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Pediatric Disease Annotations & Medicines



   coronary thrombosis
  

Disease ID 676
Disease coronary thrombosis
Definition
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.
Synonym
coronary artery thrombosis
coronary artery thrombosis (disorder)
coronary thromboses
coronary thrombosis [disease/finding]
ct - coronary thrombosis
thromboses, coronary
thrombosis - coronary
thrombosis coronary
thrombosis, coronary
DOID
UMLS
C0010072
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:16)
C0027051  |  myocardial infarction  |  9
C0027051  |  myocardial infarct  |  9
C0155626  |  acute myocardial infarction  |  3
C0002965  |  unstable angina  |  1
C0043117  |  idiopathic thrombocytopenic purpura  |  1
C0034152  |  henoch-schonlein purpura  |  1
C0011880  |  diabetic ketoacidosis  |  1
C0027022  |  myeloproliferative disease  |  1
C0040053  |  thrombus  |  1
C1442837  |  myocardial necrosis  |  1
C0151744  |  myocardial ischemia  |  1
C0022116  |  ischemia  |  1
C0040034  |  thrombocytopenia  |  1
C0398623  |  hypercoagulability  |  1
C0018799  |  heart disease  |  1
C0010068  |  coronary heart disease  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:2)
ITGB3  |  3690  |  CTD_human
PLAT  |  5327  |  CTD_human
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:4)
1636  |  ACE  |  infer
183  |  AGT  |  infer
185  |  AGTR1  |  infer
2811  |  GP1BA  |  infer
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:71)
9352  |  TXNL1  |  DISEASES
2158  |  F9  |  DISEASES
5327  |  PLAT  |  DISEASES
5054  |  SERPINE1  |  DISEASES
10105  |  PPIF  |  DISEASES
7448  |  VTN  |  DISEASES
7128  |  TNFAIP3  |  DISEASES
391013  |  PLA2G2C  |  DISEASES
5176  |  SERPINF1  |  DISEASES
1401  |  CRP  |  DISEASES
967  |  CD63  |  DISEASES
25833  |  POU2F3  |  DISEASES
7450  |  VWF  |  DISEASES
3690  |  ITGB3  |  DISEASES
3674  |  ITGA2B  |  DISEASES
5033  |  P4HA1  |  DISEASES
6403  |  SELP  |  DISEASES
3827  |  KNG1  |  DISEASES
1462  |  VCAN  |  DISEASES
644  |  BLVRA  |  DISEASES
5972  |  REN  |  DISEASES
738  |  VPS51  |  DISEASES
1436  |  CSF1R  |  DISEASES
9372  |  ZFYVE9  |  DISEASES
1636  |  ACE  |  DISEASES
5473  |  PPBP  |  DISEASES
5196  |  PF4  |  DISEASES
3673  |  ITGA2  |  DISEASES
23305  |  ACSL6  |  DISEASES
5481  |  PPID  |  DISEASES
64805  |  P2RY12  |  DISEASES
948  |  CD36  |  DISEASES
2147  |  F2  |  DISEASES
51206  |  GP6  |  DISEASES
5340  |  PLG  |  DISEASES
9377  |  COX5A  |  DISEASES
147179  |  WIPF2  |  DISEASES
2149  |  F2R  |  DISEASES
5345  |  SERPINF2  |  DISEASES
7706  |  TRIM25  |  DISEASES
2811  |  GP1BA  |  DISEASES
29940  |  DSE  |  DISEASES
5104  |  SERPINA5  |  DISEASES
2152  |  F3  |  DISEASES
8654  |  PDE5A  |  DISEASES
51703  |  ACSL5  |  DISEASES
6288  |  SAA1  |  DISEASES
2224  |  FDPS  |  DISEASES
6525  |  SMTN  |  DISEASES
2157  |  F8  |  DISEASES
23038  |  WDTC1  |  DISEASES
462  |  SERPINC1  |  DISEASES
60495  |  HPSE2  |  DISEASES
959  |  CD40LG  |  DISEASES
774  |  CACNA1B  |  DISEASES
5900  |  RALGDS  |  DISEASES
5328  |  PLAU  |  DISEASES
286205  |  SCAI  |  DISEASES
4146  |  MATN1  |  DISEASES
2159  |  F10  |  DISEASES
2155  |  F7  |  DISEASES
1906  |  EDN1  |  DISEASES
114899  |  C1QTNF3  |  DISEASES
10284  |  SAP18  |  DISEASES
6152  |  RPL24  |  DISEASES
23066  |  CAND2  |  DISEASES
6915  |  TBXA2R  |  DISEASES
9127  |  P2RX6  |  DISEASES
6196  |  RPS6KA2  |  DISEASES
91  |  ACVR1B  |  DISEASES
102723508  |  KANTR  |  DISEASES
Locus(Waiting for update.)
Disease ID 676
Disease coronary thrombosis
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:9)
HP:0001658  |  Myocardial infarction  |  9
HP:0001953  |  Diabetic ketosis  |  1
HP:0100724  |  Hypercoagulability  |  1
HP:0001873  |  Low platelet count  |  1
HP:0100749  |  Thoracic pain  |  1
HP:0001700  |  Myocardial necrosis  |  1
HP:0011874  |  Heparin-induced thrombocytopenia  |  1
HP:0001993  |  Ketoacidosis  |  1
HP:0012531  |  Pain  |  1
Disease ID 676
Disease coronary thrombosis
Manually Symptom(Waiting for update.)
