PedAM

Pediatric Disease Annotations & Medicines


	colorectal neoplasms

Disease ID	909
Disease	colorectal neoplasms
Definition	Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
Synonym	colorectal neopl colorectal neoplasm colorectal neoplasms [disease/finding] colorectal tumor colorectal tumors large bowel neoplasm large bowel tumor large intestinal neoplasm large intestine neoplasm large intestine tumor neopl colorectal neoplasm of large bowel neoplasm of large intestine neoplasm of large intestine (disorder) neoplasm of the large bowel neoplasm of the large intestine neoplasm, colorectal neoplasms, colorectal tumor of large bowel tumor of large intestine tumor of the large bowel tumor, colorectal tumors, colorectal tumour of large intestine
UMLS	C0009404
MeSH	D015179
SNOMED-CT	SNOMEDCT_US_2016_09_01:126837005
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:44) C0021390 \| inflammatory bowel disease \| 17 C0021831 \| bowel disease \| 11 C0009324 \| ulcerative colitis \| 9 C0009319 \| colitis \| 5 C0001430 \| adenoma \| 5 C0007113 \| rectal cancer \| 4 C0024623 \| gastric cancer \| 4 C1333990 \| lynch syndrome \| 4 C0009402 \| colorectal cancer \| 4 C0948265 \| metabolic syndrome \| 3 C0008313 \| sclerosing cholangitis \| 3 C0566602 \| primary sclerosing cholangitis \| 3 C0008311 \| cholangitis \| 3 C0494165 \| liver metastasis \| 3 C0494165 \| liver metastases \| 3 C0011849 \| diabetes mellitus \| 3 C0007570 \| celiac disease \| 2 C0011860 \| type 2 diabetes mellitus \| 2 C0032580 \| familial adenomatous polyposis \| 2 C0011860 \| type 2 diabetes \| 2 C0011847 \| diabetes \| 2 C0001418 \| adenocarcinoma \| 2 C1302401 \| colorectal adenoma \| 2 C0024623 \| stomach cancer \| 2 C0021390 \| inflammatory bowel diseases \| 2 C0010346 \| crohn's disease \| 1 C0476089 \| endometrial cancer \| 1 C0016977 \| gallbladder disease \| 1 C0156147 \| colonic crohn's disease \| 1 C0017152 \| gastritis \| 1 C0016977 \| gallbladder diseases \| 1 C0024623 \| gastric cancers \| 1 C0017154 \| chronic atrophic gastritis \| 1 C0007102 \| colon cancer \| 1 C0476089 \| endometrial ca \| 1 C0017154 \| atrophic gastritis \| 1 C0011860 \| diabetes mellitus type 2 \| 1 C0153446 \| anal cancer \| 1 C0019294 \| inguinal hernia \| 1 C0032580 \| adenomatous polyposis \| 1 C0007137 \| squamous cell carcinoma \| 1 C0014118 \| endocarditis \| 1 C0021843 \| intestinal obstruction \| 1 C0025202 \| melanoma \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:223) ABCB1 \| 5243 \| CTD_human TNF \| 7124 \| CTD_human NQO1 \| 1728 \| CTD_human SOD2 \| 6648 \| CTD_human PIK3CA \| 5290 \| CTD_human GRIN2A \| 2903 \| CTD_human TP53 \| 7157 \| CTD_human TGFB1 \| 7040 \| CTD_human BCL2 \| 596 \| CTD_human ABCB11 \| 8647 \| CTD_human ABCA1 \| 19 \| CTD_human CALR \| 811 \| CTD_human ABCG2 \| 9429 \| CTD_human CASP8 \| 841 \| CTD_human DPYD \| 1806 \| CTD_human MSH2 \| 4436 \| CTD_human NXN \| 64359 \| CTD_human ABCB6 \| 10058 \| CTD_human AMACR \| 23600 \| CTD_human SMAD4 \| 4089 \| CTD_human MMP1 \| 4312 \| CTD_human KDR \| 3791 \| CTD_human ODC1 \| 4953 \| CTD_human BMP4 \| 652 \| CTD_human STRAP \| 11171 \| CTD_human GNB4 \| 59345 \| CTD_human CCND1 \| 595 \| CTD_human IGF2 \| 3481 \| CTD_human PLA2G2A \| 5320 \| CTD_human CSF2 \| 1437 \| CTD_human PTGS2 \| 5743 \| CTD_human CHD5 \| 26038 \| CTD_human ABCG1 \| 9619 \| CTD_human TNFSF10 \| 8743 \| CTD_human RET \| 5979 \| CTD_human PROM1 \| 8842 \| CTD_human NRAS \| 4893 \| CTD_human ABCC8 \| 6833 \| CTD_human BUB1B \| 701 \| CTD_human AKT1 \| 207 \| CTD_human TYMS \| 7298 \| CTD_human APC \| 324 \| CTD_human ERCC2 \| 2068 \| CTD_human EFEMP1 \| 2202 \| CTD_human NAMPT \| 10135 \| CTD_human CYP1B1 \| 1545 \| CTD_human EIF3H \| 8667 \| CTD_human CHEK2 \| 11200 \| CTD_human IFNA2 \| 3440 \| CTD_human TCN2 \| 6948 \| CTD_human ATP7B \| 540 \| CTD_human AKR1B10 \| 57016 \| CTD_human MTHFR \| 4524 \| CTD_human MMP2 \| 4313 \| CTD_human BRAF \| 673 \| CTD_human GREM1 \| 26585 \| CTD_human BOLL \| 66037 \| CTD_human GATA4 \| 2626 \| CTD_human CYP2A6 \| 1548 \| CTD_human ABCB4 \| 5244 \| CTD_human RHPN2 \| 85415 \| CTD_human TP63 \| 8626 \| CTD_human PAX8 \| 7849 \| CTD_human FGFR3 \| 2261 \| CTD_human COL7A1 \| 1294 \| CTD_human CTNNB1 \| 1499 \| CTD_human EYA4 \| 2070 \| CTD_human PPARG \| 5468 \| CTD_human POSTN \| 10631 \| CTD_human GUCY2C \| 2984 \| CTD_human CFTR \| 1080 \| CTD_human GGH \| 8836 \| CTD_human BIRC5 \| 332 \| CTD_human KRAS \| 3845 \| CTD_human EGFR \| 1956 \| CTD_human ABCC13 \| 150000 \| CTD_human GRID1 \| 2894 \| CTD_human FLCN \| 201163 \| CTD_human GPX4 \| 2879 \| CTD_human TGFBR1 \| 7046 \| CTD_human MTRR \| 4552 \| CTD_human SPARC \| 6678 \| CTD_human EP300 \| 2033 \| CTD_human FADS2 \| 9415 \| CTD_human TCERG1L \| 256536 \| CTD_human AURKA \| 6790 \| CTD_human RNF182 \| 221687 \| CTD_human ZNF432 \| 9668 \| CTD_human APC2 \| 10297 \| CTD_human PTPRD \| 5789 \| CTD_human NR4A2 \| 4929 \| CTD_human PYCARD \| 29108 \| CTD_human SLC19A1 \| 6573 \| CTD_human NME1 \| 4830 \| CTD_human ABCB10 \| 23456 \| CTD_human SYNE1 \| 23345 \| CTD_human ARNT \| 405 \| CTD_human ALDH2 \| 217 \| CTD_human EPHA1 \| 2041 \| CTD_human TLR4 \| 7099 \| CTD_human UMPS \| 7372 \| CTD_human GSTM1 \| 2944 \| CTD_human TLR2 \| 7097 \| CTD_human IL6ST \| 3572 \| CTD_human ESR2 \| 2100 \| CTD_human ABCC6 \| 368 \| CTD_human FPGS \| 2356 \| CTD_human MLH1 \| 4292 \| CTD_human MLH3 \| 27030 \| CTD_human PDGFRL \| 5157 \| CTD_human MIR106B \| 406900 \| CTD_human TRPM7 \| 54822 \| CTD_human TCF7L2 \| 6934 \| CTD_human FOXL2 \| 668 \| CTD_human PTPRJ \| 5795 \| CTD_human CD226 \| 10666 \| CTD_human MIR93 \| 407050 \| CTD_human ABCC2 \| 1244 \| CTD_human ABCC3 \| 8714 \| CTD_human ABCC1 \| 4363 \| CTD_human ABCC4 \| 10257 \| CTD_human ABCC5 \| 10057 \| CTD_human NT5C \| 30833 \| CTD_human CABLES1 \| 91768 \| CTD_human SCG5 \| 6447 \| CTD_human SFRP1 \| 6422 \| CTD_human ABCE1 \| 6059 \| CTD_human PRKD1 \| 5587 \| CTD_human FAT1 \| 2195 \| CTD_human LY96 \| 23643 \| CTD_human DHFR \| 1719 \| CTD_human GUCY1A2 \| 2977 \| CTD_human SERPINB5 \| 5268 \| CTD_human PRKCE \| 5581 \| CTD_human LAMA1 \| 284217 \| CTD_human ADH1B \| 125 \| CTD_human TFRC \| 7037 \| CTD_human SOX17 \| 64321 \| CTD_human GALNT12 \| 79695 \| CTD_human CXCL8 \| 3576 \| CTD_human SFRP2 \| 6423 \| CTD_human CD109 \| 135228 \| CTD_human SELENBP1 \| 8991 \| CTD_human MKI67 \| 4288 \| CTD_human SFRP4 \| 6424 \| CTD_human SFRP5 \| 6425 \| CTD_human TYMP \| 1890 \| CTD_human NME2 \| 4831 \| CTD_human NEURL1 \| 9148 \| CTD_human LGR6 \| 59352 \| CTD_human HOXD1 \| 3231 \| CTD_human HOXD9 \| 3235 \| CTD_human GPNMB \| 10457 \| CTD_human CDH1 \| 999 \| CTD_human TXNRD1 \| 7296 \| CTD_human ZMIZ1 \| 57178 \| CTD_human NRCAM \| 4897 \| CTD_human DCC \| 1630 \| CTD_human PPM1E \| 22843 \| CTD_human TP53TG1 \| 11257 \| CTD_human GSTM3 \| 2947 \| CTD_human ABCD4 \| 5826 \| CTD_human IFNA1 \| 3439 \| CTD_human XAF1 \| 54739 \| CTD_human ZKSCAN3 \| 80317 \| CTD_human IGFBP3 \| 3486 \| CTD_human ICAM5 \| 7087 \| CTD_human RRM2 \| 6241 \| CTD_human FEN1 \| 2237 \| CTD_human TK1 \| 7083 \| CTD_human EXO1 \| 9156 \| CTD_human EVL \| 51466 \| CTD_human POLD1 \| 5424 \| CTD_human CDH7 \| 1005 \| CTD_human CDH5 \| 1003 \| CTD_human POLD3 \| 10714 \| CTD_human ABCA4 \| 24 \| CTD_human FLNC \| 2318 \| CTD_human ZNF569 \| 148266 \| CTD_human CD9 \| 928 \| CTD_human NTNG1 \| 22854 \| CTD_human VTI1A \| 143187 \| CTD_human FBLN2 \| 2199 \| CTD_human MIR1273C \| 100422821 \| CTD_human ABCA3 \| 21 \| CTD_human ABCA5 \| 23461 \| CTD_human ABCA8 \| 10351 \| CTD_human ABCA6 \| 23460 \| CTD_human POLE \| 5426 \| CTD_human JPH3 \| 57338 \| CTD_human CYP1A2 \| 1544 \| CTD_human WIF1 \| 11197 \| CTD_human SLC22A15 \| 55356 \| CTD_human CPAMD8 \| 27151 \| CTD_human ABCD3 \| 5825 \| CTD_human ABCD2 \| 225 \| CTD_human STARD8 \| 9754 \| CTD_human PRKCB \| 5579 \| CTD_human SMAD7 \| 4092 \| CTD_human TFPI2 \| 7980 \| CTD_human MIR130B \| 406920 \| CTD_human UNG \| 7374 \| CTD_human CABYR \| 26256 \| CTD_human HAPLN1 \| 1404 \| CTD_human FBN2 \| 2201 \| CTD_human DCLK1 \| 9201 \| CTD_human ABCA12 \| 26154 \| CTD_human ABCA13 \| 154664 \| CTD_human ABCA10 \| 10349 \| CTD_human ZNF292 \| 23036 \| CTD_human AXIN2 \| 8313 \| CTD_human PPP1R14A \| 94274 \| CTD_human FADS1 \| 3992 \| CTD_human GATA5 \| 140628 \| CTD_human ACKR3 \| 57007 \| CTD_human ABCB5 \| 340273 \| CTD_human ABCA9 \| 10350 \| CTD_human RNF43 \| 54894 \| CTD_human TNFSF13 \| 8741 \| CTD_human MIR26B \| 407017 \| CTD_human SH3TC1 \| 54436 \| CTD_human CTBP1 \| 1487 \| CTD_human LRRC3B \| 116135 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:104) 196 \| AHR \| infer 324 \| APC \| infer 328 \| APEX1 \| infer 367 \| AR \| infer 405 \| ARNT \| infer 472 \| ATM \| infer 8312 \| AXIN1 \| infer 580 \| BARD1 \| infer 673 \| BRAF \| infer 672 \| BRCA1 \| infer 675 \| BRCA2 \| infer 9994 \| CASP8AP2 \| infer 875 \| CBS \| infer 595 \| CCND1 \| infer 902 \| CCNH \| infer 978 \| CDA \| infer 999 \| CDH1 \| infer 1022 \| CDK7 \| infer 1026 \| CDKN1A \| infer 1027 \| CDKN1B \| infer 1029 \| CDKN2A \| infer 1030 \| CDKN2B \| infer 11200 \| CHEK2 \| infer 1499 \| CTNNB1 \| infer 1543 \| CYP1A1 \| infer 1544 \| CYP1A2 \| infer 1545 \| CYP1B1 \| infer 29118 \| DDX25 \| infer 57609 \| DIP2B \| infer 1807 \| DPYS \| infer 11221 \| DUSP10 \| infer 2067 \| ERCC1 \| infer 2068 \| ERCC2 \| infer 2072 \| ERCC4 \| infer 2073 \| ERCC5 \| infer 2177 \| FANCD2 \| infer 2189 \| FANCG \| infer 355 \| FAS \| infer 1647 \| GADD45A \| infer 59345 \| GNB4 \| infer 2950 \| GSTP1 \| infer 3265 \| HRAS \| infer 3845 \| KRAS \| infer 220959 \| KRT8P16 \| infer 3911 \| LAMA5 \| infer 3978 \| LIG1 \| infer 3980 \| LIG3 \| infer 3981 \| LIG4 \| infer 4255 \| MGMT \| infer 4292 \| MLH1 \| infer 4312 \| MMP1 \| infer 4316 \| MMP7 \| infer 4318 \| MMP9 \| infer 4436 \| MSH2 \| infer 4437 \| MSH3 \| infer 2956 \| MSH6 \| infer 4524 \| MTHFR \| infer 4548 \| MTR \| infer 4552 \| MTRR \| infer 4595 \| MUTYH \| infer 4619 \| MYH1 \| infer 55892 \| MYNN \| infer 10 \| NAT2 \| infer 4683 \| NBN \| infer 4780 \| NFE2L2 \| infer 1728 \| NQO1 \| infer 4893 \| NRAS \| infer 4907 \| NT5E \| infer 4968 \| OGG1 \| infer 142 \| PARP1 \| infer 143 \| PARP4 \| infer 5111 \| PCNA \| infer 5290 \| PIK3CA \| infer 5395 \| PMS2 \| infer 5423 \| POLB \| infer 5783 \| PTPN13 \| infer 5887 \| RAD23B \| infer 5888 \| RAD51 \| infer 5893 \| RAD52 \| infer 25788 \| RAD54B \| infer 5883 \| RAD9A \| infer 5965 \| RECQL \| infer 85415 \| RHPN2 \| infer 9501 \| RPH3AL \| infer 100271596 \| RPS3AP46 \| infer 6447 \| SCG5 \| infer 4092 \| SMAD7 \| infer 401475 \| SRRM1P1 \| infer 6926 \| TBX3 \| infer 7157 \| TP53 \| infer 7158 \| TP53BP1 \| infer 7159 \| TP53BP2 \| infer 7161 \| TP73 \| infer 7227 \| TRPS1 \| infer 7298 \| TYMS \| infer 51733 \| UPB1 \| infer 7421 \| VDR \| infer 7507 \| XPA \| infer 7508 \| XPC \| infer 7515 \| XRCC1 \| infer 7516 \| XRCC2 \| infer 7517 \| XRCC3 \| infer 7518 \| XRCC4 \| infer 7520 \| XRCC5 \| infer
Text Mined Gene	(Waiting for update.)
