	T	rs9327616	17804789	2.77E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	130907189	rs8180462	T	C	rs8180462	17804789	2.67E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130911578	rs11750704	C	A	rs11750704	17804789	4.25E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	130918037	rs9687376	A	C	rs9687376	17804789	2.77E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130920831	rs2021774	G	A	rs2021774	17804789	5.36E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	130926822	rs3756291	T	C	rs3756291	17804789	6.15E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130935777	rs11242084	T	C	rs11242084	17804789	2.71E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130942624	rs1422870	G	T	rs1422870	17804789	1.13E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	130951750	rs3756290	A	G	rs3756290	17804789	8.13E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130957992	rs3776001	T	A	rs3776001	17804789	2.13E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	130966026	rs6872682	T	C	rs6872682	17804789	3.13E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130982194	rs3756289	A	G	rs3756289	17804789	2.64E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	130990384	rs26003	T	C	rs26003	17804789	2.64E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131006082	rs27450	A	G	rs27450	17804789	2.38E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131013815	rs26010	G	A	rs26010	17804789	2.73E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	131048122	rs32112	G	A	rs32112	17804789	1.82E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	131055546	rs548635	T	G	rs548635	17804789	2.68E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	131072410	rs10051003	C	T	rs10051003	17804789	2.10E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	131099227	rs1019122	C	T	rs1019122	17804789	2.22E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	131107381	rs3775992	T	G	rs3775992	17804789	1.92E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131114979	rs10042334	A	T	rs10042334	17804789	2.07E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131118943	rs9327621	T	C	rs9327621	17804789	2.04E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C,T
5	131135478	rs3756287	A	G	rs3756287	17804789	2.37E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	131146993	rs4705901	T	C	rs4705901	17804789	8.41E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	131152575	rs11242095	T	C	rs11242095	17804789	2.07E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	131165216	rs2133706	T	G	rs2133706	17804789	2.07E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	131174215	rs10069521	A	G	rs10069521	17804789	1.86E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131202457	rs1875176	G	A	rs1875176	17804789	2.07E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	131258378	rs113905823	A	AC	rs630044	17804789	8.55E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	131258378	rs630044	A	C	rs630044	17804789	8.55E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	131267609	rs578637	G	A	rs578637	17804789	2.03E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131269453	rs519240	G	A	rs519240	17804789	2.10E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131275509	rs667437	G	A	rs667437	17804789	2.07E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131286708	rs648304	T	C	rs648304	17804789	8.09E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	131305384	rs40819	G	T	rs40819	17804789	1.84E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131318788	rs399714	C	T	rs399714	17804789	2.44E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	131343017	rs10040809	A	C	rs10040809	17804789	6.41E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131348878	rs246998	A	G	rs246998	17804789	8.63E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	131350903	rs555662	G	A	rs555662	17804789	9.64E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
5	131363979	rs17132324	A	G	rs17132324	17804789	2.91E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131369168	rs3916442	G	A	rs3916442	17804789	2.10E-09	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131371999	rs1858074	A	G	rs1858074	17804789	8.97E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131379656	rs7728344	C	T	rs7728344	17804789	3.29E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	131397202	rs31481	G	A	rs31481	17804789	4.13E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	131401334	rs246844	G	A	rs246844	17804789	1.41E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	131402738	rs3091338	C	T	rs3091338	22412388	4.00E-08	NA	1.23	[1.08-1.42]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3091338-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	131405027	rs31474	T	C	rs31474	17804789	2.91E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	131420249	rs3864277	G	A	rs3864277	17804789	1.17E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	131575338	rs12521097	G	A	rs12521097	17804789	1.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	131577894	rs2136187	T	C	rs2136187	17804789	1.88E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131582356	rs3844312	C	T	rs3844312	17804789	1.10E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	131586480	rs3763112	A	G	rs3763112	17804789	1.79E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131665423	rs272888	T	C	rs272888	17804789	4.79E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	131676320	rs1050152	C	T	rs1050152	17804789	2.14E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	131676320	rs1050152	C	T	rs1050152	18587394	1.54E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
5	131742228	rs6596075	G	C	rs6596075	17554300	3.00E-06	NA	1.55	[1.00-2.39]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6596075-C	Multicenter Study	Research Support, N.I.H., Extramural
5	131770805	rs2188962	C	T	rs2188962	18587394	2.00E-18	NA	1.25	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2188962-T	Research Support, N.I.H., Extramural	Meta-Analysis
5	131770805	rs2188962	C	T	rs2188962	20570966	1.00E-07	NA	1.36	[1.21-1.52]	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	131784393	rs12521868	G	T	rs12521868	21102463	1.00E-20	NA	1.23	[1.18-1.28]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs12521868-T	Research Support, N.I.H., Extramural	Meta-Analysis
5	131801947	rs2522057	G	C	rs2522057	17804789	3.16E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	131804347	rs2248116	C	A	rs2248116	17804789	3.16E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	131833599	rs736801	C	T	rs736801	17804789	1.69E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	136447574	rs1859346	A	C	rs1859346	17684544	7.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	141479065	rs11167764	A	C	rs11167764	21102463	2.00E-09	NA	1.06	[1.02-1.11]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11167764-C	Research Support, N.I.H., Extramural	Meta-Analysis
5	146046418	rs3096085	G	A	rs3096085	17684544	8.50E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
5	150223387	rs13361189	T	C	rs13361189	17554261	2.00E-10	NA	1.38	[1.15-1.66]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
5	150223387	rs13361189	T	C	rs13361189	18587394	7.33E-16	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
5	150240076	rs1000113	C	T	rs1000113	17554300	3.00E-07	NA	1.54	[1.31-1.82]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1000113-T	Multicenter Study	Research Support, N.I.H., Extramural
5	150258867	rs11747270	A	G	rs11747270	18587394	3.00E-16	NA	1.33	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11747270-G	Research Support, N.I.H., Extramural	Meta-Analysis
5	150270420	rs7714584	A	G	rs7714584	21102463	8.00E-19	NA	1.37	[1.28-1.47]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7714584-G	Research Support, N.I.H., Extramural	Meta-Analysis
5	158787385	rs6556412	G	A	rs6556412	21102463	5.00E-14	NA	1.18	[1.13-1.24]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6556412-A	Research Support, N.I.H., Extramural	Meta-Analysis
5	158814533	rs10045431	A	C	rs10045431	18587394	4.00E-13	NA	1.11	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10045431-C	Research Support, N.I.H., Extramural	Meta-Analysis
5	158814533	rs10045431	A	C	rs10045431	20570966	7.00E-08	NA	1.45	[1.27-1.64]	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
5	158822645	rs6887695	G	C	rs6887695	17554261	9.00E-06		1.26	[1.12-1.41]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
5	173279842	rs359457	C	T	rs359457	21102463	3.00E-12	NA	1.08	[1.04-1.12]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs359457-T	Research Support, N.I.H., Extramural	Meta-Analysis
5	173337853	rs17695092	T	G	rs17695092	23128233	5.00E-09	NA	1.1	[1.05-1.14]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs17695092-T	Research Support, N.I.H., Extramural	Meta-Analysis
5	177802373	rs12519834	G	A	rs12519834	20570966	5.00E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	880234	rs7768444	C	A	rs7768444	20570966	5.60E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	3433318	rs17309827	T	G	rs17309827	18587394	3.70E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	3433318	rs17309827	T	G	rs17309827	21102463	7.00E-09	NA	1.1	[1.05-1.16]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs17309827-T	Research Support, N.I.H., Extramural	Meta-Analysis
6	3434242	rs4959830	G	A	rs4959830	18587394	2.83E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	5151247	rs12529198	A	G	rs12529198	18587394	3.48E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	20689945	rs7748720	G	A	rs7748720	18587394	1.64E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	20728731	rs6908425	T	C	rs6908425	18587394	9.00E-10	NA	1.21	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6908425-C	Research Support, N.I.H., Extramural	Meta-Analysis
6	20728731	rs6908425	T	C	rs6908425	21102463	1.00E-08	NA	1.17	[1.11-1.23]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6908425-C	Research Support, N.I.H., Extramural	Meta-Analysis
6	21430728	rs12663356	T	C	rs12663356	23128233	4.00E-12	NA	1.1	[1.06-1.13]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs12663356-C	Research Support, N.I.H., Extramural	Meta-Analysis
6	21457950	rs11758386	C	T	rs11758386	18587394	3.40E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	21470419	rs7759649	C	T	rs7759649	18587394	5.02E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	28791202	rs10484543	A	T	rs10484543	17684544	9.36E-06	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
6	28968930	rs9257453	A	G	rs9257453	17684544	3.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
6	29234510	rs10484545	C	G	rs10484545	17684544	2.84E-07	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
6	29723161	rs9258260	C	T	rs9258260	22412388	2.00E-10	NA	1.45	[1.21-1.68]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9258260-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	30955681	rs1634731	G	A	rs1634731	23266558	2.45E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31085770	rs3094212	G	A	rs3094212	23266558	1.16E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31085770	rs551894425	G	A	rs3094212	23266558	1.16E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31111356	rs9263739	C	T	rs9263739	23266558	7.11E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31114573	rs2240064	G	A	rs2240064	23266558	5.23E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31119589	rs1265109	G	T	rs1265109	23266558	2.05E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31125569	rs2239524	T	G	rs2239524	23266558	3.03E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31126944	rs3094187	C	T	rs3094187	23266558	1.37E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31130593	rs1419881	G	A	rs1419881	23266558	2.36E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31133943	rs3130932	C	A	rs3130932	23266558	9.90E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31134888	rs3130931	T	C	rs3130931	23266558	3.43E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31136453	rs3130501	A	G	rs3130501	23266558	2.22E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31142245	rs3094188	C	A	rs3094188	23266558	7.00E-07	NA	1.61	[1.33-1.94]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3094188-C	Research Support, Non-U.S. Gov't	Comparative Study
6	31187075	rs3130467	C	T	rs3130467	23266558	7.90E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31209510	rs3130712	C	T	rs3130712	23266558	7.24E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31241127	rs13207315	T	C	rs13207315	23266558	6.72E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31243884	rs3130696	G	A	rs3130696	23266558	1.65E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31245736	rs6906846	A	G	rs6906846	23266558	2.52E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31263751	rs2894207	T	C	rs2894207	23665963	2.90E-05	NA	1.6	[1.30-2.10]	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs2894207-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	31271157	rs7750269	A	G	rs7750269	23266558	5.52E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31272157	rs9368675	G	A	rs9368675	23266558	5.47E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31274380	rs9264942	T	C	rs9264942	23128233	5.00E-28	NA	1.15	[1.11-1.18]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9264942-C	Research Support, N.I.H., Extramural	Meta-Analysis
6	31275174	rs396243	T	C	rs396243	23266558	5.63E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31308630	rs9265797	G	A	rs9265797	23266558	5.06E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31348580	rs9266689	A	G	rs9266689	23266558	5.54E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31349922	rs9266722	C	T	rs9266722	23266558	9.80E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31436789	rs2523674	A	G	rs2523674	23266558	3.04E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31489644	rs3132454	A	G	rs3132454	23266558	1.09E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31542308	rs1799964	T	C	rs1799964	21102463	4.00E-11	NA	1.19	[1.13-1.25]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1799964-C	Research Support, N.I.H., Extramural	Meta-Analysis
