PedAM

Pediatric Disease Annotations & Medicines


	constrictive pericarditis

Disease ID	1517
Disease	constrictive pericarditis
Definition	Inflammation of the PERICARDIUM that is characterized by the fibrous scarring and adhesion of both serous layers, the VISCERAL PERICARDIUM and the PARIETAL PERICARDIUM leading to the loss of pericardial cavity. The thickened pericardium severely restricts cardiac filling. Clinical signs include FATIGUE, muscle wasting, and WEIGHT LOSS.
Synonym	constrictiv pericarditis constrictive pericarditides constrictive pericarditis (disorder) constrictive pericarditis nos constrictive pericarditis nos (disorder) pericarditides, constrictive pericarditis constrictive pericarditis, constrictive pericarditis, constrictive [disease/finding]
DOID	DOID:11481
UMLS	C0031048
MeSH	D010494
SNOMED-CT	SNOMEDCT_US_2016_09_01:85598007
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:34) C0018801 \| heart failure \| 10 C0031046 \| pericarditis \| 4 C0041296 \| tuberculosis \| 4 C0031039 \| pericardial effusion \| 2 C0040100 \| thymoma \| 2 C0018802 \| congestive heart failure \| 2 C1335381 \| pericardial mesothelioma \| 2 C0007177 \| cardiac tamponade \| 2 C0018799 \| heart disease \| 2 C0033680 \| protein-losing enteropathy \| 2 C0032708 \| porphyria \| 2 C0007196 \| restrictive cardiomyopathy \| 1 C0003873 \| rheumatoid arthritis \| 1 C0002726 \| amyloidosis \| 1 C0023788 \| whipple's disease \| 1 C0162566 \| porphyria cutanea tarda \| 1 C0022661 \| end-stage renal disease \| 1 C0037116 \| silicosis \| 1 C0032285 \| pneumonia \| 1 C0023434 \| chronic lymphatic leukemia \| 1 C0031039 \| pericardial effusions \| 1 C0878544 \| cardiomyopathy \| 1 C0019064 \| hemopericardium \| 1 C0023448 \| lymphatic leukemia \| 1 C0023890 \| cirrhosis \| 1 C0022658 \| renal disease \| 1 C0021831 \| enteropathy \| 1 C0041321 \| miliary tuberculosis \| 1 C0003486 \| aortic aneurysm \| 1 C1135196 \| diastolic heart failure \| 1 C0023890 \| liver cirrhosis \| 1 C0023895 \| hepatopathy \| 1 C0878675 \| erdheim-chester disease \| 1 C0004943 \| behcet's disease \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:43) 4210 \| MEFV \| DISEASES 3381 \| IBSP \| DISEASES 6783 \| SULT1E1 \| DISEASES 4256 \| MGP \| DISEASES 6908 \| TBP \| DISEASES 6678 \| SPARC \| DISEASES 7291 \| TWIST1 \| DISEASES 2006 \| ELN \| DISEASES 6737 \| TRIM21 \| DISEASES 1401 \| CRP \| DISEASES 3357 \| HTR2B \| DISEASES 3557 \| IL1RN \| DISEASES 4591 \| TRIM37 \| DISEASES 1356 \| CP \| DISEASES 64083 \| GOLPH3 \| DISEASES 5972 \| REN \| DISEASES 4851 \| NOTCH1 \| DISEASES 7547 \| ZIC3 \| DISEASES 909 \| CD1A \| DISEASES 1636 \| ACE \| DISEASES 89858 \| SIGLEC12 \| DISEASES 213 \| ALB \| DISEASES 160065 \| PATE1 \| DISEASES 64388 \| GREM2 \| DISEASES 117178 \| SSX2IP \| DISEASES 7137 \| TNNI3 \| DISEASES 23481 \| PES1 \| DISEASES 5265 \| SERPINA1 \| DISEASES 58 \| ACTA1 \| DISEASES 28514 \| DLL1 \| DISEASES 7139 \| TNNT2 \| DISEASES 7390 \| UROS \| DISEASES 1244 \| ABCC2 \| DISEASES 100 \| ADA \| DISEASES 9314 \| KLF4 \| DISEASES 3055 \| HCK \| DISEASES 4879 \| NPPB \| DISEASES 650 \| BMP2 \| DISEASES 94 \| ACVRL1 \| DISEASES 1363 \| CPE \| DISEASES 10216 \| PRG4 \| DISEASES 5817 \| PVR \| DISEASES 102723508 \| KANTR \| DISEASES
Locus	(Waiting for update.)

Disease ID	1517
Disease	constrictive pericarditis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:31) HP:0001635 \| Congestive heart failure \| 10 HP:0001541 \| Ascites \| 5 HP:0001701 \| Pericarditis \| 4 HP:0002202 \| Pleural effusion \| 2 HP:0100004 \| Pericardial mesothelioma \| 2 HP:0100522 \| Thymoma \| 2 HP:0001698 \| Pericardial effusions \| 2 HP:0012281 \| Chylous ascites \| 2 HP:0002243 \| Protein-losing enteropathy \| 2 HP:0010310 \| Chylothorax \| 2 HP:0006532 \| Pneumonia, recurrent episodes \| 1 HP:0011034 \| Amyloid disease \| 1 HP:0011851 \| Hemopericardium \| 1 HP:0001394 \| Hepatic cirrhosis \| 1 HP:0002090 \| Pneumonia \| 1 HP:0004942 \| Aortic aneurysm \| 1 HP:0002631 \| Ascending aortic aneurysm \| 1 HP:0001723 \| Restrictive cardiomyopathy \| 1 HP:0100749 \| Thoracic pain \| 1 HP:0002240 \| Enlarged liver \| 1 HP:0000969 \| Dropsy \| 1 HP:0001708 \| Impaired right ventricular function \| 1 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0001279 \| Syncope \| 1 HP:0001638 \| Cardiomyopathy \| 1 HP:0030149 \| Cardiovascular shock \| 1 HP:0002242 \| Enteropathy \| 1 HP:0001631 \| Atria septal defect \| 1 HP:0003774 \| End-stage renal failure \| 1 HP:0005550 \| Chronic lymphatic leukemia \| 1 HP:0002955 \| Granulomatosis \| 1

Disease ID	1517
Disease	constrictive pericarditis
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:10) C0018801 \| heart failure \| 10 C0007177 \| cardiac tamponade \| 2 C0008733 \| chylothorax \| 2 C0033680 \| protein-losing enteropathy \| 2 C0008732 \| chylous ascites \| 2 C0019209 \| hepatomegaly \| 1 C0018817 \| atrial septal defect \| 1 C0162566 \| porphyria cutanea tarda \| 1 C0018816 \| septal defect \| 1 C0240708 \| pericardial calcification \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0031048	methysergide	D008784	361-37-5	pericarditis, constrictive	MESH:D010494	marker/mechanism	626452

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

Web
Analytics