Locus	(Waiting for update.)

Disease ID	909
Disease	colorectal neoplasms
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:26) HP:0100279 \| Ulcerative colitis \| 9 HP:0012126 \| Gastric cancer \| 6 HP:0002583 \| Colitis \| 5 HP:0000819 \| Diabetes mellitus \| 3 HP:0002664 \| Neoplasia \| 3 HP:0030151 \| Cholangitis \| 3 HP:0000718 \| Aggressive behaviour \| 2 HP:0002608 \| Celiac disease \| 2 HP:0005202 \| Helicobacter pylori infection \| 2 HP:0003003 \| Colon cancer \| 1 HP:0005231 \| Chronic gastritis \| 1 HP:0100523 \| Hepatic abscess \| 1 HP:0005214 \| Bowel obstruction \| 1 HP:0002860 \| Squamous cell carcinoma \| 1 HP:0030731 \| Carcinoma \| 1 HP:0100584 \| Endocarditis \| 1 HP:0100280 \| Morbus Crohn \| 1 HP:0002582 \| Chronic atrophic gastritis \| 1 HP:0000752 \| Hyperactive behavior \| 1 HP:0002861 \| Melanoma \| 1 HP:0000023 \| Inguinal hernia \| 1 HP:0005266 \| Intestinal polyp \| 1 HP:0012450 \| Chronic constipation \| 1 HP:0005263 \| Gastritis \| 1 HP:0000855 \| Insulin resistance \| 1 HP:0100834 \| Neoplasm of the large intestine \| 1

Disease ID	909
Disease	colorectal neoplasms
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0494165 \| liver metastases \| 3 C0494165 \| liver metastasis \| 3

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:39)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs10411210	19011631	85415	RHPN2	umls:C0009404	GAD	[Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.]	0.122367032	2008	RHPN2	19	33041394	C	T
rs1045642	11980438	6934	TCF7L2	umls:C0009404	BeFree	Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability.	0.138789078	2002	ABCB1	7	87509329	A	T,G
rs1045642	11980438	6925	TCF4	umls:C0009404	BeFree	Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability.	0.002171535	2002	ABCB1	7	87509329	A	T,G
rs1045642	11980438	5243	ABCB1	umls:C0009404	BeFree	Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability.	0.133449998	2002	ABCB1	7	87509329	A	T,G
rs10936599	20972440	55892	MYNN	umls:C0009404	GAD	[Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.]	0.002367032	2010	MYNN	3	169774313	C	T
rs11169552	20972440	57609	DIP2B	umls:C0009404	GAD	[Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.]	0.002367032	2010	ATF1;LOC105369765	12	50761880	C	T
rs113488022	23536897	673	BRAF	umls:C0009404	BeFree	To verify the technical characteristics of the microarray system for the correct identification of the KRAS mutational status at the two hotspot codons 12 and 13 and of the BRAF(V600E) mutation in colorectal tumor, we selected 75 samples previously characterized by conventional and CO-amplification at Lower Denaturation temperature-PCR (COLD-PCR) followed by High Resolution Melting analysis and direct sequencing.	0.215741083	2013	BRAF	7	140753336	A	T,G,C
rs113488022	23536897	3845	KRAS	umls:C0009404	BeFree	To verify the technical characteristics of the microarray system for the correct identification of the KRAS mutational status at the two hotspot codons 12 and 13 and of the BRAF(V600E) mutation in colorectal tumor, we selected 75 samples previously characterized by conventional and CO-amplification at Lower Denaturation temperature-PCR (COLD-PCR) followed by High Resolution Melting analysis and direct sequencing.	0.322443416	2013	BRAF	7	140753336	A	T,G,C
rs113488022	19213871	673	BRAF	umls:C0009404	BeFree	Evaluation of high-resolution melting analysis as a diagnostic tool to detect the BRAF V600E mutation in colorectal tumors.	0.215741083	2009	BRAF	7	140753336	A	T,G,C
rs113488022	14668801	673	BRAF	umls:C0009404	BeFree	Recently, a V599E hotspot mutation within the BRAF gene was reported in a high percentage of colorectal tumors and significantly associated to defective mismatch repair (MMR).	0.215741083	2003	BRAF	7	140753336	A	T,G,C
rs113488022	20027224	673	BRAF	umls:C0009404	BeFree	Secondly, considering the alternative possibility, we identified genes whose DNA hypermethylation was closely linked to BRAF(V600E) and CIMP in 235 primary colorectal tumors.	0.215741083	2009	BRAF	7	140753336	A	T,G,C
rs1570360	18613756	7422	VEGFA	umls:C0009404	BeFree	According to our results, -1154 G/A and -460 C/T do not influence VEGF mRNA expression in colorectal tumors and susceptibility to sporadic colon cancer, although the role of other polymorphisms cannot be excluded.	0.055486896	2008	VEGFA	6	43770093	A	G
rs16892766	18372905	7227	TRPS1	umls:C0009404	GAD	[A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.]	0.004734064	2008	NA	8	116618444	A	C
rs16892766	21761138	7227	TRPS1	umls:C0009404	GAD	[Meta-analysis of new genome-wide association studies of colorectal cancer risk.]	0.004734064	2012	NA	8	116618444	A	C
rs16969681	25131200	1045	CDX2	umls:C0009404	BeFree	The intestine-specific transcription factor CDX2 and Wnt effector TCF7L2 bound near rs16969681, with significantly higher affinity for the risk allele, and CDX2 overexpression in CDX2/GREM1-negative cells caused re-expression of GREM1. rs16969681 influences CRC risk through effects on Wnt-driven GREM1 expression in colorectal tumors.	0.014707519	2014	NA	15	32700910	C	T
rs16969681	25131200	26585	GREM1	umls:C0009404	BeFree	The intestine-specific transcription factor CDX2 and Wnt effector TCF7L2 bound near rs16969681, with significantly higher affinity for the risk allele, and CDX2 overexpression in CDX2/GREM1-negative cells caused re-expression of GREM1. rs16969681 influences CRC risk through effects on Wnt-driven GREM1 expression in colorectal tumors.	0.120542884	2014	NA	15	32700910	C	T
rs16969681	25131200	6934	TCF7L2	umls:C0009404	BeFree	The intestine-specific transcription factor CDX2 and Wnt effector TCF7L2 bound near rs16969681, with significantly higher affinity for the risk allele, and CDX2 overexpression in CDX2/GREM1-negative cells caused re-expression of GREM1. rs16969681 influences CRC risk through effects on Wnt-driven GREM1 expression in colorectal tumors.	0.138789078	2014	NA	15	32700910	C	T
rs1801155	9724771	324	APC	umls:C0009404	BeFree	The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.	0.240791019	1998	APC	5	112839514	T	A
rs1801155	9751605	324	APC	umls:C0009404	BeFree	These findings support a model where somatic instability of the (A)8 tract produced by the APC I1307K allele leads to increased APC gene inactivation and directly accounts for 42% of the colorectal neoplasms occurring in APC I1307K carriers.	0.240791019	1998	APC	5	112839514	T	A
rs1801166	9724771	324	APC	umls:C0009404	BeFree	The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.	0.240791019	1998	APC	5	112839543	G	C
rs2032582	11980438	5243	ABCB1	umls:C0009404	BeFree	Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability.	0.133449998	2002	ABCB1	7	87531302	A	T,C
rs2032582	11980438	6934	TCF7L2	umls:C0009404	BeFree	Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability.	0.138789078	2002	ABCB1	7	87531302	A	T,C
rs2032582	11980438	6925	TCF4	umls:C0009404	BeFree	Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability.	0.002171535	2002	ABCB1	7	87531302	A	T,C
rs2229080	9440618	1630	DCC	umls:C0009404	BeFree	Codon 201Arg/Gly polymorphism of DCC (deleted in colorectal carcinoma) gene in flat- and polypoid-type colorectal tumors.	0.12953026	1997	DCC	18	52906232	C	G
rs25487	16931584	7515	XRCC1	umls:C0009404	GAD	[Multiplex pyrosequencing of two polymorphisms in DNA repair gene XRCC1.]	0.025099593	2006	XRCC1	19	43551574	T	C
rs3802842	18372901	120376	COLCA2	umls:C0009404	GAD	[Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.]	0.004734064	2008	COLCA2;COLCA1	11	111300984	C	A
rs3802842	21761138	120376	COLCA2	umls:C0009404	GAD	[Meta-analysis of new genome-wide association studies of colorectal cancer risk.]	0.004734064	2012	COLCA2;COLCA1	11	111300984	C	A
rs386425447	9440618	1630	DCC	umls:C0009404	BeFree	Codon 201Arg/Gly polymorphism of DCC (deleted in colorectal carcinoma) gene in flat- and polypoid-type colorectal tumors.	0.12953026	1997	NA	NA	NA	NA	NA
rs4779584	18372905	6447	SCG5	umls:C0009404	GAD	[A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.]	0.124734064	2008	NA	15	32702555	T	C
rs4779584	21761138	6447	SCG5	umls:C0009404	GAD	[Meta-analysis of new genome-wide association studies of colorectal cancer risk.]	0.124734064	2012	NA	15	32702555	T	C
rs4925386	20972440	3911	LAMA5	umls:C0009404	GAD	[Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.]	0.002367032	2010	LAMA5	20	62345988	T	C
rs4939827	18372901	4092	SMAD7	umls:C0009404	GAD	[Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.]	0.132192478	2008	SMAD7	18	48927093	T	C
rs4939827	21761138	4092	SMAD7	umls:C0009404	GAD	[Meta-analysis of new genome-wide association studies of colorectal cancer risk.]	0.132192478	2012	SMAD7	18	48927093	T	C
rs4939827	17934461	4092	SMAD7	umls:C0009404	GAD	[A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk.]	0.132192478	2007	SMAD7	18	48927093	T	C
rs4939827	18372905	4092	SMAD7	umls:C0009404	GAD	[A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.]	0.132192478	2008	SMAD7	18	48927093	T	C
rs6687758	20972440	11221	DUSP10	umls:C0009404	GAD	[Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.]	0.002367032	2010	NA	1	221991606	A	G
rs6691170	20972440	11221	DUSP10	umls:C0009404	GAD	[Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.]	0.002367032	2010	NA	1	221872104	G	T
rs7315438	21761138	6926	TBX3	umls:C0009404	GAD	[Meta-analysis of new genome-wide association studies of colorectal cancer risk.]	0.002638474	2012	LOC105370003	12	115453598	C	T
rs9929218	19011631	999	CDH1	umls:C0009404	GAD	[Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.]	0.163775169	2008	CDH1	16	68787043	G	A

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:758)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	5023321	rs12754637	G	A	rs12754637	19723657	5.33E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	G	NA
1	31203860	rs4949290	G	A	rs4949290	21242260	2.36E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
1	36159594	rs12048483	A	C	rs12048483	21239504	6.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	NA
1	67972435	rs12037907	A	C	rs12037907	19723657	8.14E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
1	86190666	rs2389972	A	G	rs2389972	22310351	0.000107	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced nausea/vomiting in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
1	90600934	rs6428571	C	T	rs6428571	21242260	1.19E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
1	97447183	rs10493889	T	C	rs10493889	17618283	8.00E-04	NA	NA	NA	1,257 cases; 1,336 controls	NOPOP(2593)	ALL(2593)	NOPOP(2593)	ALL(2593)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
1	100046246	rs6702619	T	G	rs6702619	22532847	0.000000577	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	NA
1	112613106	rs6691573	T	C	rs6691573	24836286	1.66E-04	(East Asian)	1.07	[1.03-1.10]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6691573-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
1	162776137	rs4656381	G	A	rs4656381	23266556	3.93E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162802615	rs2684879	C	A	rs2684879	23266556	4.11E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162803754	rs2805042	G	A	rs2805042	23266556	3.43E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162810754	rs2684880	C	T	rs2684880	23266556	3.23E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162813432	rs6699770	G	A	rs6699770	23266556	2.40E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162813583	rs6691351	A	G	rs6691351	23266556	1.71E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162813651	rs6679069	C	T	rs6679069	23266556	5.78E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162813950	rs10737489	T	C	rs10737489	23266556	1.24E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162816583	rs1892124	A	G	rs1892124	23266556	2.56E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162817400	rs10753591	C	T	rs10753591	23266556	8.17E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162818421	rs1858236	A	G	rs1858236	23266556	2.61E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	162821291	rs1912453	A	G	rs1912453	23266556	9.00E-06	NA	1.07	[1.04-1.11]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	176772958	rs1555070	T	C	rs1555070	22310351	0.000244	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced neuropathy in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
1	182973491	rs10752881	A	G	rs10752881	24836286	5.00E-06	(East Asian)	1.07	[1.04-1.10]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10752881-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
1	182982173	rs4487994	T	A	rs4487994	23266556	8.92E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182982303	rs4454510	G	A	rs4454510	23266556	9.94E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182982878	rs10752885	G	C	rs10752885	23266556	1.57E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182984524	rs10911191	T	C	rs10911191	23266556	9.32E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182988414	rs12126434	G	A	rs12126434	23266556	8.96E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182988608	rs10737236	T	C	rs10737236	23266556	8.99E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182989269	rs10737237	A	G	rs10737237	23266556	8.99E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182989366	rs10797813	C	T	rs10797813	23266556	8.82E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182990929	rs10797814	C	A	rs10797814	23266556	8.48E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182991355	rs6695746	T	C	rs6695746	23266556	8.77E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182991462	rs6695837	T	C	rs6695837	23266556	7.01E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182994084	rs4652763	A	G	rs4652763	23266556	8.74E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182994115	rs4652764	G	A	rs4652764	23266556	4.34E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	182996242	rs4642853	C	T	rs4642853	23266556	8.92E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183001312	rs4651138	C	A	rs4651138	23266556	8.29E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183002639	rs6678517	A	G	rs6678517	23266556	2.82E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183006911	rs10797819	A	G	rs10797819	23266556	1.03E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183008150	rs12043805	T	A	rs12043805	23266556	2.34E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183009196	rs4652769	T	C	rs4652769	23266556	1.05E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183009277	rs10911205	C	A	rs10911205	23266556	2.57E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183012423	rs10911206	A	G	rs10911206	23266556	1.12E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183013672	rs4366285	T	G	rs4366285	23266556	2.13E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183013988	rs10911209	T	G	rs10911209	23266556	1.10E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183014289	rs6660111	G	A	rs6660111	23266556	1.10E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183017345	rs6664995	T	C	rs6664995	23266556	1.10E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183017769	rs10797822	A	G	rs10797822	23266556	1.09E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183020762	rs4422969	G	A	rs4422969	23266556	9.14E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183021910	rs10752890	A	G	rs10752890	23266556	1.45E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183022299	rs10911211	A	T	rs10911211	23266556	2.56E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183023696	rs4652772	G	C	rs4652772	23266556	1.08E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183024469	rs10911212	C	T	rs10911212	23266556	1.08E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183025555	rs4546885	G	C	rs4546885	23266556	1.61E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183027432	rs3934579	G	A	rs3934579	23266556	1.08E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183027512	rs3934697	A	G	rs3934697	23266556	1.08E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183028430	rs10797828	G	A	rs10797828	23266556	9.41E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183028970	rs3935384	C	T	rs3935384	23266556	1.08E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183029070	rs4266836	T	G	rs4266836	23266556	1.02E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183033228	rs10797829	A	G	rs10797829	23266556	1.25E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183037695	rs6424883	T	C	rs6424883	23266556	2.20E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183042531	rs12120747	G	A	rs12120747	23266556	2.58E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183044034	rs10797832	A	G	rs10797832	23266556	1.23E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183047363	rs10911222	G	A	rs10911222	23266556	1.25E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183050368	rs10911229	C	G	rs10911229	23266556	1.26E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183052533	rs10911232	C	T	rs10911232	23266556	3.35E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183052585	rs10911233	G	A	rs10911233	23266556	2.84E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183053131	rs4397624	C	T	rs4397624	23266556	2.43E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183053746	rs10911235	G	A	rs10911235	23266556	1.34E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183054827	rs4652773	A	C,G	rs4652773	23266556	1.33E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183055398	rs2151669	T	G	rs2151669	23266556	1.33E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183058898	rs6672306	G	A	rs6672306	23266556	6.54E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183060917	rs4233194	G	C	rs4233194	23266556	7.87E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183065406	