6	31566204	rs2509217	C	T	rs2509217	23266558	5.70E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	31575276	rs9348876	C	T	rs9348876	22936669	3.00E-06	NA	1.41	[1.22-1.63]	1,277 European ancestry cases; 1,488 European ancestry controls	European(2765)	ALL(2765)	EUR(2765)	ALL(2765)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9348876-T	Research Support, Non-U.S. Gov't	T
6	31917540	rs4151657	T	C	rs4151657	23266558	3.88E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32050067	rs185819	T	C	rs185819	23266558	2.08E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32071893	rs3134954	C	T	rs3134954	23266558	5.42E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32144530	rs2071290	C	T	rs2071290	23266558	8.61E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32147696	rs3130349	G	A	rs3130349	23266558	8.58E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32149816	rs3134940	T	C	rs3134940	23266558	1.45E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32160153	rs2269420	C	A,G,T	rs2269420	23266558	8.45E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32186872	rs2256594	A	G	rs2256594	23266558	6.10E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32188823	rs8192585	G	A	rs8192585	23266558	6.12E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32191339	rs3830041	C	T	rs3830041	23266558	4.26E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32192560	rs2267644	G	A	rs2267644	23266558	2.56E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32199144	rs377763	C	A	rs377763	23266558	9.18E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32205045	rs549182	G	A	rs549182	23266558	6.43E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32205110	rs9267911	T	C	rs9267911	23266558	3.00E-07	NA	1.5	[1.29-1.76]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9267911-T	Research Support, Non-U.S. Gov't	Comparative Study
6	32209027	rs382259	T	C	rs382259	23266558	1.83E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32315727	rs910049	T	C	rs910049	23266558	5.44E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32321597	rs1265761	A	G	rs1265761	23266558	6.12E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32336766	rs3129939	A	G	rs3129939	23266558	1.29E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32373232	rs10947261	G	T	rs10947261	23850713	3.00E-12	NA	1.36	[1.25-1.49]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10947261-T	Research Support, Non-U.S. Gov't	Validation Studies
6	32376471	rs3763313	A	C	rs3763313	18587394	2.60E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	32409530	rs3129882	G	A	rs3129882	23266558	4.79E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32411523	rs2239804	T	C	rs2239804	23266558	8.86E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32569691	rs477515	G	A	rs477515	23266558	2.28E-07	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32570400	rs2516049	T	C	rs2516049	23266558	2.33E-07	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32577380	rs660895	A	G	rs660895	23266558	2.04E-10	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32578052	rs532098	G	A	rs532098	23266558	5.43E-08	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32586854	rs9271366	G	A	rs9271366	23266558	2.80E-09	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32586854	rs9271366	G	A	rs9271366	23850713	5.00E-12	NA	1.66	[1.44-1.92]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9271366-A	Research Support, Non-U.S. Gov't	Validation Studies
6	32627714	rs1063355	T	G	rs1063355	23266558	2.65E-07	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32652317	rs7755224	A	G,T	rs7755224	23266558	9.93E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32658310	rs9469220	G	A	rs9469220	17554300	2.00E-06	NA	1.14	[0.98-1.32]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9469220-A	Multicenter Study	Research Support, N.I.H., Extramural
6	32659878	rs9275224	A	G	rs9275224	23266558	2.48E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32663564	rs5000634	A	G	rs5000634	23266558	6.99E-08	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32663851	rs6457617	C	T	rs6457617	23266558	7.41E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32665728	rs9275312	A	G	rs9275312	23266558	7.20E-09	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32666822	rs9275328	C	T	rs9275328	23266558	8.28E-09	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32668296	rs9275371	T	C	rs9275371	23266558	1.10E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32668526	rs9275374	C	T	rs9275374	23266558	9.55E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32669156	rs9275390	T	C	rs9275390	23266558	8.88E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32669439	rs9275393	G	A	rs9275393	23266558	8.69E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32669767	rs2647050	T	C	rs2647050	23266558	5.95E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32669955	rs9275406	G	T	rs9275406	23266558	8.69E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32670000	rs2858308	G	T	rs2858308	23266558	7.14E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32670037	rs9275407	G	T	rs9275407	23266558	8.69E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32670110	rs9275408	T	C	rs9275408	23266558	8.14E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32670244	rs9275418	A	G	rs9275418	23266558	8.44E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32670255	rs2856718	C	T	rs2856718	23266558	6.26E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32670576	rs9275424	A	G	rs9275424	23266558	8.69E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32670874	rs9275425	C	A	rs9275425	23266558	8.60E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32670915	rs9275427	C	T	rs9275427	23266558	8.41E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32670956	rs2856705	C	T	rs2856705	23266558	7.03E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32670978	rs9275428	A	G	rs9275428	23266558	8.60E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32671103	rs13192471	T	C	rs13192471	23266558	5.67E-08	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32671521	rs9275439	T	C	rs9275439	23266558	8.69E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32677912	rs9275563	C	T	rs9275563	23266558	1.63E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32678999	rs9275572	A	G	rs9275572	23266558	1.38E-09	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32679690	rs3129727	C	T	rs3129727	23266558	4.71E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32680928	rs7765379	T	G	rs7765379	23266558	9.00E-59	NA	1.93	[1.78-2.09]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7765379-G	Research Support, Non-U.S. Gov't	Comparative Study
6	32680970	rs7745656	G	T	rs7745656	23266558	1.53E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32681161	rs2858332	G	T	rs2858332	23266558	1.57E-10	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32681277	rs2858331	A	G	rs2858331	18587394	2.17E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	32681277	rs2858331	A	G	rs2858331	23266558	2.02E-07	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32685685	rs3104398	G	A	rs3104398	23266558	3.19E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32685865	rs9275653	G	A	rs9275653	23266558	4.33E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32699515	rs2859099	C	T	rs2859099	23266558	2.94E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32702449	rs2859078	A	G	rs2859078	23266558	6.49E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32711178	rs17500468	A	G	rs17500468	23266558	5.94E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32722186	rs10807113	C	A	rs10807113	23266558	8.65E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32723917	rs7756516	C	T	rs7756516	23266558	8.77E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32741742	rs2857210	A	G	rs2857210	23266558	7.01E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32784676	rs2071554	C	T	rs2071554	23266558	3.20E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32788511	rs9784758	T	C	rs9784758	23266558	3.01E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32797684	rs241437	A	G	rs241437	23266558	2.06E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32818678	rs2071538	G	A	rs2071538	23266558	3.91E-09	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32941910	rs620202	G	T	rs620202	23266558	3.88E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32944746	rs11908	G	A	rs11908	23266558	2.32E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32950050	rs565876	G	A	rs565876	23266558	2.79E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32955976	rs188245	A	G	rs188245	23266558	2.84E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	32962420	rs206767	C	A	rs206767	23266558	6.40E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33058952	rs10484569	G	A	rs10484569	23266558	2.38E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33060118	rs2281388	G	A	rs2281388	23266558	3.25E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33077776	rs6457713	C	T	rs6457713	23266558	2.38E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33079166	rs9380343	C	T	rs9380343	23266558	5.94E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33086448	rs1883414	G	A	rs1883414	23266558	6.11E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33097614	rs3129269	C	A	rs3129269	23266558	2.48E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33098966	rs2294478	C	A	rs2294478	23266558	1.12E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33099210	rs2294472	A	G	rs2294472	23266558	2.09E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33114171	rs1003979	T	C	rs1003979	23266558	1.09E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33138021	rs9368758	G	A	rs9368758	23266558	4.82E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33141253	rs9277932	T	G	rs9277932	23266558	2.29E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33141280	rs2855430	G	A	rs2855430	23266558	3.76E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33142539	rs3762013	G	A	rs3762013	23266558	2.38E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33154656	rs2855459	G	A	rs2855459	23266558	3.47E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33158898	rs2269346	C	T	rs2269346	23266558	4.82E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33202640	rs213220	C	T	rs213220	23266558	1.32E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33252115	rs455567	G	A	rs455567	23266558	9.02E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	33764033	rs751728	C	T	rs751728	23850713	1.00E-08	NA	1.32	[1.20-1.45]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs751728-T	Research Support, Non-U.S. Gov't	Validation Studies
6	34961360	rs3800440	G	A	rs3800440	23266558	1.70E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	35162141	rs11755266	C	T	rs11755266	23266558	8.47E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	35206553	rs732594	C	A	rs732594	23266558	7.65E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	35805133	rs17704843	G	A	rs17704843	23266558	4.95E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	57217336	rs12209200	C	T	rs12209200	20570966	1.80E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	70912835	rs10498871	C	T	rs10498871	17684544	5.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
6	81473184	rs13201732	C	G	rs13201732	17804789	8.32E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
6	88776981	rs806438	T	A	rs806438	18587394	1.00E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	90973159	rs1847472	C	A	rs1847472	21102463	5.00E-09	NA	1.07	[1.03-1.11]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1847472-G	Research Support, N.I.H., Extramural	Meta-Analysis
6	91082136	rs4707614	G	A	rs4707614	17684544	7.80E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
6	92576591	rs1546210	C	A	rs1546210	17684544	4.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
6	106435025	rs6568421	A	G	rs6568421	21102463	4.00E-08	NA	1.13	[1.07-1.18]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6568421-G	Research Support, N.I.H., Extramural	Meta-Analysis
6	106435269	rs7746082	G	C	rs7746082	18587394	2.00E-10	NA	1.17	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7746082-C	Research Support, N.I.H., Extramural	Meta-Analysis
6	118124150	rs495662	G	A	rs495662	18587394	3.05E-16	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	127456122	rs9491697	A	G	rs9491697	23128233	4.00E-10	NA	1.08	[1.04-1.11]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9491697-G	Research Support, N.I.H., Extramural	Meta-Analysis
6	128245765	rs13204742	G	T	rs13204742	23128233	8.00E-15	NA	1.17	[1.12-1.23]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs13204742-T	Research Support, N.I.H., Extramural	Meta-Analysis
6	149577079	rs7758080	A	G	rs7758080	18587394	4.39E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	159465977	rs1738074	T	C	rs1738074	21298027	1.53E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
6	159490436	rs212388	C	T	rs212388	21102463	2.00E-11	NA	1.1	[1.05-1.14]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs212388-G	Research Support, N.I.H., Extramural	Meta-Analysis
6	159490436	rs212388	C	T	rs212388	21298027	2.00E-10	combined	NA	NA	3,230 European ancestry Crohn's disease cases; 768 European ancestry celiac disease cases; 6,251 European ancestry controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
6	159490436	rs212388	C	T	rs212388	23128233	3.00E-14	NA	1.11	[1.07-1.14]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs212388-C	Research Support, N.I.H., Extramural	Meta-Analysis
