PedAM
Pediatric Disease Annotations & Medicines
| complex partial epilepsy | ||||
| Disease ID | 1052 |
|---|---|
| Disease | complex partial epilepsy |
| Definition | A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8) |
| Synonym | complex partial epileptic seizure complex partial epileptic seizure (disorder) complex partial seizure dis complex partial seizure disorder dis complex partial seizures disorder, complex partial seizures epilepsy psychomotor epilepsy, complex partial epilepsy, complex partial [disease/finding] epilepsy, psychic equivalent epilepsy, psychomotor partial complex epilepsy partial complex seizure disorder partial epilepsy, complex psychic equivalent epilepsy psychomotor epilepsy psychomotor epilepsy (disorder) seizure dis complex partial seizure disorder, complex partial |
| DOID | |
| UMLS | C0085417 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:1) |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:1) |
| Inferring Gene | Entrez_id | Symbol | Resource(Total Genes:1) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:33) 158 | ADSL | DISEASES 1113 | CHGA | DISEASES 23064 | SETX | DISEASES 8600 | TNFSF11 | DISEASES 5217 | PFN2 | DISEASES 6496 | SIX3 | DISEASES 2033 | EP300 | DISEASES 23476 | BRD4 | DISEASES 51102 | MECR | DISEASES 5443 | POMC | DISEASES 6389 | SDHA | DISEASES 51083 | GAL | DISEASES 2052 | EPHX1 | DISEASES 6750 | SST | DISEASES 762 | CA4 | DISEASES 5617 | PRL | DISEASES 43 | ACHE | DISEASES 7200 | TRH | DISEASES 171558 | PTCRA | DISEASES 9482 | STX8 | DISEASES 79641 | ROGDI | DISEASES 2055 | CLN8 | DISEASES 51738 | GHRL | DISEASES 3363 | HTR7 | DISEASES 23583 | SMUG1 | DISEASES 404552 | SCGB1D4 | DISEASES 9179 | AP4M1 | DISEASES 4000 | LMNA | DISEASES 4129 | MAOB | DISEASES 57282 | SLC4A10 | DISEASES 4988 | OPRM1 | DISEASES 6513 | SLC2A1 | DISEASES 4345 | CD200 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1052 |
|---|---|
| Disease | complex partial epilepsy |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:2) |
| Disease ID | 1052 |
|---|---|
| Disease | complex partial epilepsy |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
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All Snps(Total Genotypes:0) | |
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GWASdb Annotation(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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Mapped by lexical matching(Total Items:0) |
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Mapped by homologous gene(Total Items:0) |
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Chemical(Total Drugs:10) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0085417 | carbamazepine | D002220 | 298-46-4 | epilepsy, complex partial | MESH:D017029 | therapeutic | 10343150 | ||
| C0085417 | clozapine | D003024 | 5786-21-0 | epilepsy, complex partial | MESH:D017029 | marker/mechanism | 7950347 | ||
| C0085417 | gabapentin | C040029 | 60142-96-3 | epilepsy, complex partial | MESH:D017029 | therapeutic | 14733874 | ||
| C0085417 | lamotrigine | C047781 | 84057-84-1 | epilepsy, complex partial | MESH:D017029 | therapeutic | 14733874 | ||
| C0085417 | methotrexate | D008727 | 1959/5/2 | epilepsy, complex partial | MESH:D017029 | marker/mechanism | 1381940 | ||
| C0085417 | phenytoin | D010672 | 57-41-0 | epilepsy, complex partial | MESH:D017029 | marker/mechanism | 1797011 | ||
| C0085417 | phenytoin | D010672 | 57-41-0 | epilepsy, complex partial | MESH:D017029 | therapeutic | 10343150 | ||
| C0085417 | topiramate | C052342 | 97240-79-4 | epilepsy, complex partial | MESH:D017029 | therapeutic | 10880283 | ||
| C0085417 | valproic acid | D014635 | 99-66-1 | epilepsy, complex partial | MESH:D017029 | therapeutic | 10343150 | ||
| C0085417 | vigabatrin | D020888 | 60643-86-9 | epilepsy, complex partial | MESH:D017029 | therapeutic | 10880283 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
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FDA labeling changes(Total Drugs:0) | |
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