rs7525917	A	G	rs7525917	23266556	6.25E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183066254	rs6424885	T	G	rs6424885	23266556	6.37E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183071024	rs10752897	C	T	rs10752897	23266556	9.67E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183072590	rs2296288	T	C	rs2296288	23266556	7.79E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183072908	rs10797835	T	C	rs10797835	23266556	5.79E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183073266	rs2027075	A	G	rs2027075	23266556	6.61E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183073478	rs2027078	G	A	rs2027078	23266556	6.43E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183074415	rs2027080	C	T	rs2027080	23266556	6.46E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183075121	rs10797837	C	G	rs10797837	23266556	6.65E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183075456	rs2333622	T	C	rs2333622	23266556	6.70E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183075732	rs12091137	A	G	rs12091137	23266556	6.51E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183075778	rs12086466	T	C	rs12086466	23266556	7.42E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183076993	rs10911247	A	G	rs10911247	23266556	6.43E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183077020	rs10797838	A	G	rs10797838	23266556	6.22E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183077797	rs10797839	T	C	rs10797839	23266556	6.35E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183077896	rs10752898	T	C	rs10752898	23266556	7.67E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183078712	rs3768625	G	T	rs3768625	23266556	8.58E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183079252	rs3768624	C	T	rs3768624	23266556	6.44E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183079412	rs2296290	C	T	rs2296290	23266556	6.31E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183079509	rs2296291	C	T	rs2296291	23266556	6.58E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183079853	rs6672093	T	C	rs6672093	23266556	6.30E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183080690	rs10911249	G	A	rs10911249	23266556	6.77E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183081194	rs10911251	A	C	rs10911251	23266556	9.00E-08	NA	1.09	[1.06-1.13]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10911251-A	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183081867	rs10797842	G	A	rs10797842	23266556	1.15E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183084229	rs1537520	C	T	rs1537520	23266556	8.84E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183085304	rs6692207	T	C	rs6692207	23266556	7.84E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183085696	rs6424888	A	G	rs6424888	23266556	8.07E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183085755	rs20563	A	G	rs20563	23266556	6.08E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183086757	rs2296292	A	C	rs2296292	23266556	7.92E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183087727	rs10797848	A	G	rs10797848	23266556	8.60E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183088988	rs10797849	A	G	rs10797849	23266556	8.53E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183090011	rs3768622	G	A	rs3768622	23266556	7.98E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183090265	rs10752902	T	A	rs10752902	23266556	8.50E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183091796	rs6424889	G	C	rs6424889	23266556	8.54E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183091920	rs4652776	G	A	rs4652776	23266556	8.51E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183091963	rs4651139	C	T	rs4651139	23266556	8.52E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183091992	rs4652777	T	G	rs4652777	23266556	8.59E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183092237	rs3768620	G	A	rs3768620	23266556	8.55E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183092404	rs3768619	C	G	rs3768619	23266556	8.55E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183092500	rs3768617	C	T	rs3768617	23266556	2.86E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183093028	rs7518957	A	T	rs7518957	23266556	8.59E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183094191	rs2093982	T	C	rs2093982	23266556	4.40E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183094210	rs2093983	T	C	rs2093983	23266556	8.68E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183094322	rs2093985	C	T	rs2093985	23266556	3.55E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183094547	rs20558	T	C	rs20558	23266556	6.33E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183095024	rs1886499	C	T	rs1886499	23266556	3.08E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183095477	rs2296293	G	A	rs2296293	23266556	8.26E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183095596	rs2296294	T	C	rs2296294	23266556	1.94E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183095765	rs2224933	A	G	rs2224933	23266556	1.13E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183096634	rs1413390	G	A	rs1413390	23266556	9.26E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183096668	rs1413389	C	T	rs1413389	23266556	9.84E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183096774	rs1413387	G	A	rs1413387	23266556	9.89E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183096880	rs7529465	A	G	rs7529465	23266556	9.86E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183096952	rs4651140	G	T	rs4651140	23266556	9.90E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183096969	rs4651141	A	G	rs4651141	23266556	9.89E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183097398	rs4651143	A	G	rs4651143	23266556	9.82E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183099380	rs1360704	T	C	rs1360704	23266556	2.76E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183099701	rs2296300	G	A	rs2296300	23266556	8.18E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183099821	rs6691755	G	A	rs6691755	23266556	9.08E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183100555	rs2333620	T	C	rs2333620	23266556	9.01E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183100863	rs10752903	A	G	rs10752903	23266556	9.23E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183100884	rs10737245	G	A	rs10737245	23266556	9.22E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183101038	rs10752904	A	G	rs10752904	23266556	9.19E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183101302	rs10797852	C	T	rs10797852	23266556	9.35E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183101471	rs12061219	G	A	rs12061219	23266556	9.05E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183101686	rs12095664	G	A	rs12095664	23266556	7.29E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183103551	rs3768616	T	C	rs3768616	23266556	8.88E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183103604	rs3768615	A	G	rs3768615	23266556	8.72E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183106230	rs10911260	C	A	rs10911260	23266556	6.53E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183107446	rs2274984	G	T	rs2274984	23266556	1.29E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183108611	rs2027085	T	G	rs2027085	23266556	1.34E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183109034	rs729819	G	A	rs729819	23266556	1.27E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183112412	rs1062044	A	G	rs1062044	23266556	1.59E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183112505	rs944971	T	C	rs944971	23266556	2.65E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183112566	rs944970	T	C	rs944970	23266556	1.58E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183113862	rs3738829	C	T	rs3738829	23266556	1.31E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183113952	rs1547715	A	G	rs1547715	23266556	1.46E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183114119	rs1547714	C	T	rs1547714	23266556	1.51E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183114146	rs1051473	T	C	rs1051473	23266556	1.40E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183114634	rs7473	G	A	rs7473	23266556	1.43E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183114797	rs12034436	A	G	rs12034436	23266556	1.24E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	183114956	rs10911262	A	G	rs10911262	23266556	8.45E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
1	184402508	rs16823149	A	G	rs16823149	20610541	5.50E-08	Colorectal cancer	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
1	190569312	rs520227	G	C	rs520227	22310351	0.0000846	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced mucositis in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
1	204006538	rs4951291	T	C	rs4951291	19011631	5.30E-06	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	204006597	rs4951039	G	A	rs4951039	19011631	5.80E-06	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	222045446	rs6691170	G	T	rs6691170	20972440	1.00E-09	NA	1.06	[1.03-1.09]	3,334 European ancestry cases; 4,628 European ancestry controls	European(7962)	ALL(7962)	EUR(7962)	ALL(7962)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6691170-T	Research Support, Non-U.S. Gov't	G	NA
1	222061022	rs11118883	G	A	rs11118883	24737748	1.27E-04	NA	1.12	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs11118883-A	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
1	222164948	rs6687758	A	G	rs6687758	20972440	2.00E-09	NA	1.09	[1.06-1.12]	3,334 European ancestry cases; 4,628 European ancestry controls	European(7962)	ALL(7962)	EUR(7962)	ALL(7962)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6687758-G	Research Support, Non-U.S. Gov't	A	NA
1	222164948	rs6687758	A	G	rs6687758	24836286	9.00E-09	(East Asian)	1.12	[1.08-1.17]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6687758-G	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
1	226050609	rs10158985	C	A	rs10158985	22310351	0.000137	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced nausea/vomiting in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
1	237048500	rs1805087	A	G	rs1805087	21239504	1.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	MTR
2	943636	rs4971347	C	T	rs4971347	22310351	0.000027	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced diarrhea in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
2	29659854	rs4128317	A	C	rs4128317	22310351	0.0000735	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced mucositis in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
2	31005297	rs4597574	T	C	rs4597574	19723657	8.68E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	T	CAPN13
2	31603134	rs2163059	A	G	rs2163059	21242260	9.99E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	41950726	rs12994941	T	C	rs12994941	22532847	0.0000269	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer (males)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	NA
2	47153762	rs11690921	C	T	rs11690921	24737748	7.01E-04	NA	1.05	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs11690921-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	66966066	rs2901879	C	T	rs2901879	24743840	7.00E-07	(Red meat)	1.11	[1.06-1.16]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
2	75856492	rs10182133	A	C	rs10182133	22310351	0.000561	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced nausea/vomiting in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	97160382	rs6753667	G	A	rs6753667	21242260	1.75E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	97198800	rs2579502	T	C	rs2579502	21242260	1.48E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	97243532	rs2314109	C	T	rs2314109	21242260	1.35E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	97315570	rs17685664	C	T	rs17685664	21242260	9.93E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	98844674	rs7601049	C	G	rs7601049	21239504	2.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	VWA3B
2	98853173	rs11889349	G	A	rs11889349	21239504	2.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	VWA3B
2	106948443	rs4574118	C	G	rs4574118	20610541	1.80E-07	Colorectal cancer	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
2	109525530	rs260633	C	T	rs260633	21242260	2.50E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	111728482	rs4849303	C	T	rs4849303	24743840	1.00E-06	(Vegetable)	1.12	[1.08-1.18]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
2	113984503	rs2241975	C	T	rs2241975	24836286	5.97E-04	(East Asian)	1.09	[1.04-1.14]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2241975-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
2	130147336	rs1097701	G	A	rs1097701	22310351	0.000188	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced neuropathy in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	133542585	rs17325719	C	G	rs17325719	21239504	4.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	NCKAP5
2	179581835	rs2562832	C	A	rs2562832	21239504	1.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	TTN
2	179582537	rs2627043	G	T	rs2627043	22310351	0.000597	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced mucositis in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
2	179604160	rs1883085	T	G	rs1883085	21239504	1.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	TTN
2	179604366	rs2562829	T	G	rs2562829	21239504	1.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	TTN
2	179606538	rs2627037	G	A	rs2627037	21239504	1.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	TTN
2	192567912	rs12464838	G	T	rs12464838	23266556	3.66E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192567931	rs12469001	T	A	rs12469001	23266556	3.42E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192572805	rs6730901	T	C	rs6730901	23266556	4.14E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192575111	rs10931515	C	G	rs10931515	23266556	9.09E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192579683	rs10190843	G	A	rs10190843	23266556	3.66E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192580611	rs4425034	T	C	rs4425034	23266556	3.63E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192580887	rs4299283	A	G	rs4299283	23266556	5.10E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192580929	rs4477849	C	T	rs4477849	23266556	3.48E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192584206	rs4076769	G	A	rs4076769	23266556	3.96E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192585015	rs10202549	T	C	rs10202549	23266556	3.56E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192586829	rs13416906	G	A	rs13416906	23266556	3.50E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192587204	rs11903757	T	C	rs11903757	23266556	4.00E-08	NA	1.16	[1.10-1.22]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs11903757-C	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192588314	rs12475675	G	A	rs12475675	23266556	8.39E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192588334	rs12463776	T	C	rs12463776	23266556	3.00E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192589385	rs6717663	T	C	rs6717663	23266556	3.10E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192589399	rs6717668	T	C	rs6717668	23266556	3.39E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192589442	rs6731095	A	G	rs6731095	23266556	3.54E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192589454	rs6759665	C	A	rs6759665	23266556	1.72E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	192598024	rs12475230	C	G	rs12475230	23266556	5.39E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	206474012	rs17626122	T	C	rs17626122	22310351	0.0000595	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil and oxaliplatin combined induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	206474012	rs17626122	T	C	rs17626122	22310351	0.0000595	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	212808107	rs839533	A	G	rs839533	22310351	0.000159	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced mucositis in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