6	164020325	rs9346964	G	A	rs9346964	23665963	1.80E-05	NA	1.7	[1.30-2.10]	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs9346964-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	167371110	rs2149085	T	C	rs2149085	23850713	8.00E-12	NA	1.34	[1.23-1.45]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2149085-T	Research Support, Non-U.S. Gov't	Validation Studies
6	167383972	rs429083	T	C	rs429083	23266558	1.11E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	167398071	rs394522	A	C	rs394522	23850713	9.83E-11	NA	1.32	[1.21-1.43]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs394522-C	Research Support, Non-U.S. Gov't	Validation Studies
6	167406633	rs415890	G	C	rs415890	21102463	3.00E-12	NA	1.17	[1.12-1.22]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs415890-C	Research Support, N.I.H., Extramural	Meta-Analysis
6	167411008	rs400837	T	C	rs400837	23266558	1.83E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	167435325	rs7749278	T	C	rs7749278	18587394	5.80E-10	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
6	167437988	rs2301436	C	T	rs2301436	18587394	1.00E-12	NA	1.21	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2301436-T	Research Support, N.I.H., Extramural	Meta-Analysis
6	167437988	rs2301436	C	T	rs2301436	20570966	6.00E-08	NA	1.37	[1.22-1.53]	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
6	167461562	rs10484530	C	T	rs10484530	23266558	8.35E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
6	169912559	rs2997887	A	G	rs2997887	20570966	3.80E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	3232378	rs10272892	T	C	rs10272892	23665963	3.50E-05	NA	1.67	NA	239 European ancestry cases that required surgery within 5 year; 375 European ancestry cases that did not require surgery within 5 years	European(614)	ALL(614)	EUR(614)	ALL(614)	Crohn's disease (need for surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	4912398	rs4720435	G	T	rs4720435	20570966	2.80E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	10372184	rs891854	T	C	rs891854	20570966	1.60E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	15041529	rs10255000	T	C	rs10255000	17684544	8.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
7	17405718	rs7780687	A	G	rs7780687	23665963	2.70E-05	NA	2	[1.40-2.80]	239 European ancestry cases that required surgery within 5 year; 375 European ancestry cases that did not require surgery within 5 years	European(614)	ALL(614)	EUR(614)	ALL(614)	Crohn's disease (need for surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs7780687-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	21800459	rs6461599	A	G	rs6461599	17684544	7.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
7	22202485	rs1981601	T	C	rs1981601	20570966	5.80E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	24951382	rs134	G	A	rs134	17804789	2.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
7	26597211	rs6957717	A	G	rs6957717	23665963	4.91E-05	NA	1.67	NA	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	26892440	rs10486483	G	A	rs10486483	23128233	3.00E-08	NA	1.09	[1.05-1.13]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10486483-A	Research Support, N.I.H., Extramural	Meta-Analysis
7	28180556	rs864745	T	C	rs864745	23128233	4.00E-09	NA	1.09	[1.05-1.12]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs864745-T	Research Support, N.I.H., Extramural	Meta-Analysis
7	31786849	rs7795363	T	C	rs7795363	17684544	6.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
7	34775544	rs1419790	G	T	rs1419790	17684544	7.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
7	41872709	rs10486725	C	T	rs10486725	17684544	6.80E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
7	50269672	rs1456893	G	A	rs1456893	18587394	5.00E-09	NA	1.2	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1456893-A	Research Support, N.I.H., Extramural	Meta-Analysis
7	50304461	rs1456896	C	T	rs1456896	18587394	1.39E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
7	50304461	rs1456896	C	T	rs1456896	21102463	1.00E-08	NA	1.14	[1.09-1.20]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1456896-T	Research Support, N.I.H., Extramural	Meta-Analysis
7	80279718	rs3211830	C	T	rs3211830	17684544	3.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
7	81839553	rs11978472	A	C	rs11978472	23665963	6.00E-06	NA	2	[1.43-2.50]	239 European ancestry cases that required surgery within 5 year; 375 European ancestry cases that did not require surgery within 5 years	European(614)	ALL(614)	EUR(614)	ALL(614)	Crohn's disease (need for surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	88295001	rs12531232	T	C	rs12531232	23665963	4.30E-05	NA	1.6	NA	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs12531232-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	98887802	rs10953286	C	T	rs10953286	20570966	4.40E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	102471213	rs10487283	T	C	rs10487283	17684544	8.60E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
7	109782499	rs1722052	T	G	rs1722052	23665963	4.10E-05	NA	1.67	NA	239 European ancestry cases that required surgery within 5 year; 375 European ancestry cases that did not require surgery within 5 years	European(614)	ALL(614)	EUR(614)	ALL(614)	Crohn's disease (need for surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
7	110442772	rs1528039	A	G	rs1528039	17684544	9.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
7	112718186	rs2255323	C	T	rs2255323	22482804	8.86E-09	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
7	113707787	rs10500037	T	C	rs10500037	17684544	9.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
7	114357543	rs1869839	A	G	rs1869839	22936669	7.00E-06	NA	1.2	[1.11-1.30]	1,277 European ancestry cases; 1,488 European ancestry controls	European(2765)	ALL(2765)	EUR(2765)	ALL(2765)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
7	118515456	rs10500069	A	G	rs10500069	17684544	8.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
7	125533006	rs6947579	G	C	rs6947579	17684544	4.80E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
7	125570097	rs10487428	A	T	rs10487428	17684544	5.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
7	148258048	rs7807268	G	C	rs7807268	17554300	4.00E-06	NA	1.38	[1.20-1.60]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7807268-G	Multicenter Study	Research Support, N.I.H., Extramural
7	154402669	rs1488927	C	G	rs1488927	17684544	6.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
8	4638706	rs10503282	A	G	rs10503282	17684544	3.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
8	15013234	rs10503536	A	G	rs10503536	17684544	9.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
8	17670196	rs396462	G	C	rs396462	17684544	6.90E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
8	52820274	rs11775611	T	C	rs11775611	17804789	4.07E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
8	59217726	rs10504252	A	C	rs10504252	17684544	7.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
8	74007347	rs12677663	G	T	rs12677663	22412388	2.00E-08	NA	1.15	[1.04-1.28]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs12677663-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
8	78500065	rs723510	T	C	rs723510	17684544	6.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
8	90875918	rs7015630	T	C	rs7015630	23128233	1.00E-08	NA	1.08	[1.03-1.12]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7015630-T	Research Support, N.I.H., Extramural	Meta-Analysis
8	101975479	rs2386922	T	G	rs2386922	17804789	2.04E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
8	102330393	rs10505007	A	G	rs10505007	17435756	3.78E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
8	106707739	rs6469010	T	C	rs6469010	23665963	1.90E-05	NA	1.8	[1.40-2.40]	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs6469010-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
8	114799224	rs2044999	G	A	rs2044999	17435756	3.84E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
8	117928825	rs3020167	C	T	rs3020167	23850713	5.82E-05	NA	1.2	[1.10-1.31]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3020167-T	Research Support, Non-U.S. Gov't	Validation Studies
8	126534671	rs921720	A	G	rs921720	18587394	2.78E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
8	126537570	rs4871611	G	A	rs4871611	21102463	2.00E-12	NA	1.17	[1.12-1.23]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4871611-A	Research Support, N.I.H., Extramural	Meta-Analysis
8	126540051	rs1551398	G	A	rs1551398	18587394	5.00E-09	NA	1.08	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1551398-A	Research Support, N.I.H., Extramural	Meta-Analysis
8	127092882	rs1906493	G	T	rs1906493	22412388	3.00E-06	NA	1.19	[1.09-1.28]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1906493-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
8	129567181	rs6651252	T	C	rs6651252	21102463	4.00E-18	NA	1.23	[1.17-1.30]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6651252-T	Research Support, N.I.H., Extramural	Meta-Analysis
8	129567181	rs6651252	T	C	rs6651252	23128233	1.00E-16	NA	1.19	[1.13-1.25]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6651252-T	Research Support, N.I.H., Extramural	Meta-Analysis
8	138378521	rs10505673	C	T	rs10505673	17684544	4.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C,T
9	4974441	rs1327495	G	A	rs1327495	23266558	8.59E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	4979730	rs1887427	A	G	rs1887427	23266558	6.43E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	4981602	rs10758669	C	A	rs10758669	18587394	3.00E-09	NA	1.12	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10758669-C	Research Support, N.I.H., Extramural	Meta-Analysis
9	4981602	rs10758669	C	A	rs10758669	21102463	1.00E-13	NA	1.18	[1.13-1.23]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10758669-C	Research Support, N.I.H., Extramural	Meta-Analysis
9	4985879	rs2274471	A	G	rs2274471	23266558	5.00E-06	NA	1.27	[1.15-1.41]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2274471-A	Research Support, Non-U.S. Gov't	Comparative Study
9	4988761	rs7849191	C	T	rs7849191	18587394	4.34E-08	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
9	19458939	rs960908	C	T	rs960908	20570966	6.50E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	27201968	rs1413829	A	G	rs1413829	17684544	6.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
9	29223296	rs10813028	C	T	rs10813028	20570966	4.16E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	86707888	rs7029403	G	A	rs7029403	23665963	3.30E-05	NA	2	[1.43-2.50]	239 European ancestry cases that required surgery within 5 year; 375 European ancestry cases that did not require surgery within 5 years	European(614)	ALL(614)	EUR(614)	ALL(614)	Crohn's disease (need for surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	89959601	rs4878061	G	A	rs4878061	17435756	4.64E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
9	93008041	rs10821091	C	T	rs10821091	17435756	1.44E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
9	104479480	rs4743484	C	T	rs4743484	17684544	8.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	104536303	rs4743487	A	C	rs4743487	17684544	2.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
9	109819928	rs4978664	G	A	rs4978664	17684544	1.67E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
9	115698346	rs747066	C	T	rs747066	17684544	1.50E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	117420132	rs2274598	A	G	rs2274598	16221758	8.50E-05	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
9	117444370	rs1075371	C	A	rs1075371	16221758	1.45E-04	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	117483015	rs10817669	G	A	rs10817669	23266558	2.96E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117504798	rs2068955	A	G	rs2068955	23266558	2.72E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117516418	rs7038398	C	A	rs7038398	23266558	2.80E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117521582	rs12552933	C	T	rs12552933	23266558	3.76E-08	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117530319	rs4978609	A	G	rs4978609	23266558	3.34E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117538334	rs4574921	C	T	rs4574921	16221758	7.76E-11	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
9	117538334	rs4574921	C	T	rs4574921	23266558	1.83E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117545666	rs6478106	C	T	rs6478106	16221758	7.76E-07	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	117545666	rs6478106	C	T	rs6478106	23266558	5.00E-46	NA	1.73	[1.60-1.86]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6478106-T	Research Support, Non-U.S. Gov't	Comparative Study
9	117547772	rs10114470	T	C	rs10114470	23266558	4.82E-11	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117551603	rs10117785	T	A	rs10117785	16221758	2.51E-12	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
9	117552885	rs3810936	T	C	rs3810936	16221758	3.89E-11	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	117552885	rs3810936	T	C	rs3810936	21102463	1.00E-15	NA	1.21	[1.15-1.27]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3810936-C	Research Support, N.I.H., Extramural	Meta-Analysis
9	117553249	rs4246905	T	C	rs4246905	16221758	3.02E-06	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
9	117558703	rs6478108	C	T	rs6478108	16221758	5.62E-14	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
9	117558703	rs6478108	C	T	rs6478108	23266558	1.53E-12	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117563687	rs4372078	T	G	rs4372078	16221758	6.46E-10	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
9	117566440	rs4263839	A	G	rs4263839	18587394	3.00E-10	NA	1.22	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4263839-G	Research Support, N.I.H., Extramural	Meta-Analysis
9	117567013	rs4979462	C	T	rs4979462	16221758	3.38E-13	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	117568766	rs6478109	A	G	rs6478109	16221758	1.17E-11	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
