coronary thrombosis |
Disease ID | 676 |
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Disease | coronary thrombosis |
Integrated Phenotype | (Waiting for update.) |
Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:9) HP:0001658 | Myocardial infarction | 9 HP:0001953 | Diabetic ketosis | 1 HP:0100724 | Hypercoagulability | 1 HP:0001873 | Low platelet count | 1 HP:0100749 | Thoracic pain | 1 HP:0001700 | Myocardial necrosis | 1 HP:0011874 | Heparin-induced thrombocytopenia | 1 HP:0001993 | Ketoacidosis | 1 HP:0012531 | Pain | 1 |
Disease ID | 676 |
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Disease | coronary thrombosis |
Manually Symptom | (Waiting for update.) |
Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:3) |
Manually Genotype(Total Text Mining Genotypes:0) |
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(Waiting for update.) |
All Snps(Total Genotypes:1) | |||||||||||||
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snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
rs2243093 | 11751671 | 2811 | GP1BA | umls:C0010072 | BeFree | Platelet membrane glycoprotein Ibalpha gene -5T/C Kozak sequence polymorphism as an independent risk factor for the occurrence of coronary thrombosis. | 0.002638474 | 2002 | GP1BA | 17 | 4932600 | T | C |
GWASdb Annotation(Total Genotypes:0) | |
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(Waiting for update.) |
GWASdb Snp Trait(Total Genotypes:40) | |||||||||||||||||||||||||||||
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CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
1 | 169455982 | rs2038024 | C | A | rs2038024 | 23188048 | 1.75E-09 | NA | NA | NA | 2618 women | NOPOP(2618) | ALL(2618) | NOPOP(2618) | ALL(2618) | Activated protein C resistance | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, Non-U.S. Gov't | T | NA |
1 | 169481223 | rs6427196 | C | G | rs6427196 | 23188048 | 2.11E-28 | NA | NA | NA | 2618 women | NOPOP(2618) | ALL(2618) | NOPOP(2618) | ALL(2618) | Activated protein C resistance | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, Non-U.S. Gov't | G | F5 |
1 | 169490401 | rs6682179 | T | C | rs6682179 | 23188048 | 1.43E-28 | NA | NA | NA | 2618 women | NOPOP(2618) | ALL(2618) | NOPOP(2618) | ALL(2618) | Activated protein C resistance | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, Non-U.S. Gov't | C | F5 |
1 | 169498834 | rs6009 | T | C | rs6009 | 23188048 | 1.24E-27 | NA | NA | NA | 2618 women | NOPOP(2618) | ALL(2618) | NOPOP(2618) | ALL(2618) | Activated protein C resistance | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, Non-U.S. Gov't | C | F5 |
1 | 169519049 | rs6025 | T | C | rs6025 | 23188048 | 4.20E-104 | NA | NA | NA | 2618 women | NOPOP(2618) | ALL(2618) | NOPOP(2618) | ALL(2618) | Activated protein C resistance | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, Non-U.S. Gov't | G | NA |
2 | 60679226 | rs2058703 | G | A | rs2058703 | 21478428 | 4.23E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | BCL11A |
3 | 186390627 | rs9898 | C | T | rs9898 | 23188048 | 5.26E-11 | NA | NA | NA | 2618 women | NOPOP(2618) | ALL(2618) | NOPOP(2618) | ALL(2618) | Activated protein C resistance | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, Non-U.S. Gov't | T | HRG |
3 | 186394038 | rs16860992 | G | C | rs16860992 | 23188048 | 2.29E-15 | NA | NA | NA | 2618 women | NOPOP(2618) | ALL(2618) | NOPOP(2618) | ALL(2618) | Activated protein C resistance | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, Non-U.S. Gov't | G | HRG |
3 | 186395113 | rs2228243 | A | G | rs2228243 | 23188048 | 9.55E-15 | NA | NA | NA | 2618 women | NOPOP(2618) | ALL(2618) | NOPOP(2618) | ALL(2618) | Activated protein C resistance | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, Non-U.S. Gov't | A | HRG |
7 | 80220608 | rs2065668 | C | T | rs2065668 | 21478428 | 7.65E-04 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | NA |
7 | 80226885 | rs7807607 | C | T | rs7807607 | 21478428 | 2.11E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | NA |
7 | 80229221 | rs11771839 | G | T | rs11771839 | 21478428 | 5.12E-04 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | G | NA |
7 | 80234243 | rs17154155 | G | T | rs17154155 | 21478428 | 1.63E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | G | CD36 |
7 | 80235846 | rs10499858 | A | G | rs10499858 | 21478428 | 4.78E-04 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | A | CD36 |
7 | 80238463 | rs1761662 | C | T | rs1761662 | 21478428 | 1.76E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
7 | 80244939 | rs1761667 | G | A | rs1761667 | 21478428 | 4.17E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | G | CD36 |