2	218883186	rs7580997	C	T	rs7580997	21242260	1.24E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	218894127	rs1427667	C	T	rs1427667	21242260	7.57E-07	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	218941916	rs4672870	C	T	rs4672870	23266556	6.57E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218942313	rs12694425	C	T	rs12694425	23266556	6.58E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218942351	rs12694426	T	G	rs12694426	23266556	6.67E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218942976	rs10932745	T	C	rs10932745	23266556	4.94E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218944615	rs11687200	A	G	rs11687200	23266556	5.60E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218944808	rs11676275	G	A	rs11676275	23266556	5.07E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218945045	rs12694427	G	A	rs12694427	23266556	5.43E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218945674	rs6737563	T	C	rs6737563	23266556	1.04E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218947515	rs13013361	A	T	rs13013361	23266556	8.94E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218951245	rs4133195	C	T	rs4133195	23266556	6.47E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218952233	rs6726126	G	A	rs6726126	23266556	9.71E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218952778	rs7422358	G	A	rs7422358	23266556	7.42E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218955809	rs10804264	T	C	rs10804264	23266556	3.77E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218958820	rs12694428	G	A	rs12694428	23266556	1.91E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218960680	rs13035513	C	T	rs13035513	23266556	1.11E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218964051	rs13007992	G	T	rs13007992	23266556	5.87E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218966315	rs7426289	C	T	rs7426289	23266556	1.56E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218977531	rs4674250	G	A	rs4674250	23266556	2.93E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218982862	rs6436032	T	C	rs6436032	23266556	9.66E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218988774	rs4674257	A	G	rs4674257	23266556	1.14E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218990586	rs4674258	C	T	rs4674258	23266556	6.92E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218991005	rs4674259	G	A	rs4674259	23266556	1.12E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	218997580	rs6723449	T	C	rs6723449	23266556	1.03E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219000734	rs1126579	T	C	rs1126579	23266556	1.04E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219000966	rs1126580	G	A	rs1126580	23266556	2.05E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219005009	rs4674261	G	C	rs4674261	23266556	2.86E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219007060	rs11677534	T	C	rs11677534	23266556	8.49E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219007752	rs13009946	T	G	rs13009946	23266556	9.97E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219008000	rs7594532	T	C	rs7594532	23266556	1.19E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219008392	rs7607437	A	G	rs7607437	23266556	1.14E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219010146	rs11676348	C	T	rs11676348	23266556	7.35E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219020914	rs13027120	T	C	rs13027120	23266556	1.06E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219026888	rs1008563	G	A	rs1008563	23266556	6.39E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	219026972	rs1008562	G	C	rs1008562	23266556	1.82E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
2	222027666	rs2019083	T	C	rs2019083	19723657	8.11E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	T	NA
2	224038435	rs6713755	A	C	rs6713755	22310351	0.0000317	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced diarrhoea in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
2	228669035	rs13389224	C	T	rs13389224	24737748	3.50E-04	NA	1.06	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs13389224-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
2	234997218	rs250944	G	A	rs250944	22310351	0.0000218	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced diarrhea in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	238449007	rs3817362	T	C	rs3817362	21239504	4.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	MLPH
3	23143047	rs4591517	C	T	rs4591517	23300701	3.00E-06	(rs4925386, known)	1.06	[0.88-1.29]	8,380 European ancestry cases; 10,558 European ancestry controls	European(18938)	ALL(18938)	EUR(18938)	ALL(18938)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
3	47388947	rs8180040	T	A	rs8180040	23350875	2.00E-06	NA	1.28	[1.15-1.41]	882 European ancestry cases; 473 European ancestry controls	European(1355)	ALL(1355)	EUR(1355)	ALL(1355)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	NA
3	64246829	rs704409	C	A	rs704409	19723657	9.48E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	T	NA
3	107398611	rs6779452	A	G	rs6779452	21242260	3.34E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
3	107399129	rs6782394	A	G	rs6782394	21242260	1.64E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
3	107401883	rs9848674	A	C	rs9848674	21242260	7.58E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
3	107404701	rs6789529	C	T	rs6789529	21242260	1.68E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	107461731	rs9875732	T	C	rs9875732	21242260	4.35E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	107464170	rs11710737	A	G	rs11710737	21242260	2.04E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
3	107471699	rs2049339	T	G	rs2049339	21242260	2.92E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	107479754	rs1403774	T	G	rs1403774	21242260	1.13E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	108703025	rs2593957	T	C	rs2593957	24743840	2.00E-06	(Fiber)	1.15	[1.09-1.20]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
3	108851484	rs4855695	T	C	rs4855695	24743840	2.00E-06	(Fiber)	1.14	[1.08-1.20]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
3	120491086	rs447978	G	A	rs447978	22310351	0.000135	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced neuropathy in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G,A
3	161264661	rs1506473	A	C	rs1506473	24448986	4.28E-05	NA	1.12	[1.06-1.19]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1506473-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	168871394	rs9809990	A	G	rs9809990	21242260	1.17E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	169492101	rs10936599	C	T	rs10936599	20972440	3.00E-08	NA	1.04	[1.04-1.10]	3,334 European ancestry cases; 4,628 European ancestry controls	European(7962)	ALL(7962)	EUR(7962)	ALL(7962)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10936599-C	Research Support, Non-U.S. Gov't	C	MYNN
3	169562965	rs116674307	T	C	rs116674307	24737748	6.40E-05	NA	1.13	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs116674307-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
3	173900575	rs16857540	C	G	rs16857540	22310351	0.000513	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced mucositis in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
3	178791678	rs9861291	C	G	rs9861291	22310351	0.0000747	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
3	180108963	rs7611300	C	A,T	rs7611300	22532847	0.00000163	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	NA
3	180108963	rs7611300	C	A,T	rs7611300	22532847	0.00000174	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer (males)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	NA
3	187753995	rs11710227	A	G	rs11710227	24448986	1.08E-04	NA	1.12	[1.05-1.19]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs11710227-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G,A
4	18315992	rs4140904	A	G	rs4140904	20610541	1.40E-07	Colorectal cancer	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
4	18795330	rs4147045	T	C	rs4147045	24743840	1.00E-06	(Vegetable)	1.2	[1.11-1.30]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
4	35047017	rs2054129	T	C	rs2054129	21242260	2.26E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
4	41758803	rs9283670	T	C	rs9283670	22532847	0.000141	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer (females)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	NA
4	67357454	rs17730929	A	C	rs17730929	23300701	3.00E-06	(rs7136702, known)	1.47	[1.25-1.72]	8,380 European ancestry cases; 10,558 European ancestry controls	European(18938)	ALL(18938)	EUR(18938)	ALL(18938)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
4	94838593	rs2578151	C	T	rs2578151	23266556	3.34E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94839209	rs13152714	A	C	rs13152714	23266556	1.76E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94839349	rs1898640	T	G	rs1898640	23266556	1.81E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94839419	rs1898639	A	G	rs1898639	23266556	1.89E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94839483	rs1898638	C	T	rs1898638	23266556	1.41E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94840017	rs2618735	T	C	rs2618735	23266556	1.26E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94841598	rs1370814	G	A	rs1370814	23266556	5.49E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94842269	rs2618740	G	T	rs2618740	23266556	1.78E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94842318	rs13129177	G	C	rs13129177	23266556	1.56E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94842437	rs2618741	T	C	rs2618741	23266556	5.44E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94842776	rs13105254	T	C	rs13105254	23266556	1.61E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94845993	rs2618743	T	C	rs2618743	23266556	8.41E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94847004	rs2578147	G	C	rs2578147	23266556	1.39E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94854453	rs1595502	C	T	rs1595502	23266556	1.57E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94858253	rs1837210	A	G	rs1837210	23266556	1.13E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94862267	rs1583661	C	A	rs1583661	23266556	9.22E-07	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94862679	rs2578137	G	C	rs2578137	23266556	9.85E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94862876	rs13147118	G	C	rs13147118	23266556	1.02E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94863753	rs10002699	T	A	rs10002699	23266556	1.03E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94865048	rs1438376	T	A	rs1438376	23266556	1.08E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94865274	rs7667693	T	C	rs7667693	23266556	9.80E-07	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94866291	rs1438374	C	T	rs1438374	23266556	1.32E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94866804	rs10006063	A	G	rs10006063	23266556	1.14E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94868191	rs2578133	T	A	rs2578133	23266556	7.69E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94868241	rs2618760	C	T	rs2618760	23266556	7.63E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94868270	rs2618761	G	T	rs2618761	23266556	7.65E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94869985	rs1579659	G	C	rs1579659	23266556	1.15E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94871350	rs13121186	C	T	rs13121186	23266556	1.17E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94875013	rs2618768	G	A	rs2618768	23266556	9.02E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94877850	rs2033781	A	C	rs2033781	23266556	2.70E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94881967	rs1370812	T	C	rs1370812	23266556	9.17E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94882341	rs10017390	G	A	rs10017390	23266556	1.24E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94883286	rs13113109	A	G	rs13113109	23266556	9.99E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94887031	rs13130787	T	C	rs13130787	23266556	3.00E-07	NA	1.09	[1.06-1.13]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94904738	rs17365288	A	G	rs17365288	23266556	1.08E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94913451	rs5021131	G	C	rs5021131	23266556	8.60E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94919390	rs11945480	A	G	rs11945480	23266556	9.07E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94920245	rs1438381	C	T	rs1438381	23266556	2.67E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94936015	rs11934535	A	G	rs11934535	23266556	8.95E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94938117	rs10030952	C	T	rs10030952	23266556	3.28E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94938945	rs1595511	A	G	rs1595511	23266556	3.89E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94943383	rs1370821	C	T	rs1370821	23266556	3.72E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94954026	rs13145086	T	A,G	rs13145086	23266556	7.78E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94955042	rs280063	T	A	rs280063	23266556	8.09E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94961303	rs280058	T	C	rs280058	23266556	2.27E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94964722	rs280054	A	G	rs280054	23266556	2.22E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94970758	rs280117	T	C	rs280117	23266556	2.99E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94973976	rs10016961	T	C	rs10016961	23266556	2.21E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94973985	rs280115	A	G	rs280115	23266556	2.56E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94983101	rs280078	T	C	rs280078	23266556	2.86E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	94984775	rs280076	T	C	rs280076	23266556	2.95E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
4	118663020	rs1870481	C	T	rs1870481	24978480	1.23E-07	NA	1.35	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1870481-T	Research Support, Non-U.S. Gov't	C	NA
4	118701446	rs1023890	G	A	rs1023890	24978480	5.61E-08	NA	1.36	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1023890-A	Research Support, Non-U.S. Gov't	T	NA
4	118707190	rs2169059	C	A	rs2169059	24978480	2.04E-07	NA	1.34	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2169059-A	Research Support, Non-U.S. Gov't	A	NA
4	118750348	rs1459528	T	C	rs1459528	24978480	4.57E-07	NA	1.33	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1459528-G	Research Support, Non-U.S. Gov't	G	NA
4	118759055	rs3987	A	G	rs3987	24978480	4.02E-08	NA	1.36	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs3987-C	Research Support, Non-U.S. Gov't	G	NA
4	138593451	rs2434137	T	C	rs2434137	19723657	2.32E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	G	NA
4	158969682	rs7664129	C	A	rs7664129	24978480	1.97E-04	NA	1.35	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs7664129-C	Research Support, Non-U.S. Gov't	C,A	NA
4	159092633	rs2881373	A	G	rs2881373	24978480	6.86E-06	NA	1.39	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2881373-T	Research Support, Non-U.S. Gov't	T	FAM198B
4	165364934	rs2874568	C	T	rs2874568	21242260	1.59E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
4	165683201	rs12650938	G	A	rs12650938	24448986	3.09E-05	NA	1.12	[1.06-1.19]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs12650938-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	183107423	rs2060645	T	C	rs2060645	22310351	0.000527	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced nausea/vomiting in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
4	188924979	rs6815391	C	T	rs6815391	22310351	0.000709	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced nausea/vomiting in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
5	204082	rs9312960	C	A	rs9312960	22310351	0.000191	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced neuropathy in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
5	314346	rs4957020	C	T	rs4957020	22310351	0.000191	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced neuropathy in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
5	3106162	rs314002	G	T	rs314002	24448986	3.73E-05	NA	1.14	[1.07-1.21]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs314002-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	16656570	rs588367	A	G	rs588367	24978480	1.30E-05	NA	1.32	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	NA
5	16656803	rs876095	A	G	rs876095	24978480	3.00E-05	NA	1.3	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	NA
5	16658495	rs428263	A	G	rs428263	24978480	2.60E-05	NA	1.3	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	NA
5	38496637	rs3729740	C	T	rs3729740	21239504	5.18E-05	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	LIFR
5	86094715	rs9293478	C	T	rs9293478	19723657	1.42E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	C	NA
5	101383803	rs12188653	G	C	rs12188653	22310351	0.000143	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced neuropathy in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
5	105031008	rs1904833	A	G	rs1904833	19723657	7.47E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
5	108948937	rs367615	C	T	rs367615	23300701	4.00E-08	rs10795668	1.35	[1.20-1.49]	8,380 European ancestry cases; 10,558 European ancestry controls	European(18938)	ALL(18938)	EUR(18938)	ALL(18938)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
5	114995781	rs6863960	G	A	rs6863960	22310351	0.000227	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced neuropathy in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
5	124055918	rs4623140	C	A	rs4623140	24737748	6.60E-04	NA	1.06	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4623140-A	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	128987225	rs40972	C	T	rs40972	22532847	0.0000211	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer (males)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	ADAMTS19
5	134470030	rs1559050	G	A	rs1559050	21242260	1.28E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
5	134475494	rs11745068	G	T	rs11745068	21242260	1.55E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
5	134485285	rs566750	G	A	rs566750	21242260	9.47E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	134488349	rs3909811	G	T	rs3909811	21242260	1.59E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
5	134499092	rs647161	C	A	rs647161	23263487	1.00E-10	NA	1.11	[1.08-1.15]	2,098 East Asian ancestry cases; 5,749 East Asian ancestry controls	East Asian(7847)	ALL(7847)	ASN(7847)	ALL(7847)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs647161-A	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	134499092	rs647161	C	A	rs647161	23263487	4.00E-10	East Asian	1.17	[1.11-1.22]	2,098 East Asian ancestry cases; 5,749 East Asian ancestry controls	East Asian(7847)	ALL(7847)	ASN(7847)	ALL(7847)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs647161-A	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
5	134499092	rs647161	C	A	rs647161	24836286	2.00E-14	(East Asian)	1.15	[1.11-1.19]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs647161-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
5	154569150	rs1864125	T	C	rs1864125	19723657	8.03E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
5	169923732	rs888934	A	G	rs888934	21242260	2.11E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	171121911	rs10055794	A	G	rs10055794	22310351	0.0000893	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