9	117568766	rs6478109	A	G	rs6478109	18587394	3.67E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
9	117568766	rs6478109	A	G	rs6478109	23266558	6.84E-12	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117569046	rs7848647	T	C	rs7848647	16221758	4.43E-11	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	117580914	rs7869487	C	T	rs7869487	16221758	3.24E-11	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
9	117592638	rs2006996	T	C	rs2006996	23266558	1.22E-10	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117618309	rs16931910	A	C	rs16931910	16221758	5.50E-08	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
9	117627569	rs7866342	G	T	rs7866342	23266558	2.69E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117630043	rs4979467	C	T	rs4979467	23266558	6.72E-09	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117642418	rs7863183	T	C	rs7863183	23266558	1.33E-07	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117645015	rs7028891	A	G	rs7028891	23266558	1.30E-06	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117664172	rs2974	T	C	rs2974	16221758	1.97E-07	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	117664211	rs2295800	T	C	rs2295800	16221758	3.06E-08	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
9	117664211	rs2295800	T	C	rs2295800	23266558	1.79E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117667443	rs3181362	T	C	rs3181362	16221758	2.75E-04	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
9	117667443	rs3181362	T	C	rs3181362	23266558	6.38E-10	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117667937	rs3181196	G	A,C,T	rs3181196	16221758	2.75E-06	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	117669270	rs3827818	C	T	rs3827818	16221758	5.62E-05	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
9	117669299	rs1322054	A	G	rs1322054	16221758	9.13E-09	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
9	117669699	rs3789882	A	T	rs3789882	16221758	4.45E-09	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
9	117678236	rs3789879	T	C	rs3789879	16221758	3.70E-09	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
9	117679802	rs1885383	G	A	rs1885383	16221758	1.61E-09	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
9	117690864	rs2181032	C	T	rs2181032	16221758	4.37E-05	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	117691364	rs4978612	T	A	rs4978612	16221758	5.50E-05	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
9	117691558	rs3181360	C	A,G,T	rs3181360	16221758	8.13E-05	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
9	117691558	rs3181360	C	A,G,T	rs3181360	23266558	7.94E-10	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117692344	rs3181357	G	A	rs3181357	16221758	2.88E-06	Crohn's disease	NA	NA	94 Japanese CD patients; 752 Japanese controls	Japanese(846)	ALL(846)	ASN(846)	ALL(846)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
9	117694184	rs3181348	G	A	rs3181348	23266558	2.33E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117754106	rs16932027	C	T	rs16932027	23266558	3.77E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	117757075	rs17817825	A	C	rs17817825	23266558	5.34E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
9	135974100	rs886017	G	A	rs886017	22482804	1.43E-05	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
9	137506578	rs11103429	A	G	rs11103429	23665963	6.00E-06	NA	3.6	[2.10-6.30]	239 European ancestry cases that required surgery within 5 year; 375 European ancestry cases that did not require surgery within 5 years	European(614)	ALL(614)	EUR(614)	ALL(614)	Crohn's disease (need for surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs11103429-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
9	139266496	rs4077515	C	T	rs4077515	21102463	1.00E-36	NA	1.18	[1.13-1.22]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4077515-T	Research Support, N.I.H., Extramural	Meta-Analysis
9	139266496	rs4077515	C	T	rs4077515	22936669	4.00E-06	NA	1.29	NA	1,277 European ancestry cases; 1,488 European ancestry controls	European(2765)	ALL(2765)	EUR(2765)	ALL(2765)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4077515-T	Research Support, Non-U.S. Gov't	G
9	139396113	rs11574906	T	A	rs11574906	22482804	2.74E-07	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
10	3862542	rs6601764	C	T	rs6601764	17554300	9.00E-06	NA	1.16	[1.01-1.33]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs6601764-C	Multicenter Study	Research Support, N.I.H., Extramural
10	6102012	rs12722489	C	T	rs12722489	21102463	3.00E-09	NA	1.11	[1.05-1.16]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs12722489-C	Research Support, N.I.H., Extramural	Meta-Analysis
10	13659738	rs2478126	A	C	rs2478126	17684544	2.70E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
10	15821778	rs10508494	C	G	rs10508494	17684544	8.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
10	20646439	rs10508621	C	G	rs10508621	17684544	8.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
10	23665438	rs1398024	G	T	rs1398024	18723019	4.00E-06	NA	1.23	[1.04-1.45]	382 CD cases; 398 SA cases; 394 controls	NOPOP(1174)	ALL(1174)	NOPOP(1174)	ALL(1174)	Crohn's disease and sarcoidosis (combined)	HPOID:0100280	Crohn's disease	DOID:8778	DOID:13402	Crohn's disease	skin sarcoidosis	D003424	Crohn Disease	NA	NA	Enteritis	Intestinal disease	Sarcoidosis
10	35287650	rs17582416	T	G	rs17582416	18587394	2.00E-09	NA	1.16	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs17582416-G	Research Support, N.I.H., Extramural	Meta-Analysis
10	35535695	rs12242110	A	G	rs12242110	21102463	1.00E-09	NA	1.15	[1.10-1.20]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs12242110-G	Research Support, N.I.H., Extramural	Meta-Analysis
10	35549257	rs3936503	G	A	rs3936503	18587394	8.04E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
10	50294670	rs4317904	G	A	rs4317904	21298027	2.80E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
10	52010708	rs10508921	C	T	rs10508921	17684544	4.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
10	59913151	rs1819658	C	T	rs1819658	21102463	9.00E-17	NA	1.19	[1.13-1.25]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1819658-C	Research Support, N.I.H., Extramural	Meta-Analysis
10	61713218	rs7094419	T	C	rs7094419	23266558	1.82E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
10	64414060	rs7071642	G	A	rs7071642	22482804	3.41E-08	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
10	64415184	rs7076156	A	G	rs7076156	22412388	7.00E-09	NA	1.19	[1.10-1.30]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7076156-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
10	64438486	rs10995271	G	C	rs10995271	18587394	4.00E-20	NA	1.25	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10995271-C	Research Support, N.I.H., Extramural	Meta-Analysis
10	64445564	rs10761659	A	G	rs10761659	17554300	2.00E-06	NA	1.23	[1.05-1.45]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10761659-G	Multicenter Study	Research Support, N.I.H., Extramural
10	64445564	rs10761659	A	G	rs10761659	21102463	4.00E-22	NA	1.23	[1.18-1.29]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10761659-G	Research Support, N.I.H., Extramural	Meta-Analysis
10	64445564	rs10761659	A	G	rs10761659	22936669	5.00E-06	NA	1.28	NA	1,277 European ancestry cases; 1,488 European ancestry controls	European(2765)	ALL(2765)	EUR(2765)	ALL(2765)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10761659-G	Research Support, Non-U.S. Gov't	A
10	64466802	rs224135	A	G	rs224135	23266558	2.84E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
10	64470675	rs224136	C	T	rs224136	17435756	1.00E-10	NA	1.67	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
10	75632760	rs2675671	C	T	rs2675671	22482804	3.89E-06	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
10	75654931	rs2688610	G	A	rs2688610	18587394	3.32E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
10	76617479	rs951308	T	C	rs951308	17684544	6.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
10	76670311	rs7092435	G	C	rs7092435	17684544	1.90E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
10	77029174	rs10509357	A	G	rs10509357	17684544	1.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
10	81032885	rs1250544	G	A	rs1250544	22482804	7.00E-14	same-effect analysis	1.16	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
10	81060317	rs1250550	C	A	rs1250550	21102463	1.00E-30	NA	1.19	[1.15-1.23]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1250550-G	Research Support, N.I.H., Extramural	Meta-Analysis
10	91414563	rs78765440	T	C	rs78765440	23266558	5.40E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
10	98988469	rs793515	A	C	rs793515	17684544	2.50E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
10	100383999	rs483952	C	G,T	rs483952	17684544	8.73E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
10	101284237	rs4409764	T	G	rs4409764	21102463	2.00E-20	NA	1.22	[1.17-1.27]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4409764-T	Research Support, N.I.H., Extramural	Meta-Analysis
10	101287764	rs10883365	G	A	rs10883365	17554261	4.00E-10	NA	1.18	[1.05-1.32]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
10	101287764	rs10883365	G	A	rs10883365	17554300	6.00E-08	NA	1.2	[1.03-1.39]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10883365-G	Multicenter Study	Research Support, N.I.H., Extramural
10	101291593	rs11190140	T	C	rs11190140	18587394	3.00E-16	NA	1.2	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11190140-T	Research Support, N.I.H., Extramural	Meta-Analysis
10	101292390	rs11190141	C	T	rs11190141	22412388	5.00E-07	NA	1.34	[1.25-1.43]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11190141-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
10	108332996	rs12415344	G	A	rs12415344	22482804	9.38E-05	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
10	112186148	rs11195128	C	T	rs11195128	23850713	2.00E-10	NA	1.42	[1.28-1.58]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11195128-T	Research Support, Non-U.S. Gov't	Validation Studies
10	117350004	rs10509992	A	G	rs10509992	17684544	8.67E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
10	117350297	rs2804200	C	G	rs2804200	17684544	2.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
10	117350560	rs10509991	A	G	rs10509991	17684544	3.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
10	117358809	rs1590736	A	G	rs1590736	17684544	1.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
10	117358919	rs1590734	G	C	rs1590734	17684544	5.57E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
10	121105311	rs10886462	A	G	rs10886462	17804789	9.55E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
10	121859814	rs1467785	T	C	rs1467785	20570966	8.56E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
10	133172119	rs10734105	G	A	rs10734105	22412388	3.00E-08	NA	1.27	[1.10-1.43]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs10734105-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
10	133231622	rs3922590	C	T	rs3922590	17684544	5.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
11	14070567	rs1919295	C	T	rs1919295	20570966	5.26E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	20698929	rs1793004	C	G	rs1793004	17684544	3.00E-06	NA	1.3	[1.12-1.52]	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
11	20700775	rs951199	C	G	rs951199	17684544	8.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
11	20876346	rs12293297	G	A	rs12293297	17684544	9.50E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
11	35364435	rs3847621	G	A	rs3847621	17684544	9.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A,G
11	35998208	rs10836477	T	G	rs10836477	22482804	4.12E-06	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
11	42996387	rs10501292	A	G	rs10501292	17684544	8.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
11	57203009	rs11229030	C	T	rs11229030	22412388	8.00E-09	NA	1.15	[1.10-1.39]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11229030-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	61557803	rs102275	T	C	rs102275	21102463	2.00E-11	NA	1.08	[1.04-1.12]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs102275-C	Research Support, N.I.H., Extramural	Meta-Analysis
11	64097233	rs694739	A	G	rs694739	21102463	6.00E-10	NA	1.1	[1.05-1.16]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs694739-A	Research Support, N.I.H., Extramural	Meta-Analysis
11	64150370	rs559928	T	C	rs559928	18587394	7.44E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
11	64210652	rs596308	G	A	rs596308	18587394	3.45E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
11	72184591	rs11235508	C	T	rs11235508	23665963	1.50E-05	NA	2.2	NA	239 European ancestry cases that required surgery within 5 year; 375 European ancestry cases that did not require surgery within 5 years	European(614)	ALL(614)	EUR(614)	ALL(614)	Crohn's disease (need for surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs11235508-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	72184591	rs11235508	C	T	rs11235508	23665963	2.50E-05	NA	1.9	[1.40-2.50]	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs11235508-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	72533536	rs11235604	C	T	rs11235604	23850713	2.44E-12	NA	1.61	[1.41-1.83]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11235604-T	Research Support, Non-U.S. Gov't	Validation Studies
11	72670900	rs72981516	T	G	rs72981516	23266558	4.00E-07	NA	1.28	[1.27-1.29]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs72981516-T	Research Support, Non-U.S. Gov't	Comparative Study
11	72863697	rs11235667	A	G	rs11235667	23850713	7.00E-09	NA	1.46	[1.28-1.65]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11235667-G	Research Support, Non-U.S. Gov't	Validation Studies
11	74852100	rs2712800	T	G	rs2712800	17435756	2.38E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
