PedAM
Pediatric Disease Annotations & Medicines
| conversion disorder | ||||
| Disease ID | 881 |
|---|---|
| Disease | conversion disorder |
| Definition | A disorder whose predominant feature is a loss or alteration in physical functioning that suggests a physical disorder but that is actually a direct expression of a psychological conflict or need. |
| Synonym | conversion dis conversion disorder (disorder) conversion disorder [disease/finding] conversion disorder, nos conversion disorders conversion hysteria conversion hysteria or reaction conversion hysterias conversion hysterical neurosis conversion neurosis conversion reaction conversion reactions conversions disorder hysteria hysteria conversion type hysteria, conversion hysterias, conversion hysterical disorder hysterical neurosis, conversion type neurosis conversion psychologic conversion disorder psychologic conversion disorder (disorder) psychologic conversion disorder (finding) psychologic conversion disorder, nos reaction conversion reaction, conversion reactions, conversion |
| DOID | |
| UMLS | C0009946 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:9) C0012746 | dissociative disorder | 1 C0011570 | depression | 1 C0036457 | scrapie | 1 C0002020 | alexithymia | 1 C0014544 | epilepsy | 1 C0020604 | hypochondriasis | 1 C0007758 | cerebellar ataxia | 1 C0078981 | arachnoid cyst | 1 C0004134 | ataxia | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:25) 6583 | SLC22A4 | DISEASES 4852 | NPY | DISEASES 2033 | EP300 | DISEASES 4924 | NUCB1 | DISEASES 55749 | CCAR1 | DISEASES 57332 | CBX8 | DISEASES 5409 | PNMT | DISEASES 150094 | SIK1 | DISEASES 1392 | CRH | DISEASES 2895 | GRID2 | DISEASES 23522 | KAT6B | DISEASES 6285 | S100B | DISEASES 79158 | GNPTAB | DISEASES 5340 | PLG | DISEASES 3266 | ERAS | DISEASES 10193 | RNF41 | DISEASES 5697 | PYY | DISEASES 1312 | COMT | DISEASES 257 | ALX3 | DISEASES 2316 | FLNA | DISEASES 2332 | FMR1 | DISEASES 8544 | PIR | DISEASES 83696 | TRAPPC9 | DISEASES 627 | BDNF | DISEASES 820 | CAMP | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 881 |
|---|---|
| Disease | conversion disorder |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:6) HP:0001250 | Seizures | 2 HP:0100702 | Arachnoid cyst | 1 HP:0001297 | Cerebral vascular events | 1 HP:0001288 | Gait disturbance | 1 HP:0000716 | Depression | 1 HP:0002354 | Memory loss | 1 |
| Disease ID | 881 |
|---|---|
| Disease | conversion disorder |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:4) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
Chemical(Total Drugs:1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0009946 | methylphenidate | D008774 | 113-45-1 | conversion disorder | MESH:D003291 | marker/mechanism | 4019811 | ||
FDA approved drug and dosage information(Total Drugs:3) | ||||||||
|---|---|---|---|---|---|---|---|---|
| DiseaseID | Drug_name | active_ingredients | strength | Dosage Form/Route | Marketing Status | TE code | RLD | RS |
| MESH:D003291 | daytrana | methylphenidate | 10MG/9HR (1.1MG/HR) | FILM, EXTENDED RELEASE;TRANSDERMAL | Prescription | None | Yes | No |
| MESH:D003291 | daytrana | methylphenidate | 10MG/9HR (1.1MG/HR) | FILM, EXTENDED RELEASE;TRANSDERMAL | Prescription | None | Yes | No |
| MESH:D003291 | daytrana | methylphenidate | 10MG/9HR (1.1MG/HR) | FILM, EXTENDED RELEASE;TRANSDERMAL | Prescription | None | Yes | No |
FDA labeling changes(Total Drugs:3) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DiseaseID | Pediatric_Labeling_Date | Trade_Name | Generic_Name_or_Proper_Name | Indications Studied | Label Changes Summary | Product Labeling | BPCA(B) | PREA(P) | BPCA(B) and PREA(P) | Pediatric Rule (R) | Sponsor | Pediatric Exclusivity Granted Date | NNPS |
| MESH:D003291 | 6/4/2006 | daytrana | methylphenidate | ADHD | Summary is pending | Labeling | - | P | - | - | Shire | - | FALSE' |
| MESH:D003291 | 12/14/2009 | daytrana | methylphenidate | Postmarketing safety study | Information added to Warnings and Adverse Reactions on skin reactions observed in a postmarketing dermal study in pediatric patients | Labeling | - | P | - | - | Shire | - | FALSE' |
| MESH:D003291 | 06/29/2010 | daytrana | methylphenidate | ADHD | Expanded pediatric indication to include adolescent patients ages13-17 years The most commonly reported adverse reactions in a trial in patients 13-17 years included appetite decreased, nausea, insomnia, weight decreased, dizziness, abdominal pain, and anorexia. The majority of patients had erythema at the application site Information on PK parameters, Adverse Event profile and clinical studies | Labeling | - | P | - | - | Shire | - | FALSE' |