6	7831972	rs13192135	A	G	rs13192135	22532847	0.00000382	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer (males)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	BMP6
6	16565192	rs9477166	A	G	rs9477166	19723657	6.90E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	G	ATXN1
6	21225577	rs6942273	G	A	rs6942273	21242260	9.52E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	36622900	rs1321311	C	A	rs1321311	22634755	1.00E-10	NA	1.1	[1.07-1.13]	8,323 European ancestry cases; 9,457 European ancestry controls	European(17780)	ALL(17780)	EUR(17780)	ALL(17780)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
6	38505703	rs13219695	A	G	rs13219695	22532847	0.00000814	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	BTBD9
6	39291807	rs1328384	C	A	rs1328384	24737748	3.06E-04	NA	1.06	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1328384-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
6	96333852	rs2799652	A	C	rs2799652	22532847	0.0000235	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	NA
6	117723640	rs9385010	T	C	rs9385010	23266556	4.10E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117724499	rs1407179	A	C	rs1407179	23266556	3.44E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117725578	rs2243378	T	A	rs2243378	23266556	3.96E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117725912	rs1321802	G	C	rs1321802	23266556	4.02E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117726980	rs7770923	C	A	rs7770923	23266556	4.04E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117727025	rs7771211	G	A	rs7771211	23266556	4.03E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117727485	rs7772046	G	A	rs7772046	23266556	4.00E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117727949	rs7776244	C	A	rs7776244	23266556	4.06E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117728118	rs765516	C	T	rs765516	23266556	4.66E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117730592	rs2273602	G	A	rs2273602	23266556	2.71E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117731177	rs1321799	G	T	rs1321799	23266556	3.67E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117731192	rs1321798	A	G	rs1321798	23266556	3.59E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117731968	rs3798393	G	C	rs3798393	23266556	3.35E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117732362	rs3798394	A	T	rs3798394	23266556	3.31E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117732924	rs9401006	T	C	rs9401006	23266556	3.21E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117734746	rs9489152	G	A	rs9489152	23266556	1.63E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117735255	rs3777981	A	C	rs3777981	23266556	2.84E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117777804	rs9374662	G	A	rs9374662	23266556	3.54E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117780158	rs2180811	T	A	rs2180811	23266556	3.19E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117782634	rs9374663	A	G	rs9374663	23266556	3.03E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117785308	rs6937083	A	T	rs6937083	23266556	2.73E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117786180	rs9387478	C	A	rs9387478	23266556	2.75E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117809031	rs6911915	T	C	rs6911915	23266556	6.27E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117815020	rs4945586	T	A	rs4945586	23266556	3.90E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117816045	rs9320604	G	A	rs9320604	23266556	3.92E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117816093	rs4946259	A	G	rs4946259	23266556	1.41E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117817165	rs9481728	C	T	rs9481728	23266556	4.06E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117818911	rs929057	T	A	rs929057	23266556	3.41E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117819357	rs2057314	A	G	rs2057314	23266556	3.00E-06	NA	1.08	[1.04-1.11]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117822993	rs4946260	C	T	rs4946260	23266556	3.44E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	117823508	rs10782186	T	C	rs10782186	23266556	3.53E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
6	129919010	rs10499162	T	C	rs10499162	17618283	7.00E-04	NA	NA	NA	1,257 cases; 1,336 controls	NOPOP(2593)	ALL(2593)	NOPOP(2593)	ALL(2593)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	144869785	rs1534443	A	G	rs1534443	21239504	1.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	UTRN
6	151971687	rs851974	G	A	rs851974	22310351	0.0000937	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced nausea/vomiting in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
6	158435572	rs9365723	A	G	rs9365723	23300701	4.00E-06	(rs6687758, known)	1.27	[1.15-1.41]	8,380 European ancestry cases; 10,558 European ancestry controls	European(18938)	ALL(18938)	EUR(18938)	ALL(18938)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
6	160796058	rs1018234	C	T	rs1018234	21242260	2.00E-04	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	160807432	rs884742	C	A	rs884742	21242260	8.71E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	160833664	rs9364554	C	T	rs9364554	21242260	2.17E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
6	160834828	rs2457571	T	C	rs2457571	21242260	1.91E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
6	160840252	rs7758229	G	T	rs7758229	21242260	8.00E-09	distal colon cancer	1.28	[1.18-1.39]	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs7758229-T	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	160842537	rs3123636	T	C	rs3123636	21242260	2.09E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	160848167	rs2665357	A	C	rs2665357	21242260	1.14E-04	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	160850273	rs3106164	C	T	rs3106164	21242260	6.82E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
7	12053370	rs17165506	A	G	rs17165506	22532847	0.00000341	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer (females)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	NA
7	19820560	rs6953957	A	G	rs6953957	24448986	3.67E-05	NA	1.12	[1.06-1.19]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6953957-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	25133849	rs39453	T	C	rs39453	23300701	2.00E-06	(rs6687758, known)	1.28	[1.16-1.43]	8,380 European ancestry cases; 10,558 European ancestry controls	European(18938)	ALL(18938)	EUR(18938)	ALL(18938)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
7	32422077	rs441261	G	C	rs441261	22532847	0.00000106	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer (females)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	NA
7	33151181	rs3847009	A	G	rs3847009	21242260	1.91E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A,G
7	41821917	rs12701937	C	T	rs12701937	20610541	3.50E-05	Colorectal cancer (familial cases)	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
7	41821956	rs10441105	C	G	rs10441105	20610541	2.20E-05	Colorectal cancer	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
7	47238707	rs1370916	C	T	rs1370916	24743840	2.00E-06	(Red meat)	1.11	[1.06-1.15]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
7	80570142	rs10262428	T	G	rs10262428	21242260	8.97E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
7	84795710	rs2215439	G	A	rs2215439	19723657	5.33E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	C	NA
7	99614313	rs4729566	G	A	rs4729566	21242260	6.83E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
7	125532656	rs2158214	G	T	rs2158214	21242260	5.84E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
7	125537419	rs10238157	G	A	rs10238157	21242260	7.22E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
7	154680910	rs12534701	G	T	rs12534701	24743840	2.00E-06	(Fiber)	1.17	[1.09-1.24]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
8	12772755	rs6989010	G	T	rs6989010	24743840	2.00E-06	(Vegetable)	1.64	NA	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
8	29344462	rs12548021	A	G	rs12548021	23350875	3.00E-06	NA	1.28	[1.16-1.42]	882 European ancestry cases; 473 European ancestry controls	European(1355)	ALL(1355)	EUR(1355)	ALL(1355)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	NA
8	31434385	rs1557800	C	T	rs1557800	19723657	9.13E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	C	NA
8	37161801	rs11785575	G	A	rs11785575	21242260	1.66E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	91175874	rs10106310	C	T	rs10106310	22310351	0.000057	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
8	96595736	rs3104964	G	A	rs3104964	23350875	4.00E-06	NA	1.27	[1.14-1.40]	882 European ancestry cases; 473 European ancestry controls	European(1355)	ALL(1355)	EUR(1355)	ALL(1355)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	LOC100616530
8	117574515	rs140355816	C	G	rs140355816	24737748	2.00E-08	NA	1.59	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs140355816-G	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	117630683	rs16892766	A	C	rs16892766	18372905	3.00E-18	NA	1.27	[1.20-1.34]	922 cases; 927 controls	NOPOP(1849)	ALL(1849)	NOPOP(1849)	ALL(1849)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs16892766-A	Research Support, Non-U.S. Gov't	A	NA
8	117630683	rs16892766	A	C	rs16892766	19011631	1.10E-10	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	117630683	rs16892766	A	C	rs16892766	21761138	4.00E-07	NA	1.24	[1.14-1.34]	2,906 European descent cases; 3,416 European descent controls	European(6322)	ALL(6322)	EUR(6322)	ALL(6322)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis	A
8	117630683	rs16892766	A	C	rs16892766	22532847	0.000000627	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	NA
8	117630683	rs16892766	A	C	rs16892766	22532847	0.0000411	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer (females)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	NA
8	117630683	rs16892766	A	C	rs16892766	23266556	4.59E-10	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	117640315	rs11986063	C	T	rs11986063	19011631	5.70E-10	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	117647788	rs6469656	G	A	rs6469656	24836286	5.00E-08	(East Asian)	1.09	[1.06-1.13]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6469656-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
8	117802148	rs6983626	T	C	rs6983626	19011631	4.40E-06	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	120090827	rs2465403	G	A	rs2465403	22310351	0.000328	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced mucositis in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
8	122660248	rs10089677	G	A	rs10089677	19723657	7.80E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
8	128087904	rs6470494	T	C	rs6470494	17618284	1.27E-04	NA	NA	NA	930 cases; 960 controls	NOPOP(1890)	ALL(1890)	NOPOP(1890)	ALL(1890)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	NA
8	128407443	rs10505477	A	G	rs10505477	17618283	3.00E-11	NA	1.17	[1.12-1.23]	1,257 cases; 1,336 controls	NOPOP(2593)	ALL(2593)	NOPOP(2593)	ALL(2593)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10505477-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
8	128407443	rs10505477	A	G	rs10505477	17618284	3.73E-14	NA	NA	NA	930 cases; 960 controls	NOPOP(1890)	ALL(1890)	NOPOP(1890)	ALL(1890)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	NA
8	128407443	rs10505477	A	G	rs10505477	20610541	5.90E-04	Colorectal cancer	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
8	128407443	rs10505477	A	G	rs10505477	23266556	2.60E-11	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	128407443	rs10505477	A	G	rs10505477	24737748	8.00E-13	NA	1.2	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10505477-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	128407443	rs10505477	A	G	rs10505477	24836286	3.43E-13	(East Asian)	1.15	[1.11-1.20]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10505477-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
8	128409511	rs10808555	G	A	rs10808555	19011631	1.50E-07	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	128413305	rs6983267	G	T	rs6983267	17618283	5.40E-04	NA	NA	NA	1,257 cases; 1,336 controls	NOPOP(2593)	ALL(2593)	NOPOP(2593)	ALL(2593)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
8	128413305	rs6983267	G	T	rs6983267	17618284	1.00E-14	NA	1.27	[1.16-1.39]	930 cases; 960 controls	NOPOP(1890)	ALL(1890)	NOPOP(1890)	ALL(1890)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6983267-G	Research Support, Non-U.S. Gov't	G	NA
8	128413305	rs6983267	G	T	rs6983267	18372905	7.00E-11	NA	1.24	[1.17-1.33]	922 cases; 927 controls	NOPOP(1849)	ALL(1849)	NOPOP(1849)	ALL(1849)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	NA
8	128413305	rs6983267	G	T	rs6983267	19011631	2.10E-14	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	128413305	rs6983267	G	T	rs6983267	20610541	7.00E-04	Colorectal cancer	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
8	128413305	rs6983267	G	T	rs6983267	21242260	2.00E-08	colorectal cancer	1.18	[1.11-1.25]	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6983267-G	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	128413305	rs6983267	G	T	rs6983267	23266556	1.00E-11	NA	1.13	[1.09-1.18]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6983267-G	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	128413305	rs6983267	G	T	rs6983267	24836286	5.00E-14	(East Asian)	1.14	[1.10-1.18]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6983267-G	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
8	128423127	rs7837328	A	G	rs7837328	17618284	3.00E-04	NA	NA	NA	930 cases; 960 controls	NOPOP(1890)	ALL(1890)	NOPOP(1890)	ALL(1890)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	NA
8	128423127	rs7837328	A	G	rs7837328	19011631	1.20E-10	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	128423127	rs7837328	A	G	rs7837328	21242260	2.13E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	128423817	rs10956369	T	A	rs10956369	20610541	4.20E-05	Colorectal cancer	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
8	128424792	rs7014346	A	G	rs7014346	17618284	2.00E-04	NA	NA	NA	930 cases; 960 controls	NOPOP(1890)	ALL(1890)	NOPOP(1890)	ALL(1890)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	NA
8	128424792	rs7014346	A	G	rs7014346	18372901	9.00E-26	NA	1.19	[1.15-1.23]	981 cases; 1,002 controls	NOPOP(1983)	ALL(1983)	NOPOP(1983)	ALL(1983)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs7014346-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
8	128424792	rs7014346	A	G	rs7014346	19011631	3.00E-13	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
8	128424792	rs7014346	A	G	rs7014346	20610541	2.50E-04	Colorectal cancer	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
8	128424792	rs7014346	A	G	rs7014346	23266556	2.52E-10	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	128424792	rs7014346	A	G	rs7014346	24836286	1.96E-08	(East Asian)	1.13	[1.08-1.17]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs7014346-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
8	128453928	rs12334695	T	C	rs12334695	17618284	6.00E-04	NA	NA	NA	930 cases; 960 controls	NOPOP(1890)	ALL(1890)	NOPOP(1890)	ALL(1890)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	NA
8	128466814	rs7841264	C	T	rs7841264	17618284	2.00E-04	NA	NA	NA	930 cases; 960 controls	NOPOP(1890)	ALL(1890)	NOPOP(1890)	ALL(1890)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	LOC727677
8	130818030	rs17276203	G	C	rs17276203	23266556	3.32E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130818636	rs7014175	C	G	rs7014175	23266556	3.32E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130820039	rs2128382	C	T	rs2128382	23266556	8.00E-06	NA	1.11	[1.06-1.16]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130820375	rs2170568	T	A	rs2170568	23266556	9.20E-07	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130820635	rs2128383	A	G	rs2128383	23266556	9.61E-07	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130821049	rs2894493	C	T	rs2894493	23266556	1.21E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130822194	rs7006896	G	A	rs7006896	23266556	1.00E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130837943	rs10109713	T	C	rs10109713	23266556	2.46E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130868061	rs2306528	G	T	rs2306528	23266556	3.66E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130880015	rs10956502	T	G	rs10956502	23266556	1.58E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130882869	rs16904166	C	T	rs16904166	23266556	1.58E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130885528	rs4395866	A	G	rs4395866	23266556	1.55E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	130901909	rs2086641	T	C	rs2086641	23266556	1.00E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
8	134098665	rs2739171	G	A	rs2739171	22310351	0.000104	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced nausea/vomiting in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
8	138514170	rs1399176	T	C	rs1399176	17618283	7.00E-04	NA	NA	NA	1,257 cases; 1,336 controls	NOPOP(2593)	ALL(2593)	NOPOP(2593)	ALL(2593)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
9	5719116	rs10975258	C	A	rs10975258	21242260	1.18E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
9	5747187	rs10815278	C	T	rs10815278	24448986	5.97E-04	NA	1.1	[1.04-1.16]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10815278-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
9	6365683	rs719725	A	C	rs719725	17618283	1.32E-05	NA	NA	NA	1,257 cases; 1,336 controls	NOPOP(2593)	ALL(2593)	NOPOP(2593)	ALL(2593)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
9	17100003	rs13289535	A	G	rs13289535	24448986	3.65E-05	NA	1.28	[1.14-1.45]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs13289535-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