11	76301316	rs7927894	C	T	rs7927894	18587394	1.00E-09	NA	1.16	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7927894-T	Research Support, N.I.H., Extramural	Meta-Analysis
11	76301375	rs7927997	C	T	rs7927997	21102463	6.00E-13	NA	1.17	[1.12-1.22]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7927997-T	Research Support, N.I.H., Extramural	Meta-Analysis
11	76339953	rs11236811	G	A	rs11236811	23266558	7.61E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
11	76975467	rs1793483	T	C	rs1793483	17684544	4.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
11	88638182	rs549700	C	T	rs549700	17684544	7.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
11	90262683	rs10501720	A	T	rs10501720	17684544	2.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
11	92865007	rs12576495	T	C	rs12576495	17804789	1.00E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
11	95840120	rs10501843	G	A	rs10501843	17684544	1.80E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
11	95840436	rs1074742	A	G	rs1074742	17684544	1.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
11	114093055	rs3781990	C	T	rs3781990	20570966	7.80E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
11	114999873	rs2513676	A	G	rs2513676	20570966	2.30E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	2481936	rs886898	T	C	rs886898	17435756	1.93E-05	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
12	21014139	rs3764008	C	G	rs3764008	17684544	3.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
12	21014163	rs3764007	T	A	rs3764007	17684544	5.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
12	28491157	rs2169755	C	G	rs2169755	21298027	6.45E-05	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
12	28521109	rs1586868	C	T	rs1586868	21298027	7.36E-05	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
12	28534569	rs1257741	G	C	rs1257741	21298027	5.62E-05	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
12	28605426	rs10771427	G	A	rs10771427	21298027	5.72E-05	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
12	40601940	rs11175593	C	T	rs11175593	18587394	3.00E-10	NA	1.54	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11175593-T	Research Support, N.I.H., Extramural	Meta-Analysis
12	40792300	rs11564258	G	A	rs11564258	21102463	6.00E-21	NA	1.74	[1.55-1.95]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11564258-A	Research Support, N.I.H., Extramural	Meta-Analysis
12	43149010	rs11181674	A	T	rs11181674	17804789	8.71E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
12	43714537	rs2134066	A	G	rs2134066	17684544	8.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
12	46043613	rs10492248	T	C	rs10492248	17684544	9.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
12	51087857	rs10506296	C	G	rs10506296	17684544	9.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
12	56439209	rs12580100	A	G	rs12580100	22482804	6.18E-07	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
12	59773458	rs1996199	A	G	rs1996199	18587394	3.97E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
12	74874472	rs10785122	A	G	rs10785122	20570966	6.16E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	96267298	rs10507063	G	C	rs10507063	17684544	1.19E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
12	101530109	rs823559	A	G	rs823559	23665963	4.80E-05	NA	2	[1.40-2.80]	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs823559-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
12	102985749	rs1463446	A	G	rs1463446	17684544	5.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
12	124583446	rs902169	G	A	rs902169	20570966	9.90E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
13	20939236	rs1105267	G	A	rs1105267	17068223	5.12E-10	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	C
13	24318963	rs1536299	A	C	rs1536299	17684544	6.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
13	24531398	rs2765122	G	A	rs2765122	23665963	3.80E-05	NA	2	NA	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
13	36848187	rs912927	T	C	rs912927	20570966	8.20E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
13	39445743	rs9548517	G	A	rs9548517	23665963	3.00E-05	NA	1.8	[1.40-2.40]	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs9548517-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
13	41416221	rs7992208	T	C	rs7992208	23266558	1.09E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41427029	rs59597769	T	C	rs59597769	23266558	1.66E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41427506	rs77419885	C	T	rs77419885	23266558	2.00E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41437926	rs7339089	C	T	rs7339089	23266558	1.62E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41438217	rs79487860	G	A	rs79487860	23266558	2.71E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41470342	rs7329474	C	T	rs7329474	23266558	3.32E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41487686	rs57088152	T	C	rs57088152	23266558	1.75E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41501643	rs9594460	C	A	rs9594460	23266558	3.32E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41510339	rs77419017	G	A	rs77419017	23266558	1.39E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41522272	rs75719223	T	G	rs75719223	23266558	1.51E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41526350	rs60129138	C	T	rs60129138	23266558	1.96E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41539817	rs17630801	A	C	rs17630801	23266558	1.59E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41547143	rs77553977	T	C	rs77553977	23266558	5.93E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41552738	rs9532692	G	A	rs9532692	23266558	2.63E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41555724	rs78076494	G	A	rs78076494	23266558	1.48E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41557118	rs57668933	T	C	rs57668933	23266558	2.75E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41558110	rs7329174	A	G	rs7329174	23266558	8.00E-09	NA	1.27	[1.17-1.38]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs7329174-G	Research Support, Non-U.S. Gov't	Comparative Study
13	41562860	rs12585650	C	A	rs12585650	23266558	1.56E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41563902	rs78053745	T	C	rs78053745	23266558	2.86E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41564287	rs59691646	A	C	rs59691646	23266558	2.53E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41568872	rs80022860	G	A	rs80022860	23266558	2.17E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41575804	rs74674762	T	C	rs74674762	23266558	2.86E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41579868	rs7335629	T	C	rs7335629	23266558	8.39E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41583941	rs12584853	C	T	rs12584853	23266558	6.96E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41585055	rs74757048	T	C	rs74757048	23266558	1.81E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41588832	rs4264266	G	T	rs4264266	23266558	1.03E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	41602462	rs61300271	T	C	rs61300271	23266558	4.81E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
13	43052880	rs2062305	G	A	rs2062305	21102463	5.00E-10	NA	1.1	[1.05-1.15]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2062305-G	Research Support, N.I.H., Extramural	Meta-Analysis
13	44457925	rs3764147	A	G	rs3764147	18587394	2.00E-13	NA	1.25	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3764147-G	Research Support, N.I.H., Extramural	Meta-Analysis
13	44457925	rs3764147	A	G	rs3764147	21102463	1.00E-10	NA	1.17	[1.12-1.23]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3764147-G	Research Support, N.I.H., Extramural	Meta-Analysis
13	44457925	rs3764147	A	G	rs3764147	23128233	2.00E-21	NA	1.16	[1.11-1.20]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3764147-G	Research Support, N.I.H., Extramural	Meta-Analysis
13	44599789	rs9562532	G	A	rs9562532	18587394	1.44E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
13	59844496	rs1998828	G	T	rs1998828	23665963	2.70E-05	NA	1.6	NA	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs1998828-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
13	61188132	rs995085	C	T	rs995085	20570966	8.00E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
13	66536090	rs17837226	C	T	rs17837226	17804789	4.37E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
13	69763228	rs8000906	C	T	rs8000906	17684544	5.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
13	75331093	rs11617463	C	A	rs11617463	17435756	1.62E-05	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
13	79744855	rs605216	G	T	rs605216	17684544	2.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
13	94906103	rs1333261	C	T	rs1333261	17684544	1.80E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
13	96234753	rs7324781	C	T	rs7324781	17684544	4.37E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
14	25616536	rs9323605	G	A	rs9323605	17684544	8.10E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
14	32728233	rs6571501	C	A	rs6571501	20570966	7.46E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
14	33591105	rs8005131	G	C	rs8005131	17684544	4.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
14	38185661	rs4901140	A	G	rs4901140	23665963	1.90E-05	NA	1.7	[1.40-2.30]	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs4901140-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
14	52413573	rs10498440	T	C	rs10498440	17684544	2.50E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
14	56454074	rs1188157	C	T	rs1188157	17435756	1.58E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
14	69210199	rs4902642	G	A	rs4902642	21102463	2.00E-10	NA	1.07	[1.11-1.04]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4902642-G	Research Support, N.I.H., Extramural	Meta-Analysis
14	76001394	rs7161377	T	C	rs7161377	18587394	2.25E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
14	76031313	rs7159570	A	G	rs7159570	23665963	1.80E-05	NA	2	[1.11-2.50]	239 European ancestry cases that required surgery within 5 year; 375 European ancestry cases that did not require surgery within 5 years	European(614)	ALL(614)	EUR(614)	ALL(614)	Crohn's disease (need for surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
14	88472595	rs8005161	C	T	rs8005161	21102463	4.00E-18	NA	1.23	[1.16-1.31]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs8005161-T	Research Support, N.I.H., Extramural	Meta-Analysis
14	97857732	rs8011773	C	T	rs8011773	17684544	5.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
14	99375321	rs200354	G	T	rs200354	17684544	2.22E-06	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
14	101539131	rs2295655	G	A	rs2295655	23665963	3.60E-05	NA	1.8	[1.30-2.30]	239 European ancestry cases that required surgery within 5 year; 375 European ancestry cases that did not require surgery within 5 years	European(614)	ALL(614)	EUR(614)	ALL(614)	Crohn's disease (need for surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs2295655-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	24050205	rs10519449	T	C	rs10519449	17684544	8.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
15	38899190	rs16967103	T	C	rs16967103	23128233	4.00E-09	NA	1.09	[1.04-1.13]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs16967103-C	Research Support, N.I.H., Extramural	Meta-Analysis
15	40558087	rs2016902	G	A	rs2016902	22482804	1.42E-06	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
15	56701500	rs2414476	C	A	rs2414476	17804789	8.71E-09	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
15	67442596	rs17293632	C	T	rs17293632	21102463	3.00E-19	NA	1.12	[1.07-1.16]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs17293632-T	Research Support, N.I.H., Extramural	Meta-Analysis
15	85581389	rs289386	C	T	rs289386	17684544	6.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
15	86268672	rs471073	C	A	rs471073	23665963	1.70E-05	NA	1.8	[1.40-2.30]	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs471073-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	86360145	rs4842903	C	A	rs4842903	20570966	9.96E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
15	92720600	rs10520704	A	G	rs10520704	17684544	8.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
15	95927728	rs10520778	C	A	rs10520778	17684544	9.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	3203335	rs224188	T	C	rs224188	17447842	2.00E-04	NA	NA	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	11347858	rs4780355	T	C	rs4780355	22482804	1.00E-13	same-effect analysis	1.16	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
16	17912586	rs1994893	T	C	rs1994893	17684544	9.20E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	28490517	rs151181	T	C	rs151181	21102463	2.00E-11	NA	1.07	[1.03-1.12]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs151181-G	Research Support, N.I.H., Extramural	Meta-Analysis