7 | 80245921 | rs11971740 | A | G | rs11971740 | 21478428 | 1.08E-05 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | G,A | CD36 |
7 | 80248001 | rs4731642 | A | G | rs4731642 | 21478428 | 2.24E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | A | CD36 |
7 | 80249319 | rs6960369 | G | A | rs6960369 | 21478428 | 5.77E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | G | CD36 |
7 | 80250122 | rs10480808 | A | T | rs10480808 | 21478428 | 8.07E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
7 | 80252295 | rs12706912 | A | C | rs12706912 | 21478428 | 5.15E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | A | CD36 |
7 | 80252518 | rs4545029 | T | G | rs4545029 | 21478428 | 6.59E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
7 | 80253911 | rs1537593 | T | C | rs1537593 | 21478428 | 1.46E-04 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | G | CD36 |
7 | 80258810 | rs10499859 | A | G | rs10499859 | 21478428 | 9.21E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | A | CD36 |
7 | 80263001 | rs9784998 | C | T | rs9784998 | 21478428 | 9.51E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | C | CD36 |
7 | 80266736 | rs9918586 | T | C | rs9918586 | 21478428 | 4.29E-05 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
7 | 80271108 | rs1534314 | G | A | rs1534314 | 21478428 | 2.31E-05 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
7 | 80275455 | rs1049654 | A | C | rs1049654 | 21478428 | 5.60E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | A | CD36 |
7 | 80278107 | rs3211817 | T | G | rs3211817 | 21478428 | 9.51E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
7 | 80278563 | rs3211821 | A | G | rs3211821 | 21478428 | 5.84E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | A | CD36 |
7 | 80279718 | rs3211830 | C | T | rs3211830 | 21478428 | 9.51E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | C | CD36 |
7 | 80282636 | rs3211842 | G | A | rs3211842 | 21478428 | 2.18E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | G | CD36 |
7 | 80283323 | rs3211849 | A | G | rs3211849 | 21478428 | 1.72E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | A | CD36 |
7 | 80286940 | rs3211867 | C | A | rs3211867 | 21478428 | 9.51E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | A | CD36 |
7 | 80287152 | rs3211869 | T | A | rs3211869 | 21478428 | 1.13E-04 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
7 | 80287209 | rs3211870 | C | T | rs3211870 | 21478428 | 1.27E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
7 | 80288385 | rs1358337 | G | A | rs1358337 | 21478428 | 3.44E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
7 | 80289043 | rs3211883 | A | T | rs3211883 | 21478428 | 2.98E-04 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | A | CD36 |
7 | 80291398 | rs1924 | G | A | rs1924 | 21478428 | 9.51E-06 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
7 | 80294810 | rs3211916 | T | C | rs3211916 | 21478428 | 3.08E-04 | Platelet CD36 expression | NA | NA | 374 European ancestry subjects | European(374) | ALL(374) | EUR(374) | ALL(374) | Platelet CD36 surface expression | HPOID:0001872 | Abnormality of thrombocytes | DOID:11847 | coronary thrombosis | NA | NA | NA | NA | Vascular disease | NA | Research Support, N.I.H., Extramural | T | CD36 |
Mapped by lexical matching(Total Items:0) |
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(Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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(Waiting for update.) |
Chemical(Total Drugs:7) | |||||||||
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CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
C0010072 | bivalirudin | C074619 | 128270-60-0 | coronary thrombosis | MESH:D003328 | therapeutic | 15084542 | ||
C0010072 | epirubicin | D015251 | 56420-45-2 | coronary thrombosis | MESH:D003328 | marker/mechanism | 2720892 | ||
C0010072 | lepirudin | C083544 | - | coronary thrombosis | MESH:D003328 | therapeutic | 17955717 | ||
C0010072 | epoprostenol | D011464 | 35121-78-9 | coronary thrombosis | MESH:D003328 | therapeutic | 6363581 | ||
C0010072 | tenecteplase | C121182 | - | coronary thrombosis | MESH:D003328 | therapeutic | 20723251 | ||
C0010072 | ticlopidine | D013988 | 55142-85-3 | coronary thrombosis | MESH:D003328 | marker/mechanism | 17507105 | ||
C0010072 | vincristine | D014750 | - | coronary thrombosis | MESH:D003328 | marker/mechanism | 11724093 |
FDA approved drug and dosage information(Total Drugs:0) | |
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(Waiting for update.) |
FDA labeling changes(Total Drugs:0) | |
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(Waiting for update.) |