9	22125347	rs1333048	A	C	rs1333048	24836286	3.00E-04	(East Asian)	1.06	[1.03-1.09]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1333048-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
9	25286650	rs10511753	G	A	rs10511753	21242260	2.33E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
9	30979640	rs2888998	A	G	rs2888998	19723657	7.91E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
9	32886639	rs1888871	G	A	rs1888871	21242260	9.88E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
9	73448055	rs2275242	C	T	rs2275242	21242260	4.30E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
9	73452287	rs2039645	G	A	rs2039645	21242260	3.52E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
9	83169355	rs2209907	A	G	rs2209907	20610541	3.40E-08	Colorectal cancer	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
9	94408117	rs10992029	A	C	rs10992029	24448986	1.09E-04	NA	1.12	[1.05-1.19]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10992029-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	96631134	rs10114408	A	T	rs10114408	23300701	3.00E-06	(rs4779584, known)	1.37	[1.20-1.56]	8,380 European ancestry cases; 10,558 European ancestry controls	European(18938)	ALL(18938)	EUR(18938)	ALL(18938)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
9	117166246	rs2274159	A	G	rs2274159	21239504	7.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G,C	DFNB31
9	117169033	rs942519	A	G	rs942519	21239504	7.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G,C	DFNB31
9	117792583	rs13321	C	G	rs13321	21239504	2.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	TNC
9	117808785	rs2104772	T	A	rs2104772	21239504	2.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	TNC
9	121788712	rs724975	G	A	rs724975	22310351	0.000135	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced nausea/vomiting in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
9	126951284	rs7042608	G	A	rs7042608	21242260	1.80E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
9	137595928	rs4240703	A	G	rs4240703	21242260	2.21E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
9	137596166	rs3935335	G	A	rs3935335	21242260	1.85E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C,T
9	137601285	rs4841926	C	T	rs4841926	21242260	7.07E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
9	137602119	rs3128591	G	A	rs3128591	21242260	1.45E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
10	8089136	rs4143094	T	G	rs4143094	24743840	9.00E-09	(Processed meat)	1.17	[1.11-1.23]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	rs4143094-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
10	8093185	rs485411	T	C	rs485411	24743840	1.72E-08	(Processed meat)	1.18	[1.11-1.25]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
10	8096199	rs1269486	A	G	rs1269486	24743840	7.53E-08	(Processed meat)	1.18	[1.11-1.25]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
10	8701219	rs10795668	G	A	rs10795668	18372905	3.00E-13	NA	1.12	[1.10-1.16]	922 cases; 927 controls	NOPOP(1849)	ALL(1849)	NOPOP(1849)	ALL(1849)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10795668-A	Research Support, Non-U.S. Gov't	G	NA
10	8701219	rs10795668	G	A	rs10795668	24836286	5.00E-15	(East Asian)	1.15	[1.11-1.19]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10795668-G	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
10	8739580	rs11255841	T	A	rs11255841	24737748	7.00E-11	NA	1.19	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs11255841-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
10	14119720	rs3101357	G	T	rs3101357	21242260	2.71E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
10	14123459	rs2614143	G	A	rs2614143	21242260	4.39E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A,G
10	14872427	rs7094179	C	A	rs7094179	22310351	0.000371	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced nausea/vomiting in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
10	16719088	rs12572686	A	G	rs12572686	19723657	5.08E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	RSU1
10	26483183	rs11014993	T	C	rs11014993	20610541	2.70E-04	Colorectal cancer (familial cases)	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
10	26778606	rs12412826	G	A	rs12412826	21242260	2.04E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
10	29505124	rs887339	T	C	rs887339	22310351	0.0000108	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced diarrhoea in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
10	31655768	rs2839657	C	T	rs2839657	19723657	5.23E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	T	ZEB1
10	55371601	rs10825073	C	T	rs10825073	21242260	1.13E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
10	55371788	rs6481026	G	A	rs6481026	21242260	1.22E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
10	55385962	rs7095328	C	T	rs7095328	21242260	8.80E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
10	55389030	rs9416286	T	C	rs9416286	21242260	2.34E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
10	55391609	rs7906396	T	C	rs7906396	21242260	1.90E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
10	55394615	rs11003722	A	G	rs11003722	21242260	2.82E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
10	55395318	rs7078645	G	A	rs7078645	21242260	1.70E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
10	55395380	rs7097226	A	C	rs7097226	21242260	1.36E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
10	55418087	rs11003740	C	A	rs11003740	21242260	2.26E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
10	60571435	rs4948317	C	T	rs4948317	24836286	7.00E-08	(East Asian)	1.1	[1.06-1.13]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4948317-C	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
10	64024648	rs7923556	A	G	rs7923556	24448986	2.10E-07	NA	1.37	[1.22-1.54]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs7923556-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
10	69926334	rs10823148	C	G	rs10823148	21239504	2.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	MYPN
10	69933969	rs7916821	G	A	rs7916821	21239504	2.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	MYPN
10	69959242	rs7079481	C	A	rs7079481	21239504	2.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	MYPN
10	80819132	rs704017	A	G	rs704017	24836286	2.00E-08	(East Asian)	1.1	[1.06-1.13]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs704017-G	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
10	81926702	rs1049550	G	A	rs1049550	21239504	9.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	ANXA11
10	101288935	rs12412391	A	G	rs12412391	24836286	7.00E-07	(East Asian)	1.08	[1.05-1.11]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs12412391-G	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
10	101345366	rs1035209	C	T	rs1035209	24737748	5.00E-11	NA	1.12	[1.08-1.16]	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1035209-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
10	114726843	rs11196172	G	A	rs11196172	24836286	1.00E-12	(East Asian)	1.14	[1.10-1.18]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs11196172-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
10	118487100	rs1665650	T	C	rs1665650	23263487	9.00E-07	East Asian	1.13	[1.08-1.19]	2,098 East Asian ancestry cases; 5,749 East Asian ancestry controls	East Asian(7847)	ALL(7847)	ASN(7847)	ALL(7847)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1665650-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	256714	rs879872	C	T	rs879872	22532847	1.14E-11	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	NA
11	4830652	rs1865282	T	G	rs1865282	22310351	0.0000149	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced diarrhea in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
11	17784707	rs17718902	G	A	rs17718902	22310351	0.000179	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced neuropathy in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
11	18311701	rs11024605	T	C	rs11024605	24737748	2.64E-04	NA	1.11	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs11024605-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	33601647	rs4755201	C	T	rs4755201	19723657	7.31E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	C	C11orf41
11	33602913	rs4755718	G	A	rs4755718	19723657	7.32E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	G	C11orf41
11	61552680	rs174537	G	T	rs174537	24836286	9.00E-21	(East Asian)	1.16	[1.12-1.19]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs174537-G	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
11	61564299	rs4246215	G	T	rs4246215	24836286	7.65E-20	(East Asian)	1.15	[1.12-1.19]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4246215-G	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
11	61571478	rs174550	T	C	rs174550	24836286	1.58E-19	(East Asian)	1.15	[1.12-1.19]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs174550-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
11	61597972	rs1535	A	G	rs1535	24836286	8.21E-20	(East Asian)	1.15	[1.12-1.19]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1535-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
11	74345550	rs3824999	T	G	rs3824999	22634755	4.00E-10	NA	1.08	[1.05-1.10]	8,323 European ancestry cases; 9,457 European ancestry controls	European(17780)	ALL(17780)	EUR(17780)	ALL(17780)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	74345550	rs3824999	T	G	rs3824999	23266556	3.43E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
11	86053419	rs10792847	A	G	rs10792847	21242260	1.09E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G,A
11	100137346	rs1348271	T	G	rs1348271	19723657	6.43E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	T	CNTN5
11	106656863	rs901779	A	G	rs901779	21242260	1.77E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
11	111135745	rs11213809	A	G	rs11213809	19011631	2.40E-12	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	111166504	rs12296076	G	A	rs12296076	20610541	1.80E-06	Colorectal cancer	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
11	111171709	rs3802842	C	A	rs3802842	18372901	6.00E-10	NA	1.11	[1.08-1.15]	981 cases; 1,002 controls	NOPOP(1983)	ALL(1983)	NOPOP(1983)	ALL(1983)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs3802842-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
11	111171709	rs3802842	C	A	rs3802842	19011631	5.20E-13	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	111171709	rs3802842	C	A	rs3802842	21761138	4.00E-07	NA	1.14	[1.08-1.20]	2,906 European descent cases; 3,416 European descent controls	European(6322)	ALL(6322)	EUR(6322)	ALL(6322)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis	C
11	111171709	rs3802842	C	A	rs3802842	23266556	4.00E-07	NA	1.11	[1.06-1.15]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
11	111171709	rs3802842	C	A	rs3802842	24836286	3.00E-07	(East Asian)	1.09	[1.05-1.12]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs3802842-C	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
11	111189158	rs10749971	A	G	rs10749971	19011631	8.00E-07	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
11	111352032	rs1944118	G	A	rs1944118	22310351	0.0000127	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced neuropathy in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
11	121452651	rs11218350	T	A	rs11218350	24978480	1.79E-04	NA	1.28	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs11218350-T	Research Support, Non-U.S. Gov't	T	SORL1
12	975948	rs12309274	T	G	rs12309274	24836286	3.00E-06	(East Asian)	1.11	[1.06-1.16]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs12309274-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
12	4368352	rs10774214	T	C	rs10774214	23263487	3.00E-08	NA	1.09	[1.06-1.13]	2,098 East Asian ancestry cases; 5,749 East Asian ancestry controls	East Asian(7847)	ALL(7847)	ASN(7847)	ALL(7847)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10774214-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
12	4368352	rs10774214	T	C	rs10774214	23263487	5.00E-10	East Asian	1.17	[1.11-1.23]	2,098 East Asian ancestry cases; 5,749 East Asian ancestry controls	East Asian(7847)	ALL(7847)	ASN(7847)	ALL(7847)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10774214-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
12	4368352	rs10774214	T	C	rs10774214	24836286	1.00E-10	(East Asian)	1.14	[1.09-1.18]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10774214-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
12	4388271	rs3217810	C	T	rs3217810	23266556	6.00E-08	NA	1.2	[1.12-1.28]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs3217810-T	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	4392391	rs3217827	C	A	rs3217827	23266556	2.50E-07	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	4402688	rs3217881	A	G	rs3217881	23266556	3.79E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	4402817	rs3217882	A	G	rs3217882	23266556	3.29E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	4405389	rs3217901	A	G	rs3217901	23266556	3.00E-07	NA	1.1	[1.06-1.14]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs3217901-G	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	4910812	rs1860345	T	C	rs1860345	19723657	1.85E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	C	NA
12	6385727	rs10849432	C	T	rs10849432	24836286	6.00E-10	(East Asian)	1.14	[1.09-1.18]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10849432-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
12	28758634	rs1996041	A	G	rs1996041	21242260	5.28E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
12	28794063	rs10450689	C	T	rs10450689	21242260	2.29E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
12	50573433	rs34245511	G	C	rs34245511	24737748	3.00E-08	NA	1.14	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs34245511-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
12	50880216	rs7136702	T	C	rs7136702	23266556	5.83E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	51155663	rs11169552	C	T	rs11169552	20972440	2.00E-10	NA	1.09	[1.05-1.11]	3,334 European ancestry cases; 4,628 European ancestry controls	European(7962)	ALL(7962)	EUR(7962)	ALL(7962)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs11169552-C	Research Support, Non-U.S. Gov't	C	NA
12	56050706	rs10876844	C	A	rs10876844	22310351	0.0000478	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced diarrhoea in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
12	57331741	rs725957	G	A	rs725957	24836286	8.19E-05	(East Asian)	1.06	[1.03-1.09]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs725957-G	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
12	68708761	rs2306393	C	T	rs2306393	21239504	3.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	MDM1
12	68720627	rs962976	G	A	rs962976	21239504	3.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	MDM1
12	69422029	rs10784749	C	G	rs10784749	22310351	0.000117	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced diarrhoea in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
12	72414563	rs10879357	A	G	rs10879357	23300701	3.00E-06	(rs1571218, novel)	1.25	[1.14-1.39]	8,380 European ancestry cases; 10,558 European ancestry controls	European(18938)	ALL(18938)	EUR(18938)	ALL(18938)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Research Support, N.I.H., Intramural
12	73243456	rs7313919	C	T	rs7313919	24448986	1.21E-04	NA	1.13	[1.06-1.20]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs7313919-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	90566978	rs1347851	C	T	rs1347851	22310351	0.0000423	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced diarrhea in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
12	96880242	rs3858655	C	A	rs3858655	24978480	1.47E-04	NA	1.34	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs3858655-T	Research Support, Non-U.S. Gov't	C	NA
12	96918529	rs17375557	C	T	rs17375557	24978480	1.75E-04	NA	1.33	NA	480 European ancestry cases; 801 European ancestry controls	European(1281)	ALL(1281)	EUR(1281)	ALL(1281)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs17375557-A	Research Support, Non-U.S. Gov't	C	C12orf55
12	114488668	rs7958635	C	T	rs7958635	19723657	5.31E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	T	NA
12	115094260	rs11067228	A	G	rs11067228	23266556	6.72E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	115114036	rs551510	C	T	rs551510	23266556	9.42E-07	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	115116352	rs59336	T	A	rs59336	23266556	4.00E-07	NA	1.09	[1.06-1.13]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs59336-T	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	115118997	rs515746	G	A	rs515746	23266556	9.61E-07	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	115119903	rs545076	G	A	rs545076	23266556	6.73E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
12	115891403	rs7315438	C	T	rs7315438	21761138	6.00E-06	NA	1.11	[1.06-1.15]	2,906 European descent cases; 3,416 European descent controls	European(6322)	ALL(6322)	EUR(6322)	ALL(6322)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis	T
12	116041955	rs11835096	A	G	rs11835096	21242260	2.04E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	24808704	rs927553	C	G	rs927553	22310351	0.000305	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced mucositis in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
13	40818284	rs7325568	C	T	rs7325568	22310351	0.0000661	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil and oxaliplatin combined induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
13	40818284	rs7325568	C	T	rs7325568	22310351	0.0000661	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
13	42597284	rs17062732	A	G	rs17062732	19723657	5.90E-06	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	G	NA