16	50443200	rs4369662	T	C	rs4369662	17804789	4.90E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50445412	rs4483840	G	T	rs4483840	17804789	4.70E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	50464110	rs1861543	C	T	rs1861543	17804789	5.11E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50508101	rs6500315	A	G	rs6500315	17804789	1.04E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50525105	rs1592473	T	G	rs1592473	17804789	3.85E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50536826	rs12149258	A	G	rs12149258	17804789	7.73E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50565970	rs1990623	A	G	rs1990623	17804789	3.16E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	50627378	rs4785220	T	C	rs4785220	17804789	2.31E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50660764	rs8046845	G	A	rs8046845	17804789	4.33E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50662844	rs1558663	G	A	rs1558663	17804789	1.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50665089	rs11640716	T	G	rs11640716	17804789	4.97E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	50666566	rs7198686	T	C	rs7198686	17804789	7.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50668426	rs12913	T	C	rs12913	17804789	4.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50670182	rs745230	G	C	rs745230	17804789	4.30E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50671721	rs12924696	G	A	rs12924696	17804789	1.97E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50673651	rs749985	T	C	rs749985	17804789	1.42E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50679315	rs9926095	A	C	rs9926095	17804789	6.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50686557	rs7186163	A	C	rs7186163	17804789	3.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50687673	rs8050932	C	T	rs8050932	17804789	1.58E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50692364	rs1109863	G	A	rs1109863	17804789	3.16E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50709723	rs6596	G	A	rs6596	17804789	4.71E-29	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50714029	rs7202124	G	A	rs7202124	17804789	2.38E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50715185	rs2066848	G	A	rs2066848	17804789	1.51E-09	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50718041	rs8062727	G	A	rs8062727	17804789	7.67E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50719674	rs1420685	T	C	rs1420685	17804789	7.05E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50720917	rs2004804	G	A	rs2004804	17804789	5.11E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50723074	rs1981760	C	T	rs1981760	17804789	6.12E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50725193	rs7194886	C	T	rs7194886	17804789	2.93E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50730446	rs4785224	G	A	rs4785224	17804789	1.01E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50733374	rs2076753	G	T	rs2076753	17804789	8.63E-23	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50733969	rs2111235	A	G	rs2111235	17804789	4.16E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50737980	rs8057341	A	G	rs8057341	17804789	2.14E-09	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50739582	rs17221417	C	G	rs17221417	17554300	4.00E-11	NA	1.29	[1.13-1.46]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs17221417-G	Multicenter Study	Research Support, N.I.H., Extramural
16	50739582	rs17221417	C	G	rs17221417	17804789	4.11E-25	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50741462	rs17312836	A	C	rs17312836	17804789	4.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50743331	rs11647841	G	A	rs11647841	17804789	1.55E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50744624	rs2066842	C	T	rs2066842	17804789	3.49E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50745199	rs2066843	C	T	rs2066843	17068223	2.86E-09	NA	NA	NA	547 cases; 548 controls	NOPOP(1095)	ALL(1095)	NOPOP(1095)	ALL(1095)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	C
16	50745926	rs2066844	C	T	rs2066844	17684544	1.29E-18	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50745926	rs2066844	C	T	rs2066844	17804789	2.61E-10	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50747704	rs17313265	C	T	rs17313265	17804789	7.31E-29	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50751175	rs751271	T	G	rs751271	17804789	5.26E-11	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50753424	rs7203691	G	A	rs7203691	17804789	1.37E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50755709	rs10521209	T	G	rs10521209	17684544	8.65E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	50756540	rs2066845	G	C,T	rs2066845	17684544	7.44E-10	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50756540	rs2066845	G	C,T	rs2066845	17804789	1.00E-45	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50756540	rs2066845	G	C,T	rs2066845	18587394	4.62E-08	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
16	50756774	rs5743289	C	G,T	rs5743289	17447842	1.00E-06	NA	NA	NA	547 cases; 928 controls	NOPOP(1475)	ALL(1475)	NOPOP(1475)	ALL(1475)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	50756774	rs5743289	C	G,T	rs5743289	17804789	6.00E-17	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	50756881	rs2076756	A	G	rs2076756	17435756	7.00E-14	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
16	50756881	rs2076756	A	G	rs2076756	17684544	1.00E-21	NA	1.71	[1.42-2.05]	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50756881	rs2076756	A	G	rs2076756	17804789	1.00E-09	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50756881	rs2076756	A	G	rs2076756	21102463	4.00E-69	NA	1.53	[1.46-1.60]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2076756-G	Research Support, N.I.H., Extramural	Meta-Analysis
16	50756881	rs2076756	A	G	rs2076756	22412388	1.00E-37	NA	1.66	[1.48-1.88]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2076756-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
16	50756881	rs2076756	A	G	rs2076756	22936669	3.00E-10	NA	1.46	NA	1,277 European ancestry cases; 1,488 European ancestry controls	European(2765)	ALL(2765)	EUR(2765)	ALL(2765)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2076756-G	Research Support, Non-U.S. Gov't	A
16	50757276	rs5743291	G	A	rs5743291	17804789	1.00E-20	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50758849	rs749910	G	A	rs749910	17804789	1.84E-31	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50763778	rs199883290	G	C	rs2066847	17684544	2.51E-49	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50763778	rs199883290	G	C	rs2066847	18587394	3.00E-24	NA	3.99	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2066847-C	Research Support, N.I.H., Extramural	Meta-Analysis
16	50763778	rs199883290	G	C	rs2066847	20570966	2.00E-15	NA	1.62	[1.42-1.86]	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
16	50763778	rs199883290	G	C	rs2066847	23128233	6.00E-209	NA	3.1	[1.50-1.62]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2066847-T	Research Support, N.I.H., Extramural	Meta-Analysis
16	50763778	rs2066847	G	GC	rs2066847	17684544	2.51E-49	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50763778	rs2066847	G	GC	rs2066847	18587394	3.00E-24	NA	3.99	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2066847-C	Research Support, N.I.H., Extramural	Meta-Analysis
16	50763778	rs2066847	G	GC	rs2066847	20570966	2.00E-15	NA	1.62	[1.42-1.86]	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
16	50763778	rs2066847	G	GC	rs2066847	23128233	6.00E-209	NA	3.1	[1.50-1.62]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2066847-T	Research Support, N.I.H., Extramural	Meta-Analysis
16	50763778	rs540973741	G	GC	rs2066847	17684544	2.51E-49	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50763778	rs540973741	G	GC	rs2066847	18587394	3.00E-24	NA	3.99	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2066847-C	Research Support, N.I.H., Extramural	Meta-Analysis
16	50763778	rs540973741	G	GC	rs2066847	20570966	2.00E-15	NA	1.62	[1.42-1.86]	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
16	50763778	rs540973741	G	GC	rs2066847	23128233	6.00E-209	NA	3.1	[1.50-1.62]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2066847-T	Research Support, N.I.H., Extramural	Meta-Analysis
16	50763778	rs5743293	G	GC	rs2066847	17684544	2.51E-49	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50763778	rs5743293	G	GC	rs2066847	18587394	3.00E-24	NA	3.99	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2066847-C	Research Support, N.I.H., Extramural	Meta-Analysis
16	50763778	rs5743293	G	GC	rs2066847	20570966	2.00E-15	NA	1.62	[1.42-1.86]	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
16	50763778	rs5743293	G	GC	rs2066847	23128233	6.00E-209	NA	3.1	[1.50-1.62]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2066847-T	Research Support, N.I.H., Extramural	Meta-Analysis
16	50766127	rs3135499	A	C	rs3135499	17804789	1.62E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50767647	rs8056611	A	G	rs8056611	17804789	6.68E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50775745	rs751919	T	G	rs751919	17804789	2.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	50781802	rs8060598	T	C	rs8060598	17804789	3.16E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	50787483	rs7342715	A	G	rs7342715	17804789	1.26E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50791250	rs3135503	T	G	rs3135503	17804789	3.16E-08	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	50808726	rs6500331	G	A	rs6500331	17804789	1.89E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50817932	rs8062540	A	G	rs8062540	17804789	9.73E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50819910	rs2111435	C	T	rs2111435	17804789	2.60E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50822964	rs4785226	A	C	rs4785226	17804789	7.50E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50827601	rs2302759	A	G	rs2302759	17804789	7.00E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50829853	rs2160683	A	T	rs2160683	17804789	2.27E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	50839648	rs1861762	T	C	rs1861762	17804789	2.27E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50842077	rs4785452	T	C	rs4785452	17804789	1.79E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50848973	rs12922698	C	T	rs12922698	17804789	4.26E-09	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50916464	rs2029923	C	A	rs2029923	17804789	3.63E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50949161	rs17226979	A	G	rs17226979	17804789	6.18E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50973078	rs9935378	C	T	rs9935378	17804789	1.18E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50974725	rs4785482	C	T	rs4785482	17804789	1.09E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50976307	rs17325379	A	T	rs17325379	17804789	2.13E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
16	50978048	rs1872679	T	G	rs1872679	17804789	8.49E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50979745	rs4785483	G	C	rs4785483	17804789	9.86E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	50984731	rs6500350	C	G	rs6500350	17804789	3.66E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50988142	rs4785484	G	C	rs4785484	17804789	2.02E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50990540	rs2129247	C	T	rs2129247	17804789	3.44E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	50999201	rs1528602	T	C	rs1528602	17804789	1.82E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	51007618	rs2129250	G	A	rs2129250	17804789	5.70E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
16	51009198	rs16949179	T	C	rs16949179	17804789	7.36E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
16	51068059	rs7191446	A	G	rs7191446	17804789	5.78E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	51083636	rs8060595	A	G	rs8060595	17804789	2.13E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
16	53253710	rs58474046	T	C	rs58474046	23850713	2.84E-04	NA	1.19	[1.08-1.31]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs58474046-C	Research Support, Non-U.S. Gov't	Validation Studies
16	67971380	rs11574514	C	T	rs11574514	22412388	2.00E-07	NA	1.44	[1.35-1.52]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11574514-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
16	75167579	rs7195303	G	A	rs7195303	23665963	9.00E-06	NA	2.1	[1.50-2.80]	983 European ancestry cases	European(983)	ALL(983)	EUR(983)	ALL(983)	Crohn's disease (time to surgery)	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	NA	NA	NA	NA	Enteritis	Intestinal disease	rs7195303-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
16	84248757	rs40254	A	G	rs40254	21298027	2.97E-05	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
16	85139173	rs8050910	G	T	rs8050910	17435756	9.55E-06	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
16	85987998	rs10863202	A	G	rs10863202	18587394	1.40E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
17	25843643	rs2945412	G	A	rs2945412	23128233	9.00E-17	NA	1.14	[1.10-1.18]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2945412-A	Research Support, N.I.H., Extramural	Meta-Analysis
17	25870542	rs2948529	C	T	rs2948529	17804789	6.57E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
17	25872185	rs2948527	T	C	rs2948527	17804789	5.85E-04	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
17	25983153	rs4794986	G	A	rs4794986	17804789	6.92E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A,G
17	26103034	rs4796052	C	T	rs4796052	17804789	7.34E-04	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
17	26545488	rs12452097	C	A	rs12452097	17804789	1.10E-04	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
17	26549716	rs4435306	T	G	rs4435306	17804789	5.15E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
17	32587725	rs991804	C	T	rs991804	18587394	5.34E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
17	32593665	rs3091315	A	G	rs3091315	21102463	2.00E-13	NA	1.2	[1.14-1.26]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3091315-A	Research Support, N.I.H., Extramural	Meta-Analysis
17	32593974	rs3091316	G	A	rs3091316	22412388	4.00E-08	NA	1.14	[1.03-1.27]	737 Ashkenazi Jewish cases; 2,257 Ashkenazi Jewish controls	Ashkenazi Jewish(2994)	ALL(2994)	MEA(2994)	ALL(2994)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs3091316-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
17	38040763	rs2872507	G	A	rs2872507	18587394	5.00E-09	NA	1.12	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2872507-A	Research Support, N.I.H., Extramural	Meta-Analysis
17	38040763	rs2872507	G	A	rs2872507	21102463	2.00E-09	NA	1.14	[1.09-1.19]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2872507-A	Research Support, N.I.H., Extramural	Meta-Analysis
17	38062196	rs2305480	G	A	rs2305480	18587394	5.45E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
17	40494902	rs8069645	A	G	rs8069645	23266558	2.49E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
17	40499533	rs6503695	T	C	rs6503695	23266558	2.49E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