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:3)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:1)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs2243093117516712811GP1BAumls:C0010072BeFreePlatelet membrane glycoprotein Ibalpha gene -5T/C Kozak sequence polymorphism as an independent risk factor for the occurrence of coronary thrombosis.0.0026384742002GP1BA174932600TC
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:40)
CHR POS SNPID REF ALT ORI_SNPID PMID P_VALUE P_VALUE_TEXT OR/BETA CI95_TEXT GWAS_INITIAL_SAMPLE_SIZE SUB_POPULATION SUPER_POPULATION GWAS_TRAIT HPO_ID HPO_TERM DO_ID DO_TERM MESH_ID MESH_TERM EFO_ID EFO_TERM DOLITE_TERM RISK_ALLELE PUBLICATION_TYPE AA GENE_SYMBOL TYPE REFGENE
1169455982rs2038024CArs2038024231880481.75E-09NANANA2618 womenNOPOP(2618)ALL(2618)NOPOP(2618)ALL(2618)Activated protein C resistanceHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, Non-U.S. Gov'tTNA
1169481223rs6427196CGrs6427196231880482.11E-28NANANA2618 womenNOPOP(2618)ALL(2618)NOPOP(2618)ALL(2618)Activated protein C resistanceHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, Non-U.S. Gov'tGF5
1169490401rs6682179TCrs6682179231880481.43E-28NANANA2618 womenNOPOP(2618)ALL(2618)NOPOP(2618)ALL(2618)Activated protein C resistanceHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, Non-U.S. Gov'tCF5
1169498834rs6009TCrs6009231880481.24E-27NANANA2618 womenNOPOP(2618)ALL(2618)NOPOP(2618)ALL(2618)Activated protein C resistanceHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, Non-U.S. Gov'tCF5
1169519049rs6025TCrs6025231880484.20E-104NANANA2618 womenNOPOP(2618)ALL(2618)NOPOP(2618)ALL(2618)Activated protein C resistanceHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, Non-U.S. Gov'tGNA
260679226rs2058703GArs2058703214784284.23E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTBCL11A
3186390627rs9898CTrs9898231880485.26E-11NANANA2618 womenNOPOP(2618)ALL(2618)NOPOP(2618)ALL(2618)Activated protein C resistanceHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, Non-U.S. Gov'tTHRG
3186394038rs16860992GCrs16860992231880482.29E-15NANANA2618 womenNOPOP(2618)ALL(2618)NOPOP(2618)ALL(2618)Activated protein C resistanceHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, Non-U.S. Gov'tGHRG
3186395113rs2228243AGrs2228243231880489.55E-15NANANA2618 womenNOPOP(2618)ALL(2618)NOPOP(2618)ALL(2618)Activated protein C resistanceHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, Non-U.S. Gov'tAHRG
780220608rs2065668CTrs2065668214784287.65E-04Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTNA
780226885rs7807607CTrs7807607214784282.11E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTNA
780229221rs11771839GTrs11771839214784285.12E-04Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralGNA
780234243rs17154155GTrs17154155214784281.63E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralGCD36
780235846rs10499858AGrs10499858214784284.78E-04Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralACD36
780238463rs1761662CTrs1761662214784281.76E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
780244939rs1761667GArs1761667214784284.17E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralGCD36
780245921rs11971740AGrs11971740214784281.08E-05Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralG,ACD36
780248001rs4731642AGrs4731642214784282.24E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralACD36
780249319rs6960369GArs6960369214784285.77E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralGCD36
780250122rs10480808ATrs10480808214784288.07E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
780252295rs12706912ACrs12706912214784285.15E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralACD36
780252518rs4545029TGrs4545029214784286.59E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
780253911rs1537593TCrs1537593214784281.46E-04Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralGCD36
780258810rs10499859AGrs10499859214784289.21E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralACD36
780263001rs9784998CTrs9784998214784289.51E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralCCD36
780266736rs9918586TCrs9918586214784284.29E-05Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
780271108rs1534314GArs1534314214784282.31E-05Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
780275455rs1049654ACrs1049654214784285.60E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralACD36
780278107rs3211817TGrs3211817214784289.51E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
780278563rs3211821AGrs3211821214784285.84E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralACD36
780279718rs3211830CTrs3211830214784289.51E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralCCD36
780282636rs3211842GArs3211842214784282.18E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralGCD36
780283323rs3211849AGrs3211849214784281.72E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralACD36
780286940rs3211867CArs3211867214784289.51E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralACD36
780287152rs3211869TArs3211869214784281.13E-04Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
780287209rs3211870CTrs3211870214784281.27E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
780288385rs1358337GArs1358337214784283.44E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
780289043rs3211883ATrs3211883214784282.98E-04Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralACD36
780291398rs1924GArs1924214784289.51E-06Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
780294810rs3211916TCrs3211916214784283.08E-04Platelet CD36 expressionNANA374 European ancestry subjectsEuropean(374)ALL(374)EUR(374)ALL(374)Platelet CD36 surface expressionHPOID:0001872Abnormality of thrombocytesDOID:11847coronary thrombosisNANANANAVascular diseaseNAResearch Support, N.I.H., ExtramuralTCD36
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:7)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0010072bivalirudinC074619128270-60-0coronary thrombosisMESH:D003328therapeutic15084542
C0010072epirubicinD01525156420-45-2coronary thrombosisMESH:D003328marker/mechanism2720892
C0010072lepirudinC083544-coronary thrombosisMESH:D003328therapeutic17955717
C0010072epoprostenolD01146435121-78-9coronary thrombosisMESH:D003328therapeutic6363581
C0010072tenecteplaseC121182-coronary thrombosisMESH:D003328therapeutic20723251
C0010072ticlopidineD01398855142-85-3coronary thrombosisMESH:D003328marker/mechanism17507105
C0010072vincristineD014750-coronary thrombosisMESH:D003328marker/mechanism11724093
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)