13	48369730	rs7999699	A	G	rs7999699	24743840	3.00E-06	(Fruit)	1.32	[1.18-1.47]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
13	73691236	rs1333099	G	A	rs1333099	24737748	1.28E-05	NA	1.07	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1333099-A	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
13	73989158	rs4144229	A	T	rs4144229	24836286	5.57E-05	(East Asian)	1.07	[1.04-1.11]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4144229-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
13	79128568	rs1325619	A	G	rs1325619	19723657	9.45E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
13	98478535	rs7988900	T	C	rs7988900	21242260	2.71E-07	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	103449202	rs1047740	T	C	rs1047740	21239504	2.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	KDELC1
13	104036311	rs9300811	T	C	rs9300811	22310351	0.000501	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced nausea/vomiting in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
14	24128135	rs12590792	G	T	rs12590792	24448986	1.03E-04	NA	1.13	[1.06-1.20]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs12590792-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	39019800	rs11847817	T	C	rs11847817	21242260	3.28E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
14	39053121	rs2415493	A	G	rs2415493	21242260	1.99E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	46921265	rs12434073	G	A	rs12434073	21242260	2.03E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
14	46984498	rs2600814	T	C	rs2600814	21242260	1.72E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	47503489	rs1539213	A	G	rs1539213	24448986	3.62E-05	NA	1.12	[1.06-1.19]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1539213-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
14	54410919	rs4444235	T	C	rs4444235	19011631	8.00E-10	NA	1.11	[1.08-1.15]	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4444235-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
14	54419106	rs35107139	A	C	rs35107139	24737748	1.39E-04	NA	1.1	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs35107139-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
14	59183198	rs17094971	A	T	rs17094971	23266556	9.35E-07	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59184529	rs7141538	C	T	rs7141538	23266556	9.41E-07	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59185056	rs1432096	G	T	rs1432096	23266556	8.92E-07	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59189361	rs17094983	G	A	rs17094983	23266556	3.00E-06	NA	1.13	[1.08-1.20]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59210335	rs710007	G	A	rs710007	23266556	6.02E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59210489	rs856380	T	G	rs856380	23266556	7.44E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59210646	rs856379	A	G	rs856379	23266556	7.15E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59210881	rs856378	G	A	rs856378	23266556	4.03E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59210944	rs856377	T	C	rs856377	23266556	6.44E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59210957	rs856376	G	A	rs856376	23266556	4.93E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59211420	rs710005	T	C	rs710005	23266556	5.26E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59211557	rs856375	T	G	rs856375	23266556	6.25E-06	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59224735	rs377425	T	C	rs377425	23266556	3.72E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59226554	rs385902	T	G	rs385902	23266556	3.94E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59233594	rs856204	T	G	rs856204	23266556	5.83E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59236137	rs856208	G	C	rs856208	23266556	5.89E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59236388	rs856209	T	C	rs856209	23266556	5.96E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	59239852	rs856213	A	G	rs856213	23266556	6.59E-04	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
14	83051150	rs2798389	C	T	rs2798389	22310351	0.0000929	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
14	86133451	rs8008317	A	G	rs8008317	19723657	5.27E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
14	90745422	rs3737035	T	C	rs3737035	21239504	5.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	C14orf102
14	91739081	rs941920	A	G	rs941920	21239504	2.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	CCDC88C
14	97849962	rs234460	A	G	rs234460	21242260	1.23E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
14	100104329	rs17098912	G	A	rs17098912	22310351	0.000248	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced mucositis in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
14	104464809	rs10142229	C	T	rs10142229	21242260	2.45E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
15	26282791	rs4243761	G	T	rs4243761	22310351	0.0000513	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil and oxaliplatin combined induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
15	26282791	rs4243761	G	T	rs4243761	22310351	0.0000513	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
15	32994756	rs4779584	T	C	rs4779584	18372905	5.00E-07		1.23	[1.14-1.34]	922 cases; 927 controls	NOPOP(1849)	ALL(1849)	NOPOP(1849)	ALL(1849)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	NA
15	32994756	rs4779584	T	C	rs4779584	19011631	1.70E-08	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
15	32994756	rs4779584	T	C	rs4779584	21761138	2.00E-08	NA	1.18	[1.11-1.24]	2,906 European descent cases; 3,416 European descent controls	European(6322)	ALL(6322)	EUR(6322)	ALL(6322)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis	C
15	32994756	rs4779584	T	C	rs4779584	23266556	5.00E-07	NA	1.12	[1.08-1.19]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
15	33012502	rs73376930	A	G	rs73376930	24737748	1.00E-11	NA	1.25	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs73376930-G	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
15	33025979	rs10318	C	T	rs10318	19011631	1.20E-07	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
15	67026217	rs2053423	C	T	rs2053423	24737748	5.86E-05	NA	1.08	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2053423-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
15	81029628	rs7171423	T	C	rs7171423	22532847	0.000036	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	FAM108C1
15	90764219	rs4932305	G	A	rs4932305	21239504	1.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	SEMA4B
15	92859881	rs1871438	A	G	rs1871438	24743840	8.00E-07	(Red meat)	1.11	[1.07-1.16]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
15	93015427	rs1455773	G	A	rs1455773	21239504	7.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	C15orf32
15	93908402	rs11636893	C	A	rs11636893	19723657	8.95E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	C	NA
15	101109677	rs8451	C	A	rs8451	21239504	5.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	G	LINS
15	101109794	rs12157	C	G	rs12157	21239504	5.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	LINS
15	101110302	rs2411837	C	G	rs2411837	21239504	5.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	LINS
15	101120963	rs11247226	T	C	rs11247226	21239504	5.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	A	LINS
15	101547631	rs11247251	C	T	rs11247251	24737748	1.38E-04	NA	1.12	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs11247251-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
16	17659635	rs11075365	A	G	rs11075365	19723657	7.06E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	G	NA
16	25263278	rs2112811	G	A	rs2112811	21239504	9.53E-05	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	ZKSCAN2
16	49051381	rs2908866	T	C	rs2908866	21242260	1.41E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
16	51903470	rs11076194	A	G	rs11076194	19723657	4.66E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
16	65902950	rs17697705	G	A	rs17697705	21242260	1.14E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
16	68820946	rs9929218	G	A	rs9929218	19011631	1.00E-08	NA	1.1	[1.06-1.12]	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs9929218-G	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
16	68832943	rs1862748	C	T	rs1862748	19011631	2.60E-06	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
16	69104267	rs143939627	G	A	rs143939627	24737748	2.61E-05	NA	1.31	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs143939627-A	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
16	73811879	rs1849240	T	C	rs1849240	24448986	6.30E-05	NA	1.15	[1.08-1.24]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1849240-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
16	78860946	rs7184580	A	C	rs7184580	22310351	0.000114	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
17	800593	rs12603526	T	C	rs12603526	24836286	3.00E-08	(East Asian)	1.1	[1.06-1.14]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs12603526-C	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
17	4508276	rs4790657	T	G	rs4790657	21242260	1.57E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
17	7536527	rs6259	G	A	rs6259	24836286	1.06E-04	(East Asian)	1.09	[1.04-1.14]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs6259-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
17	7545721	rs1641537	T	C	rs1641537	24836286	4.34E-04	(East Asian)	1.07	[1.03-1.11]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1641537-C	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
17	10709753	rs17817050	A	G	rs17817050	24836286	1.10E-05	(East Asian)	1.13	[1.07-1.19]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs17817050-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
17	26742060	rs11080058	G	A	rs11080058	22310351	0.000222	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced neuropathy in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
17	64738297	rs3803820	A	G	rs3803820	22532847	0.000236	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	PRKCA
17	75247279	rs2174919	G	A	rs2174919	21242260	1.65E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
18	8692920	rs670454	T	C	rs670454	22310351	0.0007	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced mucositis in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
18	40334100	rs618236	T	G	rs618236	19723657	6.34E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	RIT2
18	46450976	rs7229639	A	G	rs7229639	24448986	3.00E-11	NA	1.22	[1.15-1.29]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs7229639-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
18	46450976	rs7229639	A	G	rs7229639	24836286	2.00E-08	(East Asian)	1.2	[1.16-1.25]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs7229639-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
18	46453463	rs4939827	T	C	rs4939827	17934461	1.00E-12	NA	1.16	[1.09-1.27]	940 cases; 965 controls	NOPOP(1905)	ALL(1905)	NOPOP(1905)	ALL(1905)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4939827-T	Research Support, Non-U.S. Gov't	Comparative Study	T
18	46453463	rs4939827	T	C	rs4939827	18372901	8.00E-28	NA	1.2	[1.16-1.24]	981 cases; 1,002 controls	NOPOP(1983)	ALL(1983)	NOPOP(1983)	ALL(1983)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4939827-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
18	46453463	rs4939827	T	C	rs4939827	18372905	2.00E-06		1.18	[1.10-1.25]	922 cases; 927 controls	NOPOP(1849)	ALL(1849)	NOPOP(1849)	ALL(1849)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	SMAD7
18	46453463	rs4939827	T	C	rs4939827	19011631	2.20E-11	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
18	46453463	rs4939827	T	C	rs4939827	21761138	1.00E-07	NA	1.14	[1.08-1.18]	2,906 European descent cases; 3,416 European descent controls	European(6322)	ALL(6322)	EUR(6322)	ALL(6322)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis	T
18	46453463	rs4939827	T	C	rs4939827	23266556	2.00E-10	NA	1.12	[1.09-1.16]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
18	46453463	rs4939827	T	C	rs4939827	24836286	1.53E-08	(East Asian)	1.12	[1.08-1.16]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4939827-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
18	46453929	rs12953717	C	T	rs12953717	17934461	9.10E-12	NA	NA	NA	940 cases; 965 controls	NOPOP(1905)	ALL(1905)	NOPOP(1905)	ALL(1905)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	Comparative Study	C
18	46453929	rs12953717	C	T	rs12953717	19011631	4.70E-12	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
18	46459032	rs4464148	T	C	rs4464148	17934461	3.94E-08	NA	NA	NA	940 cases; 965 controls	NOPOP(1905)	ALL(1905)	NOPOP(1905)	ALL(1905)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	Comparative Study	C
18	57490324	rs1943423	G	A	rs1943423	22310351	0.000251	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
18	69743289	rs10514036	A	G	rs10514036	21242260	2.48E-05	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
19	21804968	rs7255865	A	G	rs7255865	22310351	0.000178	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced mucositis in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
19	22794686	rs11671104	A	C	rs11671104	24743840	4.00E-06	(Fruit)	1.25	[1.13-1.37]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
19	28711798	rs4806074	T	C	rs4806074	19723657	1.00E-04	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	T	NA
19	28734078	rs1840819	A	C	rs1840819	19723657	7.37E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
19	30920536	rs7247381	T	C	rs7247381	24448986	2.39E-05	NA	1.15	[1.08-1.22]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs7247381-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
19	33527888	rs13343954	T	C	rs13343954	24737748	7.00E-08	NA	1.18	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs13343954-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
19	33532300	rs10411210	C	T	rs10411210	19011631	5.00E-09	NA	1.15	[1.10-1.20]	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10411210-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
19	33532300	rs10411210	C	T	rs10411210	24836286	3.00E-06	(East Asian)	1.12	[1.07-1.17]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs10411210-C	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
19	33534641	rs7259371	G	A	rs7259371	19011631	5.70E-06	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
19	34556297	rs4805974	G	A	rs4805974	22310351	0.000136	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced haematologic in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
19	41854086	rs2241716	C	T	rs2241716	24836286	1.86E-07	(East Asian)	1.09	[1.05-1.12]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2241716-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
19	41860296	rs1800469	A	G	rs1800469	24836286	1.00E-08	(East Asian)	1.09	[1.06-1.12]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1800469-G	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
19	41869392	rs2241714	T	C	rs2241714	24836286	1.36E-08	(East Asian)	1.09	[1.06-1.12]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2241714-C	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
19	46974003	rs7248888	C	T	rs7248888	24743840	5.00E-06	(Fruit)	1.37	[1.19-1.56]	9,287 European ancestry cases; 9,117 European ancestry controls	European(18404)	ALL(18404)	EUR(18404)	ALL(18404)	Colorectal cancer (diet interaction)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Research Support, Non-U.S. Gov't
19	54851228	rs8102662	A	G	rs8102662	19723657	4.33E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A,G	LILRA4
20	565077	rs6038071	C	T	rs6038071	20610541	3.00E-04	Colorectal cancer (familial cases)	NA	NA	371 German cases; 1263 German controls	German(1634)	ALL(1634)	EUR(1634)	ALL(1634)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	Comparative Study
20	6380344	rs34033947	T	A	rs57046232	24737748	3.00E-06	NA	1.11	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs57046232-T	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
20	6388068	rs355527	T	C	rs355527	19011631	1.20E-06	NA	NA	NA	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
20	6404281	rs961253	C	A	rs961253	19011631	2.00E-10	NA	1.12	[1.08-1.16]	1,902 cases; 1,929 controls	NOPOP(3831)	ALL(3831)	NOPOP(3831)	ALL(3831)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs961253-A	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
20	6404281	rs961253	C	A	rs961253	21761138	5.16E-05	NA	NA	NA	2,906 European descent cases; 3,416 European descent controls	European(6322)	ALL(6322)	EUR(6322)	ALL(6322)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis	A
20	6404281	rs961253	C	A	rs961253	23266556	3.67E-05	NA	NA	NA	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Review	Research Support, N.I.H., Extramural	Meta-Analysis
20	6404281	rs961253	C	A	rs961253	24836286	7.74E-04	(East Asian)	1.1	[1.04-1.17]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs961253-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
20	6699595	rs4813802	T	G	rs4813802	23266556	7.00E-06	NA	1.1	[1.05-1.14]	12,696 European ancestry colorectal tumor cases; and 15,113 European ancestry controls	European(27809)	ALL(27809)	EUR(27809)	ALL(27809)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4813802-G	Review	Research Support, N.I.H., Extramural	Meta-Analysis
20	6699595	rs4813802	T	G	rs4813802	24737748	9.89E-06	NA	1.14	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4813802-G	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
20	6699595	rs4813802	T	G	rs4813802	24836286	9.87E-06	(East Asian)	1.12	[1.06-1.17]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4813802-G	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
20	7812350	rs2423279	T	C	rs2423279	23263487	2.00E-07	East Asian	1.14	[1.08-1.19]	2,098 East Asian ancestry cases; 5,749 East Asian ancestry controls	East Asian(7847)	ALL(7847)	ASN(7847)	ALL(7847)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2423279-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