17	40507980	rs9891119	A	C	rs9891119	23266558	2.00E-15	NA	1.37	[1.27-1.48]	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs9891119-A	Research Support, Non-U.S. Gov't	Comparative Study
17	40514201	rs744166	A	G	rs744166	18587394	7.00E-12	NA	1.18	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs744166-A	Research Support, N.I.H., Extramural	Meta-Analysis
17	40514201	rs744166	A	G	rs744166	23266558	1.69E-05	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
17	40552794	rs2883456	C	T	rs2883456	23266558	1.42E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
17	40566240	rs1968866	T	C	rs1968866	23266558	6.96E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
17	40570602	rs12948909	A	C	rs12948909	18587394	7.10E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
17	40570772	rs11871801	A	C	rs11871801	21102463	3.00E-08	NA	1.15	[1.10-1.21]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs11871801-A	Research Support, N.I.H., Extramural	Meta-Analysis
17	40582296	rs1905339	T	C	rs1905339	23266558	3.59E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
17	41983498	rs231480	G	A	rs231480	17804789	9.04E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
17	57943115	rs2645482	T	G	rs2645482	17804789	5.57E-04	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
17	57963537	rs1292053	A	G	rs1292053	17804789	7.11E-04	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
17	58828624	rs8077981	T	C	rs8077981	17804789	5.13E-07	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
17	59158243	rs6504016	G	A	rs6504016	17804789	3.99E-05	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
17	59245274	rs4968535	T	C	rs4968535	17684544	4.50E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
18	631435	rs10502288	G	A	rs10502288	17684544	2.50E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
18	8627595	rs9304017	A	G	rs9304017	17684544	8.40E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
18	12779947	rs2542151	G	T	rs2542151	17554261	3.00E-08		1.15	[1.00-1.32]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
18	12779947	rs2542151	G	T	rs2542151	17554300	2.00E-07	NA	1.3	[1.14-1.48]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2542151-G	Multicenter Study	Research Support, N.I.H., Extramural
18	12779947	rs2542151	G	T	rs2542151	18587394	5.00E-17	NA	1.35	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2542151-G	Research Support, N.I.H., Extramural	Meta-Analysis
18	12779947	rs2542151	G	T	rs2542151	21298027	1.19E-11	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
18	12809340	rs1893217	A	G	rs1893217	18587394	7.05E-16	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
18	12809340	rs1893217	A	G	rs1893217	21102463	1.00E-14	NA	1.25	[1.18-1.32]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1893217-G	Research Support, N.I.H., Extramural	Meta-Analysis
18	12809340	rs1893217	A	G	rs1893217	21298027	6.54E-11	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
18	12847136	rs657555	C	T	rs657555	21298027	3.02E-09	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
18	13503887	rs1559865	G	T	rs1559865	17684544	1.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
18	19673331	rs8098673	A	C	rs8098673	18587394	1.44E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
18	42800148	rs10502861	C	T	rs10502861	17684544	5.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
18	47580051	rs2852095	G	A	rs2852095	17684544	9.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
18	55903021	rs158865	C	T	rs158865	18587394	1.97E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
18	56567906	rs937815	G	T	rs937815	17435756	3.25E-05	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
18	69154730	rs10514013	A	G	rs10514013	17684544	6.30E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
19	1123378	rs4807569	A	C	rs4807569	18587394	1.06E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
19	1124031	rs2024092	G	A	rs2024092	18587394	1.80E-10	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
19	1124031	rs2024092	G	A	rs2024092	23128233	8.00E-22	NA	1.16	[1.11-1.20]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2024092-A	Research Support, N.I.H., Extramural	Meta-Analysis
19	1124835	rs740495	A	G	rs740495	21102463	8.00E-12	NA	1.16	[1.10-1.21]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs740495-G	Research Support, N.I.H., Extramural	Meta-Analysis
19	1312728	rs10405308	G	A	rs10405308	22482804	1.81E-07	NA	NA	NA	2,529 European ancestry psoriasis cases; 2,142 European ancestry Crohn's disease cases; 10,460 European ancestry controls	European(15131)	ALL(15131)	EUR(15131)	ALL(15131)	Crohn's disease and psoriasis	HPOID:0100280	Crohn's disease	DOID:8778	DOID:8893	Crohn's disease	psoriasis	D011565	Psoriasis	EFOID:0000676	crohn's disease	Psoriasis	Enteritis	Intestinal disease
19	10469975	rs12720356	A	C	rs12720356	21102463	1.00E-12	NA	1.12	[1.06-1.19]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs12720356-G	Research Support, N.I.H., Extramural	Meta-Analysis
19	18439383	rs12985909	C	T	rs12985909	18587394	7.54E-07	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
19	33757062	rs736289	T	C	rs736289	21102463	9.00E-09	NA	1.06	[1.02-1.11]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs736289-T	Research Support, N.I.H., Extramural	Meta-Analysis
19	46849806	rs4802307	G	T	rs4802307	23128233	2.00E-10	NA	1.1	[1.06-1.14]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4802307-G	Research Support, N.I.H., Extramural	Meta-Analysis
19	48719688	rs2009530	C	A	rs2009530	17684544	4.92E-06	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
19	49206172	rs516246	C	T	rs516246	23128233	1.00E-15	NA	1.11	[1.07-1.14]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs516246-T	Research Support, N.I.H., Extramural	Meta-Analysis
19	49208865	rs504963	G	A	rs504963	20570966	2.00E-08	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs504963-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
19	49214274	rs281379	G	A	rs281379	21102463	7.00E-12	NA	1.07	[1.04-1.11]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs281379-A	Research Support, N.I.H., Extramural	Meta-Analysis
19	55682046	rs3859540	C	T	rs3859540	17684544	6.18E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
20	6089513	rs6516104	C	T	rs6516104	21298027	6.19E-04	NA	NA	NA	3,230 European ancestry Crohn's disease cases; 4,829 European ancestry Crohn's disease controls; 768 European ancestry celiac disease cases; 1,422 European ancestry celiac disease controls	European(10249)	ALL(10249)	EUR(10249)	ALL(10249)	Crohn's disease and Celiac disease	HPOID:0100280	Crohn's disease	DOID:8778	DOID:10608	Crohn's disease	celiac disease	D002446	Celiac Disease	EFOID:0000384	celiac disease	Celiac disease	Enteritis	Intestinal disease
20	10692559	rs973542	G	A	rs973542	17684544	2.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
20	10692989	rs6077888	C	T	rs6077888	17684544	2.70E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
20	14706879	rs6074780	T	A	rs6074780	17684544	7.12E-05	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
20	14849853	rs10485515	G	A	rs10485515	17684544	7.80E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
20	46340506	rs4810663	C	T	rs4810663	17435756	3.45E-04	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
20	47063526	rs7263053	C	T	rs7263053	17684544	3.90E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
20	47063883	rs6122682	T	C	rs6122682	17684544	7.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
20	57917689	rs6128541	T	C	rs6128541	18587394	1.80E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
20	62327582	rs2297441	G	A	rs2297441	18587394	1.30E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
20	62349586	rs4809330	A	G	rs4809330	21102463	3.00E-15	NA	1.12	[1.06-1.18]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4809330-G	Research Support, N.I.H., Extramural	Meta-Analysis
20	62349625	rs2738758	C	G	rs2738758	18587394	2.66E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
21	16805220	rs1736135	T	C	rs1736135	18587394	7.00E-09	NA	1.18	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1736135-T	Research Support, N.I.H., Extramural	Meta-Analysis
21	16812552	rs1736020	C	A	rs1736020	18587394	3.36E-08	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
21	16812552	rs1736020	C	A	rs1736020	21102463	9.00E-12	NA	1.16	[1.11-1.21]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs1736020-C	Research Support, N.I.H., Extramural	Meta-Analysis
21	28745816	rs2167597	C	T	rs2167597	20570966	8.96E-05	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
21	30549361	rs2832238	G	T	rs2832238	17684544	7.60E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
21	34776695	rs2284553	A	G	rs2284553	23128233	2.00E-16	NA	1.12	[1.09-1.16]	Up to 12,924 European ancestry cases; up to 21,442 European ancestry controls	European(34366)	ALL(34366)	EUR(34366)	ALL(34366)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2284553-G	Research Support, N.I.H., Extramural	Meta-Analysis
21	34796886	rs2834215	A	G	rs2834215	22936669	3.00E-07	NA	1.22	[1.12-1.32]	1,277 European ancestry cases; 1,488 European ancestry controls	European(2765)	ALL(2765)	EUR(2765)	ALL(2765)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	G
21	40291740	rs2836754	T	C	rs2836754	17554261	5.00E-07		1.15	[1.03-1.28]	1,748 cases; 2,938 controls	NOPOP(4686)	ALL(4686)	NOPOP(4686)	ALL(4686)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
21	42019009	rs2837758	C	T	rs2837758	17684544	9.50E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	T
21	45611950	rs743479	C	T	rs743479	18587394	4.30E-09	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
21	45615023	rs2838519	G	A	rs2838519	21102463	2.00E-14	NA	1.18	[1.13-1.23]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2838519-G	Research Support, N.I.H., Extramural	Meta-Analysis
21	45615561	rs762421	G	A	rs762421	18587394	1.00E-09	NA	1.13	NA	3,230 European ancestry cases; 4,829 European ancestry controls	European(8059)	ALL(8059)	EUR(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs762421-G	Research Support, N.I.H., Extramural	Meta-Analysis
22	21928641	rs181359	G	A	rs181359	21102463	5.00E-16	NA	1.1	[1.06-1.15]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs181359-T	Research Support, N.I.H., Extramural	Meta-Analysis
22	21939675	rs5754217	G	T	rs5754217	18587394	6.26E-06	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
22	21956653	rs2283790	A	G	rs2283790	18587394	4.55E-05	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
22	22726968	rs10483112	C	T	rs10483112	17684544	3.90E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	NA
22	27747270	rs569626	G	A	rs569626	17684544	8.00E-04	NA	NA	NA	393 cases; 399 controls	NOPOP(792)	ALL(792)	NOPOP(792)	ALL(792)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	A
22	30388758	rs737909	T	G	rs737909	23266558	3.59E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
22	30390990	rs3788423	T	C	rs3788423	23266558	3.59E-04	NA	NA	NA	372 Japanese ancestry cases; 3,389 Japanese ancestry controls	Japanese(3761)	ALL(3761)	ASN(3761)	ALL(3761)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	Comparative Study
22	30592487	rs713875	C	G	rs713875	21102463	7.00E-12	NA	1.08	[1.04-1.13]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs713875-C	Research Support, N.I.H., Extramural	Meta-Analysis
22	37258503	rs4821544	T	C	rs4821544	17435756	1.75E-05	NA	NA	NA	946 cases; 977 controls	NOPOP(1923)	ALL(1923)	NOPOP(1923)	ALL(1923)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Comparative Study
22	37308785	rs4821558	T	C	rs4821558	23850713	4.80E-04	NA	1.16	[1.07-1.27]	532 Korean ancestry cases; 733 Korean ancestry controls	Korean(1265)	ALL(1265)	ASN(1265)	ALL(1265)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4821558-C	Research Support, Non-U.S. Gov't	Validation Studies
22	39659773	rs2413583	C	T	rs2413583	21102463	1.00E-26	NA	1.23	[1.17-1.29]	6,333 European ancestry cases; 15,056 European ancestry controls	European(21389)	ALL(21389)	EUR(21389)	ALL(21389)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs2413583-C	Research Support, N.I.H., Extramural	Meta-Analysis
22	39812986	rs6001585	C	A	rs6001585	20570966	6.00E-06	NA	NA	NA	896 European ancestry cases; 3,204 European ancestry controls	European(4100)	ALL(4100)	EUR(4100)	ALL(4100)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't
22	41431342	rs4820425	C	A,G,T	rs4820425	22936669	3.00E-08	NA	1.27	[1.17-1.38]	1,277 European ancestry cases; 1,488 European ancestry controls	European(2765)	ALL(2765)	EUR(2765)	ALL(2765)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	rs4820425-A	Research Support, Non-U.S. Gov't	C
X	34657756	rs6632039	G	T	rs6632039	17804789	6.03E-06	NA	NA	NA	382 trios	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, Non-U.S. Gov't	C
X	126902497	rs226534	A	G	rs226534	18587394	2.23E-20	NA	NA	NA	3,230 cases; 4,829 controls	NOPOP(8059)	ALL(8059)	NOPOP(8059)	ALL(8059)	Crohn's disease	HPOID:0100280	Crohn's disease	DOID:8778	Crohn's disease	D003424	Crohn Disease	EFOID:0000384	crohn's disease	Enteritis	Intestinal disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis

Mapped by lexical matching(Total Items:1)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0000010	Recurrent urinary tract infections	MP:0003617	urinary bladder hypoplasia;HP:0008046	Abnormality of the retinal vasculature

Mapped by homologous gene(Total Items:1)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0000010	Recurrent urinary tract infections	MP:0003257	abnormal abdominal wall morphology;HP:0002586	Peritonitis

Chemical(Total Drugs:8)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0010346	acetaminophen	D000082	103-90-2	crohn disease	MESH:D003424	therapeutic	21127120
C0010346	ampicillin	D000667	69-53-4	crohn disease	MESH:D003424	therapeutic	18319500
C0010346	aztreonam	D001398	78110-38-0	crohn disease	MESH:D003424	therapeutic	18319500