20	7812350	rs2423279	T	C	rs2423279	23263487	7.00E-09	NA	1.1	[1.06-1.14]	2,098 East Asian ancestry cases; 5,749 East Asian ancestry controls	East Asian(7847)	ALL(7847)	ASN(7847)	ALL(7847)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2423279-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
20	7812350	rs2423279	T	C	rs2423279	24836286	3.00E-12	(East Asian)	1.13	[1.09-1.17]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2423279-C	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
20	8968642	rs4813881	A	T	rs4813881	22310351	0.0000785	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	5-fluorouracil induced diarrhoea in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
20	10614435	rs2143619	A	G	rs2143619	24448986	9.08E-06	NA	1.14	[1.08-1.20]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2143619-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
20	40609084	rs6029910	C	T	rs6029910	19723657	2.09E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	T	NA
20	40683594	rs1884033	G	A	rs1884033	19723657	2.51E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
20	40706494	rs1884040	C	T	rs1884040	19723657	5.80E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	T	PTPRT
20	47033829	rs6012416	G	A	rs6012416	19723657	4.45E-05	Colorectal cancer	NA	NA	921 European ancestry cases; 929 European ancestry controls	European(1850)	ALL(1850)	EUR(1850)	ALL(1850)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	NA	A	NA
20	60921044	rs4925386	T	C	rs4925386	20972440	2.00E-10	NA	1.08	[1.05-1.10]	3,334 European ancestry cases; 4,628 European ancestry controls	European(7962)	ALL(7962)	EUR(7962)	ALL(7962)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs4925386-C	Research Support, Non-U.S. Gov't	C	LAMA5
20	60969451	rs2427308	C	T	rs2427308	24737748	3.00E-11	NA	1.24	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2427308-C	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
21	16351448	rs909388	A	C	rs909388	24836286	6.67E-05	(East Asian)	1.06	[1.03-1.09]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs909388-A	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
21	26769507	rs1547233	T	C	rs1547233	24448986	4.03E-04	NA	1.12	[1.05-1.19]	1,773 East Asian ancestry cases; 2,642 East Asian ancestry controls	East Asian(4415)	ALL(4415)	ASN(4415)	ALL(4415)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs1547233-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
21	35229419	rs2282469	T	C	rs2282469	22310351	0.0000382	NA	NA	NA	203 European ancestry cases	European(203)	ALL(203)	EUR(203)	ALL(203)	Oxaliplatin induced diarrhea in response to colorectal cancer treatment	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
21	47773177	rs2249060	C	T	rs2249060	24836286	8.73E-05	(East Asian)	1.07	[1.04-1.11]	2,098 East Asian ancestry cases; 6,172 East Asian ancestry controls	East Asian(8270)	ALL(8270)	ASN(8270)	ALL(8270)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2249060-T	Research Support, N.I.H., Extramural	Research Support, U.S. Gov't, P.H.S.	Meta-Analysis
22	34219939	rs2267296	A	G	rs2267296	24737748	5.92E-04	NA	1.05	NA	5,626 European ancestry cases; 7,817 European ancestry controls	European(13443)	ALL(13443)	EUR(13443)	ALL(13443)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	rs2267296-A	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
22	35463162	rs361863	A	G	rs361863	21239504	9.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Cetuximab+5-FU/leucovorin+irinotecan regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	ISX
22	43640728	rs5759225	A	G	rs5759225	21242260	8.43E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
22	46913774	rs4823839	T	C	rs4823839	21242260	7.97E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
22	46916280	rs17589429	T	C	rs17589429	21242260	7.07E-06	NA	NA	NA	1,583 Japanese cases; 1,898 Japanese controls	Japanese(3481)	ALL(3481)	ASN(3481)	ALL(3481)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
X	7686400	rs12689028	T	C	rs12689028	22532847	1.19E-08	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	NA
X	9751474	rs5934683	T	C	rs5934683	22634755	7.00E-10	NA	1.07	[1.04-1.10]	8,323 European ancestry cases; 9,457 European ancestry controls	European(17780)	ALL(17780)	EUR(17780)	ALL(17780)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, N.I.H., Extramural	Meta-Analysis	Research Support, Non-U.S. Gov't
X	11434093	rs5978435	T	C	rs5978435	22532847	0.00000916	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer (males)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	ARHGAP6
X	55289720	rs2296807	C	A,G,T	rs2296807	21239504	2.00E-04	Chemosensitivity to targeted regimes in metastatic colorectal cancer (Bevacizumab+5-FU/leucovorin+oxaliplatin regime)	NA	NA	216 Korean cancer cases; 460 Korean controls	Korean(676)	ALL(676)	ASN(676)	ALL(676)	Colorectal cancer (drug response in metastatic colorectal cancer)	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	NA	NA	NA	NA	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	C	NA
X	57010138	rs912956	C	T	rs912956	22532847	0.000000193	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	SPIN3
X	102807182	rs5987543	T	C	rs5987543	22532847	0.0000802	NA	NA	NA	135 prostate cancer cases; 270 controls; 525 adenoma cases; 630 colorectal cancer cases; 690 controls (shared)	NOPOP(2250)	ALL(2250)	NOPOP(2250)	ALL(2250)	Colorectal cancer	HPOID:0100834	Neoplasm of the large intestine	DOID:9256	colorectal cancer	D015179	Colorectal Neoplasms	EFOID:0000365	colorectal adenocarcinoma	Hereditary nonpolyposis colorectal tumor	NA	Research Support, Non-U.S. Gov't	T	NA

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:32)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0009404	arsenic trioxide	C006632	1327-53-3	colorectal neoplasms	MESH:D015179	therapeutic	19771260
C0009404	azacitidine	D001374	320-67-2	colorectal neoplasms	MESH:D015179	therapeutic	19934284
C0009404	carmustine	D002330	154-93-8	colorectal neoplasms	MESH:D015179	therapeutic	7960606
C0009404	celecoxib	D000068579	-	colorectal neoplasms	MESH:D015179	therapeutic	11197048
C0009404	decitabine	C014347	2353-33-5	colorectal neoplasms	MESH:D015179	therapeutic	18981723
C0009404	cisplatin	D002945	15663-27-1	colorectal neoplasms	MESH:D015179	therapeutic	15273666
C0009404	calcitriol	D002117	32222-06-3	colorectal neoplasms	MESH:D015179	therapeutic	16886663
C0009404	floxuridine	D005467	50-91-9	colorectal neoplasms	MESH:D015179	therapeutic	15040806
C0009404	fluorouracil	D005472	51-21-8	colorectal neoplasms	MESH:D015179	therapeutic	11166918
C0009404	folic acid	D005492	59-30-3	colorectal neoplasms	MESH:D015179	marker/mechanism	17087956
C0009404	folic acid	D005492	59-30-3	colorectal neoplasms	MESH:D015179	therapeutic	16963246
C0009404	leucovorin	D002955	1958/5/9	colorectal neoplasms	MESH:D015179	therapeutic	11166918
C0009404	gefitinib	C419708	184475-35-2	colorectal neoplasms	MESH:D015179	therapeutic	14639003
C0009404	gemcitabine	C056507	103882-84-4	colorectal neoplasms	MESH:D015179	therapeutic	22111927
C0009404	indomethacin	D007213	53-86-1	colorectal neoplasms	MESH:D015179	therapeutic	11197048
C0009404	meloxicam	C065757	71125-38-7	colorectal neoplasms	MESH:D015179	therapeutic	11197048
C0009404	methotrexate	D008727	1959/5/2	colorectal neoplasms	MESH:D015179	therapeutic	6327928
C0009404	mitomycin	D016685	1950/7/7	colorectal neoplasms	MESH:D015179	therapeutic	12813674
C0009404	mitoxantrone	D008942	65271-80-9	colorectal neoplasms	MESH:D015179	therapeutic	17187072
C0009404	oxaliplatin	C030110	-	colorectal neoplasms	MESH:D015179	therapeutic	11432626
C0009404	paclitaxel	D017239	-	colorectal neoplasms	MESH:D015179	therapeutic	18802399
C0009404	pyridoxal phosphate	D011732	54-47-7	colorectal neoplasms	MESH:D015179	therapeutic	18708408
C0009404	raltitrexed	C068874	-	colorectal neoplasms	MESH:D015179	therapeutic	11528249
C0009404	rofecoxib	C116926	-	colorectal neoplasms	MESH:D015179	therapeutic	15746067
C0009404	sorafenib	C471405	-	colorectal neoplasms	MESH:D015179	therapeutic	18695262
C0009404	sulindac	D013467	38194-50-2	colorectal neoplasms	MESH:D015179	therapeutic	10666051
C0009404	vinblastine	D014747	865-21-4	colorectal neoplasms	MESH:D015179	therapeutic	18802399
C0009404	vincristine	D014750	-	colorectal neoplasms	MESH:D015179	therapeutic	7960606
C0009404	vindesine	D014751	53643-48-4	colorectal neoplasms	MESH:D015179	therapeutic	6249481
C0009404	riboflavin	D012256	83-88-5	colorectal neoplasms	MESH:D015179	therapeutic	18708408
C0009404	vitamin e	D014810	1406-18-4	colorectal neoplasms	MESH:D015179	therapeutic	9359698
C0009404	zidovudine	D015215	30516-87-1	colorectal neoplasms	MESH:D015179	therapeutic	8622018

FDA approved drug and dosage information(Total Drugs:17)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D015179	calcijex	calcitriol	0.001MG/ML Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	INJECTABLE;INJECTION	Discontinued	None	Yes	No
MESH:D015179	vioxx	rofecoxib	12.5MG	TABLET;ORAL	Discontinued	None	No	No
MESH:D015179	vioxx	rofecoxib	12.5MG/5ML	SUSPENSION;ORAL	Discontinued	None	No	No
MESH:D015179	vioxx	rofecoxib	12.5MG	TABLET; ORAL	Discontinued	None	No	No
MESH:D015179	mobic	meloxicam	7.5MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D015179	mobic	meloxicam	7.5MG/5ML	SUSPENSION;ORAL	Prescription	None	Yes	Yes
MESH:D015179	celebrex	celecoxib	100MG	CAPSULE;ORAL	Prescription	AB	Yes	No
MESH:D015179	celebrex	celecoxib	100MG	CAPSULE;ORAL	Prescription	None	No	No
MESH:D015179	eloxatin	oxaliplatin	50MG/VIAL Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	INJECTABLE;IV (INFUSION)	Discontinued	None	Yes	No
MESH:D015179	eloxatin	oxaliplatin	50MG/10ML (5MG/ML)	INJECTABLE;IV (INFUSION)	Prescription	AP	Yes	Yes
MESH:D015179	oxaliplatin	oxaliplatin	50MG/10ML (5MG/ML)	INJECTABLE;IV (INFUSION)	Prescription	AP	Yes	Yes
MESH:D015179	retrovir	zidovudine	100MG	CAPSULE;ORAL	Prescription	AB	Yes	Yes
MESH:D015179	retrovir	zidovudine	50MG/5ML	SYRUP;ORAL	Prescription	AA	Yes	Yes
MESH:D015179	retrovir	zidovudine	10MG/ML	INJECTABLE;INJECTION	Prescription	AP	Yes	Yes
MESH:D015179	retrovir	zidovudine	200MG	TABLET;ORAL	Discontinued	None	No	No
MESH:D015179	zidovudine	zidovudine	60MG	TABLET;ORAL	Discontinued	None	No	No
MESH:D015179	zidovudine	zidovudine	60MG	TABLET;ORAL	Discontinued	None	No	No

FDA labeling changes(Total Drugs:17)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D015179	11/16/2001	calcijex	calcitriol	Management of hypocalcemia in patients undergoing chronic renal dialysis	The safety and effectiveness of calcitriol was examined in a double-blind placebo-controlled trial of 35 pediatric patients (13-18 years of age) with end-stage renal disease and on dialysis. The primary efficacy endpoint favored the calcitriol-treated versus the placebo-treated patients Transient hypercalcemia was seen in 1 of 16 calcitriol-treated patients; 6 of 16 (38%) calcitriol-treated patients and 2 of 19 (11%) placebo-treated patients had Ca x P >75	Labeling	B	-	-	-	Abbott	02/16/2001	FALSE'
MESH:D015179	08/19/2004	vioxx	rofecoxib	Pauciarticular or polyarticular course Juvenile Rheumatoid Arthritis	Merck announced a voluntary worldwide withdrawal of Vioxx (rofecoxib) due to safety concerns on September 30, 2004.	Labeling	B	-	-	-	Merck	02/18/2004	FALSE'
MESH:D015179	08/19/2004	vioxx	rofecoxib	Pauciarticular or polyarticular course Juvenile Rheumatoid Arthritis	Merck announced a voluntary worldwide withdrawal of Vioxx (rofecoxib) due to safety concerns on September 30, 2004.	Labeling	B	-	-	-	Merck	02/18/2004	FALSE'
MESH:D015179	08/19/2004	vioxx	rofecoxib	Pauciarticular or polyarticular course Juvenile Rheumatoid Arthritis	Merck announced a voluntary worldwide withdrawal of Vioxx (rofecoxib) due to safety concerns on September 30, 2004.	Labeling	B	-	-	-	Merck	02/18/2004	FALSE'
MESH:D015179	11/8/2005	mobic	meloxicam	Relief of signs and symptoms of pauciarticular or polyarticular course Juvenile Rheumatoid Arthritis	Safety and efficacy established in patients 2 years of age and older Clinical studies evaluated doses ranging from 0.125 mg/kg/day to 0.375 mg/kg/day. There was no additional benefit demonstrated by doses above 0.125 mg/kg/day in the clinical trials. The lowest effective dose should be used Adverse events in children were similar to those in adults including skin reactions and gastrointestinal bleed risk Information on dose, PK parameters, AE profile and clinical studies	Labeling	-	-	B, P	-	Boehringer Ingelheim	04/15/2005	FALSE'
MESH:D015179	11/8/2005	mobic	meloxicam	Relief of signs and symptoms of pauciarticular or polyarticular course Juvenile Rheumatoid Arthritis	Safety and efficacy established in patients 2 years of age and older Clinical studies evaluated doses ranging from 0.125 mg/kg/day to 0.375 mg/kg/day. There was no additional benefit demonstrated by doses above 0.125 mg/kg/day in the clinical trials. The lowest effective dose should be used Adverse events in children were similar to those in adults including skin reactions and gastrointestinal bleed risk Information on dose, PK parameters, AE profile and clinical studies	Labeling	-	-	B, P	-	Boehringer Ingelheim	04/15/2005	FALSE'
MESH:D015179	12/15/2006	celebrex	celecoxib	Relief of the signs and symptoms of juvenile rheumatoid arthritis (JRA)	New indication in 2 years and older Has not been studied in patients < 2 years, in patients with body weight < 10 kg, or in patients with active systemic features Celecoxib should be used only with caution in patients with systemic onset JRA due to the risk for serious adverse reactions including the risk of disseminated intravascular coagulation The long-term cardiovascular toxicity in children has not been evaluated; it is unknown if the long-term risk may be similar to that seen in adults New 50 mg capsule developed Information on adding contents of a capsule to applesauce. for patients with difficulty swallowing capsules Information on dose, clinical studies, PK parameters, AEs	Labeling	B	-	-	-	Pfizer	08/23/2006	FALSE'
MESH:D015179	12/15/2006	celebrex	celecoxib	Relief of the signs and symptoms of juvenile rheumatoid arthritis (JRA)	New indication in 2 years and older Has not been studied in patients < 2 years, in patients with body weight < 10 kg, or in patients with active systemic features Celecoxib should be used only with caution in patients with systemic onset JRA due to the risk for serious adverse reactions including the risk of disseminated intravascular coagulation The long-term cardiovascular toxicity in children has not been evaluated; it is unknown if the long-term risk may be similar to that seen in adults New 50 mg capsule developed Information on adding contents of a capsule to applesauce. for patients with difficulty swallowing capsules Information on dose, clinical studies, PK parameters, AEs	Labeling	B	-	-	-	Pfizer	08/23/2006	FALSE'
MESH:D015179	10/1/2007	eloxatin	oxaliplatin	Solid tumors	The effectiveness of oxaliplatin in children has not been established No significant activity observed in 2 Phase I and 2 Phase II trials in 159 patients ages 7 months to 22 years with solid tumors Information on clinical studies and AEs	Labeling	B	-	-	-	Sanofi-Aventis	09/27/2006	FALSE'
MESH:D015179	10/1/2007	eloxatin	oxaliplatin	Solid tumors	The effectiveness of oxaliplatin in children has not been established No significant activity observed in 2 Phase I and 2 Phase II trials in 159 patients ages 7 months to 22 years with solid tumors Information on clinical studies and AEs	Labeling	B	-	-	-	Sanofi-Aventis	09/27/2006	FALSE'
MESH:D015179	10/1/2007	eloxatin	oxaliplatin	Solid tumors	The effectiveness of oxaliplatin in children has not been established No significant activity observed in 2 Phase I and 2 Phase II trials in 159 patients ages 7 months to 22 years with solid tumors Information on clinical studies and AEs	Labeling	B	-	-	-	Sanofi-Aventis	09/27/2006	FALSE'
MESH:D015179	6/11/2009	retrovir	zidovudine	Treatment of HIV-1 infection in combination with other antiretroviral agents	Provided dosing recommendations for patients 4 weeks to < 6 weeks of age and weighing 4 kg to < 9 kg	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D015179	6/11/2009	retrovir	zidovudine	Treatment of HIV-1 infection in combination with other antiretroviral agents	Provided dosing recommendations for patients 4 weeks to < 6 weeks of age and weighing 4 kg to < 9 kg	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D015179	6/11/2009	retrovir	zidovudine	Treatment of HIV-1 infection in combination with other antiretroviral agents	Provided dosing recommendations for patients 4 weeks to < 6 weeks of age and weighing 4 kg to < 9 kg	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D015179	6/11/2009	retrovir	zidovudine	Treatment of HIV-1 infection in combination with other antiretroviral agents	Provided dosing recommendations for patients 4 weeks to < 6 weeks of age and weighing 4 kg to < 9 kg	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D015179	09/19/2008	retrovir syrup, capsules and tablets	zidovudine	Used in combination with 18 other antiretroviral agents for the treatment of HIV-1 infection	Dosing and administration information provided to children 6 weeks to less than 18 years of age Macrocytosis was reported in the majority of pediatric patients receiving Retrovir 180 mg/m2 every 6 hours in open-label studies New dosing regimen	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D015179	6/11/2009	retrovir	zidovudine	Treatment of HIV-1 infection in combination with other antiretroviral agents	Provided dosing recommendations for patients 4 weeks to < 6 weeks of age and weighing 4 kg to < 9 kg	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'