C0010346	chlordiazepoxide	D002707	58-25-3	crohn disease	MESH:D003424	therapeutic	18711101
C0010346	ciprofloxacin	D002939	85721-33-1	crohn disease	MESH:D003424	therapeutic	12399240
C0010346	linezolid	D000069349	-	crohn disease	MESH:D003424	therapeutic	18319500
C0010346	methotrexate	D008727	1959/5/2	crohn disease	MESH:D003424	therapeutic	10592889
C0010346	thalidomide	D013792	50-35-1	crohn disease	MESH:D003424	therapeutic	11339241

FDA approved drug and dosage information(Total Drugs:12)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D003424	zyvox	linezolid	400MG Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	TABLET;ORAL	Discontinued	None	Yes	No
MESH:D003424	zyvox	linezolid	200MG/100ML (2MG/ML)	SOLUTION;IV (INFUSION)	Prescription	AP	Yes	No
MESH:D003424	zyvox	linezolid	100MG/5ML	FOR SUSPENSION;ORAL	Prescription	AB	Yes	Yes
MESH:D003424	zyvox	linezolid	400MG Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	TABLET;ORAL	Discontinued	None	Yes	No
MESH:D003424	zyvox	linezolid	200MG/100ML (2MG/ML)	SOLUTION;IV (INFUSION)	Prescription	AP	Yes	No
MESH:D003424	zyvox	linezolid	100MG/5ML	FOR SUSPENSION;ORAL	Prescription	AB	Yes	Yes
MESH:D003424	cipro	ciprofloxacin	400MG/40ML (10MG/ML)	INJECTABLE;INJECTION	Discontinued	None	Yes	No
MESH:D003424	cipro	ciprofloxacin	250MG/5ML	FOR SUSPENSION;ORAL	Prescription	AB	Yes	No
MESH:D003424	ofirmev	acetaminophen	1GM/100ML (10MG/ML)	SOLUTION;IV (INFUSION)	Prescription	AP	Yes	Yes
MESH:D003424	ofirmev	acetaminophen	1GM/100ML (10MG/ML)	SOLUTION;IV (INFUSION)	Prescription	AP	Yes	Yes
MESH:D003424	acetaminophen	acetaminophen	650MG	SUPPOSITORY;RECTAL	Over-the-counter	None	Yes	Yes
MESH:D003424	acetaminophen	acetaminophen	650MG	SUPPOSITORY;RECTAL	Over-the-counter	None	Yes	Yes

FDA labeling changes(Total Drugs:12)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D003424	12/19/2002	zyvox	linezolid	Nosocomial pneumonia, community-acquired pneumonia, complicated and uncomplicated skin and skin structure infections, and vancomycin-resistant infections caused by susceptible strains	Extended age range down to birth for nosocomial pneumonia, community-acquired pneumonia, complicated skin and skin structure infections and vancomycin-resistant infections. Safety and efficacy extrapolated from studies in adults and supported by PK and comparator-controlled studies in patients from birth to 11 years Extended age range down to 5 years of age for uncomplicated skin and skin structure infections based upon a comparator-controlled study in 5 to 17 year olds Clearance of linezolid varies as a function of age; As age of pediatric patients increases, clearance gradually decreases, and by adolescence mean clearance values approach those observed in adults Pediatric patients exhibit wider variability in clearance and systemic exposure (AUC) compared with adults New every 8 hours dosing regimen for pediatric patients birth to 11 years of age and every 12 hours dosing regimen for pediatric patients 12 years and older Information on PK parameters, AE profile, laboratory changes, dosing, and clinical studies	Labeling	B	-	-	-	Pfizer	11/2/2005	FALSE'
MESH:D003424	12/19/2002	zyvox	linezolid	Nosocomial pneumonia, community-acquired pneumonia, complicated and uncomplicated skin and skin structure infections, and vancomycin-resistant infections caused by susceptible strains	Extended age range down to birth for nosocomial pneumonia, community-acquired pneumonia, complicated skin and skin structure infections and vancomycin-resistant infections. Safety and efficacy extrapolated from studies in adults and supported by PK and comparator-controlled studies in patients from birth to 11 years Extended age range down to 5 years of age for uncomplicated skin and skin structure infections based upon a comparator-controlled study in 5 to 17 year olds Clearance of linezolid varies as a function of age; As age of pediatric patients increases, clearance gradually decreases, and by adolescence mean clearance values approach those observed in adults Pediatric patients exhibit wider variability in clearance and systemic exposure (AUC) compared with adults New every 8 hours dosing regimen for pediatric patients birth to 11 years of age and every 12 hours dosing regimen for pediatric patients 12 years and older Information on PK parameters, AE profile, laboratory changes, dosing, and clinical studies	Labeling	B	-	-	-	Pfizer	11/2/2005	FALSE'
MESH:D003424	12/19/2002	zyvox	linezolid	Nosocomial pneumonia, community-acquired pneumonia, complicated and uncomplicated skin and skin structure infections, and vancomycin-resistant infections caused by susceptible strains	Extended age range down to birth for nosocomial pneumonia, community-acquired pneumonia, complicated skin and skin structure infections and vancomycin-resistant infections. Safety and efficacy extrapolated from studies in adults and supported by PK and comparator-controlled studies in patients from birth to 11 years Extended age range down to 5 years of age for uncomplicated skin and skin structure infections based upon a comparator-controlled study in 5 to 17 year olds Clearance of linezolid varies as a function of age; As age of pediatric patients increases, clearance gradually decreases, and by adolescence mean clearance values approach those observed in adults Pediatric patients exhibit wider variability in clearance and systemic exposure (AUC) compared with adults New every 8 hours dosing regimen for pediatric patients birth to 11 years of age and every 12 hours dosing regimen for pediatric patients 12 years and older Information on PK parameters, AE profile, laboratory changes, dosing, and clinical studies	Labeling	B	-	-	-	Pfizer	11/2/2005	FALSE'
MESH:D003424	12/5/2005	zyvox	linezolid	Central nervous system infections	PK data in pediatric patients with ventriculoperitoneal shunts showed variable cerebrospinal fluid (CSF) concentrations; therapeutic concentrations were not consistently achieved or maintained in the CSF Use of linezolid for the empiric treatment of pediatric patients with central nervous system infections is not recommended Additional information on efficacy in pediatric patients with infectious vancomycin-resistant Enterococcus faecium	Labeling	B	-	-	-	Pfizer	11/2/2005	FALSE'
MESH:D003424	12/5/2005	zyvox	linezolid	Central nervous system infections	PK data in pediatric patients with ventriculoperitoneal shunts showed variable cerebrospinal fluid (CSF) concentrations; therapeutic concentrations were not consistently achieved or maintained in the CSF Use of linezolid for the empiric treatment of pediatric patients with central nervous system infections is not recommended Additional information on efficacy in pediatric patients with infectious vancomycin-resistant Enterococcus faecium	Labeling	B	-	-	-	Pfizer	11/2/2005	FALSE'
MESH:D003424	12/5/2005	zyvox	linezolid	Central nervous system infections	PK data in pediatric patients with ventriculoperitoneal shunts showed variable cerebrospinal fluid (CSF) concentrations; therapeutic concentrations were not consistently achieved or maintained in the CSF Use of linezolid for the empiric treatment of pediatric patients with central nervous system infections is not recommended Additional information on efficacy in pediatric patients with infectious vancomycin-resistant Enterococcus faecium	Labeling	B	-	-	-	Pfizer	11/2/2005	FALSE'
MESH:D003424	03/25/2004	cipro	ciprofloxacin	Complicated UTI and pyelonephritis	Indicated for the treatment of complicated urinary tract infections (cUTIs) and pyelonephritis in pediatric patients 1 17 years of age Not drug of first choice due to increased adverse events compared to controls including events related to joints and/or surrounding tissues Information on PK and dose in pediatric patients 1 17 years of age The most frequent adverse events observed within 6 weeks of treatment initiation during the cUTI clinical trial were gastrointestinal 15% compared to 9% and musculoskeletal 9.3% compared to 6% in ciprofloxacin-treated compared to control-treated patients, respectively	Labeling	B	-	-	-	Bayer	12/18/2003	FALSE'
MESH:D003424	03/25/2004	cipro	ciprofloxacin	Complicated UTI and pyelonephritis	Indicated for the treatment of complicated urinary tract infections (cUTIs) and pyelonephritis in pediatric patients 1 17 years of age Not drug of first choice due to increased adverse events compared to controls including events related to joints and/or surrounding tissues Information on PK and dose in pediatric patients 1 17 years of age The most frequent adverse events observed within 6 weeks of treatment initiation during the cUTI clinical trial were gastrointestinal 15% compared to 9% and musculoskeletal 9.3% compared to 6% in ciprofloxacin-treated compared to control-treated patients, respectively	Labeling	B	-	-	-	Bayer	12/18/2003	FALSE'
MESH:D003424	2/11/2010	ofirmev	acetaminophen	Management of mild-to-moderate pain, for the management of moderate-to-severe pain with adjunctive opioid analgesics, and for the reduction of fever	The safety and effectiveness of Ofirmev for the treatment of acute pain and fever in pediatric patients ages 2 years and older is supported by evidence from adequate and well-controlled studies of Ofirmev in adults. Additional safety and PK data was collected in 355 from premature neonates to adolescents. The effectiveness of Ofirmev for the treatment of acute pain and fever has not been studied in pediatric patients < 2 years of age.The PK exposure of Ofirmev observed in children and adolescents is similar to adults, but higher in neonates and infants. Dosing simulations from PK data in infants and neonates suggest that dose reductions of 33% in infants 1 month to < 2 years of age, and 50% in neonates up to 28 days, with a minimum dosing interval of 6 hours, will produce a PK exposure similar to that observed in children age 2 years and olderMost common adverse reactions in pediatric patients were nausea, vomiting, constipation, pruritus, agitation, and atelectasis.Information on dosing, clinical studies, adverse reactions and PK parametersNew dosage form and route of administration	Labeling	-	P	-	-	Cadence	-	FALSE'
MESH:D003424	01/27/2017	ofirmev	acetaminophen	Treatmeny of pain and fever in pediatric patients birth to 2 years	Treatment of pain Efficacy was not demonstrated in pediatric patients younger than 2 years in a double-blind, placebo-controlled study of 198 pediatric patients younger than 2 years. Pediatric patients less than 2 years of age, including neonates from 28 to 40 weeks gestational age at birth, were randomized to receive opioid plus acetaminophen or opioid plus placebo. No difference in analgesic effect of intravenous acetaminophen, measured by assessment of reduced need for additional opioid treatment for pain control, was observed. Treatment of fever The safety and effectiveness for the treatment of fever in pediatric patients, including premature neonates born at 32 weeks or greater gestation is supported by adequate and well-controlled studies of Ofirmev in adults, clinical studies in 244 pediatric patients 2 years and older, and safety and pharmacokinetic data from 239 patients younger than 2 years including neonates 32 weeks or greater gestational age. Information on dosing, clinical trials. Postmarketing study.	Labeling	-	-	B,P	-	Mallinckrodt	11/7/2016	FALSE
MESH:D003424	2/11/2010	ofirmev	acetaminophen	Management of mild-to-moderate pain, for the management of moderate-to-severe pain with adjunctive opioid analgesics, and for the reduction of fever	The safety and effectiveness of Ofirmev for the treatment of acute pain and fever in pediatric patients ages 2 years and older is supported by evidence from adequate and well-controlled studies of Ofirmev in adults. Additional safety and PK data was collected in 355 from premature neonates to adolescents. The effectiveness of Ofirmev for the treatment of acute pain and fever has not been studied in pediatric patients < 2 years of age.The PK exposure of Ofirmev observed in children and adolescents is similar to adults, but higher in neonates and infants. Dosing simulations from PK data in infants and neonates suggest that dose reductions of 33% in infants 1 month to < 2 years of age, and 50% in neonates up to 28 days, with a minimum dosing interval of 6 hours, will produce a PK exposure similar to that observed in children age 2 years and olderMost common adverse reactions in pediatric patients were nausea, vomiting, constipation, pruritus, agitation, and atelectasis.Information on dosing, clinical studies, adverse reactions and PK parametersNew dosage form and route of administration	Labeling	-	P	-	-	Cadence	-	FALSE'
MESH:D003424	01/27/2017	ofirmev	acetaminophen	Treatmeny of pain and fever in pediatric patients birth to 2 years	Treatment of pain Efficacy was not demonstrated in pediatric patients younger than 2 years in a double-blind, placebo-controlled study of 198 pediatric patients younger than 2 years. Pediatric patients less than 2 years of age, including neonates from 28 to 40 weeks gestational age at birth, were randomized to receive opioid plus acetaminophen or opioid plus placebo. No difference in analgesic effect of intravenous acetaminophen, measured by assessment of reduced need for additional opioid treatment for pain control, was observed. Treatment of fever The safety and effectiveness for the treatment of fever in pediatric patients, including premature neonates born at 32 weeks or greater gestation is supported by adequate and well-controlled studies of Ofirmev in adults, clinical studies in 244 pediatric patients 2 years and older, and safety and pharmacokinetic data from 239 patients younger than 2 years including neonates 32 weeks or greater gestational age. Information on dosing, clinical trials. Postmarketing study.	Labeling	-	-	B,P	-	Mallinckrodt	11/7/2016	FALSE